Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
DHDEBFGN_00001	2.33e-92	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
DHDEBFGN_00002	1.61e-57	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
DHDEBFGN_00003	2.73e-66	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
DHDEBFGN_00004	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
DHDEBFGN_00005	1.3e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
DHDEBFGN_00006	1.31e-212	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DHDEBFGN_00007	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DHDEBFGN_00008	2.08e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
DHDEBFGN_00009	1.33e-311	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DHDEBFGN_00010	9.79e-232	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
DHDEBFGN_00011	1.72e-70	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
DHDEBFGN_00012	2.06e-105	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DHDEBFGN_00013	6.59e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DHDEBFGN_00014	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
DHDEBFGN_00015	2.22e-182	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
DHDEBFGN_00016	1.52e-114	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DHDEBFGN_00017	9.17e-54	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
DHDEBFGN_00018	4.94e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
DHDEBFGN_00019	2.78e-158	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
DHDEBFGN_00020	1.28e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DHDEBFGN_00021	1.74e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
DHDEBFGN_00022	1.18e-196	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
DHDEBFGN_00023	1.63e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
DHDEBFGN_00024	2.92e-169	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
DHDEBFGN_00025	1.41e-40	-	-	-	-	-	-	-	-
DHDEBFGN_00026	5.3e-48	-	-	-	-	-	-	-	-
DHDEBFGN_00028	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DHDEBFGN_00029	2.45e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DHDEBFGN_00030	3.27e-288	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DHDEBFGN_00031	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
DHDEBFGN_00032	1.98e-166	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DHDEBFGN_00033	1.65e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DHDEBFGN_00034	1.27e-214	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DHDEBFGN_00035	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DHDEBFGN_00036	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
DHDEBFGN_00037	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DHDEBFGN_00038	5.82e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
DHDEBFGN_00039	3.05e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
DHDEBFGN_00040	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
DHDEBFGN_00041	9.22e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DHDEBFGN_00042	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
DHDEBFGN_00043	1.68e-169	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
DHDEBFGN_00044	2.23e-315	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DHDEBFGN_00045	5.61e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DHDEBFGN_00046	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DHDEBFGN_00047	4.59e-272	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DHDEBFGN_00048	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DHDEBFGN_00049	1.03e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
DHDEBFGN_00052	2.03e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DHDEBFGN_00053	1.43e-273	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DHDEBFGN_00054	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DHDEBFGN_00055	5.1e-140	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DHDEBFGN_00057	3.1e-16	-	-	-	S	-	-	-	YjcQ protein
DHDEBFGN_00058	3.66e-191	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DHDEBFGN_00059	9.35e-173	-	-	-	S	-	-	-	Membrane
DHDEBFGN_00060	9.16e-100	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
DHDEBFGN_00061	1.97e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
DHDEBFGN_00062	3.72e-300	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
DHDEBFGN_00064	6.08e-107	uspA	-	-	T	-	-	-	universal stress protein
DHDEBFGN_00065	1.7e-195	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
DHDEBFGN_00066	5.85e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
DHDEBFGN_00067	9.42e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
DHDEBFGN_00069	1.03e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
DHDEBFGN_00070	7.67e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
DHDEBFGN_00071	9.42e-234	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
DHDEBFGN_00072	2.3e-276	-	-	-	M	-	-	-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
DHDEBFGN_00073	8.07e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
DHDEBFGN_00074	2.8e-87	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
DHDEBFGN_00075	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DHDEBFGN_00076	1.78e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DHDEBFGN_00077	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DHDEBFGN_00078	1.23e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DHDEBFGN_00079	3.92e-80	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DHDEBFGN_00080	2.13e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DHDEBFGN_00081	5.66e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
DHDEBFGN_00082	1.1e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
DHDEBFGN_00083	1.35e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
DHDEBFGN_00084	8.52e-254	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
DHDEBFGN_00085	3.86e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DHDEBFGN_00086	9e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DHDEBFGN_00087	2.77e-249	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DHDEBFGN_00088	1.92e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DHDEBFGN_00089	1.53e-207	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DHDEBFGN_00090	1.78e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
DHDEBFGN_00091	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
DHDEBFGN_00092	7.49e-181	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
DHDEBFGN_00093	1.34e-62	-	-	-	-	-	-	-	-
DHDEBFGN_00094	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DHDEBFGN_00095	1.31e-245	ampC	-	-	V	-	-	-	Beta-lactamase
DHDEBFGN_00096	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
DHDEBFGN_00097	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_00098	1.02e-102	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
DHDEBFGN_00099	4.04e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
DHDEBFGN_00100	5.89e-231	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DHDEBFGN_00101	7.19e-260	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
DHDEBFGN_00102	3.78e-79	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
DHDEBFGN_00103	6.95e-301	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
DHDEBFGN_00104	1.57e-194	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
DHDEBFGN_00105	1.07e-104	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
DHDEBFGN_00106	4.84e-215	yvgN	-	-	C	-	-	-	Aldo keto reductase
DHDEBFGN_00107	1.62e-203	-	-	-	S	-	-	-	DUF218 domain
DHDEBFGN_00110	7.8e-124	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
DHDEBFGN_00111	2.58e-209	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DHDEBFGN_00112	2.46e-161	-	-	-	S	-	-	-	Phage minor capsid protein 2
DHDEBFGN_00115	1.09e-275	-	-	-	E	-	-	-	Aminotransferase
DHDEBFGN_00116	2.66e-234	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
DHDEBFGN_00117	8.17e-316	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
DHDEBFGN_00118	1.32e-125	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
DHDEBFGN_00119	4.41e-110	-	-	-	S	-	-	-	Fic/DOC family
DHDEBFGN_00120	7.24e-108	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
DHDEBFGN_00121	6.41e-96	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
DHDEBFGN_00122	5.43e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
DHDEBFGN_00123	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
DHDEBFGN_00124	2.78e-151	-	-	-	M	-	-	-	racemase activity, acting on amino acids and derivatives
DHDEBFGN_00125	6.4e-197	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
DHDEBFGN_00126	6.45e-11	eriC	-	-	P	ko:K03281	-	ko00000	chloride
DHDEBFGN_00127	3.2e-26	eriC	-	-	P	ko:K03281	-	ko00000	chloride
DHDEBFGN_00128	3.57e-22	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DHDEBFGN_00130	4.11e-310	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
DHDEBFGN_00131	3.26e-153	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
DHDEBFGN_00132	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
DHDEBFGN_00134	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
DHDEBFGN_00135	2.81e-156	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
DHDEBFGN_00136	3.98e-131	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
DHDEBFGN_00137	2.4e-312	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
DHDEBFGN_00138	1.64e-105	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
DHDEBFGN_00139	3.6e-122	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
DHDEBFGN_00140	4.65e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
DHDEBFGN_00141	7.86e-92	-	-	-	S	-	-	-	Belongs to the HesB IscA family
DHDEBFGN_00142	4.6e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
DHDEBFGN_00143	2.53e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
DHDEBFGN_00144	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DHDEBFGN_00145	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DHDEBFGN_00146	5.26e-134	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DHDEBFGN_00147	3.02e-61	-	-	-	L	-	-	-	MULE transposase domain
DHDEBFGN_00148	3.06e-15	-	-	-	-	-	-	-	-
DHDEBFGN_00150	5.92e-157	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DHDEBFGN_00151	9e-29	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DHDEBFGN_00152	0.0	dld	1.1.5.12	-	C	ko:K03777	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-lactate dehydrogenase, membrane binding
DHDEBFGN_00153	3.71e-187	-	-	-	L	-	-	-	4.5 Transposon and IS
DHDEBFGN_00154	1.9e-39	-	-	-	L	ko:K07483	-	ko00000	Transposase
DHDEBFGN_00155	2.51e-160	-	-	-	S	-	-	-	Membrane
DHDEBFGN_00156	3.18e-299	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DHDEBFGN_00157	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
DHDEBFGN_00158	2.29e-227	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
DHDEBFGN_00159	1.05e-177	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DHDEBFGN_00160	3.07e-103	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
DHDEBFGN_00161	3.03e-106	usp5	-	-	T	-	-	-	universal stress protein
DHDEBFGN_00162	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DHDEBFGN_00163	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DHDEBFGN_00164	5.97e-265	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
DHDEBFGN_00165	5.2e-98	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
DHDEBFGN_00166	3.05e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
DHDEBFGN_00167	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
DHDEBFGN_00168	3.54e-116	-	-	-	GM	-	-	-	epimerase
DHDEBFGN_00169	1.63e-110	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
DHDEBFGN_00170	4.35e-198	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
DHDEBFGN_00171	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DHDEBFGN_00172	3.78e-167	-	-	-	-	-	-	-	-
DHDEBFGN_00173	4.23e-115	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DHDEBFGN_00174	3.81e-169	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
DHDEBFGN_00175	4.33e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DHDEBFGN_00176	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
DHDEBFGN_00178	0.0	potE	-	-	E	-	-	-	Amino Acid
DHDEBFGN_00179	1.65e-241	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
DHDEBFGN_00180	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
DHDEBFGN_00181	6.06e-223	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DHDEBFGN_00182	1.74e-254	-	-	-	S	-	-	-	Domain of unknown function (DUF4432)
DHDEBFGN_00183	2.05e-147	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DHDEBFGN_00184	3.49e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
DHDEBFGN_00185	9.19e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DHDEBFGN_00186	6.06e-89	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
DHDEBFGN_00187	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
DHDEBFGN_00188	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DHDEBFGN_00190	1.74e-275	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
DHDEBFGN_00192	1.26e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
DHDEBFGN_00193	5.05e-128	-	-	-	K	-	-	-	Virulence activator alpha C-term
DHDEBFGN_00194	3.37e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
DHDEBFGN_00195	3.83e-71	-	-	-	S	-	-	-	SNARE associated Golgi protein
DHDEBFGN_00196	1.92e-304	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
DHDEBFGN_00197	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DHDEBFGN_00199	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
DHDEBFGN_00201	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DHDEBFGN_00202	3.73e-207	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
DHDEBFGN_00203	4.23e-213	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
DHDEBFGN_00204	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DHDEBFGN_00205	5.3e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DHDEBFGN_00207	1.95e-291	-	-	-	-	-	-	-	-
DHDEBFGN_00208	1.17e-249	flp	-	-	V	-	-	-	Beta-lactamase
DHDEBFGN_00209	2.02e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
DHDEBFGN_00210	5.11e-160	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
DHDEBFGN_00211	3.14e-237	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
DHDEBFGN_00212	5.4e-273	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
DHDEBFGN_00213	3.46e-207	rssA	-	-	S	-	-	-	Phospholipase, patatin family
DHDEBFGN_00214	9.12e-213	-	-	-	K	-	-	-	LysR substrate binding domain
DHDEBFGN_00215	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DHDEBFGN_00216	4.39e-109	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
DHDEBFGN_00218	7.63e-146	yicL	-	-	EG	-	-	-	EamA-like transporter family
DHDEBFGN_00219	2.18e-83	-	-	-	-	-	-	-	-
DHDEBFGN_00222	1.29e-45	-	-	-	-	-	-	-	-
DHDEBFGN_00223	3.96e-89	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
DHDEBFGN_00224	1.27e-228	-	-	-	K	-	-	-	WYL domain
DHDEBFGN_00225	4.66e-312	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
DHDEBFGN_00226	1.65e-53	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
DHDEBFGN_00227	5.78e-215	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
DHDEBFGN_00228	2.77e-270	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
DHDEBFGN_00229	1.25e-263	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
DHDEBFGN_00230	4.32e-278	-	-	-	G	-	-	-	Transporter, major facilitator family protein
DHDEBFGN_00231	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
DHDEBFGN_00232	3.45e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DHDEBFGN_00233	4.32e-71	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
DHDEBFGN_00235	3.96e-49	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
DHDEBFGN_00236	9.66e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc
DHDEBFGN_00237	9e-317	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DHDEBFGN_00238	2.41e-232	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
DHDEBFGN_00239	1.31e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DHDEBFGN_00240	1.49e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DHDEBFGN_00241	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DHDEBFGN_00242	5.5e-67	ylxQ	-	-	J	-	-	-	ribosomal protein
DHDEBFGN_00243	3.71e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
DHDEBFGN_00244	6.7e-283	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
DHDEBFGN_00245	8.99e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
DHDEBFGN_00246	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DHDEBFGN_00247	4.36e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
DHDEBFGN_00248	1.49e-252	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DHDEBFGN_00249	2.87e-263	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DHDEBFGN_00250	5.88e-176	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
DHDEBFGN_00251	3.26e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
DHDEBFGN_00252	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DHDEBFGN_00253	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DHDEBFGN_00254	6.87e-295	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
DHDEBFGN_00255	1.17e-173	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
DHDEBFGN_00256	1.56e-184	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DHDEBFGN_00257	6.51e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DHDEBFGN_00258	6.84e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
DHDEBFGN_00259	4.14e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DHDEBFGN_00260	3.14e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
DHDEBFGN_00261	2.67e-62	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
DHDEBFGN_00262	6.86e-176	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
DHDEBFGN_00263	3.06e-150	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
DHDEBFGN_00264	1.05e-36	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
DHDEBFGN_00265	1.97e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
DHDEBFGN_00266	4.36e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DHDEBFGN_00267	2.21e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
DHDEBFGN_00268	2.76e-155	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
DHDEBFGN_00269	1.52e-307	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
DHDEBFGN_00270	5.28e-108	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
DHDEBFGN_00271	5.63e-38	-	-	-	E	-	-	-	IrrE N-terminal-like domain
DHDEBFGN_00272	2.28e-117	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
DHDEBFGN_00273	8.06e-88	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DHDEBFGN_00274	1.74e-24	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DHDEBFGN_00275	3.82e-23	-	-	-	-	-	-	-	-
DHDEBFGN_00276	1.31e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DHDEBFGN_00277	4.22e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
DHDEBFGN_00278	2.92e-184	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DHDEBFGN_00279	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DHDEBFGN_00280	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
DHDEBFGN_00281	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
DHDEBFGN_00282	6.82e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DHDEBFGN_00283	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DHDEBFGN_00284	4.66e-110	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DHDEBFGN_00285	9.6e-139	-	-	-	-	-	-	-	-
DHDEBFGN_00286	4.52e-175	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DHDEBFGN_00287	9.74e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
DHDEBFGN_00288	4.21e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
DHDEBFGN_00289	2.24e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DHDEBFGN_00290	4e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DHDEBFGN_00291	2.34e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
DHDEBFGN_00292	4.12e-193	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DHDEBFGN_00293	8.4e-152	ybbR	-	-	S	-	-	-	YbbR-like protein
DHDEBFGN_00294	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DHDEBFGN_00295	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DHDEBFGN_00296	2.55e-68	-	-	-	-	-	-	-	-
DHDEBFGN_00297	2.9e-263	oatA	-	-	I	-	-	-	Acyltransferase
DHDEBFGN_00298	2.13e-193	XK27_02985	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DHDEBFGN_00299	4.69e-106	lytE	-	-	M	-	-	-	Lysin motif
DHDEBFGN_00300	6.96e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
DHDEBFGN_00301	6.02e-216	-	-	-	K	-	-	-	LysR substrate binding domain
DHDEBFGN_00302	1.64e-165	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
DHDEBFGN_00303	5.43e-192	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
DHDEBFGN_00304	8.77e-117	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
DHDEBFGN_00305	1.5e-231	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
DHDEBFGN_00306	1.82e-230	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
DHDEBFGN_00307	4.8e-164	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
DHDEBFGN_00308	7.93e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
DHDEBFGN_00309	1.27e-76	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
DHDEBFGN_00311	2.8e-170	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
DHDEBFGN_00312	0.0	yclK	-	-	T	-	-	-	Histidine kinase
DHDEBFGN_00313	3.54e-196	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
DHDEBFGN_00314	3.8e-31	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
DHDEBFGN_00315	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
DHDEBFGN_00316	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
DHDEBFGN_00317	5.03e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DHDEBFGN_00318	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
DHDEBFGN_00319	7.25e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DHDEBFGN_00320	1.2e-234	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DHDEBFGN_00321	8.31e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
DHDEBFGN_00322	2.44e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
DHDEBFGN_00323	1.73e-48	-	-	-	-	-	-	-	-
DHDEBFGN_00324	2.05e-174	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_00325	3.51e-154	-	-	-	U	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DHDEBFGN_00326	1.09e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
DHDEBFGN_00327	9.08e-71	-	-	-	-	-	-	-	-
DHDEBFGN_00328	1.72e-216	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHDEBFGN_00329	3.64e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DHDEBFGN_00330	8.79e-188	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
DHDEBFGN_00331	2.44e-120	ymdB	-	-	S	-	-	-	Macro domain protein
DHDEBFGN_00332	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
DHDEBFGN_00333	3e-291	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
DHDEBFGN_00334	1.41e-59	-	-	-	-	-	-	-	-
DHDEBFGN_00335	2.5e-270	-	-	-	S	-	-	-	Putative metallopeptidase domain
DHDEBFGN_00336	1.35e-261	-	-	-	S	-	-	-	associated with various cellular activities
DHDEBFGN_00337	2e-150	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
DHDEBFGN_00338	1.36e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
DHDEBFGN_00340	2.32e-161	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
DHDEBFGN_00341	7.49e-74	-	-	-	-	-	-	-	-
DHDEBFGN_00342	3.04e-140	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
DHDEBFGN_00343	6.55e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DHDEBFGN_00344	1.68e-138	-	-	-	-	-	-	-	-
DHDEBFGN_00345	1.11e-35	-	-	-	-	-	-	-	-
DHDEBFGN_00346	2.46e-217	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
DHDEBFGN_00347	2.56e-295	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DHDEBFGN_00348	3.55e-61	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
DHDEBFGN_00349	7.5e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
DHDEBFGN_00350	2.9e-158	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_00351	1.65e-208	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
DHDEBFGN_00352	1.58e-138	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHDEBFGN_00353	5.52e-241	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
DHDEBFGN_00354	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
DHDEBFGN_00359	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
DHDEBFGN_00360	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DHDEBFGN_00361	4.42e-307	yycH	-	-	S	-	-	-	YycH protein
DHDEBFGN_00362	2.79e-183	yycI	-	-	S	-	-	-	YycH protein
DHDEBFGN_00363	5.49e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
DHDEBFGN_00364	9.52e-270	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
DHDEBFGN_00365	1.18e-104	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DHDEBFGN_00366	3.03e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
DHDEBFGN_00367	2.68e-224	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
DHDEBFGN_00368	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
DHDEBFGN_00369	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
DHDEBFGN_00370	5.19e-148	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
DHDEBFGN_00371	2.56e-143	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
DHDEBFGN_00372	2.97e-244	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DHDEBFGN_00373	2.32e-234	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
DHDEBFGN_00374	2.3e-230	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHDEBFGN_00375	5.66e-277	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DHDEBFGN_00376	1.15e-47	-	-	-	-	-	-	-	-
DHDEBFGN_00377	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
DHDEBFGN_00378	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DHDEBFGN_00379	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DHDEBFGN_00380	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
DHDEBFGN_00381	1.26e-210	-	-	-	C	-	-	-	Aldo keto reductase
DHDEBFGN_00382	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
DHDEBFGN_00383	3.67e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
DHDEBFGN_00384	1.3e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
DHDEBFGN_00385	6.55e-166	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DHDEBFGN_00386	4.91e-56	-	-	-	K	-	-	-	transcriptional regulator
DHDEBFGN_00387	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
DHDEBFGN_00388	2.85e-135	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
DHDEBFGN_00389	2.46e-217	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
DHDEBFGN_00390	1.4e-145	cat	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
DHDEBFGN_00391	1.69e-277	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
DHDEBFGN_00392	1.34e-197	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
DHDEBFGN_00393	8.06e-141	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
DHDEBFGN_00394	4.4e-122	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DHDEBFGN_00395	5.32e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DHDEBFGN_00396	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_00397	1.07e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DHDEBFGN_00398	1.29e-211	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
DHDEBFGN_00399	2.52e-300	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
DHDEBFGN_00400	2.65e-53	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DHDEBFGN_00401	1.5e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
DHDEBFGN_00402	4.63e-275	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
DHDEBFGN_00403	2.29e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
DHDEBFGN_00404	4.37e-76	-	-	-	M	-	-	-	Lysin motif
DHDEBFGN_00405	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
DHDEBFGN_00406	1.1e-253	-	-	-	S	-	-	-	Helix-turn-helix domain
DHDEBFGN_00407	2.03e-112	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DHDEBFGN_00408	1.68e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
DHDEBFGN_00409	3.2e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DHDEBFGN_00410	2.05e-183	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DHDEBFGN_00411	2.23e-89	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DHDEBFGN_00412	1.84e-185	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
DHDEBFGN_00413	6.26e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
DHDEBFGN_00414	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
DHDEBFGN_00415	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
DHDEBFGN_00417	5.92e-300	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
DHDEBFGN_00418	6.96e-201	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DHDEBFGN_00419	3.81e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
DHDEBFGN_00420	5.64e-153	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
DHDEBFGN_00421	8.31e-294	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
DHDEBFGN_00422	1.1e-120	-	-	-	S	-	-	-	Protein conserved in bacteria
DHDEBFGN_00423	5.75e-227	-	-	-	-	-	-	-	-
DHDEBFGN_00424	1.9e-201	-	-	-	-	-	-	-	-
DHDEBFGN_00425	4.76e-19	-	-	-	-	-	-	-	-
DHDEBFGN_00426	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
DHDEBFGN_00427	2.56e-220	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DHDEBFGN_00428	3.51e-33	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
DHDEBFGN_00429	5.91e-93	yqhL	-	-	P	-	-	-	Rhodanese-like protein
DHDEBFGN_00430	1.83e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
DHDEBFGN_00431	1.14e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
DHDEBFGN_00432	1.68e-148	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
DHDEBFGN_00433	3.66e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DHDEBFGN_00434	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
DHDEBFGN_00435	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DHDEBFGN_00436	0.0	-	-	-	S	-	-	-	membrane
DHDEBFGN_00437	1.81e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DHDEBFGN_00438	5.91e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
DHDEBFGN_00439	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DHDEBFGN_00440	4.45e-253	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DHDEBFGN_00441	1.44e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
DHDEBFGN_00442	4.08e-117	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DHDEBFGN_00443	1.84e-180	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DHDEBFGN_00444	8.13e-62	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
DHDEBFGN_00445	1.13e-196	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DHDEBFGN_00446	4.54e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
DHDEBFGN_00447	8.94e-297	-	-	-	V	-	-	-	MatE
DHDEBFGN_00448	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
DHDEBFGN_00449	1.38e-155	csrR	-	-	K	-	-	-	response regulator
DHDEBFGN_00450	7.89e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
DHDEBFGN_00451	2.79e-126	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
DHDEBFGN_00452	1.37e-272	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
DHDEBFGN_00453	3.16e-181	yqeM	-	-	Q	-	-	-	Methyltransferase
DHDEBFGN_00454	2.79e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DHDEBFGN_00455	5.53e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
DHDEBFGN_00456	2.29e-120	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DHDEBFGN_00457	1.38e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
DHDEBFGN_00458	2.29e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
DHDEBFGN_00459	6.88e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
DHDEBFGN_00460	7.57e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
DHDEBFGN_00461	2.58e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
DHDEBFGN_00462	4.67e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DHDEBFGN_00463	5.22e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
DHDEBFGN_00464	6.95e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DHDEBFGN_00465	1.08e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
DHDEBFGN_00466	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
DHDEBFGN_00467	3.44e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DHDEBFGN_00468	4.15e-137	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DHDEBFGN_00469	8.84e-207	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DHDEBFGN_00470	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DHDEBFGN_00471	1.14e-178	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
DHDEBFGN_00472	5.05e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
DHDEBFGN_00473	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
DHDEBFGN_00474	1.11e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DHDEBFGN_00475	1.53e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
DHDEBFGN_00476	6.83e-76	-	-	-	S	-	-	-	Small secreted protein
DHDEBFGN_00477	9.51e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DHDEBFGN_00478	6.32e-274	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
DHDEBFGN_00479	7.43e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_00480	4.29e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
DHDEBFGN_00482	6.67e-192	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DHDEBFGN_00483	5.23e-230	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
DHDEBFGN_00484	3.95e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
DHDEBFGN_00485	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
DHDEBFGN_00486	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
DHDEBFGN_00488	4.86e-53	-	-	-	-	-	-	-	-
DHDEBFGN_00490	2.45e-256	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
DHDEBFGN_00491	7.57e-135	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
DHDEBFGN_00492	8.26e-309	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
DHDEBFGN_00493	1.13e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
DHDEBFGN_00494	7.52e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
DHDEBFGN_00495	9.96e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DHDEBFGN_00496	4.99e-153	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DHDEBFGN_00497	6.39e-235	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
DHDEBFGN_00498	1.21e-143	-	-	-	-	-	-	-	-
DHDEBFGN_00499	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
DHDEBFGN_00500	1.33e-239	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DHDEBFGN_00501	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
DHDEBFGN_00502	1.65e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
DHDEBFGN_00503	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
DHDEBFGN_00504	9.4e-199	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DHDEBFGN_00505	4.9e-83	-	-	-	S	-	-	-	Domain of unknown function DUF302
DHDEBFGN_00506	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
DHDEBFGN_00507	9.88e-57	-	-	-	-	-	-	-	-
DHDEBFGN_00508	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
DHDEBFGN_00509	2.93e-163	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
DHDEBFGN_00510	7.27e-285	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DHDEBFGN_00511	1.87e-180	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DHDEBFGN_00512	3.78e-271	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DHDEBFGN_00513	3.23e-64	-	-	-	-	-	-	-	-
DHDEBFGN_00514	4.67e-127	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
DHDEBFGN_00515	0.0	-	-	-	EGP	-	-	-	Major Facilitator
DHDEBFGN_00516	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
DHDEBFGN_00517	1.37e-315	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DHDEBFGN_00518	3.91e-31	-	-	-	-	-	-	-	-
DHDEBFGN_00521	1.26e-63	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
DHDEBFGN_00522	1.28e-67	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
DHDEBFGN_00523	1.03e-120	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
DHDEBFGN_00524	1.22e-154	-	-	-	Q	-	-	-	Methyltransferase domain
DHDEBFGN_00526	2e-135	-	-	-	S	-	-	-	CAAX protease self-immunity
DHDEBFGN_00527	5.3e-130	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DHDEBFGN_00528	1.23e-101	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DHDEBFGN_00529	9.79e-62	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
DHDEBFGN_00530	6.87e-131	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DHDEBFGN_00531	4.82e-277	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DHDEBFGN_00532	7.36e-135	-	-	-	-	-	-	-	-
DHDEBFGN_00533	1.76e-113	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
DHDEBFGN_00534	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
DHDEBFGN_00535	2.89e-44	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
DHDEBFGN_00536	1.05e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DHDEBFGN_00537	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DHDEBFGN_00538	1.29e-205	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DHDEBFGN_00539	1.27e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
DHDEBFGN_00540	5.17e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
DHDEBFGN_00541	4.94e-244	mocA	-	-	S	-	-	-	Oxidoreductase
DHDEBFGN_00542	1.42e-305	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
DHDEBFGN_00544	3.25e-97	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
DHDEBFGN_00545	1.66e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
DHDEBFGN_00546	4.77e-214	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
DHDEBFGN_00547	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
DHDEBFGN_00548	5.86e-192	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
DHDEBFGN_00549	4.37e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
DHDEBFGN_00551	8.33e-188	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
DHDEBFGN_00552	1.73e-152	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
DHDEBFGN_00553	6.95e-191	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
DHDEBFGN_00554	1.1e-43	-	-	-	M	-	-	-	biosynthesis protein
DHDEBFGN_00555	1.16e-80	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
DHDEBFGN_00556	1.63e-90	-	-	-	-	-	-	-	-
DHDEBFGN_00557	1.74e-106	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
DHDEBFGN_00558	1.11e-94	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
DHDEBFGN_00560	9.46e-199	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DHDEBFGN_00561	1.28e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DHDEBFGN_00562	0.0	-	-	-	L	-	-	-	DNA helicase
DHDEBFGN_00563	7.95e-222	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DHDEBFGN_00564	1.93e-286	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
DHDEBFGN_00565	3.73e-239	-	-	-	-	-	-	-	-
DHDEBFGN_00566	2.31e-165	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
DHDEBFGN_00567	2.38e-272	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
DHDEBFGN_00568	9.96e-209	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
DHDEBFGN_00569	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DHDEBFGN_00570	3.29e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
DHDEBFGN_00571	7.92e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DHDEBFGN_00572	2.07e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DHDEBFGN_00573	4.04e-205	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DHDEBFGN_00574	3.47e-213	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
DHDEBFGN_00575	1.98e-123	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
DHDEBFGN_00576	4.65e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
DHDEBFGN_00577	1.44e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
DHDEBFGN_00578	9.91e-302	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DHDEBFGN_00579	7.69e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DHDEBFGN_00580	1.89e-78	-	-	-	-	-	-	-	-
DHDEBFGN_00581	4.1e-184	yidA	-	-	S	-	-	-	hydrolase
DHDEBFGN_00582	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
DHDEBFGN_00583	5.23e-97	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
DHDEBFGN_00584	2.16e-97	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DHDEBFGN_00585	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DHDEBFGN_00586	4.36e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DHDEBFGN_00587	3.85e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
DHDEBFGN_00588	1.59e-37	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
DHDEBFGN_00589	5.38e-158	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
DHDEBFGN_00591	7.83e-301	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DHDEBFGN_00592	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
DHDEBFGN_00593	3.68e-278	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DHDEBFGN_00594	9.8e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
DHDEBFGN_00595	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHDEBFGN_00596	1.07e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
DHDEBFGN_00597	3.78e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHDEBFGN_00598	3.78e-307	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DHDEBFGN_00599	2.53e-153	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
DHDEBFGN_00600	6.28e-147	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DHDEBFGN_00601	6.55e-311	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DHDEBFGN_00602	6.62e-279	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
DHDEBFGN_00603	2.13e-141	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DHDEBFGN_00604	2.85e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DHDEBFGN_00605	2.71e-197	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DHDEBFGN_00606	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
DHDEBFGN_00607	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
DHDEBFGN_00608	3.97e-62	-	-	-	-	-	-	-	-
DHDEBFGN_00609	7.45e-25	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
DHDEBFGN_00610	6.19e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DHDEBFGN_00611	2.38e-168	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DHDEBFGN_00612	8.04e-124	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DHDEBFGN_00613	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
DHDEBFGN_00614	9.69e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DHDEBFGN_00615	2.81e-212	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DHDEBFGN_00616	8.19e-50	-	-	-	K	-	-	-	transcriptional regulator
DHDEBFGN_00617	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
DHDEBFGN_00618	1.04e-245	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
DHDEBFGN_00619	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
DHDEBFGN_00620	2.5e-109	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
DHDEBFGN_00621	2.14e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DHDEBFGN_00622	1.28e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
DHDEBFGN_00623	2.3e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
DHDEBFGN_00624	2e-45	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
DHDEBFGN_00625	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
DHDEBFGN_00626	1.25e-31	-	-	-	S	-	-	-	Virus attachment protein p12 family
DHDEBFGN_00627	1.1e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
DHDEBFGN_00628	2.2e-227	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DHDEBFGN_00629	2.41e-235	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHDEBFGN_00630	4.3e-277	aspB3	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
DHDEBFGN_00631	2.61e-117	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DHDEBFGN_00632	4.79e-250	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
DHDEBFGN_00633	7.83e-301	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DHDEBFGN_00634	9.4e-133	-	-	-	-	-	-	-	-
DHDEBFGN_00635	1.88e-272	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DHDEBFGN_00636	7.56e-15	aroH	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
DHDEBFGN_00637	8.63e-274	-	-	-	G	-	-	-	Major Facilitator Superfamily
DHDEBFGN_00639	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
DHDEBFGN_00642	1.51e-194	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
DHDEBFGN_00643	7.06e-58	-	-	-	GM	-	-	-	NAD(P)H-binding
DHDEBFGN_00644	6.38e-118	-	-	-	GM	-	-	-	NAD(P)H-binding
DHDEBFGN_00645	6.65e-169	-	-	-	S	-	-	-	Alpha beta hydrolase
DHDEBFGN_00646	5.61e-301	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
DHDEBFGN_00648	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
DHDEBFGN_00649	9.2e-57	-	-	-	-	-	-	-	-
DHDEBFGN_00652	2.39e-254	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
DHDEBFGN_00653	1.59e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DHDEBFGN_00654	9.84e-175	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DHDEBFGN_00655	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DHDEBFGN_00656	1.24e-145	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
DHDEBFGN_00658	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DHDEBFGN_00659	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DHDEBFGN_00660	7.52e-263	-	-	-	-	-	-	-	-
DHDEBFGN_00661	2.25e-205	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
DHDEBFGN_00662	3.31e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
DHDEBFGN_00663	6.71e-214	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
DHDEBFGN_00664	5.35e-101	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DHDEBFGN_00665	7.02e-22	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DHDEBFGN_00666	2.96e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DHDEBFGN_00670	1.22e-23	-	-	-	S	-	-	-	zinc-ribbon domain
DHDEBFGN_00672	1.03e-81	-	-	-	-	-	-	-	-
DHDEBFGN_00673	7.68e-24	-	-	-	S	-	-	-	zinc-ribbon domain
DHDEBFGN_00674	2.03e-312	-	-	-	V	-	-	-	Eco57I restriction-modification methylase
DHDEBFGN_00675	0.0	-	-	-	S	-	-	-	PglZ domain
DHDEBFGN_00676	0.0	-	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	Putative ATP-dependent Lon protease
DHDEBFGN_00677	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
DHDEBFGN_00679	2.05e-291	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
DHDEBFGN_00680	2.92e-05	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
DHDEBFGN_00681	1.16e-222	ydbI	-	-	K	-	-	-	AI-2E family transporter
DHDEBFGN_00682	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
DHDEBFGN_00683	8.26e-106	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DHDEBFGN_00684	3.25e-273	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DHDEBFGN_00685	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DHDEBFGN_00686	8.02e-221	hrpQ	4.6.1.1	-	T	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	histone H2A K63-linked ubiquitination
DHDEBFGN_00687	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
DHDEBFGN_00688	6.13e-174	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
DHDEBFGN_00689	1.36e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DHDEBFGN_00690	4.87e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DHDEBFGN_00691	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DHDEBFGN_00692	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DHDEBFGN_00693	3.94e-250	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
DHDEBFGN_00694	1.13e-139	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DHDEBFGN_00695	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
DHDEBFGN_00696	1.12e-306	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
DHDEBFGN_00697	9.44e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DHDEBFGN_00698	1.35e-283	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DHDEBFGN_00699	7.08e-227	-	-	-	-	-	-	-	-
DHDEBFGN_00700	1.07e-67	-	-	-	S	-	-	-	Cupredoxin-like domain
DHDEBFGN_00701	2.79e-69	-	-	-	S	-	-	-	Cupredoxin-like domain
DHDEBFGN_00702	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
DHDEBFGN_00703	1.14e-37	-	-	-	EGP	-	-	-	Major Facilitator
DHDEBFGN_00704	6.87e-117	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
DHDEBFGN_00705	1.92e-05	-	-	-	UW	-	-	-	Tetratricopeptide repeat
DHDEBFGN_00706	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
DHDEBFGN_00707	4.37e-164	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
DHDEBFGN_00708	9.03e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
DHDEBFGN_00709	9.95e-108	-	-	-	F	-	-	-	Hydrolase, NUDIX family
DHDEBFGN_00710	1.07e-271	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
DHDEBFGN_00711	0.0	fusA1	-	-	J	-	-	-	elongation factor G
DHDEBFGN_00712	2.08e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DHDEBFGN_00713	7.3e-143	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
DHDEBFGN_00714	5.72e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DHDEBFGN_00715	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
DHDEBFGN_00716	6.64e-205	-	-	-	EG	-	-	-	EamA-like transporter family
DHDEBFGN_00717	1.41e-244	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
DHDEBFGN_00718	1.64e-184	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
DHDEBFGN_00719	3.41e-172	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
DHDEBFGN_00720	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
DHDEBFGN_00721	6.66e-115	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
DHDEBFGN_00722	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
DHDEBFGN_00723	5.33e-215	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
DHDEBFGN_00724	7.43e-231	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
DHDEBFGN_00725	1.42e-271	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
DHDEBFGN_00726	5.29e-263	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DHDEBFGN_00727	3.39e-120	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DHDEBFGN_00728	9e-11	-	-	-	C	-	-	-	Domain of unknown function (DUF4145)
DHDEBFGN_00729	1.06e-17	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
DHDEBFGN_00730	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DHDEBFGN_00731	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DHDEBFGN_00732	3.04e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DHDEBFGN_00733	1.45e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
DHDEBFGN_00734	3.2e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DHDEBFGN_00735	9.49e-317	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DHDEBFGN_00737	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
DHDEBFGN_00738	2.64e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DHDEBFGN_00739	4.99e-187	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DHDEBFGN_00740	1.5e-197	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
DHDEBFGN_00741	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DHDEBFGN_00742	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DHDEBFGN_00743	1.77e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DHDEBFGN_00744	1.25e-283	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
DHDEBFGN_00745	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
DHDEBFGN_00746	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DHDEBFGN_00747	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DHDEBFGN_00748	1.16e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
DHDEBFGN_00749	8.83e-209	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
DHDEBFGN_00750	8.27e-111	-	-	-	L	-	-	-	nuclease
DHDEBFGN_00751	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DHDEBFGN_00752	9.57e-69	-	-	-	-	-	-	-	-
DHDEBFGN_00755	7.77e-19	-	-	-	-	ko:K18640	-	ko00000,ko04812	-
DHDEBFGN_00756	6.25e-07	ydiL	-	-	S	ko:K07052	-	ko00000	protease
DHDEBFGN_00760	2.33e-33	-	-	-	M	-	-	-	CHAP domain
DHDEBFGN_00762	4.18e-228	-	-	-	U	-	-	-	type IV secretory pathway VirB4
DHDEBFGN_00763	1.95e-27	-	-	-	-	-	-	-	-
DHDEBFGN_00766	7.63e-59	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
DHDEBFGN_00768	6.3e-75	-	-	-	-	-	-	-	-
DHDEBFGN_00769	2.73e-268	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
DHDEBFGN_00773	2.11e-177	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
DHDEBFGN_00776	8.53e-168	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
DHDEBFGN_00777	1.64e-65	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
DHDEBFGN_00780	4.7e-42	-	-	-	L	ko:K07483	-	ko00000	Transposase
DHDEBFGN_00781	5.15e-246	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
DHDEBFGN_00782	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
DHDEBFGN_00783	2.36e-215	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
DHDEBFGN_00784	1.15e-198	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
DHDEBFGN_00785	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
DHDEBFGN_00787	1.2e-262	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DHDEBFGN_00789	2.83e-104	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
DHDEBFGN_00790	7.62e-53	-	-	-	-	-	-	-	-
DHDEBFGN_00791	7.04e-217	-	-	-	GK	-	-	-	ROK family
DHDEBFGN_00792	1.75e-165	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
DHDEBFGN_00793	9.56e-166	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
DHDEBFGN_00794	1.95e-210	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
DHDEBFGN_00795	6.33e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
DHDEBFGN_00796	2.51e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DHDEBFGN_00797	3.49e-72	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DHDEBFGN_00798	6.33e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DHDEBFGN_00799	8.78e-55	repA	-	-	S	-	-	-	Replication initiator protein A
DHDEBFGN_00800	6.73e-111	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
DHDEBFGN_00801	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DHDEBFGN_00802	1.44e-59	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DHDEBFGN_00803	1.4e-27	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
DHDEBFGN_00808	1.12e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DHDEBFGN_00809	2.95e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DHDEBFGN_00810	1.98e-261	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
DHDEBFGN_00811	1.46e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
DHDEBFGN_00812	3.03e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
DHDEBFGN_00813	9.49e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DHDEBFGN_00814	5.39e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DHDEBFGN_00815	9.32e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
DHDEBFGN_00816	7.55e-206	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
DHDEBFGN_00817	2.01e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DHDEBFGN_00818	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
DHDEBFGN_00819	4.5e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
DHDEBFGN_00820	9.82e-76	-	-	-	-	-	-	-	-
DHDEBFGN_00821	1.23e-105	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
DHDEBFGN_00822	5.37e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DHDEBFGN_00823	5.28e-31	ftsL	-	-	D	-	-	-	Cell division protein FtsL
DHDEBFGN_00824	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
DHDEBFGN_00825	1.82e-226	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DHDEBFGN_00826	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DHDEBFGN_00827	2.06e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DHDEBFGN_00828	5.43e-193	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DHDEBFGN_00829	4.88e-300	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DHDEBFGN_00830	1.23e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DHDEBFGN_00831	4.13e-99	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DHDEBFGN_00832	7.27e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
DHDEBFGN_00833	2.49e-186	ylmH	-	-	S	-	-	-	S4 domain protein
DHDEBFGN_00834	6.19e-143	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
DHDEBFGN_00836	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DHDEBFGN_00837	9.99e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
DHDEBFGN_00838	4.28e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
DHDEBFGN_00840	3.26e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DHDEBFGN_00841	1.31e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
DHDEBFGN_00842	3.43e-283	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DHDEBFGN_00843	0.0	-	-	-	S	-	-	-	amidohydrolase
DHDEBFGN_00844	8.89e-218	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
DHDEBFGN_00845	4.33e-154	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
DHDEBFGN_00846	9.37e-159	-	-	-	S	-	-	-	repeat protein
DHDEBFGN_00847	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DHDEBFGN_00848	3.81e-228	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DHDEBFGN_00849	2.39e-98	-	-	-	P	-	-	-	ArsC family
DHDEBFGN_00850	2.95e-239	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
DHDEBFGN_00851	8.83e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
DHDEBFGN_00852	6.12e-98	-	-	-	-	-	-	-	-
DHDEBFGN_00853	8.59e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DHDEBFGN_00854	1.55e-65	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
DHDEBFGN_00855	9.34e-176	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
DHDEBFGN_00856	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
DHDEBFGN_00857	3.64e-271	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
DHDEBFGN_00858	1.31e-63	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
DHDEBFGN_00859	1.27e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
DHDEBFGN_00860	2.93e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DHDEBFGN_00861	1.38e-252	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
DHDEBFGN_00862	1.47e-127	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
DHDEBFGN_00863	8.66e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
DHDEBFGN_00864	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
DHDEBFGN_00865	9.44e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
DHDEBFGN_00866	2.9e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
DHDEBFGN_00867	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DHDEBFGN_00868	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DHDEBFGN_00869	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DHDEBFGN_00870	4.68e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
DHDEBFGN_00871	7.02e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DHDEBFGN_00872	1.15e-299	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DHDEBFGN_00873	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DHDEBFGN_00874	2.17e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
DHDEBFGN_00875	2.23e-69	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
DHDEBFGN_00877	2.3e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_00878	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DHDEBFGN_00879	1.15e-315	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DHDEBFGN_00880	8.64e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DHDEBFGN_00881	1.3e-199	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
DHDEBFGN_00882	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
DHDEBFGN_00883	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DHDEBFGN_00884	6.69e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
DHDEBFGN_00885	1.84e-237	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHDEBFGN_00886	6.41e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
DHDEBFGN_00887	3.54e-57	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
DHDEBFGN_00888	2.7e-126	ydeQ	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
DHDEBFGN_00889	1.93e-28	-	-	-	S	-	-	-	Protein conserved in bacteria
DHDEBFGN_00890	3.03e-74	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
DHDEBFGN_00891	4.48e-67	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
DHDEBFGN_00892	2.47e-13	-	-	-	K	-	-	-	transcriptional
DHDEBFGN_00893	7.11e-253	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
DHDEBFGN_00894	1.4e-27	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
DHDEBFGN_00895	7.51e-50	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
DHDEBFGN_00896	7.95e-153	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
DHDEBFGN_00897	2.24e-11	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
DHDEBFGN_00899	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
DHDEBFGN_00901	1.73e-17	-	-	-	S	-	-	-	CHY zinc finger
DHDEBFGN_00903	1.94e-16	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
DHDEBFGN_00905	4.88e-236	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
DHDEBFGN_00906	9.97e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
DHDEBFGN_00907	1.65e-128	-	-	-	-	-	-	-	-
DHDEBFGN_00910	1.8e-112	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DHDEBFGN_00912	2.1e-06	-	-	-	S	-	-	-	sequence-specific DNA binding
DHDEBFGN_00926	1.81e-17	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DHDEBFGN_00930	4.72e-151	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DHDEBFGN_00931	5.46e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DHDEBFGN_00932	2.79e-174	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
DHDEBFGN_00933	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DHDEBFGN_00934	2.72e-314	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
DHDEBFGN_00935	3.45e-175	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
DHDEBFGN_00937	2.16e-98	uspA3	-	-	T	-	-	-	universal stress protein
DHDEBFGN_00938	6.25e-78	-	-	-	-	-	-	-	-
DHDEBFGN_00939	1.25e-09	-	-	-	-	-	-	-	-
DHDEBFGN_00940	1.92e-203	-	-	-	-	-	-	-	-
DHDEBFGN_00941	2.22e-98	-	-	-	K	-	-	-	Transcriptional regulator
DHDEBFGN_00942	1.77e-238	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
DHDEBFGN_00943	9.46e-96	-	-	-	O	-	-	-	OsmC-like protein
DHDEBFGN_00944	8.24e-248	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
DHDEBFGN_00945	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DHDEBFGN_00946	1.78e-22	-	-	-	-	-	-	-	-
DHDEBFGN_00947	1.96e-145	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
DHDEBFGN_00948	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_00949	4.09e-131	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
DHDEBFGN_00950	3.41e-231	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
DHDEBFGN_00951	2.51e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
DHDEBFGN_00952	7.02e-57	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
DHDEBFGN_00953	8.5e-142	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DHDEBFGN_00954	2.84e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
DHDEBFGN_00955	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
DHDEBFGN_00956	3.23e-215	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DHDEBFGN_00957	2.61e-163	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DHDEBFGN_00958	1.25e-212	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
DHDEBFGN_00959	7.85e-242	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
DHDEBFGN_00960	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
DHDEBFGN_00962	2e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
DHDEBFGN_00963	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
DHDEBFGN_00964	4.68e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DHDEBFGN_00965	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DHDEBFGN_00966	8.7e-166	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
DHDEBFGN_00967	1.56e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
DHDEBFGN_00968	4e-150	-	-	-	-	-	-	-	-
DHDEBFGN_00971	9.6e-212	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DHDEBFGN_00972	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
DHDEBFGN_00973	6.5e-238	-	-	-	D	-	-	-	nuclear chromosome segregation
DHDEBFGN_00974	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
DHDEBFGN_00975	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DHDEBFGN_00976	4.73e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DHDEBFGN_00977	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DHDEBFGN_00978	5.21e-126	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
DHDEBFGN_00979	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DHDEBFGN_00980	1.65e-113	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
DHDEBFGN_00981	5.88e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
DHDEBFGN_00982	2.47e-53	yabO	-	-	J	-	-	-	S4 domain protein
DHDEBFGN_00983	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DHDEBFGN_00984	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DHDEBFGN_00985	4.51e-148	-	-	-	S	-	-	-	(CBS) domain
DHDEBFGN_00986	7.09e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
DHDEBFGN_00987	6.25e-268	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DHDEBFGN_00988	1.18e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DHDEBFGN_00989	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DHDEBFGN_00990	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DHDEBFGN_00991	1.9e-202	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
DHDEBFGN_00992	1.66e-119	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
DHDEBFGN_00993	4.97e-59	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DHDEBFGN_00994	5.55e-72	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
DHDEBFGN_00995	9.26e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
DHDEBFGN_00996	7.48e-298	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
DHDEBFGN_00997	3.09e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
DHDEBFGN_00999	2.77e-172	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_01000	6.23e-192	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
DHDEBFGN_01001	3.41e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
DHDEBFGN_01002	6.16e-34	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
DHDEBFGN_01003	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
DHDEBFGN_01004	1.35e-261	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
DHDEBFGN_01005	8.3e-141	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
DHDEBFGN_01006	1.64e-108	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
DHDEBFGN_01007	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DHDEBFGN_01008	3.77e-217	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
DHDEBFGN_01009	8.41e-235	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
DHDEBFGN_01010	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
DHDEBFGN_01011	5.93e-149	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
DHDEBFGN_01012	2.73e-227	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
DHDEBFGN_01013	6.7e-81	-	-	-	-	-	-	-	-
DHDEBFGN_01014	5.49e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DHDEBFGN_01015	8.4e-88	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DHDEBFGN_01016	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
DHDEBFGN_01017	1.41e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DHDEBFGN_01018	9.91e-66	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DHDEBFGN_01019	1.54e-10	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DHDEBFGN_01020	1.86e-63	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DHDEBFGN_01021	2.1e-214	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
DHDEBFGN_01022	1.06e-277	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DHDEBFGN_01023	1.84e-139	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
DHDEBFGN_01024	6.33e-293	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DHDEBFGN_01025	4.39e-133	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
DHDEBFGN_01026	1.21e-143	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DHDEBFGN_01027	1.88e-164	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DHDEBFGN_01028	6.34e-182	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DHDEBFGN_01029	7.56e-73	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DHDEBFGN_01030	2.63e-69	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
DHDEBFGN_01031	1.28e-254	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DHDEBFGN_01032	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DHDEBFGN_01033	1.07e-286	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DHDEBFGN_01034	2.43e-98	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
DHDEBFGN_01035	4.95e-201	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
DHDEBFGN_01036	4.39e-133	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
DHDEBFGN_01037	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DHDEBFGN_01039	8.24e-18	-	-	-	L	ko:K07483	-	ko00000	Transposase
DHDEBFGN_01041	2.7e-162	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
DHDEBFGN_01042	1.31e-76	-	-	-	S	-	-	-	AAA domain
DHDEBFGN_01043	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
DHDEBFGN_01044	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
DHDEBFGN_01045	7.11e-75	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
DHDEBFGN_01046	1.15e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase
DHDEBFGN_01047	1.06e-186	-	-	-	L	-	-	-	4.5 Transposon and IS
DHDEBFGN_01048	6.26e-55	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
DHDEBFGN_01049	7.31e-17	-	-	-	S	-	-	-	Protein of unknown function (DUF3892)
DHDEBFGN_01050	1.74e-95	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
DHDEBFGN_01052	5.52e-61	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
DHDEBFGN_01053	3.43e-174	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DHDEBFGN_01054	3.16e-67	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DHDEBFGN_01055	3.04e-12	-	-	-	M	-	-	-	Glycosyl transferase family 2
DHDEBFGN_01056	1.47e-121	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
DHDEBFGN_01057	3.89e-165	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
DHDEBFGN_01058	3.96e-178	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
DHDEBFGN_01059	3.81e-151	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
DHDEBFGN_01060	5.09e-165	epsB	-	-	M	-	-	-	biosynthesis protein
DHDEBFGN_01061	2.85e-221	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
DHDEBFGN_01062	1.41e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DHDEBFGN_01063	6.52e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
DHDEBFGN_01064	7.12e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DHDEBFGN_01065	1.47e-41	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
DHDEBFGN_01066	5.07e-187	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DHDEBFGN_01067	6.65e-209	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
DHDEBFGN_01068	2.48e-171	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
DHDEBFGN_01069	2.31e-185	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
DHDEBFGN_01070	4.43e-272	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
DHDEBFGN_01071	7.59e-238	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DHDEBFGN_01072	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DHDEBFGN_01073	3.89e-94	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
DHDEBFGN_01074	3.73e-26	-	-	-	S	-	-	-	Glycosyltransferase like family 2
DHDEBFGN_01075	5.72e-130	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
DHDEBFGN_01076	7.62e-219	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DHDEBFGN_01077	2.08e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
DHDEBFGN_01078	4.5e-199	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_01081	6.84e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
DHDEBFGN_01082	4.44e-208	-	-	-	EG	-	-	-	EamA-like transporter family
DHDEBFGN_01083	2.99e-176	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DHDEBFGN_01084	1.15e-182	-	-	-	G	-	-	-	MucBP domain
DHDEBFGN_01085	8.07e-126	-	-	-	S	-	-	-	Pfam:DUF3816
DHDEBFGN_01086	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DHDEBFGN_01087	7.08e-142	pncA	-	-	Q	-	-	-	Isochorismatase family
DHDEBFGN_01088	1.44e-165	-	-	-	F	-	-	-	NUDIX domain
DHDEBFGN_01089	2.15e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
DHDEBFGN_01091	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
DHDEBFGN_01092	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
DHDEBFGN_01093	4.84e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_01094	1.87e-171	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
DHDEBFGN_01095	8.44e-113	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
DHDEBFGN_01096	3.24e-60	yrfB	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
DHDEBFGN_01097	5.27e-97	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
DHDEBFGN_01098	1.89e-74	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
DHDEBFGN_01100	2.4e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
DHDEBFGN_01101	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
DHDEBFGN_01102	8.17e-286	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
DHDEBFGN_01103	5.97e-194	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DHDEBFGN_01104	1.48e-183	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
DHDEBFGN_01105	3.15e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
DHDEBFGN_01106	3.88e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DHDEBFGN_01107	8.24e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DHDEBFGN_01108	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
DHDEBFGN_01109	4.17e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
DHDEBFGN_01110	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
DHDEBFGN_01111	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DHDEBFGN_01112	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
DHDEBFGN_01113	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
DHDEBFGN_01114	8.93e-250	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DHDEBFGN_01115	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DHDEBFGN_01116	6.56e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
DHDEBFGN_01117	1.5e-112	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DHDEBFGN_01119	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DHDEBFGN_01120	3.97e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DHDEBFGN_01121	6.48e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DHDEBFGN_01122	2.06e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
DHDEBFGN_01123	2.41e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DHDEBFGN_01124	2.25e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
DHDEBFGN_01125	5.8e-248	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
DHDEBFGN_01126	2.47e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
DHDEBFGN_01127	2.83e-202	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DHDEBFGN_01128	3.31e-188	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
DHDEBFGN_01129	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DHDEBFGN_01130	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DHDEBFGN_01131	6.5e-219	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
DHDEBFGN_01132	3.48e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
DHDEBFGN_01133	7.82e-203	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
DHDEBFGN_01134	2.08e-239	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DHDEBFGN_01135	4.08e-218	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
DHDEBFGN_01136	3.45e-305	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
DHDEBFGN_01137	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
DHDEBFGN_01138	4.65e-279	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
DHDEBFGN_01139	1.61e-274	arcT	-	-	E	-	-	-	Aminotransferase
DHDEBFGN_01140	3.39e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
DHDEBFGN_01141	5.55e-143	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
DHDEBFGN_01142	3.65e-250	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DHDEBFGN_01144	3.83e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DHDEBFGN_01145	1.32e-97	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
DHDEBFGN_01146	2.18e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DHDEBFGN_01147	4.18e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DHDEBFGN_01148	1.78e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
DHDEBFGN_01149	2.67e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
DHDEBFGN_01150	3.79e-291	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DHDEBFGN_01151	3.46e-94	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DHDEBFGN_01152	1.13e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DHDEBFGN_01153	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
DHDEBFGN_01154	1.78e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DHDEBFGN_01155	4.46e-180	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
DHDEBFGN_01156	1.55e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
DHDEBFGN_01157	1.67e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
DHDEBFGN_01158	1.04e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DHDEBFGN_01159	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
DHDEBFGN_01160	8.05e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DHDEBFGN_01161	1.15e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DHDEBFGN_01162	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DHDEBFGN_01163	0.0	ydaO	-	-	E	-	-	-	amino acid
DHDEBFGN_01164	4.12e-50	-	-	-	-	-	-	-	-
DHDEBFGN_01165	5.69e-147	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
DHDEBFGN_01166	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
DHDEBFGN_01167	3.57e-165	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
DHDEBFGN_01168	4.64e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DHDEBFGN_01169	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DHDEBFGN_01170	2.5e-258	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DHDEBFGN_01171	1.97e-70	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
DHDEBFGN_01172	4.15e-69	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
DHDEBFGN_01173	1.13e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DHDEBFGN_01174	3.09e-208	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DHDEBFGN_01175	9.09e-236	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
DHDEBFGN_01176	3.11e-219	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
DHDEBFGN_01177	1.06e-188	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
DHDEBFGN_01178	7.28e-288	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DHDEBFGN_01179	5.1e-240	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DHDEBFGN_01180	2.23e-101	yphH	-	-	S	-	-	-	Cupin domain
DHDEBFGN_01181	6.74e-166	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DHDEBFGN_01182	2.83e-199	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
DHDEBFGN_01183	7.3e-216	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
DHDEBFGN_01184	3.14e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
DHDEBFGN_01185	2.17e-274	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
DHDEBFGN_01186	9.46e-87	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
DHDEBFGN_01187	1.28e-78	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
DHDEBFGN_01188	1.84e-60	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
DHDEBFGN_01190	8.95e-55	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DHDEBFGN_01191	7.32e-51	-	-	-	M	-	-	-	KxYKxGKxW signal domain protein
DHDEBFGN_01192	1.09e-67	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
DHDEBFGN_01193	4.14e-09	-	-	-	-	-	-	-	-
DHDEBFGN_01194	6.59e-204	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
DHDEBFGN_01195	6.94e-218	yueF	-	-	S	-	-	-	AI-2E family transporter
DHDEBFGN_01197	8.21e-216	-	-	-	H	-	-	-	geranyltranstransferase activity
DHDEBFGN_01198	8.42e-236	-	-	-	-	-	-	-	-
DHDEBFGN_01199	1.99e-53	-	-	-	-	-	-	-	-
DHDEBFGN_01200	1.83e-150	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
DHDEBFGN_01201	9.81e-241	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
DHDEBFGN_01202	4.99e-101	nreA	-	-	T	ko:K10851	ko02020,map02020	ko00000,ko00001	GAF domain
DHDEBFGN_01203	6.94e-54	-	-	-	-	-	-	-	-
DHDEBFGN_01204	7.14e-128	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
DHDEBFGN_01205	1.11e-107	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
DHDEBFGN_01206	5.2e-294	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
DHDEBFGN_01207	2.18e-112	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
DHDEBFGN_01208	5.12e-243	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
DHDEBFGN_01209	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DHDEBFGN_01210	0.0	-	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
DHDEBFGN_01211	2.15e-132	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	Nitrate reductase delta subunit
DHDEBFGN_01212	7.16e-163	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
DHDEBFGN_01214	3.72e-145	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
DHDEBFGN_01215	4.01e-140	-	-	-	C	-	-	-	aldo keto reductase
DHDEBFGN_01216	5.06e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DHDEBFGN_01217	2.07e-282	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHDEBFGN_01218	0.0	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
DHDEBFGN_01219	4.56e-102	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
DHDEBFGN_01220	1.14e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
DHDEBFGN_01221	3.92e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
DHDEBFGN_01222	1.52e-137	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
DHDEBFGN_01223	3.99e-258	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DHDEBFGN_01224	2.01e-70	-	-	-	C	-	-	-	FMN binding
DHDEBFGN_01225	1.86e-75	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
DHDEBFGN_01226	8.9e-62	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
DHDEBFGN_01227	2.49e-19	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
DHDEBFGN_01228	3.17e-281	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
DHDEBFGN_01230	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
DHDEBFGN_01231	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DHDEBFGN_01232	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
DHDEBFGN_01233	3.3e-121	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
DHDEBFGN_01234	1.02e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
DHDEBFGN_01235	2.84e-240	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DHDEBFGN_01236	3.56e-219	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DHDEBFGN_01237	2.17e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
DHDEBFGN_01239	7.46e-194	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
DHDEBFGN_01240	2.57e-226	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
DHDEBFGN_01241	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
DHDEBFGN_01242	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
DHDEBFGN_01243	4.83e-36	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DHDEBFGN_01244	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DHDEBFGN_01245	1e-272	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
DHDEBFGN_01246	7.95e-250	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
DHDEBFGN_01247	3.07e-135	-	-	-	NU	-	-	-	mannosyl-glycoprotein
DHDEBFGN_01248	1.03e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
DHDEBFGN_01249	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
DHDEBFGN_01250	4.35e-108	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
DHDEBFGN_01251	9.42e-95	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
DHDEBFGN_01252	1.27e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
DHDEBFGN_01253	9.97e-245	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
DHDEBFGN_01254	1.59e-86	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DHDEBFGN_01255	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
DHDEBFGN_01256	2.85e-163	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
DHDEBFGN_01257	1.55e-274	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
DHDEBFGN_01258	1.79e-266	-	-	-	EGP	-	-	-	Major Facilitator
DHDEBFGN_01259	6.97e-204	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
DHDEBFGN_01260	7.3e-89	-	-	-	-	-	-	-	-
DHDEBFGN_01261	2.97e-12	-	-	-	S	-	-	-	YSIRK type signal peptide
DHDEBFGN_01262	2.25e-301	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
DHDEBFGN_01263	4.45e-181	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_01264	4.25e-199	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHDEBFGN_01265	7.99e-196	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
DHDEBFGN_01266	1.13e-130	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
DHDEBFGN_01267	0.0	-	-	-	M	-	-	-	Iron Transport-associated domain
DHDEBFGN_01268	1.59e-81	-	-	-	-	-	-	-	-
DHDEBFGN_01269	8.58e-71	-	4.1.1.44	-	O	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DHDEBFGN_01270	5.03e-43	ydzE	-	-	EG	-	-	-	spore germination
DHDEBFGN_01271	1.55e-120	-	-	-	P	-	-	-	Cadmium resistance transporter
DHDEBFGN_01282	8.21e-07	-	-	-	K	-	-	-	Transcriptional regulator
DHDEBFGN_01283	3.37e-19	ebrB	-	-	U	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
DHDEBFGN_01284	9.64e-183	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
DHDEBFGN_01285	4.53e-145	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DHDEBFGN_01286	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
DHDEBFGN_01287	2.56e-145	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DHDEBFGN_01288	1.07e-208	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
DHDEBFGN_01289	2.63e-301	-	-	-	F	ko:K03458	-	ko00000	Permease
DHDEBFGN_01290	3.01e-256	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
DHDEBFGN_01291	2.41e-87	-	-	-	M	-	-	-	LysM domain protein
DHDEBFGN_01292	3.6e-112	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
DHDEBFGN_01293	6.84e-103	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
DHDEBFGN_01294	3.96e-122	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
DHDEBFGN_01295	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
DHDEBFGN_01296	8.97e-252	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DHDEBFGN_01297	1.06e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
DHDEBFGN_01298	1.98e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DHDEBFGN_01299	1.58e-159	-	-	-	C	-	-	-	nitroreductase
DHDEBFGN_01300	2.48e-225	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
DHDEBFGN_01301	8.01e-24	fdrA	-	-	C	ko:K02381	-	ko00000	CoA-ligase
DHDEBFGN_01302	5.7e-121	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
DHDEBFGN_01303	2.69e-102	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
DHDEBFGN_01304	2.03e-123	allC	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	Peptidase family M20/M25/M40
DHDEBFGN_01305	1.38e-168	-	3.5.2.3, 3.5.2.5	-	F	ko:K01465,ko:K01466	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DHDEBFGN_01306	3.8e-76	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
DHDEBFGN_01307	8.91e-28	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
DHDEBFGN_01308	9.74e-73	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
DHDEBFGN_01309	3.82e-33	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
DHDEBFGN_01310	1.39e-232	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHDEBFGN_01311	8.45e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DHDEBFGN_01312	3.51e-183	yceF	-	-	P	ko:K05794	-	ko00000	membrane
DHDEBFGN_01313	1.42e-215	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
DHDEBFGN_01314	3.93e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DHDEBFGN_01315	1.85e-300	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
DHDEBFGN_01316	5.62e-192	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
DHDEBFGN_01317	3.31e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
DHDEBFGN_01318	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DHDEBFGN_01319	1.3e-110	-	-	-	-	-	-	-	-
DHDEBFGN_01320	3.81e-142	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
DHDEBFGN_01321	4.64e-129	dpsB	-	-	P	-	-	-	Belongs to the Dps family
DHDEBFGN_01322	7.55e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
DHDEBFGN_01323	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
DHDEBFGN_01331	1.18e-56	-	-	-	-	-	-	-	-
DHDEBFGN_01333	7.66e-84	-	-	-	S	-	-	-	Fic/DOC family
DHDEBFGN_01334	1.49e-130	cadD	-	-	P	-	-	-	Cadmium resistance transporter
DHDEBFGN_01335	1.55e-151	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
DHDEBFGN_01336	2.41e-134	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DHDEBFGN_01337	2.52e-203	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
DHDEBFGN_01338	4.53e-127	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DHDEBFGN_01339	4.59e-49	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
DHDEBFGN_01340	5.69e-87	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
DHDEBFGN_01341	7.95e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
DHDEBFGN_01342	5.05e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DHDEBFGN_01343	4.46e-184	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
DHDEBFGN_01344	1.01e-179	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DHDEBFGN_01345	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DHDEBFGN_01346	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DHDEBFGN_01347	1.13e-118	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DHDEBFGN_01348	8.39e-47	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DHDEBFGN_01349	1.07e-41	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
DHDEBFGN_01351	4.74e-42	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
DHDEBFGN_01352	1.9e-42	-	-	-	I	ko:K01066	-	ko00000,ko01000	Esterase lipase
DHDEBFGN_01354	3.26e-128	-	-	-	S	-	-	-	integral membrane protein
DHDEBFGN_01355	8.4e-280	-	-	-	L	-	-	-	Probable transposase
DHDEBFGN_01356	3.36e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DHDEBFGN_01358	4.82e-72	-	-	-	-	-	-	-	-
DHDEBFGN_01359	1.54e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
DHDEBFGN_01360	2.59e-175	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DHDEBFGN_01361	4.23e-76	-	-	-	-	-	-	-	-
DHDEBFGN_01362	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DHDEBFGN_01363	3.12e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DHDEBFGN_01364	8.67e-110	-	-	-	K	-	-	-	Transcriptional regulator
DHDEBFGN_01365	5.68e-279	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
DHDEBFGN_01366	3.1e-269	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
DHDEBFGN_01368	6.31e-78	yxeM	-	-	ET	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
DHDEBFGN_01369	1.03e-59	yxeL	-	-	K	-	-	-	acetyltransferase
DHDEBFGN_01370	1.2e-98	yxeN	-	-	U	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
DHDEBFGN_01371	6.15e-100	yxeO	-	-	E	ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
DHDEBFGN_01372	8.5e-185	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
DHDEBFGN_01373	3.62e-215	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
DHDEBFGN_01374	1.73e-107	-	-	-	S	-	-	-	MmgE/PrpD family
DHDEBFGN_01376	3.39e-147	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
DHDEBFGN_01377	6.82e-149	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
DHDEBFGN_01378	4.83e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_01379	5.25e-197	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
DHDEBFGN_01380	3.15e-175	-	-	-	IQ	-	-	-	KR domain
DHDEBFGN_01382	2.87e-271	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
DHDEBFGN_01383	1.07e-112	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
DHDEBFGN_01384	7.42e-77	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
DHDEBFGN_01385	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
DHDEBFGN_01386	1.95e-221	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
DHDEBFGN_01387	3.92e-217	-	-	-	G	-	-	-	Phosphotransferase enzyme family
DHDEBFGN_01388	3.81e-227	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
DHDEBFGN_01389	4.43e-250	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
DHDEBFGN_01390	1.39e-314	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
DHDEBFGN_01391	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DHDEBFGN_01392	1.1e-165	-	-	-	F	-	-	-	glutamine amidotransferase
DHDEBFGN_01393	3.81e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
DHDEBFGN_01394	1.52e-93	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
DHDEBFGN_01395	1.75e-228	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
DHDEBFGN_01396	2.39e-103	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DHDEBFGN_01397	4.42e-87	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
DHDEBFGN_01398	2.56e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DHDEBFGN_01399	5.3e-200	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
DHDEBFGN_01400	2.08e-239	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
DHDEBFGN_01401	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
DHDEBFGN_01402	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DHDEBFGN_01403	6.97e-264	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DHDEBFGN_01404	5.7e-199	is18	-	-	L	-	-	-	Integrase core domain
DHDEBFGN_01405	6.66e-27	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
DHDEBFGN_01406	2.24e-113	-	-	-	-	-	-	-	-
DHDEBFGN_01407	3.56e-31	-	-	-	S	-	-	-	Small integral membrane protein (DUF2273)
DHDEBFGN_01408	8.87e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
DHDEBFGN_01409	1.19e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
DHDEBFGN_01410	4.74e-23	-	-	-	-	-	-	-	-
DHDEBFGN_01411	1.37e-218	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
DHDEBFGN_01412	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
DHDEBFGN_01413	2.34e-301	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
DHDEBFGN_01414	1.39e-233	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
DHDEBFGN_01415	1.59e-80	-	-	-	-	-	-	-	-
DHDEBFGN_01416	2.95e-284	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
DHDEBFGN_01417	1.69e-124	-	-	-	V	-	-	-	VanZ like family
DHDEBFGN_01418	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
DHDEBFGN_01419	3.24e-61	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
DHDEBFGN_01420	7.8e-44	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
DHDEBFGN_01421	2.91e-99	-	-	-	-	-	-	-	-
DHDEBFGN_01422	3.71e-236	-	-	-	-	-	-	-	-
DHDEBFGN_01424	2.06e-171	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
DHDEBFGN_01425	1.93e-209	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
DHDEBFGN_01426	2.36e-77	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DHDEBFGN_01427	9.41e-278	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
DHDEBFGN_01428	6.78e-249	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DHDEBFGN_01429	2.34e-47	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
DHDEBFGN_01430	7.91e-95	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
DHDEBFGN_01431	2.02e-76	-	-	-	S	-	-	-	Flavodoxin
DHDEBFGN_01432	3.08e-220	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHDEBFGN_01433	1.5e-182	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DHDEBFGN_01434	5.4e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
DHDEBFGN_01435	3.62e-72	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
DHDEBFGN_01436	1.04e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF1858)
DHDEBFGN_01437	0.0	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
DHDEBFGN_01438	6.79e-183	-	-	-	EG	-	-	-	EamA-like transporter family
DHDEBFGN_01439	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
DHDEBFGN_01440	1.28e-158	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DHDEBFGN_01441	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
DHDEBFGN_01442	6.35e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_01443	5.66e-288	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
DHDEBFGN_01445	2e-239	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DHDEBFGN_01447	1.13e-98	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
DHDEBFGN_01448	4.65e-72	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
DHDEBFGN_01449	3.55e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
DHDEBFGN_01450	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DHDEBFGN_01451	7.84e-264	yacL	-	-	S	-	-	-	domain protein
DHDEBFGN_01452	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DHDEBFGN_01453	9.63e-130	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
DHDEBFGN_01454	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
DHDEBFGN_01455	1.25e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DHDEBFGN_01456	1.01e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DHDEBFGN_01457	5.57e-135	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
DHDEBFGN_01458	7.09e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
DHDEBFGN_01459	2.48e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DHDEBFGN_01460	1.18e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
DHDEBFGN_01461	3.34e-68	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DHDEBFGN_01462	1.38e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DHDEBFGN_01463	1.28e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DHDEBFGN_01464	9.79e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
DHDEBFGN_01465	5.43e-182	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DHDEBFGN_01466	3e-221	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DHDEBFGN_01467	1.34e-279	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DHDEBFGN_01468	6.39e-115	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DHDEBFGN_01469	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DHDEBFGN_01470	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
DHDEBFGN_01471	5.03e-232	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DHDEBFGN_01472	4.95e-216	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DHDEBFGN_01473	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
DHDEBFGN_01474	4.92e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
DHDEBFGN_01475	6.61e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
DHDEBFGN_01476	2.41e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
DHDEBFGN_01477	1.64e-25	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DHDEBFGN_01478	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DHDEBFGN_01479	1.16e-205	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DHDEBFGN_01480	9.82e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DHDEBFGN_01481	2.1e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
DHDEBFGN_01482	1.99e-261	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DHDEBFGN_01483	8.74e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
DHDEBFGN_01484	1.2e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
DHDEBFGN_01485	1.09e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
DHDEBFGN_01486	3.17e-149	-	-	-	K	-	-	-	Transcriptional regulator
DHDEBFGN_01488	3.29e-50	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
DHDEBFGN_01489	4.36e-155	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
DHDEBFGN_01490	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
DHDEBFGN_01491	2.43e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
DHDEBFGN_01492	2.57e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DHDEBFGN_01493	1.8e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DHDEBFGN_01494	8.6e-93	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
DHDEBFGN_01495	1.22e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
DHDEBFGN_01496	2.25e-138	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
DHDEBFGN_01497	1.45e-200	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
DHDEBFGN_01498	1.43e-153	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DHDEBFGN_01499	6.44e-22	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DHDEBFGN_01500	9.3e-220	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
DHDEBFGN_01501	2.24e-198	-	-	-	D	-	-	-	DNA integration
DHDEBFGN_01502	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DHDEBFGN_01503	5.14e-212	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
DHDEBFGN_01504	4.82e-179	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DHDEBFGN_01505	1.03e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DHDEBFGN_01506	5.17e-125	-	-	-	L	-	-	-	DNA integration
DHDEBFGN_01507	1.02e-30	-	-	-	-	-	-	-	-
DHDEBFGN_01508	9.56e-99	-	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
DHDEBFGN_01515	3.1e-100	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
DHDEBFGN_01518	3.65e-45	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma-70 factor, region 1.1
DHDEBFGN_01519	1.51e-30	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
DHDEBFGN_01523	2.22e-14	-	-	-	U	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03110	Preprotein translocase subunit SecB
DHDEBFGN_01524	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DHDEBFGN_01525	4.03e-261	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
DHDEBFGN_01526	8.97e-95	-	-	-	F	-	-	-	Nudix hydrolase
DHDEBFGN_01527	9.61e-137	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
DHDEBFGN_01528	7.28e-110	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
DHDEBFGN_01529	7.65e-10	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
DHDEBFGN_01530	5.54e-214	-	-	-	-	-	-	-	-
DHDEBFGN_01531	9.7e-252	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
DHDEBFGN_01532	4.94e-121	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
DHDEBFGN_01533	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
DHDEBFGN_01534	6.96e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
DHDEBFGN_01535	8.01e-129	-	-	-	-	-	-	-	-
DHDEBFGN_01536	1.01e-171	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
DHDEBFGN_01537	1.76e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
DHDEBFGN_01538	1.02e-145	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
DHDEBFGN_01539	8.44e-128	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DHDEBFGN_01540	9.87e-203	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DHDEBFGN_01541	1.77e-298	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
DHDEBFGN_01542	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
DHDEBFGN_01543	2.07e-116	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
DHDEBFGN_01544	7.76e-72	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
DHDEBFGN_01545	1.48e-42	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
DHDEBFGN_01546	5.26e-14	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
DHDEBFGN_01547	2.83e-231	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
DHDEBFGN_01548	1.75e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
DHDEBFGN_01549	6.74e-270	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DHDEBFGN_01550	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
DHDEBFGN_01551	1.67e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
DHDEBFGN_01552	2.58e-276	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DHDEBFGN_01553	2.27e-74	lysR	-	-	K	-	-	-	Transcriptional regulator
DHDEBFGN_01554	5.18e-17	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
DHDEBFGN_01555	4.47e-247	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
DHDEBFGN_01556	9.73e-126	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DHDEBFGN_01558	4.08e-65	-	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Peptidase S24-like
DHDEBFGN_01559	0.000161	-	-	-	K	ko:K07729	-	ko00000,ko03000	DNA-binding helix-turn-helix protein
DHDEBFGN_01560	5.23e-120	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
DHDEBFGN_01564	2e-13	-	-	-	-	-	-	-	-
DHDEBFGN_01566	7.77e-20	-	-	-	S	-	-	-	HNH endonuclease
DHDEBFGN_01569	2.65e-93	-	-	-	S	-	-	-	AAA domain
DHDEBFGN_01571	7.22e-153	-	-	-	S	-	-	-	calcium ion binding
DHDEBFGN_01572	4.06e-56	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
DHDEBFGN_01576	2.43e-56	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
DHDEBFGN_01582	5.49e-192	-	-	-	S	-	-	-	HNH endonuclease
DHDEBFGN_01583	2.83e-99	-	-	-	S	-	-	-	Phage terminase, small subunit
DHDEBFGN_01584	0.0	-	-	-	S	-	-	-	Phage Terminase
DHDEBFGN_01586	1.24e-296	-	-	-	S	-	-	-	Phage portal protein
DHDEBFGN_01587	6.72e-247	-	-	-	S	-	-	-	peptidase activity
DHDEBFGN_01588	1.09e-66	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
DHDEBFGN_01589	1.79e-29	-	-	-	S	-	-	-	Phage head-tail joining protein
DHDEBFGN_01590	2.49e-49	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
DHDEBFGN_01591	1.9e-54	-	-	-	-	-	-	-	-
DHDEBFGN_01592	8.8e-142	-	-	-	S	-	-	-	Pfam:Phage_TTP_1
DHDEBFGN_01594	3.69e-20	-	-	-	-	-	-	-	-
DHDEBFGN_01595	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
DHDEBFGN_01596	3.33e-195	-	-	-	S	-	-	-	Phage tail protein
DHDEBFGN_01597	3.58e-135	-	-	-	S	-	-	-	Peptidase family M23
DHDEBFGN_01598	1.66e-20	spoIVFA	-	GT2,GT4	D	ko:K05802,ko:K06401,ko:K20444,ko:K22051	-	ko00000,ko01000,ko01005,ko02000	peptidase
DHDEBFGN_01602	3.79e-73	-	-	-	-	-	-	-	-
DHDEBFGN_01606	1.04e-25	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
DHDEBFGN_01607	1.75e-115	-	-	-	M	-	-	-	hydrolase, family 25
DHDEBFGN_01612	1.97e-15	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
DHDEBFGN_01613	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
DHDEBFGN_01614	1.8e-271	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
DHDEBFGN_01615	6.51e-202	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
DHDEBFGN_01616	1.53e-214	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
DHDEBFGN_01617	3.52e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DHDEBFGN_01618	8.22e-305	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHDEBFGN_01619	1.52e-208	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
DHDEBFGN_01620	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
DHDEBFGN_01621	1.14e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
DHDEBFGN_01622	9.75e-232	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DHDEBFGN_01623	3.81e-255	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
DHDEBFGN_01624	9.72e-295	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
DHDEBFGN_01625	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DHDEBFGN_01626	2.14e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
DHDEBFGN_01627	2.41e-07	-	-	-	-	-	-	-	-
DHDEBFGN_01628	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
DHDEBFGN_01629	2.03e-250	bdhA	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
DHDEBFGN_01630	9.78e-231	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
DHDEBFGN_01631	7.95e-132	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
DHDEBFGN_01632	5.43e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_01633	1.8e-138	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
DHDEBFGN_01634	2.84e-209	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
DHDEBFGN_01635	8.57e-92	ywnA	-	-	K	-	-	-	Transcriptional regulator
DHDEBFGN_01636	5.23e-97	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
DHDEBFGN_01637	9.22e-96	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
DHDEBFGN_01638	7.45e-28	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
DHDEBFGN_01639	8.35e-121	-	-	-	L	-	-	-	Probable transposase
DHDEBFGN_01640	9.63e-210	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DHDEBFGN_01641	8.32e-66	-	-	-	-	-	-	-	-
DHDEBFGN_01642	1.79e-267	-	-	-	E	-	-	-	Major Facilitator Superfamily
DHDEBFGN_01643	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
DHDEBFGN_01644	2.63e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DHDEBFGN_01645	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
DHDEBFGN_01646	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DHDEBFGN_01647	7.22e-153	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DHDEBFGN_01648	6.02e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
DHDEBFGN_01649	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
DHDEBFGN_01650	3.19e-115	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
DHDEBFGN_01651	2.29e-96	-	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	Amidinotransferase
DHDEBFGN_01653	4.35e-247	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
DHDEBFGN_01654	1.29e-235	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
DHDEBFGN_01655	3.69e-31	-	-	-	D	ko:K19158	-	ko00000,ko01000,ko02048	mRNA cleavage
DHDEBFGN_01656	9.21e-19	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
DHDEBFGN_01657	7.96e-125	-	-	-	L	-	-	-	MULE transposase domain
DHDEBFGN_01658	5.27e-237	hoxN	-	-	U	ko:K07241	-	ko00000,ko02000	High-affinity nickel-transport protein
DHDEBFGN_01659	3.27e-191	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
DHDEBFGN_01660	1.33e-166	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
DHDEBFGN_01661	1.3e-301	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DHDEBFGN_01662	2.36e-168	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
DHDEBFGN_01663	1.24e-305	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
DHDEBFGN_01664	1.24e-160	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
DHDEBFGN_01665	2.11e-191	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
DHDEBFGN_01666	2.77e-64	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DHDEBFGN_01667	4.59e-248	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DHDEBFGN_01668	1.15e-158	cas4	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	Domain of unknown function DUF83
DHDEBFGN_01669	1.83e-201	csd2	-	-	L	ko:K19115,ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
DHDEBFGN_01670	0.0	csd1	-	-	M	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
DHDEBFGN_01671	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
DHDEBFGN_01673	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DHDEBFGN_01674	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
DHDEBFGN_01675	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
DHDEBFGN_01676	7.43e-08	-	-	-	C	-	-	-	Aldo/keto reductase family
DHDEBFGN_01679	1.68e-57	-	-	-	C	-	-	-	Aldo keto reductase
DHDEBFGN_01680	1.47e-30	-	-	-	C	-	-	-	reductase
DHDEBFGN_01681	1.69e-99	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
DHDEBFGN_01682	9.46e-106	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
DHDEBFGN_01683	1.84e-155	pnb	-	-	C	-	-	-	nitroreductase
DHDEBFGN_01684	9.9e-09	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
DHDEBFGN_01685	2.69e-57	yodA	-	-	S	-	-	-	Tautomerase enzyme
DHDEBFGN_01687	3.77e-28	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
DHDEBFGN_01688	1.05e-209	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
DHDEBFGN_01689	3.47e-79	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DHDEBFGN_01690	1.17e-122	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DHDEBFGN_01691	3.43e-176	-	-	-	L	-	-	-	PFAM Integrase catalytic region
DHDEBFGN_01693	1.74e-111	-	-	-	K	-	-	-	GNAT family
DHDEBFGN_01694	1.27e-158	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
DHDEBFGN_01695	9.18e-206	yvgN	-	-	S	-	-	-	Aldo keto reductase
DHDEBFGN_01696	2.6e-184	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DHDEBFGN_01697	1.4e-168	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
DHDEBFGN_01699	1.55e-74	-	-	-	-	-	-	-	-
DHDEBFGN_01701	2.33e-10	-	-	-	-	-	-	-	-
DHDEBFGN_01702	7.83e-65	-	-	-	K	-	-	-	TRANSCRIPTIONal
DHDEBFGN_01703	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DHDEBFGN_01704	8.8e-238	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
DHDEBFGN_01705	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DHDEBFGN_01706	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DHDEBFGN_01707	6.72e-63	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DHDEBFGN_01708	8.01e-226	camS	-	-	S	-	-	-	sex pheromone
DHDEBFGN_01709	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DHDEBFGN_01710	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
DHDEBFGN_01711	7.47e-280	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DHDEBFGN_01712	3.89e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DHDEBFGN_01713	2.33e-142	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
DHDEBFGN_01714	4.28e-178	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
DHDEBFGN_01715	8.46e-263	-	-	-	S	-	-	-	interspecies interaction between organisms
DHDEBFGN_01716	2.78e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
DHDEBFGN_01717	5.57e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DHDEBFGN_01718	8.08e-188	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DHDEBFGN_01719	9.25e-178	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DHDEBFGN_01720	2.06e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DHDEBFGN_01721	1.5e-193	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DHDEBFGN_01722	1.02e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
DHDEBFGN_01723	3.48e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DHDEBFGN_01724	8.02e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DHDEBFGN_01725	1.32e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DHDEBFGN_01726	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
DHDEBFGN_01727	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DHDEBFGN_01728	2.16e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DHDEBFGN_01729	7.83e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DHDEBFGN_01730	3.5e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
DHDEBFGN_01731	6.96e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
DHDEBFGN_01732	3.59e-113	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DHDEBFGN_01733	5.55e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DHDEBFGN_01734	2.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DHDEBFGN_01735	2.19e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DHDEBFGN_01736	2.46e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DHDEBFGN_01737	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DHDEBFGN_01738	3.02e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DHDEBFGN_01739	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DHDEBFGN_01740	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DHDEBFGN_01741	1.35e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
DHDEBFGN_01742	2.78e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DHDEBFGN_01743	3.43e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DHDEBFGN_01744	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DHDEBFGN_01745	1.51e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DHDEBFGN_01746	3.32e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DHDEBFGN_01747	2.76e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DHDEBFGN_01748	1.56e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
DHDEBFGN_01749	5.89e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DHDEBFGN_01750	3.14e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
DHDEBFGN_01751	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DHDEBFGN_01752	4.15e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DHDEBFGN_01753	3.58e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DHDEBFGN_01754	2.5e-40	pilD	3.4.23.43	-	NOU	ko:K02236,ko:K02506,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	aspartic-type endopeptidase activity
DHDEBFGN_01755	2.13e-275	-	-	-	-	-	-	-	-
DHDEBFGN_01756	2.92e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
DHDEBFGN_01757	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DHDEBFGN_01758	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DHDEBFGN_01759	3.46e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHDEBFGN_01760	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DHDEBFGN_01761	6.36e-103	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
DHDEBFGN_01762	7.92e-247	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DHDEBFGN_01763	4.84e-170	XK27_07210	-	-	S	-	-	-	B3 4 domain
DHDEBFGN_01764	4.27e-154	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
DHDEBFGN_01765	7.3e-51	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
DHDEBFGN_01766	3.94e-52	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
DHDEBFGN_01767	2.89e-94	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
DHDEBFGN_01768	7.76e-53	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
DHDEBFGN_01769	4.07e-22	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
DHDEBFGN_01770	4.82e-189	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DHDEBFGN_01771	2.47e-40	-	-	-	IQ	-	-	-	reductase
DHDEBFGN_01772	2.98e-23	-	-	-	IQ	-	-	-	reductase
DHDEBFGN_01773	5.16e-15	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DHDEBFGN_01779	4.69e-151	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
DHDEBFGN_01780	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
DHDEBFGN_01782	3.45e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DHDEBFGN_01783	3.13e-149	-	-	-	I	-	-	-	phosphatase
DHDEBFGN_01784	8.17e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
DHDEBFGN_01785	1.11e-160	-	-	-	S	-	-	-	Putative threonine/serine exporter
DHDEBFGN_01786	4.74e-125	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DHDEBFGN_01787	6.48e-120	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
DHDEBFGN_01788	1.75e-157	vanR	-	-	K	-	-	-	response regulator
DHDEBFGN_01789	7.59e-268	hpk31	-	-	T	-	-	-	Histidine kinase
DHDEBFGN_01790	5.61e-268	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
DHDEBFGN_01791	2.17e-187	-	-	-	E	-	-	-	AzlC protein
DHDEBFGN_01792	2.22e-78	-	-	-	S	-	-	-	branched-chain amino acid
DHDEBFGN_01793	2.06e-51	-	-	-	L	-	-	-	Probable transposase
DHDEBFGN_01794	1.02e-32	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
DHDEBFGN_01795	5.19e-55	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
DHDEBFGN_01796	1.53e-87	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DHDEBFGN_01797	3.34e-70	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
DHDEBFGN_01798	3.14e-20	-	-	-	C	-	-	-	Flavodoxin
DHDEBFGN_01799	2.39e-28	-	-	-	GM	-	-	-	NmrA-like family
DHDEBFGN_01800	5.08e-14	-	-	-	S	-	-	-	NAD(P)H dehydrogenase (quinone) activity
DHDEBFGN_01801	1.38e-114	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
DHDEBFGN_01802	1.28e-145	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
DHDEBFGN_01803	4.86e-61	-	-	-	D	-	-	-	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DHDEBFGN_01804	1.04e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
DHDEBFGN_01805	0.0	-	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
DHDEBFGN_01806	8.12e-106	-	-	-	-	-	-	-	-
DHDEBFGN_01807	6.26e-138	-	-	-	L	-	-	-	Integrase
DHDEBFGN_01808	8.66e-88	-	-	-	I	-	-	-	Alpha/beta hydrolase family
DHDEBFGN_01809	2.24e-58	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
DHDEBFGN_01810	5.91e-80	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
DHDEBFGN_01811	4.1e-48	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
DHDEBFGN_01812	9.16e-08	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
DHDEBFGN_01813	1.35e-109	-	-	-	K	-	-	-	FR47-like protein
DHDEBFGN_01814	3.98e-312	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
DHDEBFGN_01815	1.02e-26	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
DHDEBFGN_01816	7.57e-79	-	-	-	M	-	-	-	Glycosyl transferase family 2
DHDEBFGN_01817	4.75e-118	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
DHDEBFGN_01818	1.57e-10	-	-	-	S	-	-	-	Acetyltransferase (Isoleucine patch superfamily)
DHDEBFGN_01819	3e-98	-	-	-	S	-	-	-	polysaccharide biosynthetic process
DHDEBFGN_01820	3.01e-97	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Transcriptional regulator
DHDEBFGN_01821	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
DHDEBFGN_01823	0.0	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
DHDEBFGN_01824	1.99e-182	cas5	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
DHDEBFGN_01825	1.02e-92	csd1	-	-	M	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
DHDEBFGN_01826	1.72e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DHDEBFGN_01827	2.83e-206	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
DHDEBFGN_01828	1.4e-234	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
DHDEBFGN_01829	3.87e-50	-	-	-	S	-	-	-	Cytochrome B5
DHDEBFGN_01833	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DHDEBFGN_01834	1.89e-123	-	-	-	K	-	-	-	transcriptional regulator
DHDEBFGN_01835	1.64e-94	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
DHDEBFGN_01836	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
DHDEBFGN_01837	3.11e-71	-	-	-	S	-	-	-	MazG-like family
DHDEBFGN_01838	5.35e-139	-	-	-	I	-	-	-	PAP2 superfamily
DHDEBFGN_01839	1.74e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
DHDEBFGN_01840	7.4e-126	-	-	-	-	-	-	-	-
DHDEBFGN_01841	8.51e-286	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
DHDEBFGN_01842	5.58e-219	-	-	-	V	-	-	-	Beta-lactamase enzyme family
DHDEBFGN_01843	0.0	potE	-	-	E	-	-	-	Amino Acid
DHDEBFGN_01845	2.74e-144	-	-	-	-	-	-	-	-
DHDEBFGN_01846	1.58e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
DHDEBFGN_01847	1.71e-211	-	-	-	K	-	-	-	LysR substrate binding domain
DHDEBFGN_01848	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
DHDEBFGN_01849	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
DHDEBFGN_01850	2.75e-248	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
DHDEBFGN_01851	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
DHDEBFGN_01852	1.87e-139	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DHDEBFGN_01853	8.63e-58	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DHDEBFGN_01854	6.84e-100	mleR	-	-	K	-	-	-	LysR family
DHDEBFGN_01855	7.62e-290	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
DHDEBFGN_01856	4.41e-233	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
DHDEBFGN_01857	1.76e-96	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DHDEBFGN_01858	1.03e-07	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DHDEBFGN_01859	3.78e-282	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DHDEBFGN_01860	1.1e-275	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DHDEBFGN_01861	4.87e-212	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
DHDEBFGN_01862	1.06e-312	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
DHDEBFGN_01863	7.07e-222	citR	-	-	K	-	-	-	sugar-binding domain protein
DHDEBFGN_01864	1.47e-267	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
DHDEBFGN_01865	3.95e-251	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DHDEBFGN_01866	3.36e-61	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
DHDEBFGN_01867	7.54e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
DHDEBFGN_01868	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
DHDEBFGN_01869	0.0	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
DHDEBFGN_01870	7.76e-188	-	-	-	I	-	-	-	Alpha/beta hydrolase family
DHDEBFGN_01871	7.53e-208	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
DHDEBFGN_01872	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
DHDEBFGN_01873	1.2e-155	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
DHDEBFGN_01874	1.92e-241	-	-	-	I	-	-	-	Alpha beta
DHDEBFGN_01875	2.87e-138	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
DHDEBFGN_01876	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DHDEBFGN_01878	2.46e-216	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DHDEBFGN_01879	1.74e-187	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
DHDEBFGN_01880	4.73e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
DHDEBFGN_01881	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
DHDEBFGN_01882	3.98e-96	-	-	-	K	-	-	-	MerR HTH family regulatory protein
DHDEBFGN_01883	1.15e-77	-	-	-	-	-	-	-	-
DHDEBFGN_01884	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DHDEBFGN_01885	4.6e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DHDEBFGN_01886	4.75e-28	elaA	-	-	S	ko:K02348	-	ko00000	acyltransferase COG2153
DHDEBFGN_01887	2.49e-110	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
DHDEBFGN_01888	7.81e-141	-	-	-	S	-	-	-	VIT family
DHDEBFGN_01889	8.48e-147	-	-	-	S	-	-	-	membrane
DHDEBFGN_01890	1.89e-204	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
DHDEBFGN_01891	2.51e-158	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
DHDEBFGN_01892	1.26e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
DHDEBFGN_01893	5.57e-103	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DHDEBFGN_01894	1.93e-270	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
DHDEBFGN_01896	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
DHDEBFGN_01897	8.92e-160	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
DHDEBFGN_01898	8.89e-136	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
DHDEBFGN_01899	7.16e-281	-	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
DHDEBFGN_01900	5.97e-27	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
DHDEBFGN_01901	2.85e-239	-	-	-	L	-	-	-	PFAM Integrase catalytic region
DHDEBFGN_01902	7.45e-92	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DHDEBFGN_01903	1.07e-73	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
DHDEBFGN_01904	1.98e-50	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
DHDEBFGN_01905	1.57e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
DHDEBFGN_01906	3.77e-276	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
DHDEBFGN_01907	1.88e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
DHDEBFGN_01908	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
DHDEBFGN_01909	3.27e-148	-	-	-	-	-	-	-	-
DHDEBFGN_01910	1.09e-299	-	-	-	G	-	-	-	Polysaccharide deacetylase
DHDEBFGN_01911	3.05e-08	-	-	-	-	-	-	-	-
DHDEBFGN_01913	9.2e-59	-	-	-	-	-	-	-	-
DHDEBFGN_01916	6.31e-45	-	-	-	-	-	-	-	-
DHDEBFGN_01917	9.36e-110	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
DHDEBFGN_01918	1.68e-107	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
DHDEBFGN_01919	8.27e-80	-	-	-	K	-	-	-	Transcriptional regulator
DHDEBFGN_01921	7.14e-180	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
DHDEBFGN_01923	2.38e-141	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
DHDEBFGN_01924	9.59e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
DHDEBFGN_01925	1.01e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DHDEBFGN_01926	9.43e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
DHDEBFGN_01927	3.19e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
DHDEBFGN_01928	3.9e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DHDEBFGN_01929	3.72e-204	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
DHDEBFGN_01934	8.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
DHDEBFGN_01935	4.31e-212	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
DHDEBFGN_01936	1.09e-227	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
DHDEBFGN_01937	3.43e-60	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
DHDEBFGN_01938	3.48e-90	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
DHDEBFGN_01939	1.22e-180	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
DHDEBFGN_01940	1.11e-121	-	-	-	M	-	-	-	PFAM NLP P60 protein
DHDEBFGN_01941	1.01e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
DHDEBFGN_01942	6.95e-182	-	-	-	-	-	-	-	-
DHDEBFGN_01943	5.94e-238	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
DHDEBFGN_01944	1.08e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
DHDEBFGN_01945	4.62e-92	-	-	-	-	-	-	-	-
DHDEBFGN_01946	5.99e-67	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DHDEBFGN_01947	4.14e-198	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
DHDEBFGN_01948	1.75e-193	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DHDEBFGN_01949	3.89e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
DHDEBFGN_01950	2.65e-140	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DHDEBFGN_01951	4.3e-188	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
DHDEBFGN_01952	3.39e-121	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
DHDEBFGN_01953	2.17e-285	-	-	-	P	-	-	-	Chloride transporter, ClC family
DHDEBFGN_01954	1.66e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DHDEBFGN_01955	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DHDEBFGN_01956	2.23e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
DHDEBFGN_01957	3.2e-211	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DHDEBFGN_01958	3.99e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
DHDEBFGN_01959	4.97e-97	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DHDEBFGN_01960	1.06e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
DHDEBFGN_01961	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DHDEBFGN_01962	1.7e-300	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DHDEBFGN_01963	3.41e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
DHDEBFGN_01964	1.11e-68	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
DHDEBFGN_01965	8.89e-226	-	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	queuine tRNA-ribosyltransferase activity
DHDEBFGN_01966	1.03e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DHDEBFGN_01967	3.58e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DHDEBFGN_01968	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DHDEBFGN_01969	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DHDEBFGN_01970	1.77e-302	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
DHDEBFGN_01971	2.26e-244	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DHDEBFGN_01972	1.62e-293	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
DHDEBFGN_01973	1.79e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DHDEBFGN_01974	1.64e-151	-	-	-	S	-	-	-	Helix-turn-helix domain
DHDEBFGN_01975	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
DHDEBFGN_01976	1.1e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
DHDEBFGN_01977	1.65e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
DHDEBFGN_01978	4.86e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_01979	3.81e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
DHDEBFGN_01980	9.04e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
DHDEBFGN_01981	1.37e-187	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
DHDEBFGN_01982	1.34e-232	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
DHDEBFGN_01983	5.3e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
DHDEBFGN_01984	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
DHDEBFGN_01985	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DHDEBFGN_01986	1.27e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DHDEBFGN_01989	4.58e-82	-	-	-	K	-	-	-	Transcriptional regulator
DHDEBFGN_01990	2.21e-131	cadD	-	-	P	-	-	-	Cadmium resistance transporter
DHDEBFGN_01991	9.03e-17	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
DHDEBFGN_02008	2.21e-144	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DHDEBFGN_02009	8.34e-101	-	-	-	-	-	-	-	-
DHDEBFGN_02010	2.18e-106	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DHDEBFGN_02011	4.37e-106	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
DHDEBFGN_02012	2.65e-54	-	-	-	S	-	-	-	Bacteriophage abortive infection AbiH
DHDEBFGN_02014	5.17e-100	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
DHDEBFGN_02015	2.21e-114	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
DHDEBFGN_02016	8.54e-63	-	-	-	L	-	-	-	Helix-turn-helix domain
DHDEBFGN_02020	3.54e-99	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DHDEBFGN_02021	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
DHDEBFGN_02022	5.57e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
DHDEBFGN_02023	9.56e-196	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
DHDEBFGN_02025	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DHDEBFGN_02026	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
DHDEBFGN_02027	5.35e-90	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DHDEBFGN_02028	3.59e-10	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
DHDEBFGN_02029	2.16e-201	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
DHDEBFGN_02030	3.99e-15	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
DHDEBFGN_02031	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
DHDEBFGN_02032	4.13e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
DHDEBFGN_02033	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DHDEBFGN_02034	4.59e-133	-	-	-	K	-	-	-	Transcriptional regulator
DHDEBFGN_02035	5.02e-31	XK27_06785	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
DHDEBFGN_02036	1.39e-185	-	-	-	M	ko:K02004	-	ko00000,ko00002,ko02000	Membrane
DHDEBFGN_02037	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
DHDEBFGN_02038	8.31e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DHDEBFGN_02039	7.31e-89	-	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DHDEBFGN_02040	2.52e-66	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
DHDEBFGN_02041	5.02e-88	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
DHDEBFGN_02042	7.42e-07	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
DHDEBFGN_02043	6.28e-221	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
DHDEBFGN_02044	6.7e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
DHDEBFGN_02045	4.09e-136	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
DHDEBFGN_02046	5.61e-110	-	-	-	-	-	-	-	-
DHDEBFGN_02047	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
DHDEBFGN_02048	0.0	-	1.7.2.5	-	P	ko:K04561	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Cytochrome C and Quinol oxidase polypeptide I
DHDEBFGN_02049	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
DHDEBFGN_02050	5.75e-147	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
DHDEBFGN_02051	1.65e-101	dltr	-	-	K	-	-	-	response regulator
DHDEBFGN_02052	8.4e-164	sptS	-	-	T	-	-	-	Histidine kinase
DHDEBFGN_02053	1.61e-223	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
DHDEBFGN_02054	3.4e-136	-	-	-	K	-	-	-	acetyltransferase
DHDEBFGN_02055	1.05e-174	-	-	-	IQ	-	-	-	dehydrogenase reductase
DHDEBFGN_02056	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DHDEBFGN_02057	5.52e-204	-	-	-	EG	-	-	-	EamA-like transporter family
DHDEBFGN_02058	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
DHDEBFGN_02059	1.45e-152	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
DHDEBFGN_02060	1.92e-155	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
DHDEBFGN_02061	2.06e-297	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DHDEBFGN_02062	2.64e-267	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
DHDEBFGN_02063	1.45e-172	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
DHDEBFGN_02064	0.0	-	-	-	E	-	-	-	amino acid