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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HCDAONAO_00001	8.95e-315	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCDAONAO_00002	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCDAONAO_00003	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HCDAONAO_00004	1.03e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCDAONAO_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCDAONAO_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCDAONAO_00007	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HCDAONAO_00008	4.91e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HCDAONAO_00009	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCDAONAO_00010	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HCDAONAO_00011	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HCDAONAO_00012	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HCDAONAO_00013	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HCDAONAO_00014	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCDAONAO_00015	7.65e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCDAONAO_00016	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HCDAONAO_00017	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HCDAONAO_00018	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HCDAONAO_00019	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HCDAONAO_00020	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HCDAONAO_00021	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HCDAONAO_00022	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HCDAONAO_00024	2.4e-183	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HCDAONAO_00025	2.22e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HCDAONAO_00026	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HCDAONAO_00027	2.54e-43	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HCDAONAO_00028	5.31e-28	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HCDAONAO_00029	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HCDAONAO_00030	2.54e-50	-	-	-	-	-	-	-	-
HCDAONAO_00032	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HCDAONAO_00033	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCDAONAO_00034	1.44e-312	yycH	-	-	S	-	-	-	YycH protein
HCDAONAO_00035	3.79e-190	yycI	-	-	S	-	-	-	YycH protein
HCDAONAO_00036	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HCDAONAO_00037	3.02e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HCDAONAO_00038	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCDAONAO_00039	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCDAONAO_00040	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HCDAONAO_00041	1.2e-214	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HCDAONAO_00042	4.91e-156	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HCDAONAO_00043	6.59e-17	pnb	-	-	C	-	-	-	nitroreductase
HCDAONAO_00044	6.55e-85	pnb	-	-	C	-	-	-	nitroreductase
HCDAONAO_00045	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HCDAONAO_00046	1.83e-149	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HCDAONAO_00047	0.0	-	-	-	C	-	-	-	FMN_bind
HCDAONAO_00048	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HCDAONAO_00049	1.7e-203	-	-	-	K	-	-	-	LysR family
HCDAONAO_00050	5.88e-94	-	-	-	C	-	-	-	FMN binding
HCDAONAO_00051	1.02e-94	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCDAONAO_00052	1.17e-210	-	-	-	S	-	-	-	KR domain
HCDAONAO_00053	2.73e-202	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HCDAONAO_00054	1.46e-156	ydgI	-	-	C	-	-	-	Nitroreductase family
HCDAONAO_00055	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HCDAONAO_00056	3.83e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HCDAONAO_00057	1.48e-149	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCDAONAO_00058	6.19e-284	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HCDAONAO_00059	7.98e-65	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCDAONAO_00060	2.52e-179	-	-	-	S	-	-	-	Putative threonine/serine exporter
HCDAONAO_00061	6.86e-175	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HCDAONAO_00062	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HCDAONAO_00063	1.65e-106	-	-	-	S	-	-	-	ASCH
HCDAONAO_00064	1.77e-164	-	-	-	F	-	-	-	glutamine amidotransferase
HCDAONAO_00065	3.78e-33	-	-	-	K	-	-	-	WYL domain
HCDAONAO_00066	1.47e-72	-	-	-	K	-	-	-	WYL domain
HCDAONAO_00067	6.65e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCDAONAO_00068	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HCDAONAO_00069	8.07e-164	-	-	-	S	-	-	-	Protein of unknown function
HCDAONAO_00070	2.12e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HCDAONAO_00071	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HCDAONAO_00072	1.15e-161	-	-	-	S	-	-	-	DJ-1/PfpI family
HCDAONAO_00073	1.98e-233	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HCDAONAO_00074	7.81e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HCDAONAO_00075	2.23e-297	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HCDAONAO_00076	1.73e-217	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HCDAONAO_00077	5.24e-179	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HCDAONAO_00078	2.38e-99	-	-	-	-	-	-	-	-
HCDAONAO_00079	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HCDAONAO_00080	5.67e-179	-	-	-	-	-	-	-	-
HCDAONAO_00081	4.07e-05	-	-	-	-	-	-	-	-
HCDAONAO_00082	7.41e-182	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HCDAONAO_00083	1.67e-54	-	-	-	-	-	-	-	-
HCDAONAO_00084	3.02e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCDAONAO_00085	6.89e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HCDAONAO_00086	1.29e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HCDAONAO_00087	1.45e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HCDAONAO_00088	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HCDAONAO_00089	1.86e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HCDAONAO_00090	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HCDAONAO_00091	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HCDAONAO_00092	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HCDAONAO_00093	3.03e-192	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HCDAONAO_00094	3.94e-224	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HCDAONAO_00095	1.79e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HCDAONAO_00096	4.13e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HCDAONAO_00097	2.68e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HCDAONAO_00098	1.69e-260	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HCDAONAO_00099	1.02e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HCDAONAO_00100	0.0	-	-	-	L	-	-	-	HIRAN domain
HCDAONAO_00101	3.55e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HCDAONAO_00102	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HCDAONAO_00103	3.13e-160	-	-	-	-	-	-	-	-
HCDAONAO_00104	5.08e-192	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HCDAONAO_00105	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HCDAONAO_00106	8.08e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
HCDAONAO_00107	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HCDAONAO_00108	5.13e-144	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HCDAONAO_00109	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_00110	3.28e-95	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HCDAONAO_00111	2.19e-289	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HCDAONAO_00112	2.21e-65	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HCDAONAO_00113	9.31e-273	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HCDAONAO_00115	3.07e-204	morA	-	-	S	-	-	-	reductase
HCDAONAO_00116	3.34e-212	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HCDAONAO_00117	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HCDAONAO_00118	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HCDAONAO_00119	5.05e-114	-	-	-	-	-	-	-	-
HCDAONAO_00120	0.0	-	-	-	-	-	-	-	-
HCDAONAO_00121	2.17e-266	-	-	-	C	-	-	-	Oxidoreductase
HCDAONAO_00122	7.71e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HCDAONAO_00123	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_00124	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HCDAONAO_00126	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HCDAONAO_00127	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HCDAONAO_00128	3.01e-180	-	-	-	-	-	-	-	-
HCDAONAO_00129	1.1e-191	-	-	-	-	-	-	-	-
HCDAONAO_00130	3.37e-115	-	-	-	-	-	-	-	-
HCDAONAO_00131	7.14e-185	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HCDAONAO_00132	6.03e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HCDAONAO_00133	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HCDAONAO_00134	8.03e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HCDAONAO_00135	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HCDAONAO_00136	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HCDAONAO_00138	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCDAONAO_00139	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HCDAONAO_00140	2.24e-238	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HCDAONAO_00141	3.9e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HCDAONAO_00142	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HCDAONAO_00143	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HCDAONAO_00144	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HCDAONAO_00145	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HCDAONAO_00146	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HCDAONAO_00147	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCDAONAO_00148	1.52e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCDAONAO_00149	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCDAONAO_00150	1.01e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HCDAONAO_00151	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HCDAONAO_00152	5.75e-266	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HCDAONAO_00153	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HCDAONAO_00154	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HCDAONAO_00155	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HCDAONAO_00156	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HCDAONAO_00157	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HCDAONAO_00158	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HCDAONAO_00159	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HCDAONAO_00160	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HCDAONAO_00161	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HCDAONAO_00162	1.16e-210	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HCDAONAO_00163	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HCDAONAO_00164	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HCDAONAO_00165	1.72e-212	mleR	-	-	K	-	-	-	LysR substrate binding domain
HCDAONAO_00166	0.0	-	-	-	M	-	-	-	domain protein
HCDAONAO_00168	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HCDAONAO_00169	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HCDAONAO_00170	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HCDAONAO_00171	5.35e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HCDAONAO_00172	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCDAONAO_00173	7.18e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HCDAONAO_00174	9.51e-148	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HCDAONAO_00175	2.49e-229	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HCDAONAO_00176	6.33e-46	-	-	-	-	-	-	-	-
HCDAONAO_00177	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HCDAONAO_00178	1.46e-206	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HCDAONAO_00179	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCDAONAO_00180	3.81e-18	-	-	-	-	-	-	-	-
HCDAONAO_00181	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCDAONAO_00182	2.31e-73	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCDAONAO_00183	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HCDAONAO_00184	2.45e-177	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCDAONAO_00185	8.3e-87	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HCDAONAO_00186	1.5e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HCDAONAO_00187	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HCDAONAO_00188	2.02e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HCDAONAO_00189	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HCDAONAO_00190	5.3e-202	dkgB	-	-	S	-	-	-	reductase
HCDAONAO_00191	1.28e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCDAONAO_00192	1.2e-91	-	-	-	-	-	-	-	-
HCDAONAO_00193	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
HCDAONAO_00194	2.69e-226	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HCDAONAO_00195	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCDAONAO_00197	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCDAONAO_00198	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HCDAONAO_00199	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HCDAONAO_00200	2.17e-102	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCDAONAO_00201	1.06e-281	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HCDAONAO_00202	1.21e-111	-	-	-	-	-	-	-	-
HCDAONAO_00203	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HCDAONAO_00204	4.17e-67	-	-	-	-	-	-	-	-
HCDAONAO_00205	4.99e-125	-	-	-	-	-	-	-	-
HCDAONAO_00206	2.98e-90	-	-	-	-	-	-	-	-
HCDAONAO_00207	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HCDAONAO_00208	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HCDAONAO_00209	1.82e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HCDAONAO_00210	7.42e-125	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HCDAONAO_00211	5.78e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HCDAONAO_00212	1.78e-209	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HCDAONAO_00213	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HCDAONAO_00214	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HCDAONAO_00215	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HCDAONAO_00216	2.21e-56	-	-	-	-	-	-	-	-
HCDAONAO_00217	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HCDAONAO_00218	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HCDAONAO_00219	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HCDAONAO_00220	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HCDAONAO_00221	2.6e-185	-	-	-	-	-	-	-	-
HCDAONAO_00222	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
HCDAONAO_00223	4.5e-303	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
HCDAONAO_00224	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCDAONAO_00225	1.3e-203	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HCDAONAO_00226	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HCDAONAO_00227	1.11e-91	-	-	-	-	-	-	-	-
HCDAONAO_00229	9.12e-31	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HCDAONAO_00230	1.16e-29	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HCDAONAO_00231	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_00232	5.2e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCDAONAO_00233	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HCDAONAO_00234	1.15e-152	-	-	-	-	-	-	-	-
HCDAONAO_00235	2.92e-57	-	-	-	-	-	-	-	-
HCDAONAO_00236	1.55e-55	-	-	-	-	-	-	-	-
HCDAONAO_00237	6.19e-284	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HCDAONAO_00238	2.94e-297	ydiC	-	-	EGP	-	-	-	Major Facilitator
HCDAONAO_00239	8.98e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HCDAONAO_00240	6.56e-90	hpk2	-	-	T	-	-	-	Histidine kinase
HCDAONAO_00241	1.39e-194	hpk2	-	-	T	-	-	-	Histidine kinase
HCDAONAO_00242	1.33e-165	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HCDAONAO_00243	2.42e-65	-	-	-	-	-	-	-	-
HCDAONAO_00244	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HCDAONAO_00245	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCDAONAO_00246	3.35e-75	-	-	-	-	-	-	-	-
HCDAONAO_00247	2.87e-56	-	-	-	-	-	-	-	-
HCDAONAO_00248	1.76e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HCDAONAO_00249	4.16e-108	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HCDAONAO_00250	2.26e-179	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HCDAONAO_00251	1.49e-63	-	-	-	-	-	-	-	-
HCDAONAO_00252	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HCDAONAO_00253	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HCDAONAO_00254	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HCDAONAO_00255	8.31e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HCDAONAO_00256	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HCDAONAO_00257	7.93e-290	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HCDAONAO_00258	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HCDAONAO_00259	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HCDAONAO_00260	2.75e-156	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HCDAONAO_00261	7.98e-80	-	-	-	M	-	-	-	Lysin motif
HCDAONAO_00262	3.73e-99	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HCDAONAO_00263	1.56e-78	-	-	-	L	-	-	-	Transposase DDE domain
HCDAONAO_00264	2.31e-95	-	-	-	M	-	-	-	LysM domain protein
HCDAONAO_00265	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HCDAONAO_00266	4.29e-227	-	-	-	-	-	-	-	-
HCDAONAO_00267	2.8e-169	-	-	-	-	-	-	-	-
HCDAONAO_00268	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HCDAONAO_00269	2.04e-73	-	-	-	-	-	-	-	-
HCDAONAO_00270	9.17e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCDAONAO_00271	1.08e-101	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HCDAONAO_00272	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_00273	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HCDAONAO_00274	2.18e-53	-	-	-	-	-	-	-	-
HCDAONAO_00275	5.3e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCDAONAO_00276	5.58e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCDAONAO_00277	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCDAONAO_00278	5.09e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCDAONAO_00279	4.3e-124	-	-	-	K	-	-	-	Cupin domain
HCDAONAO_00280	1.15e-109	-	-	-	S	-	-	-	ASCH
HCDAONAO_00281	1.88e-111	-	-	-	K	-	-	-	GNAT family
HCDAONAO_00282	2.92e-115	-	-	-	K	-	-	-	acetyltransferase
HCDAONAO_00283	2.06e-30	-	-	-	-	-	-	-	-
HCDAONAO_00284	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HCDAONAO_00285	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCDAONAO_00286	1.08e-243	-	-	-	-	-	-	-	-
HCDAONAO_00287	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HCDAONAO_00288	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HCDAONAO_00290	1.12e-303	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HCDAONAO_00291	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HCDAONAO_00292	2.97e-41	-	-	-	-	-	-	-	-
HCDAONAO_00293	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCDAONAO_00294	6.4e-54	-	-	-	-	-	-	-	-
HCDAONAO_00295	3.62e-122	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HCDAONAO_00296	4.28e-227	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCDAONAO_00297	1.45e-79	-	-	-	S	-	-	-	CHY zinc finger
HCDAONAO_00298	8.69e-143	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HCDAONAO_00299	1.13e-157	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCDAONAO_00300	4.45e-116	metP_2	-	-	U	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCDAONAO_00301	1.14e-186	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCDAONAO_00302	3.43e-281	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCDAONAO_00303	1.57e-280	-	-	-	-	-	-	-	-
HCDAONAO_00304	4.7e-198	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HCDAONAO_00305	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HCDAONAO_00306	3.93e-59	-	-	-	-	-	-	-	-
HCDAONAO_00307	2.39e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HCDAONAO_00308	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HCDAONAO_00309	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HCDAONAO_00310	9e-227	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HCDAONAO_00311	8.95e-60	-	-	-	-	-	-	-	-
HCDAONAO_00312	6.06e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HCDAONAO_00313	6.87e-153	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HCDAONAO_00314	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HCDAONAO_00315	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HCDAONAO_00316	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HCDAONAO_00317	1.61e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HCDAONAO_00318	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HCDAONAO_00319	1.52e-103	-	-	-	-	-	-	-	-
HCDAONAO_00320	1.46e-100	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCDAONAO_00321	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HCDAONAO_00322	2.42e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HCDAONAO_00323	4.06e-102	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HCDAONAO_00324	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCDAONAO_00325	1.1e-229	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_00326	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HCDAONAO_00327	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCDAONAO_00328	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HCDAONAO_00329	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HCDAONAO_00330	0.0	-	-	-	M	-	-	-	domain protein
HCDAONAO_00331	1.01e-51	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HCDAONAO_00332	9.86e-200	is18	-	-	L	-	-	-	Integrase core domain
HCDAONAO_00333	9.15e-41	-	-	-	-	-	-	-	-
HCDAONAO_00334	0.0	-	-	-	L	-	-	-	DNA helicase
HCDAONAO_00335	2.05e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HCDAONAO_00336	8.19e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HCDAONAO_00337	1.56e-165	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HCDAONAO_00338	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCDAONAO_00339	9.68e-34	-	-	-	-	-	-	-	-
HCDAONAO_00340	3.55e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HCDAONAO_00341	1.84e-316	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCDAONAO_00342	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HCDAONAO_00343	2e-208	-	-	-	GK	-	-	-	ROK family
HCDAONAO_00344	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HCDAONAO_00345	5.93e-244	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCDAONAO_00346	2.35e-215	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HCDAONAO_00347	1.32e-288	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HCDAONAO_00348	4.65e-229	-	-	-	-	-	-	-	-
HCDAONAO_00349	2.14e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HCDAONAO_00350	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HCDAONAO_00351	5.43e-91	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HCDAONAO_00352	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCDAONAO_00353	1.49e-272	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HCDAONAO_00354	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HCDAONAO_00355	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HCDAONAO_00356	2.5e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCDAONAO_00357	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HCDAONAO_00358	1.07e-207	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HCDAONAO_00359	1.1e-229	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HCDAONAO_00360	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HCDAONAO_00361	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HCDAONAO_00362	3.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HCDAONAO_00363	3.28e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCDAONAO_00364	2.82e-196	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HCDAONAO_00365	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCDAONAO_00366	1.82e-232	-	-	-	S	-	-	-	DUF218 domain
HCDAONAO_00367	3.53e-178	-	-	-	-	-	-	-	-
HCDAONAO_00368	1.45e-191	yxeH	-	-	S	-	-	-	hydrolase
HCDAONAO_00369	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HCDAONAO_00370	2.46e-197	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HCDAONAO_00371	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HCDAONAO_00372	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HCDAONAO_00373	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCDAONAO_00374	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCDAONAO_00375	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HCDAONAO_00376	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HCDAONAO_00377	1.14e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HCDAONAO_00378	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HCDAONAO_00379	1.15e-35	-	-	-	-	-	-	-	-
HCDAONAO_00380	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCDAONAO_00381	1.26e-305	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HCDAONAO_00382	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HCDAONAO_00383	5.19e-274	-	-	-	J	-	-	-	translation release factor activity
HCDAONAO_00384	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HCDAONAO_00385	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HCDAONAO_00386	4.58e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HCDAONAO_00387	1.84e-189	-	-	-	-	-	-	-	-
HCDAONAO_00388	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCDAONAO_00389	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCDAONAO_00390	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCDAONAO_00391	8.29e-274	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCDAONAO_00392	4.39e-85	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HCDAONAO_00393	1.31e-86	-	-	-	L	-	-	-	Transposase DDE domain
HCDAONAO_00394	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HCDAONAO_00395	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HCDAONAO_00396	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HCDAONAO_00397	3.55e-258	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HCDAONAO_00398	2.09e-243	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HCDAONAO_00399	3.39e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HCDAONAO_00400	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HCDAONAO_00401	1.9e-277	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HCDAONAO_00402	1.07e-240	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCDAONAO_00403	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HCDAONAO_00404	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
HCDAONAO_00405	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HCDAONAO_00406	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HCDAONAO_00407	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCDAONAO_00408	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCDAONAO_00409	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HCDAONAO_00410	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HCDAONAO_00412	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HCDAONAO_00413	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HCDAONAO_00414	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCDAONAO_00415	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HCDAONAO_00416	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCDAONAO_00417	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HCDAONAO_00418	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCDAONAO_00419	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HCDAONAO_00422	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HCDAONAO_00425	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HCDAONAO_00426	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HCDAONAO_00430	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HCDAONAO_00431	1.38e-71	-	-	-	S	-	-	-	Cupin domain
HCDAONAO_00432	5.35e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HCDAONAO_00433	5.32e-246	ysdE	-	-	P	-	-	-	Citrate transporter
HCDAONAO_00434	4.33e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HCDAONAO_00435	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCDAONAO_00436	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCDAONAO_00437	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HCDAONAO_00438	1.14e-176	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HCDAONAO_00439	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCDAONAO_00440	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HCDAONAO_00441	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HCDAONAO_00442	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HCDAONAO_00443	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HCDAONAO_00444	3.76e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HCDAONAO_00445	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HCDAONAO_00446	1.19e-201	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCDAONAO_00448	1e-200	-	-	-	G	-	-	-	Peptidase_C39 like family
HCDAONAO_00449	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HCDAONAO_00450	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HCDAONAO_00451	1.87e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HCDAONAO_00452	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HCDAONAO_00453	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HCDAONAO_00454	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HCDAONAO_00455	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HCDAONAO_00456	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCDAONAO_00457	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HCDAONAO_00458	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HCDAONAO_00459	1.49e-183	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCDAONAO_00460	1.18e-175	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HCDAONAO_00461	1.88e-233	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HCDAONAO_00462	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HCDAONAO_00463	7.04e-226	-	-	-	EG	-	-	-	EamA-like transporter family
HCDAONAO_00464	1.91e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCDAONAO_00465	1.12e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HCDAONAO_00466	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HCDAONAO_00467	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HCDAONAO_00468	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HCDAONAO_00469	3.29e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HCDAONAO_00470	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCDAONAO_00471	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HCDAONAO_00472	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCDAONAO_00473	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HCDAONAO_00474	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HCDAONAO_00475	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCDAONAO_00476	5.87e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HCDAONAO_00477	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HCDAONAO_00478	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HCDAONAO_00479	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCDAONAO_00480	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HCDAONAO_00481	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCDAONAO_00482	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCDAONAO_00483	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCDAONAO_00484	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCDAONAO_00485	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCDAONAO_00486	2.38e-225	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HCDAONAO_00487	2.26e-84	-	-	-	L	-	-	-	nuclease
HCDAONAO_00488	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCDAONAO_00489	5.03e-50	-	-	-	K	-	-	-	Helix-turn-helix domain
HCDAONAO_00490	2.77e-139	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HCDAONAO_00491	1.43e-252	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCDAONAO_00492	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCDAONAO_00493	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HCDAONAO_00494	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HCDAONAO_00495	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCDAONAO_00496	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCDAONAO_00497	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCDAONAO_00498	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCDAONAO_00499	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HCDAONAO_00500	1.28e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCDAONAO_00501	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HCDAONAO_00502	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HCDAONAO_00503	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HCDAONAO_00504	2.64e-213	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCDAONAO_00505	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HCDAONAO_00506	4.06e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HCDAONAO_00507	5.35e-270	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HCDAONAO_00508	2.8e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HCDAONAO_00509	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCDAONAO_00510	6.51e-178	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HCDAONAO_00511	2.68e-176	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HCDAONAO_00512	3.46e-242	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HCDAONAO_00513	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HCDAONAO_00514	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HCDAONAO_00515	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HCDAONAO_00516	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCDAONAO_00517	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HCDAONAO_00518	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HCDAONAO_00519	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HCDAONAO_00520	5.69e-54	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCDAONAO_00521	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCDAONAO_00522	0.0	ydaO	-	-	E	-	-	-	amino acid
HCDAONAO_00523	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HCDAONAO_00524	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HCDAONAO_00525	2.14e-148	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HCDAONAO_00526	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HCDAONAO_00527	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HCDAONAO_00528	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCDAONAO_00529	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCDAONAO_00530	3.41e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCDAONAO_00531	4.29e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HCDAONAO_00532	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HCDAONAO_00533	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCDAONAO_00534	5.67e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HCDAONAO_00535	4.48e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HCDAONAO_00536	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HCDAONAO_00537	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCDAONAO_00538	2.69e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCDAONAO_00539	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HCDAONAO_00540	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HCDAONAO_00541	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HCDAONAO_00542	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HCDAONAO_00543	6.26e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCDAONAO_00544	1.98e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HCDAONAO_00545	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HCDAONAO_00546	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HCDAONAO_00547	0.0	nox	-	-	C	-	-	-	NADH oxidase
HCDAONAO_00548	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCDAONAO_00549	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HCDAONAO_00550	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HCDAONAO_00551	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HCDAONAO_00552	2.4e-169	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HCDAONAO_00553	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCDAONAO_00554	7.69e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HCDAONAO_00555	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HCDAONAO_00556	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HCDAONAO_00557	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCDAONAO_00558	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCDAONAO_00559	2.59e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCDAONAO_00560	7.49e-300	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCDAONAO_00561	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HCDAONAO_00562	6.07e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HCDAONAO_00563	2.83e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HCDAONAO_00564	4.56e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HCDAONAO_00565	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HCDAONAO_00566	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HCDAONAO_00567	1.55e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCDAONAO_00568	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCDAONAO_00570	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HCDAONAO_00571	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HCDAONAO_00572	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCDAONAO_00573	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HCDAONAO_00574	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCDAONAO_00575	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCDAONAO_00576	2.42e-169	-	-	-	-	-	-	-	-
HCDAONAO_00577	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HCDAONAO_00578	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HCDAONAO_00579	6.62e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HCDAONAO_00580	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCDAONAO_00581	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HCDAONAO_00582	1.05e-254	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HCDAONAO_00583	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HCDAONAO_00584	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCDAONAO_00585	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_00586	5.62e-137	-	-	-	-	-	-	-	-
HCDAONAO_00587	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HCDAONAO_00588	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCDAONAO_00589	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HCDAONAO_00590	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HCDAONAO_00591	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HCDAONAO_00592	1.98e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HCDAONAO_00593	1.03e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HCDAONAO_00594	8.14e-209	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HCDAONAO_00595	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HCDAONAO_00596	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HCDAONAO_00597	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HCDAONAO_00598	5.68e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HCDAONAO_00599	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCDAONAO_00600	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HCDAONAO_00601	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCDAONAO_00602	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCDAONAO_00603	5.44e-159	-	-	-	T	-	-	-	EAL domain
HCDAONAO_00604	3.14e-187	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HCDAONAO_00605	4.22e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCDAONAO_00606	3.43e-262	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HCDAONAO_00607	3.38e-70	-	-	-	-	-	-	-	-
HCDAONAO_00608	2.49e-95	-	-	-	-	-	-	-	-
HCDAONAO_00609	1.17e-167	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HCDAONAO_00610	3.51e-197	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HCDAONAO_00611	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCDAONAO_00612	6.37e-186	-	-	-	-	-	-	-	-
HCDAONAO_00614	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HCDAONAO_00615	3.88e-46	-	-	-	-	-	-	-	-
HCDAONAO_00616	2.08e-117	-	-	-	V	-	-	-	VanZ like family
HCDAONAO_00617	1.06e-314	-	-	-	EGP	-	-	-	Major Facilitator
HCDAONAO_00618	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HCDAONAO_00619	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HCDAONAO_00620	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HCDAONAO_00621	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HCDAONAO_00622	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_00623	1.36e-27	-	-	-	-	-	-	-	-
HCDAONAO_00624	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HCDAONAO_00625	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HCDAONAO_00626	2.71e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HCDAONAO_00627	1.11e-290	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HCDAONAO_00628	8.95e-96	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HCDAONAO_00629	7.44e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HCDAONAO_00630	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCDAONAO_00631	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HCDAONAO_00632	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HCDAONAO_00633	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
HCDAONAO_00634	1.09e-60	-	-	-	-	-	-	-	-
HCDAONAO_00635	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HCDAONAO_00636	6.12e-115	-	-	-	-	-	-	-	-
HCDAONAO_00637	3.03e-190	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HCDAONAO_00638	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
HCDAONAO_00639	1.48e-27	-	-	-	-	-	-	-	-
HCDAONAO_00640	7.32e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HCDAONAO_00641	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HCDAONAO_00642	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HCDAONAO_00643	1.01e-188	-	-	-	-	-	-	-	-
HCDAONAO_00644	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HCDAONAO_00645	3.21e-268	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCDAONAO_00646	1.03e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCDAONAO_00647	1.28e-54	-	-	-	-	-	-	-	-
HCDAONAO_00649	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_00650	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HCDAONAO_00651	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCDAONAO_00652	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCDAONAO_00653	2.99e-109	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCDAONAO_00654	1.34e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HCDAONAO_00655	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HCDAONAO_00656	1.57e-182	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HCDAONAO_00657	1.5e-315	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HCDAONAO_00658	3.1e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HCDAONAO_00659	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HCDAONAO_00660	1.03e-91	-	-	-	K	-	-	-	MarR family
HCDAONAO_00661	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCDAONAO_00662	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HCDAONAO_00663	2.11e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCDAONAO_00664	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCDAONAO_00665	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
HCDAONAO_00666	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HCDAONAO_00667	1.61e-36	-	-	-	-	-	-	-	-
HCDAONAO_00668	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HCDAONAO_00669	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HCDAONAO_00670	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HCDAONAO_00671	1.19e-226	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HCDAONAO_00672	1.07e-203	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HCDAONAO_00673	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HCDAONAO_00674	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HCDAONAO_00675	8.3e-87	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HCDAONAO_00676	2.45e-177	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCDAONAO_00677	1.05e-143	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HCDAONAO_00678	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HCDAONAO_00679	3.59e-212	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HCDAONAO_00680	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HCDAONAO_00681	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HCDAONAO_00682	2.97e-69	-	-	-	-	-	-	-	-
HCDAONAO_00683	3.03e-190	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HCDAONAO_00684	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
HCDAONAO_00685	0.0	-	-	-	L	-	-	-	AAA domain
HCDAONAO_00686	8.2e-149	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HCDAONAO_00687	6e-39	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HCDAONAO_00688	9.71e-231	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HCDAONAO_00689	1.59e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HCDAONAO_00690	2.36e-121	-	-	-	D	-	-	-	nuclear chromosome segregation
HCDAONAO_00691	9.62e-12	-	-	-	-	-	-	-	-
HCDAONAO_00692	1.43e-66	-	-	-	-	-	-	-	-
HCDAONAO_00693	5.53e-205	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HCDAONAO_00694	6.35e-69	-	-	-	-	-	-	-	-
HCDAONAO_00695	2.09e-60	-	-	-	S	-	-	-	MORN repeat
HCDAONAO_00696	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HCDAONAO_00697	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HCDAONAO_00698	1.95e-116	-	-	-	-	-	-	-	-
HCDAONAO_00699	5.74e-32	-	-	-	-	-	-	-	-
HCDAONAO_00700	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HCDAONAO_00701	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HCDAONAO_00702	1.95e-114	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HCDAONAO_00703	4.05e-211	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCDAONAO_00704	2.36e-191	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HCDAONAO_00705	3.88e-207	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HCDAONAO_00706	5.21e-62	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HCDAONAO_00707	2.19e-131	-	-	-	G	-	-	-	Glycogen debranching enzyme
HCDAONAO_00708	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HCDAONAO_00709	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HCDAONAO_00710	3.37e-60	-	-	-	S	-	-	-	MazG-like family
HCDAONAO_00711	3.83e-116	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HCDAONAO_00712	0.0	-	-	-	M	-	-	-	MucBP domain
HCDAONAO_00713	1.42e-08	-	-	-	-	-	-	-	-
HCDAONAO_00714	3.49e-113	-	-	-	S	-	-	-	AAA domain
HCDAONAO_00715	2.14e-179	-	-	-	K	-	-	-	sequence-specific DNA binding
HCDAONAO_00716	4.44e-123	-	-	-	K	-	-	-	Helix-turn-helix domain
HCDAONAO_00717	5.36e-218	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_00718	0.0	-	-	-	C	-	-	-	FMN_bind
HCDAONAO_00720	2.39e-103	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_00721	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCDAONAO_00722	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HCDAONAO_00723	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HCDAONAO_00724	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCDAONAO_00725	4.42e-289	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HCDAONAO_00726	9.05e-55	-	-	-	-	-	-	-	-
HCDAONAO_00727	1.53e-42	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HCDAONAO_00728	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HCDAONAO_00729	9.54e-209	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HCDAONAO_00730	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HCDAONAO_00731	3.4e-178	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HCDAONAO_00732	5.55e-244	-	-	-	-	-	-	-	-
HCDAONAO_00733	3.28e-278	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HCDAONAO_00734	4.18e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HCDAONAO_00735	3.36e-132	-	-	-	K	-	-	-	FR47-like protein
HCDAONAO_00736	1.24e-155	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HCDAONAO_00737	1.36e-63	-	-	-	-	-	-	-	-
HCDAONAO_00738	1.72e-245	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCDAONAO_00739	0.0	xylP2	-	-	G	-	-	-	symporter
HCDAONAO_00740	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCDAONAO_00741	1.2e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HCDAONAO_00742	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HCDAONAO_00743	3.43e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HCDAONAO_00744	1.66e-154	azlC	-	-	E	-	-	-	branched-chain amino acid
HCDAONAO_00745	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HCDAONAO_00746	1.46e-170	-	-	-	-	-	-	-	-
HCDAONAO_00747	3.87e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HCDAONAO_00748	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HCDAONAO_00749	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HCDAONAO_00750	1.36e-77	-	-	-	-	-	-	-	-
HCDAONAO_00751	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HCDAONAO_00752	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HCDAONAO_00753	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HCDAONAO_00754	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HCDAONAO_00755	4.05e-211	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCDAONAO_00756	1.95e-114	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HCDAONAO_00757	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HCDAONAO_00758	4.15e-153	-	-	-	I	-	-	-	phosphatase
HCDAONAO_00759	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCDAONAO_00760	7.14e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HCDAONAO_00761	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_00762	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HCDAONAO_00763	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HCDAONAO_00764	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HCDAONAO_00765	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HCDAONAO_00766	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCDAONAO_00774	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HCDAONAO_00775	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCDAONAO_00776	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCDAONAO_00777	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCDAONAO_00778	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCDAONAO_00779	2.57e-150	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HCDAONAO_00780	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCDAONAO_00781	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCDAONAO_00782	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCDAONAO_00783	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HCDAONAO_00784	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCDAONAO_00785	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HCDAONAO_00786	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCDAONAO_00787	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCDAONAO_00788	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCDAONAO_00789	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCDAONAO_00790	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCDAONAO_00791	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCDAONAO_00792	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HCDAONAO_00793	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCDAONAO_00794	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCDAONAO_00795	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCDAONAO_00796	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCDAONAO_00797	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCDAONAO_00798	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCDAONAO_00799	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCDAONAO_00800	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCDAONAO_00801	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HCDAONAO_00802	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HCDAONAO_00803	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCDAONAO_00804	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCDAONAO_00805	1.19e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCDAONAO_00806	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCDAONAO_00807	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCDAONAO_00808	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCDAONAO_00809	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HCDAONAO_00810	2.4e-232	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HCDAONAO_00811	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HCDAONAO_00812	5.37e-112	-	-	-	S	-	-	-	NusG domain II
HCDAONAO_00813	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HCDAONAO_00814	1.51e-86	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HCDAONAO_00815	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HCDAONAO_00816	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCDAONAO_00817	2.31e-196	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCDAONAO_00818	2.85e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCDAONAO_00819	2.49e-186	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCDAONAO_00820	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCDAONAO_00821	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCDAONAO_00822	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HCDAONAO_00823	7e-209	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HCDAONAO_00824	1.17e-233	-	-	-	S	-	-	-	Membrane
HCDAONAO_00825	9.09e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HCDAONAO_00826	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCDAONAO_00827	4.06e-212	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCDAONAO_00828	4.68e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HCDAONAO_00829	2.88e-250	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HCDAONAO_00831	4.43e-278	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HCDAONAO_00832	1.24e-68	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HCDAONAO_00833	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HCDAONAO_00834	1.49e-225	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HCDAONAO_00835	5.2e-253	-	-	-	K	-	-	-	Helix-turn-helix domain
HCDAONAO_00836	3.16e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HCDAONAO_00837	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HCDAONAO_00838	1.76e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HCDAONAO_00839	4.26e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HCDAONAO_00840	1.18e-66	-	-	-	-	-	-	-	-
HCDAONAO_00841	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HCDAONAO_00842	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HCDAONAO_00843	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HCDAONAO_00844	1.11e-263	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HCDAONAO_00845	1.77e-240	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HCDAONAO_00846	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HCDAONAO_00847	9.11e-208	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HCDAONAO_00848	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HCDAONAO_00849	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCDAONAO_00850	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HCDAONAO_00851	8.08e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HCDAONAO_00852	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HCDAONAO_00853	2.65e-214	mleR	-	-	K	-	-	-	LysR family
HCDAONAO_00854	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HCDAONAO_00855	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HCDAONAO_00856	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HCDAONAO_00857	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HCDAONAO_00858	6.07e-33	-	-	-	-	-	-	-	-
HCDAONAO_00859	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HCDAONAO_00860	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HCDAONAO_00861	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HCDAONAO_00862	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HCDAONAO_00863	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HCDAONAO_00864	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HCDAONAO_00865	2.53e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HCDAONAO_00866	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HCDAONAO_00867	7.78e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HCDAONAO_00868	3.41e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HCDAONAO_00869	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCDAONAO_00870	1.61e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HCDAONAO_00871	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HCDAONAO_00872	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HCDAONAO_00873	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCDAONAO_00874	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
HCDAONAO_00875	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCDAONAO_00876	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCDAONAO_00877	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCDAONAO_00878	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HCDAONAO_00879	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCDAONAO_00880	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCDAONAO_00881	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HCDAONAO_00882	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCDAONAO_00883	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCDAONAO_00884	1.88e-194	gntR	-	-	K	-	-	-	rpiR family
HCDAONAO_00885	1.83e-184	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HCDAONAO_00886	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HCDAONAO_00887	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HCDAONAO_00888	1.59e-244	mocA	-	-	S	-	-	-	Oxidoreductase
HCDAONAO_00889	9.46e-315	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HCDAONAO_00891	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HCDAONAO_00892	6.35e-313	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCDAONAO_00893	1.93e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCDAONAO_00895	7.62e-97	-	-	-	-	-	-	-	-
HCDAONAO_00896	2.9e-139	-	-	-	-	-	-	-	-
HCDAONAO_00897	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HCDAONAO_00898	1.75e-276	pbpX	-	-	V	-	-	-	Beta-lactamase
HCDAONAO_00899	4.55e-265	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCDAONAO_00900	1.01e-199	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HCDAONAO_00901	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HCDAONAO_00902	6.08e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HCDAONAO_00904	1.2e-200	is18	-	-	L	-	-	-	Integrase core domain
HCDAONAO_00905	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HCDAONAO_00906	9.02e-70	-	-	-	-	-	-	-	-
HCDAONAO_00907	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HCDAONAO_00908	1.95e-41	-	-	-	-	-	-	-	-
HCDAONAO_00909	1.35e-34	-	-	-	-	-	-	-	-
HCDAONAO_00910	6.87e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HCDAONAO_00911	1.9e-168	-	-	-	-	-	-	-	-
HCDAONAO_00912	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HCDAONAO_00913	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HCDAONAO_00914	1.94e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
HCDAONAO_00915	8.01e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HCDAONAO_00916	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HCDAONAO_00917	1.72e-214	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HCDAONAO_00918	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HCDAONAO_00919	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HCDAONAO_00920	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HCDAONAO_00921	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HCDAONAO_00922	1e-217	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HCDAONAO_00923	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HCDAONAO_00924	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HCDAONAO_00925	0.0	-	-	-	-	-	-	-	-
HCDAONAO_00926	2.12e-252	-	-	-	M	-	-	-	MucBP domain
HCDAONAO_00927	7.84e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HCDAONAO_00928	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HCDAONAO_00929	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HCDAONAO_00930	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HCDAONAO_00931	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCDAONAO_00932	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCDAONAO_00933	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HCDAONAO_00934	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HCDAONAO_00935	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HCDAONAO_00936	2.5e-132	-	-	-	L	-	-	-	Integrase
HCDAONAO_00937	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HCDAONAO_00938	5.6e-41	-	-	-	-	-	-	-	-
HCDAONAO_00939	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HCDAONAO_00940	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCDAONAO_00941	3.32e-284	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HCDAONAO_00942	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HCDAONAO_00943	1.03e-239	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCDAONAO_00944	6.56e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HCDAONAO_00945	5.8e-291	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCDAONAO_00946	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HCDAONAO_00947	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCDAONAO_00950	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HCDAONAO_00962	5.4e-118	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HCDAONAO_00963	7.75e-238	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HCDAONAO_00964	2.07e-123	-	-	-	-	-	-	-	-
HCDAONAO_00965	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCDAONAO_00966	1.03e-200	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HCDAONAO_00967	8.71e-145	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HCDAONAO_00968	6.6e-183	lipA	-	-	I	-	-	-	Carboxylesterase family
HCDAONAO_00969	5.91e-208	-	-	-	P	-	-	-	Major Facilitator Superfamily
HCDAONAO_00970	2.2e-141	-	-	-	GK	-	-	-	ROK family
HCDAONAO_00971	1.61e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HCDAONAO_00972	1.52e-241	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HCDAONAO_00973	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HCDAONAO_00974	3.91e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HCDAONAO_00975	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HCDAONAO_00976	1.93e-156	-	-	-	-	-	-	-	-
HCDAONAO_00977	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCDAONAO_00978	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HCDAONAO_00979	2.37e-250	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HCDAONAO_00980	9.69e-291	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HCDAONAO_00981	7.91e-113	-	-	-	S	-	-	-	Pfam Methyltransferase
HCDAONAO_00982	1.16e-127	-	-	-	S	-	-	-	Pfam Methyltransferase
HCDAONAO_00983	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HCDAONAO_00984	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HCDAONAO_00985	9.32e-40	-	-	-	-	-	-	-	-
HCDAONAO_00986	2.14e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HCDAONAO_00987	1.39e-155	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HCDAONAO_00988	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HCDAONAO_00989	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HCDAONAO_00990	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HCDAONAO_00991	3.03e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCDAONAO_00992	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HCDAONAO_00993	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HCDAONAO_00994	1.24e-259	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HCDAONAO_00995	3.93e-222	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCDAONAO_00996	6.16e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCDAONAO_00997	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCDAONAO_00998	5.45e-162	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HCDAONAO_00999	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HCDAONAO_01000	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCDAONAO_01001	1.53e-166	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HCDAONAO_01002	1.53e-164	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HCDAONAO_01004	6.73e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HCDAONAO_01005	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HCDAONAO_01006	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HCDAONAO_01008	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCDAONAO_01009	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HCDAONAO_01010	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HCDAONAO_01011	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HCDAONAO_01012	1.14e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HCDAONAO_01013	7.83e-140	-	-	-	-	-	-	-	-
HCDAONAO_01014	1.03e-283	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HCDAONAO_01015	5.21e-178	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HCDAONAO_01016	5.37e-74	-	-	-	-	-	-	-	-
HCDAONAO_01017	4.56e-78	-	-	-	-	-	-	-	-
HCDAONAO_01018	1.23e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HCDAONAO_01019	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HCDAONAO_01020	8.82e-119	-	-	-	-	-	-	-	-
HCDAONAO_01021	7.12e-62	-	-	-	-	-	-	-	-
HCDAONAO_01022	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HCDAONAO_01025	4.29e-87	-	-	-	-	-	-	-	-
HCDAONAO_01026	9.03e-16	-	-	-	-	-	-	-	-
HCDAONAO_01027	1.58e-236	-	-	-	-	-	-	-	-
HCDAONAO_01028	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HCDAONAO_01029	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HCDAONAO_01030	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HCDAONAO_01031	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HCDAONAO_01032	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HCDAONAO_01033	7.32e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HCDAONAO_01034	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HCDAONAO_01035	2.44e-223	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HCDAONAO_01036	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HCDAONAO_01037	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HCDAONAO_01038	8.41e-314	dinF	-	-	V	-	-	-	MatE
HCDAONAO_01039	1.79e-42	-	-	-	-	-	-	-	-
HCDAONAO_01042	8.2e-102	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HCDAONAO_01043	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HCDAONAO_01044	4.64e-106	-	-	-	-	-	-	-	-
HCDAONAO_01045	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HCDAONAO_01046	6.25e-138	-	-	-	-	-	-	-	-
HCDAONAO_01047	1.49e-272	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HCDAONAO_01048	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HCDAONAO_01049	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCDAONAO_01050	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HCDAONAO_01051	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HCDAONAO_01052	9.65e-272	arcT	-	-	E	-	-	-	Aminotransferase
HCDAONAO_01053	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HCDAONAO_01054	2.43e-18	-	-	-	-	-	-	-	-
HCDAONAO_01055	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HCDAONAO_01056	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HCDAONAO_01057	4.28e-294	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HCDAONAO_01058	0.0	yhaN	-	-	L	-	-	-	AAA domain
HCDAONAO_01059	3.45e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HCDAONAO_01060	2.73e-278	-	-	-	-	-	-	-	-
HCDAONAO_01061	1.45e-234	-	-	-	M	-	-	-	Peptidase family S41
HCDAONAO_01062	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
HCDAONAO_01063	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HCDAONAO_01064	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HCDAONAO_01065	4.43e-129	-	-	-	-	-	-	-	-
HCDAONAO_01066	4.77e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HCDAONAO_01067	4.68e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HCDAONAO_01068	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCDAONAO_01069	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
HCDAONAO_01070	0.0	-	-	-	S	-	-	-	membrane
HCDAONAO_01071	1.73e-217	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HCDAONAO_01072	2.05e-109	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HCDAONAO_01073	2.08e-284	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HCDAONAO_01074	2.04e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HCDAONAO_01075	1.31e-78	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HCDAONAO_01076	5.62e-137	-	-	-	-	-	-	-	-
HCDAONAO_01077	1.61e-116	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HCDAONAO_01078	9.86e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCDAONAO_01079	2.11e-308	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HCDAONAO_01080	0.0	-	-	-	-	-	-	-	-
HCDAONAO_01081	3.57e-76	-	-	-	-	-	-	-	-
HCDAONAO_01082	3.36e-248	-	-	-	S	-	-	-	Fn3-like domain
HCDAONAO_01083	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HCDAONAO_01084	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HCDAONAO_01085	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCDAONAO_01086	4.76e-73	-	-	-	-	-	-	-	-
HCDAONAO_01087	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HCDAONAO_01088	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_01089	2.73e-283	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HCDAONAO_01090	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HCDAONAO_01091	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCDAONAO_01092	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HCDAONAO_01093	1.45e-145	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCDAONAO_01094	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HCDAONAO_01095	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HCDAONAO_01096	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HCDAONAO_01097	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HCDAONAO_01098	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HCDAONAO_01099	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HCDAONAO_01100	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HCDAONAO_01101	1.57e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCDAONAO_01102	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HCDAONAO_01103	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HCDAONAO_01104	4.52e-241	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HCDAONAO_01105	3.26e-177	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HCDAONAO_01106	2.29e-211	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCDAONAO_01107	6.7e-107	-	-	-	C	-	-	-	Flavodoxin
HCDAONAO_01108	6.26e-92	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HCDAONAO_01109	7.86e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
HCDAONAO_01110	3.92e-248	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HCDAONAO_01111	1.98e-278	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
HCDAONAO_01112	4.08e-78	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HCDAONAO_01113	7.79e-203	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HCDAONAO_01114	9.83e-205	-	-	-	H	-	-	-	geranyltranstransferase activity
HCDAONAO_01115	4.32e-233	-	-	-	-	-	-	-	-
HCDAONAO_01116	3.67e-65	-	-	-	-	-	-	-	-
HCDAONAO_01117	5.46e-152	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HCDAONAO_01118	1.04e-244	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
HCDAONAO_01119	1.48e-98	-	2.7.13.3	-	T	ko:K07683,ko:K10851	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	phosphoenolpyruvate-protein phosphotransferase activity
HCDAONAO_01120	8.84e-52	-	-	-	-	-	-	-	-
HCDAONAO_01121	2.33e-128	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HCDAONAO_01122	7.33e-110	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HCDAONAO_01123	1.66e-116	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HCDAONAO_01124	1.55e-295	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
HCDAONAO_01125	1.34e-108	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HCDAONAO_01126	1.27e-250	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HCDAONAO_01127	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HCDAONAO_01128	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HCDAONAO_01129	5.77e-127	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	Nitrate reductase delta subunit
HCDAONAO_01130	1.89e-158	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
HCDAONAO_01131	8.63e-226	-	-	-	-	-	-	-	-
HCDAONAO_01132	1.8e-96	-	-	-	-	-	-	-	-
HCDAONAO_01133	4.4e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HCDAONAO_01134	3.86e-38	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HCDAONAO_01135	6.99e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HCDAONAO_01136	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCDAONAO_01137	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCDAONAO_01138	9.54e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCDAONAO_01139	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCDAONAO_01140	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HCDAONAO_01141	6.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HCDAONAO_01142	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCDAONAO_01143	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCDAONAO_01144	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HCDAONAO_01145	1.39e-72	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCDAONAO_01146	2.76e-74	-	-	-	-	-	-	-	-
HCDAONAO_01147	1.42e-306	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HCDAONAO_01148	7.09e-252	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HCDAONAO_01149	1.35e-82	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HCDAONAO_01150	1.97e-174	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HCDAONAO_01151	9.51e-317	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HCDAONAO_01152	1.32e-106	-	-	-	-	-	-	-	-
HCDAONAO_01153	2.39e-226	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HCDAONAO_01154	3.3e-126	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HCDAONAO_01155	3.13e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HCDAONAO_01156	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HCDAONAO_01157	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCDAONAO_01158	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HCDAONAO_01159	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCDAONAO_01160	6.65e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
HCDAONAO_01161	3.04e-280	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HCDAONAO_01162	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HCDAONAO_01163	1.77e-123	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HCDAONAO_01164	1.13e-225	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCDAONAO_01165	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCDAONAO_01166	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HCDAONAO_01167	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HCDAONAO_01168	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCDAONAO_01169	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HCDAONAO_01170	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HCDAONAO_01171	9.59e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HCDAONAO_01172	5.08e-122	-	-	-	S	-	-	-	SdpI/YhfL protein family
HCDAONAO_01173	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCDAONAO_01174	2.36e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HCDAONAO_01175	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCDAONAO_01176	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HCDAONAO_01177	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HCDAONAO_01178	1.62e-255	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCDAONAO_01179	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCDAONAO_01180	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HCDAONAO_01181	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HCDAONAO_01182	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCDAONAO_01183	1.32e-143	-	-	-	S	-	-	-	membrane
HCDAONAO_01184	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
HCDAONAO_01185	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HCDAONAO_01186	0.0	-	-	-	S	-	-	-	membrane
HCDAONAO_01187	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HCDAONAO_01188	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HCDAONAO_01189	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HCDAONAO_01190	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HCDAONAO_01191	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HCDAONAO_01192	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HCDAONAO_01193	9.39e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HCDAONAO_01194	6.68e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HCDAONAO_01195	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HCDAONAO_01196	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HCDAONAO_01197	2.29e-225	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCDAONAO_01198	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HCDAONAO_01199	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HCDAONAO_01200	1.77e-205	-	-	-	-	-	-	-	-
HCDAONAO_01201	1.34e-232	-	-	-	-	-	-	-	-
HCDAONAO_01202	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
HCDAONAO_01203	3.11e-73	-	-	-	-	-	-	-	-
HCDAONAO_01204	2.97e-41	-	-	-	-	-	-	-	-
HCDAONAO_01207	9.81e-27	-	-	-	-	-	-	-	-
HCDAONAO_01208	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_01209	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HCDAONAO_01210	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HCDAONAO_01211	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HCDAONAO_01212	3.49e-248	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HCDAONAO_01213	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCDAONAO_01214	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HCDAONAO_01215	9.43e-90	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCDAONAO_01216	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCDAONAO_01217	2.81e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCDAONAO_01218	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCDAONAO_01219	7.16e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HCDAONAO_01220	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HCDAONAO_01221	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HCDAONAO_01222	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HCDAONAO_01223	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_01224	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCDAONAO_01225	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCDAONAO_01226	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCDAONAO_01227	8.28e-73	-	-	-	-	-	-	-	-
HCDAONAO_01228	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HCDAONAO_01229	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCDAONAO_01230	2.05e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCDAONAO_01231	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCDAONAO_01232	1.01e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCDAONAO_01233	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCDAONAO_01234	9.35e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HCDAONAO_01235	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HCDAONAO_01236	3.45e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCDAONAO_01237	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HCDAONAO_01238	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HCDAONAO_01239	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HCDAONAO_01240	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HCDAONAO_01241	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HCDAONAO_01242	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCDAONAO_01243	3.6e-243	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCDAONAO_01244	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCDAONAO_01245	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCDAONAO_01246	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HCDAONAO_01247	7.71e-298	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCDAONAO_01248	1.41e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HCDAONAO_01249	9.38e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCDAONAO_01250	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HCDAONAO_01251	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HCDAONAO_01252	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCDAONAO_01253	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HCDAONAO_01254	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCDAONAO_01255	8.49e-66	-	-	-	-	-	-	-	-
HCDAONAO_01256	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HCDAONAO_01257	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HCDAONAO_01258	9.06e-112	-	-	-	-	-	-	-	-
HCDAONAO_01259	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HCDAONAO_01260	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HCDAONAO_01262	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HCDAONAO_01263	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HCDAONAO_01264	6.03e-226	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HCDAONAO_01265	5.93e-166	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HCDAONAO_01266	1.57e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HCDAONAO_01267	1.54e-206	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HCDAONAO_01268	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HCDAONAO_01269	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
HCDAONAO_01270	2.04e-226	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HCDAONAO_01271	7.94e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HCDAONAO_01272	1.01e-155	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HCDAONAO_01273	1.51e-106	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HCDAONAO_01274	3.38e-274	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HCDAONAO_01275	1.89e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HCDAONAO_01276	5.19e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HCDAONAO_01278	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HCDAONAO_01279	1.62e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_01280	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCDAONAO_01281	4.64e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCDAONAO_01282	1.06e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCDAONAO_01283	5.75e-214	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HCDAONAO_01284	5.14e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HCDAONAO_01285	5.38e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCDAONAO_01286	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCDAONAO_01287	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HCDAONAO_01288	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HCDAONAO_01289	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCDAONAO_01290	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HCDAONAO_01291	2.29e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HCDAONAO_01292	8.32e-128	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HCDAONAO_01293	1.22e-160	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HCDAONAO_01294	3.06e-206	-	-	-	K	-	-	-	LysR substrate binding domain
HCDAONAO_01295	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HCDAONAO_01296	3.61e-245	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCDAONAO_01297	1.22e-120	-	-	-	K	-	-	-	transcriptional regulator
HCDAONAO_01298	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HCDAONAO_01299	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
HCDAONAO_01300	8.58e-71	-	-	-	-	-	-	-	-
HCDAONAO_01301	4.04e-33	-	-	-	-	-	-	-	-
HCDAONAO_01302	9.75e-276	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HCDAONAO_01303	5.76e-146	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HCDAONAO_01304	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HCDAONAO_01305	2.05e-55	-	-	-	-	-	-	-	-
HCDAONAO_01306	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HCDAONAO_01307	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HCDAONAO_01308	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HCDAONAO_01309	2.96e-210	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HCDAONAO_01310	7.21e-47	-	-	-	-	-	-	-	-
HCDAONAO_01311	5.79e-21	-	-	-	-	-	-	-	-
HCDAONAO_01312	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HCDAONAO_01313	4e-40	-	-	-	S	-	-	-	CsbD-like
HCDAONAO_01314	1.06e-53	-	-	-	-	-	-	-	-
HCDAONAO_01315	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCDAONAO_01316	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HCDAONAO_01317	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCDAONAO_01318	1.04e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HCDAONAO_01319	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HCDAONAO_01320	1.52e-67	-	-	-	-	-	-	-	-
HCDAONAO_01321	3.23e-58	-	-	-	-	-	-	-	-
HCDAONAO_01322	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCDAONAO_01323	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HCDAONAO_01324	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HCDAONAO_01325	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HCDAONAO_01326	6.56e-148	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HCDAONAO_01327	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HCDAONAO_01328	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HCDAONAO_01329	5.76e-148	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HCDAONAO_01330	2.09e-66	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HCDAONAO_01331	3.51e-250	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HCDAONAO_01332	1.77e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HCDAONAO_01333	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HCDAONAO_01334	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HCDAONAO_01335	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HCDAONAO_01336	4.2e-106	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HCDAONAO_01337	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HCDAONAO_01338	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HCDAONAO_01339	1.13e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HCDAONAO_01341	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCDAONAO_01342	1.41e-141	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCDAONAO_01343	3.19e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HCDAONAO_01344	1.31e-109	-	-	-	T	-	-	-	Universal stress protein family
HCDAONAO_01345	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCDAONAO_01346	1.98e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HCDAONAO_01347	2.21e-226	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HCDAONAO_01348	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HCDAONAO_01349	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCDAONAO_01350	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HCDAONAO_01351	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HCDAONAO_01353	4.11e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HCDAONAO_01354	1.7e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HCDAONAO_01355	7.86e-96	-	-	-	S	-	-	-	SnoaL-like domain
HCDAONAO_01356	1.67e-307	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HCDAONAO_01357	4.92e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HCDAONAO_01358	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCDAONAO_01359	1.23e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HCDAONAO_01360	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
HCDAONAO_01361	4.35e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HCDAONAO_01362	2.69e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCDAONAO_01363	6.5e-247	-	-	-	-	-	-	-	-
HCDAONAO_01364	7.14e-185	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HCDAONAO_01365	2.44e-267	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HCDAONAO_01366	4.66e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HCDAONAO_01367	5.89e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HCDAONAO_01368	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HCDAONAO_01369	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCDAONAO_01370	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HCDAONAO_01371	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCDAONAO_01372	1.71e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HCDAONAO_01373	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HCDAONAO_01374	9.58e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HCDAONAO_01375	8.72e-90	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HCDAONAO_01377	2.24e-167	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HCDAONAO_01378	4.92e-91	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HCDAONAO_01379	5.68e-175	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HCDAONAO_01381	4.59e-118	-	-	-	F	-	-	-	NUDIX domain
HCDAONAO_01382	1.77e-207	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_01383	1.6e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HCDAONAO_01384	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HCDAONAO_01385	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_01386	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HCDAONAO_01387	3.65e-103	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HCDAONAO_01388	2.9e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HCDAONAO_01389	2.15e-33	-	-	-	-	-	-	-	-
HCDAONAO_01390	2.37e-65	-	-	-	-	-	-	-	-
HCDAONAO_01391	4.17e-192	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HCDAONAO_01392	2.44e-267	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCDAONAO_01394	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HCDAONAO_01395	9.3e-167	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HCDAONAO_01396	1.05e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HCDAONAO_01397	7.45e-313	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HCDAONAO_01398	1.09e-178	-	-	-	-	-	-	-	-
HCDAONAO_01399	1.84e-76	-	-	-	-	-	-	-	-
HCDAONAO_01400	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HCDAONAO_01401	3.71e-286	-	-	-	-	-	-	-	-
HCDAONAO_01402	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HCDAONAO_01403	6.51e-247	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HCDAONAO_01404	4.99e-274	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCDAONAO_01405	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCDAONAO_01406	1.4e-122	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HCDAONAO_01407	1.48e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HCDAONAO_01408	5.7e-220	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HCDAONAO_01409	2.39e-226	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HCDAONAO_01410	4.49e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HCDAONAO_01411	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCDAONAO_01412	2.37e-250	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HCDAONAO_01413	4.19e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HCDAONAO_01414	8.64e-97	-	-	-	L	-	-	-	Transposase DDE domain
HCDAONAO_01415	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HCDAONAO_01416	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HCDAONAO_01417	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCDAONAO_01418	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HCDAONAO_01419	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HCDAONAO_01420	2.21e-227	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_01421	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCDAONAO_01422	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCDAONAO_01423	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCDAONAO_01424	1.04e-216	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HCDAONAO_01425	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HCDAONAO_01426	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HCDAONAO_01427	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HCDAONAO_01428	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HCDAONAO_01429	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCDAONAO_01430	1.1e-200	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HCDAONAO_01431	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCDAONAO_01432	1.85e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HCDAONAO_01433	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
HCDAONAO_01434	3.49e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HCDAONAO_01435	6.08e-91	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HCDAONAO_01436	2.38e-158	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HCDAONAO_01437	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HCDAONAO_01438	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HCDAONAO_01439	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HCDAONAO_01440	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HCDAONAO_01441	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HCDAONAO_01442	1.14e-206	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HCDAONAO_01443	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HCDAONAO_01444	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCDAONAO_01445	6.7e-241	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCDAONAO_01446	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_01447	6.46e-109	-	-	-	-	-	-	-	-
HCDAONAO_01448	5.18e-291	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCDAONAO_01449	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCDAONAO_01450	9.1e-193	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HCDAONAO_01451	2.08e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HCDAONAO_01452	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCDAONAO_01453	1.69e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HCDAONAO_01454	3.28e-280	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HCDAONAO_01455	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HCDAONAO_01456	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HCDAONAO_01457	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HCDAONAO_01458	5.61e-251	-	-	-	S	-	-	-	Helix-turn-helix domain
HCDAONAO_01459	1.51e-78	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCDAONAO_01460	7.01e-30	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCDAONAO_01461	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HCDAONAO_01462	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCDAONAO_01463	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCDAONAO_01464	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCDAONAO_01465	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HCDAONAO_01466	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HCDAONAO_01467	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HCDAONAO_01468	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HCDAONAO_01469	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HCDAONAO_01470	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HCDAONAO_01471	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HCDAONAO_01473	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCDAONAO_01474	2.6e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HCDAONAO_01475	6.55e-251	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCDAONAO_01476	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HCDAONAO_01477	5.84e-294	-	-	-	M	-	-	-	O-Antigen ligase
HCDAONAO_01478	8.81e-166	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HCDAONAO_01479	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HCDAONAO_01480	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HCDAONAO_01481	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HCDAONAO_01482	2.48e-51	-	-	-	P	-	-	-	Rhodanese Homology Domain
HCDAONAO_01483	4.3e-118	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HCDAONAO_01484	2.02e-268	-	-	-	-	-	-	-	-
HCDAONAO_01485	1.49e-281	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HCDAONAO_01486	3.55e-231	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HCDAONAO_01487	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HCDAONAO_01488	7.36e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCDAONAO_01489	6.53e-307	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HCDAONAO_01490	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_01491	6.03e-270	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HCDAONAO_01492	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCDAONAO_01493	4.83e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HCDAONAO_01494	1.4e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HCDAONAO_01495	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HCDAONAO_01496	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HCDAONAO_01497	4.88e-147	-	-	-	GM	-	-	-	epimerase
HCDAONAO_01498	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HCDAONAO_01499	3.54e-104	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCDAONAO_01500	1.12e-273	-	-	-	S	-	-	-	membrane
HCDAONAO_01501	1.55e-07	-	-	-	K	-	-	-	transcriptional regulator
HCDAONAO_01503	1.93e-35	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCDAONAO_01504	3.42e-12	-	-	-	S	-	-	-	protein with an alpha beta hydrolase fold
HCDAONAO_01505	6.03e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCDAONAO_01506	3.72e-147	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HCDAONAO_01507	4.67e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HCDAONAO_01508	2.13e-168	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HCDAONAO_01509	2.63e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
HCDAONAO_01510	4.15e-145	-	-	-	GM	-	-	-	NmrA-like family
HCDAONAO_01511	8.62e-102	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HCDAONAO_01512	2.33e-206	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_01513	4.61e-222	cryZ	-	-	C	-	-	-	nadph quinone reductase
HCDAONAO_01515	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCDAONAO_01516	1.11e-134	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HCDAONAO_01517	3.86e-261	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCDAONAO_01518	7.05e-172	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HCDAONAO_01519	1.63e-201	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HCDAONAO_01521	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HCDAONAO_01522	5.9e-103	-	-	-	K	-	-	-	MarR family
HCDAONAO_01523	1.28e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HCDAONAO_01524	0.000238	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HCDAONAO_01525	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_01526	4.08e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HCDAONAO_01527	6.08e-253	-	-	-	-	-	-	-	-
HCDAONAO_01528	1.44e-253	-	-	-	-	-	-	-	-
HCDAONAO_01529	2.45e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_01530	6.86e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HCDAONAO_01531	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCDAONAO_01532	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCDAONAO_01533	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HCDAONAO_01534	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HCDAONAO_01535	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HCDAONAO_01536	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCDAONAO_01537	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HCDAONAO_01538	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCDAONAO_01539	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HCDAONAO_01540	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HCDAONAO_01541	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HCDAONAO_01542	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCDAONAO_01543	3.65e-166	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HCDAONAO_01544	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HCDAONAO_01545	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCDAONAO_01546	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCDAONAO_01547	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCDAONAO_01548	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HCDAONAO_01549	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HCDAONAO_01550	2.83e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HCDAONAO_01551	4.4e-212	-	-	-	G	-	-	-	Fructosamine kinase
HCDAONAO_01552	6.97e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HCDAONAO_01553	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCDAONAO_01554	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCDAONAO_01555	1.49e-75	-	-	-	-	-	-	-	-
HCDAONAO_01556	7.36e-171	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HCDAONAO_01557	1.38e-224	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HCDAONAO_01558	1.35e-148	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HCDAONAO_01559	4.78e-65	-	-	-	-	-	-	-	-
HCDAONAO_01560	2.02e-66	-	-	-	-	-	-	-	-
HCDAONAO_01561	3.51e-19	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
HCDAONAO_01562	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCDAONAO_01563	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HCDAONAO_01564	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCDAONAO_01565	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HCDAONAO_01566	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCDAONAO_01567	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HCDAONAO_01568	1.26e-267	pbpX2	-	-	V	-	-	-	Beta-lactamase
HCDAONAO_01569	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCDAONAO_01570	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HCDAONAO_01571	4.72e-113	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCDAONAO_01572	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCDAONAO_01573	2.06e-170	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HCDAONAO_01574	9.2e-243	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HCDAONAO_01575	6.29e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCDAONAO_01576	2.31e-111	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HCDAONAO_01577	2.84e-244	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HCDAONAO_01578	8.18e-303	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HCDAONAO_01579	1.63e-121	-	-	-	-	-	-	-	-
HCDAONAO_01580	3.52e-273	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HCDAONAO_01581	0.0	-	-	-	G	-	-	-	Major Facilitator
HCDAONAO_01582	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCDAONAO_01583	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCDAONAO_01584	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HCDAONAO_01585	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HCDAONAO_01586	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HCDAONAO_01587	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HCDAONAO_01588	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCDAONAO_01589	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCDAONAO_01590	1.89e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HCDAONAO_01591	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HCDAONAO_01592	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCDAONAO_01593	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCDAONAO_01594	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HCDAONAO_01595	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCDAONAO_01596	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HCDAONAO_01597	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HCDAONAO_01598	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCDAONAO_01599	5.67e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HCDAONAO_01600	2.11e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HCDAONAO_01601	1.71e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HCDAONAO_01602	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HCDAONAO_01603	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HCDAONAO_01604	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCDAONAO_01605	3.7e-121	-	-	-	-	-	-	-	-
HCDAONAO_01606	5.44e-277	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HCDAONAO_01607	1.01e-100	-	-	-	-	-	-	-	-
HCDAONAO_01608	3.81e-87	-	-	-	-	-	-	-	-
HCDAONAO_01609	1.14e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HCDAONAO_01610	6.27e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HCDAONAO_01611	4.46e-281	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HCDAONAO_01612	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCDAONAO_01613	1.19e-270	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCDAONAO_01614	1.46e-135	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HCDAONAO_01615	2.78e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HCDAONAO_01617	1.75e-43	-	-	-	-	-	-	-	-
HCDAONAO_01618	1.02e-183	-	-	-	Q	-	-	-	Methyltransferase
HCDAONAO_01619	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HCDAONAO_01620	1.3e-266	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HCDAONAO_01621	1.25e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
HCDAONAO_01622	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCDAONAO_01623	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HCDAONAO_01624	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HCDAONAO_01625	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HCDAONAO_01626	8.34e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HCDAONAO_01627	6.62e-62	-	-	-	-	-	-	-	-
HCDAONAO_01628	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCDAONAO_01629	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HCDAONAO_01630	8.57e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HCDAONAO_01631	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HCDAONAO_01632	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HCDAONAO_01633	0.0	cps4J	-	-	S	-	-	-	MatE
HCDAONAO_01634	3.4e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HCDAONAO_01635	1.91e-297	-	-	-	-	-	-	-	-
HCDAONAO_01636	1.94e-244	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HCDAONAO_01637	1.15e-258	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HCDAONAO_01638	3.31e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HCDAONAO_01639	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HCDAONAO_01640	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HCDAONAO_01641	2.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HCDAONAO_01642	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
HCDAONAO_01643	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCDAONAO_01644	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_01645	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HCDAONAO_01646	5.12e-31	-	-	-	-	-	-	-	-
HCDAONAO_01647	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HCDAONAO_01648	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HCDAONAO_01649	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HCDAONAO_01650	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCDAONAO_01651	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCDAONAO_01652	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCDAONAO_01653	2.2e-199	-	-	-	S	-	-	-	Tetratricopeptide repeat
HCDAONAO_01654	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCDAONAO_01655	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCDAONAO_01656	3.12e-131	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCDAONAO_01657	8.25e-113	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCDAONAO_01658	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCDAONAO_01659	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HCDAONAO_01660	2.07e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HCDAONAO_01661	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HCDAONAO_01662	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HCDAONAO_01663	5.47e-157	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HCDAONAO_01664	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HCDAONAO_01665	2.99e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCDAONAO_01666	9.66e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HCDAONAO_01667	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HCDAONAO_01668	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HCDAONAO_01669	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HCDAONAO_01670	0.0	-	-	-	-	-	-	-	-
HCDAONAO_01671	4.61e-87	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HCDAONAO_01672	3.1e-214	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HCDAONAO_01673	9.51e-135	-	-	-	-	-	-	-	-
HCDAONAO_01674	1.1e-257	-	-	-	-	-	-	-	-
HCDAONAO_01675	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HCDAONAO_01676	1.23e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HCDAONAO_01677	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HCDAONAO_01678	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HCDAONAO_01679	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HCDAONAO_01680	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCDAONAO_01681	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HCDAONAO_01682	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HCDAONAO_01683	3.25e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCDAONAO_01684	6.45e-111	-	-	-	-	-	-	-	-
HCDAONAO_01685	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HCDAONAO_01686	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCDAONAO_01687	5.96e-241	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HCDAONAO_01688	2.16e-39	-	-	-	-	-	-	-	-
HCDAONAO_01689	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HCDAONAO_01690	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCDAONAO_01691	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HCDAONAO_01692	1.02e-155	-	-	-	S	-	-	-	repeat protein
HCDAONAO_01693	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HCDAONAO_01694	0.0	-	-	-	N	-	-	-	domain, Protein
HCDAONAO_01695	7.05e-248	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HCDAONAO_01696	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HCDAONAO_01697	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HCDAONAO_01698	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HCDAONAO_01699	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCDAONAO_01700	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HCDAONAO_01701	1.5e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HCDAONAO_01702	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCDAONAO_01703	7.74e-47	-	-	-	-	-	-	-	-
HCDAONAO_01704	1.18e-123	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HCDAONAO_01705	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCDAONAO_01706	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCDAONAO_01707	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HCDAONAO_01708	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HCDAONAO_01709	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HCDAONAO_01710	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCDAONAO_01711	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCDAONAO_01712	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCDAONAO_01713	4.73e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HCDAONAO_01714	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCDAONAO_01715	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCDAONAO_01716	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCDAONAO_01717	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HCDAONAO_01718	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HCDAONAO_01719	2.12e-225	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCDAONAO_01720	7.24e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HCDAONAO_01721	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HCDAONAO_01722	1.43e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HCDAONAO_01723	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HCDAONAO_01724	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCDAONAO_01725	7.16e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HCDAONAO_01726	1.25e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HCDAONAO_01728	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HCDAONAO_01729	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCDAONAO_01730	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HCDAONAO_01731	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HCDAONAO_01732	5.57e-247	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HCDAONAO_01733	2.51e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HCDAONAO_01734	2.57e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HCDAONAO_01735	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCDAONAO_01736	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HCDAONAO_01737	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HCDAONAO_01738	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HCDAONAO_01739	7.84e-265	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HCDAONAO_01740	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HCDAONAO_01741	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCDAONAO_01742	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HCDAONAO_01743	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HCDAONAO_01765	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HCDAONAO_01766	1.24e-76	-	-	-	-	-	-	-	-
HCDAONAO_01767	1.95e-114	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HCDAONAO_01768	4.05e-211	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCDAONAO_01769	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HCDAONAO_01770	1.22e-139	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCDAONAO_01771	7.18e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HCDAONAO_01772	3.3e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HCDAONAO_01773	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCDAONAO_01774	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HCDAONAO_01775	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HCDAONAO_01776	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HCDAONAO_01777	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HCDAONAO_01778	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCDAONAO_01779	2.22e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HCDAONAO_01781	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HCDAONAO_01782	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HCDAONAO_01783	4.29e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HCDAONAO_01784	5.66e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HCDAONAO_01785	5.09e-241	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HCDAONAO_01786	1.55e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HCDAONAO_01787	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCDAONAO_01788	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HCDAONAO_01789	6.99e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HCDAONAO_01790	6.48e-210	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HCDAONAO_01791	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HCDAONAO_01792	1.55e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HCDAONAO_01793	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HCDAONAO_01794	1.47e-92	-	-	-	-	-	-	-	-
HCDAONAO_01795	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HCDAONAO_01796	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HCDAONAO_01797	6.72e-289	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HCDAONAO_01798	1.61e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HCDAONAO_01799	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HCDAONAO_01800	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HCDAONAO_01801	8.15e-142	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCDAONAO_01802	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HCDAONAO_01803	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HCDAONAO_01804	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HCDAONAO_01805	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCDAONAO_01806	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HCDAONAO_01807	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HCDAONAO_01808	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCDAONAO_01809	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HCDAONAO_01810	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCDAONAO_01811	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HCDAONAO_01812	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HCDAONAO_01813	5.01e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCDAONAO_01814	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HCDAONAO_01815	2.84e-288	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCDAONAO_01816	4.82e-255	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HCDAONAO_01817	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCDAONAO_01818	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCDAONAO_01819	9.86e-117	-	-	-	-	-	-	-	-
HCDAONAO_01820	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HCDAONAO_01821	1.35e-93	-	-	-	-	-	-	-	-
HCDAONAO_01822	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCDAONAO_01823	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCDAONAO_01824	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HCDAONAO_01825	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HCDAONAO_01826	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCDAONAO_01827	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HCDAONAO_01828	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCDAONAO_01829	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HCDAONAO_01830	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HCDAONAO_01831	8.72e-297	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HCDAONAO_01832	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HCDAONAO_01833	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HCDAONAO_01834	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_01835	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HCDAONAO_01836	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HCDAONAO_01837	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HCDAONAO_01838	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HCDAONAO_01839	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HCDAONAO_01840	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HCDAONAO_01841	3.18e-148	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HCDAONAO_01842	3.28e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HCDAONAO_01843	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCDAONAO_01844	5.06e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCDAONAO_01845	2.6e-298	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HCDAONAO_01846	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HCDAONAO_01847	8.66e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HCDAONAO_01848	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HCDAONAO_01849	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HCDAONAO_01850	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCDAONAO_01851	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HCDAONAO_01852	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HCDAONAO_01853	1.83e-141	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HCDAONAO_01854	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HCDAONAO_01855	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HCDAONAO_01856	2.08e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HCDAONAO_01857	1.34e-52	-	-	-	-	-	-	-	-
HCDAONAO_01858	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HCDAONAO_01859	3.3e-260	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HCDAONAO_01860	1.57e-205	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCDAONAO_01861	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HCDAONAO_01862	3.78e-272	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HCDAONAO_01863	3.59e-240	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HCDAONAO_01864	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HCDAONAO_01865	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HCDAONAO_01866	3.03e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HCDAONAO_01867	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCDAONAO_01868	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCDAONAO_01869	7.22e-60	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HCDAONAO_01870	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HCDAONAO_01871	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HCDAONAO_01872	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HCDAONAO_01873	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HCDAONAO_01874	5.63e-131	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HCDAONAO_01875	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCDAONAO_01876	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HCDAONAO_01877	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCDAONAO_01878	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCDAONAO_01879	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCDAONAO_01880	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCDAONAO_01881	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCDAONAO_01882	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCDAONAO_01883	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HCDAONAO_01884	2.49e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HCDAONAO_01885	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCDAONAO_01886	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCDAONAO_01887	1.03e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCDAONAO_01888	3.44e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCDAONAO_01889	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCDAONAO_01890	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HCDAONAO_01891	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HCDAONAO_01892	2.5e-173	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HCDAONAO_01893	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HCDAONAO_01894	7.59e-245	ampC	-	-	V	-	-	-	Beta-lactamase
HCDAONAO_01895	2.1e-41	-	-	-	-	-	-	-	-
HCDAONAO_01896	7.74e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HCDAONAO_01897	1.33e-77	-	-	-	-	-	-	-	-
HCDAONAO_01898	5.37e-182	-	-	-	-	-	-	-	-
HCDAONAO_01899	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HCDAONAO_01900	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_01901	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HCDAONAO_01902	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HCDAONAO_01904	2.93e-73	-	-	-	V	-	-	-	Abortive infection bacteriophage resistance protein
HCDAONAO_01905	1.18e-66	-	-	-	S	-	-	-	Bacteriophage holin
HCDAONAO_01906	7.86e-65	-	-	-	-	-	-	-	-
HCDAONAO_01907	4.58e-254	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HCDAONAO_01908	2.66e-07	xhlB	-	-	S	-	-	-	SPP1 phage holin
HCDAONAO_01910	1.73e-47	-	-	-	-	-	-	-	-
HCDAONAO_01912	3.13e-42	-	-	-	E	ko:K20306	-	ko00000,ko04131	lipolytic protein G-D-S-L family
HCDAONAO_01914	2.86e-202	-	-	-	S	-	-	-	Prophage endopeptidase tail
HCDAONAO_01915	5.75e-155	-	-	-	S	-	-	-	Phage tail protein
HCDAONAO_01916	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HCDAONAO_01917	2.99e-133	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
HCDAONAO_01919	4.83e-100	-	-	-	-	-	-	-	-
HCDAONAO_01920	4.06e-84	-	-	-	S	-	-	-	Minor capsid protein from bacteriophage
HCDAONAO_01921	1.18e-60	-	-	-	S	-	-	-	Minor capsid protein
HCDAONAO_01922	7.17e-70	-	-	-	S	-	-	-	Minor capsid protein
HCDAONAO_01923	5.08e-09	-	-	-	-	-	-	-	-
HCDAONAO_01924	3.36e-237	-	-	-	S	-	-	-	viral capsid
HCDAONAO_01925	9.2e-108	-	-	-	S	-	-	-	Phage minor structural protein GP20
HCDAONAO_01927	9.01e-209	-	-	-	S	-	-	-	Phage minor capsid protein 2
HCDAONAO_01928	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HCDAONAO_01929	0.0	-	-	-	S	-	-	-	Phage terminase large subunit
HCDAONAO_01930	4.48e-85	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HCDAONAO_01932	9.25e-20	-	-	-	V	-	-	-	HNH nucleases
HCDAONAO_01937	2.15e-106	arpU	-	-	S	-	-	-	Transcriptional regulator, ArpU family
HCDAONAO_01938	6.5e-26	-	-	-	-	-	-	-	-
HCDAONAO_01939	9.86e-39	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HCDAONAO_01940	1.26e-19	-	-	-	S	-	-	-	YjzC-like protein
HCDAONAO_01942	7.47e-88	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HCDAONAO_01943	8.72e-111	-	-	-	-	-	-	-	-
HCDAONAO_01944	2.2e-65	-	-	-	-	-	-	-	-
HCDAONAO_01945	4.41e-218	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
HCDAONAO_01946	1.57e-80	-	-	-	-	-	-	-	-
HCDAONAO_01947	2.8e-70	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HCDAONAO_01950	1.56e-103	-	-	-	-	-	-	-	-
HCDAONAO_01951	1.82e-69	-	-	-	-	-	-	-	-
HCDAONAO_01955	3.41e-41	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HCDAONAO_01957	2.57e-07	-	-	-	K	-	-	-	Transcriptional
HCDAONAO_01958	1.38e-82	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCDAONAO_01959	2.73e-97	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HCDAONAO_01960	2.64e-202	-	-	-	J	-	-	-	Domain of unknown function (DUF4041)
HCDAONAO_01965	1.09e-57	-	-	-	S	-	-	-	AAA ATPase domain
HCDAONAO_01966	8.64e-97	-	-	-	L	-	-	-	Transposase DDE domain
HCDAONAO_01967	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HCDAONAO_01968	1.51e-24	-	-	-	S	-	-	-	AAA ATPase domain
HCDAONAO_01969	1.58e-98	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	DNA mismatch endonuclease Vsr
HCDAONAO_01970	2.12e-275	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCDAONAO_01972	1.98e-40	-	-	-	-	-	-	-	-
HCDAONAO_01975	4.88e-79	-	-	-	-	-	-	-	-
HCDAONAO_01976	8.32e-56	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HCDAONAO_01977	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HCDAONAO_01978	3.18e-262	-	-	-	S	-	-	-	Phage portal protein
HCDAONAO_01979	0.000495	-	-	-	-	-	-	-	-
HCDAONAO_01980	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HCDAONAO_01981	4.3e-106	-	-	-	L	-	-	-	overlaps another CDS with the same product name
HCDAONAO_01982	2.59e-89	-	-	-	L	-	-	-	HNH endonuclease
HCDAONAO_01983	7.63e-65	-	-	-	S	-	-	-	Head-tail joining protein
HCDAONAO_01985	3.36e-96	-	-	-	-	-	-	-	-
HCDAONAO_01986	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
HCDAONAO_01987	9.72e-184	-	-	-	L	-	-	-	DNA replication protein
HCDAONAO_01988	3.18e-41	-	-	-	-	-	-	-	-
HCDAONAO_01990	3.96e-13	-	-	-	-	-	-	-	-
HCDAONAO_01992	1.1e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	transcriptional regulator
HCDAONAO_01993	2.54e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCDAONAO_01994	1.28e-51	-	-	-	-	-	-	-	-
HCDAONAO_01995	9.28e-58	-	-	-	-	-	-	-	-
HCDAONAO_01996	1.27e-109	-	-	-	K	-	-	-	MarR family
HCDAONAO_01997	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HCDAONAO_01998	0.0	inlJ	-	-	M	-	-	-	MucBP domain
HCDAONAO_01999	6.58e-24	-	-	-	-	-	-	-	-
HCDAONAO_02000	3.26e-24	-	-	-	-	-	-	-	-
HCDAONAO_02001	1.56e-22	-	-	-	-	-	-	-	-
HCDAONAO_02002	1.07e-26	-	-	-	-	-	-	-	-
HCDAONAO_02003	9.35e-24	-	-	-	-	-	-	-	-
HCDAONAO_02004	4.48e-22	-	-	-	-	-	-	-	-
HCDAONAO_02005	9.35e-24	-	-	-	-	-	-	-	-
HCDAONAO_02006	2.16e-26	-	-	-	-	-	-	-	-
HCDAONAO_02007	4.63e-24	-	-	-	-	-	-	-	-
HCDAONAO_02008	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HCDAONAO_02009	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HCDAONAO_02010	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_02011	2.1e-33	-	-	-	-	-	-	-	-
HCDAONAO_02012	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HCDAONAO_02013	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HCDAONAO_02014	1.75e-275	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HCDAONAO_02015	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HCDAONAO_02016	5.89e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HCDAONAO_02017	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HCDAONAO_02018	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HCDAONAO_02019	5.15e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HCDAONAO_02025	1.03e-156	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
HCDAONAO_02028	6.19e-284	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HCDAONAO_02030	7.38e-78	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
HCDAONAO_02032	6.73e-133	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HCDAONAO_02033	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HCDAONAO_02034	1.31e-64	-	-	-	-	-	-	-	-
HCDAONAO_02035	9.26e-226	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HCDAONAO_02036	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
HCDAONAO_02037	2.68e-32	-	-	-	-	-	-	-	-
HCDAONAO_02039	2e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCDAONAO_02040	4.27e-223	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HCDAONAO_02041	5.92e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HCDAONAO_02042	2.29e-48	-	-	-	-	-	-	-	-
HCDAONAO_02043	1.11e-45	-	-	-	-	-	-	-	-
HCDAONAO_02044	2.81e-278	-	-	-	T	-	-	-	diguanylate cyclase
HCDAONAO_02045	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HCDAONAO_02046	8.64e-97	-	-	-	L	-	-	-	Transposase DDE domain
HCDAONAO_02047	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HCDAONAO_02048	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HCDAONAO_02049	2.35e-106	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCDAONAO_02050	2.64e-61	-	-	-	-	-	-	-	-
HCDAONAO_02051	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HCDAONAO_02052	2.53e-240	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCDAONAO_02053	5.97e-210	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HCDAONAO_02054	4.97e-213	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HCDAONAO_02055	1.66e-61	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HCDAONAO_02056	2.48e-311	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HCDAONAO_02057	4.4e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HCDAONAO_02058	1.13e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HCDAONAO_02059	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HCDAONAO_02060	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_02061	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HCDAONAO_02062	2.34e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HCDAONAO_02063	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HCDAONAO_02064	7.09e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HCDAONAO_02065	4.3e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HCDAONAO_02066	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HCDAONAO_02067	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HCDAONAO_02068	5.18e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HCDAONAO_02069	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HCDAONAO_02070	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HCDAONAO_02071	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HCDAONAO_02072	1.92e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HCDAONAO_02073	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HCDAONAO_02074	1.39e-276	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HCDAONAO_02075	1.12e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HCDAONAO_02076	3.05e-282	ysaA	-	-	V	-	-	-	RDD family
HCDAONAO_02077	1.47e-212	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HCDAONAO_02078	2.83e-66	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HCDAONAO_02079	2.54e-17	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HCDAONAO_02080	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCDAONAO_02081	9.88e-239	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCDAONAO_02082	4.15e-46	-	-	-	-	-	-	-	-
HCDAONAO_02083	5.14e-143	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HCDAONAO_02084	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HCDAONAO_02085	0.0	-	-	-	M	-	-	-	domain protein
HCDAONAO_02086	3e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HCDAONAO_02087	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCDAONAO_02088	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HCDAONAO_02089	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HCDAONAO_02090	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCDAONAO_02091	7.24e-250	-	-	-	S	-	-	-	domain, Protein
HCDAONAO_02092	4.08e-215	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HCDAONAO_02093	4.26e-127	-	-	-	C	-	-	-	Nitroreductase family
HCDAONAO_02094	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HCDAONAO_02095	3.45e-209	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCDAONAO_02096	1.27e-156	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HCDAONAO_02097	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
HCDAONAO_02098	4.16e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HCDAONAO_02099	2.48e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HCDAONAO_02100	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HCDAONAO_02101	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HCDAONAO_02102	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCDAONAO_02103	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HCDAONAO_02104	2.66e-172	-	-	-	-	-	-	-	-
HCDAONAO_02105	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HCDAONAO_02106	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HCDAONAO_02107	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HCDAONAO_02108	6.56e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HCDAONAO_02109	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HCDAONAO_02110	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_02111	1.86e-210	-	-	-	-	-	-	-	-
HCDAONAO_02112	1.28e-77	-	-	-	-	-	-	-	-
HCDAONAO_02113	4.83e-64	-	-	-	-	-	-	-	-
HCDAONAO_02114	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HCDAONAO_02115	4.09e-89	-	-	-	-	-	-	-	-
HCDAONAO_02116	2.4e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HCDAONAO_02117	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HCDAONAO_02118	6.69e-263	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HCDAONAO_02119	3.89e-62	-	-	-	-	-	-	-	-
HCDAONAO_02120	1.47e-69	-	-	-	-	-	-	-	-
HCDAONAO_02121	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HCDAONAO_02122	4.05e-98	-	-	-	-	-	-	-	-
HCDAONAO_02123	4.15e-78	-	-	-	-	-	-	-	-
HCDAONAO_02124	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HCDAONAO_02125	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HCDAONAO_02126	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HCDAONAO_02127	8.64e-97	-	-	-	L	-	-	-	Transposase DDE domain
HCDAONAO_02128	7.2e-103	uspA3	-	-	T	-	-	-	universal stress protein
HCDAONAO_02129	1.02e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HCDAONAO_02130	3.77e-24	-	-	-	-	-	-	-	-
HCDAONAO_02131	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
HCDAONAO_02132	8.5e-98	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HCDAONAO_02133	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HCDAONAO_02134	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HCDAONAO_02135	3.07e-284	-	-	-	M	-	-	-	Glycosyl transferases group 1
HCDAONAO_02136	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HCDAONAO_02137	3.45e-182	-	-	-	S	-	-	-	Putative esterase
HCDAONAO_02138	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_02139	6.74e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCDAONAO_02140	1.01e-177	-	-	-	-	-	-	-	-
HCDAONAO_02141	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HCDAONAO_02142	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HCDAONAO_02143	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HCDAONAO_02144	1.55e-79	-	-	-	-	-	-	-	-
HCDAONAO_02145	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HCDAONAO_02146	2.97e-76	-	-	-	-	-	-	-	-
HCDAONAO_02147	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HCDAONAO_02148	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HCDAONAO_02149	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HCDAONAO_02150	1.17e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
HCDAONAO_02151	4.71e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HCDAONAO_02152	2.19e-220	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HCDAONAO_02153	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HCDAONAO_02154	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCDAONAO_02155	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HCDAONAO_02156	2.91e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCDAONAO_02157	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCDAONAO_02158	3.59e-26	-	-	-	-	-	-	-	-
HCDAONAO_02159	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HCDAONAO_02160	6.68e-207	mleR	-	-	K	-	-	-	LysR family
HCDAONAO_02161	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HCDAONAO_02162	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HCDAONAO_02163	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HCDAONAO_02164	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HCDAONAO_02165	1.56e-217	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HCDAONAO_02166	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCDAONAO_02167	1.09e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HCDAONAO_02168	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCDAONAO_02169	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HCDAONAO_02170	3.36e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HCDAONAO_02171	2.38e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCDAONAO_02172	1.22e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HCDAONAO_02173	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCDAONAO_02174	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HCDAONAO_02175	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HCDAONAO_02176	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HCDAONAO_02177	3.87e-207	-	-	-	GM	-	-	-	NmrA-like family
HCDAONAO_02178	1.46e-198	-	-	-	T	-	-	-	EAL domain
HCDAONAO_02179	2.62e-121	-	-	-	-	-	-	-	-
HCDAONAO_02180	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HCDAONAO_02181	4.17e-163	-	-	-	E	-	-	-	Methionine synthase
HCDAONAO_02182	2.23e-279	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HCDAONAO_02183	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HCDAONAO_02184	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HCDAONAO_02185	2.97e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HCDAONAO_02186	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCDAONAO_02187	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCDAONAO_02188	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCDAONAO_02189	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCDAONAO_02190	9.7e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HCDAONAO_02191	1.17e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCDAONAO_02192	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCDAONAO_02193	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HCDAONAO_02194	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HCDAONAO_02195	2.01e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HCDAONAO_02196	1.18e-188	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HCDAONAO_02197	2.42e-152	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HCDAONAO_02198	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCDAONAO_02199	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HCDAONAO_02200	9.74e-177	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_02201	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HCDAONAO_02202	4.76e-56	-	-	-	-	-	-	-	-
HCDAONAO_02203	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HCDAONAO_02204	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_02205	3.41e-190	-	-	-	-	-	-	-	-
HCDAONAO_02206	1.1e-103	usp5	-	-	T	-	-	-	universal stress protein
HCDAONAO_02207	1.08e-47	-	-	-	-	-	-	-	-
HCDAONAO_02208	5.7e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HCDAONAO_02209	1.76e-114	-	-	-	-	-	-	-	-
HCDAONAO_02210	1.02e-67	-	-	-	-	-	-	-	-
HCDAONAO_02211	4.79e-13	-	-	-	-	-	-	-	-
HCDAONAO_02212	5.02e-298	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HCDAONAO_02213	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HCDAONAO_02214	1.52e-151	-	-	-	-	-	-	-	-
HCDAONAO_02215	1.21e-69	-	-	-	-	-	-	-	-
HCDAONAO_02217	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HCDAONAO_02218	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HCDAONAO_02219	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HCDAONAO_02220	4.72e-40	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HCDAONAO_02221	2.05e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HCDAONAO_02222	1.13e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HCDAONAO_02223	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HCDAONAO_02224	6.58e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HCDAONAO_02225	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HCDAONAO_02226	6.01e-270	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HCDAONAO_02227	2.56e-293	-	-	-	S	-	-	-	Sterol carrier protein domain
HCDAONAO_02228	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HCDAONAO_02229	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCDAONAO_02230	2.13e-152	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_02231	9.76e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HCDAONAO_02232	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HCDAONAO_02233	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HCDAONAO_02234	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HCDAONAO_02235	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HCDAONAO_02236	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HCDAONAO_02237	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HCDAONAO_02238	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HCDAONAO_02239	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HCDAONAO_02240	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HCDAONAO_02241	7.63e-107	-	-	-	-	-	-	-	-
HCDAONAO_02242	5.06e-196	-	-	-	S	-	-	-	hydrolase
HCDAONAO_02243	7.17e-234	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCDAONAO_02244	1.14e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HCDAONAO_02245	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HCDAONAO_02246	3.78e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HCDAONAO_02247	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HCDAONAO_02248	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HCDAONAO_02249	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HCDAONAO_02250	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HCDAONAO_02251	5.44e-198	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HCDAONAO_02252	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HCDAONAO_02253	4.3e-44	-	-	-	-	-	-	-	-
HCDAONAO_02254	6.01e-165	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HCDAONAO_02255	0.0	ycaM	-	-	E	-	-	-	amino acid
HCDAONAO_02256	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HCDAONAO_02257	2.35e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HCDAONAO_02258	1.2e-206	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HCDAONAO_02259	1.86e-214	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HCDAONAO_02260	1.3e-209	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_02262	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HCDAONAO_02263	5.04e-111	-	-	-	S	-	-	-	Pfam:DUF3816
HCDAONAO_02264	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCDAONAO_02265	1.27e-143	-	-	-	-	-	-	-	-
HCDAONAO_02266	5.37e-230	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HCDAONAO_02267	2.22e-184	-	-	-	S	-	-	-	Peptidase_C39 like family
HCDAONAO_02268	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HCDAONAO_02269	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HCDAONAO_02270	3.82e-188	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HCDAONAO_02271	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCDAONAO_02272	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HCDAONAO_02273	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HCDAONAO_02274	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_02275	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HCDAONAO_02276	4.9e-239	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HCDAONAO_02277	2.92e-126	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HCDAONAO_02278	1.97e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCDAONAO_02279	9.01e-155	-	-	-	S	-	-	-	Membrane
HCDAONAO_02280	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HCDAONAO_02281	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HCDAONAO_02282	1.41e-250	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCDAONAO_02283	5.94e-162	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HCDAONAO_02284	4.95e-271	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HCDAONAO_02285	3.65e-46	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HCDAONAO_02286	2.43e-105	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HCDAONAO_02287	6.08e-131	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HCDAONAO_02288	4.38e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HCDAONAO_02289	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HCDAONAO_02290	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HCDAONAO_02291	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HCDAONAO_02293	7.76e-77	-	-	-	M	-	-	-	LysM domain
HCDAONAO_02294	1.6e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HCDAONAO_02295	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_02296	5.31e-267	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HCDAONAO_02297	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HCDAONAO_02298	1.16e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HCDAONAO_02299	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HCDAONAO_02300	1.27e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HCDAONAO_02301	4.35e-301	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HCDAONAO_02302	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HCDAONAO_02303	1.17e-154	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_02305	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCDAONAO_02306	5.27e-140	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HCDAONAO_02307	2e-148	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HCDAONAO_02308	9.14e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HCDAONAO_02309	9.82e-111	-	-	-	-	-	-	-	-
HCDAONAO_02310	1.08e-112	yvbK	-	-	K	-	-	-	GNAT family
HCDAONAO_02311	9.76e-50	-	-	-	-	-	-	-	-
HCDAONAO_02312	2.81e-64	-	-	-	-	-	-	-	-
HCDAONAO_02313	1.56e-144	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HCDAONAO_02314	1.75e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HCDAONAO_02315	6.67e-204	-	-	-	K	-	-	-	LysR substrate binding domain
HCDAONAO_02316	1.07e-135	-	-	-	GM	-	-	-	NAD(P)H-binding
HCDAONAO_02317	5.8e-248	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HCDAONAO_02318	2.78e-192	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HCDAONAO_02319	1.28e-45	-	-	-	-	-	-	-	-
HCDAONAO_02320	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HCDAONAO_02321	7e-123	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HCDAONAO_02322	2.92e-161	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HCDAONAO_02323	6e-54	-	-	-	-	-	-	-	-
HCDAONAO_02324	5.09e-283	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HCDAONAO_02325	6.86e-42	-	-	-	-	-	-	-	-
HCDAONAO_02326	1.52e-130	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HCDAONAO_02327	9.9e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HCDAONAO_02328	1.31e-132	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HCDAONAO_02329	3.35e-245	-	-	-	C	-	-	-	Aldo/keto reductase family
HCDAONAO_02331	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCDAONAO_02332	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCDAONAO_02333	6.27e-316	-	-	-	EGP	-	-	-	Major Facilitator
HCDAONAO_02337	1.24e-229	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HCDAONAO_02338	1.79e-140	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HCDAONAO_02339	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HCDAONAO_02340	4.17e-195	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HCDAONAO_02341	2.31e-133	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HCDAONAO_02342	3.05e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HCDAONAO_02343	6.26e-289	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HCDAONAO_02344	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HCDAONAO_02345	5.69e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HCDAONAO_02346	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HCDAONAO_02347	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HCDAONAO_02348	1.27e-34	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
HCDAONAO_02349	2.84e-266	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HCDAONAO_02350	4.94e-78	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCDAONAO_02351	4.03e-124	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCDAONAO_02352	1.44e-226	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HCDAONAO_02353	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino acid permease
HCDAONAO_02354	2.83e-297	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HCDAONAO_02355	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HCDAONAO_02356	2.85e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCDAONAO_02357	6.11e-169	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HCDAONAO_02358	0.0	-	-	-	-	-	-	-	-
HCDAONAO_02359	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HCDAONAO_02360	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCDAONAO_02361	5.88e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HCDAONAO_02362	8.07e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HCDAONAO_02363	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCDAONAO_02364	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HCDAONAO_02365	6.36e-108	-	-	-	-	-	-	-	-
HCDAONAO_02366	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HCDAONAO_02367	6.48e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCDAONAO_02368	7.3e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCDAONAO_02369	3.7e-30	-	-	-	-	-	-	-	-
HCDAONAO_02370	9.73e-132	-	-	-	-	-	-	-	-
HCDAONAO_02371	3.46e-210	-	-	-	K	-	-	-	LysR substrate binding domain
HCDAONAO_02372	1.98e-109	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HCDAONAO_02373	1.77e-187	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HCDAONAO_02374	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HCDAONAO_02375	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HCDAONAO_02376	7.99e-184	-	-	-	S	-	-	-	zinc-ribbon domain
HCDAONAO_02378	4.29e-50	-	-	-	-	-	-	-	-
HCDAONAO_02379	5.17e-172	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HCDAONAO_02380	4.74e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HCDAONAO_02381	0.0	-	-	-	I	-	-	-	acetylesterase activity
HCDAONAO_02382	1.01e-297	-	-	-	M	-	-	-	Collagen binding domain
HCDAONAO_02383	3.43e-206	yicL	-	-	EG	-	-	-	EamA-like transporter family
HCDAONAO_02384	2.91e-164	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HCDAONAO_02385	3.53e-227	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HCDAONAO_02386	6.64e-141	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HCDAONAO_02387	2.23e-60	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HCDAONAO_02388	1.7e-203	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HCDAONAO_02389	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HCDAONAO_02390	1.56e-125	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HCDAONAO_02391	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
HCDAONAO_02392	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HCDAONAO_02393	4.21e-150	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCDAONAO_02394	2.48e-199	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HCDAONAO_02395	7.28e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HCDAONAO_02396	0.0	-	-	-	-	-	-	-	-
HCDAONAO_02397	6.69e-81	-	-	-	-	-	-	-	-
HCDAONAO_02398	3.73e-240	-	-	-	S	-	-	-	Cell surface protein
HCDAONAO_02399	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HCDAONAO_02400	6.39e-123	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HCDAONAO_02401	7.96e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCDAONAO_02402	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HCDAONAO_02403	1.88e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HCDAONAO_02404	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HCDAONAO_02405	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HCDAONAO_02407	1.15e-43	-	-	-	-	-	-	-	-
HCDAONAO_02408	2.93e-169	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HCDAONAO_02409	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HCDAONAO_02410	5.67e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCDAONAO_02411	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HCDAONAO_02412	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HCDAONAO_02413	7.03e-62	-	-	-	-	-	-	-	-
HCDAONAO_02414	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HCDAONAO_02415	1e-63	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HCDAONAO_02416	2.26e-123	-	-	-	P	-	-	-	Cadmium resistance transporter
HCDAONAO_02417	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_02418	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HCDAONAO_02419	2.03e-84	-	-	-	-	-	-	-	-
HCDAONAO_02420	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HCDAONAO_02421	1.21e-73	-	-	-	-	-	-	-	-
HCDAONAO_02422	7.18e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
HCDAONAO_02423	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCDAONAO_02424	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HCDAONAO_02425	1.5e-303	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCDAONAO_02426	1.33e-18	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCDAONAO_02427	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HCDAONAO_02428	1.76e-234	-	-	-	GM	-	-	-	Male sterility protein
HCDAONAO_02429	1.21e-98	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HCDAONAO_02430	2.18e-99	-	-	-	M	-	-	-	LysM domain
HCDAONAO_02431	3.03e-130	-	-	-	M	-	-	-	Lysin motif
HCDAONAO_02432	1.99e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
HCDAONAO_02433	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HCDAONAO_02434	6.73e-211	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HCDAONAO_02435	3.57e-120	-	-	-	-	-	-	-	-
HCDAONAO_02436	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HCDAONAO_02437	5.05e-281	-	-	-	T	-	-	-	diguanylate cyclase
HCDAONAO_02438	1.9e-95	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HCDAONAO_02439	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HCDAONAO_02440	2.31e-277	-	-	-	-	-	-	-	-
HCDAONAO_02441	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCDAONAO_02442	2.85e-26	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCDAONAO_02443	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_02445	2.65e-289	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HCDAONAO_02446	2.43e-208	yhxD	-	-	IQ	-	-	-	KR domain
HCDAONAO_02448	1.14e-91	-	-	-	-	-	-	-	-
HCDAONAO_02449	2.88e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCDAONAO_02450	0.0	-	-	-	E	-	-	-	Amino Acid
HCDAONAO_02451	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
HCDAONAO_02452	1.71e-285	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HCDAONAO_02453	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HCDAONAO_02454	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HCDAONAO_02455	2.04e-56	-	-	-	S	-	-	-	Cupredoxin-like domain
HCDAONAO_02456	7.85e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HCDAONAO_02457	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HCDAONAO_02458	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HCDAONAO_02459	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HCDAONAO_02460	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HCDAONAO_02461	0.0	-	-	-	-	-	-	-	-
HCDAONAO_02462	2.69e-99	-	-	-	-	-	-	-	-
HCDAONAO_02463	7.81e-241	-	-	-	S	-	-	-	Cell surface protein
HCDAONAO_02464	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HCDAONAO_02465	6.57e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HCDAONAO_02466	5.83e-87	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HCDAONAO_02467	6.19e-145	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HCDAONAO_02468	4.55e-243	ynjC	-	-	S	-	-	-	Cell surface protein
HCDAONAO_02469	2.7e-131	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HCDAONAO_02470	1.47e-83	-	-	-	-	-	-	-	-
HCDAONAO_02471	1.53e-305	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HCDAONAO_02472	4.77e-155	-	-	-	-	-	-	-	-
HCDAONAO_02473	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HCDAONAO_02474	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HCDAONAO_02475	3.64e-272	-	-	-	EGP	-	-	-	Major Facilitator
HCDAONAO_02476	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HCDAONAO_02477	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HCDAONAO_02478	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HCDAONAO_02479	8.64e-97	-	-	-	L	-	-	-	Transposase DDE domain
HCDAONAO_02480	5.48e-90	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HCDAONAO_02481	3.98e-151	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCDAONAO_02482	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCDAONAO_02483	1.97e-111	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HCDAONAO_02484	2.88e-237	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HCDAONAO_02485	4.54e-202	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HCDAONAO_02486	1.29e-206	-	-	-	K	-	-	-	LysR substrate binding domain
HCDAONAO_02487	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HCDAONAO_02488	0.0	-	-	-	S	-	-	-	MucBP domain
HCDAONAO_02490	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HCDAONAO_02491	1.9e-148	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HCDAONAO_02492	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HCDAONAO_02493	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCDAONAO_02494	5.97e-85	-	-	-	-	-	-	-	-
HCDAONAO_02495	5.61e-54	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HCDAONAO_02496	7.06e-31	-	-	-	K	-	-	-	Transcriptional regulator
HCDAONAO_02497	2.08e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HCDAONAO_02498	3.05e-281	-	-	-	S	-	-	-	Membrane
HCDAONAO_02499	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HCDAONAO_02500	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HCDAONAO_02501	1.4e-57	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HCDAONAO_02502	8.95e-53	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HCDAONAO_02503	1.68e-121	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HCDAONAO_02504	1.83e-259	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HCDAONAO_02505	6.27e-104	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCDAONAO_02506	5.04e-92	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCDAONAO_02507	7.75e-153	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HCDAONAO_02509	8.91e-51	-	-	-	-	-	-	-	-
HCDAONAO_02510	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCDAONAO_02511	9.26e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HCDAONAO_02512	1.54e-269	xylR	-	-	GK	-	-	-	ROK family
HCDAONAO_02513	1.28e-56	-	-	-	-	-	-	-	-
HCDAONAO_02514	4.05e-211	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCDAONAO_02515	1.95e-114	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HCDAONAO_02516	2.54e-55	-	-	-	-	-	-	-	-
HCDAONAO_02517	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HCDAONAO_02518	8.15e-211	-	-	-	-	-	-	-	-
HCDAONAO_02519	2.36e-259	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HCDAONAO_02520	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HCDAONAO_02521	7.09e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HCDAONAO_02522	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HCDAONAO_02523	2.12e-72	-	-	-	-	-	-	-	-
HCDAONAO_02524	3.37e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HCDAONAO_02525	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HCDAONAO_02526	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HCDAONAO_02527	1.66e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HCDAONAO_02528	2.18e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HCDAONAO_02529	6.55e-272	hpk31	-	-	T	-	-	-	Histidine kinase
HCDAONAO_02530	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HCDAONAO_02531	2.3e-159	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HCDAONAO_02532	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCDAONAO_02533	2.02e-269	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCDAONAO_02534	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HCDAONAO_02535	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCDAONAO_02536	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HCDAONAO_02537	6.14e-202	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HCDAONAO_02538	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HCDAONAO_02539	3.36e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HCDAONAO_02540	6.06e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HCDAONAO_02541	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HCDAONAO_02542	5.43e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCDAONAO_02543	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HCDAONAO_02544	5.93e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
HCDAONAO_02545	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HCDAONAO_02546	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCDAONAO_02547	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCDAONAO_02548	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HCDAONAO_02549	7.25e-126	-	-	-	KT	-	-	-	response to antibiotic
HCDAONAO_02550	1.72e-69	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HCDAONAO_02551	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HCDAONAO_02552	3.77e-199	-	-	-	S	-	-	-	Putative adhesin
HCDAONAO_02553	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HCDAONAO_02554	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HCDAONAO_02555	2.6e-233	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HCDAONAO_02556	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
HCDAONAO_02557	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HCDAONAO_02558	2.51e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HCDAONAO_02559	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCDAONAO_02560	6.26e-101	-	-	-	-	-	-	-	-
HCDAONAO_02561	2.31e-195	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HCDAONAO_02562	1.44e-189	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HCDAONAO_02563	1.08e-102	-	-	-	K	-	-	-	MerR family regulatory protein
HCDAONAO_02564	1.25e-198	-	-	-	GM	-	-	-	NmrA-like family
HCDAONAO_02565	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HCDAONAO_02566	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HCDAONAO_02568	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HCDAONAO_02569	4.88e-303	-	-	-	S	-	-	-	module of peptide synthetase
HCDAONAO_02570	3.32e-135	-	-	-	-	-	-	-	-
HCDAONAO_02571	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HCDAONAO_02572	1.74e-53	-	-	-	S	-	-	-	Enterocin A Immunity
HCDAONAO_02573	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HCDAONAO_02574	1.54e-214	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HCDAONAO_02575	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HCDAONAO_02576	9.76e-83	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HCDAONAO_02577	4.78e-163	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HCDAONAO_02578	4.48e-185	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HCDAONAO_02579	1.03e-34	-	-	-	-	-	-	-	-
HCDAONAO_02580	1.21e-151	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HCDAONAO_02581	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HCDAONAO_02582	8.78e-205	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HCDAONAO_02583	3.04e-231	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HCDAONAO_02584	7.91e-249	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HCDAONAO_02585	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HCDAONAO_02586	2.49e-73	-	-	-	S	-	-	-	Enterocin A Immunity
HCDAONAO_02587	1.75e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCDAONAO_02588	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCDAONAO_02589	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCDAONAO_02590	2.5e-188	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HCDAONAO_02591	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCDAONAO_02593	1.18e-82	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCDAONAO_02594	7.91e-187	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
HCDAONAO_02595	2.74e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HCDAONAO_02596	7.66e-106	-	-	-	-	-	-	-	-
HCDAONAO_02597	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HCDAONAO_02599	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HCDAONAO_02600	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCDAONAO_02601	5.14e-227	ydbI	-	-	K	-	-	-	AI-2E family transporter
HCDAONAO_02602	9.71e-276	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HCDAONAO_02603	3.85e-76	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HCDAONAO_02604	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HCDAONAO_02605	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HCDAONAO_02606	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HCDAONAO_02607	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HCDAONAO_02608	8.03e-28	-	-	-	-	-	-	-	-
HCDAONAO_02609	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HCDAONAO_02610	1.37e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HCDAONAO_02611	1.93e-132	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HCDAONAO_02612	1.83e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HCDAONAO_02613	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HCDAONAO_02614	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HCDAONAO_02615	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HCDAONAO_02616	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
HCDAONAO_02617	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HCDAONAO_02618	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
HCDAONAO_02620	4.54e-54	-	-	-	-	-	-	-	-
HCDAONAO_02621	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HCDAONAO_02622	1.07e-124	-	-	-	V	-	-	-	VanZ like family
HCDAONAO_02623	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
HCDAONAO_02624	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HCDAONAO_02625	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCDAONAO_02626	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
HCDAONAO_02627	4.27e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
HCDAONAO_02628	3.44e-127	-	-	-	FG	-	-	-	HIT domain
HCDAONAO_02629	8.46e-50	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HCDAONAO_02630	4.29e-101	-	-	-	-	-	-	-	-
HCDAONAO_02631	1.52e-156	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HCDAONAO_02632	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HCDAONAO_02633	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HCDAONAO_02635	2.54e-159	-	-	-	S	-	-	-	YjbR
HCDAONAO_02636	2.24e-283	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HCDAONAO_02637	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HCDAONAO_02638	1.01e-255	glmS2	-	-	M	-	-	-	SIS domain
HCDAONAO_02639	2.7e-30	-	-	-	S	-	-	-	Belongs to the LOG family
HCDAONAO_02640	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HCDAONAO_02641	9.04e-317	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HCDAONAO_02642	7.59e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCDAONAO_02643	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HCDAONAO_02644	1.93e-209	-	-	-	GM	-	-	-	NmrA-like family
HCDAONAO_02645	2.71e-89	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HCDAONAO_02646	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HCDAONAO_02647	9.91e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HCDAONAO_02648	1.7e-70	-	-	-	-	-	-	-	-
HCDAONAO_02649	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HCDAONAO_02650	2.11e-82	-	-	-	-	-	-	-	-
HCDAONAO_02651	9.16e-111	-	-	-	-	-	-	-	-
HCDAONAO_02652	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HCDAONAO_02653	4.59e-74	-	-	-	-	-	-	-	-
HCDAONAO_02654	4.79e-21	-	-	-	-	-	-	-	-
HCDAONAO_02655	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HCDAONAO_02656	7.23e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HCDAONAO_02657	1.63e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HCDAONAO_02658	2.66e-155	-	-	-	S	-	-	-	membrane
HCDAONAO_02659	1.47e-144	-	-	-	S	-	-	-	VIT family
HCDAONAO_02660	2.53e-242	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HCDAONAO_02661	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HCDAONAO_02662	4.83e-98	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HCDAONAO_02663	2.47e-53	-	-	-	-	-	-	-	-
HCDAONAO_02664	8.43e-97	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HCDAONAO_02665	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HCDAONAO_02666	7.21e-35	-	-	-	-	-	-	-	-
HCDAONAO_02667	2.55e-65	-	-	-	-	-	-	-	-
HCDAONAO_02668	8.75e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HCDAONAO_02669	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HCDAONAO_02670	8.64e-97	-	-	-	L	-	-	-	Transposase DDE domain
HCDAONAO_02671	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HCDAONAO_02672	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HCDAONAO_02673	5.99e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HCDAONAO_02674	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HCDAONAO_02675	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HCDAONAO_02676	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HCDAONAO_02677	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HCDAONAO_02678	7.17e-85	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HCDAONAO_02679	1.05e-94	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HCDAONAO_02680	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HCDAONAO_02681	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HCDAONAO_02682	2.93e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HCDAONAO_02683	3.68e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HCDAONAO_02684	5.43e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HCDAONAO_02685	4.88e-117	ymdB	-	-	S	-	-	-	Macro domain protein
HCDAONAO_02686	5.31e-123	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HCDAONAO_02687	1.58e-66	-	-	-	-	-	-	-	-
HCDAONAO_02688	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HCDAONAO_02689	0.0	-	-	-	-	-	-	-	-
HCDAONAO_02690	7.89e-245	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HCDAONAO_02691	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HCDAONAO_02692	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HCDAONAO_02693	1.31e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HCDAONAO_02694	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCDAONAO_02695	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HCDAONAO_02696	4.45e-38	-	-	-	-	-	-	-	-
HCDAONAO_02697	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HCDAONAO_02698	1.88e-96	-	-	-	M	-	-	-	PFAM NLP P60 protein
HCDAONAO_02699	6.18e-71	-	-	-	-	-	-	-	-
HCDAONAO_02700	1.93e-79	-	-	-	-	-	-	-	-
HCDAONAO_02703	5.89e-231	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HCDAONAO_02704	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HCDAONAO_02705	2.05e-163	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HCDAONAO_02706	2.41e-233	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HCDAONAO_02707	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HCDAONAO_02708	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HCDAONAO_02709	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HCDAONAO_02710	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HCDAONAO_02712	8.33e-66	-	-	-	F	-	-	-	NUDIX domain
HCDAONAO_02713	1.01e-26	-	-	-	-	-	-	-	-
HCDAONAO_02714	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HCDAONAO_02715	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HCDAONAO_02716	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HCDAONAO_02717	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HCDAONAO_02718	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HCDAONAO_02719	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HCDAONAO_02720	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HCDAONAO_02721	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HCDAONAO_02722	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HCDAONAO_02723	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HCDAONAO_02724	7.83e-60	-	-	-	-	-	-	-	-
HCDAONAO_02725	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HCDAONAO_02726	1.03e-65	-	-	-	-	-	-	-	-
HCDAONAO_02727	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
HCDAONAO_02728	1.64e-282	-	-	-	S	-	-	-	associated with various cellular activities
HCDAONAO_02729	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HCDAONAO_02730	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HCDAONAO_02731	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HCDAONAO_02732	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HCDAONAO_02733	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HCDAONAO_02734	2.84e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HCDAONAO_02735	2.37e-250	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HCDAONAO_02736	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HCDAONAO_02737	2.13e-295	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HCDAONAO_02738	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HCDAONAO_02739	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HCDAONAO_02740	8.64e-97	-	-	-	L	-	-	-	Transposase DDE domain
HCDAONAO_02741	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HCDAONAO_02742	5.16e-208	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HCDAONAO_02743	6.22e-140	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HCDAONAO_02744	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HCDAONAO_02745	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HCDAONAO_02746	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HCDAONAO_02747	1.26e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HCDAONAO_02748	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HCDAONAO_02749	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HCDAONAO_02750	9.11e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HCDAONAO_02751	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HCDAONAO_02752	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HCDAONAO_02753	6.19e-284	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HCDAONAO_02754	1.43e-251	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HCDAONAO_02755	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HCDAONAO_02756	5.16e-248	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HCDAONAO_02757	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HCDAONAO_02758	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HCDAONAO_02759	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCDAONAO_02760	2.2e-173	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HCDAONAO_02761	7.89e-213	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCDAONAO_02762	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HCDAONAO_02763	1.15e-281	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCDAONAO_02764	1.02e-203	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCDAONAO_02765	8.13e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCDAONAO_02766	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HCDAONAO_02767	9.22e-211	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HCDAONAO_02768	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HCDAONAO_02769	6.17e-260	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCDAONAO_02770	4.22e-83	-	-	-	-	-	-	-	-
HCDAONAO_02771	7.54e-200	estA	-	-	S	-	-	-	Putative esterase
HCDAONAO_02772	5.44e-174	-	-	-	K	-	-	-	UTRA domain
HCDAONAO_02773	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCDAONAO_02774	3.98e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HCDAONAO_02775	1.69e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HCDAONAO_02776	2.64e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HCDAONAO_02777	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HCDAONAO_02778	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HCDAONAO_02779	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HCDAONAO_02780	1.09e-232	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCDAONAO_02781	7.04e-144	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCDAONAO_02782	1.84e-283	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HCDAONAO_02783	7.66e-137	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HCDAONAO_02784	6.19e-284	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HCDAONAO_02785	2.15e-206	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
HCDAONAO_02786	1.32e-240	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HCDAONAO_02787	1.69e-295	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HCDAONAO_02788	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HCDAONAO_02789	3.53e-100	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCDAONAO_02790	6.69e-149	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HCDAONAO_02791	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HCDAONAO_02792	1.85e-61	icaB	-	-	G	ko:K21478	-	ko00000,ko01000	Polysaccharide deacetylase
HCDAONAO_02794	2.69e-163	icaA	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyltransferases, probably involved in cell wall biogenesis
HCDAONAO_02795	8.94e-152	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HCDAONAO_02796	4.6e-291	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HCDAONAO_02797	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HCDAONAO_02798	1.22e-115	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HCDAONAO_02799	1.06e-16	-	-	-	-	-	-	-	-
HCDAONAO_02800	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HCDAONAO_02801	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HCDAONAO_02802	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HCDAONAO_02803	8.66e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HCDAONAO_02804	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HCDAONAO_02805	9.62e-19	-	-	-	-	-	-	-	-
HCDAONAO_02806	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HCDAONAO_02807	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HCDAONAO_02808	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HCDAONAO_02809	1.2e-200	is18	-	-	L	-	-	-	Integrase core domain
HCDAONAO_02811	1.97e-256	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HCDAONAO_02812	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HCDAONAO_02813	8.64e-97	-	-	-	L	-	-	-	Transposase DDE domain
HCDAONAO_02814	3.08e-265	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HCDAONAO_02815	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HCDAONAO_02816	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HCDAONAO_02817	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HCDAONAO_02818	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCDAONAO_02819	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HCDAONAO_02820	3.55e-08	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HCDAONAO_02821	6.2e-09	-	-	-	-	-	-	-	-
HCDAONAO_02822	6.69e-26	-	-	-	-	-	-	-	-
HCDAONAO_02823	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HCDAONAO_02824	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HCDAONAO_02825	5.03e-128	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HCDAONAO_02826	3.7e-133	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HCDAONAO_02827	1.32e-181	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HCDAONAO_02828	2.04e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCDAONAO_02829	6.39e-200	degV1	-	-	S	-	-	-	DegV family
HCDAONAO_02830	1.21e-72	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HCDAONAO_02831	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HCDAONAO_02833	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HCDAONAO_02834	0.0	-	-	-	-	-	-	-	-
HCDAONAO_02836	9.06e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HCDAONAO_02837	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
HCDAONAO_02838	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCDAONAO_02839	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCDAONAO_02840	2.37e-173	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HCDAONAO_02841	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCDAONAO_02842	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCDAONAO_02843	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HCDAONAO_02844	1.45e-79	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HCDAONAO_02845	4.9e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HCDAONAO_02846	4.17e-55	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
HCDAONAO_02847	3.77e-139	-	-	-	L	-	-	-	Integrase
HCDAONAO_02848	2.39e-279	-	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
HCDAONAO_02849	6.89e-162	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HCDAONAO_02850	2.05e-37	-	-	-	-	-	-	-	-
HCDAONAO_02851	2.2e-223	-	-	-	L	-	-	-	Initiator Replication protein
HCDAONAO_02852	1.02e-109	-	-	-	-	-	-	-	-
HCDAONAO_02853	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HCDAONAO_02854	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HCDAONAO_02855	6.73e-42	-	-	-	L	-	-	-	Initiator Replication protein
HCDAONAO_02856	1.1e-51	-	-	-	L	-	-	-	Initiator Replication protein
HCDAONAO_02858	3.5e-38	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
HCDAONAO_02861	3.15e-78	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HCDAONAO_02862	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HCDAONAO_02863	3.62e-137	-	-	-	L	-	-	-	Integrase
HCDAONAO_02864	8.03e-34	-	-	-	-	-	-	-	-
HCDAONAO_02865	1.7e-200	-	-	-	L	-	-	-	Initiator Replication protein
HCDAONAO_02866	1.52e-75	-	-	-	-	-	-	-	-
HCDAONAO_02867	9.18e-12	ysnF	-	-	S	-	-	-	Heat induced stress protein YflT
HCDAONAO_02868	1.72e-18	-	-	-	S	-	-	-	Class II bacteriocin
HCDAONAO_02870	3.21e-50	-	-	-	-	-	-	-	-
HCDAONAO_02871	7.24e-138	-	-	-	S	-	-	-	Plasmid replication protein
HCDAONAO_02872	2.37e-103	-	-	-	L	-	-	-	Phage integrase family
HCDAONAO_02877	1.6e-163	-	-	-	L	-	-	-	Replication protein