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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
JOHHMKPA_00001	1.75e-211	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
JOHHMKPA_00002	0.0	-	-	-	L	-	-	-	Nuclease-related domain
JOHHMKPA_00003	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JOHHMKPA_00004	2.31e-148	-	-	-	S	-	-	-	repeat protein
JOHHMKPA_00005	4.7e-163	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
JOHHMKPA_00006	4.47e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JOHHMKPA_00007	9.98e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
JOHHMKPA_00008	1.62e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
JOHHMKPA_00009	2.05e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JOHHMKPA_00010	1.22e-55	-	-	-	-	-	-	-	-
JOHHMKPA_00011	5.18e-134	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
JOHHMKPA_00012	2.32e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
JOHHMKPA_00013	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JOHHMKPA_00014	6.3e-138	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
JOHHMKPA_00015	4.01e-192	ylmH	-	-	S	-	-	-	S4 domain protein
JOHHMKPA_00016	2.42e-60	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
JOHHMKPA_00017	1.43e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
JOHHMKPA_00018	2.52e-300	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JOHHMKPA_00019	3.3e-315	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JOHHMKPA_00020	3.14e-194	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JOHHMKPA_00021	3.88e-264	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JOHHMKPA_00022	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JOHHMKPA_00023	4.43e-224	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JOHHMKPA_00024	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
JOHHMKPA_00025	6.55e-72	ftsL	-	-	D	-	-	-	Cell division protein FtsL
JOHHMKPA_00026	1.49e-223	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JOHHMKPA_00027	5.63e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
JOHHMKPA_00028	1.02e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
JOHHMKPA_00029	1.4e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
JOHHMKPA_00030	5.43e-122	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
JOHHMKPA_00031	8.27e-189	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
JOHHMKPA_00032	8.26e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
JOHHMKPA_00033	6.18e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
JOHHMKPA_00034	1.06e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
JOHHMKPA_00035	1.22e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
JOHHMKPA_00036	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JOHHMKPA_00037	2.91e-67	-	-	-	-	-	-	-	-
JOHHMKPA_00038	3.02e-166	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
JOHHMKPA_00039	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
JOHHMKPA_00040	9.25e-13	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
JOHHMKPA_00041	8.53e-59	-	-	-	-	-	-	-	-
JOHHMKPA_00042	3.33e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
JOHHMKPA_00043	4.08e-218	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
JOHHMKPA_00044	1.06e-86	-	-	-	S	-	-	-	GtrA-like protein
JOHHMKPA_00045	3.97e-57	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
JOHHMKPA_00046	6.01e-153	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
JOHHMKPA_00047	2.1e-232	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
JOHHMKPA_00048	3.48e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JOHHMKPA_00049	3.52e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
JOHHMKPA_00050	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JOHHMKPA_00051	3.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JOHHMKPA_00052	8.08e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
JOHHMKPA_00053	1.47e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
JOHHMKPA_00054	1.35e-56	-	-	-	-	-	-	-	-
JOHHMKPA_00055	9.45e-104	uspA	-	-	T	-	-	-	universal stress protein
JOHHMKPA_00056	1.18e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
JOHHMKPA_00057	5.13e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
JOHHMKPA_00058	1.59e-68	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
JOHHMKPA_00059	4.81e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
JOHHMKPA_00060	2.54e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
JOHHMKPA_00061	2.45e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
JOHHMKPA_00062	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JOHHMKPA_00063	1.48e-221	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JOHHMKPA_00064	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JOHHMKPA_00065	6.55e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JOHHMKPA_00066	2.48e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JOHHMKPA_00067	4.83e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JOHHMKPA_00068	5.87e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
JOHHMKPA_00069	5.28e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JOHHMKPA_00070	1.66e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JOHHMKPA_00071	1.24e-198	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JOHHMKPA_00072	6.6e-237	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JOHHMKPA_00073	7.02e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
JOHHMKPA_00074	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
JOHHMKPA_00077	7.95e-250	ampC	-	-	V	-	-	-	Beta-lactamase
JOHHMKPA_00078	3.26e-274	-	-	-	EGP	-	-	-	Major Facilitator
JOHHMKPA_00079	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
JOHHMKPA_00080	5.3e-137	vanZ	-	-	V	-	-	-	VanZ like family
JOHHMKPA_00081	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
JOHHMKPA_00082	0.0	yclK	-	-	T	-	-	-	Histidine kinase
JOHHMKPA_00083	4.96e-167	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
JOHHMKPA_00084	9.01e-90	-	-	-	S	-	-	-	SdpI/YhfL protein family
JOHHMKPA_00085	1.93e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
JOHHMKPA_00086	1.72e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
JOHHMKPA_00087	1.21e-127	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
JOHHMKPA_00089	1.07e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JOHHMKPA_00090	2.42e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
JOHHMKPA_00091	3.69e-30	-	-	-	-	-	-	-	-
JOHHMKPA_00092	1.94e-100	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
JOHHMKPA_00093	1.68e-55	-	-	-	-	-	-	-	-
JOHHMKPA_00094	8.19e-91	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
JOHHMKPA_00095	7.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
JOHHMKPA_00096	1.72e-222	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
JOHHMKPA_00097	5.04e-231	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
JOHHMKPA_00098	5.65e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
JOHHMKPA_00099	2.33e-120	-	-	-	S	-	-	-	VanZ like family
JOHHMKPA_00100	1.49e-130	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
JOHHMKPA_00101	3.96e-37	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JOHHMKPA_00103	4.31e-204	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
JOHHMKPA_00104	2.15e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
JOHHMKPA_00105	0.0	-	-	-	E	-	-	-	Amino acid permease
JOHHMKPA_00107	1.14e-99	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JOHHMKPA_00108	1.96e-110	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
JOHHMKPA_00109	2.64e-46	-	-	-	-	-	-	-	-
JOHHMKPA_00110	1.67e-136	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
JOHHMKPA_00111	2.21e-34	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
JOHHMKPA_00112	1.8e-34	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
JOHHMKPA_00113	1.64e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JOHHMKPA_00114	4.96e-270	-	-	-	S	-	-	-	SLAP domain
JOHHMKPA_00115	1.15e-154	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
JOHHMKPA_00116	7.18e-187	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
JOHHMKPA_00117	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JOHHMKPA_00118	4.16e-51	ynzC	-	-	S	-	-	-	UPF0291 protein
JOHHMKPA_00119	1.3e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
JOHHMKPA_00120	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
JOHHMKPA_00121	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
JOHHMKPA_00122	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
JOHHMKPA_00123	8.61e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
JOHHMKPA_00124	1.65e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
JOHHMKPA_00125	2.03e-251	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
JOHHMKPA_00126	2.21e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
JOHHMKPA_00127	1.76e-235	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JOHHMKPA_00128	5.86e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
JOHHMKPA_00129	1.22e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JOHHMKPA_00130	6.38e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JOHHMKPA_00131	3.93e-181	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
JOHHMKPA_00132	6.38e-254	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
JOHHMKPA_00133	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JOHHMKPA_00134	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JOHHMKPA_00135	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
JOHHMKPA_00136	1.19e-259	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
JOHHMKPA_00137	3.75e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
JOHHMKPA_00138	1.61e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
JOHHMKPA_00139	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JOHHMKPA_00140	1.67e-79	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JOHHMKPA_00141	1.64e-198	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JOHHMKPA_00142	5.35e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
JOHHMKPA_00143	6.02e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JOHHMKPA_00144	3.74e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JOHHMKPA_00145	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
JOHHMKPA_00146	6.87e-277	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JOHHMKPA_00147	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JOHHMKPA_00148	1.09e-226	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
JOHHMKPA_00155	7e-19	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
JOHHMKPA_00156	1.21e-16	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
JOHHMKPA_00157	1.71e-102	-	-	-	S	-	-	-	DNA binding
JOHHMKPA_00162	8.72e-07	-	-	-	-	-	-	-	-
JOHHMKPA_00163	5.23e-122	-	-	-	S	-	-	-	AntA/AntB antirepressor
JOHHMKPA_00169	2.36e-08	-	-	-	K	-	-	-	DNA-binding protein
JOHHMKPA_00173	1.11e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
JOHHMKPA_00174	3.2e-41	-	-	-	S	-	-	-	Conserved phage C-terminus (Phg_2220_C)
JOHHMKPA_00175	8.93e-64	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
JOHHMKPA_00181	5.99e-52	-	-	-	L	-	-	-	Endodeoxyribonuclease RusA
JOHHMKPA_00182	1.08e-10	-	-	-	-	-	-	-	-
JOHHMKPA_00191	1.12e-45	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
JOHHMKPA_00192	7.69e-16	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
JOHHMKPA_00193	3.14e-48	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
JOHHMKPA_00194	1.22e-24	-	-	-	S	-	-	-	Terminase-like family
JOHHMKPA_00195	3.84e-236	-	-	-	S	-	-	-	Terminase-like family
JOHHMKPA_00196	2.28e-178	-	-	-	S	ko:K09961	-	ko00000	Protein of unknown function (DUF1073)
JOHHMKPA_00197	5.89e-127	-	-	-	S	-	-	-	Phage Mu protein F like protein
JOHHMKPA_00198	1.14e-16	-	-	-	S	-	-	-	Lysin motif
JOHHMKPA_00199	2.77e-137	-	-	-	S	ko:K09960	-	ko00000	Uncharacterized protein conserved in bacteria (DUF2213)
JOHHMKPA_00200	5.09e-76	-	-	-	-	-	-	-	-
JOHHMKPA_00201	1.83e-181	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2184)
JOHHMKPA_00203	2.18e-96	-	-	-	-	-	-	-	-
JOHHMKPA_00204	1.21e-57	-	-	-	-	-	-	-	-
JOHHMKPA_00205	2.19e-75	-	-	-	-	-	-	-	-
JOHHMKPA_00206	6.43e-193	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
JOHHMKPA_00207	1.33e-73	-	-	-	-	-	-	-	-
JOHHMKPA_00210	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
JOHHMKPA_00211	1.19e-68	-	-	-	M	-	-	-	LysM domain
JOHHMKPA_00212	6.91e-61	-	-	-	-	-	-	-	-
JOHHMKPA_00213	1.57e-128	-	-	-	-	-	-	-	-
JOHHMKPA_00214	4.6e-63	-	-	-	-	-	-	-	-
JOHHMKPA_00215	2.37e-43	-	-	-	-	-	-	-	-
JOHHMKPA_00216	3.71e-154	-	-	-	S	-	-	-	Baseplate J-like protein
JOHHMKPA_00218	5.68e-211	-	-	-	D	-	-	-	nuclear chromosome segregation
JOHHMKPA_00219	8.92e-136	-	-	-	G	-	-	-	Phosphoglycerate mutase family
JOHHMKPA_00220	9.01e-115	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
JOHHMKPA_00221	1.9e-153	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
JOHHMKPA_00222	2.67e-148	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
JOHHMKPA_00224	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
JOHHMKPA_00226	1.93e-266	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
JOHHMKPA_00227	1.03e-237	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
JOHHMKPA_00228	3.01e-154	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
JOHHMKPA_00229	1.43e-186	-	-	-	K	-	-	-	SIS domain
JOHHMKPA_00230	1.36e-308	slpX	-	-	S	-	-	-	SLAP domain
JOHHMKPA_00231	6.39e-32	-	-	-	S	-	-	-	transposase or invertase
JOHHMKPA_00232	1.18e-13	-	-	-	-	-	-	-	-
JOHHMKPA_00233	4.41e-305	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
JOHHMKPA_00236	8.7e-255	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
JOHHMKPA_00237	1.15e-54	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
JOHHMKPA_00238	2.17e-232	-	-	-	-	-	-	-	-
JOHHMKPA_00239	1.87e-159	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
JOHHMKPA_00240	3.68e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
JOHHMKPA_00241	3.02e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
JOHHMKPA_00242	1.03e-261	-	-	-	M	-	-	-	Glycosyl transferases group 1
JOHHMKPA_00243	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JOHHMKPA_00244	1.91e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JOHHMKPA_00245	9.83e-261	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
JOHHMKPA_00246	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
JOHHMKPA_00247	9.16e-287	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
JOHHMKPA_00248	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
JOHHMKPA_00249	5.48e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
JOHHMKPA_00250	2.62e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
JOHHMKPA_00252	2.26e-118	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
JOHHMKPA_00253	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
JOHHMKPA_00254	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JOHHMKPA_00255	5.13e-267	camS	-	-	S	-	-	-	sex pheromone
JOHHMKPA_00256	5.42e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JOHHMKPA_00257	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JOHHMKPA_00258	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JOHHMKPA_00259	5.58e-219	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
JOHHMKPA_00260	2.61e-148	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
JOHHMKPA_00261	1.46e-75	-	-	-	-	-	-	-	-
JOHHMKPA_00262	9.92e-187	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
JOHHMKPA_00263	2.79e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
JOHHMKPA_00264	1.01e-256	flp	-	-	V	-	-	-	Beta-lactamase
JOHHMKPA_00265	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JOHHMKPA_00266	1.42e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
JOHHMKPA_00271	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
JOHHMKPA_00272	1.52e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
JOHHMKPA_00273	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
JOHHMKPA_00274	6.61e-186	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
JOHHMKPA_00275	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
JOHHMKPA_00277	4.83e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
JOHHMKPA_00278	3.77e-113	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JOHHMKPA_00279	1.24e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
JOHHMKPA_00280	9.29e-111	usp5	-	-	T	-	-	-	universal stress protein
JOHHMKPA_00281	2.58e-203	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
JOHHMKPA_00282	6.8e-175	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JOHHMKPA_00283	1.02e-154	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
JOHHMKPA_00284	1.83e-190	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
JOHHMKPA_00285	6.82e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
JOHHMKPA_00286	5.18e-109	-	-	-	-	-	-	-	-
JOHHMKPA_00287	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
JOHHMKPA_00288	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
JOHHMKPA_00289	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
JOHHMKPA_00290	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
JOHHMKPA_00291	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JOHHMKPA_00292	3.41e-132	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
JOHHMKPA_00293	2.19e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
JOHHMKPA_00294	2.31e-277	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
JOHHMKPA_00295	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
JOHHMKPA_00296	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
JOHHMKPA_00297	6.55e-97	-	-	-	-	-	-	-	-
JOHHMKPA_00298	3.75e-48	-	-	-	S	-	-	-	PFAM Archaeal ATPase
JOHHMKPA_00300	4.53e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
JOHHMKPA_00301	3.61e-60	-	-	-	-	-	-	-	-
JOHHMKPA_00302	2.77e-25	-	-	-	-	-	-	-	-
JOHHMKPA_00303	1.21e-40	-	-	-	-	-	-	-	-
JOHHMKPA_00304	1.05e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
JOHHMKPA_00305	8.38e-140	-	-	-	S	-	-	-	SLAP domain
JOHHMKPA_00306	6.35e-28	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
JOHHMKPA_00308	4.56e-191	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
JOHHMKPA_00310	3.6e-101	-	-	-	K	-	-	-	DNA-templated transcription, initiation
JOHHMKPA_00311	2.85e-54	-	-	-	-	-	-	-	-
JOHHMKPA_00313	6.62e-161	-	-	-	S	-	-	-	SLAP domain
JOHHMKPA_00315	2.09e-286	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JOHHMKPA_00316	7.32e-232	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
JOHHMKPA_00317	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
JOHHMKPA_00318	2.47e-138	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JOHHMKPA_00319	1.68e-207	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
JOHHMKPA_00320	3.99e-168	-	-	-	-	-	-	-	-
JOHHMKPA_00321	1.72e-149	-	-	-	-	-	-	-	-
JOHHMKPA_00322	4.51e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JOHHMKPA_00323	5.18e-128	-	-	-	G	-	-	-	Aldose 1-epimerase
JOHHMKPA_00324	2.92e-258	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
JOHHMKPA_00325	1.03e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JOHHMKPA_00326	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
JOHHMKPA_00327	2.6e-37	-	-	-	-	-	-	-	-
JOHHMKPA_00328	1.29e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
JOHHMKPA_00329	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JOHHMKPA_00330	6.28e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JOHHMKPA_00331	1.5e-178	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
JOHHMKPA_00332	2.63e-205	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
JOHHMKPA_00333	5.74e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
JOHHMKPA_00334	2.44e-143	-	-	-	S	-	-	-	CYTH
JOHHMKPA_00335	1.7e-147	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
JOHHMKPA_00336	1.57e-194	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JOHHMKPA_00337	7.96e-221	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
JOHHMKPA_00338	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
JOHHMKPA_00339	3.77e-122	-	-	-	S	-	-	-	SNARE associated Golgi protein
JOHHMKPA_00340	1.01e-255	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
JOHHMKPA_00341	1.99e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
JOHHMKPA_00342	2.19e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
JOHHMKPA_00343	2.12e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JOHHMKPA_00344	3.12e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
JOHHMKPA_00345	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
JOHHMKPA_00346	1.47e-284	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
JOHHMKPA_00347	5.49e-301	ymfH	-	-	S	-	-	-	Peptidase M16
JOHHMKPA_00348	1.39e-171	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
JOHHMKPA_00349	1.63e-154	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
JOHHMKPA_00350	3.92e-123	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JOHHMKPA_00351	1.17e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JOHHMKPA_00352	3.03e-293	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
JOHHMKPA_00353	1.94e-268	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
JOHHMKPA_00354	5.04e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
JOHHMKPA_00355	2.68e-314	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
JOHHMKPA_00356	9.44e-169	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
JOHHMKPA_00357	1.55e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JOHHMKPA_00358	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JOHHMKPA_00359	2.24e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JOHHMKPA_00360	8.33e-27	-	-	-	-	-	-	-	-
JOHHMKPA_00361	3.54e-230	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JOHHMKPA_00362	4.04e-203	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JOHHMKPA_00363	3.31e-239	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
JOHHMKPA_00364	3.42e-232	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JOHHMKPA_00365	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
JOHHMKPA_00366	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JOHHMKPA_00367	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
JOHHMKPA_00368	1.55e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
JOHHMKPA_00369	2.44e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
JOHHMKPA_00370	2.78e-251	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
JOHHMKPA_00371	8.59e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
JOHHMKPA_00372	1.16e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JOHHMKPA_00373	0.0	-	-	-	S	-	-	-	SH3-like domain
JOHHMKPA_00374	3.16e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_00375	4.76e-168	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
JOHHMKPA_00377	4.4e-86	-	-	-	K	-	-	-	LytTr DNA-binding domain
JOHHMKPA_00378	6.11e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
JOHHMKPA_00379	2.64e-134	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
JOHHMKPA_00380	1.56e-152	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
JOHHMKPA_00381	1.49e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
JOHHMKPA_00382	1.56e-160	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
JOHHMKPA_00383	1.46e-206	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
JOHHMKPA_00384	2.42e-33	-	-	-	-	-	-	-	-
JOHHMKPA_00385	8.07e-163	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JOHHMKPA_00386	5.69e-235	-	-	-	S	-	-	-	AAA domain
JOHHMKPA_00387	8.69e-66	-	-	-	-	-	-	-	-
JOHHMKPA_00388	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
JOHHMKPA_00389	1.11e-69	-	-	-	-	-	-	-	-
JOHHMKPA_00390	5.22e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
JOHHMKPA_00391	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JOHHMKPA_00392	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JOHHMKPA_00393	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
JOHHMKPA_00394	2.45e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JOHHMKPA_00395	2.69e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOHHMKPA_00396	1.55e-122	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
JOHHMKPA_00397	1.19e-45	-	-	-	-	-	-	-	-
JOHHMKPA_00398	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
JOHHMKPA_00399	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JOHHMKPA_00400	3.73e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
JOHHMKPA_00401	5e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
JOHHMKPA_00402	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JOHHMKPA_00403	1.05e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JOHHMKPA_00404	5.48e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
JOHHMKPA_00405	1.13e-210	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
JOHHMKPA_00406	3.52e-196	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
JOHHMKPA_00407	5.24e-187	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JOHHMKPA_00408	3.83e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JOHHMKPA_00409	2.89e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
JOHHMKPA_00410	7.66e-116	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
JOHHMKPA_00412	3.72e-111	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JOHHMKPA_00413	1.61e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JOHHMKPA_00414	9.32e-189	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
JOHHMKPA_00415	5.31e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
JOHHMKPA_00416	6.15e-36	-	-	-	-	-	-	-	-
JOHHMKPA_00417	1.08e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JOHHMKPA_00418	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JOHHMKPA_00419	1.12e-136	-	-	-	M	-	-	-	family 8
JOHHMKPA_00420	1.15e-47	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
JOHHMKPA_00421	6.31e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JOHHMKPA_00422	9.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JOHHMKPA_00423	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
JOHHMKPA_00424	1.15e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JOHHMKPA_00425	1.58e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
JOHHMKPA_00426	8.4e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
JOHHMKPA_00427	1.4e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
JOHHMKPA_00428	3.05e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JOHHMKPA_00429	4.27e-167	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
JOHHMKPA_00430	8.72e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
JOHHMKPA_00431	3.69e-171	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
JOHHMKPA_00432	3.93e-125	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
JOHHMKPA_00433	1.94e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JOHHMKPA_00434	1.28e-311	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
JOHHMKPA_00435	5.51e-46	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
JOHHMKPA_00436	4.01e-84	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
JOHHMKPA_00437	9.48e-31	-	-	-	-	-	-	-	-
JOHHMKPA_00438	6.8e-52	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
JOHHMKPA_00439	6.43e-230	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
JOHHMKPA_00440	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
JOHHMKPA_00441	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
JOHHMKPA_00442	8.74e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JOHHMKPA_00443	1.34e-22	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
JOHHMKPA_00444	6.94e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
JOHHMKPA_00445	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
JOHHMKPA_00446	1.08e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
JOHHMKPA_00447	1.74e-224	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
JOHHMKPA_00448	3.58e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JOHHMKPA_00449	1.37e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JOHHMKPA_00450	4.11e-173	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
JOHHMKPA_00451	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
JOHHMKPA_00452	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
JOHHMKPA_00453	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JOHHMKPA_00454	9e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JOHHMKPA_00455	4.34e-166	-	-	-	S	-	-	-	Peptidase family M23
JOHHMKPA_00456	5.37e-106	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
JOHHMKPA_00457	2.8e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
JOHHMKPA_00458	8.12e-196	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JOHHMKPA_00459	2.86e-307	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
JOHHMKPA_00460	1.25e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
JOHHMKPA_00461	1.33e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
JOHHMKPA_00462	1.65e-180	-	-	-	-	-	-	-	-
JOHHMKPA_00463	2.54e-176	-	-	-	-	-	-	-	-
JOHHMKPA_00464	3.85e-193	-	-	-	-	-	-	-	-
JOHHMKPA_00465	3.49e-36	-	-	-	-	-	-	-	-
JOHHMKPA_00466	1.27e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
JOHHMKPA_00467	4.01e-184	-	-	-	-	-	-	-	-
JOHHMKPA_00468	4.4e-215	-	-	-	-	-	-	-	-
JOHHMKPA_00469	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
JOHHMKPA_00470	1.28e-150	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
JOHHMKPA_00471	4.87e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JOHHMKPA_00472	6.67e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
JOHHMKPA_00473	5.87e-228	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
JOHHMKPA_00474	3.02e-173	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
JOHHMKPA_00475	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
JOHHMKPA_00476	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
JOHHMKPA_00477	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
JOHHMKPA_00478	9.62e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
JOHHMKPA_00479	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
JOHHMKPA_00480	6.91e-149	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
JOHHMKPA_00481	5.5e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JOHHMKPA_00482	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
JOHHMKPA_00483	8.47e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JOHHMKPA_00484	1.18e-139	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
JOHHMKPA_00485	1.85e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JOHHMKPA_00486	1.68e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
JOHHMKPA_00487	1.93e-308	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
JOHHMKPA_00488	9.67e-104	-	-	-	-	-	-	-	-
JOHHMKPA_00489	9.91e-150	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
JOHHMKPA_00490	7.32e-157	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
JOHHMKPA_00491	6.74e-269	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
JOHHMKPA_00492	5.83e-67	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
JOHHMKPA_00493	2.88e-113	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
JOHHMKPA_00494	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
JOHHMKPA_00495	8.59e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
JOHHMKPA_00496	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
JOHHMKPA_00497	2.14e-154	-	-	-	C	-	-	-	nitroreductase
JOHHMKPA_00498	1.76e-52	-	-	-	-	-	-	-	-
JOHHMKPA_00499	1.96e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
JOHHMKPA_00500	1.52e-103	-	-	-	-	-	-	-	-
JOHHMKPA_00501	6.89e-190	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
JOHHMKPA_00502	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
JOHHMKPA_00503	7.44e-189	-	-	-	S	-	-	-	hydrolase
JOHHMKPA_00504	1.85e-205	-	-	-	S	-	-	-	Phospholipase, patatin family
JOHHMKPA_00505	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
JOHHMKPA_00506	4.44e-174	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
JOHHMKPA_00507	2.9e-79	-	-	-	S	-	-	-	Enterocin A Immunity
JOHHMKPA_00508	3.18e-198	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
JOHHMKPA_00509	6.63e-174	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
JOHHMKPA_00510	1.01e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
JOHHMKPA_00511	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
JOHHMKPA_00512	6.36e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JOHHMKPA_00513	8.52e-215	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOHHMKPA_00514	7.29e-209	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
JOHHMKPA_00515	2.2e-308	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
JOHHMKPA_00516	3.52e-296	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
JOHHMKPA_00517	2.09e-110	-	-	-	-	-	-	-	-
JOHHMKPA_00518	1.04e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
JOHHMKPA_00519	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
JOHHMKPA_00520	4.29e-122	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
JOHHMKPA_00521	3.39e-187	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
JOHHMKPA_00522	2.8e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_00523	2.72e-60	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
JOHHMKPA_00524	5.43e-50	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
JOHHMKPA_00525	8.41e-314	-	-	-	G	-	-	-	MFS/sugar transport protein
JOHHMKPA_00526	1.72e-129	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
JOHHMKPA_00527	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
JOHHMKPA_00528	1.55e-306	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_00529	2.82e-43	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_00530	7.27e-106	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
JOHHMKPA_00531	2.05e-188	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
JOHHMKPA_00532	1.07e-165	-	-	-	F	-	-	-	glutamine amidotransferase
JOHHMKPA_00533	3.41e-312	steT	-	-	E	ko:K03294	-	ko00000	amino acid
JOHHMKPA_00534	3.97e-33	steT	-	-	E	ko:K03294	-	ko00000	amino acid
JOHHMKPA_00535	1.11e-256	steT	-	-	E	ko:K03294	-	ko00000	amino acid
JOHHMKPA_00536	1.53e-176	-	-	-	-	-	-	-	-
JOHHMKPA_00537	6.07e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
JOHHMKPA_00538	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
JOHHMKPA_00539	2.33e-230	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
JOHHMKPA_00540	6.83e-133	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
JOHHMKPA_00541	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
JOHHMKPA_00542	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
JOHHMKPA_00543	2.95e-283	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
JOHHMKPA_00544	3.06e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JOHHMKPA_00545	5.47e-151	-	-	-	-	-	-	-	-
JOHHMKPA_00546	2.83e-205	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOHHMKPA_00548	4.88e-12	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JOHHMKPA_00549	6.69e-155	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
JOHHMKPA_00551	1.64e-73	-	-	-	V	-	-	-	Abi-like protein
JOHHMKPA_00552	8.17e-84	-	-	-	K	-	-	-	Peptidase S24-like
JOHHMKPA_00559	6.66e-29	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
JOHHMKPA_00576	1.95e-220	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
JOHHMKPA_00578	1.01e-114	-	-	-	S	-	-	-	Phage portal protein
JOHHMKPA_00579	2.62e-57	-	-	-	S	-	-	-	Clp protease
JOHHMKPA_00580	1.3e-98	-	-	-	S	-	-	-	Phage capsid family
JOHHMKPA_00583	1.94e-38	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
JOHHMKPA_00588	1.62e-233	-	-	-	D	-	-	-	domain protein
JOHHMKPA_00590	2.88e-203	-	-	-	S	-	-	-	Phage minor structural protein
JOHHMKPA_00600	3.09e-22	-	-	-	-	-	-	-	-
JOHHMKPA_00601	1.24e-125	-	-	-	M	-	-	-	hydrolase, family 25
JOHHMKPA_00602	6.57e-141	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JOHHMKPA_00603	2e-149	-	-	-	S	-	-	-	Peptidase family M23
JOHHMKPA_00605	4.4e-142	-	-	-	S	-	-	-	Baseplate J-like protein
JOHHMKPA_00606	1.55e-40	-	-	-	-	-	-	-	-
JOHHMKPA_00607	1.01e-49	-	-	-	-	-	-	-	-
JOHHMKPA_00608	1.63e-128	-	-	-	-	-	-	-	-
JOHHMKPA_00609	9.82e-61	-	-	-	-	-	-	-	-
JOHHMKPA_00610	7.64e-54	-	-	-	M	-	-	-	LysM domain
JOHHMKPA_00611	6.89e-222	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
JOHHMKPA_00614	8.17e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
JOHHMKPA_00617	5.56e-22	-	-	-	-	-	-	-	-
JOHHMKPA_00618	4.47e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4054)
JOHHMKPA_00620	8.98e-25	-	-	-	-	-	-	-	-
JOHHMKPA_00621	7.53e-73	-	-	-	S	ko:K09960	-	ko00000	Uncharacterized protein conserved in bacteria (DUF2213)
JOHHMKPA_00622	9.61e-28	-	-	-	S	-	-	-	Lysin motif
JOHHMKPA_00623	4.71e-70	-	-	-	S	-	-	-	Phage Mu protein F like protein
JOHHMKPA_00624	1.64e-110	-	-	-	S	ko:K09961	-	ko00000	Protein of unknown function (DUF1073)
JOHHMKPA_00625	4.27e-234	-	-	-	S	-	-	-	Terminase-like family
JOHHMKPA_00628	9.77e-27	-	-	-	S	-	-	-	N-methyltransferase activity
JOHHMKPA_00636	1.72e-48	-	-	-	S	-	-	-	VRR_NUC
JOHHMKPA_00638	1.54e-86	-	-	-	S	-	-	-	ORF6C domain
JOHHMKPA_00643	9.64e-54	-	-	-	Q	-	-	-	methyltransferase
JOHHMKPA_00649	5.95e-24	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
JOHHMKPA_00651	1.36e-13	xre	-	-	K	-	-	-	sequence-specific DNA binding
JOHHMKPA_00653	4.49e-55	-	-	-	S	-	-	-	ERF superfamily
JOHHMKPA_00654	1.13e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
JOHHMKPA_00662	6.19e-16	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
JOHHMKPA_00663	5.84e-21	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
JOHHMKPA_00665	3.93e-05	-	-	-	-	-	-	-	-
JOHHMKPA_00666	2.73e-112	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
JOHHMKPA_00667	6.38e-59	-	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
JOHHMKPA_00668	1.19e-97	-	-	-	C	-	-	-	Aldo keto reductase
JOHHMKPA_00669	3.83e-231	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
JOHHMKPA_00670	5.51e-284	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
JOHHMKPA_00671	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
JOHHMKPA_00672	7.1e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
JOHHMKPA_00673	1.8e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JOHHMKPA_00674	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JOHHMKPA_00675	3.8e-80	-	-	-	-	-	-	-	-
JOHHMKPA_00676	4.8e-224	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
JOHHMKPA_00677	1.3e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JOHHMKPA_00678	5.26e-15	-	-	-	-	-	-	-	-
JOHHMKPA_00680	9.28e-317	-	-	-	S	-	-	-	Putative threonine/serine exporter
JOHHMKPA_00681	1.05e-226	citR	-	-	K	-	-	-	Putative sugar-binding domain
JOHHMKPA_00682	2.41e-66	-	-	-	-	-	-	-	-
JOHHMKPA_00683	7.91e-14	-	-	-	-	-	-	-	-
JOHHMKPA_00684	8.1e-87	-	-	-	S	-	-	-	Domain of unknown function DUF1828
JOHHMKPA_00685	5.38e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
JOHHMKPA_00686	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_00687	2.58e-189	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
JOHHMKPA_00688	9.9e-30	-	-	-	-	-	-	-	-
JOHHMKPA_00689	1.24e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
JOHHMKPA_00690	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
JOHHMKPA_00691	1.79e-214	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
JOHHMKPA_00692	1.6e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
JOHHMKPA_00693	5.17e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
JOHHMKPA_00694	5.95e-197	-	-	-	I	-	-	-	Alpha/beta hydrolase family
JOHHMKPA_00695	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
JOHHMKPA_00696	5.26e-171	-	-	-	H	-	-	-	Aldolase/RraA
JOHHMKPA_00697	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
JOHHMKPA_00698	1.66e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
JOHHMKPA_00699	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
JOHHMKPA_00700	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
JOHHMKPA_00701	1.7e-117	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
JOHHMKPA_00702	3.87e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JOHHMKPA_00703	2.16e-205	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
JOHHMKPA_00704	5.41e-225	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
JOHHMKPA_00705	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
JOHHMKPA_00706	1.86e-117	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JOHHMKPA_00707	8.21e-228	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JOHHMKPA_00708	2.41e-39	-	-	-	-	-	-	-	-
JOHHMKPA_00711	4.82e-144	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
JOHHMKPA_00712	1.25e-94	-	-	-	K	-	-	-	Helix-turn-helix domain
JOHHMKPA_00714	6.66e-27	-	-	-	S	-	-	-	CAAX protease self-immunity
JOHHMKPA_00715	2.67e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
JOHHMKPA_00717	4.11e-124	potE	-	-	E	-	-	-	thought to be involved in transport amino acids across the membrane
JOHHMKPA_00719	2.23e-189	-	-	-	S	-	-	-	Putative ABC-transporter type IV
JOHHMKPA_00721	5.61e-38	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JOHHMKPA_00722	0.0	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JOHHMKPA_00723	1.03e-82	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
JOHHMKPA_00724	3.26e-292	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
JOHHMKPA_00725	4.65e-120	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
JOHHMKPA_00726	8.87e-226	ydbI	-	-	K	-	-	-	AI-2E family transporter
JOHHMKPA_00727	3.93e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
JOHHMKPA_00728	2.55e-26	-	-	-	-	-	-	-	-
JOHHMKPA_00729	1.59e-315	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
JOHHMKPA_00730	8.64e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_00731	4.76e-168	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
JOHHMKPA_00732	3.35e-223	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
JOHHMKPA_00733	7.75e-170	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
JOHHMKPA_00734	4.17e-201	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
JOHHMKPA_00735	5.74e-206	yvgN	-	-	C	-	-	-	Aldo keto reductase
JOHHMKPA_00736	0.0	fusA1	-	-	J	-	-	-	elongation factor G
JOHHMKPA_00737	3.16e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
JOHHMKPA_00738	1.07e-179	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
JOHHMKPA_00739	9.62e-247	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOHHMKPA_00740	1.44e-07	-	-	-	S	-	-	-	YSIRK type signal peptide
JOHHMKPA_00743	5.73e-201	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
JOHHMKPA_00744	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
JOHHMKPA_00745	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
JOHHMKPA_00746	1.36e-260	pbpX	-	-	V	-	-	-	Beta-lactamase
JOHHMKPA_00747	1.69e-117	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
JOHHMKPA_00748	1.68e-55	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
JOHHMKPA_00749	2.49e-63	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
JOHHMKPA_00750	5.71e-263	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
JOHHMKPA_00751	0.0	cadA	-	-	P	-	-	-	P-type ATPase
JOHHMKPA_00752	3.41e-107	ykuL	-	-	S	-	-	-	(CBS) domain
JOHHMKPA_00753	5.11e-265	-	-	-	S	-	-	-	Membrane
JOHHMKPA_00754	1.42e-58	-	-	-	-	-	-	-	-
JOHHMKPA_00755	1.3e-26	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
JOHHMKPA_00756	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOHHMKPA_00757	2.95e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
JOHHMKPA_00758	4.98e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOHHMKPA_00759	6.8e-316	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JOHHMKPA_00760	1.97e-227	pbpX2	-	-	V	-	-	-	Beta-lactamase
JOHHMKPA_00761	1.02e-171	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
JOHHMKPA_00762	1.34e-183	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
JOHHMKPA_00763	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
JOHHMKPA_00764	1.96e-49	-	-	-	-	-	-	-	-
JOHHMKPA_00765	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
JOHHMKPA_00766	1.68e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_00767	3.09e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOHHMKPA_00768	7.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
JOHHMKPA_00769	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
JOHHMKPA_00770	5.08e-149	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
JOHHMKPA_00771	2.58e-310	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
JOHHMKPA_00772	5.27e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
JOHHMKPA_00773	6.36e-173	-	-	-	S	-	-	-	PFAM Archaeal ATPase
JOHHMKPA_00774	1.95e-221	-	-	-	V	-	-	-	HNH endonuclease
JOHHMKPA_00776	6.65e-179	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
JOHHMKPA_00777	6.45e-291	-	-	-	E	-	-	-	amino acid
JOHHMKPA_00778	5.12e-242	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
JOHHMKPA_00779	1.84e-263	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
JOHHMKPA_00782	1.35e-238	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JOHHMKPA_00783	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JOHHMKPA_00784	7.13e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JOHHMKPA_00785	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
JOHHMKPA_00786	3.4e-93	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
JOHHMKPA_00787	8.08e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JOHHMKPA_00788	1.17e-143	-	-	-	-	-	-	-	-
JOHHMKPA_00790	7.04e-145	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
JOHHMKPA_00791	4.07e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
JOHHMKPA_00792	1.5e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
JOHHMKPA_00793	4.57e-135	-	-	-	S	ko:K06872	-	ko00000	TPM domain
JOHHMKPA_00794	1.71e-173	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
JOHHMKPA_00795	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
JOHHMKPA_00796	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JOHHMKPA_00797	2.72e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
JOHHMKPA_00798	5.17e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JOHHMKPA_00799	8.93e-194	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JOHHMKPA_00800	9.99e-53	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
JOHHMKPA_00801	2.05e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
JOHHMKPA_00802	1.81e-307	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JOHHMKPA_00803	5.52e-113	-	-	-	-	-	-	-	-
JOHHMKPA_00804	0.0	-	-	-	S	-	-	-	SLAP domain
JOHHMKPA_00805	5.4e-226	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JOHHMKPA_00806	1.37e-219	-	-	-	GK	-	-	-	ROK family
JOHHMKPA_00807	1.03e-55	-	-	-	-	-	-	-	-
JOHHMKPA_00808	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
JOHHMKPA_00809	1.75e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
JOHHMKPA_00810	2.83e-90	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JOHHMKPA_00811	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JOHHMKPA_00812	1.89e-312	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JOHHMKPA_00813	7.28e-97	-	-	-	K	-	-	-	acetyltransferase
JOHHMKPA_00814	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
JOHHMKPA_00815	2.07e-196	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
JOHHMKPA_00816	7.15e-295	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
JOHHMKPA_00817	9.63e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JOHHMKPA_00818	1.1e-54	-	-	-	K	-	-	-	Helix-turn-helix
JOHHMKPA_00819	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
JOHHMKPA_00820	1.66e-121	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
JOHHMKPA_00821	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
JOHHMKPA_00822	4.2e-249	pbpX1	-	-	V	-	-	-	Beta-lactamase
JOHHMKPA_00823	2.48e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JOHHMKPA_00824	9.03e-277	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
JOHHMKPA_00825	6.89e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JOHHMKPA_00826	3.66e-225	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JOHHMKPA_00827	3.29e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JOHHMKPA_00828	8.62e-105	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JOHHMKPA_00829	1.39e-312	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JOHHMKPA_00830	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
JOHHMKPA_00831	1.79e-245	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JOHHMKPA_00832	1.27e-220	potE	-	-	E	-	-	-	Amino Acid
JOHHMKPA_00833	2.58e-48	potE	-	-	E	-	-	-	Amino Acid
JOHHMKPA_00834	1.59e-136	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
JOHHMKPA_00835	3.04e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JOHHMKPA_00836	2.49e-282	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JOHHMKPA_00837	5.76e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JOHHMKPA_00838	2.21e-190	-	-	-	-	-	-	-	-
JOHHMKPA_00839	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JOHHMKPA_00840	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JOHHMKPA_00841	3.64e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
JOHHMKPA_00842	2.57e-226	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
JOHHMKPA_00843	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
JOHHMKPA_00844	2.7e-126	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
JOHHMKPA_00845	1.42e-244	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
JOHHMKPA_00846	7.07e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JOHHMKPA_00847	5.21e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
JOHHMKPA_00848	9.94e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
JOHHMKPA_00849	3.91e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
JOHHMKPA_00850	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
JOHHMKPA_00851	2.79e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JOHHMKPA_00852	5.22e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
JOHHMKPA_00853	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JOHHMKPA_00854	5.05e-74	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
JOHHMKPA_00855	5.12e-199	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
JOHHMKPA_00856	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
JOHHMKPA_00857	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
JOHHMKPA_00858	8.39e-195	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
JOHHMKPA_00859	2.52e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
JOHHMKPA_00860	3.07e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JOHHMKPA_00861	2.85e-153	-	-	-	-	-	-	-	-
JOHHMKPA_00862	3.23e-98	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
JOHHMKPA_00863	8.04e-190	-	-	-	S	-	-	-	hydrolase
JOHHMKPA_00864	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JOHHMKPA_00865	2.76e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
JOHHMKPA_00866	2.13e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JOHHMKPA_00867	3.46e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
JOHHMKPA_00868	3.69e-170	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
JOHHMKPA_00869	8.77e-173	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
JOHHMKPA_00870	1.25e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
JOHHMKPA_00871	2.84e-208	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
JOHHMKPA_00872	1.51e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
JOHHMKPA_00873	4.82e-113	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
JOHHMKPA_00874	1.1e-232	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
JOHHMKPA_00875	1.64e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JOHHMKPA_00876	2.81e-200	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
JOHHMKPA_00877	3.07e-124	-	-	-	-	-	-	-	-
JOHHMKPA_00878	1.18e-253	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
JOHHMKPA_00879	5.46e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JOHHMKPA_00880	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
JOHHMKPA_00881	2.86e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JOHHMKPA_00882	9.26e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
JOHHMKPA_00884	0.0	-	-	-	-	-	-	-	-
JOHHMKPA_00885	0.0	ycaM	-	-	E	-	-	-	amino acid
JOHHMKPA_00886	1.43e-178	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
JOHHMKPA_00887	7.65e-101	-	-	-	K	-	-	-	MerR HTH family regulatory protein
JOHHMKPA_00888	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
JOHHMKPA_00889	4.64e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
JOHHMKPA_00891	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
JOHHMKPA_00892	5.24e-194	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOHHMKPA_00893	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
JOHHMKPA_00894	7.95e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
JOHHMKPA_00895	2.14e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
JOHHMKPA_00896	2.11e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JOHHMKPA_00897	7.98e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
JOHHMKPA_00898	2.78e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JOHHMKPA_00899	7.19e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JOHHMKPA_00900	1.97e-248	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JOHHMKPA_00901	1.53e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JOHHMKPA_00902	6.44e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
JOHHMKPA_00903	7.22e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
JOHHMKPA_00904	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
JOHHMKPA_00905	2.19e-100	-	-	-	S	-	-	-	ASCH
JOHHMKPA_00906	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
JOHHMKPA_00907	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
JOHHMKPA_00908	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JOHHMKPA_00909	4.41e-220	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JOHHMKPA_00910	1.06e-308	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JOHHMKPA_00911	1.98e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
JOHHMKPA_00912	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
JOHHMKPA_00913	1.71e-208	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JOHHMKPA_00914	4.33e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
JOHHMKPA_00915	3.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
JOHHMKPA_00916	2.2e-41	-	-	-	-	-	-	-	-
JOHHMKPA_00917	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
JOHHMKPA_00918	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
JOHHMKPA_00919	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
JOHHMKPA_00920	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JOHHMKPA_00921	3.69e-233	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JOHHMKPA_00922	1.04e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JOHHMKPA_00923	7.02e-245	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
JOHHMKPA_00924	3.27e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
JOHHMKPA_00925	1.53e-218	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
JOHHMKPA_00926	3.06e-181	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
JOHHMKPA_00927	7.65e-65	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JOHHMKPA_00928	3.7e-164	-	-	-	S	-	-	-	SLAP domain
JOHHMKPA_00929	1.75e-120	-	-	-	-	-	-	-	-
JOHHMKPA_00931	7.04e-159	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
JOHHMKPA_00932	2.07e-203	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
JOHHMKPA_00933	1.55e-201	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOHHMKPA_00934	1.49e-178	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
JOHHMKPA_00935	2.22e-60	hupB2	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JOHHMKPA_00936	2.74e-69	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
JOHHMKPA_00937	9.43e-52	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
JOHHMKPA_00938	7.04e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
JOHHMKPA_00939	0.0	-	-	-	S	-	-	-	membrane
JOHHMKPA_00940	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
JOHHMKPA_00941	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
JOHHMKPA_00942	7.92e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JOHHMKPA_00943	9.32e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
JOHHMKPA_00944	1e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
JOHHMKPA_00945	4.95e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
JOHHMKPA_00946	1.82e-214	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JOHHMKPA_00947	2.05e-286	ynbB	-	-	P	-	-	-	aluminum resistance
JOHHMKPA_00948	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
JOHHMKPA_00949	9.64e-219	-	-	-	-	-	-	-	-
JOHHMKPA_00950	1.21e-204	-	-	-	-	-	-	-	-
JOHHMKPA_00952	3.96e-19	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
JOHHMKPA_00953	1.92e-42	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
JOHHMKPA_00955	6.79e-45	-	-	-	-	-	-	-	-
JOHHMKPA_00956	3e-271	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
JOHHMKPA_00957	1.22e-202	-	-	-	S	-	-	-	interspecies interaction between organisms
JOHHMKPA_00958	1.28e-09	-	-	-	S	-	-	-	PFAM HicB family
JOHHMKPA_00959	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
JOHHMKPA_00961	4.23e-46	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
JOHHMKPA_00962	1.5e-64	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
JOHHMKPA_00963	0.0	-	-	-	E	-	-	-	Amino acid permease
JOHHMKPA_00964	2.14e-234	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
JOHHMKPA_00965	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
JOHHMKPA_00966	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
JOHHMKPA_00967	2.14e-231	-	-	-	M	-	-	-	CHAP domain
JOHHMKPA_00968	2.79e-102	-	-	-	-	-	-	-	-
JOHHMKPA_00969	1.06e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JOHHMKPA_00970	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JOHHMKPA_00971	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JOHHMKPA_00972	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JOHHMKPA_00973	3.89e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JOHHMKPA_00974	1.39e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JOHHMKPA_00975	7.58e-69	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
JOHHMKPA_00976	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JOHHMKPA_00977	6.15e-268	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JOHHMKPA_00978	3.16e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
JOHHMKPA_00979	1.26e-303	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JOHHMKPA_00980	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JOHHMKPA_00981	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
JOHHMKPA_00982	9.37e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JOHHMKPA_00983	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
JOHHMKPA_00984	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JOHHMKPA_00985	5.37e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
JOHHMKPA_00986	2.34e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JOHHMKPA_00987	5.62e-95	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
JOHHMKPA_00988	4.13e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
JOHHMKPA_00989	8.12e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JOHHMKPA_00990	1.55e-29	-	-	-	-	-	-	-	-
JOHHMKPA_00991	8.34e-116	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_00992	4.03e-75	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
JOHHMKPA_00993	3.85e-97	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
JOHHMKPA_00994	9.69e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
JOHHMKPA_00995	2.56e-179	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
JOHHMKPA_00996	6.64e-94	-	-	-	-	-	-	-	-
JOHHMKPA_00997	1.06e-159	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
JOHHMKPA_00998	9.85e-154	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
JOHHMKPA_00999	1.15e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JOHHMKPA_01000	3.08e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
JOHHMKPA_01001	3.63e-221	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
JOHHMKPA_01002	8.8e-262	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
JOHHMKPA_01003	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
JOHHMKPA_01004	4.57e-232	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
JOHHMKPA_01005	1.97e-255	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
JOHHMKPA_01006	5.9e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
JOHHMKPA_01007	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JOHHMKPA_01008	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_01009	5.14e-248	-	-	-	S	-	-	-	DUF218 domain
JOHHMKPA_01010	3.43e-155	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
JOHHMKPA_01011	8.6e-141	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
JOHHMKPA_01012	3.62e-202	-	-	-	EGP	-	-	-	Major facilitator Superfamily
JOHHMKPA_01013	1.05e-67	-	-	-	-	-	-	-	-
JOHHMKPA_01014	1.91e-200	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
JOHHMKPA_01015	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
JOHHMKPA_01016	8.06e-08	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
JOHHMKPA_01018	9.92e-152	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
JOHHMKPA_01019	2.91e-140	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
JOHHMKPA_01020	2.22e-184	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
JOHHMKPA_01021	5.61e-160	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
JOHHMKPA_01022	5.52e-187	epsB	-	-	M	-	-	-	biosynthesis protein
JOHHMKPA_01023	8.14e-241	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
JOHHMKPA_01025	6.72e-285	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JOHHMKPA_01026	1.26e-223	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
JOHHMKPA_01027	3.01e-54	-	-	-	-	-	-	-	-
JOHHMKPA_01028	1.73e-167	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
JOHHMKPA_01029	1.28e-174	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
JOHHMKPA_01030	1.47e-114	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
JOHHMKPA_01031	4.26e-115	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
JOHHMKPA_01032	4.52e-56	-	-	-	-	-	-	-	-
JOHHMKPA_01033	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
JOHHMKPA_01034	8.77e-144	-	-	-	-	-	-	-	-
JOHHMKPA_01035	1.29e-281	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
JOHHMKPA_01036	4.75e-101	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
JOHHMKPA_01037	1.96e-226	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOHHMKPA_01038	1.16e-101	-	-	-	-	-	-	-	-
JOHHMKPA_01039	1.58e-143	-	-	-	S	-	-	-	Peptidase_C39 like family
JOHHMKPA_01040	7.36e-109	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
JOHHMKPA_01041	7.35e-174	-	-	-	S	-	-	-	Putative threonine/serine exporter
JOHHMKPA_01042	0.0	-	-	-	S	-	-	-	ABC transporter
JOHHMKPA_01043	2.52e-76	-	-	-	-	-	-	-	-
JOHHMKPA_01044	8.69e-93	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
JOHHMKPA_01045	5.49e-46	-	-	-	-	-	-	-	-
JOHHMKPA_01046	7.2e-40	-	-	-	-	-	-	-	-
JOHHMKPA_01047	2.33e-143	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
JOHHMKPA_01048	5.74e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
JOHHMKPA_01049	2.63e-50	-	-	-	-	-	-	-	-
JOHHMKPA_01050	1.25e-143	-	-	-	K	-	-	-	WHG domain
JOHHMKPA_01051	3.41e-125	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
JOHHMKPA_01052	2.58e-126	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
JOHHMKPA_01053	9.48e-194	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
JOHHMKPA_01054	5.24e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
JOHHMKPA_01056	2.99e-75	cvpA	-	-	S	-	-	-	Colicin V production protein
JOHHMKPA_01057	2.12e-86	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
JOHHMKPA_01058	3.66e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
JOHHMKPA_01059	5.86e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
JOHHMKPA_01060	4.99e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
JOHHMKPA_01061	4.28e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
JOHHMKPA_01062	1.1e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
JOHHMKPA_01063	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JOHHMKPA_01064	3.93e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
JOHHMKPA_01065	1.22e-190	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_01066	1.68e-179	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_01067	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
JOHHMKPA_01069	8.32e-157	vanR	-	-	K	-	-	-	response regulator
JOHHMKPA_01070	9.28e-271	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
JOHHMKPA_01071	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JOHHMKPA_01072	7.79e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
JOHHMKPA_01073	6.94e-70	-	-	-	S	-	-	-	Enterocin A Immunity
JOHHMKPA_01074	1.95e-45	-	-	-	-	-	-	-	-
JOHHMKPA_01075	1.07e-35	-	-	-	-	-	-	-	-
JOHHMKPA_01076	4.48e-34	-	-	-	-	-	-	-	-
JOHHMKPA_01077	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
JOHHMKPA_01078	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
JOHHMKPA_01079	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
JOHHMKPA_01080	1.89e-23	-	-	-	-	-	-	-	-
JOHHMKPA_01081	6.42e-73	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
JOHHMKPA_01082	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
JOHHMKPA_01083	2.69e-156	phoB	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
JOHHMKPA_01084	6.07e-138	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
JOHHMKPA_01085	4.66e-179	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JOHHMKPA_01086	8.63e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
JOHHMKPA_01087	8.73e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
JOHHMKPA_01088	9.14e-187	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
JOHHMKPA_01089	4.84e-42	-	-	-	-	-	-	-	-
JOHHMKPA_01090	3.11e-256	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
JOHHMKPA_01091	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
JOHHMKPA_01092	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
JOHHMKPA_01093	1.39e-156	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
JOHHMKPA_01094	6.75e-216	-	-	-	K	-	-	-	LysR substrate binding domain
JOHHMKPA_01095	1.88e-108	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
JOHHMKPA_01096	1.41e-51	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
JOHHMKPA_01097	3.01e-294	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
JOHHMKPA_01098	1.03e-206	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
JOHHMKPA_01099	1.38e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
JOHHMKPA_01100	8.7e-166	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
JOHHMKPA_01101	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JOHHMKPA_01102	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
JOHHMKPA_01103	9.83e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
JOHHMKPA_01104	7.25e-309	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
JOHHMKPA_01105	4.66e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JOHHMKPA_01106	1.19e-43	-	-	-	S	-	-	-	reductase
JOHHMKPA_01107	2.98e-50	-	-	-	S	-	-	-	reductase
JOHHMKPA_01108	6.32e-41	-	-	-	S	-	-	-	reductase
JOHHMKPA_01109	1.83e-190	yxeH	-	-	S	-	-	-	hydrolase
JOHHMKPA_01110	1.14e-230	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOHHMKPA_01111	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
JOHHMKPA_01112	1.58e-140	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
JOHHMKPA_01113	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JOHHMKPA_01114	1.88e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JOHHMKPA_01115	0.0	oatA	-	-	I	-	-	-	Acyltransferase
JOHHMKPA_01116	6.82e-223	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JOHHMKPA_01117	1.18e-183	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
JOHHMKPA_01118	3.57e-47	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
JOHHMKPA_01119	5.14e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
JOHHMKPA_01120	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
JOHHMKPA_01121	1.25e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
JOHHMKPA_01122	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
JOHHMKPA_01123	5.46e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JOHHMKPA_01124	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
JOHHMKPA_01125	4.41e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
JOHHMKPA_01126	5.77e-214	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
JOHHMKPA_01127	4.62e-81	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOHHMKPA_01128	1.81e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JOHHMKPA_01129	7.57e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JOHHMKPA_01130	4.65e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
JOHHMKPA_01131	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
JOHHMKPA_01132	1.21e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
JOHHMKPA_01133	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
JOHHMKPA_01134	8.43e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
JOHHMKPA_01135	1.27e-290	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
JOHHMKPA_01136	0.0	yhaN	-	-	L	-	-	-	AAA domain
JOHHMKPA_01137	4.53e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
JOHHMKPA_01139	9.67e-33	-	-	-	S	-	-	-	Domain of unknown function DUF1829
JOHHMKPA_01140	0.0	-	-	-	-	-	-	-	-
JOHHMKPA_01141	5.74e-96	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
JOHHMKPA_01142	3.12e-196	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JOHHMKPA_01143	1.2e-41	-	-	-	-	-	-	-	-
JOHHMKPA_01144	1.61e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
JOHHMKPA_01145	3.67e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_01146	1.63e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
JOHHMKPA_01147	2.16e-163	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JOHHMKPA_01149	1.35e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
JOHHMKPA_01150	8.78e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JOHHMKPA_01151	2.59e-313	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
JOHHMKPA_01152	4.65e-278	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
JOHHMKPA_01153	2.04e-226	-	-	-	S	-	-	-	SLAP domain
JOHHMKPA_01154	0.0	-	-	-	M	-	-	-	Peptidase family M1 domain
JOHHMKPA_01155	6.72e-66	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
JOHHMKPA_01156	4.83e-104	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JOHHMKPA_01157	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JOHHMKPA_01158	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
JOHHMKPA_01159	3.87e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
JOHHMKPA_01160	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
JOHHMKPA_01161	5.56e-217	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
JOHHMKPA_01162	2.26e-215	degV1	-	-	S	-	-	-	DegV family
JOHHMKPA_01163	1.23e-170	-	-	-	V	-	-	-	ABC transporter transmembrane region
JOHHMKPA_01164	4.76e-213	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
JOHHMKPA_01165	3.81e-18	-	-	-	S	-	-	-	CsbD-like
JOHHMKPA_01166	2.26e-31	-	-	-	S	-	-	-	Transglycosylase associated protein
JOHHMKPA_01167	1.37e-287	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
JOHHMKPA_01168	3.92e-153	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
JOHHMKPA_01171	7.2e-84	-	-	-	-	-	-	-	-
JOHHMKPA_01172	8.29e-67	-	-	-	-	-	-	-	-
JOHHMKPA_01173	1.36e-171	-	-	-	D	-	-	-	Ftsk spoiiie family protein
JOHHMKPA_01174	5.28e-180	-	-	-	S	-	-	-	Replication initiation factor
JOHHMKPA_01175	1.33e-72	-	-	-	-	-	-	-	-
JOHHMKPA_01176	4.04e-36	-	-	-	-	-	-	-	-
JOHHMKPA_01177	3.5e-280	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
JOHHMKPA_01179	9.75e-80	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
JOHHMKPA_01180	8.25e-65	-	-	-	V	ko:K01990,ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
JOHHMKPA_01182	6.56e-86	sagB	-	-	C	-	-	-	Nitroreductase family
JOHHMKPA_01184	4.04e-55	sagD	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
JOHHMKPA_01185	1.01e-38	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
JOHHMKPA_01186	2.27e-71	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
JOHHMKPA_01187	7.26e-35	-	-	-	S	-	-	-	Protein conserved in bacteria
JOHHMKPA_01188	1.09e-74	-	-	-	-	-	-	-	-
JOHHMKPA_01189	6.77e-111	-	-	-	-	-	-	-	-
JOHHMKPA_01190	0.0	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
JOHHMKPA_01191	1.84e-238	-	-	-	S	-	-	-	DUF218 domain
JOHHMKPA_01192	9.07e-143	-	-	-	-	-	-	-	-
JOHHMKPA_01193	1.32e-137	-	-	-	-	-	-	-	-
JOHHMKPA_01194	3.75e-178	yicL	-	-	EG	-	-	-	EamA-like transporter family
JOHHMKPA_01195	3.18e-209	-	-	-	EG	-	-	-	EamA-like transporter family
JOHHMKPA_01196	4.48e-206	-	-	-	EG	-	-	-	EamA-like transporter family
JOHHMKPA_01197	5.51e-47	-	-	-	-	-	-	-	-
JOHHMKPA_01198	1.03e-07	-	-	-	-	-	-	-	-
JOHHMKPA_01199	1.02e-200	-	-	-	-	-	-	-	-
JOHHMKPA_01202	8.6e-108	-	-	-	M	-	-	-	NlpC/P60 family
JOHHMKPA_01203	1.51e-168	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
JOHHMKPA_01204	6.69e-84	-	-	-	L	-	-	-	RelB antitoxin
JOHHMKPA_01205	1.83e-91	-	-	-	V	-	-	-	ABC transporter transmembrane region
JOHHMKPA_01206	3.65e-285	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
JOHHMKPA_01207	5.63e-171	-	-	-	V	-	-	-	ABC transporter transmembrane region
JOHHMKPA_01208	1.74e-248	-	-	-	G	-	-	-	Transmembrane secretion effector
JOHHMKPA_01209	3.66e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
JOHHMKPA_01210	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JOHHMKPA_01211	7.48e-188	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
JOHHMKPA_01212	9.04e-230	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
JOHHMKPA_01213	1.85e-141	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JOHHMKPA_01214	7.86e-138	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
JOHHMKPA_01215	5.02e-180	blpT	-	-	-	-	-	-	-
JOHHMKPA_01218	7.87e-30	-	-	-	-	-	-	-	-
JOHHMKPA_01219	4.74e-107	-	-	-	-	-	-	-	-
JOHHMKPA_01220	6.32e-42	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
JOHHMKPA_01221	2.52e-32	-	-	-	-	-	-	-	-
JOHHMKPA_01222	3.41e-88	-	-	-	-	-	-	-	-
JOHHMKPA_01223	3.09e-212	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_01224	6.39e-279	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
JOHHMKPA_01225	3.14e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
JOHHMKPA_01226	2.18e-215	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
JOHHMKPA_01227	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
JOHHMKPA_01228	4.47e-56	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
JOHHMKPA_01229	9.9e-209	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
JOHHMKPA_01230	1.63e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
JOHHMKPA_01231	1.59e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
JOHHMKPA_01232	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
JOHHMKPA_01233	6.6e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JOHHMKPA_01234	2.04e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
JOHHMKPA_01235	0.000868	-	-	-	-	-	-	-	-
JOHHMKPA_01236	1.13e-35	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
JOHHMKPA_01237	6.12e-108	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
JOHHMKPA_01238	8.06e-313	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JOHHMKPA_01239	4.67e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JOHHMKPA_01240	7.31e-181	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
JOHHMKPA_01241	1.42e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JOHHMKPA_01242	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JOHHMKPA_01243	1.23e-194	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
JOHHMKPA_01244	1.73e-169	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JOHHMKPA_01245	3.71e-199	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JOHHMKPA_01246	4.11e-124	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
JOHHMKPA_01247	7.2e-49	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
JOHHMKPA_01248	3.67e-88	-	-	-	P	-	-	-	NhaP-type Na H and K H
JOHHMKPA_01249	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
JOHHMKPA_01250	8.63e-191	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
JOHHMKPA_01251	1.8e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
JOHHMKPA_01252	5.13e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JOHHMKPA_01253	8.13e-206	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOHHMKPA_01254	2.75e-111	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
JOHHMKPA_01255	1.11e-41	yagE	-	-	E	-	-	-	Amino acid permease
JOHHMKPA_01256	2.25e-125	yagE	-	-	E	-	-	-	Amino acid permease
JOHHMKPA_01257	2.81e-189	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
JOHHMKPA_01258	4.87e-187	-	-	-	F	-	-	-	Phosphorylase superfamily
JOHHMKPA_01259	6.97e-53	-	-	-	F	-	-	-	NUDIX domain
JOHHMKPA_01260	2.14e-104	-	-	-	S	-	-	-	AAA domain
JOHHMKPA_01261	2.87e-107	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
JOHHMKPA_01262	3.2e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
JOHHMKPA_01263	2.48e-313	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
JOHHMKPA_01264	6.53e-291	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
JOHHMKPA_01265	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
JOHHMKPA_01266	1.76e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
JOHHMKPA_01267	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
JOHHMKPA_01268	1.8e-34	-	-	-	-	-	-	-	-
JOHHMKPA_01269	2.24e-202	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
JOHHMKPA_01270	8.21e-215	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
JOHHMKPA_01271	7.84e-89	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JOHHMKPA_01272	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JOHHMKPA_01273	2.9e-254	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JOHHMKPA_01274	3.72e-202	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
JOHHMKPA_01275	4.57e-163	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_01276	1.68e-149	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
JOHHMKPA_01277	1.48e-138	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
JOHHMKPA_01279	3.71e-76	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
JOHHMKPA_01280	1.37e-173	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOHHMKPA_01281	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
JOHHMKPA_01282	4.97e-311	ynbB	-	-	P	-	-	-	aluminum resistance
JOHHMKPA_01283	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
JOHHMKPA_01284	0.0	-	-	-	E	-	-	-	Amino acid permease
JOHHMKPA_01285	7.88e-121	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
JOHHMKPA_01286	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
JOHHMKPA_01287	3.03e-145	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
JOHHMKPA_01288	1.31e-16	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
JOHHMKPA_01289	2.95e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JOHHMKPA_01290	9.93e-72	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JOHHMKPA_01291	5.49e-197	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
JOHHMKPA_01292	5.61e-124	-	-	-	M	-	-	-	LysM domain protein
JOHHMKPA_01293	3.3e-16	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
JOHHMKPA_01294	3.43e-11	-	-	-	T	ko:K07172	-	ko00000,ko02048	SpoVT / AbrB like domain
JOHHMKPA_01295	2.51e-219	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
JOHHMKPA_01296	2.16e-39	-	-	-	-	-	-	-	-
JOHHMKPA_01297	1.04e-23	-	-	-	-	-	-	-	-
JOHHMKPA_01300	2.12e-27	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
JOHHMKPA_01301	7.67e-57	-	-	-	-	-	-	-	-
JOHHMKPA_01305	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
JOHHMKPA_01306	6.64e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JOHHMKPA_01307	4.68e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
JOHHMKPA_01308	1.14e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JOHHMKPA_01309	3.3e-197	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JOHHMKPA_01310	1.14e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JOHHMKPA_01311	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JOHHMKPA_01312	8.7e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JOHHMKPA_01313	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JOHHMKPA_01314	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
JOHHMKPA_01315	1.56e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JOHHMKPA_01316	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JOHHMKPA_01317	3.03e-44	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JOHHMKPA_01318	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JOHHMKPA_01319	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JOHHMKPA_01320	7.94e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JOHHMKPA_01321	7.18e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JOHHMKPA_01322	4.84e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JOHHMKPA_01323	3.73e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JOHHMKPA_01324	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
JOHHMKPA_01325	4.95e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
JOHHMKPA_01326	1.2e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JOHHMKPA_01327	1.51e-154	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JOHHMKPA_01328	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JOHHMKPA_01329	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
JOHHMKPA_01330	2.07e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JOHHMKPA_01331	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JOHHMKPA_01332	3.62e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOHHMKPA_01333	2.23e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
JOHHMKPA_01334	5.91e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOHHMKPA_01335	1.58e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOHHMKPA_01336	1.53e-175	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOHHMKPA_01337	5.08e-193	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JOHHMKPA_01338	5.35e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JOHHMKPA_01339	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
JOHHMKPA_01340	1.93e-138	-	-	-	L	-	-	-	Phage integrase family
JOHHMKPA_01341	2.94e-40	-	-	-	L	-	-	-	Phage integrase family
JOHHMKPA_01342	5.18e-90	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
JOHHMKPA_01343	1.86e-114	ymdB	-	-	S	-	-	-	Macro domain protein
JOHHMKPA_01345	3.32e-284	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
JOHHMKPA_01349	4.73e-84	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
JOHHMKPA_01350	1.39e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
JOHHMKPA_01351	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
JOHHMKPA_01352	2.73e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
JOHHMKPA_01353	2.85e-266	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
JOHHMKPA_01354	7.7e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
JOHHMKPA_01355	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
JOHHMKPA_01356	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
JOHHMKPA_01357	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
JOHHMKPA_01358	4.13e-99	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
JOHHMKPA_01359	1e-238	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JOHHMKPA_01360	2.18e-103	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
JOHHMKPA_01361	5.03e-297	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
JOHHMKPA_01362	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
JOHHMKPA_01363	2.55e-223	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
JOHHMKPA_01364	1.39e-120	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
JOHHMKPA_01365	4.92e-73	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
JOHHMKPA_01366	1.22e-157	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
JOHHMKPA_01367	2.28e-21	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
JOHHMKPA_01368	1.18e-89	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
JOHHMKPA_01369	4.07e-140	-	-	-	K	-	-	-	LysR family
JOHHMKPA_01370	0.0	-	-	-	C	-	-	-	FMN_bind
JOHHMKPA_01371	2.52e-140	-	-	-	K	-	-	-	LysR family
JOHHMKPA_01372	3.53e-287	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
JOHHMKPA_01373	0.0	-	-	-	C	-	-	-	FMN_bind
JOHHMKPA_01374	1.32e-57	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
JOHHMKPA_01375	2.43e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JOHHMKPA_01376	3.23e-108	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
JOHHMKPA_01377	2.95e-283	-	-	-	S	-	-	-	SLAP domain
JOHHMKPA_01378	4.28e-125	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
JOHHMKPA_01379	2.19e-18	-	-	-	-	-	-	-	-
JOHHMKPA_01380	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
JOHHMKPA_01381	3.52e-163	csrR	-	-	K	-	-	-	response regulator
JOHHMKPA_01382	2.19e-125	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
JOHHMKPA_01383	8.01e-276	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
JOHHMKPA_01384	5.95e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JOHHMKPA_01385	9.22e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
JOHHMKPA_01386	1.77e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JOHHMKPA_01387	5.03e-256	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
JOHHMKPA_01388	6.85e-109	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
JOHHMKPA_01389	3.01e-255	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
JOHHMKPA_01390	1.25e-192	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JOHHMKPA_01391	8.69e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JOHHMKPA_01392	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
JOHHMKPA_01393	1.07e-93	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JOHHMKPA_01394	6.18e-123	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
JOHHMKPA_01395	1.1e-128	-	-	-	E	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
JOHHMKPA_01396	2.32e-47	-	-	-	-	-	-	-	-
JOHHMKPA_01397	1.76e-233	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JOHHMKPA_01398	8.37e-161	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
JOHHMKPA_01399	1.11e-177	-	-	-	-	-	-	-	-
JOHHMKPA_01400	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
JOHHMKPA_01401	5.85e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_01402	7.36e-291	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
JOHHMKPA_01403	2.43e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
JOHHMKPA_01404	8.18e-163	-	-	-	-	-	-	-	-
JOHHMKPA_01405	1.69e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
JOHHMKPA_01406	7.8e-167	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
JOHHMKPA_01407	1.63e-200	-	-	-	I	-	-	-	alpha/beta hydrolase fold
JOHHMKPA_01408	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
JOHHMKPA_01409	8.82e-277	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JOHHMKPA_01410	1.62e-105	yveB	-	-	I	-	-	-	PAP2 superfamily
JOHHMKPA_01411	1.24e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
JOHHMKPA_01412	1.25e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
JOHHMKPA_01413	1.14e-164	terC	-	-	P	-	-	-	Integral membrane protein TerC family
JOHHMKPA_01414	7.63e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
JOHHMKPA_01415	4.04e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
JOHHMKPA_01416	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
JOHHMKPA_01417	2.89e-173	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_01418	1.4e-191	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
JOHHMKPA_01419	2.42e-204	-	-	-	L	-	-	-	HNH nucleases
JOHHMKPA_01420	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
JOHHMKPA_01421	3.67e-225	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
JOHHMKPA_01422	4.75e-239	-	-	-	M	-	-	-	Glycosyl transferase
JOHHMKPA_01423	1.34e-09	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
JOHHMKPA_01424	9.69e-25	-	-	-	-	-	-	-	-
JOHHMKPA_01425	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
JOHHMKPA_01426	3.34e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
JOHHMKPA_01427	7.23e-244	ysdE	-	-	P	-	-	-	Citrate transporter
JOHHMKPA_01428	1.43e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
JOHHMKPA_01429	9.49e-207	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
JOHHMKPA_01430	1.05e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
JOHHMKPA_01431	2.7e-277	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
JOHHMKPA_01432	5.75e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOHHMKPA_01433	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
JOHHMKPA_01434	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
JOHHMKPA_01435	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JOHHMKPA_01436	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
JOHHMKPA_01437	4.47e-58	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
JOHHMKPA_01438	1.13e-308	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
JOHHMKPA_01439	7.06e-111	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
JOHHMKPA_01440	2.07e-203	-	-	-	K	-	-	-	Transcriptional regulator
JOHHMKPA_01441	1.31e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
JOHHMKPA_01442	3.51e-222	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
JOHHMKPA_01443	9.65e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
JOHHMKPA_01444	2.72e-236	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
JOHHMKPA_01446	8.68e-171	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
JOHHMKPA_01447	2.08e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JOHHMKPA_01448	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
JOHHMKPA_01449	1.34e-289	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JOHHMKPA_01450	5.56e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JOHHMKPA_01451	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
JOHHMKPA_01452	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
JOHHMKPA_01453	5.41e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_01454	2.1e-31	-	-	-	-	-	-	-	-
JOHHMKPA_01455	1.69e-06	-	-	-	-	-	-	-	-
JOHHMKPA_01456	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
JOHHMKPA_01457	4.69e-226	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JOHHMKPA_01458	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
JOHHMKPA_01459	2.8e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JOHHMKPA_01460	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
JOHHMKPA_01461	3.56e-47	-	-	-	-	-	-	-	-
JOHHMKPA_01462	4.13e-83	-	-	-	-	-	-	-	-
JOHHMKPA_01465	1.51e-159	-	-	-	-	-	-	-	-
JOHHMKPA_01466	4.83e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
JOHHMKPA_01467	1.24e-08	-	-	-	-	-	-	-	-
JOHHMKPA_01468	1.73e-48	-	-	-	-	-	-	-	-
JOHHMKPA_01469	0.0	snf	-	-	KL	-	-	-	domain protein
JOHHMKPA_01470	9.39e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JOHHMKPA_01471	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JOHHMKPA_01472	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JOHHMKPA_01473	1.11e-234	-	-	-	K	-	-	-	Transcriptional regulator
JOHHMKPA_01474	1.05e-221	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
JOHHMKPA_01475	1.17e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JOHHMKPA_01476	5.03e-76	-	-	-	K	-	-	-	Helix-turn-helix domain
JOHHMKPA_01477	1.87e-308	-	-	-	S	-	-	-	response to antibiotic
JOHHMKPA_01478	1.34e-162	-	-	-	-	-	-	-	-
JOHHMKPA_01479	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
JOHHMKPA_01480	6.28e-87	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
JOHHMKPA_01481	1.42e-57	-	-	-	-	-	-	-	-
JOHHMKPA_01482	4.65e-14	-	-	-	-	-	-	-	-
JOHHMKPA_01483	7.81e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
JOHHMKPA_01484	8.28e-176	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
JOHHMKPA_01485	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
JOHHMKPA_01486	8.75e-197	-	-	-	-	-	-	-	-
JOHHMKPA_01487	3.32e-13	-	-	-	-	-	-	-	-
JOHHMKPA_01488	5.45e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
JOHHMKPA_01489	5.6e-135	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
JOHHMKPA_01492	4.92e-20	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
JOHHMKPA_01493	1.23e-58	-	-	-	S	-	-	-	polysaccharide biosynthetic process
JOHHMKPA_01494	6.06e-41	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
JOHHMKPA_01495	6.79e-190	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
JOHHMKPA_01496	8.74e-62	-	-	-	-	-	-	-	-
JOHHMKPA_01497	2.88e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
JOHHMKPA_01498	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
JOHHMKPA_01499	1.02e-29	-	-	-	S	-	-	-	Alpha beta hydrolase
JOHHMKPA_01500	2.48e-80	-	-	-	S	-	-	-	Alpha beta hydrolase
JOHHMKPA_01501	8.51e-50	-	-	-	-	-	-	-	-
JOHHMKPA_01502	4.3e-66	-	-	-	-	-	-	-	-
JOHHMKPA_01503	9.38e-189	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
JOHHMKPA_01504	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
JOHHMKPA_01505	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
JOHHMKPA_01506	1.82e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
JOHHMKPA_01507	1.23e-227	lipA	-	-	I	-	-	-	Carboxylesterase family
JOHHMKPA_01509	2.73e-268	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
JOHHMKPA_01510	8.57e-202	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
JOHHMKPA_01511	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
JOHHMKPA_01512	2.07e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
JOHHMKPA_01513	6.91e-92	-	-	-	L	-	-	-	IS1381, transposase OrfA
JOHHMKPA_01514	4.87e-96	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
JOHHMKPA_01515	1.17e-38	-	-	-	-	-	-	-	-
JOHHMKPA_01516	4.65e-184	-	-	-	D	-	-	-	AAA domain
JOHHMKPA_01517	5.88e-212	repA	-	-	S	-	-	-	Replication initiator protein A
JOHHMKPA_01518	1.14e-164	-	-	-	S	-	-	-	Fic/DOC family
JOHHMKPA_01519	1.79e-74	-	-	-	L	-	-	-	Resolvase, N-terminal
JOHHMKPA_01520	4.18e-208	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
JOHHMKPA_01521	1.86e-243	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
JOHHMKPA_01525	4.26e-22	-	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
JOHHMKPA_01526	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOHHMKPA_01527	2.13e-96	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
JOHHMKPA_01528	1.48e-249	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOHHMKPA_01529	1.66e-102	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
JOHHMKPA_01531	4.81e-77	-	-	-	S	-	-	-	SIR2-like domain
JOHHMKPA_01532	2.08e-118	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
JOHHMKPA_01533	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
JOHHMKPA_01534	5.22e-54	-	-	-	S	-	-	-	RloB-like protein
JOHHMKPA_01535	1.35e-208	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
JOHHMKPA_01536	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
JOHHMKPA_01537	0.0	-	-	-	S	-	-	-	SLAP domain
JOHHMKPA_01539	5.93e-302	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
JOHHMKPA_01540	1.43e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
JOHHMKPA_01541	1.65e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
JOHHMKPA_01543	4.05e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
JOHHMKPA_01544	5.55e-137	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
JOHHMKPA_01545	4.05e-209	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
JOHHMKPA_01546	2.84e-240	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
JOHHMKPA_01547	2.51e-184	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
JOHHMKPA_01548	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
JOHHMKPA_01549	1.48e-210	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
JOHHMKPA_01550	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
JOHHMKPA_01551	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
JOHHMKPA_01552	4.16e-280	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JOHHMKPA_01553	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
JOHHMKPA_01554	3.94e-252	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
JOHHMKPA_01555	3.31e-204	-	-	-	S	-	-	-	EDD domain protein, DegV family
JOHHMKPA_01556	2.06e-88	-	-	-	-	-	-	-	-
JOHHMKPA_01557	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
JOHHMKPA_01558	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
JOHHMKPA_01559	4.13e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
JOHHMKPA_01560	3.24e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
JOHHMKPA_01561	3.16e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JOHHMKPA_01562	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
JOHHMKPA_01563	1.61e-70	-	-	-	-	-	-	-	-
JOHHMKPA_01565	8.81e-40	-	-	-	M	-	-	-	Mycoplasma protein of unknown function, DUF285
JOHHMKPA_01566	9.86e-146	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
JOHHMKPA_01567	3.39e-88	-	-	-	S	ko:K06915	-	ko00000	cog cog0433
JOHHMKPA_01568	4.84e-109	-	-	-	L	-	-	-	Transposase and inactivated derivatives
JOHHMKPA_01570	3.31e-65	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
JOHHMKPA_01572	3.64e-309	-	-	-	M	-	-	-	Rib/alpha-like repeat
JOHHMKPA_01573	7.68e-129	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
JOHHMKPA_01575	4e-79	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
JOHHMKPA_01576	6.03e-215	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
JOHHMKPA_01577	5.22e-18	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
JOHHMKPA_01578	5.45e-72	-	-	-	-	-	-	-	-
JOHHMKPA_01580	5.2e-119	-	-	-	D	-	-	-	ftsk spoiiie
JOHHMKPA_01582	2.13e-53	-	-	-	-	-	-	-	-
JOHHMKPA_01583	3.06e-307	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
JOHHMKPA_01584	4.67e-75	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
JOHHMKPA_01585	2.82e-312	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
JOHHMKPA_01586	5.26e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
JOHHMKPA_01587	1.64e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
JOHHMKPA_01588	5.62e-187	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
JOHHMKPA_01589	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
JOHHMKPA_01590	2.12e-310	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
JOHHMKPA_01591	1.4e-207	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
JOHHMKPA_01592	1.89e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
JOHHMKPA_01593	1.53e-127	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
JOHHMKPA_01594	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
JOHHMKPA_01596	1.86e-31	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
JOHHMKPA_01597	1.2e-220	-	-	-	-	-	-	-	-
JOHHMKPA_01598	1.8e-139	-	-	-	L	-	-	-	PFAM Integrase catalytic
JOHHMKPA_01599	2.28e-76	eriC	-	-	P	ko:K03281	-	ko00000	chloride
JOHHMKPA_01600	1.59e-66	eriC	-	-	P	ko:K03281	-	ko00000	chloride
JOHHMKPA_01601	2.94e-74	eriC	-	-	P	ko:K03281	-	ko00000	chloride
JOHHMKPA_01602	1.45e-34	-	-	-	K	-	-	-	FCD
JOHHMKPA_01603	3.87e-20	-	-	-	K	-	-	-	FCD
JOHHMKPA_01604	4.37e-132	-	-	-	GM	-	-	-	NmrA-like family
JOHHMKPA_01605	5.5e-154	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JOHHMKPA_01606	1.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JOHHMKPA_01607	6.2e-212	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JOHHMKPA_01608	1.01e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JOHHMKPA_01609	9.05e-231	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
JOHHMKPA_01610	2.04e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JOHHMKPA_01611	4.22e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
JOHHMKPA_01612	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
JOHHMKPA_01613	6.69e-115	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
JOHHMKPA_01614	1.12e-104	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOHHMKPA_01615	1.12e-149	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
JOHHMKPA_01616	1.59e-259	pbpX1	-	-	V	-	-	-	Beta-lactamase
JOHHMKPA_01617	3.1e-127	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
JOHHMKPA_01618	7.89e-124	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
JOHHMKPA_01619	1.87e-290	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
JOHHMKPA_01620	5.74e-108	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
JOHHMKPA_01621	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
JOHHMKPA_01622	6.84e-243	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
JOHHMKPA_01623	1.12e-85	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JOHHMKPA_01624	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
JOHHMKPA_01625	4.21e-129	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
JOHHMKPA_01626	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
JOHHMKPA_01627	8.64e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JOHHMKPA_01628	3.17e-224	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
JOHHMKPA_01629	1.19e-188	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
JOHHMKPA_01630	7.44e-192	yycI	-	-	S	-	-	-	YycH protein
JOHHMKPA_01631	0.0	yycH	-	-	S	-	-	-	YycH protein
JOHHMKPA_01632	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
JOHHMKPA_01633	3.98e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
JOHHMKPA_01635	1.09e-46	-	-	-	-	-	-	-	-
JOHHMKPA_01637	4.19e-192	-	-	-	I	-	-	-	Acyl-transferase
JOHHMKPA_01638	7.23e-201	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
JOHHMKPA_01639	1.91e-236	-	-	-	M	-	-	-	Glycosyl transferase family 8
JOHHMKPA_01640	5.48e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
JOHHMKPA_01641	1.87e-213	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
JOHHMKPA_01642	1.61e-48	-	-	-	S	-	-	-	Cytochrome B5
JOHHMKPA_01644	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
JOHHMKPA_01645	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOHHMKPA_01646	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOHHMKPA_01647	7.71e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
JOHHMKPA_01648	1.47e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JOHHMKPA_01649	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JOHHMKPA_01650	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JOHHMKPA_01651	3.94e-183	-	-	-	P	-	-	-	Voltage gated chloride channel
JOHHMKPA_01652	2.83e-237	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
JOHHMKPA_01653	1.05e-69	-	-	-	-	-	-	-	-
JOHHMKPA_01654	1.17e-56	-	-	-	-	-	-	-	-
JOHHMKPA_01655	1.33e-295	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JOHHMKPA_01656	0.0	-	-	-	E	-	-	-	amino acid
JOHHMKPA_01657	1.64e-200	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
JOHHMKPA_01658	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
JOHHMKPA_01659	1.07e-52	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
JOHHMKPA_01660	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JOHHMKPA_01661	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JOHHMKPA_01662	9.39e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JOHHMKPA_01663	1.62e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JOHHMKPA_01664	1.33e-130	-	-	-	M	-	-	-	LysM domain protein
JOHHMKPA_01665	2.57e-108	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOHHMKPA_01666	6.31e-99	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOHHMKPA_01667	1.83e-22	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOHHMKPA_01668	1.25e-17	-	-	-	-	-	-	-	-
JOHHMKPA_01669	2.77e-220	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
JOHHMKPA_01670	1.04e-41	-	-	-	-	-	-	-	-
JOHHMKPA_01672	3.65e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
JOHHMKPA_01673	1.08e-145	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
JOHHMKPA_01674	4.51e-77	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
JOHHMKPA_01676	5.4e-174	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
JOHHMKPA_01677	1.49e-290	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
JOHHMKPA_01678	7.82e-80	-	-	-	-	-	-	-	-
JOHHMKPA_01679	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
JOHHMKPA_01680	2.14e-312	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
JOHHMKPA_01681	5.53e-173	-	-	-	S	-	-	-	TerB-C domain
JOHHMKPA_01682	3.99e-127	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
JOHHMKPA_01683	4.52e-35	dltr	-	-	K	-	-	-	response regulator
JOHHMKPA_01684	2.14e-85	dltr	-	-	K	-	-	-	response regulator
JOHHMKPA_01685	3e-290	sptS	-	-	T	-	-	-	Histidine kinase
JOHHMKPA_01686	5.3e-264	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
JOHHMKPA_01687	2.65e-89	-	-	-	O	-	-	-	OsmC-like protein
JOHHMKPA_01688	1.92e-113	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
JOHHMKPA_01689	2.05e-110	-	-	-	-	-	-	-	-
JOHHMKPA_01690	0.0	-	-	-	-	-	-	-	-
JOHHMKPA_01692	9.84e-63	-	-	-	S	-	-	-	Fic/DOC family
JOHHMKPA_01693	0.0	potE	-	-	E	-	-	-	Amino Acid
JOHHMKPA_01694	4.71e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JOHHMKPA_01695	4.78e-308	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
JOHHMKPA_01696	5.17e-169	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
JOHHMKPA_01697	2.15e-299	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
JOHHMKPA_01698	1.45e-36	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
JOHHMKPA_01699	1.73e-79	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
JOHHMKPA_01700	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
JOHHMKPA_01701	1.13e-201	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
JOHHMKPA_01702	2.91e-83	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
JOHHMKPA_01703	8.64e-85	yybA	-	-	K	-	-	-	Transcriptional regulator
JOHHMKPA_01704	8e-108	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
JOHHMKPA_01705	5.59e-109	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
JOHHMKPA_01706	2.88e-98	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
JOHHMKPA_01707	2.37e-242	-	-	-	T	-	-	-	GHKL domain
JOHHMKPA_01708	1.75e-168	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
JOHHMKPA_01709	1.28e-228	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
JOHHMKPA_01710	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
JOHHMKPA_01711	1.58e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
JOHHMKPA_01712	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JOHHMKPA_01713	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
JOHHMKPA_01714	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
JOHHMKPA_01715	5.35e-224	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JOHHMKPA_01716	3.68e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
JOHHMKPA_01717	1.72e-286	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
JOHHMKPA_01745	2.43e-239	-	-	-	S	-	-	-	Bacteriocin helveticin-J
JOHHMKPA_01746	1.33e-67	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
JOHHMKPA_01747	2.53e-139	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
JOHHMKPA_01748	1.98e-35	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
JOHHMKPA_01749	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JOHHMKPA_01750	7.81e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JOHHMKPA_01751	2.16e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JOHHMKPA_01752	1.29e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JOHHMKPA_01753	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
JOHHMKPA_01754	1.31e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
JOHHMKPA_01755	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JOHHMKPA_01756	5.59e-98	-	-	-	-	-	-	-	-
JOHHMKPA_01757	1.19e-29	-	-	-	-	-	-	-	-
JOHHMKPA_01758	7.91e-102	-	-	-	-	-	-	-	-
JOHHMKPA_01759	9.18e-202	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
JOHHMKPA_01760	2.94e-250	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
JOHHMKPA_01761	2.61e-23	-	-	-	-	-	-	-	-
JOHHMKPA_01762	1.05e-119	-	-	-	S	-	-	-	membrane
JOHHMKPA_01763	5.3e-92	-	-	-	K	-	-	-	LytTr DNA-binding domain
JOHHMKPA_01764	6.93e-34	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
JOHHMKPA_01765	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
JOHHMKPA_01766	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
JOHHMKPA_01767	2.2e-79	lysM	-	-	M	-	-	-	LysM domain
JOHHMKPA_01768	7.62e-223	-	-	-	-	-	-	-	-
JOHHMKPA_01769	6.74e-212	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
JOHHMKPA_01770	1.27e-58	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
JOHHMKPA_01771	1.76e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
JOHHMKPA_01772	6.9e-150	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
JOHHMKPA_01773	2.15e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
JOHHMKPA_01774	6.38e-184	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JOHHMKPA_01775	4.25e-119	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
JOHHMKPA_01776	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
JOHHMKPA_01777	9.89e-74	-	-	-	-	-	-	-	-
JOHHMKPA_01778	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
JOHHMKPA_01779	1.23e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
JOHHMKPA_01780	1.6e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
JOHHMKPA_01781	3.09e-71	-	-	-	-	-	-	-	-
JOHHMKPA_01782	2.96e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JOHHMKPA_01783	4.28e-187	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
JOHHMKPA_01784	1.29e-27	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
JOHHMKPA_01785	3.75e-168	-	-	-	K	-	-	-	rpiR family
JOHHMKPA_01786	7.66e-248	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
JOHHMKPA_01787	1.81e-270	-	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
JOHHMKPA_01788	1.32e-151	-	-	-	S	-	-	-	Putative esterase
JOHHMKPA_01789	3.39e-154	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JOHHMKPA_01790	1.92e-102	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
JOHHMKPA_01792	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
JOHHMKPA_01793	7.29e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JOHHMKPA_01796	5.31e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
JOHHMKPA_01799	7.53e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
JOHHMKPA_01800	1.51e-150	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
JOHHMKPA_01801	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
JOHHMKPA_01802	3e-139	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
JOHHMKPA_01803	9.78e-136	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
JOHHMKPA_01804	7.09e-184	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
JOHHMKPA_01805	1.36e-96	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
JOHHMKPA_01806	1.88e-125	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
JOHHMKPA_01807	1.95e-218	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
JOHHMKPA_01808	1.48e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JOHHMKPA_01809	1.24e-75	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
JOHHMKPA_01810	3.99e-56	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
JOHHMKPA_01811	1.6e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
JOHHMKPA_01812	1.56e-198	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
JOHHMKPA_01813	1.63e-159	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
JOHHMKPA_01814	1.03e-47	-	-	-	-	-	-	-	-
JOHHMKPA_01815	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
JOHHMKPA_01816	6.38e-154	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
JOHHMKPA_01817	3.86e-109	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
JOHHMKPA_01818	3.73e-76	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
JOHHMKPA_01819	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
JOHHMKPA_01820	4.14e-113	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
JOHHMKPA_01827	1.28e-54	-	-	-	-	-	-	-	-
JOHHMKPA_01828	2.12e-27	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
JOHHMKPA_01831	6.31e-27	-	-	-	-	-	-	-	-
JOHHMKPA_01832	1.76e-38	-	-	-	-	-	-	-	-
JOHHMKPA_01833	1.54e-112	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
JOHHMKPA_01834	4.51e-60	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
JOHHMKPA_01835	5.3e-32	-	-	-	-	-	-	-	-
JOHHMKPA_01836	9.71e-47	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
JOHHMKPA_01837	7e-131	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
JOHHMKPA_01838	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
JOHHMKPA_01839	1.15e-121	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JOHHMKPA_01840	4.97e-64	-	-	-	S	-	-	-	Metal binding domain of Ada
JOHHMKPA_01841	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
JOHHMKPA_01842	3.03e-177	lysR5	-	-	K	-	-	-	LysR substrate binding domain
JOHHMKPA_01843	2.06e-298	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
JOHHMKPA_01844	5.39e-84	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JOHHMKPA_01845	2.01e-135	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
JOHHMKPA_01846	1.76e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
JOHHMKPA_01847	1.07e-287	-	-	-	S	-	-	-	Sterol carrier protein domain
JOHHMKPA_01848	4.04e-29	-	-	-	-	-	-	-	-
JOHHMKPA_01849	6.93e-140	-	-	-	K	-	-	-	LysR substrate binding domain
JOHHMKPA_01850	1.13e-126	-	-	-	-	-	-	-	-
JOHHMKPA_01851	5.04e-154	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
JOHHMKPA_01852	7.74e-61	-	-	-	-	-	-	-	-
JOHHMKPA_01853	1.84e-44	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
JOHHMKPA_01854	1.94e-150	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
JOHHMKPA_01855	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JOHHMKPA_01856	2.79e-185	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
JOHHMKPA_01857	1.74e-111	-	-	-	-	-	-	-	-
JOHHMKPA_01858	7.76e-98	-	-	-	-	-	-	-	-
JOHHMKPA_01859	1.76e-181	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
JOHHMKPA_01860	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JOHHMKPA_01861	5.93e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
JOHHMKPA_01862	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
JOHHMKPA_01863	7.23e-50	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
JOHHMKPA_01864	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
JOHHMKPA_01865	2.27e-179	-	-	-	-	-	-	-	-
JOHHMKPA_01869	2.23e-48	-	-	-	-	-	-	-	-
JOHHMKPA_01870	2.52e-76	-	-	-	S	-	-	-	Cupredoxin-like domain
JOHHMKPA_01871	4.44e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
JOHHMKPA_01872	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
JOHHMKPA_01873	6.63e-147	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
JOHHMKPA_01874	7.41e-136	-	-	-	-	-	-	-	-
JOHHMKPA_01875	1.03e-65	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
JOHHMKPA_01876	3.76e-18	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
JOHHMKPA_01877	7.51e-16	-	-	-	L	-	-	-	Transposase
JOHHMKPA_01878	1.01e-22	-	-	-	L	-	-	-	Transposase
JOHHMKPA_01879	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
JOHHMKPA_01880	5.85e-86	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
JOHHMKPA_01881	1.52e-157	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
JOHHMKPA_01882	1.78e-163	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
JOHHMKPA_01883	2.85e-115	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
JOHHMKPA_01884	4.82e-42	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
JOHHMKPA_01885	5.39e-292	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
JOHHMKPA_01886	4.93e-80	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
JOHHMKPA_01887	6.33e-221	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
JOHHMKPA_01888	4.19e-92	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
JOHHMKPA_01893	2.84e-108	-	-	-	K	-	-	-	FR47-like protein
JOHHMKPA_01894	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
JOHHMKPA_01895	2.77e-248	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOHHMKPA_01896	3.91e-214	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JOHHMKPA_01897	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JOHHMKPA_01898	2.75e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JOHHMKPA_01899	1.61e-81	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
JOHHMKPA_01900	7.52e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
JOHHMKPA_01901	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
JOHHMKPA_01902	7.03e-307	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JOHHMKPA_01904	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
JOHHMKPA_01905	1.77e-157	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
JOHHMKPA_01906	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
JOHHMKPA_01907	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
JOHHMKPA_01908	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
JOHHMKPA_01909	2.65e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JOHHMKPA_01910	3.37e-192	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JOHHMKPA_01911	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JOHHMKPA_01912	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JOHHMKPA_01913	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
JOHHMKPA_01914	5.38e-39	-	-	-	-	-	-	-	-
JOHHMKPA_01915	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JOHHMKPA_01916	9.41e-285	-	-	-	V	-	-	-	ABC transporter transmembrane region
JOHHMKPA_01917	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOHHMKPA_01918	3.52e-293	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
JOHHMKPA_01919	1.17e-56	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JOHHMKPA_01920	1.34e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
JOHHMKPA_01921	1.4e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
JOHHMKPA_01922	1.96e-148	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
JOHHMKPA_01923	1.13e-41	-	-	-	M	-	-	-	Lysin motif
JOHHMKPA_01924	8.49e-146	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JOHHMKPA_01925	8.44e-300	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
JOHHMKPA_01926	4.36e-93	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
JOHHMKPA_01927	2.43e-95	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
JOHHMKPA_01928	2.33e-130	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
JOHHMKPA_01929	3.87e-15	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
JOHHMKPA_01930	1.63e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
JOHHMKPA_01931	1.73e-227	-	-	-	S	-	-	-	Conserved hypothetical protein 698
JOHHMKPA_01933	1.21e-243	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
JOHHMKPA_01934	2.71e-222	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
JOHHMKPA_01935	6.46e-27	-	-	-	-	-	-	-	-
JOHHMKPA_01936	6.49e-268	-	-	-	-	-	-	-	-
JOHHMKPA_01937	6.57e-175	-	-	-	S	-	-	-	SLAP domain
JOHHMKPA_01938	1.14e-154	-	-	-	S	-	-	-	SLAP domain
JOHHMKPA_01939	1.06e-133	-	-	-	S	-	-	-	Bacteriocin helveticin-J
JOHHMKPA_01940	2.35e-58	-	-	-	-	-	-	-	-
JOHHMKPA_01941	8.29e-76	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
JOHHMKPA_01942	1.98e-41	-	-	-	E	-	-	-	Zn peptidase
JOHHMKPA_01943	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
JOHHMKPA_01944	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOHHMKPA_01945	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOHHMKPA_01946	4.22e-267	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JOHHMKPA_01947	1.13e-48	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
JOHHMKPA_01948	8.11e-245	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JOHHMKPA_01949	9.14e-317	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JOHHMKPA_01950	6.03e-218	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
JOHHMKPA_01951	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
JOHHMKPA_01952	5.6e-129	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
JOHHMKPA_01953	2.23e-197	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JOHHMKPA_01954	9.64e-307	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
JOHHMKPA_01956	1.59e-61	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
JOHHMKPA_01957	3.54e-300	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
JOHHMKPA_01958	6.76e-80	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
JOHHMKPA_01959	1.77e-194	-	-	-	I	-	-	-	alpha/beta hydrolase fold
JOHHMKPA_01960	3.2e-143	-	-	-	S	-	-	-	SNARE associated Golgi protein
JOHHMKPA_01961	1.23e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
JOHHMKPA_01962	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JOHHMKPA_01963	4.98e-37	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
JOHHMKPA_01964	1.44e-53	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
JOHHMKPA_01965	9.06e-184	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
JOHHMKPA_01966	1.38e-165	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
JOHHMKPA_01969	4.45e-42	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
JOHHMKPA_01970	1.74e-119	-	-	-	-	-	-	-	-
JOHHMKPA_01971	1.25e-248	-	-	-	K	-	-	-	IrrE N-terminal-like domain
JOHHMKPA_01974	4.63e-250	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
JOHHMKPA_01976	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
JOHHMKPA_01977	2.76e-83	-	-	-	-	-	-	-	-
JOHHMKPA_01978	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
JOHHMKPA_01979	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
JOHHMKPA_01980	1.1e-110	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
JOHHMKPA_01981	1.23e-242	-	-	-	S	-	-	-	TerB-C domain
JOHHMKPA_01982	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
JOHHMKPA_01983	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
JOHHMKPA_01984	6.94e-202	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
JOHHMKPA_01985	9.05e-78	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
JOHHMKPA_01986	3.36e-42	-	-	-	-	-	-	-	-
JOHHMKPA_01987	1.78e-100	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
JOHHMKPA_01988	5.26e-36	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
JOHHMKPA_01989	7.46e-113	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
JOHHMKPA_01990	5.14e-105	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
JOHHMKPA_01991	9.98e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
JOHHMKPA_01992	3.44e-209	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
JOHHMKPA_01993	3.22e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
JOHHMKPA_01994	2.12e-273	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
JOHHMKPA_01995	4.42e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
JOHHMKPA_01996	4.43e-179	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
JOHHMKPA_01997	6.22e-232	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
JOHHMKPA_01998	1.39e-224	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JOHHMKPA_01999	6.98e-78	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
JOHHMKPA_02000	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
JOHHMKPA_02001	1.64e-59	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
JOHHMKPA_02002	1.27e-311	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
JOHHMKPA_02003	1.18e-95	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
JOHHMKPA_02005	5.89e-316	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
JOHHMKPA_02006	1.22e-195	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
JOHHMKPA_02007	4.48e-174	potA11	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
JOHHMKPA_02008	7.05e-146	potC3	-	-	E	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
JOHHMKPA_02009	1.58e-10	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
JOHHMKPA_02010	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
JOHHMKPA_02011	2.46e-48	-	-	-	-	-	-	-	-
JOHHMKPA_02013	1.46e-161	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
JOHHMKPA_02014	4.6e-113	-	-	-	K	-	-	-	GNAT family
JOHHMKPA_02015	5.25e-258	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
JOHHMKPA_02016	4.45e-156	rbtT	-	-	P	ko:K13021	-	ko00000,ko02000	Major Facilitator Superfamily
JOHHMKPA_02017	2.81e-76	-	-	-	EGP	-	-	-	Major Facilitator
JOHHMKPA_02018	1.08e-161	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
JOHHMKPA_02019	1.48e-139	-	-	-	EGP	-	-	-	Major Facilitator
JOHHMKPA_02020	9.16e-301	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
JOHHMKPA_02021	7.84e-95	-	-	-	EGP	-	-	-	Major Facilitator
JOHHMKPA_02022	2.58e-45	-	-	-	-	-	-	-	-
JOHHMKPA_02024	3.3e-42	-	-	-	-	-	-	-	-
JOHHMKPA_02025	1.62e-96	-	-	-	M	-	-	-	LysM domain
JOHHMKPA_02026	5.75e-152	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
JOHHMKPA_02027	5.29e-256	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JOHHMKPA_02028	2.25e-137	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
JOHHMKPA_02029	4.58e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
JOHHMKPA_02030	1.15e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
JOHHMKPA_02031	1.32e-114	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
JOHHMKPA_02032	1.16e-13	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
JOHHMKPA_02033	1.28e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
JOHHMKPA_02034	8.73e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
JOHHMKPA_02035	9.01e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
JOHHMKPA_02036	1.92e-80	yneE	-	-	K	-	-	-	Transcriptional regulator
JOHHMKPA_02037	2.18e-122	yneE	-	-	K	-	-	-	Transcriptional regulator
JOHHMKPA_02038	3.58e-61	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
JOHHMKPA_02039	5.05e-11	-	-	-	-	-	-	-	-
JOHHMKPA_02040	3.69e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
JOHHMKPA_02041	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JOHHMKPA_02042	1.24e-258	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
JOHHMKPA_02043	1.5e-90	-	-	-	-	-	-	-	-
JOHHMKPA_02044	4.36e-142	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
JOHHMKPA_02045	3.35e-269	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
JOHHMKPA_02046	5.29e-164	-	-	-	S	-	-	-	Alpha/beta hydrolase family
JOHHMKPA_02047	2.62e-199	epsV	-	-	S	-	-	-	glycosyl transferase family 2
JOHHMKPA_02048	9.18e-187	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
JOHHMKPA_02049	5.07e-190	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JOHHMKPA_02050	1.24e-232	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
JOHHMKPA_02051	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOHHMKPA_02052	2.29e-112	-	-	-	-	-	-	-	-
JOHHMKPA_02053	1.23e-166	-	-	-	S	-	-	-	(CBS) domain
JOHHMKPA_02054	2.93e-234	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
JOHHMKPA_02055	1.89e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JOHHMKPA_02056	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JOHHMKPA_02057	6.06e-54	yabO	-	-	J	-	-	-	S4 domain protein
JOHHMKPA_02058	4.78e-261	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
JOHHMKPA_02059	1.53e-122	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
JOHHMKPA_02060	6.49e-137	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
JOHHMKPA_02063	8.95e-70	-	-	-	K	-	-	-	LytTr DNA-binding domain
JOHHMKPA_02064	9.29e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
JOHHMKPA_02065	1.81e-190	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
JOHHMKPA_02066	2.25e-30	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
JOHHMKPA_02067	5.94e-148	-	-	-	I	-	-	-	Acid phosphatase homologues
JOHHMKPA_02068	2.25e-241	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
JOHHMKPA_02069	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
JOHHMKPA_02070	3.6e-106	-	-	-	C	-	-	-	Flavodoxin
JOHHMKPA_02071	1.61e-145	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
JOHHMKPA_02072	1.71e-154	-	-	-	L	ko:K07459	-	ko00000	AAA ATPase domain
JOHHMKPA_02074	6.54e-222	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
JOHHMKPA_02075	7.1e-252	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
JOHHMKPA_02076	7.82e-240	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOHHMKPA_02077	1.34e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOHHMKPA_02078	2.64e-266	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JOHHMKPA_02079	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_02080	1.19e-114	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
JOHHMKPA_02081	1.09e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
JOHHMKPA_02082	6.67e-115	-	-	-	G	-	-	-	Peptidase_C39 like family
JOHHMKPA_02083	2.16e-207	-	-	-	M	-	-	-	NlpC/P60 family
JOHHMKPA_02084	1.93e-32	-	-	-	G	-	-	-	Peptidase_C39 like family
JOHHMKPA_02086	1.39e-143	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
JOHHMKPA_02087	5.71e-230	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
JOHHMKPA_02088	7.13e-67	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
JOHHMKPA_02089	1.53e-189	-	5.2.1.13	-	Q	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
JOHHMKPA_02090	3.43e-79	-	-	-	C	-	-	-	2Fe-2S iron-sulfur cluster binding domain
JOHHMKPA_02091	6.73e-78	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
JOHHMKPA_02092	2.16e-79	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
JOHHMKPA_02093	5.96e-283	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
JOHHMKPA_02094	3.76e-316	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOHHMKPA_02096	1.62e-278	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JOHHMKPA_02097	2.75e-143	-	-	-	G	-	-	-	phosphoglycerate mutase
JOHHMKPA_02098	1.45e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
JOHHMKPA_02099	1.05e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
JOHHMKPA_02100	2.12e-132	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
JOHHMKPA_02101	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
JOHHMKPA_02102	5.51e-35	-	-	-	-	-	-	-	-
JOHHMKPA_02103	8.71e-31	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
JOHHMKPA_02104	6.13e-70	-	-	-	K	-	-	-	sequence-specific DNA binding
JOHHMKPA_02105	5.97e-55	-	-	-	S	-	-	-	SnoaL-like domain
JOHHMKPA_02106	0.0	-	-	-	L	-	-	-	PLD-like domain
JOHHMKPA_02107	2.52e-06	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
JOHHMKPA_02108	0.0	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
JOHHMKPA_02109	4.97e-45	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537,ko:K12952	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
JOHHMKPA_02111	8.41e-42	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
JOHHMKPA_02112	2.24e-71	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
JOHHMKPA_02113	1.82e-177	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
JOHHMKPA_02115	3.68e-176	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JOHHMKPA_02116	3.05e-110	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
JOHHMKPA_02117	6.13e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
JOHHMKPA_02118	5.94e-200	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
JOHHMKPA_02119	8.97e-47	-	-	-	-	-	-	-	-
JOHHMKPA_02120	1.96e-127	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
JOHHMKPA_02121	7.28e-209	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
JOHHMKPA_02122	4.83e-107	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
JOHHMKPA_02123	1.53e-142	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
JOHHMKPA_02124	6.21e-153	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
JOHHMKPA_02125	1.63e-313	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
JOHHMKPA_02127	0.0	-	-	-	L	-	-	-	AAA domain
JOHHMKPA_02128	6.84e-15	-	-	-	V	-	-	-	Abi-like protein
JOHHMKPA_02129	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
JOHHMKPA_02130	7.27e-42	-	-	-	-	-	-	-	-
JOHHMKPA_02131	1.47e-91	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Prophage maintenance system killer protein
JOHHMKPA_02134	4.61e-37	-	-	-	S	-	-	-	Enterocin A Immunity
JOHHMKPA_02136	3.55e-28	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
JOHHMKPA_02137	3.34e-303	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
JOHHMKPA_02138	4.14e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JOHHMKPA_02139	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
JOHHMKPA_02140	2.14e-103	-	-	-	-	-	-	-	-
JOHHMKPA_02141	4.95e-164	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
JOHHMKPA_02142	4.77e-248	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
JOHHMKPA_02143	1.28e-226	-	-	-	S	-	-	-	PFAM Archaeal ATPase
JOHHMKPA_02144	1.86e-91	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
JOHHMKPA_02145	1.7e-29	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
JOHHMKPA_02146	7.24e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
JOHHMKPA_02147	1.29e-230	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
JOHHMKPA_02148	5.11e-203	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JOHHMKPA_02149	2.23e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
JOHHMKPA_02150	2.94e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
JOHHMKPA_02151	1.94e-130	-	-	-	I	-	-	-	PAP2 superfamily
JOHHMKPA_02152	1.23e-187	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
JOHHMKPA_02153	1.43e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JOHHMKPA_02154	3.73e-72	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
JOHHMKPA_02155	1.93e-56	-	-	-	L	-	-	-	Transposase DDE domain
JOHHMKPA_02156	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
JOHHMKPA_02157	2.24e-29	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
JOHHMKPA_02158	4.53e-11	-	-	-	-	-	-	-	-
JOHHMKPA_02159	1.02e-75	-	-	-	-	-	-	-	-
JOHHMKPA_02160	2.62e-69	-	-	-	-	-	-	-	-
JOHHMKPA_02162	4.4e-165	-	-	-	S	-	-	-	PAS domain
JOHHMKPA_02166	9.07e-51	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
JOHHMKPA_02167	4.67e-54	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JOHHMKPA_02168	1.44e-164	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JOHHMKPA_02169	9e-104	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
JOHHMKPA_02170	1.5e-93	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
JOHHMKPA_02171	5.53e-147	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
JOHHMKPA_02172	4.31e-175	-	-	-	-	-	-	-	-
JOHHMKPA_02173	2.76e-112	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
JOHHMKPA_02174	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
JOHHMKPA_02175	2.35e-117	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
JOHHMKPA_02176	1.41e-37	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
JOHHMKPA_02177	1.19e-19	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
JOHHMKPA_02178	4.06e-109	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
JOHHMKPA_02179	4.17e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
JOHHMKPA_02180	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
JOHHMKPA_02181	1.64e-45	-	-	-	-	-	-	-	-
JOHHMKPA_02182	3.31e-154	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
JOHHMKPA_02183	3.82e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
JOHHMKPA_02184	1.04e-94	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
JOHHMKPA_02185	2.08e-164	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
JOHHMKPA_02186	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JOHHMKPA_02187	2.23e-99	-	-	-	S	-	-	-	helix_turn_helix, Deoxyribose operon repressor
JOHHMKPA_02188	6.72e-177	-	-	-	EP	-	-	-	Plasmid replication protein
JOHHMKPA_02189	4.63e-32	-	-	-	-	-	-	-	-
JOHHMKPA_02190	5.01e-55	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
JOHHMKPA_02192	4.39e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
JOHHMKPA_02193	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
JOHHMKPA_02194	2.14e-48	-	-	-	-	-	-	-	-
JOHHMKPA_02195	1.14e-208	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
JOHHMKPA_02196	5.69e-179	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
JOHHMKPA_02197	7.71e-133	-	-	-	L	-	-	-	Integrase
JOHHMKPA_02198	4.02e-91	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
JOHHMKPA_02199	5.32e-42	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
JOHHMKPA_02200	2.74e-06	-	-	-	S	-	-	-	PFAM Archaeal ATPase
JOHHMKPA_02201	5.46e-182	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
JOHHMKPA_02202	7.62e-134	-	-	-	G	-	-	-	Phosphoglycerate mutase family
JOHHMKPA_02203	5.73e-153	-	-	-	-	-	-	-	-
JOHHMKPA_02204	8.93e-108	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
JOHHMKPA_02205	3.55e-56	-	-	-	L	-	-	-	Helix-turn-helix domain
JOHHMKPA_02206	4.47e-148	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
JOHHMKPA_02207	1.15e-64	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
JOHHMKPA_02208	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
JOHHMKPA_02209	0.0	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
JOHHMKPA_02210	1.45e-183	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
JOHHMKPA_02211	9.79e-181	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
JOHHMKPA_02212	4.19e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
JOHHMKPA_02213	5.4e-161	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
JOHHMKPA_02214	8.08e-108	-	-	-	S	-	-	-	PFAM Archaeal ATPase
JOHHMKPA_02215	1.32e-105	-	-	-	S	-	-	-	PFAM Archaeal ATPase
JOHHMKPA_02216	7.02e-36	-	-	-	-	-	-	-	-
JOHHMKPA_02217	2.22e-296	-	-	-	E	ko:K03294	-	ko00000	amino acid
JOHHMKPA_02218	0.0	-	-	-	L	-	-	-	Transposase DDE domain
JOHHMKPA_02219	1.28e-168	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
JOHHMKPA_02220	6.59e-296	-	-	-	L	-	-	-	Transposase DDE domain
JOHHMKPA_02221	3.16e-179	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
JOHHMKPA_02222	7.8e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
JOHHMKPA_02223	8.79e-222	-	-	-	L	-	-	-	DDE superfamily endonuclease
JOHHMKPA_02224	2.57e-206	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
JOHHMKPA_02225	3.74e-125	-	-	-	-	-	-	-	-
JOHHMKPA_02226	1.34e-34	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
JOHHMKPA_02227	2.37e-169	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
JOHHMKPA_02228	5.57e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
JOHHMKPA_02229	4.52e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
JOHHMKPA_02231	2.99e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JOHHMKPA_02232	2.09e-105	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
JOHHMKPA_02233	1.01e-98	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
JOHHMKPA_02234	1.06e-195	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
JOHHMKPA_02235	7.52e-221	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
JOHHMKPA_02236	3.87e-16	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
JOHHMKPA_02237	2.08e-95	yfhC	-	-	C	-	-	-	nitroreductase
JOHHMKPA_02238	1.88e-157	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)