ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
GKNECEFK_00001 0.0 - - - - - - - -
GKNECEFK_00003 9.26e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
GKNECEFK_00004 2.86e-244 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GKNECEFK_00005 2.86e-286 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
GKNECEFK_00006 5.46e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GKNECEFK_00007 1.18e-253 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
GKNECEFK_00008 3.07e-124 - - - - - - - -
GKNECEFK_00009 2.81e-200 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
GKNECEFK_00010 1.64e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GKNECEFK_00011 1.1e-232 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
GKNECEFK_00012 4.82e-113 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
GKNECEFK_00013 1.51e-127 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GKNECEFK_00014 2.84e-208 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
GKNECEFK_00015 1.25e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GKNECEFK_00016 8.77e-173 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKNECEFK_00017 3.69e-170 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKNECEFK_00018 3.46e-266 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKNECEFK_00019 2.13e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKNECEFK_00020 2.76e-221 ybbR - - S - - - YbbR-like protein
GKNECEFK_00021 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKNECEFK_00022 8.04e-190 - - - S - - - hydrolase
GKNECEFK_00023 3.23e-98 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
GKNECEFK_00024 2.85e-153 - - - - - - - -
GKNECEFK_00025 3.07e-112 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKNECEFK_00026 2.52e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GKNECEFK_00027 8.39e-195 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
GKNECEFK_00028 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKNECEFK_00029 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKNECEFK_00030 5.12e-199 ybcH - - D ko:K06889 - ko00000 Alpha beta
GKNECEFK_00031 6.91e-118 - - - T - - - Putative diguanylate phosphodiesterase
GKNECEFK_00032 2.21e-34 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
GKNECEFK_00033 1.67e-136 icaA - - M - - - Glycosyl transferase family group 2
GKNECEFK_00034 2.64e-46 - - - - - - - -
GKNECEFK_00035 1.96e-110 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
GKNECEFK_00036 1.14e-99 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GKNECEFK_00038 0.0 - - - E - - - Amino acid permease
GKNECEFK_00039 2.15e-127 - - - L - - - Helix-turn-helix domain
GKNECEFK_00040 4.31e-204 - - - L ko:K07497 - ko00000 hmm pf00665
GKNECEFK_00042 3.96e-37 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKNECEFK_00043 1.49e-130 ylbE - - GM - - - NAD(P)H-binding
GKNECEFK_00044 2.33e-120 - - - S - - - VanZ like family
GKNECEFK_00045 5.65e-171 yebC - - K - - - Transcriptional regulatory protein
GKNECEFK_00046 5.04e-231 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
GKNECEFK_00047 2.01e-221 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
GKNECEFK_00048 7.88e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
GKNECEFK_00049 8.19e-91 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
GKNECEFK_00050 1.68e-55 - - - - - - - -
GKNECEFK_00051 1.94e-100 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
GKNECEFK_00052 3.69e-30 - - - - - - - -
GKNECEFK_00053 1.03e-239 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
GKNECEFK_00054 1.07e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKNECEFK_00056 3e-128 - - - M - - - Protein of unknown function (DUF3737)
GKNECEFK_00057 1.72e-288 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
GKNECEFK_00058 1.93e-242 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GKNECEFK_00059 9.01e-90 - - - S - - - SdpI/YhfL protein family
GKNECEFK_00060 4.96e-167 - - - K - - - Transcriptional regulatory protein, C terminal
GKNECEFK_00061 0.0 yclK - - T - - - Histidine kinase
GKNECEFK_00062 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GKNECEFK_00063 5.3e-137 vanZ - - V - - - VanZ like family
GKNECEFK_00064 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
GKNECEFK_00065 3.26e-274 - - - EGP - - - Major Facilitator
GKNECEFK_00066 7.95e-250 ampC - - V - - - Beta-lactamase
GKNECEFK_00069 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
GKNECEFK_00070 7.02e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
GKNECEFK_00071 6.6e-237 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GKNECEFK_00072 1.24e-198 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GKNECEFK_00073 1.66e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GKNECEFK_00074 5.28e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GKNECEFK_00075 5.87e-166 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
GKNECEFK_00076 4.83e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKNECEFK_00077 2.48e-83 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GKNECEFK_00078 6.55e-120 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKNECEFK_00079 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GKNECEFK_00080 1.48e-221 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GKNECEFK_00081 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GKNECEFK_00082 2.45e-93 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
GKNECEFK_00083 2.54e-42 - - - S - - - Protein of unknown function (DUF1146)
GKNECEFK_00084 4.81e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
GKNECEFK_00085 1.59e-68 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
GKNECEFK_00086 5.13e-46 - - - S - - - Protein of unknown function (DUF2969)
GKNECEFK_00087 1.18e-275 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
GKNECEFK_00088 9.45e-104 uspA - - T - - - universal stress protein
GKNECEFK_00089 1.35e-56 - - - - - - - -
GKNECEFK_00090 1.47e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
GKNECEFK_00091 8.08e-110 - - - S - - - Protein of unknown function (DUF1694)
GKNECEFK_00092 3.07e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GKNECEFK_00093 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GKNECEFK_00094 3.52e-272 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GKNECEFK_00095 3.48e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKNECEFK_00096 2.1e-232 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
GKNECEFK_00097 6.01e-153 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GKNECEFK_00098 3.97e-57 - - - S - - - PD-(D/E)XK nuclease family transposase
GKNECEFK_00099 1.06e-86 - - - S - - - GtrA-like protein
GKNECEFK_00100 1.73e-219 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
GKNECEFK_00101 3.33e-123 - - - S - - - Protein of unknown function (DUF3990)
GKNECEFK_00102 2.09e-59 - - - - - - - -
GKNECEFK_00103 9.25e-13 - - - S - - - PD-(D/E)XK nuclease family transposase
GKNECEFK_00104 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GKNECEFK_00105 3.02e-166 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
GKNECEFK_00106 2.91e-67 - - - - - - - -
GKNECEFK_00107 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GKNECEFK_00108 1.22e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GKNECEFK_00109 1.06e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
GKNECEFK_00110 6.18e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
GKNECEFK_00111 8.26e-226 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
GKNECEFK_00112 8.27e-189 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
GKNECEFK_00113 5.43e-122 mreD - - - ko:K03571 - ko00000,ko03036 -
GKNECEFK_00114 1.4e-09 - - - S - - - Protein of unknown function (DUF4044)
GKNECEFK_00115 1.02e-72 - - - S - - - Protein of unknown function (DUF3397)
GKNECEFK_00116 5.63e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
GKNECEFK_00117 1.49e-223 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GKNECEFK_00118 6.55e-72 ftsL - - D - - - Cell division protein FtsL
GKNECEFK_00119 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GKNECEFK_00120 4.43e-224 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKNECEFK_00121 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GKNECEFK_00122 3.88e-264 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GKNECEFK_00123 3.14e-194 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GKNECEFK_00124 2.29e-315 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GKNECEFK_00125 2.52e-300 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GKNECEFK_00126 1.43e-96 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GKNECEFK_00127 9.86e-60 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
GKNECEFK_00128 8.08e-192 ylmH - - S - - - S4 domain protein
GKNECEFK_00129 6.3e-138 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
GKNECEFK_00130 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GKNECEFK_00131 9.48e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
GKNECEFK_00132 1.27e-134 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
GKNECEFK_00133 6.03e-56 - - - - - - - -
GKNECEFK_00134 2.05e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GKNECEFK_00135 1.33e-275 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
GKNECEFK_00136 2.97e-76 XK27_04120 - - S - - - Putative amino acid metabolism
GKNECEFK_00137 7.72e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GKNECEFK_00138 4.7e-163 pgm - - G - - - Phosphoglycerate mutase family
GKNECEFK_00139 2.31e-148 - - - S - - - repeat protein
GKNECEFK_00140 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GKNECEFK_00141 0.0 - - - L - - - Nuclease-related domain
GKNECEFK_00142 1.75e-211 ytlR - - I - - - Diacylglycerol kinase catalytic domain
GKNECEFK_00143 3.74e-182 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKNECEFK_00144 7.92e-221 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKNECEFK_00145 3.27e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKNECEFK_00146 1.21e-245 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKNECEFK_00147 7.32e-46 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKNECEFK_00148 3.69e-233 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GKNECEFK_00149 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GKNECEFK_00150 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
GKNECEFK_00151 8.29e-75 yloU - - S - - - Asp23 family, cell envelope-related function
GKNECEFK_00152 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
GKNECEFK_00153 2.29e-41 - - - - - - - -
GKNECEFK_00154 1.1e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
GKNECEFK_00155 7.49e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GKNECEFK_00156 1.71e-208 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GKNECEFK_00157 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
GKNECEFK_00158 3.28e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
GKNECEFK_00159 7.82e-311 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GKNECEFK_00160 1.27e-219 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GKNECEFK_00161 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKNECEFK_00162 2.37e-46 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GKNECEFK_00163 5.97e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
GKNECEFK_00164 2.19e-100 - - - S - - - ASCH
GKNECEFK_00165 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
GKNECEFK_00166 7.22e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
GKNECEFK_00167 6.44e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GKNECEFK_00168 1.53e-47 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKNECEFK_00169 1.97e-248 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKNECEFK_00170 7.19e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GKNECEFK_00171 2.78e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GKNECEFK_00172 7.98e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
GKNECEFK_00173 2.11e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKNECEFK_00174 2.14e-257 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GKNECEFK_00175 7.95e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
GKNECEFK_00176 6.82e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
GKNECEFK_00177 5.24e-194 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKNECEFK_00178 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
GKNECEFK_00186 2.45e-147 - - - - - - - -
GKNECEFK_00187 3.76e-87 - - - - - - - -
GKNECEFK_00188 5.94e-148 - - - I - - - Acid phosphatase homologues
GKNECEFK_00189 2.25e-241 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
GKNECEFK_00190 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
GKNECEFK_00191 3.6e-106 - - - C - - - Flavodoxin
GKNECEFK_00192 1.79e-99 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GKNECEFK_00193 1.64e-101 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GKNECEFK_00194 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GKNECEFK_00195 1.23e-54 - - - V ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 HlyD family secretion protein
GKNECEFK_00197 1.5e-27 - - - S - - - Enterocin A Immunity
GKNECEFK_00198 5.34e-77 tnpR1 - - L - - - Resolvase, N terminal domain
GKNECEFK_00199 4.1e-34 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GKNECEFK_00200 7.44e-129 - - - L - - - An automated process has identified a potential problem with this gene model
GKNECEFK_00201 9.33e-06 - - - M - - - Rib/alpha-like repeat
GKNECEFK_00202 4.18e-144 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GKNECEFK_00203 3.61e-60 - - - - - - - -
GKNECEFK_00204 4.53e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
GKNECEFK_00206 3.75e-48 - - - S - - - PFAM Archaeal ATPase
GKNECEFK_00207 6.55e-97 - - - - - - - -
GKNECEFK_00208 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
GKNECEFK_00209 8.26e-290 - - - - - - - -
GKNECEFK_00210 2.38e-05 - - - S - - - Calcineurin-like phosphoesterase
GKNECEFK_00211 2.09e-164 - - - K - - - Probable Zinc-ribbon domain
GKNECEFK_00212 1.78e-148 - - - L - - - Integrase
GKNECEFK_00213 4.02e-91 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
GKNECEFK_00214 5.32e-42 - - - - ko:K18829 - ko00000,ko02048 -
GKNECEFK_00215 6.86e-05 - - - S - - - SLAP domain
GKNECEFK_00216 0.0 - - - M - - - Psort location Cellwall, score
GKNECEFK_00217 7.82e-80 - - - - - - - -
GKNECEFK_00218 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
GKNECEFK_00219 2.14e-312 - - - P - - - P-loop Domain of unknown function (DUF2791)
GKNECEFK_00220 5.53e-173 - - - S - - - TerB-C domain
GKNECEFK_00224 5.75e-152 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
GKNECEFK_00225 6.44e-257 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GKNECEFK_00226 2.25e-137 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
GKNECEFK_00227 4.58e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
GKNECEFK_00228 1.15e-104 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GKNECEFK_00229 3.57e-170 - - - L - - - Phage integrase family
GKNECEFK_00230 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
GKNECEFK_00231 3.22e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GKNECEFK_00232 1.06e-185 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GKNECEFK_00233 5.12e-174 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKNECEFK_00234 5.5e-202 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKNECEFK_00235 1.02e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKNECEFK_00236 2.23e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
GKNECEFK_00237 3.62e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKNECEFK_00238 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GKNECEFK_00239 3.44e-72 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKNECEFK_00240 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
GKNECEFK_00241 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GKNECEFK_00242 3.7e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GKNECEFK_00243 1.25e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GKNECEFK_00244 4.95e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GKNECEFK_00245 2.22e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
GKNECEFK_00246 3.73e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GKNECEFK_00247 2.8e-72 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GKNECEFK_00248 7.18e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GKNECEFK_00249 7.94e-90 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GKNECEFK_00250 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKNECEFK_00251 1.23e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKNECEFK_00252 3.03e-44 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GKNECEFK_00253 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GKNECEFK_00254 1.56e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GKNECEFK_00255 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
GKNECEFK_00256 1.66e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GKNECEFK_00257 3.54e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GKNECEFK_00258 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GKNECEFK_00259 1.14e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GKNECEFK_00260 4.01e-198 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKNECEFK_00261 1.14e-63 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GKNECEFK_00262 4.68e-138 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
GKNECEFK_00263 6.64e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GKNECEFK_00264 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
GKNECEFK_00265 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GKNECEFK_00266 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GKNECEFK_00267 1.47e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GKNECEFK_00268 7.71e-157 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
GKNECEFK_00269 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKNECEFK_00270 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKNECEFK_00271 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GKNECEFK_00272 6.8e-112 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
GKNECEFK_00273 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
GKNECEFK_00274 0.0 ycaM - - E - - - amino acid
GKNECEFK_00275 1.43e-178 - - - S - - - Cysteine-rich secretory protein family
GKNECEFK_00276 7.65e-101 - - - K - - - MerR HTH family regulatory protein
GKNECEFK_00277 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
GKNECEFK_00278 1.43e-309 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
GKNECEFK_00279 7.68e-63 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GKNECEFK_00280 5.01e-150 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
GKNECEFK_00281 6.51e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
GKNECEFK_00282 7.73e-199 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GKNECEFK_00283 9.46e-159 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
GKNECEFK_00284 0.0 - - - - ko:K14201 ko05150,map05150 ko00000,ko00001 -
GKNECEFK_00285 2.9e-11 - - - S - - - Psort location Cytoplasmic, score
GKNECEFK_00288 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
GKNECEFK_00289 2.76e-83 - - - - - - - -
GKNECEFK_00290 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
GKNECEFK_00291 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
GKNECEFK_00292 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
GKNECEFK_00293 2.52e-06 - - - D - - - Domain of Unknown Function (DUF1542)
GKNECEFK_00294 0.0 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 Cation transporter/ATPase, N-terminus
GKNECEFK_00295 4.97e-45 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537,ko:K12952 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
GKNECEFK_00297 2.08e-95 yfhC - - C - - - nitroreductase
GKNECEFK_00298 8.85e-94 - - - S - - - Domain of unknown function (DUF4767)
GKNECEFK_00299 1.43e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GKNECEFK_00300 1.23e-187 - - - S - - - Uncharacterised protein, DegV family COG1307
GKNECEFK_00301 1.94e-130 - - - I - - - PAP2 superfamily
GKNECEFK_00302 4.01e-314 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GKNECEFK_00303 6.21e-153 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
GKNECEFK_00304 1.53e-142 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
GKNECEFK_00305 3.34e-303 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
GKNECEFK_00306 1.02e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GKNECEFK_00307 0.0 qacA - - EGP - - - Major Facilitator
GKNECEFK_00308 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKNECEFK_00309 5.22e-45 ykzG - - S - - - Belongs to the UPF0356 family
GKNECEFK_00310 2.79e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GKNECEFK_00311 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
GKNECEFK_00312 3.91e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GKNECEFK_00313 9.94e-71 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
GKNECEFK_00314 5.21e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
GKNECEFK_00315 7.07e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GKNECEFK_00316 1.42e-244 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
GKNECEFK_00317 2.7e-126 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
GKNECEFK_00318 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GKNECEFK_00319 2.57e-226 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
GKNECEFK_00320 3.64e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
GKNECEFK_00321 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GKNECEFK_00322 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKNECEFK_00323 5.43e-191 - - - - - - - -
GKNECEFK_00324 5.76e-287 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GKNECEFK_00325 2.56e-291 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GKNECEFK_00326 3.04e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GKNECEFK_00327 1.59e-136 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
GKNECEFK_00328 2.58e-48 potE - - E - - - Amino Acid
GKNECEFK_00329 1.27e-220 potE - - E - - - Amino Acid
GKNECEFK_00330 6.25e-246 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GKNECEFK_00331 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GKNECEFK_00332 1.39e-312 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GKNECEFK_00333 8.62e-105 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GKNECEFK_00334 3.29e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GKNECEFK_00335 3.66e-225 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GKNECEFK_00336 6.89e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GKNECEFK_00337 9.03e-277 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKNECEFK_00338 2.48e-252 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GKNECEFK_00339 2.79e-165 - - - S - - - SLAP domain
GKNECEFK_00340 1.05e-54 - - - S - - - Protein of unknown function (DUF2922)
GKNECEFK_00341 1.21e-40 - - - - - - - -
GKNECEFK_00342 2.77e-25 - - - - - - - -
GKNECEFK_00343 4.95e-164 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
GKNECEFK_00344 4.77e-248 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
GKNECEFK_00345 1.28e-226 - - - S - - - PFAM Archaeal ATPase
GKNECEFK_00346 1.86e-91 - - - S ko:K07133 - ko00000 cog cog1373
GKNECEFK_00347 6.67e-210 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKNECEFK_00348 2.73e-92 - - - S - - - Domain of unknown function (DUF3284)
GKNECEFK_00349 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKNECEFK_00350 2.3e-169 - - - K ko:K03492 - ko00000,ko03000 UTRA
GKNECEFK_00351 3.1e-127 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
GKNECEFK_00352 1.59e-259 pbpX1 - - V - - - Beta-lactamase
GKNECEFK_00353 1.12e-149 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
GKNECEFK_00354 1.12e-104 yvbK - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKNECEFK_00355 1.76e-171 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GKNECEFK_00356 2.08e-164 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GKNECEFK_00358 4.17e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
GKNECEFK_00359 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GKNECEFK_00360 4.73e-72 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
GKNECEFK_00361 1.14e-261 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GKNECEFK_00362 1.66e-84 - - - S - - - RelE toxin of RelE / RelB toxin-antitoxin system
GKNECEFK_00363 8.4e-64 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
GKNECEFK_00365 2.79e-145 - - - - - - - -
GKNECEFK_00366 9.07e-51 - - - S - - - CRISPR-associated protein (Cas_Csn2)
GKNECEFK_00367 4.67e-54 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GKNECEFK_00368 1.44e-164 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GKNECEFK_00369 2.47e-104 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GKNECEFK_00370 1.5e-93 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GKNECEFK_00371 4.02e-11 - - - - - - - -
GKNECEFK_00372 1.02e-75 - - - - - - - -
GKNECEFK_00373 6.84e-70 - - - - - - - -
GKNECEFK_00375 4.4e-165 - - - S - - - PAS domain
GKNECEFK_00377 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
GKNECEFK_00378 2.57e-61 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
GKNECEFK_00379 2.64e-49 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
GKNECEFK_00380 2.52e-76 - - - - - - - -
GKNECEFK_00381 0.0 - - - S - - - ABC transporter
GKNECEFK_00382 7.35e-174 - - - S - - - Putative threonine/serine exporter
GKNECEFK_00383 7.36e-109 - - - S - - - Threonine/Serine exporter, ThrE
GKNECEFK_00384 1.58e-143 - - - S - - - Peptidase_C39 like family
GKNECEFK_00385 1.16e-101 - - - - - - - -
GKNECEFK_00386 1.96e-226 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKNECEFK_00387 4.75e-101 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
GKNECEFK_00388 5.48e-283 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GKNECEFK_00389 8.77e-144 - - - - - - - -
GKNECEFK_00390 0.0 - - - S - - - O-antigen ligase like membrane protein
GKNECEFK_00391 4.52e-56 - - - - - - - -
GKNECEFK_00392 4.26e-115 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
GKNECEFK_00393 1.31e-117 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
GKNECEFK_00394 1.28e-174 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
GKNECEFK_00395 1.73e-167 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
GKNECEFK_00396 1.22e-53 - - - - - - - -
GKNECEFK_00398 2.54e-223 - - - S - - - Cysteine-rich secretory protein family
GKNECEFK_00399 2.86e-286 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GKNECEFK_00401 1.21e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GKNECEFK_00402 1.3e-185 epsB - - M - - - biosynthesis protein
GKNECEFK_00403 2.28e-159 ywqD - - D - - - Capsular exopolysaccharide family
GKNECEFK_00404 2.22e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
GKNECEFK_00405 1.14e-150 epsE2 - - M - - - Bacterial sugar transferase
GKNECEFK_00406 9.92e-152 cps3J - - M - - - Domain of unknown function (DUF4422)
GKNECEFK_00408 1.65e-101 epsIIG 1.1.1.133 - S ko:K00067,ko:K07011 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Glycosyltransferase, group 2 family protein
GKNECEFK_00409 9.04e-92 - - - M - - - Glycosyltransferase, group 1 family protein
GKNECEFK_00410 1.04e-98 - - - M - - - Glycosyl transferase family 2
GKNECEFK_00411 1.37e-249 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
GKNECEFK_00412 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
GKNECEFK_00413 2.48e-196 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
GKNECEFK_00414 5.24e-187 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKNECEFK_00415 3.83e-178 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKNECEFK_00416 2.89e-151 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GKNECEFK_00417 3.31e-154 - - - K - - - helix_turn_helix, mercury resistance
GKNECEFK_00418 3.82e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GKNECEFK_00419 1.8e-36 - - - M - - - LysM domain protein
GKNECEFK_00420 9.44e-63 - - - M - - - LysM domain protein
GKNECEFK_00421 9.11e-110 - - - C - - - Aldo keto reductase
GKNECEFK_00422 9.4e-232 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
GKNECEFK_00425 4.13e-83 - - - - - - - -
GKNECEFK_00426 3.56e-47 - - - - - - - -
GKNECEFK_00427 4.22e-288 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKNECEFK_00428 4.06e-39 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKNECEFK_00429 1.31e-56 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKNECEFK_00430 8.72e-258 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKNECEFK_00431 1.81e-89 - - - S - - - Protein of unknown function (DUF3021)
GKNECEFK_00432 4.48e-178 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GKNECEFK_00433 9.37e-144 - - - S ko:K01992 - ko00000,ko00002,ko02000 domain protein
GKNECEFK_00434 1.96e-127 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
GKNECEFK_00435 8.97e-47 - - - - - - - -
GKNECEFK_00436 5.94e-200 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
GKNECEFK_00437 6.13e-110 - - - K - - - Acetyltransferase (GNAT) domain
GKNECEFK_00438 1.05e-176 - - - F - - - Phosphorylase superfamily
GKNECEFK_00439 6.64e-185 - - - F - - - Phosphorylase superfamily
GKNECEFK_00440 2.16e-193 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
GKNECEFK_00441 8.28e-102 - - - S - - - helix_turn_helix, Deoxyribose operon repressor
GKNECEFK_00442 6.72e-177 - - - EP - - - Plasmid replication protein
GKNECEFK_00443 4.63e-32 - - - - - - - -
GKNECEFK_00444 6.56e-86 sagB - - C - - - Nitroreductase family
GKNECEFK_00446 8.25e-65 - - - V ko:K01990,ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
GKNECEFK_00447 9.75e-80 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GKNECEFK_00449 3.5e-280 - - - L - - - Belongs to the 'phage' integrase family
GKNECEFK_00450 4.04e-36 - - - - - - - -
GKNECEFK_00451 1.33e-72 - - - - - - - -
GKNECEFK_00452 1.74e-185 - - - S - - - Replication initiation factor
GKNECEFK_00453 2.67e-180 - - - D - - - Ftsk spoiiie family protein
GKNECEFK_00454 6.59e-115 - - - - - - - -
GKNECEFK_00455 4.95e-98 - - - - - - - -
GKNECEFK_00456 6.48e-167 - - - K - - - Helix-turn-helix XRE-family like proteins
GKNECEFK_00458 3.92e-153 - - - S ko:K07507 - ko00000,ko02000 MgtC family
GKNECEFK_00459 5.56e-287 - - - I - - - Protein of unknown function (DUF2974)
GKNECEFK_00460 2.26e-31 - - - S - - - Transglycosylase associated protein
GKNECEFK_00461 3.81e-18 - - - S - - - CsbD-like
GKNECEFK_00462 4.76e-213 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
GKNECEFK_00463 1.23e-170 - - - V - - - ABC transporter transmembrane region
GKNECEFK_00464 2.26e-215 degV1 - - S - - - DegV family
GKNECEFK_00465 5.56e-217 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
GKNECEFK_00466 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
GKNECEFK_00467 3.87e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
GKNECEFK_00468 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
GKNECEFK_00469 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GKNECEFK_00470 4.83e-104 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GKNECEFK_00471 6.72e-66 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
GKNECEFK_00472 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKNECEFK_00473 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKNECEFK_00474 4.22e-267 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GKNECEFK_00475 1.13e-48 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
GKNECEFK_00476 8.11e-245 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GKNECEFK_00477 9.14e-317 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GKNECEFK_00478 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
GKNECEFK_00479 8.64e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GKNECEFK_00480 3.17e-224 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
GKNECEFK_00481 1.78e-25 - - - - - - - -
GKNECEFK_00482 3.96e-15 B4168_4126 - - L ko:K07493 - ko00000 MULE transposase domain
GKNECEFK_00484 8.51e-205 - - - - - - - -
GKNECEFK_00485 1.67e-219 - - - - - - - -
GKNECEFK_00487 4.01e-184 - - - - - - - -
GKNECEFK_00488 4.4e-215 - - - - - - - -
GKNECEFK_00489 8.08e-108 - - - S - - - PFAM Archaeal ATPase
GKNECEFK_00490 1.32e-105 - - - S - - - PFAM Archaeal ATPase
GKNECEFK_00491 7.02e-36 - - - - - - - -
GKNECEFK_00497 1.24e-75 - - - S - - - Peptidase propeptide and YPEB domain
GKNECEFK_00498 2.46e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKNECEFK_00499 7.92e-218 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GKNECEFK_00500 1.13e-126 - - - E - - - GDSL-like Lipase/Acylhydrolase
GKNECEFK_00501 3.33e-97 yjcF - - S - - - Acetyltransferase (GNAT) domain
GKNECEFK_00502 7.09e-184 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GKNECEFK_00503 4.85e-136 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
GKNECEFK_00504 3e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GKNECEFK_00505 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GKNECEFK_00506 1.47e-158 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
GKNECEFK_00507 7.53e-163 gpm2 - - G - - - Phosphoglycerate mutase family
GKNECEFK_00508 1.08e-307 - - - S - - - response to antibiotic
GKNECEFK_00509 1.56e-161 - - - - - - - -
GKNECEFK_00510 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GKNECEFK_00511 7.34e-86 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
GKNECEFK_00512 5.1e-57 - - - - - - - -
GKNECEFK_00513 6.6e-14 - - - - - - - -
GKNECEFK_00514 4.71e-239 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
GKNECEFK_00515 2.89e-176 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
GKNECEFK_00516 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
GKNECEFK_00517 8.75e-197 - - - - - - - -
GKNECEFK_00518 3.32e-13 - - - - - - - -
GKNECEFK_00519 5.45e-121 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GKNECEFK_00520 5.6e-135 - - - K ko:K06977 - ko00000 acetyltransferase
GKNECEFK_00523 4.92e-20 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
GKNECEFK_00524 1.23e-58 - - - S - - - polysaccharide biosynthetic process
GKNECEFK_00525 4.57e-135 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GKNECEFK_00526 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GKNECEFK_00527 7.56e-125 pbpX1 - - V - - - Beta-lactamase
GKNECEFK_00528 7.76e-317 - - - I - - - Protein of unknown function (DUF2974)
GKNECEFK_00529 1.14e-208 - - - K ko:K03484 - ko00000,ko03000 Periplasmic binding protein domain
GKNECEFK_00530 2.14e-48 - - - - - - - -
GKNECEFK_00532 1.28e-162 sagD - - S - - - YcaO cyclodehydratase, ATP-ad Mg2+-binding
GKNECEFK_00533 2.14e-103 - - - - - - - -
GKNECEFK_00534 2.28e-76 eriC - - P ko:K03281 - ko00000 chloride
GKNECEFK_00535 1.48e-136 - - - L - - - PFAM Integrase catalytic
GKNECEFK_00536 5.73e-153 - - - - - - - -
GKNECEFK_00537 5.46e-182 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GKNECEFK_00538 2.74e-06 - - - S - - - PFAM Archaeal ATPase
GKNECEFK_00539 1.15e-64 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GKNECEFK_00540 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GKNECEFK_00543 2.9e-48 - - - - - - - -
GKNECEFK_00544 1.24e-08 - - - - - - - -
GKNECEFK_00545 4.83e-136 pncA - - Q - - - Isochorismatase family
GKNECEFK_00546 8.12e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GKNECEFK_00547 3.39e-185 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GKNECEFK_00548 5.62e-95 yslB - - S - - - Protein of unknown function (DUF2507)
GKNECEFK_00549 2.34e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GKNECEFK_00550 5.37e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GKNECEFK_00551 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GKNECEFK_00552 1.18e-66 yrzB - - S - - - Belongs to the UPF0473 family
GKNECEFK_00553 9.37e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GKNECEFK_00554 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
GKNECEFK_00555 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GKNECEFK_00556 1.26e-303 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GKNECEFK_00557 3.16e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
GKNECEFK_00558 6.15e-268 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKNECEFK_00559 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GKNECEFK_00560 7.58e-69 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GKNECEFK_00561 1.39e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GKNECEFK_00562 3.89e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GKNECEFK_00563 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GKNECEFK_00564 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKNECEFK_00565 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GKNECEFK_00566 1.06e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GKNECEFK_00567 2.79e-102 - - - - - - - -
GKNECEFK_00568 2.14e-231 - - - M - - - CHAP domain
GKNECEFK_00569 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKNECEFK_00570 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
GKNECEFK_00571 2.14e-234 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
GKNECEFK_00573 1.14e-130 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
GKNECEFK_00575 6.33e-221 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Beta-lactamase superfamily domain
GKNECEFK_00576 4.93e-80 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GKNECEFK_00577 9.13e-157 - - - L - - - PFAM transposase IS116 IS110 IS902
GKNECEFK_00578 0.0 - - - L - - - Transposase DDE domain
GKNECEFK_00579 3.24e-290 - - - L - - - COG3547 Transposase and inactivated derivatives
GKNECEFK_00580 4.66e-277 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GKNECEFK_00581 7.7e-126 - - - L - - - Helix-turn-helix domain
GKNECEFK_00582 7.32e-157 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GKNECEFK_00583 6.74e-269 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GKNECEFK_00584 5.83e-67 - - - L - - - PFAM transposase, IS4 family protein
GKNECEFK_00585 7.06e-114 - - - L - - - PFAM transposase, IS4 family protein
GKNECEFK_00586 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GKNECEFK_00587 8.59e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
GKNECEFK_00588 0.0 yhdP - - S - - - Transporter associated domain
GKNECEFK_00589 2.14e-154 - - - C - - - nitroreductase
GKNECEFK_00590 1.76e-52 - - - - - - - -
GKNECEFK_00591 1.96e-113 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GKNECEFK_00592 1.52e-103 - - - - - - - -
GKNECEFK_00593 6.89e-190 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
GKNECEFK_00594 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
GKNECEFK_00595 7.44e-189 - - - S - - - hydrolase
GKNECEFK_00596 1.85e-205 - - - S - - - Phospholipase, patatin family
GKNECEFK_00597 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
GKNECEFK_00598 4.44e-174 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
GKNECEFK_00599 2.9e-79 - - - S - - - Enterocin A Immunity
GKNECEFK_00600 3.18e-198 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
GKNECEFK_00601 6.63e-174 gntR - - K - - - UbiC transcription regulator-associated domain protein
GKNECEFK_00602 1.01e-222 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
GKNECEFK_00603 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
GKNECEFK_00604 1.82e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GKNECEFK_00605 8.52e-215 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKNECEFK_00606 7.29e-209 - - - C - - - Domain of unknown function (DUF4931)
GKNECEFK_00607 2.2e-308 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKNECEFK_00608 3.52e-296 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
GKNECEFK_00609 2.09e-110 - - - - - - - -
GKNECEFK_00610 1.08e-229 - - - L - - - DDE superfamily endonuclease
GKNECEFK_00611 1.05e-75 - - - S - - - SIR2-like domain
GKNECEFK_00612 5.93e-50 eriC - - P ko:K03281 - ko00000 chloride
GKNECEFK_00613 6.55e-76 eriC - - P ko:K03281 - ko00000 chloride
GKNECEFK_00614 1.45e-34 - - - K - - - FCD
GKNECEFK_00615 6.94e-202 - - - K - - - Helix-turn-helix XRE-family like proteins
GKNECEFK_00616 1.45e-255 - - - S - - - Domain of unknown function (DUF389)
GKNECEFK_00617 2.22e-296 - - - E ko:K03294 - ko00000 amino acid
GKNECEFK_00618 6.18e-289 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
GKNECEFK_00619 3.87e-73 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GKNECEFK_00620 3.4e-196 B4168_4126 - - L ko:K07493 - ko00000 Transposase
GKNECEFK_00621 1.57e-199 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
GKNECEFK_00622 2.36e-45 - - - L - - - An automated process has identified a potential problem with this gene model
GKNECEFK_00623 3.82e-216 - - - S - - - Uncharacterised protein family (UPF0236)
GKNECEFK_00624 4.37e-132 - - - GM - - - NmrA-like family
GKNECEFK_00625 5.5e-154 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GKNECEFK_00626 1.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GKNECEFK_00627 5.1e-211 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GKNECEFK_00628 2.9e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GKNECEFK_00629 2.22e-231 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
GKNECEFK_00630 8.31e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GKNECEFK_00631 4.22e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GKNECEFK_00632 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GKNECEFK_00633 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GKNECEFK_00634 6.79e-190 - - - U ko:K05340 - ko00000,ko02000 sugar transport
GKNECEFK_00635 8.74e-62 - - - - - - - -
GKNECEFK_00636 2.88e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
GKNECEFK_00637 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GKNECEFK_00638 1.02e-29 - - - S - - - Alpha beta hydrolase
GKNECEFK_00639 2.48e-80 - - - S - - - Alpha beta hydrolase
GKNECEFK_00640 8.51e-50 - - - - - - - -
GKNECEFK_00641 4.3e-66 - - - - - - - -
GKNECEFK_00642 1.14e-189 supH - - S - - - haloacid dehalogenase-like hydrolase
GKNECEFK_00643 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GKNECEFK_00644 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
GKNECEFK_00645 1.82e-86 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
GKNECEFK_00646 1.23e-227 lipA - - I - - - Carboxylesterase family
GKNECEFK_00648 1.16e-269 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GKNECEFK_00649 8.57e-202 cinI - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
GKNECEFK_00650 0.0 - - - S - - - Predicted membrane protein (DUF2207)
GKNECEFK_00651 2.07e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
GKNECEFK_00652 2.25e-72 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
GKNECEFK_00653 4.32e-63 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
GKNECEFK_00654 2.95e-123 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GKNECEFK_00655 1.83e-103 - - - S - - - AAA domain
GKNECEFK_00656 9.82e-80 - - - F - - - NUDIX domain
GKNECEFK_00657 7.55e-53 - - - S - - - Transglycosylase associated protein
GKNECEFK_00658 1.33e-92 - - - - - - - -
GKNECEFK_00659 8.23e-09 - - - M - - - Mycoplasma protein of unknown function, DUF285
GKNECEFK_00660 5.57e-22 - - - S - - - Protein of unknown function (DUF1275)
GKNECEFK_00661 4.52e-114 - - - S - - - Protein of unknown function (DUF1275)
GKNECEFK_00662 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GKNECEFK_00663 2.53e-56 - - - - - - - -
GKNECEFK_00664 1.37e-219 - - - GK - - - ROK family
GKNECEFK_00665 5.4e-226 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKNECEFK_00666 0.0 - - - S - - - SLAP domain
GKNECEFK_00667 5.52e-113 - - - - - - - -
GKNECEFK_00668 3.12e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GKNECEFK_00669 3.39e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
GKNECEFK_00670 9.99e-53 veg - - S - - - Biofilm formation stimulator VEG
GKNECEFK_00671 2.56e-193 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GKNECEFK_00672 5.17e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GKNECEFK_00673 2.72e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
GKNECEFK_00674 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKNECEFK_00675 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GKNECEFK_00676 6.84e-173 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GKNECEFK_00677 4.57e-135 - - - S ko:K06872 - ko00000 TPM domain
GKNECEFK_00678 1.5e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
GKNECEFK_00679 4.07e-245 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GKNECEFK_00680 7.04e-145 - - - E - - - Belongs to the SOS response-associated peptidase family
GKNECEFK_00682 1.17e-143 - - - - - - - -
GKNECEFK_00683 8.08e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKNECEFK_00684 3.4e-93 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GKNECEFK_00685 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GKNECEFK_00686 6.54e-222 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKNECEFK_00687 7.1e-252 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKNECEFK_00688 7.82e-240 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKNECEFK_00689 1.34e-191 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKNECEFK_00690 2.64e-266 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKNECEFK_00691 2.58e-39 - - - L - - - Transposase and inactivated derivatives, IS30 family
GKNECEFK_00692 2.09e-105 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GKNECEFK_00693 6.21e-161 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
GKNECEFK_00694 2.99e-114 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GKNECEFK_00696 1.22e-192 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
GKNECEFK_00700 8.34e-116 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_00701 4.03e-75 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GKNECEFK_00702 3.85e-97 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GKNECEFK_00703 9.69e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GKNECEFK_00704 8.93e-180 - - - S - - - haloacid dehalogenase-like hydrolase
GKNECEFK_00705 2.6e-93 - - - - - - - -
GKNECEFK_00706 1.06e-159 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
GKNECEFK_00707 9.85e-154 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
GKNECEFK_00708 1.15e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GKNECEFK_00709 3.08e-205 - - - S - - - Aldo/keto reductase family
GKNECEFK_00710 3.63e-221 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GKNECEFK_00711 8.8e-262 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GKNECEFK_00712 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
GKNECEFK_00713 4.57e-232 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
GKNECEFK_00714 1.97e-255 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
GKNECEFK_00715 5.9e-130 - - - S - - - ECF transporter, substrate-specific component
GKNECEFK_00716 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GKNECEFK_00717 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_00718 5.14e-248 - - - S - - - DUF218 domain
GKNECEFK_00719 3.43e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GKNECEFK_00720 1.49e-141 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
GKNECEFK_00721 3.62e-202 - - - EGP - - - Major facilitator Superfamily
GKNECEFK_00722 1.05e-67 - - - - - - - -
GKNECEFK_00723 1.91e-200 mutR - - K - - - Helix-turn-helix XRE-family like proteins
GKNECEFK_00724 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
GKNECEFK_00725 1.68e-55 yoeB - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
GKNECEFK_00726 2.49e-63 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
GKNECEFK_00727 5.71e-263 napA - - P - - - Sodium/hydrogen exchanger family
GKNECEFK_00728 0.0 cadA - - P - - - P-type ATPase
GKNECEFK_00729 3.41e-107 ykuL - - S - - - (CBS) domain
GKNECEFK_00730 5.11e-265 - - - S - - - Membrane
GKNECEFK_00731 1.42e-58 - - - - - - - -
GKNECEFK_00732 1.3e-26 - - - S - - - D-Ala-teichoic acid biosynthesis protein
GKNECEFK_00733 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKNECEFK_00734 2.95e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
GKNECEFK_00735 4.98e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKNECEFK_00736 6.8e-316 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GKNECEFK_00737 1.97e-227 pbpX2 - - V - - - Beta-lactamase
GKNECEFK_00738 2.5e-172 - - - S - - - Protein of unknown function (DUF975)
GKNECEFK_00739 1.34e-183 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GKNECEFK_00740 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GKNECEFK_00741 1.96e-49 - - - - - - - -
GKNECEFK_00742 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
GKNECEFK_00743 1.68e-161 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_00744 3.09e-304 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKNECEFK_00745 7.86e-212 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GKNECEFK_00746 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
GKNECEFK_00747 5.08e-149 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GKNECEFK_00748 2.58e-310 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GKNECEFK_00749 5.27e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
GKNECEFK_00750 6.36e-173 - - - S - - - PFAM Archaeal ATPase
GKNECEFK_00751 1.95e-221 - - - V - - - HNH endonuclease
GKNECEFK_00753 6.65e-179 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
GKNECEFK_00754 6.45e-291 - - - E - - - amino acid
GKNECEFK_00755 5.12e-242 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
GKNECEFK_00756 1.84e-263 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
GKNECEFK_00759 1.35e-238 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKNECEFK_00760 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GKNECEFK_00761 7.13e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GKNECEFK_00762 9.91e-150 - 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
GKNECEFK_00763 9.67e-104 - - - - - - - -
GKNECEFK_00764 6.74e-309 cpdA - - S - - - Calcineurin-like phosphoesterase
GKNECEFK_00765 1.68e-277 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
GKNECEFK_00766 1.85e-90 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GKNECEFK_00767 1.18e-139 ypsA - - S - - - Belongs to the UPF0398 family
GKNECEFK_00768 8.47e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GKNECEFK_00769 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
GKNECEFK_00770 5.5e-148 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GKNECEFK_00771 6.91e-149 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
GKNECEFK_00772 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
GKNECEFK_00773 9.62e-116 ypmB - - S - - - Protein conserved in bacteria
GKNECEFK_00774 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
GKNECEFK_00775 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
GKNECEFK_00776 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GKNECEFK_00777 3.02e-173 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
GKNECEFK_00778 5.87e-228 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
GKNECEFK_00779 6.67e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
GKNECEFK_00780 4.87e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GKNECEFK_00781 1.28e-150 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
GKNECEFK_00782 9.1e-317 rsmF - - J - - - NOL1 NOP2 sun family protein
GKNECEFK_00783 3.47e-19 - - - - ko:K07473 - ko00000,ko02048 -
GKNECEFK_00784 1.86e-114 ymdB - - S - - - Macro domain protein
GKNECEFK_00786 2.12e-86 - - - L - - - An automated process has identified a potential problem with this gene model
GKNECEFK_00787 3.15e-259 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKNECEFK_00788 6.1e-228 yvdE - - K - - - helix_turn _helix lactose operon repressor
GKNECEFK_00789 7.48e-188 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GKNECEFK_00790 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GKNECEFK_00791 3.66e-186 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GKNECEFK_00792 7.08e-248 - - - G - - - Transmembrane secretion effector
GKNECEFK_00793 5.63e-171 - - - V - - - ABC transporter transmembrane region
GKNECEFK_00794 3.65e-285 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GKNECEFK_00795 1.83e-91 - - - V - - - ABC transporter transmembrane region
GKNECEFK_00796 6.69e-84 - - - L - - - RelB antitoxin
GKNECEFK_00797 1.51e-168 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
GKNECEFK_00798 8.6e-108 - - - M - - - NlpC/P60 family
GKNECEFK_00801 1.02e-200 - - - - - - - -
GKNECEFK_00802 1.03e-07 - - - - - - - -
GKNECEFK_00803 5.51e-47 - - - - - - - -
GKNECEFK_00804 4.48e-206 - - - EG - - - EamA-like transporter family
GKNECEFK_00805 3.18e-209 - - - EG - - - EamA-like transporter family
GKNECEFK_00806 3.75e-178 yicL - - EG - - - EamA-like transporter family
GKNECEFK_00807 1.32e-137 - - - - - - - -
GKNECEFK_00808 9.07e-143 - - - - - - - -
GKNECEFK_00809 1.84e-238 - - - S - - - DUF218 domain
GKNECEFK_00810 0.0 yheS_2 - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
GKNECEFK_00811 6.77e-111 - - - - - - - -
GKNECEFK_00812 1.09e-74 - - - - - - - -
GKNECEFK_00813 7.26e-35 - - - S - - - Protein conserved in bacteria
GKNECEFK_00814 2.27e-71 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
GKNECEFK_00819 3.75e-278 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
GKNECEFK_00820 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
GKNECEFK_00821 8.08e-201 - - - I - - - alpha/beta hydrolase fold
GKNECEFK_00822 2.23e-166 yibF - - S - - - overlaps another CDS with the same product name
GKNECEFK_00823 1.69e-258 yibE - - S - - - overlaps another CDS with the same product name
GKNECEFK_00824 2.45e-164 - - - - - - - -
GKNECEFK_00825 2.43e-263 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GKNECEFK_00826 7.36e-291 - - - S - - - Cysteine-rich secretory protein family
GKNECEFK_00827 1.01e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_00828 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
GKNECEFK_00829 1.11e-177 - - - - - - - -
GKNECEFK_00830 8.37e-161 - - - K - - - Bacterial regulatory proteins, tetR family
GKNECEFK_00831 1.76e-233 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKNECEFK_00832 2.32e-47 - - - - - - - -
GKNECEFK_00833 1.63e-180 - - - L - - - An automated process has identified a potential problem with this gene model
GKNECEFK_00834 5.29e-164 - - - S - - - Alpha/beta hydrolase family
GKNECEFK_00835 2.62e-199 epsV - - S - - - glycosyl transferase family 2
GKNECEFK_00836 9.18e-187 - - - S - - - Protein of unknown function (DUF1002)
GKNECEFK_00837 5.07e-190 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKNECEFK_00838 1.24e-232 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
GKNECEFK_00839 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKNECEFK_00840 2.29e-112 - - - - - - - -
GKNECEFK_00844 3.11e-13 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GKNECEFK_00845 1.87e-290 - - - S - - - Putative peptidoglycan binding domain
GKNECEFK_00846 5.74e-108 - - - K - - - Acetyltransferase (GNAT) domain
GKNECEFK_00847 0.0 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GKNECEFK_00848 6.84e-243 - - - L ko:K07478 - ko00000 AAA C-terminal domain
GKNECEFK_00849 1.12e-85 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GKNECEFK_00850 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKNECEFK_00851 4.21e-129 treR - - K ko:K03486 - ko00000,ko03000 UTRA
GKNECEFK_00852 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
GKNECEFK_00853 1.28e-168 - - - L - - - PFAM transposase IS116 IS110 IS902
GKNECEFK_00855 1.65e-303 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKNECEFK_00856 1.43e-80 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
GKNECEFK_00857 5.93e-302 XK27_01810 - - S - - - Calcineurin-like phosphoesterase
GKNECEFK_00859 0.0 - - - S - - - SLAP domain
GKNECEFK_00860 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
GKNECEFK_00861 1.35e-208 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
GKNECEFK_00863 1.07e-110 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GKNECEFK_00864 1.61e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GKNECEFK_00865 9.32e-189 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
GKNECEFK_00866 5.31e-149 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
GKNECEFK_00867 6.15e-36 - - - - - - - -
GKNECEFK_00868 1.08e-117 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GKNECEFK_00869 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKNECEFK_00870 1.12e-136 - - - M - - - family 8
GKNECEFK_00871 1.15e-47 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
GKNECEFK_00872 6.31e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GKNECEFK_00873 9.21e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GKNECEFK_00874 1.18e-46 - - - S - - - Protein of unknown function (DUF2508)
GKNECEFK_00875 1.15e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GKNECEFK_00876 1.58e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
GKNECEFK_00877 4.86e-198 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GKNECEFK_00878 1.4e-80 yabA - - L - - - Involved in initiation control of chromosome replication
GKNECEFK_00879 3.05e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GKNECEFK_00880 4.27e-167 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
GKNECEFK_00881 8.72e-111 - - - S - - - ECF transporter, substrate-specific component
GKNECEFK_00882 3.69e-171 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
GKNECEFK_00883 3.93e-125 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
GKNECEFK_00884 5.79e-247 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GKNECEFK_00885 1.28e-311 - - - L ko:K07484 - ko00000 Transposase IS66 family
GKNECEFK_00886 5.51e-46 - - - S - - - Transposase C of IS166 homeodomain
GKNECEFK_00887 4.01e-84 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
GKNECEFK_00888 9.48e-31 - - - - - - - -
GKNECEFK_00889 3.06e-53 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GKNECEFK_00890 6.43e-230 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GKNECEFK_00891 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GKNECEFK_00892 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
GKNECEFK_00893 8.74e-146 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GKNECEFK_00894 7.74e-61 - - - - - - - -
GKNECEFK_00895 1.04e-48 ybcH - - D ko:K06889 - ko00000 Alpha beta
GKNECEFK_00896 1.94e-150 ybcH - - D ko:K06889 - ko00000 Alpha beta
GKNECEFK_00897 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKNECEFK_00898 2.79e-185 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
GKNECEFK_00899 1.74e-111 - - - - - - - -
GKNECEFK_00900 7.76e-98 - - - - - - - -
GKNECEFK_00901 1.76e-181 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
GKNECEFK_00902 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GKNECEFK_00903 5.93e-60 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
GKNECEFK_00904 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
GKNECEFK_00905 2.6e-37 - - - - - - - -
GKNECEFK_00906 1.29e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
GKNECEFK_00907 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKNECEFK_00908 6.28e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GKNECEFK_00909 1.5e-178 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GKNECEFK_00910 2.63e-205 coiA - - S ko:K06198 - ko00000 Competence protein
GKNECEFK_00911 5.74e-148 yjbH - - Q - - - Thioredoxin
GKNECEFK_00912 2.44e-143 - - - S - - - CYTH
GKNECEFK_00913 1.7e-147 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
GKNECEFK_00914 1.91e-195 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKNECEFK_00915 7.96e-221 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GKNECEFK_00916 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
GKNECEFK_00917 3.77e-122 - - - S - - - SNARE associated Golgi protein
GKNECEFK_00918 2.85e-54 - - - - - - - -
GKNECEFK_00919 3.6e-101 - - - K - - - DNA-templated transcription, initiation
GKNECEFK_00921 4.56e-191 - - - S - - - PD-(D/E)XK nuclease family transposase
GKNECEFK_00923 6.35e-28 - - - S - - - PD-(D/E)XK nuclease family transposase
GKNECEFK_00924 3.83e-136 - - - S - - - SLAP domain
GKNECEFK_00926 2.09e-286 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKNECEFK_00927 7.32e-232 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
GKNECEFK_00928 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
GKNECEFK_00929 2.47e-138 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GKNECEFK_00930 1.68e-207 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
GKNECEFK_00931 1.98e-168 - - - - - - - -
GKNECEFK_00932 1.48e-150 - - - - - - - -
GKNECEFK_00933 4.51e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKNECEFK_00934 5.18e-128 - - - G - - - Aldose 1-epimerase
GKNECEFK_00935 1.69e-257 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GKNECEFK_00936 1.03e-145 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GKNECEFK_00937 0.0 XK27_08315 - - M - - - Sulfatase
GKNECEFK_00938 3.89e-129 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GKNECEFK_00939 7.86e-138 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
GKNECEFK_00940 5.02e-180 blpT - - - - - - -
GKNECEFK_00944 7.87e-30 - - - - - - - -
GKNECEFK_00945 4.74e-107 - - - - - - - -
GKNECEFK_00946 6.32e-42 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
GKNECEFK_00947 2.52e-32 - - - - - - - -
GKNECEFK_00948 3.41e-88 - - - - - - - -
GKNECEFK_00949 3.09e-212 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_00950 6.39e-279 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GKNECEFK_00951 3.14e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
GKNECEFK_00952 2.18e-215 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GKNECEFK_00953 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
GKNECEFK_00954 4.47e-56 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
GKNECEFK_00955 9.9e-209 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GKNECEFK_00956 1.63e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GKNECEFK_00957 1.59e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
GKNECEFK_00958 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GKNECEFK_00959 6.6e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GKNECEFK_00960 2.04e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
GKNECEFK_00961 0.000868 - - - - - - - -
GKNECEFK_00962 1.13e-35 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
GKNECEFK_00964 3.65e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKNECEFK_00965 4.29e-122 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKNECEFK_00966 7.99e-186 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKNECEFK_00967 2.8e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_00968 2.72e-60 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
GKNECEFK_00969 5.43e-50 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
GKNECEFK_00970 8.41e-314 - - - G - - - MFS/sugar transport protein
GKNECEFK_00971 1.72e-129 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
GKNECEFK_00972 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
GKNECEFK_00973 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_00974 2.53e-106 - - - K - - - Transcriptional regulator, MarR family
GKNECEFK_00975 2.05e-188 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKNECEFK_00976 1.07e-165 - - - F - - - glutamine amidotransferase
GKNECEFK_00977 3.41e-312 steT - - E ko:K03294 - ko00000 amino acid
GKNECEFK_00978 3.97e-33 steT - - E ko:K03294 - ko00000 amino acid
GKNECEFK_00979 1.11e-256 steT - - E ko:K03294 - ko00000 amino acid
GKNECEFK_00980 1.53e-176 - - - - - - - -
GKNECEFK_00981 6.07e-223 ydhF - - S - - - Aldo keto reductase
GKNECEFK_00982 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
GKNECEFK_00983 2.33e-230 pepA - - E - - - M42 glutamyl aminopeptidase
GKNECEFK_00984 3.49e-36 - - - - - - - -
GKNECEFK_00985 3.85e-193 - - - - - - - -
GKNECEFK_00986 2.54e-176 - - - - - - - -
GKNECEFK_00987 1.65e-180 - - - - - - - -
GKNECEFK_00988 1.55e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GKNECEFK_00989 1.25e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
GKNECEFK_00990 1.16e-306 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GKNECEFK_00991 8.12e-196 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GKNECEFK_00992 2.8e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
GKNECEFK_00993 5.37e-106 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
GKNECEFK_00994 4.34e-166 - - - S - - - Peptidase family M23
GKNECEFK_00995 9e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GKNECEFK_00996 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GKNECEFK_00997 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
GKNECEFK_00998 9.03e-229 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
GKNECEFK_00999 4.11e-173 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
GKNECEFK_01000 1.37e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GKNECEFK_01001 3.58e-129 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GKNECEFK_01002 1.74e-224 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
GKNECEFK_01003 1.08e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
GKNECEFK_01004 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
GKNECEFK_01005 6.94e-199 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GKNECEFK_01007 2.28e-19 - - - - - - - -
GKNECEFK_01009 1.87e-21 - - - K - - - Cro/C1-type HTH DNA-binding domain
GKNECEFK_01010 1.74e-17 - - - - - - - -
GKNECEFK_01012 8.82e-97 - - - S - - - Phage antirepressor protein KilAC domain
GKNECEFK_01017 2.18e-07 - - - - - - - -
GKNECEFK_01018 3.08e-125 - - - S - - - AntA/AntB antirepressor
GKNECEFK_01023 3.9e-08 - - - K - - - DNA-binding protein
GKNECEFK_01027 6.82e-72 - - - S - - - Protein of unknown function (DUF1071)
GKNECEFK_01028 1.4e-39 - - - S - - - Conserved phage C-terminus (Phg_2220_C)
GKNECEFK_01029 6.52e-64 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
GKNECEFK_01034 5.99e-52 - - - L - - - Endodeoxyribonuclease RusA
GKNECEFK_01035 1.08e-10 - - - - - - - -
GKNECEFK_01042 1.12e-45 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
GKNECEFK_01043 7.69e-16 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
GKNECEFK_01044 3.6e-47 - - - L ko:K07474 - ko00000 Terminase small subunit
GKNECEFK_01045 4.26e-288 - - - S - - - Terminase-like family
GKNECEFK_01046 7.5e-177 - - - S ko:K09961 - ko00000 Protein of unknown function (DUF1073)
GKNECEFK_01047 3.57e-128 - - - S - - - Phage Mu protein F like protein
GKNECEFK_01048 1.14e-16 - - - S - - - Lysin motif
GKNECEFK_01049 2.77e-137 - - - S ko:K09960 - ko00000 Uncharacterized protein conserved in bacteria (DUF2213)
GKNECEFK_01050 3.08e-76 - - - - - - - -
GKNECEFK_01051 3.18e-182 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2184)
GKNECEFK_01053 7.63e-97 - - - - - - - -
GKNECEFK_01054 6e-58 - - - - - - - -
GKNECEFK_01055 5.61e-69 - - - - - - - -
GKNECEFK_01056 1.12e-193 - - - S - - - Protein of unknown function (DUF3383)
GKNECEFK_01057 1.33e-73 - - - - - - - -
GKNECEFK_01060 0.0 - - - L - - - Phage tail tape measure protein TP901
GKNECEFK_01061 1.06e-69 - - - M - - - LysM domain
GKNECEFK_01062 6.91e-61 - - - - - - - -
GKNECEFK_01063 1.11e-128 - - - - - - - -
GKNECEFK_01064 4.6e-63 - - - - - - - -
GKNECEFK_01065 1.37e-42 - - - - - - - -
GKNECEFK_01066 2.78e-156 - - - S - - - Baseplate J-like protein
GKNECEFK_01068 3.47e-42 - - - - - - - -
GKNECEFK_01073 4.71e-58 - - - - - - - -
GKNECEFK_01074 5.57e-26 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
GKNECEFK_01077 6.31e-27 - - - - - - - -
GKNECEFK_01078 1.24e-38 - - - - - - - -
GKNECEFK_01079 4.35e-220 - - - M - - - Glycosyl hydrolases family 25
GKNECEFK_01080 5.3e-32 - - - - - - - -
GKNECEFK_01081 4.6e-45 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
GKNECEFK_01082 7e-131 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
GKNECEFK_01083 7.65e-65 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
GKNECEFK_01084 3.7e-164 - - - S - - - SLAP domain
GKNECEFK_01085 1.75e-120 - - - - - - - -
GKNECEFK_01087 7.04e-159 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
GKNECEFK_01088 2.07e-203 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
GKNECEFK_01089 1.55e-201 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKNECEFK_01090 1.49e-178 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
GKNECEFK_01091 2.22e-60 hupB2 - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GKNECEFK_01092 2.74e-69 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
GKNECEFK_01093 9.43e-52 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
GKNECEFK_01094 7.04e-218 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
GKNECEFK_01095 0.0 - - - S - - - membrane
GKNECEFK_01096 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GKNECEFK_01097 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GKNECEFK_01098 1.94e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GKNECEFK_01099 9.32e-154 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
GKNECEFK_01100 1e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
GKNECEFK_01101 4.95e-89 yqhL - - P - - - Rhodanese-like protein
GKNECEFK_01102 7.74e-216 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GKNECEFK_01103 2.39e-285 ynbB - - P - - - aluminum resistance
GKNECEFK_01104 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
GKNECEFK_01105 1.75e-89 - - - S - - - Domain of unknown function (DUF1934)
GKNECEFK_01106 2.38e-88 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GKNECEFK_01107 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GKNECEFK_01108 1.97e-312 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKNECEFK_01109 3.24e-104 - - - K - - - acetyltransferase
GKNECEFK_01110 1.69e-61 - - - F - - - AAA domain
GKNECEFK_01111 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GKNECEFK_01112 2.07e-196 msmR - - K - - - AraC-like ligand binding domain
GKNECEFK_01113 8.34e-294 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
GKNECEFK_01114 9.63e-136 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GKNECEFK_01115 1.1e-54 - - - K - - - Helix-turn-helix
GKNECEFK_01116 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
GKNECEFK_01118 1.89e-129 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GKNECEFK_01119 4.21e-148 - - - M - - - Rib/alpha-like repeat
GKNECEFK_01120 1.38e-225 - - - M - - - Rib/alpha-like repeat
GKNECEFK_01121 1.82e-05 - - - - - - - -
GKNECEFK_01122 1.94e-96 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
GKNECEFK_01123 3.74e-125 - - - - - - - -
GKNECEFK_01125 2.16e-163 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GKNECEFK_01126 1.63e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GKNECEFK_01127 3.67e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_01128 1.61e-101 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
GKNECEFK_01129 1.2e-41 - - - - - - - -
GKNECEFK_01130 3.12e-196 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GKNECEFK_01131 5.74e-96 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
GKNECEFK_01132 0.0 - - - - - - - -
GKNECEFK_01133 9.67e-33 - - - S - - - Domain of unknown function DUF1829
GKNECEFK_01135 2.62e-238 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
GKNECEFK_01136 0.0 yhaN - - L - - - AAA domain
GKNECEFK_01137 4.24e-289 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
GKNECEFK_01138 8.43e-73 yheA - - S - - - Belongs to the UPF0342 family
GKNECEFK_01139 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GKNECEFK_01140 1.21e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GKNECEFK_01141 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
GKNECEFK_01142 2.17e-232 - - - - - - - -
GKNECEFK_01143 1.15e-54 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKNECEFK_01144 7.83e-303 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKNECEFK_01147 4.41e-305 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
GKNECEFK_01148 1.18e-13 - - - - - - - -
GKNECEFK_01149 6.39e-32 - - - S - - - transposase or invertase
GKNECEFK_01150 9.6e-309 slpX - - S - - - SLAP domain
GKNECEFK_01151 1.43e-186 - - - K - - - SIS domain
GKNECEFK_01152 3.01e-154 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
GKNECEFK_01153 1.03e-237 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
GKNECEFK_01154 1.93e-266 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKNECEFK_01156 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
GKNECEFK_01158 2.67e-148 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GKNECEFK_01159 1.9e-153 - - - G - - - Antibiotic biosynthesis monooxygenase
GKNECEFK_01160 9.01e-115 - - - G - - - Histidine phosphatase superfamily (branch 1)
GKNECEFK_01161 8.92e-136 - - - G - - - Phosphoglycerate mutase family
GKNECEFK_01162 5.68e-211 - - - D - - - nuclear chromosome segregation
GKNECEFK_01163 2.94e-74 - - - S - - - Protein of unknown function (DUF3290)
GKNECEFK_01164 2.23e-150 yviA - - S - - - Protein of unknown function (DUF421)
GKNECEFK_01165 8.83e-204 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GKNECEFK_01166 1.29e-230 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
GKNECEFK_01167 7.24e-204 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
GKNECEFK_01168 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GKNECEFK_01169 5.26e-259 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
GKNECEFK_01170 1.64e-202 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
GKNECEFK_01171 5.62e-187 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKNECEFK_01172 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
GKNECEFK_01173 2.12e-310 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKNECEFK_01174 1.4e-207 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GKNECEFK_01175 1.89e-205 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
GKNECEFK_01176 1.53e-127 yobS - - K - - - Bacterial regulatory proteins, tetR family
GKNECEFK_01177 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
GKNECEFK_01179 1.66e-32 - - - K - - - Acetyltransferase (GNAT) domain
GKNECEFK_01180 1.2e-220 - - - - - - - -
GKNECEFK_01181 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKNECEFK_01182 1.31e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
GKNECEFK_01183 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
GKNECEFK_01184 1.29e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GKNECEFK_01185 2.16e-136 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GKNECEFK_01186 7.81e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GKNECEFK_01187 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKNECEFK_01188 1.98e-35 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
GKNECEFK_01189 2.53e-139 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
GKNECEFK_01190 1.33e-67 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
GKNECEFK_01191 2.43e-239 - - - S - - - Bacteriocin helveticin-J
GKNECEFK_01192 0.0 - - - M - - - Peptidase family M1 domain
GKNECEFK_01193 2.04e-226 - - - S - - - SLAP domain
GKNECEFK_01194 4.65e-278 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
GKNECEFK_01195 2.59e-313 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
GKNECEFK_01196 1.28e-156 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKNECEFK_01197 1.35e-71 ytpP - - CO - - - Thioredoxin
GKNECEFK_01198 2.23e-235 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
GKNECEFK_01199 9.65e-181 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
GKNECEFK_01200 3.51e-222 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
GKNECEFK_01201 1.31e-81 - - - S - - - Domain of unknown function (DUF956)
GKNECEFK_01202 2.07e-203 - - - K - - - Transcriptional regulator
GKNECEFK_01203 7.06e-111 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
GKNECEFK_01204 1.38e-309 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
GKNECEFK_01205 4.47e-58 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GKNECEFK_01206 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
GKNECEFK_01207 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GKNECEFK_01208 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
GKNECEFK_01209 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GKNECEFK_01210 5.75e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKNECEFK_01211 2.7e-277 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
GKNECEFK_01212 5.26e-36 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
GKNECEFK_01213 1.78e-100 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
GKNECEFK_01214 9.64e-42 - - - - - - - -
GKNECEFK_01217 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GKNECEFK_01218 8.79e-162 - - - S - - - Fic/DOC family
GKNECEFK_01222 1.69e-205 - - - - - - - -
GKNECEFK_01226 1.35e-182 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
GKNECEFK_01233 6.63e-259 - - - - - - - -
GKNECEFK_01236 3.71e-76 yodB - - K - - - Transcriptional regulator, HxlR family
GKNECEFK_01237 5.59e-173 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKNECEFK_01238 5.58e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
GKNECEFK_01239 8.13e-215 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKNECEFK_01240 1.13e-108 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
GKNECEFK_01241 2.95e-283 - - - S - - - SLAP domain
GKNECEFK_01242 6.5e-122 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
GKNECEFK_01243 2.19e-18 - - - - - - - -
GKNECEFK_01244 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKNECEFK_01245 3.52e-163 csrR - - K - - - response regulator
GKNECEFK_01246 2.19e-125 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
GKNECEFK_01247 8.01e-276 ylbM - - S - - - Belongs to the UPF0348 family
GKNECEFK_01248 5.09e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GKNECEFK_01249 1.59e-141 yqeK - - H - - - Hydrolase, HD family
GKNECEFK_01250 2.51e-157 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GKNECEFK_01251 5.03e-256 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
GKNECEFK_01252 6.85e-109 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
GKNECEFK_01253 5.81e-253 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GKNECEFK_01254 1.52e-193 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GKNECEFK_01255 8.69e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GKNECEFK_01256 9.64e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
GKNECEFK_01257 1.07e-93 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GKNECEFK_01258 2.08e-20 - - - K - - - Acetyltransferase (GNAT) domain
GKNECEFK_01259 2.18e-103 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
GKNECEFK_01260 5.03e-297 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKNECEFK_01261 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GKNECEFK_01262 2.55e-223 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
GKNECEFK_01263 1.39e-120 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
GKNECEFK_01264 4.92e-73 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
GKNECEFK_01265 1.22e-157 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GKNECEFK_01266 2.28e-21 - - - S - - - PD-(D/E)XK nuclease family transposase
GKNECEFK_01267 1.18e-89 - - - S - - - PD-(D/E)XK nuclease family transposase
GKNECEFK_01268 4.07e-140 - - - K - - - LysR family
GKNECEFK_01269 0.0 - - - C - - - FMN_bind
GKNECEFK_01270 2.52e-140 - - - K - - - LysR family
GKNECEFK_01271 3.53e-287 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
GKNECEFK_01272 0.0 - - - C - - - FMN_bind
GKNECEFK_01273 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
GKNECEFK_01274 5.56e-72 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GKNECEFK_01275 1.34e-289 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GKNECEFK_01276 6.78e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
GKNECEFK_01277 2.08e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GKNECEFK_01278 1.63e-173 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
GKNECEFK_01279 1.64e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GKNECEFK_01280 4.96e-270 - - - S - - - SLAP domain
GKNECEFK_01281 1.15e-154 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
GKNECEFK_01282 7.18e-187 - - - E - - - GDSL-like Lipase/Acylhydrolase family
GKNECEFK_01283 9.86e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GKNECEFK_01284 4.16e-51 ynzC - - S - - - UPF0291 protein
GKNECEFK_01285 1.3e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
GKNECEFK_01286 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKNECEFK_01287 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKNECEFK_01288 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GKNECEFK_01289 8.61e-296 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
GKNECEFK_01290 1.65e-151 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
GKNECEFK_01291 2.03e-251 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
GKNECEFK_01292 2.21e-180 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
GKNECEFK_01293 1.76e-235 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GKNECEFK_01294 5.86e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
GKNECEFK_01295 1.22e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GKNECEFK_01296 6.38e-178 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GKNECEFK_01297 3.93e-181 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
GKNECEFK_01298 6.38e-254 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
GKNECEFK_01299 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GKNECEFK_01300 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKNECEFK_01301 3.4e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
GKNECEFK_01302 1.19e-259 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
GKNECEFK_01303 3.75e-63 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
GKNECEFK_01304 1.61e-64 ylxQ - - J - - - ribosomal protein
GKNECEFK_01305 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GKNECEFK_01306 1.67e-79 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GKNECEFK_01307 1.64e-198 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GKNECEFK_01308 5.35e-223 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
GKNECEFK_01309 6.02e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GKNECEFK_01310 3.74e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKNECEFK_01311 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
GKNECEFK_01312 6.87e-277 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GKNECEFK_01313 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GKNECEFK_01314 1.09e-226 - - - L - - - Belongs to the 'phage' integrase family
GKNECEFK_01317 1.19e-43 - - - S - - - reductase
GKNECEFK_01318 2.98e-50 - - - S - - - reductase
GKNECEFK_01319 6.32e-41 - - - S - - - reductase
GKNECEFK_01320 1.83e-190 yxeH - - S - - - hydrolase
GKNECEFK_01321 1.14e-230 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKNECEFK_01322 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
GKNECEFK_01323 1.58e-140 yngC - - S - - - SNARE associated Golgi protein
GKNECEFK_01324 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GKNECEFK_01325 3.12e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKNECEFK_01326 0.0 oatA - - I - - - Acyltransferase
GKNECEFK_01327 6.82e-223 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GKNECEFK_01328 1.18e-183 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKNECEFK_01329 3.57e-47 - - - S - - - Lipopolysaccharide assembly protein A domain
GKNECEFK_01330 5.14e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
GKNECEFK_01331 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GKNECEFK_01332 1.25e-38 - - - S - - - Protein of unknown function (DUF2929)
GKNECEFK_01333 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GKNECEFK_01334 7.37e-292 - - - - ko:K18640 - ko00000,ko04812 -
GKNECEFK_01337 0.0 - - - U - - - TraM recognition site of TraD and TraG
GKNECEFK_01338 7.21e-23 - - - L ko:K07450 - ko00000 Helix-turn-helix domain
GKNECEFK_01344 2.78e-161 - - - - - - - -
GKNECEFK_01345 2.76e-290 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 DnaB-like helicase C terminal domain
GKNECEFK_01346 1.15e-108 - - - L - - - Initiator Replication protein
GKNECEFK_01348 7.89e-44 - - - S - - - Protein of unknown function (DUF1002)
GKNECEFK_01350 1.4e-313 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GKNECEFK_01351 4.67e-116 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GKNECEFK_01352 2.09e-180 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
GKNECEFK_01353 8.35e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GKNECEFK_01354 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKNECEFK_01355 1.5e-195 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
GKNECEFK_01356 1e-168 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKNECEFK_01357 2.15e-198 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GKNECEFK_01358 2.4e-118 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
GKNECEFK_01359 7.2e-49 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
GKNECEFK_01360 3.67e-88 - - - P - - - NhaP-type Na H and K H
GKNECEFK_01361 9.85e-49 yozE - - S - - - Belongs to the UPF0346 family
GKNECEFK_01362 8.83e-187 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
GKNECEFK_01363 1.8e-143 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
GKNECEFK_01364 5.13e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GKNECEFK_01365 8.13e-206 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKNECEFK_01366 9.58e-112 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
GKNECEFK_01367 6.08e-161 yagE - - E - - - Amino acid permease
GKNECEFK_01368 8.49e-85 - - - E - - - amino acid
GKNECEFK_01369 5.88e-212 repA - - S - - - Replication initiator protein A
GKNECEFK_01370 1.14e-164 - - - S - - - Fic/DOC family
GKNECEFK_01371 1.79e-74 - - - L - - - Resolvase, N-terminal
GKNECEFK_01372 4.18e-208 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GKNECEFK_01373 1.86e-243 - - - L - - - Transposase and inactivated derivatives, IS30 family
GKNECEFK_01377 4.26e-22 - - - L ko:K07467 - ko00000 Replication initiation factor
GKNECEFK_01378 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKNECEFK_01379 5.23e-97 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
GKNECEFK_01380 1.48e-249 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKNECEFK_01381 1.07e-141 tnpR1 - - L - - - Resolvase, N terminal domain
GKNECEFK_01382 6.91e-92 - - - L - - - IS1381, transposase OrfA
GKNECEFK_01383 4.87e-96 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GKNECEFK_01384 1.17e-38 - - - - - - - -
GKNECEFK_01385 4.65e-184 - - - D - - - AAA domain
GKNECEFK_01386 2.42e-204 - - - L - - - HNH nucleases
GKNECEFK_01387 1.11e-154 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
GKNECEFK_01388 3.67e-225 - - - G - - - Glycosyl hydrolases family 8
GKNECEFK_01389 1.17e-239 - - - M - - - Glycosyl transferase
GKNECEFK_01390 1.34e-09 - - - S - - - Uncharacterised protein family (UPF0236)
GKNECEFK_01391 9.69e-25 - - - - - - - -
GKNECEFK_01392 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
GKNECEFK_01393 3.34e-92 - - - S - - - Iron-sulphur cluster biosynthesis
GKNECEFK_01394 7.23e-244 ysdE - - P - - - Citrate transporter
GKNECEFK_01395 1.43e-125 lemA - - S ko:K03744 - ko00000 LemA family
GKNECEFK_01396 1.16e-207 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
GKNECEFK_01397 1.05e-222 - - - K - - - helix_turn_helix, arabinose operon control protein
GKNECEFK_01398 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_01399 1.19e-114 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GKNECEFK_01400 1.09e-223 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
GKNECEFK_01401 6.67e-115 - - - G - - - Peptidase_C39 like family
GKNECEFK_01402 2.16e-207 - - - M - - - NlpC/P60 family
GKNECEFK_01403 1.93e-32 - - - G - - - Peptidase_C39 like family
GKNECEFK_01404 3.39e-88 - - - S ko:K06915 - ko00000 cog cog0433
GKNECEFK_01405 9.86e-146 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
GKNECEFK_01406 8.81e-40 - - - M - - - Mycoplasma protein of unknown function, DUF285
GKNECEFK_01408 1.61e-70 - - - - - - - -
GKNECEFK_01409 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
GKNECEFK_01410 3.16e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GKNECEFK_01411 2.28e-221 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GKNECEFK_01412 4.13e-255 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GKNECEFK_01413 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
GKNECEFK_01414 0.0 FbpA - - K - - - Fibronectin-binding protein
GKNECEFK_01415 2.06e-88 - - - - - - - -
GKNECEFK_01416 1.15e-204 - - - S - - - EDD domain protein, DegV family
GKNECEFK_01417 3.94e-252 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
GKNECEFK_01418 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
GKNECEFK_01419 4.16e-280 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GKNECEFK_01420 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
GKNECEFK_01421 4.09e-127 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
GKNECEFK_01422 3.77e-260 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
GKNECEFK_01423 6.03e-210 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GKNECEFK_01424 4.06e-277 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
GKNECEFK_01425 2.22e-98 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
GKNECEFK_01426 4.61e-180 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
GKNECEFK_01427 2.84e-240 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GKNECEFK_01428 2.44e-210 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
GKNECEFK_01429 5.55e-137 - - - K - - - Transcriptional regulator, AbiEi antitoxin
GKNECEFK_01430 4.05e-242 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
GKNECEFK_01431 1.89e-23 - - - - - - - -
GKNECEFK_01432 0.0 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
GKNECEFK_01433 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
GKNECEFK_01434 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
GKNECEFK_01435 4.48e-34 - - - - - - - -
GKNECEFK_01436 1.07e-35 - - - - - - - -
GKNECEFK_01437 1.95e-45 - - - - - - - -
GKNECEFK_01438 6.94e-70 - - - S - - - Enterocin A Immunity
GKNECEFK_01439 7.79e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
GKNECEFK_01440 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKNECEFK_01441 9.28e-271 - - - T - - - His Kinase A (phosphoacceptor) domain
GKNECEFK_01442 8.32e-157 vanR - - K - - - response regulator
GKNECEFK_01444 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
GKNECEFK_01445 1.68e-179 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_01446 1.22e-190 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_01447 3.51e-218 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
GKNECEFK_01448 5.61e-138 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
GKNECEFK_01449 5.18e-109 - - - - - - - -
GKNECEFK_01450 0.0 - - - S - - - Calcineurin-like phosphoesterase
GKNECEFK_01451 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GKNECEFK_01452 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
GKNECEFK_01453 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
GKNECEFK_01454 1.35e-180 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GKNECEFK_01455 3.41e-132 yitW - - S - - - Iron-sulfur cluster assembly protein
GKNECEFK_01456 2.19e-292 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
GKNECEFK_01457 2.31e-277 yqjV - - EGP - - - Major Facilitator Superfamily
GKNECEFK_01458 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
GKNECEFK_01464 1.67e-279 - - - - - - - -
GKNECEFK_01465 0.0 - - - U - - - Psort location Cytoplasmic, score
GKNECEFK_01466 0.0 - - - - - - - -
GKNECEFK_01468 1.17e-18 - - - - - - - -
GKNECEFK_01469 6.41e-27 - - - L - - - Addiction module antitoxin, RelB DinJ family
GKNECEFK_01471 8.21e-228 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKNECEFK_01472 1.86e-117 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GKNECEFK_01473 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
GKNECEFK_01474 2.57e-223 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
GKNECEFK_01475 5.31e-206 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GKNECEFK_01476 5.74e-243 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKNECEFK_01477 2.34e-122 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKNECEFK_01478 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GKNECEFK_01479 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GKNECEFK_01480 1.66e-217 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GKNECEFK_01481 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
GKNECEFK_01482 5.26e-171 - - - H - - - Aldolase/RraA
GKNECEFK_01483 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
GKNECEFK_01484 2.56e-196 - - - I - - - Alpha/beta hydrolase family
GKNECEFK_01485 5.17e-249 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GKNECEFK_01486 1.6e-59 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
GKNECEFK_01487 1.79e-214 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
GKNECEFK_01488 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
GKNECEFK_01489 1.24e-93 ytwI - - S - - - Protein of unknown function (DUF441)
GKNECEFK_01490 9.9e-30 - - - - - - - -
GKNECEFK_01491 2.58e-189 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
GKNECEFK_01492 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_01493 5.38e-125 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
GKNECEFK_01494 8.1e-87 - - - S - - - Domain of unknown function DUF1828
GKNECEFK_01495 7.91e-14 - - - - - - - -
GKNECEFK_01496 2.41e-66 - - - - - - - -
GKNECEFK_01497 1.05e-226 citR - - K - - - Putative sugar-binding domain
GKNECEFK_01498 9.28e-317 - - - S - - - Putative threonine/serine exporter
GKNECEFK_01500 5.26e-15 - - - - - - - -
GKNECEFK_01501 1.3e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GKNECEFK_01502 4.8e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
GKNECEFK_01503 3.8e-80 - - - - - - - -
GKNECEFK_01504 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKNECEFK_01505 1.8e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GKNECEFK_01506 7.1e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
GKNECEFK_01507 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GKNECEFK_01508 5.51e-284 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKNECEFK_01509 5.22e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
GKNECEFK_01510 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GKNECEFK_01511 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKNECEFK_01512 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GKNECEFK_01513 4.95e-98 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GKNECEFK_01514 1.56e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKNECEFK_01515 1.55e-122 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
GKNECEFK_01516 1.19e-45 - - - - - - - -
GKNECEFK_01517 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GKNECEFK_01518 1.52e-87 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GKNECEFK_01519 1.34e-310 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GKNECEFK_01520 3.73e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GKNECEFK_01521 1.23e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
GKNECEFK_01522 3.82e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GKNECEFK_01523 1.05e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GKNECEFK_01524 5.48e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GKNECEFK_01525 5.46e-233 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GKNECEFK_01526 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
GKNECEFK_01527 1.21e-213 yitL - - S ko:K00243 - ko00000 S1 domain
GKNECEFK_01528 6.74e-213 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
GKNECEFK_01529 1.13e-81 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKNECEFK_01530 1.81e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GKNECEFK_01531 7.57e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GKNECEFK_01532 4.65e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GKNECEFK_01533 8.49e-146 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GKNECEFK_01534 1.13e-41 - - - M - - - Lysin motif
GKNECEFK_01535 1.96e-148 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
GKNECEFK_01536 1.4e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
GKNECEFK_01537 1.34e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GKNECEFK_01538 8.21e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GKNECEFK_01539 4.33e-95 XK27_05225 - - S - - - Tetratricopeptide repeat protein
GKNECEFK_01540 1.23e-125 XK27_05225 - - S - - - Tetratricopeptide repeat protein
GKNECEFK_01541 2e-299 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKNECEFK_01542 1.76e-234 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
GKNECEFK_01543 6.9e-150 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
GKNECEFK_01544 2.15e-137 - - - S - - - Protein of unknown function (DUF1461)
GKNECEFK_01545 6.38e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GKNECEFK_01546 4.25e-119 yutD - - S - - - Protein of unknown function (DUF1027)
GKNECEFK_01547 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GKNECEFK_01548 9.89e-74 - - - - - - - -
GKNECEFK_01549 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GKNECEFK_01550 2.49e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
GKNECEFK_01551 1.6e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
GKNECEFK_01552 3.09e-71 - - - - - - - -
GKNECEFK_01553 2.96e-23 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GKNECEFK_01554 4.28e-187 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
GKNECEFK_01555 4.52e-126 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GKNECEFK_01556 8.46e-172 - - - - - - - -
GKNECEFK_01557 5.53e-147 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
GKNECEFK_01558 4.16e-70 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
GKNECEFK_01559 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
GKNECEFK_01560 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
GKNECEFK_01561 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
GKNECEFK_01562 9.37e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
GKNECEFK_01563 7e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKNECEFK_01564 2.51e-280 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKNECEFK_01565 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKNECEFK_01566 1.39e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKNECEFK_01567 4.73e-84 - - - K - - - Helix-turn-helix XRE-family like proteins
GKNECEFK_01573 0.0 - - - - - - - -
GKNECEFK_01575 2.77e-82 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GKNECEFK_01577 1.23e-57 - - - - - - - -
GKNECEFK_01578 2.71e-39 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
GKNECEFK_01579 1.62e-105 yveB - - I - - - PAP2 superfamily
GKNECEFK_01580 1.09e-229 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
GKNECEFK_01586 8.79e-163 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GKNECEFK_01589 2.3e-161 - - - - - - - -
GKNECEFK_01590 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
GKNECEFK_01591 5.41e-172 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_01592 2.1e-31 - - - - - - - -
GKNECEFK_01593 1.69e-06 - - - - - - - -
GKNECEFK_01594 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GKNECEFK_01595 4.69e-226 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GKNECEFK_01596 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
GKNECEFK_01597 2.8e-160 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GKNECEFK_01598 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKNECEFK_01599 1e-301 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKNECEFK_01600 1.62e-276 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKNECEFK_01601 9.39e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GKNECEFK_01602 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GKNECEFK_01603 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GKNECEFK_01604 1.07e-52 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
GKNECEFK_01605 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
GKNECEFK_01606 1.64e-200 yhaX - - S - - - Sucrose-6F-phosphate phosphohydrolase
GKNECEFK_01607 0.0 - - - E - - - amino acid
GKNECEFK_01608 1.33e-295 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GKNECEFK_01609 1.17e-56 - - - - - - - -
GKNECEFK_01610 8.68e-69 - - - - - - - -
GKNECEFK_01611 3.44e-238 - - - C - - - FMN-dependent dehydrogenase
GKNECEFK_01612 8.88e-178 - - - P - - - Voltage gated chloride channel
GKNECEFK_01619 3.15e-265 mod 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
GKNECEFK_01620 0.0 XK27_03440 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
GKNECEFK_01625 0.0 - - - V - - - ABC transporter transmembrane region
GKNECEFK_01626 3.53e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
GKNECEFK_01627 2.12e-139 - - - T - - - Transcriptional regulatory protein, C terminal
GKNECEFK_01628 1.38e-229 - - - T - - - GHKL domain
GKNECEFK_01629 1.37e-87 ykoJ - - S - - - Peptidase propeptide and YPEB domain
GKNECEFK_01630 1.89e-77 - - - S - - - Peptidase propeptide and YPEB domain
GKNECEFK_01631 1.09e-107 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
GKNECEFK_01632 5.58e-81 yybA - - K - - - Transcriptional regulator
GKNECEFK_01633 2.18e-76 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
GKNECEFK_01634 1.18e-214 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
GKNECEFK_01635 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKNECEFK_01636 2.56e-81 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
GKNECEFK_01637 8.3e-36 - - - S - - - Peptidase propeptide and YPEB domain
GKNECEFK_01638 2.62e-300 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GKNECEFK_01639 5.5e-155 - - - - - - - -
GKNECEFK_01640 9.18e-202 - - - C - - - Domain of unknown function (DUF4931)
GKNECEFK_01641 3.58e-251 - - - S - - - Putative peptidoglycan binding domain
GKNECEFK_01642 2.61e-23 - - - - - - - -
GKNECEFK_01643 1.05e-119 - - - S - - - membrane
GKNECEFK_01644 5.3e-92 - - - K - - - LytTr DNA-binding domain
GKNECEFK_01645 6.93e-34 - - - S - - - Sugar efflux transporter for intercellular exchange
GKNECEFK_01646 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
GKNECEFK_01647 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
GKNECEFK_01648 2.2e-79 lysM - - M - - - LysM domain
GKNECEFK_01649 7.62e-223 - - - - - - - -
GKNECEFK_01650 6.74e-212 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
GKNECEFK_01651 1.27e-58 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
GKNECEFK_01652 4.76e-168 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
GKNECEFK_01653 3.16e-144 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_01654 0.0 - - - S - - - SH3-like domain
GKNECEFK_01655 1.16e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GKNECEFK_01656 8.59e-221 whiA - - K ko:K09762 - ko00000 May be required for sporulation
GKNECEFK_01657 2.78e-251 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
GKNECEFK_01658 2.44e-211 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
GKNECEFK_01659 1.55e-117 - - - S - - - Short repeat of unknown function (DUF308)
GKNECEFK_01660 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GKNECEFK_01661 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GKNECEFK_01662 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GKNECEFK_01663 3.42e-232 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GKNECEFK_01664 3.31e-239 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
GKNECEFK_01665 4.04e-203 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GKNECEFK_01666 3.54e-230 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GKNECEFK_01667 8.33e-27 - - - - - - - -
GKNECEFK_01668 2.24e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GKNECEFK_01669 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GKNECEFK_01670 1.55e-122 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GKNECEFK_01671 9.44e-169 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
GKNECEFK_01672 2.68e-314 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
GKNECEFK_01673 5.04e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
GKNECEFK_01674 1.94e-268 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
GKNECEFK_01675 3.03e-293 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
GKNECEFK_01676 1.17e-248 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GKNECEFK_01677 3.92e-123 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKNECEFK_01678 1.63e-154 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
GKNECEFK_01679 1.39e-171 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
GKNECEFK_01680 5.49e-301 ymfH - - S - - - Peptidase M16
GKNECEFK_01681 1.2e-283 ymfF - - S - - - Peptidase M16 inactive domain protein
GKNECEFK_01682 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GKNECEFK_01683 3.12e-91 - - - S - - - Protein of unknown function (DUF1149)
GKNECEFK_01684 2.12e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GKNECEFK_01685 2.19e-270 XK27_05220 - - S - - - AI-2E family transporter
GKNECEFK_01686 1.99e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
GKNECEFK_01687 1.01e-255 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
GKNECEFK_01688 5.03e-76 - - - K - - - Helix-turn-helix domain
GKNECEFK_01689 1.17e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GKNECEFK_01690 1.05e-221 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
GKNECEFK_01691 1.11e-234 - - - K - - - Transcriptional regulator
GKNECEFK_01692 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKNECEFK_01693 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKNECEFK_01694 9.39e-141 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GKNECEFK_01695 0.0 snf - - KL - - - domain protein
GKNECEFK_01696 1.19e-188 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
GKNECEFK_01697 7.44e-192 yycI - - S - - - YycH protein
GKNECEFK_01698 0.0 yycH - - S - - - YycH protein
GKNECEFK_01699 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKNECEFK_01700 3.98e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GKNECEFK_01702 1.09e-46 - - - - - - - -
GKNECEFK_01704 4.19e-192 - - - I - - - Acyl-transferase
GKNECEFK_01705 7.23e-201 arbx - - M - - - Glycosyl transferase family 8
GKNECEFK_01706 1.91e-236 - - - M - - - Glycosyl transferase family 8
GKNECEFK_01707 5.48e-235 - - - M - - - Glycosyl transferase family 8
GKNECEFK_01708 3.92e-215 arbZ - - I - - - Phosphate acyltransferases
GKNECEFK_01709 3.37e-50 - - - S - - - Cytochrome B5
GKNECEFK_01710 1.38e-107 - - - J - - - FR47-like protein
GKNECEFK_01711 2.15e-194 - - - L - - - Phage integrase, N-terminal SAM-like domain
GKNECEFK_01712 7.64e-88 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKNECEFK_01713 2.95e-84 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKNECEFK_01714 1.31e-16 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
GKNECEFK_01715 3.03e-145 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GKNECEFK_01716 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
GKNECEFK_01717 9.58e-122 - - - C - - - Pyridoxamine 5'-phosphate oxidase
GKNECEFK_01718 0.0 - - - E - - - Amino acid permease
GKNECEFK_01719 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
GKNECEFK_01720 1.43e-310 ynbB - - P - - - aluminum resistance
GKNECEFK_01721 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
GKNECEFK_01749 1.72e-286 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
GKNECEFK_01750 3.68e-256 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
GKNECEFK_01751 5.35e-224 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKNECEFK_01752 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GKNECEFK_01753 1.3e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
GKNECEFK_01754 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GKNECEFK_01755 1.58e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GKNECEFK_01756 3.93e-176 - - - S - - - Protein of unknown function (DUF1129)
GKNECEFK_01757 6.88e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GKNECEFK_01758 1.1e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
GKNECEFK_01759 4.28e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GKNECEFK_01760 4.99e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
GKNECEFK_01761 5.86e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GKNECEFK_01762 3.66e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
GKNECEFK_01763 2.12e-86 - - - L - - - An automated process has identified a potential problem with this gene model
GKNECEFK_01764 2.24e-36 - - - L - - - An automated process has identified a potential problem with this gene model
GKNECEFK_01765 2.99e-75 cvpA - - S - - - Colicin V production protein
GKNECEFK_01766 5.24e-230 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GKNECEFK_01767 9.48e-194 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GKNECEFK_01768 2.58e-126 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
GKNECEFK_01769 3.41e-125 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
GKNECEFK_01770 1.25e-143 - - - K - - - WHG domain
GKNECEFK_01771 2.63e-50 - - - - - - - -
GKNECEFK_01772 1.38e-165 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKNECEFK_01773 9.06e-184 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKNECEFK_01774 1.44e-53 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKNECEFK_01775 4.98e-37 - - - M - - - LPXTG-motif cell wall anchor domain protein
GKNECEFK_01776 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GKNECEFK_01777 1.23e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GKNECEFK_01778 3.2e-143 - - - S - - - SNARE associated Golgi protein
GKNECEFK_01779 1.77e-194 - - - I - - - alpha/beta hydrolase fold
GKNECEFK_01780 4.69e-201 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
GKNECEFK_01781 1.19e-19 - - - S ko:K07133 - ko00000 cog cog1373
GKNECEFK_01782 1.41e-37 - - - S ko:K07133 - ko00000 cog cog1373
GKNECEFK_01783 2.35e-117 - - - F - - - Nucleoside 2-deoxyribosyltransferase
GKNECEFK_01784 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GKNECEFK_01785 4.61e-70 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
GKNECEFK_01786 1.68e-149 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
GKNECEFK_01787 7.91e-164 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_01788 2.82e-201 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
GKNECEFK_01789 2.9e-254 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKNECEFK_01790 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKNECEFK_01791 7.84e-89 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKNECEFK_01792 8.21e-215 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
GKNECEFK_01793 1.3e-201 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GKNECEFK_01794 1.8e-34 - - - - - - - -
GKNECEFK_01795 0.0 sufI - - Q - - - Multicopper oxidase
GKNECEFK_01796 2.44e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKNECEFK_01797 0.0 potE - - E - - - Amino Acid
GKNECEFK_01798 2.65e-107 - - - S - - - Fic/DOC family
GKNECEFK_01799 1.66e-227 - - - - - - - -
GKNECEFK_01800 8.22e-117 - - - - - - - -
GKNECEFK_01801 5.06e-111 - - - - - - - -
GKNECEFK_01802 3.72e-111 yhaH - - S - - - Protein of unknown function (DUF805)
GKNECEFK_01803 3.91e-91 - - - O - - - OsmC-like protein
GKNECEFK_01804 6.74e-267 - - - EGP - - - Major Facilitator Superfamily
GKNECEFK_01805 2.27e-132 sptS - - T - - - Histidine kinase
GKNECEFK_01806 2.05e-146 sptS - - T - - - Histidine kinase
GKNECEFK_01807 1.52e-135 dltr - - K - - - response regulator
GKNECEFK_01808 1.19e-128 - - - T - - - Region found in RelA / SpoT proteins
GKNECEFK_01809 2e-149 - - - S - - - Peptidase family M23
GKNECEFK_01810 1.22e-136 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GKNECEFK_01812 2.83e-205 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKNECEFK_01813 3.17e-150 - - - - - - - -
GKNECEFK_01814 3.06e-202 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GKNECEFK_01815 2.95e-283 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
GKNECEFK_01816 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
GKNECEFK_01817 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GKNECEFK_01818 6.83e-133 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
GKNECEFK_01821 1.81e-110 - - - L - - - Resolvase, N terminal domain
GKNECEFK_01822 2.54e-247 - - - L - - - Probable transposase
GKNECEFK_01825 4.88e-273 - - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GKNECEFK_01826 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GKNECEFK_01831 2.41e-39 - - - - - - - -
GKNECEFK_01834 4.82e-144 - - - K - - - Helix-turn-helix XRE-family like proteins
GKNECEFK_01835 1.25e-94 - - - K - - - Helix-turn-helix domain
GKNECEFK_01837 6.66e-27 - - - S - - - CAAX protease self-immunity
GKNECEFK_01838 2.67e-35 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
GKNECEFK_01840 4.11e-124 potE - - E - - - thought to be involved in transport amino acids across the membrane
GKNECEFK_01842 2.23e-189 - - - S - - - Putative ABC-transporter type IV
GKNECEFK_01844 5.61e-38 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GKNECEFK_01845 0.0 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GKNECEFK_01846 1.09e-148 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GKNECEFK_01847 3.26e-292 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKNECEFK_01848 4.65e-120 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKNECEFK_01849 8.87e-226 ydbI - - K - - - AI-2E family transporter
GKNECEFK_01850 3.93e-134 - - - E - - - GDSL-like Lipase/Acylhydrolase
GKNECEFK_01851 2.55e-26 - - - - - - - -
GKNECEFK_01852 1.59e-315 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
GKNECEFK_01853 8.64e-176 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_01854 4.76e-168 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GKNECEFK_01855 3.35e-223 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
GKNECEFK_01856 7.75e-170 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GKNECEFK_01857 7.2e-202 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
GKNECEFK_01858 9.52e-205 yvgN - - C - - - Aldo keto reductase
GKNECEFK_01859 0.0 fusA1 - - J - - - elongation factor G
GKNECEFK_01860 3.16e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 haloacid dehalogenase-like hydrolase
GKNECEFK_01861 5.69e-180 - - - EGP - - - Major Facilitator Superfamily
GKNECEFK_01862 9.62e-247 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKNECEFK_01863 1.44e-07 - - - S - - - YSIRK type signal peptide
GKNECEFK_01865 1.2e-202 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GKNECEFK_01866 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
GKNECEFK_01867 0.0 - - - L - - - Helicase C-terminal domain protein
GKNECEFK_01868 6.72e-261 pbpX - - V - - - Beta-lactamase
GKNECEFK_01869 1.05e-289 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
GKNECEFK_01870 4.19e-92 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
GKNECEFK_01872 4.4e-86 - - - K - - - LytTr DNA-binding domain
GKNECEFK_01873 6.11e-66 - - - S - - - Protein of unknown function (DUF3021)
GKNECEFK_01874 4.57e-135 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
GKNECEFK_01875 1.1e-152 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GKNECEFK_01876 2.02e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
GKNECEFK_01877 3.16e-160 - - - G - - - Belongs to the phosphoglycerate mutase family
GKNECEFK_01878 8.43e-206 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
GKNECEFK_01879 2.42e-33 - - - - - - - -
GKNECEFK_01880 9.82e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKNECEFK_01881 2.32e-234 - - - S - - - AAA domain
GKNECEFK_01882 2.13e-66 - - - - - - - -
GKNECEFK_01883 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
GKNECEFK_01884 4.51e-69 - - - - - - - -
GKNECEFK_01885 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
GKNECEFK_01886 3.03e-177 lysR5 - - K - - - LysR substrate binding domain
GKNECEFK_01887 2.06e-298 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
GKNECEFK_01888 5.39e-84 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GKNECEFK_01889 2.01e-135 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
GKNECEFK_01890 1.76e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
GKNECEFK_01891 1.07e-287 - - - S - - - Sterol carrier protein domain
GKNECEFK_01892 4.04e-29 - - - - - - - -
GKNECEFK_01893 6.93e-140 - - - K - - - LysR substrate binding domain
GKNECEFK_01894 1.13e-126 - - - - - - - -
GKNECEFK_01895 5.04e-154 - - - G - - - Antibiotic biosynthesis monooxygenase
GKNECEFK_01896 0.0 - - - V - - - ABC transporter transmembrane region
GKNECEFK_01897 2.27e-179 - - - - - - - -
GKNECEFK_01901 2.23e-48 - - - - - - - -
GKNECEFK_01902 2.52e-76 - - - S - - - Cupredoxin-like domain
GKNECEFK_01903 4.44e-65 - - - S - - - Cupredoxin-like domain
GKNECEFK_01904 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
GKNECEFK_01905 6.63e-147 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
GKNECEFK_01906 7.41e-136 - - - - - - - -
GKNECEFK_01907 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKNECEFK_01908 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKNECEFK_01909 1.77e-157 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GKNECEFK_01910 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
GKNECEFK_01912 9.39e-71 - - - - - - - -
GKNECEFK_01913 7.03e-307 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKNECEFK_01914 0.0 - - - S - - - Fibronectin type III domain
GKNECEFK_01915 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GKNECEFK_01916 5.38e-39 - - - - - - - -
GKNECEFK_01917 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
GKNECEFK_01918 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GKNECEFK_01919 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GKNECEFK_01920 3.37e-192 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKNECEFK_01921 2.65e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GKNECEFK_01922 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
GKNECEFK_01924 2.08e-83 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
GKNECEFK_01925 1.39e-63 - - - L - - - Phage integrase, N-terminal SAM-like domain
GKNECEFK_01932 8.44e-300 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
GKNECEFK_01933 4.36e-93 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
GKNECEFK_01934 2.43e-95 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
GKNECEFK_01935 2.33e-130 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
GKNECEFK_01936 3.87e-15 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN_bind
GKNECEFK_01937 1.63e-109 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
GKNECEFK_01938 1.73e-227 - - - S - - - Conserved hypothetical protein 698
GKNECEFK_01940 1.21e-243 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GKNECEFK_01941 0.0 eriC - - P ko:K03281 - ko00000 chloride
GKNECEFK_01942 1.98e-41 - - - E - - - Zn peptidase
GKNECEFK_01943 8.29e-76 - - - K - - - Helix-turn-helix XRE-family like proteins
GKNECEFK_01944 2.35e-58 - - - - - - - -
GKNECEFK_01945 1.06e-133 - - - S - - - Bacteriocin helveticin-J
GKNECEFK_01946 1.14e-154 - - - S - - - SLAP domain
GKNECEFK_01947 6.57e-175 - - - S - - - SLAP domain
GKNECEFK_01948 1.12e-268 - - - - - - - -
GKNECEFK_01949 6.46e-27 - - - - - - - -
GKNECEFK_01950 2.71e-222 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
GKNECEFK_01951 7.52e-78 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
GKNECEFK_01952 1.61e-81 - - - J ko:K07571 - ko00000 S1 RNA binding domain
GKNECEFK_01953 2.75e-307 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GKNECEFK_01954 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GKNECEFK_01955 3.91e-214 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GKNECEFK_01956 2.77e-248 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKNECEFK_01957 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
GKNECEFK_01958 2.84e-108 - - - K - - - FR47-like protein
GKNECEFK_01959 1.33e-130 - - - M - - - LysM domain protein
GKNECEFK_01960 2.57e-108 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKNECEFK_01961 6.31e-99 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKNECEFK_01962 1.83e-22 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKNECEFK_01963 1.25e-17 - - - - - - - -
GKNECEFK_01964 2.77e-220 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
GKNECEFK_01965 1.04e-41 - - - - - - - -
GKNECEFK_01967 3.65e-90 - - - S - - - Iron-sulphur cluster biosynthesis
GKNECEFK_01968 1.08e-145 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
GKNECEFK_01969 4.51e-77 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
GKNECEFK_01971 6.58e-175 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
GKNECEFK_01972 1.49e-290 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
GKNECEFK_01973 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKNECEFK_01974 7.72e-156 phoB - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
GKNECEFK_01975 6.07e-138 - - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
GKNECEFK_01976 4.66e-179 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKNECEFK_01977 8.63e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
GKNECEFK_01978 8.73e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GKNECEFK_01979 9.14e-187 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GKNECEFK_01980 4.84e-42 - - - - - - - -
GKNECEFK_01981 3.11e-256 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKNECEFK_01982 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GKNECEFK_01983 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
GKNECEFK_01984 1.39e-156 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
GKNECEFK_01985 6.75e-216 - - - K - - - LysR substrate binding domain
GKNECEFK_01986 9.32e-109 - - - S - - - PD-(D/E)XK nuclease family transposase
GKNECEFK_01987 1.41e-51 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
GKNECEFK_01988 3.01e-294 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GKNECEFK_01989 1.03e-206 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
GKNECEFK_01990 1.38e-226 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GKNECEFK_01991 1.76e-165 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GKNECEFK_01992 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GKNECEFK_01993 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GKNECEFK_01994 9.83e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
GKNECEFK_01995 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
GKNECEFK_01996 3.75e-168 - - - K - - - rpiR family
GKNECEFK_01997 7.66e-248 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
GKNECEFK_01998 1.81e-270 - 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKNECEFK_01999 1.32e-151 - - - S - - - Putative esterase
GKNECEFK_02000 3.39e-154 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GKNECEFK_02001 1.92e-102 - - - K - - - Helix-turn-helix domain, rpiR family
GKNECEFK_02003 0.0 mdr - - EGP - - - Major Facilitator
GKNECEFK_02004 7.29e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GKNECEFK_02007 5.31e-211 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GKNECEFK_02012 2.05e-276 - - - M - - - CHAP domain
GKNECEFK_02013 0.0 - - - S - - - regulation of response to stimulus
GKNECEFK_02014 1.09e-279 sgaT - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
GKNECEFK_02015 4.82e-42 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GKNECEFK_02016 2.85e-115 ulaD 4.1.1.85, 4.1.2.43 - G ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
GKNECEFK_02017 1.78e-163 sga 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
GKNECEFK_02018 1.52e-157 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
GKNECEFK_02019 5.85e-86 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
GKNECEFK_02020 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
GKNECEFK_02021 1.01e-22 - - - L - - - Transposase
GKNECEFK_02022 7.51e-16 - - - L - - - Transposase
GKNECEFK_02023 5.14e-105 ykuP - - C ko:K03839 - ko00000 Flavodoxin
GKNECEFK_02024 7.46e-113 gtcA1 - - S - - - Teichoic acid glycosylation protein
GKNECEFK_02025 6.59e-296 - - - L - - - Transposase DDE domain
GKNECEFK_02026 1.62e-278 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GKNECEFK_02028 3.76e-316 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKNECEFK_02029 5.96e-283 yfmL - - L - - - DEAD DEAH box helicase
GKNECEFK_02030 2.16e-79 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GKNECEFK_02031 6.73e-78 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GKNECEFK_02033 4.61e-37 - - - S - - - Enterocin A Immunity
GKNECEFK_02036 1.47e-91 doc - - S ko:K07341 - ko00000,ko02048 Prophage maintenance system killer protein
GKNECEFK_02037 7.27e-42 - - - - - - - -
GKNECEFK_02038 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
GKNECEFK_02039 6.91e-252 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
GKNECEFK_02040 2.33e-143 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
GKNECEFK_02041 7.2e-40 - - - - - - - -
GKNECEFK_02042 5.49e-46 - - - - - - - -
GKNECEFK_02043 8.69e-93 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GKNECEFK_02045 1.14e-115 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
GKNECEFK_02046 7.6e-113 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GKNECEFK_02047 3.56e-191 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
GKNECEFK_02048 3.92e-110 usp5 - - T - - - universal stress protein
GKNECEFK_02050 1.78e-212 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
GKNECEFK_02051 3.67e-179 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GKNECEFK_02052 1.91e-168 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKNECEFK_02053 1.29e-190 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKNECEFK_02054 6.03e-218 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
GKNECEFK_02055 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
GKNECEFK_02056 5.6e-129 - - - M - - - ErfK YbiS YcfS YnhG
GKNECEFK_02057 2.23e-197 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GKNECEFK_02058 9.64e-307 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GKNECEFK_02060 1.59e-61 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
GKNECEFK_02061 1.76e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
GKNECEFK_02062 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKNECEFK_02063 6.53e-291 - - - Q - - - Imidazolonepropionase and related amidohydrolases
GKNECEFK_02064 2.48e-313 - - - S ko:K12941 - ko00000,ko01002 Peptidase dimerisation domain
GKNECEFK_02065 3.2e-176 - - - S - - - Protein of unknown function (DUF3100)
GKNECEFK_02066 2.87e-107 - - - S - - - An automated process has identified a potential problem with this gene model
GKNECEFK_02068 0.0 XK27_00500 - - L - - - the current gene model (or a revised gene model) may contain a
GKNECEFK_02069 3.98e-97 - - - M - - - LysM domain
GKNECEFK_02070 3.3e-42 - - - - - - - -
GKNECEFK_02072 2.58e-45 - - - - - - - -
GKNECEFK_02073 7.84e-95 - - - EGP - - - Major Facilitator
GKNECEFK_02074 9.16e-301 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
GKNECEFK_02075 1.48e-139 - - - EGP - - - Major Facilitator
GKNECEFK_02076 1.24e-169 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
GKNECEFK_02077 1.25e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
GKNECEFK_02078 1.14e-164 terC - - P - - - Integral membrane protein TerC family
GKNECEFK_02079 7.63e-85 yeaO - - S - - - Protein of unknown function, DUF488
GKNECEFK_02080 4.04e-155 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
GKNECEFK_02081 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
GKNECEFK_02082 2.89e-173 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_02083 1.4e-191 yhaH - - S - - - Protein of unknown function (DUF805)
GKNECEFK_02084 1.87e-159 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
GKNECEFK_02085 3.68e-93 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
GKNECEFK_02086 3.02e-171 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GKNECEFK_02087 1.03e-261 - - - M - - - Glycosyl transferases group 1
GKNECEFK_02088 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GKNECEFK_02089 1.91e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GKNECEFK_02090 1.63e-259 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GKNECEFK_02091 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
GKNECEFK_02092 9.16e-287 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GKNECEFK_02093 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
GKNECEFK_02094 5.48e-173 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
GKNECEFK_02095 2.62e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
GKNECEFK_02097 2.26e-118 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
GKNECEFK_02098 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
GKNECEFK_02099 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKNECEFK_02100 6.25e-268 camS - - S - - - sex pheromone
GKNECEFK_02101 5.42e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKNECEFK_02102 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GKNECEFK_02103 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKNECEFK_02104 5.58e-219 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
GKNECEFK_02105 2.61e-148 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
GKNECEFK_02106 1.46e-75 - - - - - - - -
GKNECEFK_02107 9.92e-187 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
GKNECEFK_02108 2.79e-309 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
GKNECEFK_02109 1.01e-256 flp - - V - - - Beta-lactamase
GKNECEFK_02110 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKNECEFK_02111 1.42e-122 - - - K - - - Acetyltransferase (GNAT) domain
GKNECEFK_02116 0.0 qacA - - EGP - - - Major Facilitator
GKNECEFK_02117 1.52e-119 - - - K - - - Bacterial regulatory proteins, tetR family
GKNECEFK_02118 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
GKNECEFK_02119 6.61e-186 - - - S ko:K07133 - ko00000 cog cog1373
GKNECEFK_02120 3.96e-19 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
GKNECEFK_02121 1.92e-42 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
GKNECEFK_02123 6.79e-45 - - - - - - - -
GKNECEFK_02124 3e-271 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
GKNECEFK_02125 1.22e-202 - - - S - - - interspecies interaction between organisms
GKNECEFK_02126 1.28e-09 - - - S - - - PFAM HicB family
GKNECEFK_02127 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
GKNECEFK_02128 9.98e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
GKNECEFK_02129 3.44e-209 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
GKNECEFK_02130 3.22e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GKNECEFK_02131 2.12e-273 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GKNECEFK_02132 4.42e-269 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
GKNECEFK_02133 1.28e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GKNECEFK_02134 8.73e-187 - - - S - - - haloacid dehalogenase-like hydrolase
GKNECEFK_02135 9.01e-287 - - - S ko:K07133 - ko00000 cog cog1373
GKNECEFK_02136 1.92e-80 yneE - - K - - - Transcriptional regulator
GKNECEFK_02137 2.18e-122 yneE - - K - - - Transcriptional regulator
GKNECEFK_02138 3.58e-61 - - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
GKNECEFK_02139 5.05e-11 - - - - - - - -
GKNECEFK_02140 3.69e-54 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
GKNECEFK_02141 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GKNECEFK_02142 1.24e-258 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
GKNECEFK_02143 1.5e-90 - - - - - - - -
GKNECEFK_02144 4.36e-142 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
GKNECEFK_02145 3.35e-269 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
GKNECEFK_02146 2.81e-76 - - - EGP - - - Major Facilitator
GKNECEFK_02147 3.82e-157 rbtT - - P ko:K13021 - ko00000,ko02000 Major Facilitator Superfamily
GKNECEFK_02148 5.25e-258 XK27_00915 - - C - - - Luciferase-like monooxygenase
GKNECEFK_02149 4.36e-28 - - - K - - - GNAT family
GKNECEFK_02150 4.64e-75 - - - K - - - GNAT family
GKNECEFK_02151 3.44e-160 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GKNECEFK_02153 6.04e-49 - - - - - - - -
GKNECEFK_02154 1.23e-166 - - - S - - - (CBS) domain
GKNECEFK_02155 2.93e-234 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GKNECEFK_02156 3.13e-133 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GKNECEFK_02157 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GKNECEFK_02158 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
GKNECEFK_02159 2.12e-132 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKNECEFK_02160 1.05e-233 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
GKNECEFK_02161 1.45e-119 - - - K - - - Bacterial regulatory proteins, tetR family
GKNECEFK_02162 7.88e-143 - - - G - - - phosphoglycerate mutase
GKNECEFK_02163 9.79e-181 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
GKNECEFK_02164 1.45e-183 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
GKNECEFK_02165 1.83e-54 - - - C - - - FMN_bind
GKNECEFK_02166 4.49e-108 - - - - - - - -
GKNECEFK_02167 3.14e-226 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
GKNECEFK_02168 2.06e-111 alkD - - L - - - DNA alkylation repair enzyme
GKNECEFK_02169 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKNECEFK_02170 4.65e-166 - - - K ko:K03492 - ko00000,ko03000 UTRA domain
GKNECEFK_02171 2.19e-73 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
GKNECEFK_02172 7.88e-79 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
GKNECEFK_02173 0.0 - - - E - - - Amino acid permease
GKNECEFK_02174 1.69e-126 - - - L - - - An automated process has identified a potential problem with this gene model
GKNECEFK_02175 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
GKNECEFK_02176 1.15e-121 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKNECEFK_02179 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
GKNECEFK_02180 3.8e-115 - - - M - - - LysM domain protein
GKNECEFK_02181 3.82e-255 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)