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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
AKFMHANA_00001	2.45e-110	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
AKFMHANA_00002	1.26e-55	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
AKFMHANA_00005	8.87e-197	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
AKFMHANA_00006	2.04e-234	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
AKFMHANA_00007	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
AKFMHANA_00008	1.89e-123	-	-	-	-	-	-	-	-
AKFMHANA_00009	1.04e-33	-	-	-	-	-	-	-	-
AKFMHANA_00010	8.08e-83	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
AKFMHANA_00011	7.63e-117	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
AKFMHANA_00013	9.14e-66	-	-	-	-	-	-	-	-
AKFMHANA_00014	2.59e-89	-	-	-	S	-	-	-	Belongs to the HesB IscA family
AKFMHANA_00015	1.81e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
AKFMHANA_00016	2.41e-111	-	-	-	F	-	-	-	NUDIX domain
AKFMHANA_00017	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AKFMHANA_00018	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AKFMHANA_00019	1.9e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AKFMHANA_00020	1.66e-213	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
AKFMHANA_00021	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AKFMHANA_00022	6.71e-208	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
AKFMHANA_00023	9.06e-184	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AKFMHANA_00024	1.46e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AKFMHANA_00025	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
AKFMHANA_00026	2.85e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
AKFMHANA_00027	4.59e-219	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
AKFMHANA_00028	4.49e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
AKFMHANA_00029	2.59e-144	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
AKFMHANA_00030	4.1e-120	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AKFMHANA_00031	1.26e-247	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AKFMHANA_00032	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_00033	2.55e-289	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AKFMHANA_00034	1.16e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
AKFMHANA_00035	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AKFMHANA_00036	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
AKFMHANA_00037	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
AKFMHANA_00038	5.39e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
AKFMHANA_00039	2.15e-83	-	-	-	M	-	-	-	Lysin motif
AKFMHANA_00040	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
AKFMHANA_00041	1.6e-247	-	-	-	S	-	-	-	Helix-turn-helix domain
AKFMHANA_00042	2.65e-133	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AKFMHANA_00043	1.18e-163	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
AKFMHANA_00044	1.57e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AKFMHANA_00045	2.37e-178	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AKFMHANA_00046	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AKFMHANA_00047	4.23e-214	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
AKFMHANA_00048	2.27e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
AKFMHANA_00049	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
AKFMHANA_00050	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
AKFMHANA_00051	7.81e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
AKFMHANA_00052	2.15e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
AKFMHANA_00053	1.25e-199	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AKFMHANA_00054	5.03e-166	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
AKFMHANA_00055	1.24e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
AKFMHANA_00056	3.34e-55	-	-	-	O	-	-	-	Bacterial dnaA protein
AKFMHANA_00057	2.88e-229	-	-	-	-	-	-	-	-
AKFMHANA_00058	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AKFMHANA_00059	2.88e-310	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
AKFMHANA_00060	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
AKFMHANA_00061	2.37e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AKFMHANA_00062	3.24e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
AKFMHANA_00063	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AKFMHANA_00064	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AKFMHANA_00065	1.98e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AKFMHANA_00066	4.5e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AKFMHANA_00067	2.04e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
AKFMHANA_00068	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AKFMHANA_00069	1.18e-273	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AKFMHANA_00070	5.18e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AKFMHANA_00071	6.32e-235	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
AKFMHANA_00072	3.89e-78	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
AKFMHANA_00073	1.42e-126	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AKFMHANA_00074	5.13e-219	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
AKFMHANA_00075	8.37e-231	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
AKFMHANA_00076	3.06e-28	rhaS4	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
AKFMHANA_00077	6.88e-170	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
AKFMHANA_00078	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
AKFMHANA_00079	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
AKFMHANA_00080	3.86e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
AKFMHANA_00081	7.79e-290	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
AKFMHANA_00082	2.62e-122	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AKFMHANA_00083	1.11e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
AKFMHANA_00084	6.66e-151	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AKFMHANA_00085	1.96e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AKFMHANA_00086	2.77e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AKFMHANA_00087	3.19e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AKFMHANA_00088	1.81e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
AKFMHANA_00089	1.56e-20	-	-	-	K	-	-	-	LysR substrate binding domain
AKFMHANA_00090	1.3e-156	-	-	-	K	ko:K09681	-	ko00000,ko03000	DNA-binding transcription factor activity
AKFMHANA_00091	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
AKFMHANA_00092	6.03e-196	-	-	-	E	-	-	-	AzlC protein
AKFMHANA_00093	1.36e-266	hpk31	-	-	T	-	-	-	Histidine kinase
AKFMHANA_00094	9.76e-161	vanR	-	-	K	-	-	-	response regulator
AKFMHANA_00095	1.47e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AKFMHANA_00096	2.28e-220	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
AKFMHANA_00097	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
AKFMHANA_00098	4.23e-305	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
AKFMHANA_00099	9.76e-300	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AKFMHANA_00100	6.58e-152	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AKFMHANA_00101	3.25e-66	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AKFMHANA_00102	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
AKFMHANA_00103	1.7e-200	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
AKFMHANA_00104	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
AKFMHANA_00105	1.54e-191	-	-	-	O	-	-	-	Band 7 protein
AKFMHANA_00106	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
AKFMHANA_00107	2.9e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
AKFMHANA_00108	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
AKFMHANA_00109	6.23e-161	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
AKFMHANA_00110	1.19e-229	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
AKFMHANA_00111	5.79e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
AKFMHANA_00112	4.39e-244	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
AKFMHANA_00113	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
AKFMHANA_00114	8.22e-122	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
AKFMHANA_00115	1.31e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AKFMHANA_00116	4.11e-274	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
AKFMHANA_00117	7.1e-226	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
AKFMHANA_00118	1.09e-221	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
AKFMHANA_00119	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
AKFMHANA_00120	1.15e-115	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
AKFMHANA_00121	5e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
AKFMHANA_00122	2.42e-208	-	-	-	EG	-	-	-	EamA-like transporter family
AKFMHANA_00123	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
AKFMHANA_00124	1.21e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AKFMHANA_00125	1.17e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
AKFMHANA_00126	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AKFMHANA_00127	6.11e-111	-	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
AKFMHANA_00128	1.2e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
AKFMHANA_00129	7.66e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
AKFMHANA_00130	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
AKFMHANA_00131	8.85e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AKFMHANA_00132	7.11e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
AKFMHANA_00133	5.52e-265	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
AKFMHANA_00134	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
AKFMHANA_00135	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
AKFMHANA_00136	5.11e-208	-	-	-	S	-	-	-	EDD domain protein, DegV family
AKFMHANA_00137	7.18e-126	-	-	-	-	-	-	-	-
AKFMHANA_00138	7.48e-155	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
AKFMHANA_00139	9.18e-206	gspA	-	-	M	-	-	-	family 8
AKFMHANA_00140	5.98e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
AKFMHANA_00141	1.11e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
AKFMHANA_00142	6.64e-233	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
AKFMHANA_00143	2.54e-69	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
AKFMHANA_00144	4.52e-45	-	-	-	-	-	-	-	-
AKFMHANA_00149	2.14e-07	-	-	-	N	-	-	-	S-layer homology domain
AKFMHANA_00150	7.38e-40	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
AKFMHANA_00153	0.0	-	-	-	M	-	-	-	CHAP domain
AKFMHANA_00154	4.86e-214	-	-	-	S	-	-	-	Phage tail protein
AKFMHANA_00155	0.0	-	-	-	D	-	-	-	domain protein
AKFMHANA_00156	3.51e-119	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
AKFMHANA_00157	1.15e-152	-	-	-	-	-	-	-	-
AKFMHANA_00158	8.81e-89	-	-	-	-	-	-	-	-
AKFMHANA_00159	5.57e-123	-	-	-	-	-	-	-	-
AKFMHANA_00160	2.19e-67	-	-	-	-	-	-	-	-
AKFMHANA_00161	1.67e-77	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
AKFMHANA_00162	1.23e-255	gpG	-	-	-	-	-	-	-
AKFMHANA_00163	4.76e-137	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
AKFMHANA_00165	1.44e-226	-	-	-	S	-	-	-	Phage Mu protein F like protein
AKFMHANA_00166	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
AKFMHANA_00167	0.0	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
AKFMHANA_00168	5.3e-63	-	-	-	L	-	-	-	transposase activity
AKFMHANA_00169	1.03e-150	-	-	-	K	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
AKFMHANA_00172	2.6e-157	-	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	sulfate reduction
AKFMHANA_00175	1.21e-47	-	-	-	-	-	-	-	-
AKFMHANA_00180	1.77e-100	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
AKFMHANA_00182	7.01e-54	-	-	-	S	-	-	-	ORF6C domain
AKFMHANA_00183	1.22e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
AKFMHANA_00185	8.68e-74	-	-	-	-	-	-	-	-
AKFMHANA_00186	2.09e-59	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
AKFMHANA_00187	1.28e-84	-	-	-	S	-	-	-	Putative HNHc nuclease
AKFMHANA_00188	5.35e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
AKFMHANA_00189	3.27e-158	-	-	-	S	-	-	-	AAA domain
AKFMHANA_00193	1.06e-18	-	-	-	S	ko:K09946	-	ko00000	Domain of unknown function (DUF1508)
AKFMHANA_00199	1.33e-11	-	-	-	-	-	-	-	-
AKFMHANA_00200	8.67e-64	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AKFMHANA_00206	1.64e-301	int	-	-	L	ko:K06400	-	ko00000	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AKFMHANA_00207	2.77e-306	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
AKFMHANA_00208	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
AKFMHANA_00209	6.47e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
AKFMHANA_00210	4.92e-213	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
AKFMHANA_00211	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
AKFMHANA_00212	6.46e-74	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
AKFMHANA_00213	1.94e-305	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
AKFMHANA_00214	1.14e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
AKFMHANA_00215	6.27e-125	-	-	-	P	-	-	-	Cadmium resistance transporter
AKFMHANA_00216	3.96e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_00217	6.8e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
AKFMHANA_00218	7.76e-234	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
AKFMHANA_00219	6.32e-171	-	-	-	M	-	-	-	PFAM NLP P60 protein
AKFMHANA_00221	3.01e-19	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
AKFMHANA_00222	1.15e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
AKFMHANA_00225	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
AKFMHANA_00226	1.57e-190	-	-	-	S	-	-	-	Putative ABC-transporter type IV
AKFMHANA_00227	1.79e-138	-	-	-	NU	-	-	-	mannosyl-glycoprotein
AKFMHANA_00228	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
AKFMHANA_00229	2.81e-297	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
AKFMHANA_00230	5.51e-264	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
AKFMHANA_00231	2.48e-66	-	-	-	-	-	-	-	-
AKFMHANA_00232	3.19e-182	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
AKFMHANA_00234	8.14e-73	-	-	-	-	-	-	-	-
AKFMHANA_00235	2.8e-159	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
AKFMHANA_00237	1.92e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
AKFMHANA_00238	8.15e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
AKFMHANA_00239	3.49e-269	-	-	-	S	-	-	-	associated with various cellular activities
AKFMHANA_00240	2.59e-314	-	-	-	S	-	-	-	Putative metallopeptidase domain
AKFMHANA_00241	4.23e-64	-	-	-	-	-	-	-	-
AKFMHANA_00242	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
AKFMHANA_00243	1.03e-146	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AKFMHANA_00244	2.45e-119	ymdB	-	-	S	-	-	-	Macro domain protein
AKFMHANA_00245	7.66e-255	-	-	-	EGP	-	-	-	Major Facilitator
AKFMHANA_00246	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AKFMHANA_00247	7.74e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
AKFMHANA_00248	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
AKFMHANA_00249	1.51e-117	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
AKFMHANA_00250	1.9e-115	-	-	-	GM	-	-	-	epimerase
AKFMHANA_00251	4.66e-197	-	-	-	V	-	-	-	(ABC) transporter
AKFMHANA_00252	4.1e-308	yhdP	-	-	S	-	-	-	Transporter associated domain
AKFMHANA_00253	1.15e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
AKFMHANA_00254	2.59e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
AKFMHANA_00255	1.07e-245	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
AKFMHANA_00256	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AKFMHANA_00257	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AKFMHANA_00258	4.48e-55	-	-	-	-	-	-	-	-
AKFMHANA_00259	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
AKFMHANA_00260	1.36e-99	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
AKFMHANA_00261	5.13e-46	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
AKFMHANA_00262	2.71e-103	usp5	-	-	T	-	-	-	universal stress protein
AKFMHANA_00263	3.83e-104	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
AKFMHANA_00264	5.61e-292	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AKFMHANA_00265	1.09e-134	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
AKFMHANA_00266	2.92e-233	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
AKFMHANA_00267	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
AKFMHANA_00268	1.08e-289	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AKFMHANA_00269	7.24e-239	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
AKFMHANA_00270	4.87e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
AKFMHANA_00271	1.65e-122	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
AKFMHANA_00272	1.21e-48	-	-	-	-	-	-	-	-
AKFMHANA_00273	4.33e-69	-	-	-	-	-	-	-	-
AKFMHANA_00274	2.72e-262	-	-	-	-	-	-	-	-
AKFMHANA_00275	8.19e-108	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AKFMHANA_00276	5.87e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
AKFMHANA_00277	1.3e-204	yvgN	-	-	S	-	-	-	Aldo keto reductase
AKFMHANA_00278	2.7e-172	XK27_10500	-	-	K	-	-	-	response regulator
AKFMHANA_00279	7.79e-236	-	-	-	T	-	-	-	Histidine kinase-like ATPases
AKFMHANA_00280	5.22e-176	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_00281	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
AKFMHANA_00282	1.78e-204	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
AKFMHANA_00283	2.75e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
AKFMHANA_00284	3.55e-214	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
AKFMHANA_00285	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
AKFMHANA_00286	2.84e-27	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
AKFMHANA_00287	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AKFMHANA_00288	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AKFMHANA_00289	2.61e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
AKFMHANA_00290	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
AKFMHANA_00291	1.91e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AKFMHANA_00292	1.45e-152	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
AKFMHANA_00293	1.59e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
AKFMHANA_00294	3.01e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AKFMHANA_00295	4.29e-162	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
AKFMHANA_00296	8.23e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
AKFMHANA_00297	2.02e-306	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AKFMHANA_00298	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
AKFMHANA_00299	6.72e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AKFMHANA_00300	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AKFMHANA_00301	2.44e-84	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AKFMHANA_00302	6.79e-91	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
AKFMHANA_00303	3.43e-197	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
AKFMHANA_00304	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
AKFMHANA_00305	1.14e-190	yidA	-	-	S	-	-	-	hydrolase
AKFMHANA_00306	2.76e-277	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AKFMHANA_00307	1.43e-247	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
AKFMHANA_00308	3.53e-297	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
AKFMHANA_00309	0.0	tdc	4.1.1.25	-	E	ko:K22330	ko00350,map00350	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
AKFMHANA_00310	1.41e-128	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
AKFMHANA_00311	1.51e-199	-	-	-	J	-	-	-	Methyltransferase
AKFMHANA_00312	1.73e-287	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
AKFMHANA_00313	1.74e-291	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
AKFMHANA_00314	7.81e-46	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
AKFMHANA_00316	0.0	-	-	-	-	-	-	-	-
AKFMHANA_00317	7.75e-164	-	-	-	-	-	-	-	-
AKFMHANA_00318	3.65e-100	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
AKFMHANA_00326	1.12e-49	-	-	-	IQ	-	-	-	dehydrogenase reductase
AKFMHANA_00327	2.64e-244	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
AKFMHANA_00328	1e-61	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
AKFMHANA_00329	0.0	-	-	-	L	-	-	-	PLD-like domain
AKFMHANA_00330	3.62e-92	-	-	-	L	-	-	-	Helix-turn-helix domain
AKFMHANA_00331	4.63e-174	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
AKFMHANA_00332	2.37e-264	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
AKFMHANA_00333	1.12e-131	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
AKFMHANA_00334	5.04e-279	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
AKFMHANA_00335	1.97e-99	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
AKFMHANA_00336	5.65e-19	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
AKFMHANA_00337	7.21e-88	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
AKFMHANA_00338	1.48e-18	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
AKFMHANA_00339	1.18e-72	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AKFMHANA_00340	2.61e-283	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
AKFMHANA_00341	1.34e-05	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
AKFMHANA_00342	2.33e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
AKFMHANA_00344	1.46e-236	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AKFMHANA_00345	9.08e-317	-	-	-	E	ko:K03294	-	ko00000	amino acid
AKFMHANA_00346	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
AKFMHANA_00347	2.99e-289	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
AKFMHANA_00349	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AKFMHANA_00350	2.09e-86	-	-	-	-	-	-	-	-
AKFMHANA_00351	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
AKFMHANA_00352	9.96e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
AKFMHANA_00353	5.75e-117	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
AKFMHANA_00354	2.5e-236	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
AKFMHANA_00355	2.58e-156	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_00356	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_00357	9.71e-50	-	-	-	-	-	-	-	-
AKFMHANA_00358	1.36e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
AKFMHANA_00359	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AKFMHANA_00360	7.96e-223	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
AKFMHANA_00361	2.6e-33	-	-	-	-	-	-	-	-
AKFMHANA_00362	1.03e-146	-	-	-	-	-	-	-	-
AKFMHANA_00363	5.21e-275	yttB	-	-	EGP	-	-	-	Major Facilitator
AKFMHANA_00364	1.61e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
AKFMHANA_00365	1.04e-114	-	-	-	-	-	-	-	-
AKFMHANA_00366	2.13e-142	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
AKFMHANA_00367	1.25e-54	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
AKFMHANA_00368	1.06e-100	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
AKFMHANA_00369	4.34e-200	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AKFMHANA_00370	2.48e-58	-	-	-	-	-	-	-	-
AKFMHANA_00371	3.48e-121	-	-	-	L	-	-	-	PFAM Integrase catalytic region
AKFMHANA_00372	6.12e-71	-	-	-	L	-	-	-	PFAM Integrase catalytic region
AKFMHANA_00373	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
AKFMHANA_00374	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
AKFMHANA_00375	2.13e-122	dpsB	-	-	P	-	-	-	Belongs to the Dps family
AKFMHANA_00376	3.39e-146	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
AKFMHANA_00377	4.84e-21	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
AKFMHANA_00378	4.43e-13	-	-	-	L	-	-	-	Winged helix-turn helix
AKFMHANA_00380	3.62e-268	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
AKFMHANA_00381	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
AKFMHANA_00382	2.89e-110	yvbK	-	-	K	-	-	-	GNAT family
AKFMHANA_00383	5.22e-120	-	-	-	-	-	-	-	-
AKFMHANA_00384	2.24e-160	pnb	-	-	C	-	-	-	nitroreductase
AKFMHANA_00385	5.29e-109	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
AKFMHANA_00386	2.35e-165	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
AKFMHANA_00387	4.43e-100	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
AKFMHANA_00388	1.22e-218	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
AKFMHANA_00389	4.56e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
AKFMHANA_00390	2.57e-103	-	-	-	K	-	-	-	LytTr DNA-binding domain
AKFMHANA_00391	2.44e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
AKFMHANA_00392	7.31e-27	-	-	-	-	-	-	-	-
AKFMHANA_00393	1.59e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
AKFMHANA_00394	3.32e-107	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
AKFMHANA_00395	1.32e-255	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
AKFMHANA_00396	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
AKFMHANA_00397	2.64e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
AKFMHANA_00398	1.66e-142	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
AKFMHANA_00399	7.97e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
AKFMHANA_00400	1.31e-245	mocA	-	-	S	-	-	-	Oxidoreductase
AKFMHANA_00401	2.32e-298	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
AKFMHANA_00403	8.5e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
AKFMHANA_00404	4.96e-73	-	-	-	-	-	-	-	-
AKFMHANA_00406	2.78e-174	-	-	-	M	-	-	-	Prophage endopeptidase tail
AKFMHANA_00407	5.59e-104	-	-	-	S	-	-	-	Phage tail protein
AKFMHANA_00408	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
AKFMHANA_00410	2.92e-13	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
AKFMHANA_00411	1.9e-97	-	-	-	S	-	-	-	Phage tail tube protein
AKFMHANA_00415	8.72e-63	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
AKFMHANA_00416	2.83e-248	-	-	-	S	-	-	-	Phage capsid family
AKFMHANA_00417	3.96e-147	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
AKFMHANA_00418	1.22e-272	-	-	-	S	-	-	-	Phage portal protein
AKFMHANA_00420	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
AKFMHANA_00421	1.49e-85	-	-	-	L	-	-	-	Phage terminase, small subunit
AKFMHANA_00422	1.77e-91	-	-	-	L	-	-	-	HNH nucleases
AKFMHANA_00424	2.08e-11	-	-	-	-	-	-	-	-
AKFMHANA_00428	1.47e-81	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
AKFMHANA_00429	4.17e-30	-	-	-	-	-	-	-	-
AKFMHANA_00431	1.65e-46	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
AKFMHANA_00432	2.5e-99	-	-	-	L	-	-	-	DnaD domain protein
AKFMHANA_00436	1.25e-10	-	-	-	-	-	-	-	-
AKFMHANA_00437	1.14e-82	-	-	-	S	-	-	-	DNA binding
AKFMHANA_00439	9.3e-35	-	-	-	-	-	-	-	-
AKFMHANA_00440	6.11e-19	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AKFMHANA_00441	7.5e-08	-	-	-	E	-	-	-	Pfam:DUF955
AKFMHANA_00442	3.01e-42	-	-	-	-	-	-	-	-
AKFMHANA_00446	3.03e-13	-	-	-	M	-	-	-	LysM domain
AKFMHANA_00447	9.97e-73	-	-	-	S	-	-	-	AAA ATPase domain
AKFMHANA_00448	7.15e-121	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
AKFMHANA_00449	2.26e-65	-	-	-	-	-	-	-	-
AKFMHANA_00450	1.51e-94	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
AKFMHANA_00451	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AKFMHANA_00452	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
AKFMHANA_00453	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
AKFMHANA_00454	1.86e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AKFMHANA_00455	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
AKFMHANA_00456	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
AKFMHANA_00457	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AKFMHANA_00458	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AKFMHANA_00459	4.22e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AKFMHANA_00460	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
AKFMHANA_00461	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AKFMHANA_00462	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AKFMHANA_00463	1.41e-242	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AKFMHANA_00464	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AKFMHANA_00465	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
AKFMHANA_00466	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
AKFMHANA_00467	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
AKFMHANA_00468	6.95e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
AKFMHANA_00469	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
AKFMHANA_00470	1.59e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AKFMHANA_00471	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
AKFMHANA_00472	5.19e-169	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
AKFMHANA_00473	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AKFMHANA_00474	1.81e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AKFMHANA_00475	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AKFMHANA_00476	1.14e-275	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AKFMHANA_00477	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AKFMHANA_00478	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
AKFMHANA_00479	9e-72	-	-	-	-	-	-	-	-
AKFMHANA_00480	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
AKFMHANA_00481	6.71e-102	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
AKFMHANA_00482	1.69e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
AKFMHANA_00483	3.59e-207	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
AKFMHANA_00484	9.86e-59	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AKFMHANA_00485	2.05e-282	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AKFMHANA_00486	2.71e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AKFMHANA_00487	1.06e-90	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AKFMHANA_00488	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
AKFMHANA_00489	6.38e-159	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
AKFMHANA_00490	3.85e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
AKFMHANA_00491	5.46e-170	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AKFMHANA_00492	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
AKFMHANA_00493	8.76e-73	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
AKFMHANA_00494	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
AKFMHANA_00495	1.99e-146	-	-	-	K	-	-	-	Transcriptional regulator
AKFMHANA_00498	3.61e-117	-	-	-	S	-	-	-	Protein conserved in bacteria
AKFMHANA_00499	6.94e-238	-	-	-	-	-	-	-	-
AKFMHANA_00500	8.42e-204	-	-	-	-	-	-	-	-
AKFMHANA_00501	7.62e-68	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
AKFMHANA_00502	6.94e-132	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AKFMHANA_00503	1.51e-200	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
AKFMHANA_00504	1.28e-18	-	-	-	-	-	-	-	-
AKFMHANA_00505	1.31e-286	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
AKFMHANA_00506	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AKFMHANA_00507	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
AKFMHANA_00508	1.06e-228	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AKFMHANA_00509	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
AKFMHANA_00510	2.67e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
AKFMHANA_00511	2.51e-235	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
AKFMHANA_00512	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
AKFMHANA_00513	2.39e-147	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
AKFMHANA_00514	1.38e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AKFMHANA_00515	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
AKFMHANA_00516	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
AKFMHANA_00517	0.0	-	-	-	S	-	-	-	membrane
AKFMHANA_00518	4.64e-92	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
AKFMHANA_00519	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AKFMHANA_00520	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
AKFMHANA_00521	6.17e-151	-	-	-	M	-	-	-	PFAM NLP P60 protein
AKFMHANA_00522	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AKFMHANA_00523	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AKFMHANA_00524	4.77e-77	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
AKFMHANA_00525	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
AKFMHANA_00526	9.44e-187	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKFMHANA_00527	1.07e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
AKFMHANA_00528	9.55e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AKFMHANA_00529	5.74e-94	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
AKFMHANA_00530	1.84e-298	-	-	-	V	-	-	-	MatE
AKFMHANA_00531	0.0	potE	-	-	E	-	-	-	Amino Acid
AKFMHANA_00532	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
AKFMHANA_00533	1.38e-155	csrR	-	-	K	-	-	-	response regulator
AKFMHANA_00534	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
AKFMHANA_00535	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
AKFMHANA_00536	1.75e-276	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
AKFMHANA_00537	9.84e-183	yqeM	-	-	Q	-	-	-	Methyltransferase
AKFMHANA_00538	2.3e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AKFMHANA_00539	6.21e-147	yqeK	-	-	H	-	-	-	Hydrolase, HD family
AKFMHANA_00540	4.36e-161	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AKFMHANA_00541	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
AKFMHANA_00542	1.9e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
AKFMHANA_00543	1.91e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
AKFMHANA_00544	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AKFMHANA_00545	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
AKFMHANA_00546	2.15e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AKFMHANA_00547	7.37e-223	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
AKFMHANA_00548	2.83e-299	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
AKFMHANA_00549	2.32e-104	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AKFMHANA_00550	5.5e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AKFMHANA_00551	3.89e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AKFMHANA_00552	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AKFMHANA_00553	5.87e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
AKFMHANA_00554	4.56e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
AKFMHANA_00555	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
AKFMHANA_00556	3.43e-154	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AKFMHANA_00557	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
AKFMHANA_00558	2.27e-75	-	-	-	S	-	-	-	Small secreted protein
AKFMHANA_00559	6.25e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
AKFMHANA_00560	5.08e-237	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
AKFMHANA_00561	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
AKFMHANA_00562	2.67e-42	-	-	-	A	ko:K12092	ko05120,map05120	ko00000,ko00001,ko00002,ko02044	chlorophyll binding
AKFMHANA_00563	3.3e-174	-	-	-	S	-	-	-	YSIRK type signal peptide
AKFMHANA_00564	2.82e-34	-	-	-	S	-	-	-	YSIRK type signal peptide
AKFMHANA_00565	9.15e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AKFMHANA_00566	3.44e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
AKFMHANA_00567	1.39e-177	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_00568	1.49e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
AKFMHANA_00570	1e-176	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AKFMHANA_00571	0.0	yhaN	-	-	L	-	-	-	AAA domain
AKFMHANA_00572	3.37e-294	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
AKFMHANA_00573	6.48e-78	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
AKFMHANA_00574	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
AKFMHANA_00575	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
AKFMHANA_00576	1.51e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
AKFMHANA_00577	4.93e-216	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
AKFMHANA_00579	1.49e-54	-	-	-	-	-	-	-	-
AKFMHANA_00580	4.61e-61	-	-	-	-	-	-	-	-
AKFMHANA_00581	5.66e-278	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
AKFMHANA_00582	8.88e-138	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
AKFMHANA_00583	5.72e-301	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
AKFMHANA_00584	1.17e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
AKFMHANA_00585	4.05e-124	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
AKFMHANA_00586	1.22e-74	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AKFMHANA_00587	2.21e-155	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
AKFMHANA_00588	1.52e-43	-	-	-	-	-	-	-	-
AKFMHANA_00589	8.45e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AKFMHANA_00590	3.07e-239	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
AKFMHANA_00591	5.33e-147	-	-	-	-	-	-	-	-
AKFMHANA_00592	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
AKFMHANA_00593	4.93e-216	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AKFMHANA_00594	7.5e-13	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AKFMHANA_00595	5.35e-113	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
AKFMHANA_00596	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
AKFMHANA_00597	9.07e-199	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AKFMHANA_00598	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
AKFMHANA_00599	8.74e-57	-	-	-	-	-	-	-	-
AKFMHANA_00600	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
AKFMHANA_00601	6.66e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AKFMHANA_00602	4.49e-130	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
AKFMHANA_00603	7.96e-41	-	-	-	-	-	-	-	-
AKFMHANA_00604	0.0	-	-	-	EGP	-	-	-	Major Facilitator
AKFMHANA_00605	1.25e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
AKFMHANA_00606	8.53e-304	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
AKFMHANA_00607	2.01e-134	-	-	-	V	-	-	-	VanZ like family
AKFMHANA_00608	7.03e-33	-	-	-	-	-	-	-	-
AKFMHANA_00609	2.05e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
AKFMHANA_00610	7.91e-104	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
AKFMHANA_00611	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
AKFMHANA_00612	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
AKFMHANA_00613	2.42e-201	yeaE	-	-	S	-	-	-	Aldo keto
AKFMHANA_00614	2.29e-309	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
AKFMHANA_00615	4.87e-299	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
AKFMHANA_00616	2.83e-190	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
AKFMHANA_00618	5.36e-97	-	-	-	-	-	-	-	-
AKFMHANA_00619	1.73e-288	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
AKFMHANA_00620	1.95e-178	-	-	-	V	-	-	-	Beta-lactamase enzyme family
AKFMHANA_00621	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
AKFMHANA_00622	1.05e-273	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
AKFMHANA_00623	0.0	arcT	-	-	E	-	-	-	Dipeptidase
AKFMHANA_00624	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
AKFMHANA_00625	1.56e-229	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
AKFMHANA_00626	1.26e-64	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
AKFMHANA_00627	2.08e-50	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
AKFMHANA_00628	1.03e-209	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
AKFMHANA_00629	6.66e-177	-	-	-	I	-	-	-	alpha/beta hydrolase fold
AKFMHANA_00630	1.67e-229	-	-	-	S	-	-	-	Conserved hypothetical protein 698
AKFMHANA_00631	1.44e-121	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
AKFMHANA_00632	1.13e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
AKFMHANA_00633	1.1e-227	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
AKFMHANA_00634	5.41e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
AKFMHANA_00635	3.1e-113	-	-	-	Q	-	-	-	Methyltransferase
AKFMHANA_00636	2.68e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
AKFMHANA_00637	4.98e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
AKFMHANA_00638	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
AKFMHANA_00639	6.61e-180	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
AKFMHANA_00640	1.85e-288	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
AKFMHANA_00641	9.03e-313	-	-	-	M	-	-	-	Glycosyl transferase
AKFMHANA_00642	6.17e-202	-	-	-	-	-	-	-	-
AKFMHANA_00643	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AKFMHANA_00644	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AKFMHANA_00645	1.91e-301	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
AKFMHANA_00646	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AKFMHANA_00647	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
AKFMHANA_00648	2.29e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AKFMHANA_00649	2.28e-271	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AKFMHANA_00650	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
AKFMHANA_00651	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
AKFMHANA_00652	9.6e-310	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
AKFMHANA_00653	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
AKFMHANA_00654	8.08e-147	-	-	-	S	-	-	-	(CBS) domain
AKFMHANA_00655	1.38e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AKFMHANA_00656	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AKFMHANA_00657	4.11e-52	yabO	-	-	J	-	-	-	S4 domain protein
AKFMHANA_00658	4.31e-76	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
AKFMHANA_00659	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
AKFMHANA_00660	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AKFMHANA_00661	5.23e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
AKFMHANA_00662	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AKFMHANA_00663	2.77e-219	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AKFMHANA_00664	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AKFMHANA_00665	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
AKFMHANA_00666	6.85e-115	-	-	-	-	-	-	-	-
AKFMHANA_00667	5.87e-147	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
AKFMHANA_00668	3.31e-206	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
AKFMHANA_00669	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
AKFMHANA_00670	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
AKFMHANA_00671	5.28e-105	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
AKFMHANA_00672	3.86e-300	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AKFMHANA_00673	4.96e-307	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
AKFMHANA_00674	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
AKFMHANA_00675	9.89e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
AKFMHANA_00676	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
AKFMHANA_00677	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
AKFMHANA_00678	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AKFMHANA_00679	9.18e-83	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
AKFMHANA_00680	3.51e-142	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
AKFMHANA_00681	5.93e-263	-	-	-	G	-	-	-	Transporter, major facilitator family protein
AKFMHANA_00682	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
AKFMHANA_00683	1.81e-146	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
AKFMHANA_00684	4.12e-227	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
AKFMHANA_00686	0.0	-	-	-	L	-	-	-	PLD-like domain
AKFMHANA_00687	1.27e-82	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
AKFMHANA_00688	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AKFMHANA_00689	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
AKFMHANA_00690	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
AKFMHANA_00691	1.54e-33	-	-	-	-	-	-	-	-
AKFMHANA_00692	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AKFMHANA_00693	2.22e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
AKFMHANA_00694	5.58e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
AKFMHANA_00695	4.35e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AKFMHANA_00696	1.99e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
AKFMHANA_00697	4.96e-51	-	-	-	S	-	-	-	repeat protein
AKFMHANA_00698	4.99e-73	-	-	-	S	-	-	-	repeat protein
AKFMHANA_00699	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AKFMHANA_00700	1.04e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AKFMHANA_00701	1.53e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AKFMHANA_00702	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
AKFMHANA_00703	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AKFMHANA_00704	1.2e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AKFMHANA_00705	4.19e-286	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AKFMHANA_00706	5.62e-224	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AKFMHANA_00707	1.62e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AKFMHANA_00708	1.84e-282	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
AKFMHANA_00709	1.56e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AKFMHANA_00710	5.53e-05	cdaR_3	-	-	QT	ko:K02647	-	ko00000,ko03000	PucR C-terminal helix-turn-helix domain
AKFMHANA_00711	5.59e-54	-	-	-	H	-	-	-	RibD C-terminal domain
AKFMHANA_00712	1.15e-26	-	-	-	S	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
AKFMHANA_00713	3.43e-27	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
AKFMHANA_00714	6.53e-118	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
AKFMHANA_00715	9.8e-75	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
AKFMHANA_00716	5.85e-254	flp	-	-	V	-	-	-	Beta-lactamase
AKFMHANA_00717	2.6e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
AKFMHANA_00718	2.81e-158	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
AKFMHANA_00719	4.91e-156	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
AKFMHANA_00721	3.18e-160	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
AKFMHANA_00722	1.52e-64	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
AKFMHANA_00723	4.61e-155	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
AKFMHANA_00724	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
AKFMHANA_00725	0.0	-	-	-	S	-	-	-	amidohydrolase
AKFMHANA_00726	1.86e-212	-	-	-	S	-	-	-	reductase
AKFMHANA_00727	2.55e-120	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
AKFMHANA_00728	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
AKFMHANA_00729	1.81e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
AKFMHANA_00730	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AKFMHANA_00731	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
AKFMHANA_00732	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AKFMHANA_00733	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AKFMHANA_00734	1.76e-45	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
AKFMHANA_00735	9.54e-241	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AKFMHANA_00736	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_00737	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
AKFMHANA_00738	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
AKFMHANA_00739	4.73e-113	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AKFMHANA_00740	6.1e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
AKFMHANA_00741	2.53e-83	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
AKFMHANA_00742	2.44e-36	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
AKFMHANA_00743	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
AKFMHANA_00744	3.37e-307	-	-	-	E	-	-	-	amino acid
AKFMHANA_00745	1.76e-177	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
AKFMHANA_00746	6.87e-311	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
AKFMHANA_00747	5.98e-211	-	-	-	GK	-	-	-	ROK family
AKFMHANA_00748	0.0	fusA1	-	-	J	-	-	-	elongation factor G
AKFMHANA_00749	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
AKFMHANA_00750	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
AKFMHANA_00751	1.78e-83	-	-	-	-	-	-	-	-
AKFMHANA_00752	3.18e-11	-	-	-	-	-	-	-	-
AKFMHANA_00753	1.41e-152	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
AKFMHANA_00754	7.55e-174	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
AKFMHANA_00756	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AKFMHANA_00757	3.29e-183	-	-	-	M	-	-	-	Glycosyl transferase family 2
AKFMHANA_00758	3e-111	-	-	-	-	-	-	-	-
AKFMHANA_00759	1.6e-36	-	-	-	-	-	-	-	-
AKFMHANA_00761	1.39e-142	-	-	-	-	-	-	-	-
AKFMHANA_00762	1.36e-83	cps3I	-	-	G	-	-	-	Acyltransferase family
AKFMHANA_00763	1.37e-95	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
AKFMHANA_00764	9.95e-58	-	-	-	M	-	-	-	biosynthesis protein
AKFMHANA_00765	4.63e-119	cps3F	-	-	-	-	-	-	-
AKFMHANA_00766	1.58e-124	-	-	-	M	-	-	-	Glycosyltransferase like family 2
AKFMHANA_00767	2.56e-140	-	-	-	S	-	-	-	Glycosyltransferase like family 2
AKFMHANA_00768	1.22e-93	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
AKFMHANA_00769	8.02e-271	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
AKFMHANA_00770	4.3e-279	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
AKFMHANA_00771	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
AKFMHANA_00773	6.68e-238	-	-	-	-	-	-	-	-
AKFMHANA_00774	9.45e-126	-	-	-	K	-	-	-	acetyltransferase
AKFMHANA_00775	5.67e-178	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
AKFMHANA_00776	1.93e-210	-	-	-	K	-	-	-	LysR substrate binding domain
AKFMHANA_00777	1.11e-263	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
AKFMHANA_00778	5.53e-52	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AKFMHANA_00779	2.96e-225	-	-	-	-	-	-	-	-
AKFMHANA_00780	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AKFMHANA_00781	1.26e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
AKFMHANA_00783	2.51e-201	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
AKFMHANA_00784	3.82e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AKFMHANA_00785	1.1e-161	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
AKFMHANA_00786	2.26e-149	-	-	-	S	-	-	-	Membrane
AKFMHANA_00787	3.39e-254	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
AKFMHANA_00788	1.26e-113	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
AKFMHANA_00789	3.7e-19	-	-	-	-	-	-	-	-
AKFMHANA_00790	3.69e-259	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
AKFMHANA_00791	7.98e-114	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
AKFMHANA_00792	2.42e-122	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
AKFMHANA_00793	5.69e-105	-	-	-	-	-	-	-	-
AKFMHANA_00794	6.75e-164	-	-	-	M	-	-	-	Lysin motif
AKFMHANA_00795	3.92e-163	-	-	-	EGP	-	-	-	Major Facilitator
AKFMHANA_00796	4.63e-70	-	-	-	EGP	-	-	-	Major Facilitator
AKFMHANA_00797	1.25e-159	-	-	-	L	-	-	-	PFAM Integrase catalytic region
AKFMHANA_00798	6.13e-100	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
AKFMHANA_00799	6.9e-134	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
AKFMHANA_00800	1.37e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
AKFMHANA_00801	2.26e-214	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AKFMHANA_00802	2.47e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
AKFMHANA_00803	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
AKFMHANA_00804	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AKFMHANA_00805	1.99e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
AKFMHANA_00806	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AKFMHANA_00807	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AKFMHANA_00808	5.17e-70	-	-	-	-	-	-	-	-
AKFMHANA_00809	0.0	oatA	-	-	I	-	-	-	Acyltransferase
AKFMHANA_00810	7.53e-104	-	-	-	K	-	-	-	Transcriptional regulator
AKFMHANA_00811	4.88e-194	-	-	-	S	-	-	-	Cof-like hydrolase
AKFMHANA_00812	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
AKFMHANA_00814	2.06e-176	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
AKFMHANA_00815	0.0	yclK	-	-	T	-	-	-	Histidine kinase
AKFMHANA_00816	7.78e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
AKFMHANA_00817	2.09e-154	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
AKFMHANA_00818	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
AKFMHANA_00819	2.69e-36	-	-	-	-	-	-	-	-
AKFMHANA_00821	6.11e-44	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
AKFMHANA_00822	1.29e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
AKFMHANA_00823	7.15e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
AKFMHANA_00824	1.44e-180	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AKFMHANA_00825	3.03e-129	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
AKFMHANA_00826	6.01e-153	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
AKFMHANA_00827	1.36e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AKFMHANA_00828	5.09e-186	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
AKFMHANA_00830	1.01e-95	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
AKFMHANA_00831	3.65e-60	-	-	-	-	-	-	-	-
AKFMHANA_00832	3.65e-103	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
AKFMHANA_00833	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
AKFMHANA_00834	2.95e-240	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
AKFMHANA_00835	8.77e-237	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
AKFMHANA_00836	1.22e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
AKFMHANA_00837	5.96e-181	-	-	-	-	-	-	-	-
AKFMHANA_00838	1.7e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
AKFMHANA_00839	6.25e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
AKFMHANA_00840	2.93e-58	-	-	-	-	-	-	-	-
AKFMHANA_00841	1.54e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AKFMHANA_00842	1.6e-190	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
AKFMHANA_00843	1.4e-198	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
AKFMHANA_00844	1.79e-100	ykuL	-	-	S	-	-	-	(CBS) domain
AKFMHANA_00845	1.16e-124	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
AKFMHANA_00846	5.35e-139	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AKFMHANA_00847	3.41e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
AKFMHANA_00848	3.01e-126	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
AKFMHANA_00849	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
AKFMHANA_00850	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AKFMHANA_00851	7.15e-122	cvpA	-	-	S	-	-	-	Colicin V production protein
AKFMHANA_00852	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
AKFMHANA_00853	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AKFMHANA_00854	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
AKFMHANA_00855	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AKFMHANA_00856	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AKFMHANA_00857	2.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
AKFMHANA_00858	1.86e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
AKFMHANA_00859	1.11e-260	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AKFMHANA_00860	9.97e-245	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AKFMHANA_00861	4.52e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AKFMHANA_00862	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AKFMHANA_00863	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AKFMHANA_00864	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
AKFMHANA_00865	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AKFMHANA_00866	1.28e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
AKFMHANA_00867	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AKFMHANA_00868	1.45e-197	-	-	-	S	-	-	-	Helix-turn-helix domain
AKFMHANA_00869	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
AKFMHANA_00870	3.68e-295	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
AKFMHANA_00871	2.84e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
AKFMHANA_00872	1.45e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_00873	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
AKFMHANA_00874	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
AKFMHANA_00875	7.72e-195	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
AKFMHANA_00876	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
AKFMHANA_00877	5.97e-157	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
AKFMHANA_00878	1.9e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
AKFMHANA_00879	1.09e-295	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
AKFMHANA_00880	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AKFMHANA_00881	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
AKFMHANA_00882	2.07e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
AKFMHANA_00883	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
AKFMHANA_00884	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AKFMHANA_00885	4.1e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AKFMHANA_00886	2.59e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
AKFMHANA_00887	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AKFMHANA_00888	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AKFMHANA_00889	9.36e-42	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
AKFMHANA_00890	2.58e-253	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
AKFMHANA_00891	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AKFMHANA_00892	2.37e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
AKFMHANA_00893	3.83e-61	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
AKFMHANA_00894	2.75e-286	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
AKFMHANA_00895	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
AKFMHANA_00896	2.12e-178	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
AKFMHANA_00897	2.87e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
AKFMHANA_00898	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
AKFMHANA_00899	1.34e-314	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AKFMHANA_00900	2.31e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
AKFMHANA_00901	2.44e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
AKFMHANA_00902	8.3e-134	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AKFMHANA_00903	2.79e-107	-	-	-	-	-	-	-	-
AKFMHANA_00904	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
AKFMHANA_00905	2.71e-235	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
AKFMHANA_00906	4.37e-39	-	-	-	-	-	-	-	-
AKFMHANA_00907	1.94e-249	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
AKFMHANA_00909	5.28e-76	-	-	-	-	-	-	-	-
AKFMHANA_00910	1.73e-270	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
AKFMHANA_00911	2.31e-281	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
AKFMHANA_00912	2.91e-53	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
AKFMHANA_00913	1.19e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
AKFMHANA_00914	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
AKFMHANA_00915	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
AKFMHANA_00916	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AKFMHANA_00917	7.63e-217	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AKFMHANA_00918	6.56e-252	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AKFMHANA_00919	9.39e-296	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AKFMHANA_00920	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AKFMHANA_00921	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AKFMHANA_00922	4.24e-249	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
AKFMHANA_00923	4.22e-169	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
AKFMHANA_00924	5.64e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
AKFMHANA_00925	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
AKFMHANA_00926	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AKFMHANA_00927	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AKFMHANA_00928	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AKFMHANA_00929	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AKFMHANA_00930	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AKFMHANA_00931	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AKFMHANA_00932	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
AKFMHANA_00933	6.45e-155	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
AKFMHANA_00934	6.57e-163	-	-	-	L	-	-	-	Helix-turn-helix domain
AKFMHANA_00935	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
AKFMHANA_00936	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
AKFMHANA_00937	7.22e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AKFMHANA_00938	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AKFMHANA_00939	7.65e-184	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AKFMHANA_00940	1.21e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AKFMHANA_00941	4.84e-293	-	-	-	-	-	-	-	-
AKFMHANA_00942	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
AKFMHANA_00943	1.46e-96	-	-	-	F	-	-	-	Nudix hydrolase
AKFMHANA_00944	1.87e-132	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
AKFMHANA_00945	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
AKFMHANA_00946	8.66e-37	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
AKFMHANA_00947	8.05e-194	-	-	-	-	-	-	-	-
AKFMHANA_00948	5.87e-51	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
AKFMHANA_00949	1.76e-122	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
AKFMHANA_00950	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
AKFMHANA_00951	9.13e-232	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AKFMHANA_00952	4.08e-106	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
AKFMHANA_00953	6.15e-189	ylmH	-	-	S	-	-	-	S4 domain protein
AKFMHANA_00954	1.11e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
AKFMHANA_00955	1.57e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
AKFMHANA_00956	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AKFMHANA_00957	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AKFMHANA_00958	6.38e-197	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AKFMHANA_00959	2.16e-262	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AKFMHANA_00960	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AKFMHANA_00961	5.44e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AKFMHANA_00962	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
AKFMHANA_00963	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
AKFMHANA_00964	4.61e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AKFMHANA_00965	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
AKFMHANA_00967	1.6e-77	-	-	-	-	-	-	-	-
AKFMHANA_00968	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
AKFMHANA_00969	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
AKFMHANA_00970	2.64e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AKFMHANA_00971	3.61e-209	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
AKFMHANA_00972	2.79e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
AKFMHANA_00973	1.36e-212	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
AKFMHANA_00974	1.56e-80	-	-	-	-	-	-	-	-
AKFMHANA_00975	3.37e-272	yttB	-	-	EGP	-	-	-	Major Facilitator
AKFMHANA_00976	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
AKFMHANA_00977	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
AKFMHANA_00978	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
AKFMHANA_00979	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AKFMHANA_00980	1.03e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AKFMHANA_00981	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
AKFMHANA_00982	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AKFMHANA_00983	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AKFMHANA_00984	2.07e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AKFMHANA_00985	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
AKFMHANA_00986	8.49e-265	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AKFMHANA_00987	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AKFMHANA_00988	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
AKFMHANA_00989	9.81e-77	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AKFMHANA_00990	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AKFMHANA_00991	3.01e-177	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
AKFMHANA_00992	1.77e-288	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
AKFMHANA_00993	2.15e-121	-	-	-	-	-	-	-	-
AKFMHANA_00994	8.92e-87	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
AKFMHANA_00995	4.05e-221	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
AKFMHANA_00996	1.53e-188	epsB	-	-	M	-	-	-	biosynthesis protein
AKFMHANA_00997	1.63e-158	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
AKFMHANA_00998	2.64e-136	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
AKFMHANA_00999	3.73e-94	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
AKFMHANA_01000	9.76e-66	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
AKFMHANA_01002	7.52e-32	-	-	-	M	-	-	-	Glycosyltransferase like family 2
AKFMHANA_01003	1.53e-55	-	-	-	M	-	-	-	Glycosyl transferases group 1
AKFMHANA_01004	4.89e-50	-	-	-	M	-	-	-	Glycosyltransferase like family 2
AKFMHANA_01005	1.7e-26	-	2.4.1.56	GT4,GT9	M	ko:K03280	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
AKFMHANA_01006	2.15e-75	-	-	-	M	-	-	-	Glycosyltransferase like family 2
AKFMHANA_01007	3.38e-106	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
AKFMHANA_01008	8.06e-111	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
AKFMHANA_01009	1.16e-120	-	4.2.1.46	-	GM	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
AKFMHANA_01010	5.35e-69	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
AKFMHANA_01011	2.13e-142	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
AKFMHANA_01012	5.9e-145	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
AKFMHANA_01013	4.14e-94	isp	-	-	L	-	-	-	Transposase
AKFMHANA_01014	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
AKFMHANA_01015	1.52e-263	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AKFMHANA_01016	4.93e-24	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
AKFMHANA_01017	2.71e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
AKFMHANA_01018	0.0	snf	-	-	KL	-	-	-	domain protein
AKFMHANA_01020	2.74e-50	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
AKFMHANA_01021	1.25e-89	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
AKFMHANA_01022	1.91e-142	-	-	-	L	-	-	-	PFAM Integrase catalytic region
AKFMHANA_01023	2.4e-315	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
AKFMHANA_01024	5.14e-217	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
AKFMHANA_01026	7.28e-64	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
AKFMHANA_01027	1.62e-29	-	-	-	S	-	-	-	Region found in RelA / SpoT proteins
AKFMHANA_01028	5.42e-276	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
AKFMHANA_01029	6.61e-194	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AKFMHANA_01030	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
AKFMHANA_01031	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
AKFMHANA_01032	2.32e-179	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
AKFMHANA_01033	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
AKFMHANA_01034	2.28e-137	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
AKFMHANA_01035	3.74e-204	yvgN	-	-	S	-	-	-	Aldo keto reductase
AKFMHANA_01036	1.3e-265	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
AKFMHANA_01037	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
AKFMHANA_01038	3.61e-61	-	-	-	-	-	-	-	-
AKFMHANA_01039	4.83e-312	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
AKFMHANA_01040	3.65e-114	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
AKFMHANA_01041	1.14e-27	-	-	-	-	-	-	-	-
AKFMHANA_01042	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
AKFMHANA_01043	4.16e-180	-	-	-	S	-	-	-	Membrane
AKFMHANA_01044	1.24e-182	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
AKFMHANA_01045	2.19e-116	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
AKFMHANA_01046	1.66e-286	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
AKFMHANA_01047	1.93e-208	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
AKFMHANA_01048	2.44e-20	-	-	-	-	-	-	-	-
AKFMHANA_01049	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AKFMHANA_01050	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AKFMHANA_01051	2.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AKFMHANA_01052	1.75e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
AKFMHANA_01053	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
AKFMHANA_01054	1.25e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AKFMHANA_01055	7.41e-130	-	-	-	-	-	-	-	-
AKFMHANA_01057	3.18e-167	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AKFMHANA_01058	1.49e-272	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
AKFMHANA_01059	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AKFMHANA_01060	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
AKFMHANA_01061	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
AKFMHANA_01062	1.84e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
AKFMHANA_01063	2.92e-182	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
AKFMHANA_01064	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
AKFMHANA_01065	8.74e-235	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AKFMHANA_01066	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
AKFMHANA_01067	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AKFMHANA_01068	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
AKFMHANA_01069	7.32e-124	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AKFMHANA_01070	2.63e-53	-	-	-	-	-	-	-	-
AKFMHANA_01071	0.0	ydaO	-	-	E	-	-	-	amino acid
AKFMHANA_01072	0.0	-	-	-	E	-	-	-	amino acid
AKFMHANA_01073	3.5e-112	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
AKFMHANA_01074	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AKFMHANA_01075	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AKFMHANA_01077	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AKFMHANA_01078	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
AKFMHANA_01079	2.61e-236	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AKFMHANA_01080	1.37e-292	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
AKFMHANA_01081	3.05e-189	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
AKFMHANA_01082	2.29e-180	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AKFMHANA_01083	3.8e-292	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AKFMHANA_01084	1.87e-172	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AKFMHANA_01085	7.09e-252	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AKFMHANA_01086	3.02e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
AKFMHANA_01087	1.18e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
AKFMHANA_01088	1.1e-147	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
AKFMHANA_01091	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
AKFMHANA_01092	2.34e-205	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
AKFMHANA_01095	5.92e-150	-	-	-	-	-	-	-	-
AKFMHANA_01096	0.0	-	-	-	EGP	-	-	-	Major Facilitator
AKFMHANA_01097	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
AKFMHANA_01098	5.9e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
AKFMHANA_01099	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
AKFMHANA_01100	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AKFMHANA_01101	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AKFMHANA_01102	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
AKFMHANA_01103	2e-112	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
AKFMHANA_01105	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
AKFMHANA_01106	5.72e-239	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
AKFMHANA_01107	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
AKFMHANA_01108	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AKFMHANA_01109	1.27e-215	-	-	-	I	-	-	-	alpha/beta hydrolase fold
AKFMHANA_01110	4.46e-276	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
AKFMHANA_01111	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AKFMHANA_01112	1.75e-173	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_01113	3.01e-181	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
AKFMHANA_01114	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
AKFMHANA_01115	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AKFMHANA_01116	1.65e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
AKFMHANA_01117	1.02e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
AKFMHANA_01118	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AKFMHANA_01119	2.09e-265	yacL	-	-	S	-	-	-	domain protein
AKFMHANA_01120	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
AKFMHANA_01121	2.16e-94	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AKFMHANA_01122	1.82e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKFMHANA_01123	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
AKFMHANA_01124	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
AKFMHANA_01125	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
AKFMHANA_01126	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AKFMHANA_01127	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AKFMHANA_01128	9.63e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
AKFMHANA_01130	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
AKFMHANA_01131	3.1e-268	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
AKFMHANA_01132	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AKFMHANA_01133	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AKFMHANA_01134	2.39e-64	-	-	-	-	-	-	-	-
AKFMHANA_01136	1.9e-61	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AKFMHANA_01137	2.79e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
AKFMHANA_01138	1.09e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
AKFMHANA_01139	6.81e-172	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
AKFMHANA_01140	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
AKFMHANA_01141	7.68e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKFMHANA_01142	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKFMHANA_01143	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
AKFMHANA_01144	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AKFMHANA_01145	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AKFMHANA_01146	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AKFMHANA_01147	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AKFMHANA_01148	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
AKFMHANA_01149	5.48e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AKFMHANA_01150	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
AKFMHANA_01151	1.29e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
AKFMHANA_01152	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
AKFMHANA_01153	5.48e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AKFMHANA_01154	1.82e-177	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
AKFMHANA_01155	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
AKFMHANA_01156	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AKFMHANA_01157	5.83e-225	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
AKFMHANA_01158	1.48e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
AKFMHANA_01159	9.94e-176	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
AKFMHANA_01160	1.94e-49	-	-	-	S	-	-	-	Double zinc ribbon
AKFMHANA_01161	1.19e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
AKFMHANA_01162	6.65e-234	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
AKFMHANA_01163	3.14e-177	-	-	-	IQ	-	-	-	KR domain
AKFMHANA_01164	7.29e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
AKFMHANA_01165	5.18e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
AKFMHANA_01166	1.45e-315	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_01167	2.39e-146	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
AKFMHANA_01168	6.5e-71	-	-	-	-	-	-	-	-
AKFMHANA_01169	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
AKFMHANA_01170	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
AKFMHANA_01171	1.25e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
AKFMHANA_01172	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
AKFMHANA_01173	1.92e-204	-	-	-	-	-	-	-	-
AKFMHANA_01174	1.76e-233	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
AKFMHANA_01175	4e-175	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
AKFMHANA_01176	1.38e-97	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
AKFMHANA_01177	2.77e-270	-	-	-	EGP	-	-	-	Major Facilitator
AKFMHANA_01178	3.83e-153	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
AKFMHANA_01179	1.64e-252	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
AKFMHANA_01180	3.34e-107	-	-	-	-	-	-	-	-
AKFMHANA_01181	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
AKFMHANA_01182	8.79e-107	-	-	-	T	-	-	-	EAL domain
AKFMHANA_01183	9.34e-59	-	-	-	T	-	-	-	EAL domain
AKFMHANA_01184	8.44e-168	-	-	-	F	-	-	-	glutamine amidotransferase
AKFMHANA_01185	8.96e-79	-	-	-	-	-	-	-	-
AKFMHANA_01186	1.28e-125	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
AKFMHANA_01187	9.48e-204	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
AKFMHANA_01188	2.62e-184	-	-	-	K	-	-	-	Transcriptional regulator
AKFMHANA_01189	2.82e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
AKFMHANA_01190	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
AKFMHANA_01191	1.17e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
AKFMHANA_01192	3.79e-222	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
AKFMHANA_01193	1.2e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
AKFMHANA_01194	8.13e-182	-	-	-	S	-	-	-	Alpha beta hydrolase
AKFMHANA_01195	1.64e-105	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
AKFMHANA_01196	1.48e-72	lysR	-	-	K	-	-	-	Transcriptional regulator
AKFMHANA_01197	1.48e-162	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
AKFMHANA_01199	1.78e-210	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
AKFMHANA_01200	1.04e-149	-	-	-	L	-	-	-	Type I restriction modification DNA specificity domain
AKFMHANA_01201	1.02e-228	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
AKFMHANA_01202	2.49e-82	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
AKFMHANA_01203	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
AKFMHANA_01204	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
AKFMHANA_01205	1.48e-178	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
AKFMHANA_01206	2.75e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
AKFMHANA_01207	1.26e-60	-	-	-	-	-	-	-	-
AKFMHANA_01208	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
AKFMHANA_01209	2.58e-41	-	-	-	-	-	-	-	-
AKFMHANA_01210	3.8e-63	-	-	-	-	-	-	-	-
AKFMHANA_01211	2.93e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
AKFMHANA_01212	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
AKFMHANA_01213	5.67e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
AKFMHANA_01214	1.8e-226	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AKFMHANA_01215	4.82e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
AKFMHANA_01216	1.88e-292	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
AKFMHANA_01217	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AKFMHANA_01218	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
AKFMHANA_01219	9.69e-38	-	-	-	-	-	-	-	-
AKFMHANA_01220	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
AKFMHANA_01221	6.36e-130	-	-	-	S	-	-	-	Pfam:DUF3816
AKFMHANA_01222	1.57e-181	-	-	-	G	-	-	-	MucBP domain
AKFMHANA_01223	1.27e-151	-	-	-	-	-	-	-	-
AKFMHANA_01224	2.62e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_01225	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
AKFMHANA_01226	3.07e-240	-	-	-	L	-	-	-	PFAM Integrase catalytic region
AKFMHANA_01227	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AKFMHANA_01228	4.39e-297	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
AKFMHANA_01229	6.09e-162	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
AKFMHANA_01230	3.14e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AKFMHANA_01231	2.7e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
AKFMHANA_01232	1.95e-195	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
AKFMHANA_01233	1.71e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
AKFMHANA_01234	2.8e-168	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
AKFMHANA_01235	9.42e-174	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AKFMHANA_01236	4.06e-184	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
AKFMHANA_01237	2.33e-238	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
AKFMHANA_01238	4.2e-96	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AKFMHANA_01239	2e-56	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AKFMHANA_01240	9.18e-207	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AKFMHANA_01241	1.4e-145	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AKFMHANA_01242	4.15e-170	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AKFMHANA_01243	3.08e-102	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AKFMHANA_01244	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
AKFMHANA_01245	1.15e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
AKFMHANA_01246	8.76e-63	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
AKFMHANA_01247	3.59e-128	-	-	-	S	-	-	-	AmiS/UreI family transporter
AKFMHANA_01248	1.31e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
AKFMHANA_01249	8.88e-48	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
AKFMHANA_01250	1.42e-190	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
AKFMHANA_01251	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
AKFMHANA_01252	3.25e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
AKFMHANA_01253	2.76e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
AKFMHANA_01254	1.29e-156	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
AKFMHANA_01257	4.84e-233	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
AKFMHANA_01258	1.49e-69	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
AKFMHANA_01259	5e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AKFMHANA_01260	1.73e-215	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
AKFMHANA_01261	8.95e-292	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
AKFMHANA_01262	5.88e-164	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
AKFMHANA_01263	5.6e-70	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
AKFMHANA_01264	4.96e-152	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
AKFMHANA_01265	7.74e-202	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
AKFMHANA_01266	1.49e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
AKFMHANA_01267	1.78e-204	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
AKFMHANA_01268	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
AKFMHANA_01271	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AKFMHANA_01272	6.69e-213	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
AKFMHANA_01273	6.83e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
AKFMHANA_01274	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
AKFMHANA_01275	1.27e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AKFMHANA_01276	7.82e-80	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AKFMHANA_01277	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AKFMHANA_01278	4.15e-192	-	-	-	S	-	-	-	DUF218 domain
AKFMHANA_01279	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
AKFMHANA_01280	9.45e-315	yhdP	-	-	S	-	-	-	Transporter associated domain
AKFMHANA_01281	5.47e-55	-	-	-	S	-	-	-	Cytochrome B5
AKFMHANA_01282	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
AKFMHANA_01283	2.3e-52	-	-	-	S	-	-	-	Cytochrome B5
AKFMHANA_01284	7.65e-101	-	-	-	S	ko:K02348	-	ko00000	Gnat family
AKFMHANA_01285	6.67e-158	-	-	-	GM	-	-	-	NmrA-like family
AKFMHANA_01286	2.74e-69	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
AKFMHANA_01287	1.41e-141	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
AKFMHANA_01288	1.85e-108	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
AKFMHANA_01289	2.05e-294	-	-	-	-	-	-	-	-
AKFMHANA_01290	2.65e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
AKFMHANA_01291	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
AKFMHANA_01292	8.37e-145	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
AKFMHANA_01293	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
AKFMHANA_01294	7.58e-63	ywnA	-	-	K	-	-	-	Transcriptional regulator
AKFMHANA_01295	4.39e-120	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
AKFMHANA_01296	2.03e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
AKFMHANA_01297	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
AKFMHANA_01298	5.39e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
AKFMHANA_01299	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
AKFMHANA_01300	4.86e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
AKFMHANA_01301	0.0	yagE	-	-	E	-	-	-	amino acid
AKFMHANA_01302	1.57e-150	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
AKFMHANA_01303	1.53e-38	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
AKFMHANA_01304	3.99e-196	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
AKFMHANA_01306	7.17e-177	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
AKFMHANA_01307	9.68e-29	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
AKFMHANA_01309	3.64e-13	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
AKFMHANA_01311	5.29e-170	-	-	-	-	-	-	-	-
AKFMHANA_01312	2.64e-169	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
AKFMHANA_01313	1.17e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
AKFMHANA_01314	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
AKFMHANA_01315	4.96e-216	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
AKFMHANA_01316	4.15e-282	arcT	-	-	E	-	-	-	Aminotransferase
AKFMHANA_01317	1.24e-201	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
AKFMHANA_01318	9.04e-90	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
AKFMHANA_01319	0.0	potE	-	-	E	-	-	-	Amino Acid
AKFMHANA_01320	9.09e-204	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
AKFMHANA_01321	8.85e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
AKFMHANA_01322	6.21e-43	-	-	-	-	-	-	-	-
AKFMHANA_01323	6.03e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
AKFMHANA_01324	1.29e-187	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
AKFMHANA_01325	7.67e-223	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
AKFMHANA_01326	6.93e-154	-	-	-	M	-	-	-	Bacterial sugar transferase
AKFMHANA_01327	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
AKFMHANA_01328	1.89e-171	-	-	-	IQ	-	-	-	dehydrogenase reductase
AKFMHANA_01329	2.33e-51	-	-	-	-	-	-	-	-
AKFMHANA_01330	1.39e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
AKFMHANA_01331	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
AKFMHANA_01332	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
AKFMHANA_01333	9.76e-233	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AKFMHANA_01335	2.5e-132	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
AKFMHANA_01336	1.26e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
AKFMHANA_01337	5.03e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AKFMHANA_01339	6.14e-233	ydhF	-	-	S	-	-	-	Aldo keto reductase
AKFMHANA_01340	3.6e-107	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
AKFMHANA_01341	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
AKFMHANA_01343	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
AKFMHANA_01344	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
AKFMHANA_01345	1.11e-131	-	-	-	-	-	-	-	-
AKFMHANA_01346	3e-167	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
AKFMHANA_01347	0.0	cadA	-	-	P	-	-	-	P-type ATPase
AKFMHANA_01348	6.49e-288	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
AKFMHANA_01349	4.44e-11	-	-	-	-	-	-	-	-
AKFMHANA_01350	6.39e-198	-	-	-	GM	-	-	-	NAD(P)H-binding
AKFMHANA_01351	1.11e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
AKFMHANA_01352	5.3e-209	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
AKFMHANA_01353	2.35e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AKFMHANA_01354	4.13e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_01355	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
AKFMHANA_01356	1.05e-101	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
AKFMHANA_01357	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
AKFMHANA_01358	6.12e-279	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
AKFMHANA_01359	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AKFMHANA_01360	1.04e-245	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AKFMHANA_01361	1.45e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
AKFMHANA_01362	5.14e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
AKFMHANA_01363	1.63e-278	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
AKFMHANA_01364	9.57e-52	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
AKFMHANA_01365	8.11e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AKFMHANA_01366	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
AKFMHANA_01367	1.09e-244	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AKFMHANA_01368	8.93e-31	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AKFMHANA_01370	1.57e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AKFMHANA_01371	0.0	-	-	-	L	-	-	-	DNA helicase
AKFMHANA_01372	1.17e-105	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
AKFMHANA_01373	6.68e-238	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
AKFMHANA_01374	1.3e-241	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
AKFMHANA_01375	4.38e-215	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
AKFMHANA_01376	3.28e-296	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
AKFMHANA_01377	1.33e-228	-	-	-	-	-	-	-	-
AKFMHANA_01378	1.51e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
AKFMHANA_01380	9.18e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
AKFMHANA_01381	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AKFMHANA_01382	1.77e-198	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
AKFMHANA_01383	1.04e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AKFMHANA_01384	3.58e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AKFMHANA_01385	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
AKFMHANA_01386	1.71e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AKFMHANA_01387	8.21e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
AKFMHANA_01388	3.28e-156	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
AKFMHANA_01389	5.02e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
AKFMHANA_01390	3.47e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
AKFMHANA_01391	4.57e-316	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AKFMHANA_01392	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AKFMHANA_01393	2.87e-96	-	-	-	-	-	-	-	-
AKFMHANA_01394	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
AKFMHANA_01395	6.51e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
AKFMHANA_01396	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
AKFMHANA_01397	2.95e-239	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AKFMHANA_01398	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AKFMHANA_01399	2.2e-129	-	-	-	-	-	-	-	-
AKFMHANA_01400	4.46e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AKFMHANA_01402	3.62e-308	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
AKFMHANA_01403	4.72e-107	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
AKFMHANA_01404	8.71e-178	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
AKFMHANA_01405	5.46e-315	-	-	-	E	-	-	-	amino acid
AKFMHANA_01406	1.64e-18	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
AKFMHANA_01407	4.39e-94	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
AKFMHANA_01408	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AKFMHANA_01409	3.99e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_01410	2.25e-288	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
AKFMHANA_01411	1.69e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
AKFMHANA_01412	2.47e-220	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
AKFMHANA_01413	1.08e-210	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
AKFMHANA_01414	9.71e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
AKFMHANA_01415	3.57e-198	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
AKFMHANA_01416	8.34e-180	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
AKFMHANA_01417	3.96e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
AKFMHANA_01418	8.24e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
AKFMHANA_01419	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AKFMHANA_01420	6.3e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
AKFMHANA_01421	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
AKFMHANA_01422	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
AKFMHANA_01423	1.19e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AKFMHANA_01424	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AKFMHANA_01425	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AKFMHANA_01426	1.52e-209	-	-	-	S	-	-	-	Tetratricopeptide repeat
AKFMHANA_01427	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AKFMHANA_01428	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AKFMHANA_01429	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
AKFMHANA_01430	5.84e-203	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
AKFMHANA_01431	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
AKFMHANA_01432	5e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
AKFMHANA_01433	8.7e-141	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
AKFMHANA_01434	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
AKFMHANA_01436	8.77e-282	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
AKFMHANA_01437	8.32e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
AKFMHANA_01438	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AKFMHANA_01439	6.44e-205	-	-	-	EG	-	-	-	EamA-like transporter family
AKFMHANA_01440	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
AKFMHANA_01441	1.14e-312	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
AKFMHANA_01442	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
AKFMHANA_01443	5.09e-162	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
AKFMHANA_01445	5.74e-62	-	-	-	-	-	-	-	-
AKFMHANA_01446	1.02e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
AKFMHANA_01447	1.48e-187	-	-	-	S	-	-	-	Alpha beta hydrolase
AKFMHANA_01448	5.74e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
AKFMHANA_01449	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AKFMHANA_01450	1.77e-56	-	-	-	-	-	-	-	-
AKFMHANA_01451	9.13e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
AKFMHANA_01452	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
AKFMHANA_01453	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
AKFMHANA_01454	2.29e-130	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
AKFMHANA_01455	9.83e-316	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
AKFMHANA_01456	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
AKFMHANA_01457	1.37e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AKFMHANA_01458	7.9e-214	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
AKFMHANA_01459	6.73e-149	-	-	-	M	-	-	-	LysM domain protein
AKFMHANA_01460	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
AKFMHANA_01461	4.57e-137	-	-	-	M	-	-	-	LysM domain protein
AKFMHANA_01462	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AKFMHANA_01463	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
AKFMHANA_01464	4.83e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AKFMHANA_01465	2.51e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AKFMHANA_01466	2.23e-209	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
AKFMHANA_01467	7.69e-170	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
AKFMHANA_01468	1.27e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AKFMHANA_01469	1.3e-99	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AKFMHANA_01470	1.38e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AKFMHANA_01471	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
AKFMHANA_01472	7.2e-185	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AKFMHANA_01473	9.73e-180	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
AKFMHANA_01474	4.25e-172	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
AKFMHANA_01481	2.24e-200	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
AKFMHANA_01482	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AKFMHANA_01483	6.53e-220	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
AKFMHANA_01484	1.92e-209	-	-	-	EG	-	-	-	EamA-like transporter family
AKFMHANA_01485	1.04e-135	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
AKFMHANA_01486	1.53e-71	-	-	-	S	-	-	-	Cupredoxin-like domain
AKFMHANA_01487	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
AKFMHANA_01488	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
AKFMHANA_01489	1.69e-117	-	-	-	-	-	-	-	-
AKFMHANA_01491	1.28e-75	-	-	-	-	-	-	-	-
AKFMHANA_01492	1.05e-305	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
AKFMHANA_01494	6.17e-301	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
AKFMHANA_01495	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
AKFMHANA_01496	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
AKFMHANA_01497	7.24e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
AKFMHANA_01498	3e-251	ampC	-	-	V	-	-	-	Beta-lactamase
AKFMHANA_01499	2.51e-83	-	-	-	-	-	-	-	-
AKFMHANA_01500	0.0	-	-	-	M	-	-	-	domain protein
AKFMHANA_01501	1.01e-42	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
AKFMHANA_01503	1.04e-115	-	-	-	-	-	-	-	-
AKFMHANA_01505	1.39e-169	-	-	-	F	-	-	-	NUDIX domain
AKFMHANA_01506	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AKFMHANA_01507	3.53e-135	pncA	-	-	Q	-	-	-	Isochorismatase family
AKFMHANA_01508	2.34e-266	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
AKFMHANA_01509	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
AKFMHANA_01510	1.72e-212	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
AKFMHANA_01511	1.07e-52	hxlR	-	-	K	-	-	-	regulation of RNA biosynthetic process
AKFMHANA_01512	5.81e-295	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
AKFMHANA_01514	7.53e-191	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
AKFMHANA_01515	1.8e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
AKFMHANA_01516	1.39e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
AKFMHANA_01517	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AKFMHANA_01518	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
AKFMHANA_01519	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AKFMHANA_01520	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AKFMHANA_01521	3.31e-263	-	-	-	-	-	-	-	-
AKFMHANA_01522	1.44e-155	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
AKFMHANA_01523	3.56e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AKFMHANA_01524	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AKFMHANA_01525	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AKFMHANA_01526	2.58e-254	-	-	-	L	-	-	-	Transposase
AKFMHANA_01527	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
AKFMHANA_01528	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AKFMHANA_01529	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
AKFMHANA_01530	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AKFMHANA_01531	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AKFMHANA_01532	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AKFMHANA_01533	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AKFMHANA_01534	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AKFMHANA_01535	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AKFMHANA_01536	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
AKFMHANA_01537	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AKFMHANA_01538	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AKFMHANA_01539	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AKFMHANA_01540	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AKFMHANA_01541	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AKFMHANA_01542	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AKFMHANA_01543	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AKFMHANA_01544	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AKFMHANA_01545	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
AKFMHANA_01546	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
AKFMHANA_01547	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AKFMHANA_01548	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AKFMHANA_01549	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AKFMHANA_01550	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
AKFMHANA_01551	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AKFMHANA_01552	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AKFMHANA_01553	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AKFMHANA_01554	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
AKFMHANA_01555	2.21e-189	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AKFMHANA_01556	2.14e-198	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AKFMHANA_01557	5.82e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AKFMHANA_01558	1.23e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AKFMHANA_01559	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AKFMHANA_01560	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
AKFMHANA_01561	1.56e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
AKFMHANA_01562	5.09e-148	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
AKFMHANA_01563	4.76e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AKFMHANA_01564	3.24e-272	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AKFMHANA_01565	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
AKFMHANA_01566	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AKFMHANA_01567	3.17e-260	camS	-	-	S	-	-	-	sex pheromone
AKFMHANA_01568	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKFMHANA_01569	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AKFMHANA_01570	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKFMHANA_01571	2.72e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
AKFMHANA_01573	5.1e-45	-	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
AKFMHANA_01574	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AKFMHANA_01575	2.79e-61	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
AKFMHANA_01576	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
AKFMHANA_01577	3.24e-16	-	-	-	-	-	-	-	-
AKFMHANA_01580	4.28e-225	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
AKFMHANA_01581	1.52e-198	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AKFMHANA_01582	9.06e-151	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
AKFMHANA_01583	2.51e-150	yjbH	-	-	Q	-	-	-	Thioredoxin
AKFMHANA_01584	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
AKFMHANA_01585	1.25e-142	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
AKFMHANA_01586	3.9e-40	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
AKFMHANA_01587	5.67e-157	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AKFMHANA_01588	4.08e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AKFMHANA_01589	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
AKFMHANA_01609	5.53e-24	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AKFMHANA_01610	1.06e-48	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AKFMHANA_01611	9.78e-148	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AKFMHANA_01612	1.76e-162	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
AKFMHANA_01613	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AKFMHANA_01614	3.49e-192	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
AKFMHANA_01615	1.56e-59	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
AKFMHANA_01616	8.13e-153	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
AKFMHANA_01617	8.12e-46	-	-	-	LM	-	-	-	gp58-like protein
AKFMHANA_01624	7.69e-45	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
AKFMHANA_01625	1.03e-185	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
AKFMHANA_01627	8.53e-95	-	-	-	-	-	-	-	-
AKFMHANA_01628	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
AKFMHANA_01629	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
AKFMHANA_01630	0.0	-	-	-	M	-	-	-	domain protein
AKFMHANA_01631	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
AKFMHANA_01632	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
AKFMHANA_01633	8.54e-34	-	-	-	-	-	-	-	-
AKFMHANA_01634	1.53e-127	-	-	-	K	-	-	-	DNA-templated transcription, initiation
AKFMHANA_01635	3.82e-47	-	-	-	-	-	-	-	-
AKFMHANA_01636	2.26e-115	-	-	-	-	-	-	-	-
AKFMHANA_01637	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AKFMHANA_01638	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
AKFMHANA_01639	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
AKFMHANA_01640	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
AKFMHANA_01641	5.67e-313	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
AKFMHANA_01642	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
AKFMHANA_01643	1.08e-221	yvgN	-	-	C	-	-	-	Aldo keto reductase
AKFMHANA_01644	2.08e-208	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
AKFMHANA_01645	3.15e-113	-	-	-	C	-	-	-	Flavodoxin
AKFMHANA_01646	9.07e-106	-	-	-	S	-	-	-	Cupin domain
AKFMHANA_01647	1.35e-97	-	-	-	S	-	-	-	UPF0756 membrane protein
AKFMHANA_01648	1.44e-309	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
AKFMHANA_01649	1.68e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
AKFMHANA_01650	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
AKFMHANA_01651	3.22e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
AKFMHANA_01652	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
AKFMHANA_01653	2.07e-236	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
AKFMHANA_01654	7.48e-69	-	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
AKFMHANA_01655	1.1e-06	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
AKFMHANA_01656	5.12e-126	-	-	-	-	-	-	-	-
AKFMHANA_01657	2.97e-105	-	-	-	L	-	-	-	AAA domain
AKFMHANA_01658	3.27e-125	-	-	-	L	-	-	-	AAA ATPase domain
AKFMHANA_01659	1.24e-83	-	-	-	C	-	-	-	Flavodoxin
AKFMHANA_01660	1.15e-15	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
AKFMHANA_01661	2e-73	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
AKFMHANA_01662	6.2e-155	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
AKFMHANA_01663	5.77e-291	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
AKFMHANA_01664	5.46e-207	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
AKFMHANA_01665	2.58e-154	-	-	-	H	-	-	-	RibD C-terminal domain
AKFMHANA_01667	7.11e-57	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
AKFMHANA_01668	5.07e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
AKFMHANA_01669	2.7e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
AKFMHANA_01670	3.57e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
AKFMHANA_01671	5.57e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
AKFMHANA_01672	5.02e-29	-	-	-	-	-	-	-	-
AKFMHANA_01673	1.38e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
AKFMHANA_01674	3.73e-203	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
AKFMHANA_01675	1.94e-64	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
AKFMHANA_01677	3.01e-63	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
AKFMHANA_01678	3.83e-06	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AKFMHANA_01679	3.7e-11	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
AKFMHANA_01683	1.24e-56	-	-	-	S	-	-	-	calcium ion binding
AKFMHANA_01685	5.75e-37	-	-	-	-	-	-	-	-
AKFMHANA_01686	2.41e-20	-	-	-	-	-	-	-	-
AKFMHANA_01687	2.57e-23	-	-	-	S	-	-	-	sequence-specific DNA binding
AKFMHANA_01688	4.02e-53	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
AKFMHANA_01694	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
AKFMHANA_01695	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
AKFMHANA_01696	8.71e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
AKFMHANA_01697	2.79e-153	-	-	-	I	-	-	-	phosphatase
AKFMHANA_01698	2.59e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
AKFMHANA_01699	7.95e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
AKFMHANA_01700	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
AKFMHANA_01701	2.32e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
AKFMHANA_01702	4.04e-212	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
AKFMHANA_01703	3.11e-153	-	-	-	S	-	-	-	membrane
AKFMHANA_01704	4.71e-142	-	-	-	S	-	-	-	VIT family
AKFMHANA_01705	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
AKFMHANA_01706	4.64e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_01707	9.45e-196	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
AKFMHANA_01708	5.24e-143	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AKFMHANA_01709	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
AKFMHANA_01710	8.11e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
AKFMHANA_01711	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AKFMHANA_01712	8.46e-77	-	-	-	-	-	-	-	-
AKFMHANA_01713	5.33e-98	-	-	-	K	-	-	-	MerR HTH family regulatory protein
AKFMHANA_01714	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
AKFMHANA_01715	6.51e-161	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
AKFMHANA_01716	3.34e-212	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
AKFMHANA_01718	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AKFMHANA_01719	1.17e-135	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
AKFMHANA_01720	2.74e-241	-	-	-	I	-	-	-	Alpha beta
AKFMHANA_01721	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
AKFMHANA_01722	7.76e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
AKFMHANA_01723	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
AKFMHANA_01724	7.21e-205	-	-	-	K	-	-	-	LysR family
AKFMHANA_01725	1.03e-142	-	-	-	I	-	-	-	Alpha/beta hydrolase family
AKFMHANA_01726	1.56e-193	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
AKFMHANA_01727	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
AKFMHANA_01728	3.29e-204	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
AKFMHANA_01729	2.56e-56	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
AKFMHANA_01730	9.38e-188	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AKFMHANA_01731	1.15e-223	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
AKFMHANA_01732	2.38e-155	citR	-	-	K	-	-	-	sugar-binding domain protein
AKFMHANA_01733	1.01e-214	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
AKFMHANA_01734	1.85e-163	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
AKFMHANA_01735	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
AKFMHANA_01736	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
AKFMHANA_01737	3.63e-244	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
AKFMHANA_01738	3.14e-119	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
AKFMHANA_01739	1.3e-206	mleR	-	-	K	-	-	-	LysR family
AKFMHANA_01740	8.22e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AKFMHANA_01741	1.15e-264	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
AKFMHANA_01742	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
AKFMHANA_01743	8.63e-213	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
AKFMHANA_01744	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
AKFMHANA_01745	6.92e-31	-	-	-	-	-	-	-	-
AKFMHANA_01746	1.43e-252	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
AKFMHANA_01748	9.13e-125	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AKFMHANA_01749	4.46e-199	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AKFMHANA_01750	1.81e-43	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AKFMHANA_01753	1.58e-126	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
AKFMHANA_01755	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
AKFMHANA_01756	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AKFMHANA_01757	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
AKFMHANA_01758	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
AKFMHANA_01759	2.24e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
AKFMHANA_01760	1.81e-108	-	-	-	-	-	-	-	-
AKFMHANA_01761	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
AKFMHANA_01762	7.7e-311	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AKFMHANA_01763	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
AKFMHANA_01764	7.96e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
AKFMHANA_01765	4.7e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
AKFMHANA_01766	2.98e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
AKFMHANA_01767	2.4e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AKFMHANA_01768	3.2e-239	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
AKFMHANA_01769	6e-132	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
AKFMHANA_01771	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AKFMHANA_01772	1.32e-52	-	-	-	L	-	-	-	PFAM Integrase catalytic region
AKFMHANA_01773	7.25e-204	-	-	-	-	-	-	-	-
AKFMHANA_01774	9.91e-204	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
AKFMHANA_01775	2.39e-239	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
AKFMHANA_01776	2.73e-206	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AKFMHANA_01777	9.64e-141	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
AKFMHANA_01778	2.23e-261	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AKFMHANA_01779	1.02e-196	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AKFMHANA_01780	1.46e-08	-	-	-	S	-	-	-	CsbD-like
AKFMHANA_01781	1.9e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
AKFMHANA_01782	9.15e-301	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AKFMHANA_01783	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
AKFMHANA_01784	1.56e-146	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
AKFMHANA_01785	1.75e-31	-	-	-	K	-	-	-	LytTr DNA-binding domain
AKFMHANA_01786	9.77e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
AKFMHANA_01788	9.91e-219	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
AKFMHANA_01789	5.63e-198	-	-	-	EG	-	-	-	EamA-like transporter family
AKFMHANA_01790	1.15e-152	-	-	-	L	-	-	-	Integrase
AKFMHANA_01791	2.95e-203	rssA	-	-	S	-	-	-	Phospholipase, patatin family
AKFMHANA_01792	6.92e-184	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AKFMHANA_01793	2.03e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
AKFMHANA_01794	9.87e-300	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
AKFMHANA_01795	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AKFMHANA_01796	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AKFMHANA_01797	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
AKFMHANA_01798	3.54e-276	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
AKFMHANA_01799	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
AKFMHANA_01800	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
AKFMHANA_01801	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AKFMHANA_01802	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AKFMHANA_01803	1.48e-216	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AKFMHANA_01804	4.14e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
AKFMHANA_01805	3.09e-85	-	-	-	-	-	-	-	-
AKFMHANA_01806	2.27e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AKFMHANA_01807	2.83e-118	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AKFMHANA_01808	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
AKFMHANA_01809	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AKFMHANA_01810	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AKFMHANA_01811	4.55e-288	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
AKFMHANA_01812	1.7e-182	-	-	-	-	-	-	-	-
AKFMHANA_01813	4.29e-18	-	-	-	-	-	-	-	-
AKFMHANA_01814	2.44e-99	-	-	-	-	-	-	-	-
AKFMHANA_01815	5.09e-107	-	-	-	-	-	-	-	-
AKFMHANA_01816	2.6e-14	-	-	-	K	-	-	-	Peptidase S24-like
AKFMHANA_01817	1.21e-30	-	-	-	K	-	-	-	Peptidase S24-like
AKFMHANA_01818	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
AKFMHANA_01819	3.16e-258	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
AKFMHANA_01820	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
AKFMHANA_01822	3.36e-77	-	-	-	-	-	-	-	-
AKFMHANA_01823	2.15e-234	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
AKFMHANA_01824	1.05e-168	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AKFMHANA_01825	2.38e-72	-	-	-	-	-	-	-	-
AKFMHANA_01826	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AKFMHANA_01827	2.19e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AKFMHANA_01828	1.54e-213	-	-	-	G	-	-	-	Phosphotransferase enzyme family
AKFMHANA_01829	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AKFMHANA_01830	1.89e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
AKFMHANA_01831	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
AKFMHANA_01832	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
AKFMHANA_01833	1.58e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
AKFMHANA_01834	9.82e-234	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
AKFMHANA_01835	1.46e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
AKFMHANA_01836	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
AKFMHANA_01837	7.24e-121	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
AKFMHANA_01838	1.49e-227	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AKFMHANA_01839	6.39e-235	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
AKFMHANA_01840	1.55e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AKFMHANA_01841	1.8e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
AKFMHANA_01842	2.66e-219	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AKFMHANA_01843	1.24e-188	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
AKFMHANA_01844	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
AKFMHANA_01845	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
AKFMHANA_01846	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AKFMHANA_01847	5.12e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AKFMHANA_01848	2.24e-212	-	-	-	I	-	-	-	alpha/beta hydrolase fold
AKFMHANA_01849	2.23e-150	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
AKFMHANA_01850	6.39e-73	-	-	-	-	-	-	-	-
AKFMHANA_01851	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AKFMHANA_01852	6.64e-253	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
AKFMHANA_01853	1.77e-230	yueF	-	-	S	-	-	-	AI-2E family transporter
AKFMHANA_01854	2.97e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AKFMHANA_01855	4.45e-47	-	-	-	-	-	-	-	-
AKFMHANA_01856	5.41e-73	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
AKFMHANA_01857	1.31e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
AKFMHANA_01858	4.42e-216	-	-	-	C	-	-	-	Aldo keto reductase
AKFMHANA_01859	1.29e-176	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
AKFMHANA_01860	3.43e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
AKFMHANA_01861	5.43e-191	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
AKFMHANA_01862	6.98e-40	-	-	-	-	-	-	-	-
AKFMHANA_01863	2.82e-233	-	-	-	G	-	-	-	Peptidase_C39 like family
AKFMHANA_01864	8.4e-259	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
AKFMHANA_01866	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
AKFMHANA_01867	1.2e-268	-	-	-	P	-	-	-	Voltage gated chloride channel
AKFMHANA_01868	5.59e-290	sptS	-	-	T	-	-	-	Histidine kinase
AKFMHANA_01869	1.1e-153	dltr	-	-	K	-	-	-	response regulator
AKFMHANA_01870	2.92e-111	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
AKFMHANA_01871	2.46e-93	-	-	-	-	-	-	-	-
AKFMHANA_01872	4.32e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
AKFMHANA_01873	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
AKFMHANA_01874	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
AKFMHANA_01875	4.84e-277	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
AKFMHANA_01876	9.34e-225	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
AKFMHANA_01877	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
AKFMHANA_01878	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
AKFMHANA_01879	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AKFMHANA_01880	1.22e-139	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
AKFMHANA_01882	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
AKFMHANA_01883	8.68e-44	-	-	-	-	-	-	-	-
AKFMHANA_01884	2.83e-282	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
AKFMHANA_01885	5.24e-232	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AKFMHANA_01886	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
AKFMHANA_01887	1.37e-35	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
AKFMHANA_01890	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
AKFMHANA_01891	7.63e-64	-	-	-	-	-	-	-	-
AKFMHANA_01893	3.16e-278	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
AKFMHANA_01894	1.69e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
AKFMHANA_01895	2.77e-166	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKFMHANA_01896	1.71e-24	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKFMHANA_01897	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
AKFMHANA_01898	2.13e-189	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AKFMHANA_01899	1.52e-192	-	-	-	E	-	-	-	Glyoxalase-like domain
AKFMHANA_01900	1.39e-198	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
AKFMHANA_01901	1.08e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
AKFMHANA_01902	1.56e-125	-	-	-	S	-	-	-	reductase
AKFMHANA_01904	2.63e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AKFMHANA_01905	1.02e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
AKFMHANA_01906	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
AKFMHANA_01907	6.24e-287	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
AKFMHANA_01908	3.06e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
AKFMHANA_01909	6.38e-196	yycI	-	-	S	-	-	-	YycH protein
AKFMHANA_01910	0.0	yycH	-	-	S	-	-	-	YycH protein
AKFMHANA_01911	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
AKFMHANA_01912	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
AKFMHANA_01914	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
AKFMHANA_01915	6.55e-97	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
AKFMHANA_01917	2.86e-74	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
AKFMHANA_01918	1.14e-300	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
AKFMHANA_01919	6.69e-304	-	-	-	L	-	-	-	Integrase core domain
AKFMHANA_01920	3.34e-74	-	-	-	L	-	-	-	Helix-turn-helix domain
AKFMHANA_01921	7.41e-180	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
AKFMHANA_01922	1.64e-142	-	-	-	-	-	-	-	-
AKFMHANA_01923	1.88e-211	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
AKFMHANA_01932	9.17e-59	-	-	-	-	-	-	-	-
AKFMHANA_01933	2.63e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
AKFMHANA_01934	1.2e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
AKFMHANA_01935	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
AKFMHANA_01936	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AKFMHANA_01937	1.36e-136	-	-	-	-	-	-	-	-
AKFMHANA_01938	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AKFMHANA_01939	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AKFMHANA_01940	6.17e-192	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
AKFMHANA_01941	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
AKFMHANA_01942	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
AKFMHANA_01943	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
AKFMHANA_01944	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AKFMHANA_01945	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AKFMHANA_01946	3.1e-289	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
AKFMHANA_01947	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AKFMHANA_01949	2.26e-20	-	-	-	L	-	-	-	Transposase
AKFMHANA_01950	0.0	-	-	-	L	-	-	-	Transposase
AKFMHANA_01951	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AKFMHANA_01952	4.04e-283	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
AKFMHANA_01953	1.83e-21	-	-	-	-	-	-	-	-
AKFMHANA_01955	1.37e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
AKFMHANA_01956	6.97e-240	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
AKFMHANA_01957	3.42e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
AKFMHANA_01958	9.18e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
AKFMHANA_01959	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AKFMHANA_01960	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AKFMHANA_01961	2.12e-19	-	-	-	-	-	-	-	-
AKFMHANA_01962	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
AKFMHANA_01963	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
AKFMHANA_01964	5.98e-116	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
AKFMHANA_01965	5.33e-211	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
AKFMHANA_01966	9.41e-278	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
AKFMHANA_01967	2.04e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AKFMHANA_01968	1.12e-214	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
AKFMHANA_01969	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
AKFMHANA_01970	4.49e-178	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
AKFMHANA_01971	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
AKFMHANA_01972	5.93e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
AKFMHANA_01973	4.38e-205	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AKFMHANA_01974	1.38e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AKFMHANA_01975	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
AKFMHANA_01976	3.65e-67	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
AKFMHANA_01977	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AKFMHANA_01978	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AKFMHANA_01979	3.01e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AKFMHANA_01980	8.07e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
AKFMHANA_01981	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
AKFMHANA_01982	1.4e-146	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
AKFMHANA_01983	0.0	-	-	-	EGP	-	-	-	Major Facilitator
AKFMHANA_01984	3.07e-89	-	-	-	K	-	-	-	Transcriptional regulator