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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HMDFGJHI_00001	5.17e-314	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMDFGJHI_00002	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMDFGJHI_00003	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HMDFGJHI_00004	2.95e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMDFGJHI_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMDFGJHI_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMDFGJHI_00007	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HMDFGJHI_00008	1.68e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMDFGJHI_00009	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMDFGJHI_00010	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HMDFGJHI_00011	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HMDFGJHI_00012	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HMDFGJHI_00013	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HMDFGJHI_00014	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMDFGJHI_00015	3.25e-292	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMDFGJHI_00017	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMDFGJHI_00019	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMDFGJHI_00020	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMDFGJHI_00021	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HMDFGJHI_00022	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HMDFGJHI_00023	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMDFGJHI_00024	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HMDFGJHI_00026	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HMDFGJHI_00027	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HMDFGJHI_00028	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HMDFGJHI_00029	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HMDFGJHI_00030	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HMDFGJHI_00031	2.54e-50	-	-	-	-	-	-	-	-
HMDFGJHI_00033	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HMDFGJHI_00034	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMDFGJHI_00035	3.55e-313	yycH	-	-	S	-	-	-	YycH protein
HMDFGJHI_00036	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HMDFGJHI_00037	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HMDFGJHI_00038	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HMDFGJHI_00039	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMDFGJHI_00040	2e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_00041	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HMDFGJHI_00042	8.48e-215	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HMDFGJHI_00043	2e-155	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HMDFGJHI_00044	1.91e-156	pnb	-	-	C	-	-	-	nitroreductase
HMDFGJHI_00045	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HMDFGJHI_00046	1.57e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HMDFGJHI_00047	0.0	-	-	-	C	-	-	-	FMN_bind
HMDFGJHI_00048	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HMDFGJHI_00049	1.46e-204	-	-	-	K	-	-	-	LysR family
HMDFGJHI_00050	2.49e-95	-	-	-	C	-	-	-	FMN binding
HMDFGJHI_00051	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMDFGJHI_00052	4.06e-211	-	-	-	S	-	-	-	KR domain
HMDFGJHI_00053	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HMDFGJHI_00054	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HMDFGJHI_00055	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HMDFGJHI_00056	3.83e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HMDFGJHI_00057	1.54e-248	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMDFGJHI_00058	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HMDFGJHI_00059	1.62e-173	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HMDFGJHI_00060	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HMDFGJHI_00061	1.65e-106	-	-	-	S	-	-	-	ASCH
HMDFGJHI_00062	3.06e-165	-	-	-	F	-	-	-	glutamine amidotransferase
HMDFGJHI_00063	1.67e-220	-	-	-	K	-	-	-	WYL domain
HMDFGJHI_00064	1.34e-151	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HMDFGJHI_00065	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HMDFGJHI_00066	1.15e-07	-	-	-	S	-	-	-	Protein of unknown function
HMDFGJHI_00067	4.73e-143	-	-	-	S	-	-	-	Protein of unknown function
HMDFGJHI_00068	5e-194	-	-	-	EG	-	-	-	EamA-like transporter family
HMDFGJHI_00069	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HMDFGJHI_00070	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
HMDFGJHI_00071	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HMDFGJHI_00072	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMDFGJHI_00073	5.98e-302	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HMDFGJHI_00074	5.17e-219	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HMDFGJHI_00075	2.14e-178	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HMDFGJHI_00076	2.38e-99	-	-	-	-	-	-	-	-
HMDFGJHI_00077	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HMDFGJHI_00078	5.67e-179	-	-	-	-	-	-	-	-
HMDFGJHI_00079	4.07e-05	-	-	-	-	-	-	-	-
HMDFGJHI_00080	5.9e-186	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HMDFGJHI_00081	1.67e-54	-	-	-	-	-	-	-	-
HMDFGJHI_00082	7.41e-167	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMDFGJHI_00083	8.38e-193	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HMDFGJHI_00084	6.15e-234	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HMDFGJHI_00085	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HMDFGJHI_00086	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HMDFGJHI_00087	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HMDFGJHI_00088	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HMDFGJHI_00089	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HMDFGJHI_00090	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMDFGJHI_00091	6.38e-194	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HMDFGJHI_00092	6.09e-228	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HMDFGJHI_00094	1.87e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMDFGJHI_00095	8.33e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HMDFGJHI_00096	7.15e-148	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HMDFGJHI_00097	9.14e-265	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HMDFGJHI_00098	7.45e-178	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HMDFGJHI_00099	0.0	-	-	-	L	-	-	-	HIRAN domain
HMDFGJHI_00100	1.24e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HMDFGJHI_00101	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HMDFGJHI_00102	3.8e-161	-	-	-	-	-	-	-	-
HMDFGJHI_00103	5.08e-192	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HMDFGJHI_00104	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HMDFGJHI_00105	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HMDFGJHI_00106	5.99e-143	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HMDFGJHI_00107	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_00108	2.31e-95	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HMDFGJHI_00109	2.14e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HMDFGJHI_00110	7.39e-87	-	-	-	K	-	-	-	LytTr DNA-binding domain
HMDFGJHI_00111	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HMDFGJHI_00112	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMDFGJHI_00113	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HMDFGJHI_00115	1.34e-198	morA	-	-	S	-	-	-	reductase
HMDFGJHI_00116	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HMDFGJHI_00117	4.54e-105	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HMDFGJHI_00118	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HMDFGJHI_00119	2.41e-125	-	-	-	-	-	-	-	-
HMDFGJHI_00120	0.0	-	-	-	-	-	-	-	-
HMDFGJHI_00121	7.26e-265	-	-	-	C	-	-	-	Oxidoreductase
HMDFGJHI_00122	7.71e-192	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HMDFGJHI_00123	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_00124	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HMDFGJHI_00125	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HMDFGJHI_00126	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HMDFGJHI_00127	3.14e-182	-	-	-	-	-	-	-	-
HMDFGJHI_00128	1.29e-190	-	-	-	-	-	-	-	-
HMDFGJHI_00129	3.37e-115	-	-	-	-	-	-	-	-
HMDFGJHI_00130	7.14e-185	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HMDFGJHI_00131	4.24e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMDFGJHI_00132	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HMDFGJHI_00133	1.09e-148	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HMDFGJHI_00134	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HMDFGJHI_00135	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HMDFGJHI_00137	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_00138	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HMDFGJHI_00139	3.88e-239	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HMDFGJHI_00140	2.75e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HMDFGJHI_00141	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HMDFGJHI_00142	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMDFGJHI_00143	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HMDFGJHI_00144	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HMDFGJHI_00145	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HMDFGJHI_00146	4.69e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMDFGJHI_00147	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMDFGJHI_00148	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMDFGJHI_00149	1.01e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HMDFGJHI_00150	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HMDFGJHI_00151	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMDFGJHI_00152	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HMDFGJHI_00153	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HMDFGJHI_00154	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HMDFGJHI_00155	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HMDFGJHI_00156	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HMDFGJHI_00157	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMDFGJHI_00158	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HMDFGJHI_00159	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HMDFGJHI_00160	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMDFGJHI_00161	9.51e-210	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HMDFGJHI_00162	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HMDFGJHI_00163	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMDFGJHI_00164	5.99e-213	mleR	-	-	K	-	-	-	LysR substrate binding domain
HMDFGJHI_00165	0.0	-	-	-	M	-	-	-	domain protein
HMDFGJHI_00167	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HMDFGJHI_00168	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMDFGJHI_00169	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMDFGJHI_00170	3.22e-103	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HMDFGJHI_00171	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMDFGJHI_00172	7.18e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMDFGJHI_00173	2.73e-147	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HMDFGJHI_00174	1.44e-228	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HMDFGJHI_00175	6.33e-46	-	-	-	-	-	-	-	-
HMDFGJHI_00176	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HMDFGJHI_00177	6.48e-210	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HMDFGJHI_00178	3.69e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMDFGJHI_00179	3.81e-18	-	-	-	-	-	-	-	-
HMDFGJHI_00180	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMDFGJHI_00181	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMDFGJHI_00182	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HMDFGJHI_00183	8.68e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HMDFGJHI_00184	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HMDFGJHI_00185	2.02e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HMDFGJHI_00186	3.79e-113	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HMDFGJHI_00187	2.16e-201	dkgB	-	-	S	-	-	-	reductase
HMDFGJHI_00188	3.68e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMDFGJHI_00189	1.2e-91	-	-	-	-	-	-	-	-
HMDFGJHI_00190	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMDFGJHI_00192	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HMDFGJHI_00193	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMDFGJHI_00194	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HMDFGJHI_00195	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDFGJHI_00196	1.06e-281	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HMDFGJHI_00197	2.43e-111	-	-	-	-	-	-	-	-
HMDFGJHI_00198	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HMDFGJHI_00199	5.92e-67	-	-	-	-	-	-	-	-
HMDFGJHI_00200	1.22e-125	-	-	-	-	-	-	-	-
HMDFGJHI_00201	2.98e-90	-	-	-	-	-	-	-	-
HMDFGJHI_00202	1.2e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HMDFGJHI_00203	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HMDFGJHI_00204	1.82e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HMDFGJHI_00205	7.42e-125	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HMDFGJHI_00206	1.42e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HMDFGJHI_00207	1.3e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HMDFGJHI_00208	3.89e-202	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HMDFGJHI_00209	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HMDFGJHI_00210	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HMDFGJHI_00211	6.35e-56	-	-	-	-	-	-	-	-
HMDFGJHI_00212	1.38e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HMDFGJHI_00213	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMDFGJHI_00214	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMDFGJHI_00215	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HMDFGJHI_00216	2.13e-184	-	-	-	-	-	-	-	-
HMDFGJHI_00217	1.78e-128	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HMDFGJHI_00218	7.84e-92	-	-	-	-	-	-	-	-
HMDFGJHI_00219	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_00220	5.2e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_00221	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HMDFGJHI_00222	1.15e-152	-	-	-	-	-	-	-	-
HMDFGJHI_00223	2.92e-57	-	-	-	-	-	-	-	-
HMDFGJHI_00224	1.55e-55	-	-	-	-	-	-	-	-
HMDFGJHI_00225	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HMDFGJHI_00226	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMDFGJHI_00227	1.82e-316	hpk2	-	-	T	-	-	-	Histidine kinase
HMDFGJHI_00228	3.28e-166	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HMDFGJHI_00229	2.42e-65	-	-	-	-	-	-	-	-
HMDFGJHI_00230	1.13e-166	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HMDFGJHI_00231	1.81e-308	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDFGJHI_00232	6.77e-75	-	-	-	-	-	-	-	-
HMDFGJHI_00233	2.87e-56	-	-	-	-	-	-	-	-
HMDFGJHI_00234	1.76e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HMDFGJHI_00235	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HMDFGJHI_00236	1.49e-63	-	-	-	-	-	-	-	-
HMDFGJHI_00237	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HMDFGJHI_00238	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HMDFGJHI_00239	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HMDFGJHI_00240	8.31e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HMDFGJHI_00241	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HMDFGJHI_00242	1.84e-295	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HMDFGJHI_00243	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HMDFGJHI_00244	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HMDFGJHI_00245	4.75e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMDFGJHI_00246	7.98e-80	-	-	-	M	-	-	-	Lysin motif
HMDFGJHI_00247	1.43e-82	-	-	-	M	-	-	-	LysM domain protein
HMDFGJHI_00248	1.41e-86	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HMDFGJHI_00249	2.59e-228	-	-	-	-	-	-	-	-
HMDFGJHI_00250	2.8e-169	-	-	-	-	-	-	-	-
HMDFGJHI_00251	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HMDFGJHI_00252	4.8e-74	-	-	-	-	-	-	-	-
HMDFGJHI_00253	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMDFGJHI_00254	7.61e-102	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HMDFGJHI_00255	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_00256	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HMDFGJHI_00257	6.01e-51	-	-	-	-	-	-	-	-
HMDFGJHI_00259	1.04e-35	-	-	-	-	-	-	-	-
HMDFGJHI_00260	9.25e-32	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
HMDFGJHI_00261	4.36e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMDFGJHI_00262	5.58e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMDFGJHI_00263	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMDFGJHI_00264	5.09e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMDFGJHI_00265	4.3e-124	-	-	-	K	-	-	-	Cupin domain
HMDFGJHI_00266	8.08e-110	-	-	-	S	-	-	-	ASCH
HMDFGJHI_00267	1.88e-111	-	-	-	K	-	-	-	GNAT family
HMDFGJHI_00268	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
HMDFGJHI_00269	2.06e-30	-	-	-	-	-	-	-	-
HMDFGJHI_00270	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HMDFGJHI_00271	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMDFGJHI_00272	3.09e-243	-	-	-	-	-	-	-	-
HMDFGJHI_00273	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HMDFGJHI_00274	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HMDFGJHI_00276	2.36e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HMDFGJHI_00277	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HMDFGJHI_00278	7.28e-42	-	-	-	-	-	-	-	-
HMDFGJHI_00279	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HMDFGJHI_00280	6.4e-54	-	-	-	-	-	-	-	-
HMDFGJHI_00281	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HMDFGJHI_00282	1.49e-227	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMDFGJHI_00283	1.45e-79	-	-	-	S	-	-	-	CHY zinc finger
HMDFGJHI_00284	1.06e-143	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HMDFGJHI_00285	7.98e-158	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMDFGJHI_00286	4.45e-116	metP_2	-	-	U	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMDFGJHI_00287	1.14e-186	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMDFGJHI_00288	2.25e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HMDFGJHI_00289	9.08e-280	-	-	-	-	-	-	-	-
HMDFGJHI_00290	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HMDFGJHI_00291	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HMDFGJHI_00292	3.93e-59	-	-	-	-	-	-	-	-
HMDFGJHI_00293	2.24e-112	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HMDFGJHI_00294	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HMDFGJHI_00295	4.08e-306	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HMDFGJHI_00296	9e-227	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HMDFGJHI_00297	8.95e-60	-	-	-	-	-	-	-	-
HMDFGJHI_00298	1.05e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HMDFGJHI_00299	7.16e-155	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HMDFGJHI_00300	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HMDFGJHI_00301	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HMDFGJHI_00302	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HMDFGJHI_00303	1.61e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HMDFGJHI_00304	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HMDFGJHI_00305	1.52e-103	-	-	-	-	-	-	-	-
HMDFGJHI_00306	2.43e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMDFGJHI_00307	6.07e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HMDFGJHI_00308	4.01e-206	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMDFGJHI_00309	1.94e-100	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HMDFGJHI_00310	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMDFGJHI_00311	1.1e-229	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_00312	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HMDFGJHI_00313	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMDFGJHI_00314	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HMDFGJHI_00315	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMDFGJHI_00316	0.0	-	-	-	M	-	-	-	domain protein
HMDFGJHI_00317	6.35e-89	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
HMDFGJHI_00318	7.13e-54	-	-	-	-	-	-	-	-
HMDFGJHI_00319	2.85e-53	-	-	-	-	-	-	-	-
HMDFGJHI_00321	3.15e-229	-	-	-	-	-	-	-	-
HMDFGJHI_00322	1.24e-11	-	-	-	S	-	-	-	Immunity protein 22
HMDFGJHI_00323	5.89e-131	-	-	-	S	-	-	-	ankyrin repeats
HMDFGJHI_00324	3.31e-52	-	-	-	-	-	-	-	-
HMDFGJHI_00325	8.53e-28	-	-	-	-	-	-	-	-
HMDFGJHI_00326	4.14e-25	-	-	-	U	-	-	-	nuclease activity
HMDFGJHI_00327	2.05e-90	-	-	-	-	-	-	-	-
HMDFGJHI_00328	1.18e-24	-	-	-	-	-	-	-	-
HMDFGJHI_00329	1.72e-90	-	-	-	S	-	-	-	Immunity protein 63
HMDFGJHI_00330	9.91e-17	-	-	-	L	-	-	-	LXG domain of WXG superfamily
HMDFGJHI_00331	3.47e-54	-	-	-	-	-	-	-	-
HMDFGJHI_00332	4.56e-154	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HMDFGJHI_00333	1.29e-261	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HMDFGJHI_00334	2.3e-185	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HMDFGJHI_00335	2.35e-212	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_00336	8.38e-192	-	-	-	S	-	-	-	hydrolase
HMDFGJHI_00337	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HMDFGJHI_00338	8.8e-265	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMDFGJHI_00340	1.15e-43	-	-	-	-	-	-	-	-
HMDFGJHI_00341	6.24e-25	plnR	-	-	-	-	-	-	-
HMDFGJHI_00342	9.76e-153	-	-	-	-	-	-	-	-
HMDFGJHI_00343	3.29e-32	plnK	-	-	-	-	-	-	-
HMDFGJHI_00344	8.53e-34	plnJ	-	-	-	-	-	-	-
HMDFGJHI_00345	4.08e-39	-	-	-	-	-	-	-	-
HMDFGJHI_00347	3.77e-289	-	-	-	M	-	-	-	Glycosyl transferase family 2
HMDFGJHI_00348	2.08e-160	plnP	-	-	S	-	-	-	CAAX protease self-immunity
HMDFGJHI_00349	1.22e-36	-	-	-	-	-	-	-	-
HMDFGJHI_00350	1.9e-25	plnA	-	-	-	-	-	-	-
HMDFGJHI_00351	3.92e-290	plnB	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HMDFGJHI_00352	5.61e-169	sppR	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HMDFGJHI_00353	3.38e-170	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HMDFGJHI_00354	1.64e-166	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMDFGJHI_00355	7.89e-31	plnF	-	-	-	-	-	-	-
HMDFGJHI_00356	8.82e-32	-	-	-	-	-	-	-	-
HMDFGJHI_00357	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMDFGJHI_00358	6.08e-309	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HMDFGJHI_00359	1.24e-138	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMDFGJHI_00360	1.89e-150	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMDFGJHI_00361	7.55e-143	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HMDFGJHI_00362	1.36e-146	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMDFGJHI_00363	3.12e-48	-	-	-	S	ko:K07334	-	ko00000,ko02048	RelE-like toxin of type II toxin-antitoxin system HigB
HMDFGJHI_00364	4.23e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
HMDFGJHI_00365	0.0	-	-	-	L	-	-	-	DNA helicase
HMDFGJHI_00366	3.54e-182	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HMDFGJHI_00367	8.19e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HMDFGJHI_00368	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HMDFGJHI_00369	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDFGJHI_00370	9.68e-34	-	-	-	-	-	-	-	-
HMDFGJHI_00371	3.55e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HMDFGJHI_00372	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDFGJHI_00373	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMDFGJHI_00374	6.97e-209	-	-	-	GK	-	-	-	ROK family
HMDFGJHI_00375	3.97e-174	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HMDFGJHI_00376	4.48e-241	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMDFGJHI_00377	1.23e-262	-	-	-	-	-	-	-	-
HMDFGJHI_00378	5.08e-194	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMDFGJHI_00379	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HMDFGJHI_00380	5.59e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HMDFGJHI_00381	4.65e-229	-	-	-	-	-	-	-	-
HMDFGJHI_00382	2.14e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HMDFGJHI_00383	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HMDFGJHI_00384	6.59e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HMDFGJHI_00385	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMDFGJHI_00386	3.91e-268	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HMDFGJHI_00387	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HMDFGJHI_00388	1.87e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMDFGJHI_00389	7.17e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMDFGJHI_00390	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HMDFGJHI_00391	7.25e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMDFGJHI_00392	1.56e-229	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HMDFGJHI_00393	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HMDFGJHI_00394	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HMDFGJHI_00395	2.4e-56	-	-	-	S	-	-	-	ankyrin repeats
HMDFGJHI_00396	5.3e-49	-	-	-	-	-	-	-	-
HMDFGJHI_00397	2.79e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HMDFGJHI_00398	3.28e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMDFGJHI_00399	1.15e-195	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HMDFGJHI_00400	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMDFGJHI_00401	1.82e-232	-	-	-	S	-	-	-	DUF218 domain
HMDFGJHI_00402	7.12e-178	-	-	-	-	-	-	-	-
HMDFGJHI_00403	1.19e-190	yxeH	-	-	S	-	-	-	hydrolase
HMDFGJHI_00404	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HMDFGJHI_00405	8.97e-200	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HMDFGJHI_00406	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HMDFGJHI_00407	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMDFGJHI_00408	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMDFGJHI_00409	2.38e-311	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMDFGJHI_00410	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HMDFGJHI_00411	1.52e-158	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HMDFGJHI_00412	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HMDFGJHI_00413	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HMDFGJHI_00414	4.01e-36	-	-	-	-	-	-	-	-
HMDFGJHI_00415	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMDFGJHI_00416	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HMDFGJHI_00417	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HMDFGJHI_00418	2.57e-274	-	-	-	J	-	-	-	translation release factor activity
HMDFGJHI_00419	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HMDFGJHI_00420	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HMDFGJHI_00421	5.58e-195	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HMDFGJHI_00422	1.84e-189	-	-	-	-	-	-	-	-
HMDFGJHI_00423	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMDFGJHI_00424	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMDFGJHI_00425	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMDFGJHI_00426	5e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMDFGJHI_00427	4.28e-84	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HMDFGJHI_00428	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HMDFGJHI_00429	1.38e-53	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HMDFGJHI_00430	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HMDFGJHI_00431	9.1e-261	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HMDFGJHI_00432	1.04e-243	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMDFGJHI_00433	3.39e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMDFGJHI_00434	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HMDFGJHI_00435	4.66e-278	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HMDFGJHI_00436	2.63e-241	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMDFGJHI_00437	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HMDFGJHI_00438	1.4e-147	-	-	-	S	-	-	-	(CBS) domain
HMDFGJHI_00439	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HMDFGJHI_00440	1.13e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HMDFGJHI_00441	8.29e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMDFGJHI_00442	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMDFGJHI_00443	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HMDFGJHI_00444	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HMDFGJHI_00446	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HMDFGJHI_00447	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HMDFGJHI_00448	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMDFGJHI_00449	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HMDFGJHI_00450	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMDFGJHI_00451	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMDFGJHI_00452	2.53e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMDFGJHI_00453	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HMDFGJHI_00458	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HMDFGJHI_00459	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HMDFGJHI_00463	2.12e-64	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HMDFGJHI_00464	2.78e-71	-	-	-	S	-	-	-	Cupin domain
HMDFGJHI_00465	1.53e-212	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HMDFGJHI_00466	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
HMDFGJHI_00467	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HMDFGJHI_00468	2.65e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMDFGJHI_00469	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMDFGJHI_00470	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HMDFGJHI_00471	3.99e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HMDFGJHI_00472	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMDFGJHI_00473	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMDFGJHI_00474	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HMDFGJHI_00475	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HMDFGJHI_00476	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HMDFGJHI_00477	7.89e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HMDFGJHI_00478	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HMDFGJHI_00479	8.77e-204	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMDFGJHI_00483	4.34e-31	-	-	-	-	-	-	-	-
HMDFGJHI_00485	5.27e-210	-	-	-	G	-	-	-	Peptidase_C39 like family
HMDFGJHI_00486	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMDFGJHI_00487	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HMDFGJHI_00488	1.87e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HMDFGJHI_00489	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HMDFGJHI_00490	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HMDFGJHI_00491	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HMDFGJHI_00492	1.83e-112	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMDFGJHI_00493	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMDFGJHI_00494	3.77e-84	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HMDFGJHI_00495	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HMDFGJHI_00496	1.49e-183	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMDFGJHI_00497	5e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HMDFGJHI_00498	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HMDFGJHI_00499	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HMDFGJHI_00500	4.25e-227	-	-	-	EG	-	-	-	EamA-like transporter family
HMDFGJHI_00501	1.11e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMDFGJHI_00502	1.12e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HMDFGJHI_00503	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HMDFGJHI_00504	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMDFGJHI_00505	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HMDFGJHI_00506	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HMDFGJHI_00507	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMDFGJHI_00508	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HMDFGJHI_00509	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMDFGJHI_00510	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HMDFGJHI_00511	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMDFGJHI_00512	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMDFGJHI_00513	1.75e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HMDFGJHI_00514	1.31e-129	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HMDFGJHI_00515	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HMDFGJHI_00516	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMDFGJHI_00517	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HMDFGJHI_00518	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMDFGJHI_00519	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMDFGJHI_00520	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMDFGJHI_00521	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMDFGJHI_00522	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMDFGJHI_00523	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HMDFGJHI_00524	1.78e-88	-	-	-	L	-	-	-	nuclease
HMDFGJHI_00525	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMDFGJHI_00526	5.03e-50	-	-	-	K	-	-	-	Helix-turn-helix domain
HMDFGJHI_00527	5.82e-141	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HMDFGJHI_00528	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMDFGJHI_00529	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMDFGJHI_00530	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HMDFGJHI_00531	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HMDFGJHI_00532	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMDFGJHI_00533	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMDFGJHI_00534	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMDFGJHI_00535	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMDFGJHI_00536	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HMDFGJHI_00537	2.22e-153	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMDFGJHI_00538	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HMDFGJHI_00539	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HMDFGJHI_00540	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HMDFGJHI_00541	2.64e-213	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMDFGJHI_00542	2.61e-190	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HMDFGJHI_00543	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HMDFGJHI_00544	2.18e-269	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HMDFGJHI_00545	1.62e-186	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HMDFGJHI_00546	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMDFGJHI_00547	5.35e-177	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HMDFGJHI_00548	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HMDFGJHI_00549	3.46e-242	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HMDFGJHI_00550	4.43e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HMDFGJHI_00551	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HMDFGJHI_00552	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HMDFGJHI_00553	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMDFGJHI_00554	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HMDFGJHI_00555	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMDFGJHI_00556	1.68e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMDFGJHI_00557	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMDFGJHI_00558	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMDFGJHI_00559	0.0	ydaO	-	-	E	-	-	-	amino acid
HMDFGJHI_00560	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HMDFGJHI_00561	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HMDFGJHI_00562	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HMDFGJHI_00563	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HMDFGJHI_00564	3.43e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HMDFGJHI_00565	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMDFGJHI_00566	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMDFGJHI_00567	8.03e-256	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMDFGJHI_00568	1.28e-276	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HMDFGJHI_00569	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HMDFGJHI_00570	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMDFGJHI_00571	6.91e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HMDFGJHI_00572	2.22e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HMDFGJHI_00573	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HMDFGJHI_00574	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMDFGJHI_00575	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMDFGJHI_00576	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HMDFGJHI_00577	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HMDFGJHI_00578	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HMDFGJHI_00579	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMDFGJHI_00580	1.04e-211	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMDFGJHI_00581	2.82e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HMDFGJHI_00582	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HMDFGJHI_00583	6.93e-112	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HMDFGJHI_00584	0.0	nox	-	-	C	-	-	-	NADH oxidase
HMDFGJHI_00585	7.45e-206	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HMDFGJHI_00586	2.45e-310	-	-	-	-	-	-	-	-
HMDFGJHI_00587	3.39e-256	-	-	-	S	-	-	-	Protein conserved in bacteria
HMDFGJHI_00588	2.74e-277	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HMDFGJHI_00589	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HMDFGJHI_00590	6.49e-171	-	-	-	T	-	-	-	diguanylate cyclase activity
HMDFGJHI_00591	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMDFGJHI_00592	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HMDFGJHI_00593	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HMDFGJHI_00594	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMDFGJHI_00595	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HMDFGJHI_00596	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HMDFGJHI_00597	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HMDFGJHI_00598	3.08e-267	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HMDFGJHI_00599	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HMDFGJHI_00600	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMDFGJHI_00601	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMDFGJHI_00602	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMDFGJHI_00603	4.34e-301	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMDFGJHI_00604	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HMDFGJHI_00605	8.62e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HMDFGJHI_00606	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HMDFGJHI_00607	4.56e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HMDFGJHI_00608	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HMDFGJHI_00609	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMDFGJHI_00610	1.55e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMDFGJHI_00611	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMDFGJHI_00613	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HMDFGJHI_00614	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HMDFGJHI_00615	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMDFGJHI_00616	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HMDFGJHI_00617	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMDFGJHI_00618	9.4e-317	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMDFGJHI_00619	5.11e-171	-	-	-	-	-	-	-	-
HMDFGJHI_00620	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HMDFGJHI_00621	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HMDFGJHI_00622	6.62e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HMDFGJHI_00623	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMDFGJHI_00624	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMDFGJHI_00625	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HMDFGJHI_00626	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMDFGJHI_00627	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_00628	7.98e-137	-	-	-	-	-	-	-	-
HMDFGJHI_00629	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMDFGJHI_00630	5.71e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMDFGJHI_00631	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HMDFGJHI_00632	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HMDFGJHI_00633	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HMDFGJHI_00634	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HMDFGJHI_00635	1.03e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HMDFGJHI_00636	1.71e-210	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HMDFGJHI_00637	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HMDFGJHI_00638	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HMDFGJHI_00639	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMDFGJHI_00640	6.9e-157	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HMDFGJHI_00641	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMDFGJHI_00642	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HMDFGJHI_00643	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMDFGJHI_00644	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMDFGJHI_00645	3.15e-158	-	-	-	T	-	-	-	EAL domain
HMDFGJHI_00646	1.33e-188	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HMDFGJHI_00647	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_00648	2.07e-263	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HMDFGJHI_00649	3.38e-70	-	-	-	-	-	-	-	-
HMDFGJHI_00650	2.49e-95	-	-	-	-	-	-	-	-
HMDFGJHI_00651	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HMDFGJHI_00652	1.73e-178	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HMDFGJHI_00653	2.09e-42	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HMDFGJHI_00654	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMDFGJHI_00655	4.13e-182	-	-	-	-	-	-	-	-
HMDFGJHI_00657	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HMDFGJHI_00658	3.88e-46	-	-	-	-	-	-	-	-
HMDFGJHI_00659	2.08e-117	-	-	-	V	-	-	-	VanZ like family
HMDFGJHI_00660	1.06e-314	-	-	-	EGP	-	-	-	Major Facilitator
HMDFGJHI_00661	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HMDFGJHI_00662	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HMDFGJHI_00663	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HMDFGJHI_00664	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HMDFGJHI_00665	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_00666	1.36e-27	-	-	-	-	-	-	-	-
HMDFGJHI_00667	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HMDFGJHI_00668	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMDFGJHI_00669	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HMDFGJHI_00670	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMDFGJHI_00671	6.37e-232	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HMDFGJHI_00672	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMDFGJHI_00673	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HMDFGJHI_00674	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMDFGJHI_00675	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
HMDFGJHI_00676	1.09e-60	-	-	-	-	-	-	-	-
HMDFGJHI_00677	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HMDFGJHI_00678	6.12e-115	-	-	-	-	-	-	-	-
HMDFGJHI_00679	5.24e-191	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HMDFGJHI_00680	1.24e-94	-	-	-	F	-	-	-	Nudix hydrolase
HMDFGJHI_00681	1.48e-27	-	-	-	-	-	-	-	-
HMDFGJHI_00682	6.02e-135	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HMDFGJHI_00683	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HMDFGJHI_00684	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HMDFGJHI_00685	1.01e-188	-	-	-	-	-	-	-	-
HMDFGJHI_00686	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HMDFGJHI_00687	3.21e-268	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HMDFGJHI_00688	1.03e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMDFGJHI_00689	1.28e-54	-	-	-	-	-	-	-	-
HMDFGJHI_00691	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_00692	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HMDFGJHI_00693	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMDFGJHI_00694	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMDFGJHI_00695	2.99e-109	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMDFGJHI_00696	1.34e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HMDFGJHI_00697	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HMDFGJHI_00698	9.06e-182	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HMDFGJHI_00699	9.38e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HMDFGJHI_00700	2.98e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMDFGJHI_00701	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HMDFGJHI_00702	3.08e-93	-	-	-	K	-	-	-	MarR family
HMDFGJHI_00703	9.23e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMDFGJHI_00704	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HMDFGJHI_00705	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_00706	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMDFGJHI_00707	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
HMDFGJHI_00708	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HMDFGJHI_00709	1.61e-36	-	-	-	-	-	-	-	-
HMDFGJHI_00710	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HMDFGJHI_00711	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HMDFGJHI_00712	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HMDFGJHI_00713	1.39e-225	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HMDFGJHI_00714	6.4e-143	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HMDFGJHI_00715	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HMDFGJHI_00716	1.46e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HMDFGJHI_00717	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HMDFGJHI_00718	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HMDFGJHI_00719	1.08e-71	-	-	-	-	-	-	-	-
HMDFGJHI_00720	5.57e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
HMDFGJHI_00721	0.0	-	-	-	L	-	-	-	AAA domain
HMDFGJHI_00722	5.77e-149	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HMDFGJHI_00723	1.85e-75	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HMDFGJHI_00724	4.73e-302	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HMDFGJHI_00725	2.28e-292	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HMDFGJHI_00726	2.56e-66	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HMDFGJHI_00727	2.45e-120	-	-	-	D	-	-	-	nuclear chromosome segregation
HMDFGJHI_00728	1.85e-110	-	-	-	-	-	-	-	-
HMDFGJHI_00729	9.14e-204	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HMDFGJHI_00730	6.35e-69	-	-	-	-	-	-	-	-
HMDFGJHI_00731	3.61e-61	-	-	-	S	-	-	-	MORN repeat
HMDFGJHI_00732	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HMDFGJHI_00733	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HMDFGJHI_00734	1.95e-116	-	-	-	-	-	-	-	-
HMDFGJHI_00735	5.74e-32	-	-	-	-	-	-	-	-
HMDFGJHI_00736	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HMDFGJHI_00737	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HMDFGJHI_00738	4.76e-191	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HMDFGJHI_00739	2.11e-211	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HMDFGJHI_00740	4.46e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HMDFGJHI_00741	3.1e-131	-	-	-	G	-	-	-	Glycogen debranching enzyme
HMDFGJHI_00742	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HMDFGJHI_00743	0.000211	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HMDFGJHI_00744	4.75e-102	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HMDFGJHI_00745	1.44e-33	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HMDFGJHI_00746	9.97e-108	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HMDFGJHI_00748	2.81e-118	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HMDFGJHI_00749	1.54e-310	-	-	-	M	-	-	-	MucBP domain
HMDFGJHI_00750	2.82e-261	-	-	-	M	-	-	-	MucBP domain
HMDFGJHI_00751	1.13e-62	-	-	-	M	-	-	-	MucBP domain
HMDFGJHI_00752	1.42e-08	-	-	-	-	-	-	-	-
HMDFGJHI_00753	1.27e-115	-	-	-	S	-	-	-	AAA domain
HMDFGJHI_00754	7.45e-180	-	-	-	K	-	-	-	sequence-specific DNA binding
HMDFGJHI_00755	1.09e-123	-	-	-	K	-	-	-	Helix-turn-helix domain
HMDFGJHI_00756	1.6e-219	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_00757	0.0	-	-	-	C	-	-	-	FMN_bind
HMDFGJHI_00759	3.54e-105	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_00760	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HMDFGJHI_00761	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HMDFGJHI_00762	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HMDFGJHI_00763	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HMDFGJHI_00764	7.64e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HMDFGJHI_00765	1.56e-55	-	-	-	-	-	-	-	-
HMDFGJHI_00766	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HMDFGJHI_00767	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HMDFGJHI_00768	1.65e-209	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HMDFGJHI_00769	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMDFGJHI_00770	1.44e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HMDFGJHI_00771	3.91e-244	-	-	-	-	-	-	-	-
HMDFGJHI_00772	3.42e-280	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HMDFGJHI_00773	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HMDFGJHI_00774	3.36e-132	-	-	-	K	-	-	-	FR47-like protein
HMDFGJHI_00775	1.19e-153	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HMDFGJHI_00776	3.33e-64	-	-	-	-	-	-	-	-
HMDFGJHI_00777	3.48e-245	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMDFGJHI_00778	0.0	xylP2	-	-	G	-	-	-	symporter
HMDFGJHI_00779	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMDFGJHI_00780	1.99e-280	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HMDFGJHI_00781	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HMDFGJHI_00782	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HMDFGJHI_00783	9.62e-154	azlC	-	-	E	-	-	-	branched-chain amino acid
HMDFGJHI_00784	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HMDFGJHI_00785	3.29e-174	-	-	-	-	-	-	-	-
HMDFGJHI_00786	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HMDFGJHI_00787	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HMDFGJHI_00788	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HMDFGJHI_00789	1.36e-77	-	-	-	-	-	-	-	-
HMDFGJHI_00790	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HMDFGJHI_00791	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HMDFGJHI_00792	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HMDFGJHI_00793	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HMDFGJHI_00794	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HMDFGJHI_00795	2.05e-153	-	-	-	I	-	-	-	phosphatase
HMDFGJHI_00796	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMDFGJHI_00797	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HMDFGJHI_00798	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_00799	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HMDFGJHI_00800	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HMDFGJHI_00801	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HMDFGJHI_00802	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HMDFGJHI_00803	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMDFGJHI_00811	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HMDFGJHI_00812	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMDFGJHI_00813	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_00814	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMDFGJHI_00815	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMDFGJHI_00816	8.58e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HMDFGJHI_00817	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMDFGJHI_00818	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMDFGJHI_00819	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMDFGJHI_00820	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HMDFGJHI_00821	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMDFGJHI_00822	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HMDFGJHI_00823	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMDFGJHI_00824	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMDFGJHI_00825	1.07e-61	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMDFGJHI_00826	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMDFGJHI_00827	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMDFGJHI_00828	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMDFGJHI_00829	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HMDFGJHI_00830	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMDFGJHI_00831	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMDFGJHI_00832	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMDFGJHI_00833	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMDFGJHI_00834	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMDFGJHI_00835	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMDFGJHI_00836	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMDFGJHI_00837	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMDFGJHI_00838	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HMDFGJHI_00839	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HMDFGJHI_00840	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMDFGJHI_00841	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMDFGJHI_00842	1.19e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMDFGJHI_00843	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMDFGJHI_00844	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMDFGJHI_00845	1.8e-219	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMDFGJHI_00846	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HMDFGJHI_00847	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HMDFGJHI_00848	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HMDFGJHI_00849	5.37e-112	-	-	-	S	-	-	-	NusG domain II
HMDFGJHI_00850	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HMDFGJHI_00851	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HMDFGJHI_00852	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMDFGJHI_00853	3.42e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMDFGJHI_00854	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMDFGJHI_00855	5.86e-185	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMDFGJHI_00856	7.21e-193	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMDFGJHI_00857	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMDFGJHI_00858	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HMDFGJHI_00859	8.51e-210	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HMDFGJHI_00860	5.79e-234	-	-	-	S	-	-	-	Membrane
HMDFGJHI_00861	1.35e-261	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HMDFGJHI_00862	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMDFGJHI_00863	6.45e-209	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMDFGJHI_00864	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HMDFGJHI_00865	5.2e-253	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HMDFGJHI_00866	4.93e-275	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HMDFGJHI_00867	3.05e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HMDFGJHI_00868	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HMDFGJHI_00869	5.21e-226	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HMDFGJHI_00870	1.28e-253	-	-	-	K	-	-	-	Helix-turn-helix domain
HMDFGJHI_00871	1.57e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HMDFGJHI_00872	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HMDFGJHI_00873	7.15e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HMDFGJHI_00874	5.19e-223	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HMDFGJHI_00875	1.18e-66	-	-	-	-	-	-	-	-
HMDFGJHI_00876	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HMDFGJHI_00877	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HMDFGJHI_00878	7.14e-229	citR	-	-	K	-	-	-	sugar-binding domain protein
HMDFGJHI_00879	1.92e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HMDFGJHI_00880	5.31e-242	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HMDFGJHI_00881	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HMDFGJHI_00882	3.32e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HMDFGJHI_00883	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HMDFGJHI_00884	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMDFGJHI_00885	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HMDFGJHI_00886	1.98e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HMDFGJHI_00887	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HMDFGJHI_00888	2.65e-214	mleR	-	-	K	-	-	-	LysR family
HMDFGJHI_00889	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HMDFGJHI_00890	9.09e-213	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HMDFGJHI_00891	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HMDFGJHI_00892	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HMDFGJHI_00893	6.07e-33	-	-	-	-	-	-	-	-
HMDFGJHI_00894	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HMDFGJHI_00895	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HMDFGJHI_00896	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HMDFGJHI_00897	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HMDFGJHI_00898	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HMDFGJHI_00899	5.41e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HMDFGJHI_00900	2.11e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HMDFGJHI_00901	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HMDFGJHI_00902	9.47e-236	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HMDFGJHI_00903	2.8e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HMDFGJHI_00904	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMDFGJHI_00905	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HMDFGJHI_00906	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HMDFGJHI_00907	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HMDFGJHI_00908	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMDFGJHI_00909	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
HMDFGJHI_00910	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMDFGJHI_00911	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMDFGJHI_00912	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMDFGJHI_00913	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HMDFGJHI_00914	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMDFGJHI_00915	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_00916	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HMDFGJHI_00917	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDFGJHI_00918	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMDFGJHI_00919	6.57e-195	gntR	-	-	K	-	-	-	rpiR family
HMDFGJHI_00920	4.68e-187	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HMDFGJHI_00921	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HMDFGJHI_00922	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HMDFGJHI_00923	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HMDFGJHI_00924	9.46e-315	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HMDFGJHI_00926	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HMDFGJHI_00927	5.45e-314	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDFGJHI_00928	1.93e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMDFGJHI_00930	7.62e-97	-	-	-	-	-	-	-	-
HMDFGJHI_00931	2.9e-139	-	-	-	-	-	-	-	-
HMDFGJHI_00932	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HMDFGJHI_00933	1.63e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
HMDFGJHI_00934	4.75e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMDFGJHI_00935	7.42e-202	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HMDFGJHI_00936	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMDFGJHI_00937	1.84e-22	-	-	-	E	-	-	-	Zn peptidase
HMDFGJHI_00938	3.62e-252	cps3H	-	-	-	-	-	-	-
HMDFGJHI_00939	5.67e-257	cps3I	-	-	G	-	-	-	Acyltransferase family
HMDFGJHI_00940	2.94e-190	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HMDFGJHI_00941	5.98e-305	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HMDFGJHI_00942	1.38e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HMDFGJHI_00943	9.02e-70	-	-	-	-	-	-	-	-
HMDFGJHI_00944	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HMDFGJHI_00945	8.39e-38	-	-	-	-	-	-	-	-
HMDFGJHI_00946	4.14e-132	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HMDFGJHI_00947	1.15e-169	-	-	-	-	-	-	-	-
HMDFGJHI_00948	4.1e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HMDFGJHI_00949	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HMDFGJHI_00950	1.94e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
HMDFGJHI_00951	3.97e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HMDFGJHI_00952	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HMDFGJHI_00953	1.67e-166	pbpX	-	-	V	-	-	-	Beta-lactamase
HMDFGJHI_00954	8.52e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HMDFGJHI_00955	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HMDFGJHI_00956	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HMDFGJHI_00957	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HMDFGJHI_00958	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HMDFGJHI_00959	1.22e-218	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HMDFGJHI_00960	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HMDFGJHI_00961	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMDFGJHI_00962	0.0	-	-	-	-	-	-	-	-
HMDFGJHI_00963	2.12e-252	-	-	-	M	-	-	-	MucBP domain
HMDFGJHI_00964	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HMDFGJHI_00965	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HMDFGJHI_00966	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HMDFGJHI_00967	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMDFGJHI_00968	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMDFGJHI_00969	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMDFGJHI_00970	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMDFGJHI_00971	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMDFGJHI_00972	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HMDFGJHI_00973	2.5e-132	-	-	-	L	-	-	-	Integrase
HMDFGJHI_00974	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HMDFGJHI_00975	5.6e-41	-	-	-	-	-	-	-	-
HMDFGJHI_00976	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HMDFGJHI_00977	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMDFGJHI_00978	2.34e-284	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HMDFGJHI_00979	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HMDFGJHI_00980	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMDFGJHI_00981	6.56e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HMDFGJHI_00982	7.9e-289	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HMDFGJHI_00983	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HMDFGJHI_00984	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMDFGJHI_00998	5.4e-118	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HMDFGJHI_00999	3.15e-237	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HMDFGJHI_01000	7.23e-124	-	-	-	-	-	-	-	-
HMDFGJHI_01001	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMDFGJHI_01002	2.52e-201	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HMDFGJHI_01005	3.8e-292	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HMDFGJHI_01006	2.95e-239	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HMDFGJHI_01007	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HMDFGJHI_01008	7.89e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HMDFGJHI_01009	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMDFGJHI_01010	3.21e-155	-	-	-	-	-	-	-	-
HMDFGJHI_01011	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMDFGJHI_01012	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HMDFGJHI_01013	4.39e-305	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HMDFGJHI_01014	7.22e-256	-	-	-	S	-	-	-	Pfam Methyltransferase
HMDFGJHI_01015	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMDFGJHI_01016	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMDFGJHI_01017	9.32e-40	-	-	-	-	-	-	-	-
HMDFGJHI_01018	5.13e-138	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HMDFGJHI_01019	6.19e-162	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HMDFGJHI_01020	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HMDFGJHI_01021	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HMDFGJHI_01022	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HMDFGJHI_01023	9.06e-195	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMDFGJHI_01024	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HMDFGJHI_01025	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HMDFGJHI_01026	1.24e-259	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HMDFGJHI_01027	2.27e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMDFGJHI_01028	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMDFGJHI_01029	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMDFGJHI_01030	5.45e-162	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HMDFGJHI_01031	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HMDFGJHI_01032	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMDFGJHI_01033	7.45e-191	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HMDFGJHI_01034	9.58e-116	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HMDFGJHI_01036	8.55e-163	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HMDFGJHI_01037	1.77e-200	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMDFGJHI_01038	6.05e-225	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HMDFGJHI_01040	9.49e-196	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMDFGJHI_01041	2.12e-84	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMDFGJHI_01042	5.48e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
HMDFGJHI_01043	1.55e-203	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HMDFGJHI_01044	8.04e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMDFGJHI_01045	7.83e-140	-	-	-	-	-	-	-	-
HMDFGJHI_01046	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HMDFGJHI_01047	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HMDFGJHI_01048	5.37e-74	-	-	-	-	-	-	-	-
HMDFGJHI_01049	4.56e-78	-	-	-	-	-	-	-	-
HMDFGJHI_01050	1.06e-146	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMDFGJHI_01051	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HMDFGJHI_01052	8.82e-119	-	-	-	-	-	-	-	-
HMDFGJHI_01053	7.12e-62	-	-	-	-	-	-	-	-
HMDFGJHI_01054	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HMDFGJHI_01057	4.29e-87	-	-	-	-	-	-	-	-
HMDFGJHI_01058	9.03e-16	-	-	-	-	-	-	-	-
HMDFGJHI_01059	3.89e-237	-	-	-	-	-	-	-	-
HMDFGJHI_01060	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HMDFGJHI_01061	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HMDFGJHI_01062	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HMDFGJHI_01063	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMDFGJHI_01064	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HMDFGJHI_01065	8.91e-293	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HMDFGJHI_01066	2.24e-146	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HMDFGJHI_01067	6.91e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HMDFGJHI_01068	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HMDFGJHI_01069	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HMDFGJHI_01070	8.98e-316	dinF	-	-	V	-	-	-	MatE
HMDFGJHI_01071	1.79e-42	-	-	-	-	-	-	-	-
HMDFGJHI_01074	7.02e-103	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HMDFGJHI_01075	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HMDFGJHI_01076	3.81e-105	-	-	-	-	-	-	-	-
HMDFGJHI_01077	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HMDFGJHI_01078	3.61e-137	-	-	-	-	-	-	-	-
HMDFGJHI_01079	2.57e-273	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HMDFGJHI_01080	1.41e-147	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HMDFGJHI_01081	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMDFGJHI_01082	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HMDFGJHI_01083	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HMDFGJHI_01084	2.77e-271	arcT	-	-	E	-	-	-	Aminotransferase
HMDFGJHI_01085	2.41e-101	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HMDFGJHI_01086	2.43e-18	-	-	-	-	-	-	-	-
HMDFGJHI_01087	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HMDFGJHI_01088	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HMDFGJHI_01089	1.05e-294	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HMDFGJHI_01090	0.0	yhaN	-	-	L	-	-	-	AAA domain
HMDFGJHI_01091	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HMDFGJHI_01092	1.58e-277	-	-	-	-	-	-	-	-
HMDFGJHI_01093	1.45e-234	-	-	-	M	-	-	-	Peptidase family S41
HMDFGJHI_01094	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
HMDFGJHI_01095	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HMDFGJHI_01096	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HMDFGJHI_01097	2.57e-128	-	-	-	-	-	-	-	-
HMDFGJHI_01098	2.27e-98	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HMDFGJHI_01099	3.72e-203	-	-	-	T	-	-	-	Histidine kinase
HMDFGJHI_01100	1.73e-134	llrE	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HMDFGJHI_01101	7.93e-79	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
HMDFGJHI_01102	5.57e-168	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HMDFGJHI_01103	1.18e-100	-	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HMDFGJHI_01104	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HMDFGJHI_01105	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMDFGJHI_01106	1.64e-89	-	-	-	S	-	-	-	NUDIX domain
HMDFGJHI_01107	0.0	-	-	-	S	-	-	-	membrane
HMDFGJHI_01108	1.22e-217	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HMDFGJHI_01109	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HMDFGJHI_01110	1.86e-287	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HMDFGJHI_01111	3.01e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HMDFGJHI_01112	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HMDFGJHI_01113	3.39e-138	-	-	-	-	-	-	-	-
HMDFGJHI_01114	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HMDFGJHI_01115	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_01116	5.19e-309	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HMDFGJHI_01117	0.0	-	-	-	-	-	-	-	-
HMDFGJHI_01118	4.75e-80	-	-	-	-	-	-	-	-
HMDFGJHI_01119	3.36e-248	-	-	-	S	-	-	-	Fn3-like domain
HMDFGJHI_01120	1.9e-136	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMDFGJHI_01121	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMDFGJHI_01122	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMDFGJHI_01123	6.76e-73	-	-	-	-	-	-	-	-
HMDFGJHI_01124	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HMDFGJHI_01125	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_01126	9.53e-284	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HMDFGJHI_01127	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HMDFGJHI_01128	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMDFGJHI_01129	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HMDFGJHI_01130	1.45e-145	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMDFGJHI_01131	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HMDFGJHI_01132	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HMDFGJHI_01133	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HMDFGJHI_01134	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HMDFGJHI_01135	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HMDFGJHI_01136	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HMDFGJHI_01137	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HMDFGJHI_01138	6.39e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMDFGJHI_01139	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HMDFGJHI_01140	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HMDFGJHI_01141	6.87e-236	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HMDFGJHI_01142	1.15e-161	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HMDFGJHI_01143	6.56e-211	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMDFGJHI_01144	6.7e-107	-	-	-	C	-	-	-	Flavodoxin
HMDFGJHI_01145	6.26e-92	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HMDFGJHI_01146	7.86e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
HMDFGJHI_01147	3.92e-248	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HMDFGJHI_01148	1.98e-278	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
HMDFGJHI_01149	4.08e-78	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HMDFGJHI_01150	7.79e-203	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HMDFGJHI_01151	4.87e-205	-	-	-	H	-	-	-	geranyltranstransferase activity
HMDFGJHI_01152	4.32e-233	-	-	-	-	-	-	-	-
HMDFGJHI_01153	6.1e-64	-	-	-	-	-	-	-	-
HMDFGJHI_01154	7.76e-152	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HMDFGJHI_01155	8.17e-242	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
HMDFGJHI_01156	1.48e-98	-	2.7.13.3	-	T	ko:K07683,ko:K10851	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	phosphoenolpyruvate-protein phosphotransferase activity
HMDFGJHI_01157	8.84e-52	-	-	-	-	-	-	-	-
HMDFGJHI_01158	5.73e-129	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HMDFGJHI_01159	1.08e-111	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HMDFGJHI_01160	9.62e-116	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HMDFGJHI_01161	1.49e-293	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
HMDFGJHI_01162	9.07e-107	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HMDFGJHI_01163	1.27e-250	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HMDFGJHI_01164	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMDFGJHI_01165	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HMDFGJHI_01166	8.2e-127	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	Nitrate reductase delta subunit
HMDFGJHI_01167	2.69e-158	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
HMDFGJHI_01168	8.63e-226	-	-	-	-	-	-	-	-
HMDFGJHI_01169	1.8e-96	-	-	-	-	-	-	-	-
HMDFGJHI_01171	5.12e-46	-	-	-	S	-	-	-	Phage Mu protein F like protein
HMDFGJHI_01173	4.45e-58	-	-	-	S	-	-	-	Phage minor structural protein GP20
HMDFGJHI_01174	3.46e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HMDFGJHI_01175	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMDFGJHI_01176	1.85e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMDFGJHI_01177	1.92e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMDFGJHI_01178	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMDFGJHI_01179	3.62e-123	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HMDFGJHI_01180	1.91e-143	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HMDFGJHI_01181	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMDFGJHI_01182	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMDFGJHI_01183	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HMDFGJHI_01184	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMDFGJHI_01185	2.76e-74	-	-	-	-	-	-	-	-
HMDFGJHI_01186	7.03e-307	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HMDFGJHI_01187	4.79e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HMDFGJHI_01188	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HMDFGJHI_01189	6.86e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HMDFGJHI_01190	9.51e-317	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HMDFGJHI_01191	6.32e-114	-	-	-	-	-	-	-	-
HMDFGJHI_01192	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HMDFGJHI_01193	2.57e-274	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HMDFGJHI_01194	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HMDFGJHI_01195	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMDFGJHI_01196	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HMDFGJHI_01197	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMDFGJHI_01198	3.3e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
HMDFGJHI_01199	1.02e-278	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HMDFGJHI_01200	2.12e-126	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HMDFGJHI_01201	7.2e-123	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HMDFGJHI_01202	1.13e-225	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMDFGJHI_01203	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMDFGJHI_01204	2.98e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HMDFGJHI_01205	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HMDFGJHI_01206	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMDFGJHI_01207	1.59e-217	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HMDFGJHI_01208	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HMDFGJHI_01209	5.55e-288	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMDFGJHI_01210	1.77e-122	-	-	-	S	-	-	-	SdpI/YhfL protein family
HMDFGJHI_01211	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMDFGJHI_01212	2.36e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HMDFGJHI_01213	9.01e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMDFGJHI_01214	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HMDFGJHI_01215	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HMDFGJHI_01216	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMDFGJHI_01217	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMDFGJHI_01218	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMDFGJHI_01219	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HMDFGJHI_01220	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMDFGJHI_01221	9.72e-146	-	-	-	S	-	-	-	membrane
HMDFGJHI_01222	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
HMDFGJHI_01223	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HMDFGJHI_01224	0.0	-	-	-	S	-	-	-	membrane
HMDFGJHI_01225	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HMDFGJHI_01226	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HMDFGJHI_01227	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMDFGJHI_01228	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HMDFGJHI_01229	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HMDFGJHI_01230	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HMDFGJHI_01231	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HMDFGJHI_01232	6.68e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HMDFGJHI_01233	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HMDFGJHI_01234	9.07e-178	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HMDFGJHI_01235	1.33e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMDFGJHI_01236	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HMDFGJHI_01237	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HMDFGJHI_01238	5.08e-205	-	-	-	-	-	-	-	-
HMDFGJHI_01239	1.34e-232	-	-	-	-	-	-	-	-
HMDFGJHI_01240	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
HMDFGJHI_01241	3.11e-73	-	-	-	-	-	-	-	-
HMDFGJHI_01242	2.97e-41	-	-	-	-	-	-	-	-
HMDFGJHI_01245	9.81e-27	-	-	-	-	-	-	-	-
HMDFGJHI_01246	4.04e-125	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_01247	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HMDFGJHI_01248	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HMDFGJHI_01249	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HMDFGJHI_01250	2.46e-248	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HMDFGJHI_01251	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMDFGJHI_01252	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HMDFGJHI_01253	4.86e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMDFGJHI_01254	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMDFGJHI_01255	2.81e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMDFGJHI_01256	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMDFGJHI_01257	6.68e-206	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HMDFGJHI_01258	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HMDFGJHI_01259	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HMDFGJHI_01260	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HMDFGJHI_01261	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_01262	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMDFGJHI_01263	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMDFGJHI_01264	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMDFGJHI_01265	3.51e-74	-	-	-	-	-	-	-	-
HMDFGJHI_01266	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HMDFGJHI_01267	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMDFGJHI_01268	5.04e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMDFGJHI_01269	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMDFGJHI_01270	5.2e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMDFGJHI_01271	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMDFGJHI_01272	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HMDFGJHI_01273	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HMDFGJHI_01274	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMDFGJHI_01275	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HMDFGJHI_01276	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HMDFGJHI_01277	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HMDFGJHI_01278	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HMDFGJHI_01279	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HMDFGJHI_01280	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMDFGJHI_01281	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMDFGJHI_01282	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMDFGJHI_01283	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMDFGJHI_01284	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HMDFGJHI_01285	1.1e-297	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMDFGJHI_01286	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMDFGJHI_01287	9.38e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMDFGJHI_01288	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HMDFGJHI_01289	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HMDFGJHI_01290	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMDFGJHI_01291	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HMDFGJHI_01292	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMDFGJHI_01293	6.21e-68	-	-	-	-	-	-	-	-
HMDFGJHI_01294	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HMDFGJHI_01295	9.06e-112	-	-	-	-	-	-	-	-
HMDFGJHI_01296	1.18e-178	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HMDFGJHI_01297	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HMDFGJHI_01299	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HMDFGJHI_01300	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HMDFGJHI_01301	7.03e-225	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMDFGJHI_01302	1.66e-156	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HMDFGJHI_01303	6.4e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HMDFGJHI_01304	1.79e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMDFGJHI_01305	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMDFGJHI_01306	4.84e-125	entB	-	-	Q	-	-	-	Isochorismatase family
HMDFGJHI_01307	2.9e-226	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HMDFGJHI_01308	2.3e-253	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HMDFGJHI_01309	1.09e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HMDFGJHI_01310	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMDFGJHI_01311	8.02e-230	yneE	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_01312	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMDFGJHI_01313	1.97e-230	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMDFGJHI_01314	8.76e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMDFGJHI_01315	4.93e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HMDFGJHI_01316	1.04e-161	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HMDFGJHI_01317	1.54e-289	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMDFGJHI_01318	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMDFGJHI_01319	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HMDFGJHI_01320	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HMDFGJHI_01321	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMDFGJHI_01322	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HMDFGJHI_01323	7.68e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HMDFGJHI_01324	1.75e-129	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HMDFGJHI_01325	3.64e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HMDFGJHI_01326	3.73e-207	-	-	-	K	-	-	-	LysR substrate binding domain
HMDFGJHI_01327	4.94e-114	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HMDFGJHI_01328	5.36e-247	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMDFGJHI_01329	4.94e-189	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMDFGJHI_01330	1.49e-121	-	-	-	K	-	-	-	transcriptional regulator
HMDFGJHI_01331	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HMDFGJHI_01332	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
HMDFGJHI_01333	1.73e-113	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
HMDFGJHI_01334	2.19e-07	-	-	-	K	-	-	-	transcriptional regulator
HMDFGJHI_01335	1.48e-71	-	-	-	-	-	-	-	-
HMDFGJHI_01336	2.02e-39	-	-	-	-	-	-	-	-
HMDFGJHI_01337	8e-275	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HMDFGJHI_01338	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HMDFGJHI_01339	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HMDFGJHI_01340	2.05e-55	-	-	-	-	-	-	-	-
HMDFGJHI_01341	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HMDFGJHI_01342	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HMDFGJHI_01343	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HMDFGJHI_01344	7.27e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HMDFGJHI_01345	1.51e-48	-	-	-	-	-	-	-	-
HMDFGJHI_01346	5.79e-21	-	-	-	-	-	-	-	-
HMDFGJHI_01347	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HMDFGJHI_01348	4e-40	-	-	-	S	-	-	-	CsbD-like
HMDFGJHI_01349	1.06e-53	-	-	-	-	-	-	-	-
HMDFGJHI_01350	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HMDFGJHI_01351	4.87e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HMDFGJHI_01352	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMDFGJHI_01353	1.04e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HMDFGJHI_01354	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HMDFGJHI_01355	1.25e-66	-	-	-	-	-	-	-	-
HMDFGJHI_01356	3.23e-58	-	-	-	-	-	-	-	-
HMDFGJHI_01357	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMDFGJHI_01358	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HMDFGJHI_01359	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HMDFGJHI_01360	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HMDFGJHI_01361	1.78e-145	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HMDFGJHI_01362	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HMDFGJHI_01363	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HMDFGJHI_01364	3.09e-243	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HMDFGJHI_01365	4.98e-250	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMDFGJHI_01366	1.77e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HMDFGJHI_01367	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HMDFGJHI_01368	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HMDFGJHI_01369	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HMDFGJHI_01370	1.46e-106	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HMDFGJHI_01371	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HMDFGJHI_01372	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HMDFGJHI_01373	1.13e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HMDFGJHI_01375	7.74e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMDFGJHI_01376	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMDFGJHI_01377	1.3e-202	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HMDFGJHI_01378	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
HMDFGJHI_01379	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMDFGJHI_01380	3.28e-233	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMDFGJHI_01381	6.88e-230	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HMDFGJHI_01382	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HMDFGJHI_01383	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMDFGJHI_01384	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HMDFGJHI_01385	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMDFGJHI_01387	4.11e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HMDFGJHI_01389	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HMDFGJHI_01390	7.86e-96	-	-	-	S	-	-	-	SnoaL-like domain
HMDFGJHI_01391	2.65e-228	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HMDFGJHI_01392	1.65e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HMDFGJHI_01393	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMDFGJHI_01394	2.13e-312	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HMDFGJHI_01395	1.44e-234	-	-	-	V	-	-	-	LD-carboxypeptidase
HMDFGJHI_01396	1.99e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HMDFGJHI_01397	3.99e-158	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMDFGJHI_01398	3.22e-247	-	-	-	-	-	-	-	-
HMDFGJHI_01399	1.5e-186	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HMDFGJHI_01400	1.47e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HMDFGJHI_01401	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HMDFGJHI_01402	5.04e-82	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HMDFGJHI_01403	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HMDFGJHI_01404	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMDFGJHI_01405	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HMDFGJHI_01406	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMDFGJHI_01407	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HMDFGJHI_01408	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HMDFGJHI_01409	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HMDFGJHI_01410	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HMDFGJHI_01411	6.38e-92	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HMDFGJHI_01413	2.24e-167	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HMDFGJHI_01414	9.93e-91	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HMDFGJHI_01415	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HMDFGJHI_01416	1.87e-117	-	-	-	F	-	-	-	NUDIX domain
HMDFGJHI_01417	6.19e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_01418	9.28e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMDFGJHI_01419	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HMDFGJHI_01420	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_01421	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HMDFGJHI_01422	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HMDFGJHI_01423	2.9e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HMDFGJHI_01424	2.38e-39	-	-	-	-	-	-	-	-
HMDFGJHI_01425	1.23e-63	-	-	-	-	-	-	-	-
HMDFGJHI_01426	2.32e-189	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HMDFGJHI_01427	4.93e-267	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMDFGJHI_01429	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HMDFGJHI_01430	9.3e-167	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HMDFGJHI_01431	2.59e-177	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HMDFGJHI_01432	1.23e-311	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HMDFGJHI_01433	1.85e-174	-	-	-	-	-	-	-	-
HMDFGJHI_01434	7.79e-78	-	-	-	-	-	-	-	-
HMDFGJHI_01435	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HMDFGJHI_01436	2.63e-287	-	-	-	-	-	-	-	-
HMDFGJHI_01437	7.15e-165	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HMDFGJHI_01438	1.47e-243	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HMDFGJHI_01439	1.66e-249	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMDFGJHI_01440	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMDFGJHI_01441	1.34e-120	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HMDFGJHI_01442	1.6e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMDFGJHI_01443	7.91e-305	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HMDFGJHI_01444	3.81e-64	-	-	-	-	-	-	-	-
HMDFGJHI_01445	4.8e-310	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HMDFGJHI_01446	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMDFGJHI_01447	2.08e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HMDFGJHI_01448	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HMDFGJHI_01449	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMDFGJHI_01450	2.2e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HMDFGJHI_01451	3.91e-216	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HMDFGJHI_01452	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_01453	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMDFGJHI_01454	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMDFGJHI_01455	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMDFGJHI_01456	7.34e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HMDFGJHI_01457	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMDFGJHI_01458	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMDFGJHI_01459	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HMDFGJHI_01460	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMDFGJHI_01461	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMDFGJHI_01462	8.11e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HMDFGJHI_01463	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMDFGJHI_01464	1.07e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMDFGJHI_01466	7.29e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
HMDFGJHI_01467	1.22e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HMDFGJHI_01468	5.85e-159	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HMDFGJHI_01469	5e-252	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HMDFGJHI_01470	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HMDFGJHI_01471	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HMDFGJHI_01472	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HMDFGJHI_01473	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HMDFGJHI_01474	5.91e-209	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HMDFGJHI_01475	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HMDFGJHI_01476	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMDFGJHI_01477	4.04e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMDFGJHI_01478	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_01479	6.46e-109	-	-	-	-	-	-	-	-
HMDFGJHI_01480	3.65e-291	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMDFGJHI_01481	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMDFGJHI_01482	1.29e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HMDFGJHI_01483	5.83e-291	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HMDFGJHI_01484	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMDFGJHI_01485	2.06e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HMDFGJHI_01486	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HMDFGJHI_01487	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HMDFGJHI_01488	5.45e-38	-	-	-	M	-	-	-	Lysin motif
HMDFGJHI_01489	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HMDFGJHI_01490	4.61e-250	-	-	-	S	-	-	-	Helix-turn-helix domain
HMDFGJHI_01491	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMDFGJHI_01492	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HMDFGJHI_01493	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMDFGJHI_01494	5.83e-175	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMDFGJHI_01495	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMDFGJHI_01496	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HMDFGJHI_01497	1.6e-217	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HMDFGJHI_01498	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HMDFGJHI_01499	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HMDFGJHI_01500	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMDFGJHI_01501	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HMDFGJHI_01502	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HMDFGJHI_01503	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMDFGJHI_01504	4.5e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HMDFGJHI_01505	1.61e-251	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMDFGJHI_01506	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HMDFGJHI_01507	2.89e-294	-	-	-	M	-	-	-	O-Antigen ligase
HMDFGJHI_01508	8.81e-166	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HMDFGJHI_01509	1.71e-212	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMDFGJHI_01510	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMDFGJHI_01511	1.8e-261	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMDFGJHI_01512	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HMDFGJHI_01513	1.94e-83	-	-	-	P	-	-	-	Rhodanese Homology Domain
HMDFGJHI_01514	7.43e-119	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMDFGJHI_01515	5.78e-268	-	-	-	-	-	-	-	-
HMDFGJHI_01516	6.09e-281	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HMDFGJHI_01517	1.51e-232	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HMDFGJHI_01518	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HMDFGJHI_01519	1.09e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMDFGJHI_01520	1.54e-305	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HMDFGJHI_01521	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_01522	1.12e-265	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HMDFGJHI_01523	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HMDFGJHI_01524	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HMDFGJHI_01525	5.1e-140	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HMDFGJHI_01526	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HMDFGJHI_01527	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HMDFGJHI_01528	8.09e-146	-	-	-	GM	-	-	-	epimerase
HMDFGJHI_01529	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HMDFGJHI_01530	6.13e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_01531	3.08e-271	-	-	-	S	-	-	-	membrane
HMDFGJHI_01532	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
HMDFGJHI_01533	4.05e-90	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMDFGJHI_01534	6.03e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDFGJHI_01535	7.51e-147	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HMDFGJHI_01536	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HMDFGJHI_01537	3.69e-169	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HMDFGJHI_01538	2.63e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
HMDFGJHI_01539	8.72e-147	-	-	-	GM	-	-	-	NmrA-like family
HMDFGJHI_01540	2.12e-102	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HMDFGJHI_01541	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_01542	2.66e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HMDFGJHI_01544	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HMDFGJHI_01545	1.11e-134	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HMDFGJHI_01546	2.08e-265	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMDFGJHI_01547	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HMDFGJHI_01548	3.43e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMDFGJHI_01550	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HMDFGJHI_01551	3.89e-94	-	-	-	K	-	-	-	MarR family
HMDFGJHI_01552	1.28e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMDFGJHI_01553	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HMDFGJHI_01554	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_01555	2.02e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMDFGJHI_01556	2.48e-252	-	-	-	-	-	-	-	-
HMDFGJHI_01557	5.01e-254	-	-	-	-	-	-	-	-
HMDFGJHI_01558	2.45e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_01559	6.86e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HMDFGJHI_01560	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMDFGJHI_01561	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMDFGJHI_01562	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HMDFGJHI_01563	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HMDFGJHI_01564	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HMDFGJHI_01565	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMDFGJHI_01566	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HMDFGJHI_01567	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMDFGJHI_01568	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HMDFGJHI_01569	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HMDFGJHI_01570	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HMDFGJHI_01571	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HMDFGJHI_01572	3e-165	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HMDFGJHI_01573	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HMDFGJHI_01574	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMDFGJHI_01575	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMDFGJHI_01576	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMDFGJHI_01577	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMDFGJHI_01578	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HMDFGJHI_01579	5.7e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HMDFGJHI_01580	5.35e-213	-	-	-	G	-	-	-	Fructosamine kinase
HMDFGJHI_01581	5.97e-151	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HMDFGJHI_01582	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMDFGJHI_01583	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMDFGJHI_01584	2.56e-76	-	-	-	-	-	-	-	-
HMDFGJHI_01585	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMDFGJHI_01586	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HMDFGJHI_01587	1.11e-147	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HMDFGJHI_01588	4.78e-65	-	-	-	-	-	-	-	-
HMDFGJHI_01589	1.73e-67	-	-	-	-	-	-	-	-
HMDFGJHI_01590	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMDFGJHI_01591	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMDFGJHI_01592	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMDFGJHI_01593	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HMDFGJHI_01594	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMDFGJHI_01595	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HMDFGJHI_01596	4.21e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HMDFGJHI_01597	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMDFGJHI_01598	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HMDFGJHI_01599	1.72e-115	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMDFGJHI_01600	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMDFGJHI_01601	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HMDFGJHI_01602	7.56e-242	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HMDFGJHI_01603	6.29e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMDFGJHI_01604	1.45e-114	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HMDFGJHI_01605	3.1e-248	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HMDFGJHI_01606	6.72e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMDFGJHI_01607	9.84e-123	-	-	-	-	-	-	-	-
HMDFGJHI_01608	2.21e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMDFGJHI_01609	0.0	-	-	-	G	-	-	-	Major Facilitator
HMDFGJHI_01610	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMDFGJHI_01611	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMDFGJHI_01612	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HMDFGJHI_01613	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HMDFGJHI_01614	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HMDFGJHI_01615	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HMDFGJHI_01616	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMDFGJHI_01617	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMDFGJHI_01618	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HMDFGJHI_01619	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HMDFGJHI_01620	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMDFGJHI_01621	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMDFGJHI_01622	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HMDFGJHI_01623	2.67e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMDFGJHI_01624	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HMDFGJHI_01625	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HMDFGJHI_01626	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMDFGJHI_01627	1.02e-66	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HMDFGJHI_01628	3.4e-177	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HMDFGJHI_01629	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HMDFGJHI_01630	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HMDFGJHI_01631	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HMDFGJHI_01632	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMDFGJHI_01633	6.4e-122	-	-	-	-	-	-	-	-
HMDFGJHI_01634	1.1e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HMDFGJHI_01635	1.94e-97	-	-	-	-	-	-	-	-
HMDFGJHI_01636	1.09e-86	-	-	-	-	-	-	-	-
HMDFGJHI_01637	2.3e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HMDFGJHI_01638	6.27e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HMDFGJHI_01639	1.56e-281	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HMDFGJHI_01640	1.67e-145	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMDFGJHI_01641	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMDFGJHI_01642	1.38e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HMDFGJHI_01644	1.75e-43	-	-	-	-	-	-	-	-
HMDFGJHI_01645	4.15e-183	-	-	-	Q	-	-	-	Methyltransferase
HMDFGJHI_01646	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HMDFGJHI_01647	1.17e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HMDFGJHI_01648	4.57e-135	-	-	-	K	-	-	-	Helix-turn-helix domain
HMDFGJHI_01649	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMDFGJHI_01650	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HMDFGJHI_01651	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HMDFGJHI_01652	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMDFGJHI_01653	2.05e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMDFGJHI_01654	6.62e-62	-	-	-	-	-	-	-	-
HMDFGJHI_01655	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMDFGJHI_01656	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HMDFGJHI_01657	1.73e-217	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMDFGJHI_01658	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HMDFGJHI_01659	2.52e-79	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HMDFGJHI_01660	5.51e-173	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HMDFGJHI_01661	0.0	cps4J	-	-	S	-	-	-	MatE
HMDFGJHI_01662	2.39e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HMDFGJHI_01663	1.01e-292	-	-	-	-	-	-	-	-
HMDFGJHI_01664	5.46e-235	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HMDFGJHI_01665	1.4e-259	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HMDFGJHI_01666	5.49e-163	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HMDFGJHI_01667	1.62e-228	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HMDFGJHI_01668	3.74e-187	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HMDFGJHI_01669	1.66e-155	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HMDFGJHI_01670	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
HMDFGJHI_01671	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMDFGJHI_01672	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_01673	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HMDFGJHI_01674	5.12e-31	-	-	-	-	-	-	-	-
HMDFGJHI_01675	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HMDFGJHI_01676	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HMDFGJHI_01677	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HMDFGJHI_01678	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMDFGJHI_01679	3.75e-287	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMDFGJHI_01680	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMDFGJHI_01681	5.89e-204	-	-	-	S	-	-	-	Tetratricopeptide repeat
HMDFGJHI_01682	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMDFGJHI_01683	5.25e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMDFGJHI_01684	3.84e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMDFGJHI_01685	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMDFGJHI_01686	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HMDFGJHI_01687	5.09e-241	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HMDFGJHI_01688	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HMDFGJHI_01689	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HMDFGJHI_01690	2.56e-162	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HMDFGJHI_01691	4.27e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HMDFGJHI_01692	2.99e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMDFGJHI_01693	4.98e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HMDFGJHI_01694	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HMDFGJHI_01695	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HMDFGJHI_01696	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HMDFGJHI_01697	0.0	-	-	-	-	-	-	-	-
HMDFGJHI_01698	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HMDFGJHI_01699	9.51e-135	-	-	-	-	-	-	-	-
HMDFGJHI_01700	1.1e-257	-	-	-	-	-	-	-	-
HMDFGJHI_01701	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HMDFGJHI_01702	5e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HMDFGJHI_01703	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HMDFGJHI_01704	1.02e-207	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HMDFGJHI_01705	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HMDFGJHI_01706	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMDFGJHI_01707	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HMDFGJHI_01708	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HMDFGJHI_01709	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMDFGJHI_01710	6.45e-111	-	-	-	-	-	-	-	-
HMDFGJHI_01711	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HMDFGJHI_01712	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMDFGJHI_01713	5.96e-241	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HMDFGJHI_01714	6.21e-39	-	-	-	-	-	-	-	-
HMDFGJHI_01715	9.21e-169	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HMDFGJHI_01716	1.6e-221	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMDFGJHI_01717	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMDFGJHI_01718	1.02e-155	-	-	-	S	-	-	-	repeat protein
HMDFGJHI_01719	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HMDFGJHI_01720	0.0	-	-	-	N	-	-	-	domain, Protein
HMDFGJHI_01721	7.05e-248	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HMDFGJHI_01722	3.57e-154	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HMDFGJHI_01723	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HMDFGJHI_01724	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HMDFGJHI_01725	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMDFGJHI_01726	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HMDFGJHI_01727	1.06e-277	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HMDFGJHI_01728	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMDFGJHI_01729	7.74e-47	-	-	-	-	-	-	-	-
HMDFGJHI_01730	1.43e-124	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HMDFGJHI_01731	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMDFGJHI_01732	2.05e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HMDFGJHI_01733	2.57e-47	-	-	-	K	-	-	-	LytTr DNA-binding domain
HMDFGJHI_01734	1.47e-100	-	-	-	U	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HMDFGJHI_01735	3.64e-101	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HMDFGJHI_01736	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMDFGJHI_01737	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HMDFGJHI_01738	3.41e-186	ylmH	-	-	S	-	-	-	S4 domain protein
HMDFGJHI_01739	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HMDFGJHI_01740	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMDFGJHI_01741	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMDFGJHI_01742	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMDFGJHI_01743	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMDFGJHI_01744	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMDFGJHI_01745	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMDFGJHI_01746	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMDFGJHI_01747	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HMDFGJHI_01748	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HMDFGJHI_01749	8.62e-225	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMDFGJHI_01750	1.35e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HMDFGJHI_01751	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HMDFGJHI_01752	4.99e-224	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HMDFGJHI_01753	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HMDFGJHI_01754	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMDFGJHI_01755	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HMDFGJHI_01756	2.17e-302	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HMDFGJHI_01758	3.74e-206	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HMDFGJHI_01759	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMDFGJHI_01760	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HMDFGJHI_01761	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HMDFGJHI_01762	6.5e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HMDFGJHI_01763	7.21e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HMDFGJHI_01764	1.09e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HMDFGJHI_01765	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMDFGJHI_01766	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HMDFGJHI_01767	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HMDFGJHI_01768	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HMDFGJHI_01769	3.19e-264	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HMDFGJHI_01770	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMDFGJHI_01771	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMDFGJHI_01772	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HMDFGJHI_01773	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HMDFGJHI_01795	1.29e-83	-	-	-	-	-	-	-	-
HMDFGJHI_01796	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HMDFGJHI_01797	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMDFGJHI_01798	7.18e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HMDFGJHI_01799	3.3e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HMDFGJHI_01800	1.19e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMDFGJHI_01801	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HMDFGJHI_01802	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HMDFGJHI_01803	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HMDFGJHI_01804	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HMDFGJHI_01805	3.31e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMDFGJHI_01806	1.56e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HMDFGJHI_01808	1.85e-112	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HMDFGJHI_01809	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HMDFGJHI_01810	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HMDFGJHI_01811	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HMDFGJHI_01812	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HMDFGJHI_01813	1.55e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HMDFGJHI_01814	1.19e-204	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMDFGJHI_01815	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HMDFGJHI_01816	8.49e-66	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HMDFGJHI_01817	1.59e-210	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HMDFGJHI_01818	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HMDFGJHI_01819	1.55e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HMDFGJHI_01820	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMDFGJHI_01821	4.51e-79	-	-	-	-	-	-	-	-
HMDFGJHI_01822	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMDFGJHI_01823	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HMDFGJHI_01824	4.54e-287	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMDFGJHI_01825	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMDFGJHI_01826	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HMDFGJHI_01827	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HMDFGJHI_01828	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMDFGJHI_01829	8.74e-195	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HMDFGJHI_01830	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HMDFGJHI_01831	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HMDFGJHI_01832	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMDFGJHI_01833	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HMDFGJHI_01834	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HMDFGJHI_01835	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMDFGJHI_01836	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HMDFGJHI_01837	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMDFGJHI_01838	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMDFGJHI_01839	3.39e-226	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HMDFGJHI_01840	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMDFGJHI_01841	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HMDFGJHI_01842	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMDFGJHI_01843	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMDFGJHI_01844	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMDFGJHI_01845	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMDFGJHI_01846	2.07e-118	-	-	-	-	-	-	-	-
HMDFGJHI_01847	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HMDFGJHI_01848	1.35e-93	-	-	-	-	-	-	-	-
HMDFGJHI_01849	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMDFGJHI_01850	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMDFGJHI_01851	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HMDFGJHI_01852	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HMDFGJHI_01853	9.9e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMDFGJHI_01854	2.21e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HMDFGJHI_01855	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMDFGJHI_01856	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HMDFGJHI_01857	3.84e-316	ymfH	-	-	S	-	-	-	Peptidase M16
HMDFGJHI_01858	1.44e-295	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HMDFGJHI_01859	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HMDFGJHI_01860	4.34e-198	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HMDFGJHI_01861	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_01862	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HMDFGJHI_01863	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HMDFGJHI_01864	2.2e-149	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HMDFGJHI_01865	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HMDFGJHI_01866	2.17e-183	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HMDFGJHI_01867	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HMDFGJHI_01868	1.35e-149	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HMDFGJHI_01869	5.62e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HMDFGJHI_01870	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMDFGJHI_01871	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMDFGJHI_01872	1.83e-298	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HMDFGJHI_01873	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMDFGJHI_01874	2.22e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HMDFGJHI_01875	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMDFGJHI_01876	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HMDFGJHI_01877	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMDFGJHI_01878	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HMDFGJHI_01879	1.15e-104	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HMDFGJHI_01880	1.57e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HMDFGJHI_01881	5.51e-60	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMDFGJHI_01882	1.19e-289	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HMDFGJHI_01883	3.43e-55	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HMDFGJHI_01884	5.82e-139	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
HMDFGJHI_01885	4.54e-132	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HMDFGJHI_01886	3.79e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMDFGJHI_01887	1.31e-119	-	-	-	K	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
HMDFGJHI_01888	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HMDFGJHI_01889	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HMDFGJHI_01890	1.34e-52	-	-	-	-	-	-	-	-
HMDFGJHI_01891	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HMDFGJHI_01892	3.44e-262	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HMDFGJHI_01893	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMDFGJHI_01894	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HMDFGJHI_01895	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HMDFGJHI_01896	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HMDFGJHI_01897	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HMDFGJHI_01898	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HMDFGJHI_01899	3.03e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HMDFGJHI_01900	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HMDFGJHI_01901	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMDFGJHI_01902	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HMDFGJHI_01903	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HMDFGJHI_01904	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HMDFGJHI_01905	2.16e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HMDFGJHI_01906	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HMDFGJHI_01907	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HMDFGJHI_01908	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMDFGJHI_01909	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HMDFGJHI_01910	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMDFGJHI_01911	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMDFGJHI_01912	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMDFGJHI_01913	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMDFGJHI_01914	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMDFGJHI_01915	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMDFGJHI_01916	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HMDFGJHI_01917	2.49e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HMDFGJHI_01918	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMDFGJHI_01919	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMDFGJHI_01920	4.39e-244	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMDFGJHI_01921	3.44e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMDFGJHI_01922	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMDFGJHI_01923	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HMDFGJHI_01924	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HMDFGJHI_01925	1.06e-174	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HMDFGJHI_01926	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HMDFGJHI_01927	2.65e-245	ampC	-	-	V	-	-	-	Beta-lactamase
HMDFGJHI_01928	2.1e-41	-	-	-	-	-	-	-	-
HMDFGJHI_01929	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HMDFGJHI_01930	1.33e-77	-	-	-	-	-	-	-	-
HMDFGJHI_01931	6.55e-183	-	-	-	-	-	-	-	-
HMDFGJHI_01932	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HMDFGJHI_01933	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_01934	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HMDFGJHI_01935	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HMDFGJHI_01938	2e-58	-	-	-	S	-	-	-	Bacteriophage holin
HMDFGJHI_01939	1.53e-62	-	-	-	-	-	-	-	-
HMDFGJHI_01940	7.37e-231	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HMDFGJHI_01942	5.3e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF1617)
HMDFGJHI_01943	0.0	-	-	-	LM	-	-	-	DNA recombination
HMDFGJHI_01944	2.29e-81	-	-	-	-	-	-	-	-
HMDFGJHI_01945	0.0	-	-	-	D	-	-	-	domain protein
HMDFGJHI_01946	3.76e-32	-	-	-	-	-	-	-	-
HMDFGJHI_01947	1.42e-83	-	-	-	-	-	-	-	-
HMDFGJHI_01948	7.42e-102	-	-	-	S	-	-	-	Phage tail tube protein, TTP
HMDFGJHI_01949	4.96e-72	-	-	-	-	-	-	-	-
HMDFGJHI_01950	7.59e-115	-	-	-	-	-	-	-	-
HMDFGJHI_01951	9.63e-68	-	-	-	-	-	-	-	-
HMDFGJHI_01952	5.01e-69	-	-	-	-	-	-	-	-
HMDFGJHI_01954	2.08e-222	-	-	-	S	-	-	-	Phage major capsid protein E
HMDFGJHI_01955	1.16e-63	-	-	-	-	-	-	-	-
HMDFGJHI_01958	3.05e-41	-	-	-	-	-	-	-	-
HMDFGJHI_01959	0.0	-	-	-	S	-	-	-	Phage Mu protein F like protein
HMDFGJHI_01960	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HMDFGJHI_01961	2.08e-304	-	-	-	S	-	-	-	Terminase-like family
HMDFGJHI_01962	5.06e-84	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HMDFGJHI_01968	3.71e-105	arpU	-	-	S	-	-	-	Transcriptional regulator, ArpU family
HMDFGJHI_01969	4.26e-07	-	-	-	-	-	-	-	-
HMDFGJHI_01970	6.67e-86	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HMDFGJHI_01973	4.88e-200	-	-	-	S	-	-	-	IstB-like ATP binding protein
HMDFGJHI_01974	1.19e-37	-	-	-	L	-	-	-	DnaD domain protein
HMDFGJHI_01975	1.35e-57	-	-	-	S	-	-	-	ERF superfamily
HMDFGJHI_01977	2.21e-89	-	-	-	-	-	-	-	-
HMDFGJHI_01979	1.56e-103	-	-	-	-	-	-	-	-
HMDFGJHI_01980	7.71e-71	-	-	-	-	-	-	-	-
HMDFGJHI_01983	1.13e-36	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HMDFGJHI_01984	8.29e-51	-	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
HMDFGJHI_01986	2.06e-50	-	-	-	K	-	-	-	Helix-turn-helix
HMDFGJHI_01987	1.32e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
HMDFGJHI_01988	6.69e-98	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HMDFGJHI_01989	2.64e-202	-	-	-	J	-	-	-	Domain of unknown function (DUF4041)
HMDFGJHI_01990	4.17e-60	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
HMDFGJHI_01991	8.96e-68	-	-	-	-	-	-	-	-
HMDFGJHI_01992	1.63e-19	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HMDFGJHI_01997	7.78e-46	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMDFGJHI_01999	1.3e-45	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HMDFGJHI_02004	5.36e-59	-	-	-	-	-	-	-	-
HMDFGJHI_02005	1.39e-134	-	-	-	S	-	-	-	Domain of unknown function DUF1829
HMDFGJHI_02006	1.09e-277	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMDFGJHI_02008	1.98e-40	-	-	-	-	-	-	-	-
HMDFGJHI_02011	7.78e-76	-	-	-	-	-	-	-	-
HMDFGJHI_02012	1.62e-53	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HMDFGJHI_02015	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HMDFGJHI_02016	9.78e-257	-	-	-	S	-	-	-	Phage portal protein
HMDFGJHI_02017	2.13e-05	-	-	-	-	-	-	-	-
HMDFGJHI_02018	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HMDFGJHI_02019	7.73e-109	-	-	-	L	-	-	-	overlaps another CDS with the same product name
HMDFGJHI_02020	1.05e-88	-	-	-	L	-	-	-	HNH endonuclease
HMDFGJHI_02021	1.87e-65	-	-	-	S	-	-	-	Head-tail joining protein
HMDFGJHI_02022	1e-31	-	-	-	-	-	-	-	-
HMDFGJHI_02024	9.61e-64	-	-	-	S	-	-	-	Phage plasmid primase P4 family
HMDFGJHI_02025	3.11e-178	-	-	-	L	-	-	-	DNA replication protein
HMDFGJHI_02026	2.62e-40	-	-	-	-	-	-	-	-
HMDFGJHI_02028	2.12e-17	ansR	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_02029	1.03e-288	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMDFGJHI_02030	1.28e-51	-	-	-	-	-	-	-	-
HMDFGJHI_02031	9.28e-58	-	-	-	-	-	-	-	-
HMDFGJHI_02032	1.27e-109	-	-	-	K	-	-	-	MarR family
HMDFGJHI_02033	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HMDFGJHI_02034	0.0	inlJ	-	-	M	-	-	-	MucBP domain
HMDFGJHI_02035	6.58e-24	-	-	-	-	-	-	-	-
HMDFGJHI_02036	3.26e-24	-	-	-	-	-	-	-	-
HMDFGJHI_02037	1.56e-22	-	-	-	-	-	-	-	-
HMDFGJHI_02038	1.07e-26	-	-	-	-	-	-	-	-
HMDFGJHI_02039	9.35e-24	-	-	-	-	-	-	-	-
HMDFGJHI_02040	9.35e-24	-	-	-	-	-	-	-	-
HMDFGJHI_02041	9.35e-24	-	-	-	-	-	-	-	-
HMDFGJHI_02042	2.16e-26	-	-	-	-	-	-	-	-
HMDFGJHI_02043	4.63e-24	-	-	-	-	-	-	-	-
HMDFGJHI_02044	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HMDFGJHI_02045	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMDFGJHI_02046	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_02047	2.1e-33	-	-	-	-	-	-	-	-
HMDFGJHI_02048	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HMDFGJHI_02049	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HMDFGJHI_02050	7.43e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HMDFGJHI_02051	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HMDFGJHI_02052	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HMDFGJHI_02053	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HMDFGJHI_02054	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HMDFGJHI_02055	1.26e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HMDFGJHI_02057	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HMDFGJHI_02058	1.31e-64	-	-	-	-	-	-	-	-
HMDFGJHI_02059	1.96e-273	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HMDFGJHI_02060	1.9e-176	-	-	-	F	-	-	-	NUDIX domain
HMDFGJHI_02061	2.68e-32	-	-	-	-	-	-	-	-
HMDFGJHI_02063	1.65e-206	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMDFGJHI_02064	1.37e-219	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HMDFGJHI_02065	5.92e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HMDFGJHI_02066	2.29e-48	-	-	-	-	-	-	-	-
HMDFGJHI_02067	1.11e-45	-	-	-	-	-	-	-	-
HMDFGJHI_02068	1.62e-277	-	-	-	T	-	-	-	diguanylate cyclase
HMDFGJHI_02069	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HMDFGJHI_02070	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HMDFGJHI_02071	4.74e-106	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMDFGJHI_02072	9.2e-62	-	-	-	-	-	-	-	-
HMDFGJHI_02073	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HMDFGJHI_02074	5.32e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMDFGJHI_02075	5.97e-210	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HMDFGJHI_02076	1.01e-293	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HMDFGJHI_02077	3.52e-311	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HMDFGJHI_02078	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HMDFGJHI_02079	2.79e-226	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HMDFGJHI_02080	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HMDFGJHI_02081	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_02082	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HMDFGJHI_02083	9.51e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HMDFGJHI_02084	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HMDFGJHI_02085	6.8e-123	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HMDFGJHI_02086	3.38e-252	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMDFGJHI_02087	5.11e-67	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HMDFGJHI_02088	2.49e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMDFGJHI_02089	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMDFGJHI_02090	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMDFGJHI_02091	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMDFGJHI_02092	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HMDFGJHI_02093	4.51e-298	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMDFGJHI_02094	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HMDFGJHI_02095	1.09e-273	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HMDFGJHI_02096	6.46e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HMDFGJHI_02097	1.07e-282	ysaA	-	-	V	-	-	-	RDD family
HMDFGJHI_02098	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HMDFGJHI_02099	1.71e-67	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HMDFGJHI_02100	2.54e-17	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HMDFGJHI_02101	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMDFGJHI_02102	4.7e-237	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMDFGJHI_02103	1.45e-46	-	-	-	-	-	-	-	-
HMDFGJHI_02104	3.1e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HMDFGJHI_02105	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HMDFGJHI_02106	0.0	-	-	-	M	-	-	-	domain protein
HMDFGJHI_02107	3e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HMDFGJHI_02108	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMDFGJHI_02109	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HMDFGJHI_02110	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HMDFGJHI_02111	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMDFGJHI_02112	1.85e-248	-	-	-	S	-	-	-	domain, Protein
HMDFGJHI_02113	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HMDFGJHI_02114	2.57e-128	-	-	-	C	-	-	-	Nitroreductase family
HMDFGJHI_02115	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HMDFGJHI_02116	2.43e-209	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMDFGJHI_02117	8.1e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HMDFGJHI_02118	3.16e-232	-	-	-	GK	-	-	-	ROK family
HMDFGJHI_02119	2.08e-199	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMDFGJHI_02120	1.38e-171	rdrA	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HMDFGJHI_02121	0.0	pflD	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HMDFGJHI_02122	5.85e-226	-	-	-	K	-	-	-	sugar-binding domain protein
HMDFGJHI_02123	1.81e-160	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
HMDFGJHI_02124	4.13e-180	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMDFGJHI_02125	2.89e-224	ccpB	-	-	K	-	-	-	lacI family
HMDFGJHI_02126	1.77e-201	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HMDFGJHI_02127	6.09e-228	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HMDFGJHI_02128	1.89e-254	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HMDFGJHI_02129	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HMDFGJHI_02130	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMDFGJHI_02131	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HMDFGJHI_02132	1.79e-170	-	-	-	-	-	-	-	-
HMDFGJHI_02133	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HMDFGJHI_02134	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HMDFGJHI_02135	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HMDFGJHI_02136	2.29e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HMDFGJHI_02137	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HMDFGJHI_02138	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_02139	1.86e-210	-	-	-	-	-	-	-	-
HMDFGJHI_02140	7.15e-75	-	-	-	-	-	-	-	-
HMDFGJHI_02141	1.44e-65	-	-	-	-	-	-	-	-
HMDFGJHI_02142	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMDFGJHI_02143	1e-89	-	-	-	-	-	-	-	-
HMDFGJHI_02144	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HMDFGJHI_02145	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HMDFGJHI_02146	2.72e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HMDFGJHI_02147	3.89e-62	-	-	-	-	-	-	-	-
HMDFGJHI_02148	1.57e-71	-	-	-	-	-	-	-	-
HMDFGJHI_02149	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HMDFGJHI_02150	4.05e-98	-	-	-	-	-	-	-	-
HMDFGJHI_02151	4.15e-78	-	-	-	-	-	-	-	-
HMDFGJHI_02152	3.5e-249	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HMDFGJHI_02153	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HMDFGJHI_02154	1.63e-95	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HMDFGJHI_02155	3.82e-188	agaD	-	-	G	ko:K02747,ko:K02796,ko:K10986	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HMDFGJHI_02156	1.74e-183	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HMDFGJHI_02157	4.28e-112	-	2.7.1.191	-	K	ko:K02745,ko:K02794,ko:K10984	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMDFGJHI_02158	5.87e-166	-	-	-	K	ko:K03710	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HMDFGJHI_02159	2.51e-103	uspA3	-	-	T	-	-	-	universal stress protein
HMDFGJHI_02160	1.84e-205	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HMDFGJHI_02161	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HMDFGJHI_02162	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HMDFGJHI_02163	6.19e-284	-	-	-	M	-	-	-	Glycosyl transferases group 1
HMDFGJHI_02164	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HMDFGJHI_02165	1.52e-204	-	-	-	S	-	-	-	Putative esterase
HMDFGJHI_02166	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_02167	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMDFGJHI_02168	6.08e-179	-	-	-	-	-	-	-	-
HMDFGJHI_02169	4.85e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HMDFGJHI_02170	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HMDFGJHI_02171	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HMDFGJHI_02172	2.2e-79	-	-	-	-	-	-	-	-
HMDFGJHI_02173	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HMDFGJHI_02174	2.97e-76	-	-	-	-	-	-	-	-
HMDFGJHI_02175	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HMDFGJHI_02176	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HMDFGJHI_02177	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HMDFGJHI_02178	1.17e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
HMDFGJHI_02179	2.84e-82	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMDFGJHI_02180	2.19e-220	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HMDFGJHI_02181	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HMDFGJHI_02182	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMDFGJHI_02183	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HMDFGJHI_02184	1.02e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HMDFGJHI_02185	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMDFGJHI_02186	3.59e-26	-	-	-	-	-	-	-	-
HMDFGJHI_02187	6.68e-139	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HMDFGJHI_02188	8.13e-208	mleR	-	-	K	-	-	-	LysR family
HMDFGJHI_02189	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HMDFGJHI_02190	1.57e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HMDFGJHI_02191	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HMDFGJHI_02192	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HMDFGJHI_02193	3.84e-218	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HMDFGJHI_02194	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMDFGJHI_02195	1.09e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMDFGJHI_02196	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMDFGJHI_02197	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HMDFGJHI_02198	3.36e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HMDFGJHI_02199	1.95e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMDFGJHI_02200	1.22e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HMDFGJHI_02201	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMDFGJHI_02202	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HMDFGJHI_02203	4.41e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HMDFGJHI_02204	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HMDFGJHI_02205	4.71e-208	-	-	-	GM	-	-	-	NmrA-like family
HMDFGJHI_02206	1.77e-199	-	-	-	T	-	-	-	EAL domain
HMDFGJHI_02207	2.62e-121	-	-	-	-	-	-	-	-
HMDFGJHI_02208	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HMDFGJHI_02209	7.46e-157	-	-	-	E	-	-	-	Methionine synthase
HMDFGJHI_02210	2.71e-280	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HMDFGJHI_02211	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HMDFGJHI_02212	1.79e-131	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMDFGJHI_02213	9.93e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HMDFGJHI_02214	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMDFGJHI_02215	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMDFGJHI_02216	2.82e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMDFGJHI_02217	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMDFGJHI_02218	3.95e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HMDFGJHI_02219	6.77e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMDFGJHI_02220	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMDFGJHI_02221	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HMDFGJHI_02222	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HMDFGJHI_02223	1.16e-242	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HMDFGJHI_02224	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HMDFGJHI_02225	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HMDFGJHI_02226	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMDFGJHI_02227	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HMDFGJHI_02228	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_02229	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HMDFGJHI_02230	4.76e-56	-	-	-	-	-	-	-	-
HMDFGJHI_02231	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HMDFGJHI_02232	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_02233	3.41e-190	-	-	-	-	-	-	-	-
HMDFGJHI_02234	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
HMDFGJHI_02235	8.93e-47	-	-	-	-	-	-	-	-
HMDFGJHI_02236	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HMDFGJHI_02237	1.02e-113	-	-	-	-	-	-	-	-
HMDFGJHI_02238	1.4e-65	-	-	-	-	-	-	-	-
HMDFGJHI_02239	4.79e-13	-	-	-	-	-	-	-	-
HMDFGJHI_02240	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HMDFGJHI_02241	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HMDFGJHI_02242	1.52e-151	-	-	-	-	-	-	-	-
HMDFGJHI_02243	1.21e-69	-	-	-	-	-	-	-	-
HMDFGJHI_02245	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HMDFGJHI_02246	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HMDFGJHI_02247	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HMDFGJHI_02248	2.96e-41	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HMDFGJHI_02249	1.76e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HMDFGJHI_02250	2.28e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HMDFGJHI_02251	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HMDFGJHI_02252	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HMDFGJHI_02253	5.6e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HMDFGJHI_02254	3.48e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HMDFGJHI_02255	1.8e-293	-	-	-	S	-	-	-	Sterol carrier protein domain
HMDFGJHI_02256	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HMDFGJHI_02257	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMDFGJHI_02258	2.13e-152	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_02259	9.76e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HMDFGJHI_02260	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HMDFGJHI_02261	9.53e-317	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HMDFGJHI_02262	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMDFGJHI_02263	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMDFGJHI_02264	2.73e-73	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HMDFGJHI_02265	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMDFGJHI_02266	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HMDFGJHI_02267	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HMDFGJHI_02268	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HMDFGJHI_02269	7.63e-107	-	-	-	-	-	-	-	-
HMDFGJHI_02270	5.06e-196	-	-	-	S	-	-	-	hydrolase
HMDFGJHI_02271	1.51e-235	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMDFGJHI_02272	2.8e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HMDFGJHI_02273	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HMDFGJHI_02274	3.1e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HMDFGJHI_02275	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HMDFGJHI_02276	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HMDFGJHI_02277	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HMDFGJHI_02278	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HMDFGJHI_02279	4.3e-44	-	-	-	-	-	-	-	-
HMDFGJHI_02280	2.55e-166	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HMDFGJHI_02281	0.0	ycaM	-	-	E	-	-	-	amino acid
HMDFGJHI_02282	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HMDFGJHI_02283	1.42e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HMDFGJHI_02284	2.95e-207	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HMDFGJHI_02285	1.07e-208	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_02287	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HMDFGJHI_02288	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMDFGJHI_02289	1.27e-143	-	-	-	-	-	-	-	-
HMDFGJHI_02290	7.58e-244	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HMDFGJHI_02291	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
HMDFGJHI_02292	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HMDFGJHI_02293	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HMDFGJHI_02294	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HMDFGJHI_02295	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMDFGJHI_02296	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HMDFGJHI_02297	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HMDFGJHI_02298	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_02299	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HMDFGJHI_02300	2e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HMDFGJHI_02301	3.55e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HMDFGJHI_02302	1.97e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMDFGJHI_02303	9.01e-155	-	-	-	S	-	-	-	Membrane
HMDFGJHI_02304	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HMDFGJHI_02305	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HMDFGJHI_02306	3.04e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMDFGJHI_02307	7.22e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HMDFGJHI_02308	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HMDFGJHI_02309	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HMDFGJHI_02310	8.99e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HMDFGJHI_02311	4.38e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HMDFGJHI_02312	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HMDFGJHI_02313	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HMDFGJHI_02314	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HMDFGJHI_02316	4.96e-88	-	-	-	M	-	-	-	LysM domain
HMDFGJHI_02317	1.6e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HMDFGJHI_02318	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_02319	7.88e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HMDFGJHI_02320	3.63e-165	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMDFGJHI_02321	1.16e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HMDFGJHI_02322	2.27e-98	yphH	-	-	S	-	-	-	Cupin domain
HMDFGJHI_02323	7.37e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HMDFGJHI_02324	1.46e-299	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HMDFGJHI_02325	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HMDFGJHI_02326	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_02328	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMDFGJHI_02329	1.24e-138	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HMDFGJHI_02330	5.98e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HMDFGJHI_02331	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMDFGJHI_02332	3.19e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HMDFGJHI_02333	8.4e-112	-	-	-	-	-	-	-	-
HMDFGJHI_02334	6.25e-112	yvbK	-	-	K	-	-	-	GNAT family
HMDFGJHI_02335	2.8e-49	-	-	-	-	-	-	-	-
HMDFGJHI_02336	2.81e-64	-	-	-	-	-	-	-	-
HMDFGJHI_02337	1.1e-144	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HMDFGJHI_02338	2.65e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HMDFGJHI_02339	1.83e-201	-	-	-	K	-	-	-	LysR substrate binding domain
HMDFGJHI_02340	1.64e-130	-	-	-	GM	-	-	-	NAD(P)H-binding
HMDFGJHI_02341	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HMDFGJHI_02342	3.38e-193	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HMDFGJHI_02343	2.21e-46	-	-	-	-	-	-	-	-
HMDFGJHI_02344	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HMDFGJHI_02345	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HMDFGJHI_02346	7.47e-164	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HMDFGJHI_02347	1.21e-81	-	-	-	-	-	-	-	-
HMDFGJHI_02348	5.52e-133	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HMDFGJHI_02349	2.17e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HMDFGJHI_02350	1.86e-132	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HMDFGJHI_02351	1.8e-249	-	-	-	C	-	-	-	Aldo/keto reductase family
HMDFGJHI_02353	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMDFGJHI_02354	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMDFGJHI_02355	4.51e-314	-	-	-	EGP	-	-	-	Major Facilitator
HMDFGJHI_02358	1.58e-230	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HMDFGJHI_02359	8.85e-141	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HMDFGJHI_02360	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HMDFGJHI_02361	4.36e-197	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HMDFGJHI_02362	2.81e-134	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HMDFGJHI_02363	7.2e-125	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HMDFGJHI_02364	1.48e-167	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HMDFGJHI_02365	9.53e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HMDFGJHI_02366	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HMDFGJHI_02367	4.68e-190	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HMDFGJHI_02368	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HMDFGJHI_02369	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HMDFGJHI_02370	2.84e-266	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HMDFGJHI_02371	2.67e-220	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMDFGJHI_02372	1.76e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HMDFGJHI_02373	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HMDFGJHI_02374	1.58e-203	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMDFGJHI_02375	5.86e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HMDFGJHI_02376	9.98e-47	-	-	-	-	-	-	-	-
HMDFGJHI_02377	1.15e-294	-	-	-	-	-	-	-	-
HMDFGJHI_02378	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HMDFGJHI_02379	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMDFGJHI_02380	2.05e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HMDFGJHI_02381	3.29e-162	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HMDFGJHI_02382	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMDFGJHI_02383	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HMDFGJHI_02384	3.68e-107	-	-	-	-	-	-	-	-
HMDFGJHI_02385	8.48e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMDFGJHI_02386	6.48e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMDFGJHI_02387	1.26e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMDFGJHI_02388	3.7e-30	-	-	-	-	-	-	-	-
HMDFGJHI_02389	6.36e-130	-	-	-	-	-	-	-	-
HMDFGJHI_02390	5.12e-212	-	-	-	K	-	-	-	LysR substrate binding domain
HMDFGJHI_02391	1.24e-313	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HMDFGJHI_02392	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HMDFGJHI_02393	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HMDFGJHI_02394	1.37e-182	-	-	-	S	-	-	-	zinc-ribbon domain
HMDFGJHI_02396	4.29e-50	-	-	-	-	-	-	-	-
HMDFGJHI_02397	1.42e-169	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HMDFGJHI_02398	4.07e-232	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HMDFGJHI_02399	0.0	-	-	-	I	-	-	-	acetylesterase activity
HMDFGJHI_02400	2.25e-297	-	-	-	M	-	-	-	Collagen binding domain
HMDFGJHI_02401	1.4e-205	yicL	-	-	EG	-	-	-	EamA-like transporter family
HMDFGJHI_02402	1.02e-164	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HMDFGJHI_02403	3.53e-227	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HMDFGJHI_02404	2.51e-145	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HMDFGJHI_02405	8.76e-63	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HMDFGJHI_02406	7.52e-207	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HMDFGJHI_02407	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HMDFGJHI_02408	5.24e-124	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HMDFGJHI_02409	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
HMDFGJHI_02410	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HMDFGJHI_02411	7.52e-139	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMDFGJHI_02412	6.48e-195	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HMDFGJHI_02413	7.28e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HMDFGJHI_02414	0.0	-	-	-	-	-	-	-	-
HMDFGJHI_02415	1.4e-82	-	-	-	-	-	-	-	-
HMDFGJHI_02416	7.52e-240	-	-	-	S	-	-	-	Cell surface protein
HMDFGJHI_02417	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMDFGJHI_02418	3.67e-72	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HMDFGJHI_02419	1.67e-49	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HMDFGJHI_02420	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMDFGJHI_02421	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HMDFGJHI_02422	1.88e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HMDFGJHI_02423	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HMDFGJHI_02424	1.48e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HMDFGJHI_02426	1.15e-43	-	-	-	-	-	-	-	-
HMDFGJHI_02427	2.93e-169	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HMDFGJHI_02428	8.26e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HMDFGJHI_02429	4.75e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMDFGJHI_02430	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HMDFGJHI_02431	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HMDFGJHI_02432	7.03e-62	-	-	-	-	-	-	-	-
HMDFGJHI_02433	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HMDFGJHI_02434	1e-63	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HMDFGJHI_02435	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HMDFGJHI_02436	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_02437	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HMDFGJHI_02438	2.03e-84	-	-	-	-	-	-	-	-
HMDFGJHI_02439	7.85e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HMDFGJHI_02440	1.21e-73	-	-	-	-	-	-	-	-
HMDFGJHI_02441	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
HMDFGJHI_02442	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMDFGJHI_02443	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMDFGJHI_02444	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDFGJHI_02445	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMDFGJHI_02446	9.1e-237	-	-	-	GM	-	-	-	Male sterility protein
HMDFGJHI_02447	1.79e-100	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMDFGJHI_02448	4.61e-101	-	-	-	M	-	-	-	LysM domain
HMDFGJHI_02449	4.93e-38	-	-	-	M	-	-	-	Lysin motif
HMDFGJHI_02450	8.82e-44	-	-	-	M	-	-	-	Lysin motif
HMDFGJHI_02451	1.99e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
HMDFGJHI_02452	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HMDFGJHI_02453	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HMDFGJHI_02454	8.76e-121	-	-	-	-	-	-	-	-
HMDFGJHI_02455	2.72e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HMDFGJHI_02456	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
HMDFGJHI_02457	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMDFGJHI_02458	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HMDFGJHI_02459	5.78e-215	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HMDFGJHI_02460	3.05e-95	-	-	-	-	-	-	-	-
HMDFGJHI_02461	2.66e-167	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMDFGJHI_02462	1.88e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HMDFGJHI_02463	1.01e-98	-	-	-	GM	-	-	-	NAD(P)H-binding
HMDFGJHI_02464	1.17e-120	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HMDFGJHI_02465	6.7e-102	yphH	-	-	S	-	-	-	Cupin domain
HMDFGJHI_02466	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
HMDFGJHI_02467	3.83e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
HMDFGJHI_02468	3.41e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HMDFGJHI_02469	2.31e-277	-	-	-	-	-	-	-	-
HMDFGJHI_02470	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMDFGJHI_02471	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_02472	2.15e-225	-	-	-	O	-	-	-	protein import
HMDFGJHI_02473	2.77e-291	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HMDFGJHI_02474	2.43e-208	yhxD	-	-	IQ	-	-	-	KR domain
HMDFGJHI_02476	9.38e-91	-	-	-	-	-	-	-	-
HMDFGJHI_02477	3.51e-185	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMDFGJHI_02478	0.0	-	-	-	E	-	-	-	Amino Acid
HMDFGJHI_02479	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
HMDFGJHI_02480	2.43e-285	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HMDFGJHI_02481	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HMDFGJHI_02482	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HMDFGJHI_02483	1.23e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
HMDFGJHI_02484	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HMDFGJHI_02485	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HMDFGJHI_02486	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HMDFGJHI_02487	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HMDFGJHI_02488	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HMDFGJHI_02489	0.0	-	-	-	-	-	-	-	-
HMDFGJHI_02490	2.69e-99	-	-	-	-	-	-	-	-
HMDFGJHI_02491	1.06e-238	-	-	-	S	-	-	-	Cell surface protein
HMDFGJHI_02492	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMDFGJHI_02493	3.12e-224	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HMDFGJHI_02494	5.83e-87	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HMDFGJHI_02495	2.63e-146	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HMDFGJHI_02496	4.55e-243	ynjC	-	-	S	-	-	-	Cell surface protein
HMDFGJHI_02497	4.48e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMDFGJHI_02498	1.47e-83	-	-	-	-	-	-	-	-
HMDFGJHI_02499	5.84e-295	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HMDFGJHI_02500	4.8e-156	-	-	-	-	-	-	-	-
HMDFGJHI_02501	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HMDFGJHI_02502	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HMDFGJHI_02503	1.81e-272	-	-	-	EGP	-	-	-	Major Facilitator
HMDFGJHI_02504	4.52e-147	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HMDFGJHI_02505	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HMDFGJHI_02506	1.38e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HMDFGJHI_02507	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HMDFGJHI_02508	1.59e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_02509	2.65e-216	-	-	-	GM	-	-	-	NmrA-like family
HMDFGJHI_02510	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HMDFGJHI_02511	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HMDFGJHI_02512	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HMDFGJHI_02513	1.27e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HMDFGJHI_02514	3.27e-170	-	-	-	S	-	-	-	KR domain
HMDFGJHI_02515	2.46e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_02516	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HMDFGJHI_02517	1.09e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HMDFGJHI_02518	1.14e-228	ydhF	-	-	S	-	-	-	Aldo keto reductase
HMDFGJHI_02521	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
HMDFGJHI_02522	2.64e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_02523	1.42e-218	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HMDFGJHI_02524	6.37e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HMDFGJHI_02525	1.49e-227	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMDFGJHI_02526	3.32e-219	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMDFGJHI_02527	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_02528	3.89e-210	-	-	-	GM	-	-	-	NmrA-like family
HMDFGJHI_02529	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMDFGJHI_02530	4.01e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HMDFGJHI_02531	1.83e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HMDFGJHI_02532	3.86e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMDFGJHI_02533	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HMDFGJHI_02534	4.28e-233	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HMDFGJHI_02535	1.1e-115	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMDFGJHI_02536	2.83e-267	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HMDFGJHI_02537	1.97e-151	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_02538	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMDFGJHI_02539	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HMDFGJHI_02540	4.54e-202	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HMDFGJHI_02542	0.0	-	-	-	S	-	-	-	MucBP domain
HMDFGJHI_02544	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HMDFGJHI_02545	1.9e-148	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HMDFGJHI_02546	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMDFGJHI_02547	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDFGJHI_02548	2.09e-85	-	-	-	-	-	-	-	-
HMDFGJHI_02549	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HMDFGJHI_02550	5.15e-16	-	-	-	-	-	-	-	-
HMDFGJHI_02551	6.53e-53	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HMDFGJHI_02552	3.41e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMDFGJHI_02553	5.98e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HMDFGJHI_02554	1.91e-280	-	-	-	S	-	-	-	Membrane
HMDFGJHI_02555	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HMDFGJHI_02556	1.26e-137	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HMDFGJHI_02557	5.52e-55	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HMDFGJHI_02558	2.7e-76	-	-	-	-	-	-	-	-
HMDFGJHI_02559	2.06e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HMDFGJHI_02560	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HMDFGJHI_02561	9.09e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HMDFGJHI_02562	5.19e-50	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HMDFGJHI_02563	3e-47	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMDFGJHI_02564	1.23e-149	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HMDFGJHI_02565	4.01e-142	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HMDFGJHI_02566	1.93e-139	-	-	-	GM	-	-	-	NAD(P)H-binding
HMDFGJHI_02567	5.35e-102	-	-	-	GM	-	-	-	SnoaL-like domain
HMDFGJHI_02568	0.0	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
HMDFGJHI_02569	2.52e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HMDFGJHI_02570	6.49e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_02571	1.34e-05	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HMDFGJHI_02572	8.53e-45	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HMDFGJHI_02574	6.79e-53	-	-	-	-	-	-	-	-
HMDFGJHI_02575	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMDFGJHI_02576	9.26e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HMDFGJHI_02577	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
HMDFGJHI_02578	5.21e-151	-	-	-	-	-	-	-	-
HMDFGJHI_02579	1.05e-294	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HMDFGJHI_02580	9.51e-210	-	-	-	-	-	-	-	-
HMDFGJHI_02581	4.77e-259	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HMDFGJHI_02582	5.03e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HMDFGJHI_02583	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HMDFGJHI_02584	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMDFGJHI_02585	1.49e-72	-	-	-	-	-	-	-	-
HMDFGJHI_02586	9.65e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HMDFGJHI_02587	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HMDFGJHI_02588	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HMDFGJHI_02589	1.66e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HMDFGJHI_02590	2.18e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HMDFGJHI_02591	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HMDFGJHI_02592	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HMDFGJHI_02593	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HMDFGJHI_02594	3.84e-207	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMDFGJHI_02595	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMDFGJHI_02596	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HMDFGJHI_02597	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMDFGJHI_02598	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HMDFGJHI_02599	6.14e-202	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HMDFGJHI_02600	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HMDFGJHI_02601	7.39e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HMDFGJHI_02602	1.81e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HMDFGJHI_02603	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HMDFGJHI_02604	3.45e-198	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HMDFGJHI_02605	2.12e-188	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMDFGJHI_02606	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HMDFGJHI_02607	2.07e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
HMDFGJHI_02608	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HMDFGJHI_02609	4.97e-157	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMDFGJHI_02610	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_02611	2.95e-160	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HMDFGJHI_02612	1.07e-127	-	-	-	KT	-	-	-	response to antibiotic
HMDFGJHI_02613	8.52e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HMDFGJHI_02614	2.1e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HMDFGJHI_02615	4.17e-167	-	-	-	S	-	-	-	Putative adhesin
HMDFGJHI_02616	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMDFGJHI_02617	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMDFGJHI_02618	1.57e-234	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HMDFGJHI_02619	7.52e-263	-	-	-	S	-	-	-	DUF218 domain
HMDFGJHI_02620	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HMDFGJHI_02621	3.56e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HMDFGJHI_02622	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMDFGJHI_02623	6.26e-101	-	-	-	-	-	-	-	-
HMDFGJHI_02624	4.17e-263	-	4.1.1.45	-	E	ko:K03392,ko:K07045	ko00380,ko01100,map00380,map01100	ko00000,ko00001,ko00002,ko01000	amidohydrolase
HMDFGJHI_02625	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMDFGJHI_02626	3.33e-306	-	-	-	S	-	-	-	Neutral/alkaline non-lysosomal ceramidase, N-terminal
HMDFGJHI_02627	6.36e-297	-	-	-	-	-	-	-	-
HMDFGJHI_02628	3.91e-211	-	-	-	K	-	-	-	LysR substrate binding domain
HMDFGJHI_02629	5.67e-196	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HMDFGJHI_02630	8.69e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HMDFGJHI_02631	1.29e-115	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HMDFGJHI_02632	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HMDFGJHI_02633	6.69e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HMDFGJHI_02634	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMDFGJHI_02635	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HMDFGJHI_02636	8.23e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMDFGJHI_02637	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HMDFGJHI_02638	8.79e-199	-	-	-	GM	-	-	-	NmrA-like family
HMDFGJHI_02639	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMDFGJHI_02640	1.46e-163	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HMDFGJHI_02642	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HMDFGJHI_02643	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
HMDFGJHI_02644	3.32e-135	-	-	-	-	-	-	-	-
HMDFGJHI_02645	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HMDFGJHI_02646	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
HMDFGJHI_02647	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HMDFGJHI_02648	7.93e-217	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HMDFGJHI_02649	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HMDFGJHI_02650	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HMDFGJHI_02651	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HMDFGJHI_02652	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HMDFGJHI_02653	1.03e-34	-	-	-	-	-	-	-	-
HMDFGJHI_02654	1.21e-151	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HMDFGJHI_02655	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HMDFGJHI_02656	1.04e-212	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HMDFGJHI_02657	4.68e-235	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HMDFGJHI_02658	1.22e-252	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HMDFGJHI_02659	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HMDFGJHI_02660	2.49e-73	-	-	-	S	-	-	-	Enterocin A Immunity
HMDFGJHI_02661	7.41e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMDFGJHI_02662	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMDFGJHI_02663	7.21e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMDFGJHI_02664	1.45e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HMDFGJHI_02665	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMDFGJHI_02667	1.88e-106	-	-	-	-	-	-	-	-
HMDFGJHI_02668	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HMDFGJHI_02670	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HMDFGJHI_02671	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMDFGJHI_02672	3.62e-227	ydbI	-	-	K	-	-	-	AI-2E family transporter
HMDFGJHI_02673	1.01e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HMDFGJHI_02674	3.3e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HMDFGJHI_02675	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HMDFGJHI_02676	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HMDFGJHI_02677	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HMDFGJHI_02678	7.52e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HMDFGJHI_02679	8.03e-28	-	-	-	-	-	-	-	-
HMDFGJHI_02680	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HMDFGJHI_02681	3.94e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HMDFGJHI_02682	6.2e-131	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HMDFGJHI_02683	9.16e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HMDFGJHI_02684	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HMDFGJHI_02685	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HMDFGJHI_02686	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMDFGJHI_02687	1.73e-108	cvpA	-	-	S	-	-	-	Colicin V production protein
HMDFGJHI_02688	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HMDFGJHI_02689	4.41e-316	-	-	-	EGP	-	-	-	Major Facilitator
HMDFGJHI_02691	4.54e-54	-	-	-	-	-	-	-	-
HMDFGJHI_02692	8.82e-124	-	-	-	V	-	-	-	VanZ like family
HMDFGJHI_02693	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
HMDFGJHI_02694	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HMDFGJHI_02695	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMDFGJHI_02696	7.35e-70	-	-	-	S	-	-	-	Pfam:DUF59
HMDFGJHI_02697	1.05e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
HMDFGJHI_02698	2.42e-127	-	-	-	FG	-	-	-	HIT domain
HMDFGJHI_02699	4.9e-49	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HMDFGJHI_02700	4.29e-101	-	-	-	-	-	-	-	-
HMDFGJHI_02701	3.73e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HMDFGJHI_02702	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HMDFGJHI_02703	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HMDFGJHI_02705	9.54e-45	-	-	-	S	-	-	-	YjbR
HMDFGJHI_02706	9.53e-285	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HMDFGJHI_02707	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HMDFGJHI_02708	7.12e-256	glmS2	-	-	M	-	-	-	SIS domain
HMDFGJHI_02709	1.08e-30	-	-	-	S	-	-	-	Belongs to the LOG family
HMDFGJHI_02710	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HMDFGJHI_02711	9.04e-317	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HMDFGJHI_02712	5e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HMDFGJHI_02713	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HMDFGJHI_02714	1.07e-206	-	-	-	GM	-	-	-	NmrA-like family
HMDFGJHI_02715	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HMDFGJHI_02716	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HMDFGJHI_02717	1.41e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HMDFGJHI_02718	1.7e-70	-	-	-	-	-	-	-	-
HMDFGJHI_02719	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HMDFGJHI_02720	2.11e-82	-	-	-	-	-	-	-	-
HMDFGJHI_02721	1.36e-112	-	-	-	-	-	-	-	-
HMDFGJHI_02722	3.22e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HMDFGJHI_02723	2.27e-74	-	-	-	-	-	-	-	-
HMDFGJHI_02724	4.79e-21	-	-	-	-	-	-	-	-
HMDFGJHI_02725	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HMDFGJHI_02726	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HMDFGJHI_02727	3.29e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HMDFGJHI_02728	2.66e-155	-	-	-	S	-	-	-	membrane
HMDFGJHI_02729	1.47e-144	-	-	-	S	-	-	-	VIT family
HMDFGJHI_02730	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HMDFGJHI_02731	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HMDFGJHI_02732	4.83e-98	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HMDFGJHI_02733	4.26e-54	-	-	-	-	-	-	-	-
HMDFGJHI_02734	2.07e-97	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HMDFGJHI_02735	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HMDFGJHI_02736	7.21e-35	-	-	-	-	-	-	-	-
HMDFGJHI_02737	4.39e-66	-	-	-	-	-	-	-	-
HMDFGJHI_02738	8.75e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HMDFGJHI_02739	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HMDFGJHI_02740	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HMDFGJHI_02741	5.99e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HMDFGJHI_02742	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HMDFGJHI_02743	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HMDFGJHI_02744	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HMDFGJHI_02745	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HMDFGJHI_02746	2.8e-205	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HMDFGJHI_02747	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HMDFGJHI_02748	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HMDFGJHI_02749	2.93e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HMDFGJHI_02750	1.05e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HMDFGJHI_02751	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMDFGJHI_02752	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
HMDFGJHI_02753	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HMDFGJHI_02754	1.58e-66	-	-	-	-	-	-	-	-
HMDFGJHI_02755	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HMDFGJHI_02756	0.0	-	-	-	-	-	-	-	-
HMDFGJHI_02757	1.36e-245	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HMDFGJHI_02758	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMDFGJHI_02759	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HMDFGJHI_02760	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HMDFGJHI_02761	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMDFGJHI_02762	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HMDFGJHI_02763	4.45e-38	-	-	-	-	-	-	-	-
HMDFGJHI_02764	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HMDFGJHI_02765	2.04e-107	-	-	-	M	-	-	-	PFAM NLP P60 protein
HMDFGJHI_02766	6.18e-71	-	-	-	-	-	-	-	-
HMDFGJHI_02767	9.96e-82	-	-	-	-	-	-	-	-
HMDFGJHI_02769	8.86e-139	-	-	-	-	-	-	-	-
HMDFGJHI_02770	1.22e-68	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HMDFGJHI_02771	1.13e-204	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HMDFGJHI_02772	6.25e-132	-	-	-	K	-	-	-	transcriptional regulator
HMDFGJHI_02773	1.24e-232	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HMDFGJHI_02774	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HMDFGJHI_02775	3.55e-164	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HMDFGJHI_02776	2.93e-234	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HMDFGJHI_02777	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HMDFGJHI_02778	8.08e-184	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMDFGJHI_02779	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HMDFGJHI_02780	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HMDFGJHI_02781	1.34e-26	-	-	-	-	-	-	-	-
HMDFGJHI_02782	1.43e-124	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HMDFGJHI_02783	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HMDFGJHI_02784	2.59e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HMDFGJHI_02785	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HMDFGJHI_02786	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMDFGJHI_02787	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HMDFGJHI_02788	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HMDFGJHI_02789	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HMDFGJHI_02790	7.12e-159	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMDFGJHI_02791	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HMDFGJHI_02792	1.58e-59	-	-	-	-	-	-	-	-
HMDFGJHI_02793	1.72e-135	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HMDFGJHI_02794	1.03e-65	-	-	-	-	-	-	-	-
HMDFGJHI_02795	4.16e-314	-	-	-	S	-	-	-	Putative metallopeptidase domain
HMDFGJHI_02796	4.03e-283	-	-	-	S	-	-	-	associated with various cellular activities
HMDFGJHI_02797	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HMDFGJHI_02798	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HMDFGJHI_02799	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HMDFGJHI_02800	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HMDFGJHI_02801	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HMDFGJHI_02802	4.73e-242	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HMDFGJHI_02803	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HMDFGJHI_02804	4.12e-293	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HMDFGJHI_02805	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HMDFGJHI_02806	1.45e-297	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HMDFGJHI_02807	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HMDFGJHI_02808	3.9e-143	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HMDFGJHI_02809	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HMDFGJHI_02810	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HMDFGJHI_02811	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HMDFGJHI_02812	5.14e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HMDFGJHI_02813	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMDFGJHI_02814	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HMDFGJHI_02815	1.64e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HMDFGJHI_02816	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HMDFGJHI_02817	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HMDFGJHI_02818	3.51e-252	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HMDFGJHI_02819	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HMDFGJHI_02820	8.93e-249	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HMDFGJHI_02821	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HMDFGJHI_02822	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HMDFGJHI_02823	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMDFGJHI_02824	2.2e-173	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HMDFGJHI_02825	7.89e-213	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMDFGJHI_02826	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HMDFGJHI_02827	1.4e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMDFGJHI_02828	1.2e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMDFGJHI_02829	6.68e-205	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMDFGJHI_02830	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HMDFGJHI_02831	1.12e-211	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HMDFGJHI_02832	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HMDFGJHI_02833	1.12e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HMDFGJHI_02834	2.09e-83	-	-	-	-	-	-	-	-
HMDFGJHI_02835	2.63e-200	estA	-	-	S	-	-	-	Putative esterase
HMDFGJHI_02836	3.15e-173	-	-	-	K	-	-	-	UTRA domain
HMDFGJHI_02837	1.87e-316	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMDFGJHI_02838	1.62e-207	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMDFGJHI_02839	1.69e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HMDFGJHI_02840	7.57e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HMDFGJHI_02841	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMDFGJHI_02842	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMDFGJHI_02843	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HMDFGJHI_02844	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMDFGJHI_02845	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMDFGJHI_02846	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HMDFGJHI_02847	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HMDFGJHI_02848	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HMDFGJHI_02849	3.1e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HMDFGJHI_02850	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HMDFGJHI_02851	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HMDFGJHI_02853	2.83e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMDFGJHI_02854	2.58e-186	yxeH	-	-	S	-	-	-	hydrolase
HMDFGJHI_02855	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMDFGJHI_02856	8.34e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HMDFGJHI_02857	4.66e-164	alsE	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
HMDFGJHI_02858	3.64e-224	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
HMDFGJHI_02859	6.25e-63	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMDFGJHI_02860	1.91e-98	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMDFGJHI_02861	2.28e-08	-	-	-	H	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMDFGJHI_02862	1.54e-310	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
HMDFGJHI_02863	7.47e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HMDFGJHI_02864	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HMDFGJHI_02865	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMDFGJHI_02866	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMDFGJHI_02867	2.05e-159	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HMDFGJHI_02868	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HMDFGJHI_02869	1.73e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HMDFGJHI_02870	6.83e-133	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HMDFGJHI_02871	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HMDFGJHI_02872	8.71e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HMDFGJHI_02873	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HMDFGJHI_02874	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HMDFGJHI_02875	3.44e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HMDFGJHI_02876	5.23e-160	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HMDFGJHI_02877	5.6e-292	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HMDFGJHI_02878	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HMDFGJHI_02879	1.22e-115	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HMDFGJHI_02880	1.06e-16	-	-	-	-	-	-	-	-
HMDFGJHI_02881	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HMDFGJHI_02882	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HMDFGJHI_02883	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HMDFGJHI_02884	3.67e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HMDFGJHI_02885	2.56e-261	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HMDFGJHI_02886	7.24e-23	-	-	-	-	-	-	-	-
HMDFGJHI_02887	1.48e-95	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HMDFGJHI_02888	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HMDFGJHI_02890	1.97e-256	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HMDFGJHI_02891	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMDFGJHI_02892	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HMDFGJHI_02893	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HMDFGJHI_02894	4.04e-94	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HMDFGJHI_02895	1.45e-162	-	-	-	S	-	-	-	Membrane
HMDFGJHI_02896	1.31e-210	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HMDFGJHI_02897	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
HMDFGJHI_02898	4.22e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HMDFGJHI_02899	1.17e-58	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HMDFGJHI_02900	7.24e-276	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HMDFGJHI_02901	6.57e-311	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HMDFGJHI_02902	8.35e-230	rhaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HMDFGJHI_02903	6.08e-179	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HMDFGJHI_02904	3.71e-105	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMDFGJHI_02905	3e-08	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HMDFGJHI_02906	1.86e-223	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HMDFGJHI_02908	8.74e-155	dpnM	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	Site-specific DNA-methyltransferase (adenine-specific)
HMDFGJHI_02909	3.19e-62	-	-	-	-	-	-	-	-
HMDFGJHI_02910	2.54e-31	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMDFGJHI_02911	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HMDFGJHI_02912	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HMDFGJHI_02913	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMDFGJHI_02914	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HMDFGJHI_02915	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HMDFGJHI_02916	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HMDFGJHI_02917	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HMDFGJHI_02918	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HMDFGJHI_02919	1.13e-182	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HMDFGJHI_02920	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMDFGJHI_02921	6.95e-204	degV1	-	-	S	-	-	-	DegV family
HMDFGJHI_02922	1.43e-80	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HMDFGJHI_02923	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HMDFGJHI_02925	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HMDFGJHI_02926	0.0	-	-	-	-	-	-	-	-
HMDFGJHI_02928	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HMDFGJHI_02929	3.74e-143	-	-	-	S	-	-	-	Cell surface protein
HMDFGJHI_02930	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMDFGJHI_02931	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMDFGJHI_02932	2.37e-173	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HMDFGJHI_02933	2.26e-306	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HMDFGJHI_02934	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HMDFGJHI_02935	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMDFGJHI_02936	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme