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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
LEFFLKOP_00001	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
LEFFLKOP_00002	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
LEFFLKOP_00003	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LEFFLKOP_00004	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LEFFLKOP_00005	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEFFLKOP_00006	2.47e-107	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LEFFLKOP_00007	1.62e-124	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
LEFFLKOP_00008	5.18e-276	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
LEFFLKOP_00009	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
LEFFLKOP_00010	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
LEFFLKOP_00012	9.79e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEFFLKOP_00013	3.9e-137	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LEFFLKOP_00014	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LEFFLKOP_00015	3.75e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
LEFFLKOP_00016	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LEFFLKOP_00017	4.23e-231	yaaC	-	-	S	-	-	-	YaaC-like Protein
LEFFLKOP_00018	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
LEFFLKOP_00019	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
LEFFLKOP_00020	1.2e-122	-	-	-	M	-	-	-	FR47-like protein
LEFFLKOP_00021	4.54e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
LEFFLKOP_00022	6.85e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
LEFFLKOP_00023	1.95e-109	yuaE	-	-	S	-	-	-	DinB superfamily
LEFFLKOP_00024	1.37e-135	yuaD	-	-	-	-	-	-	-
LEFFLKOP_00025	1e-290	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
LEFFLKOP_00026	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
LEFFLKOP_00027	2.39e-121	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
LEFFLKOP_00028	5.83e-118	yuaB	-	-	-	-	-	-	-
LEFFLKOP_00029	1.83e-157	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
LEFFLKOP_00030	1.85e-301	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
LEFFLKOP_00031	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
LEFFLKOP_00032	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEFFLKOP_00033	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
LEFFLKOP_00034	6.82e-114	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
LEFFLKOP_00036	6.02e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LEFFLKOP_00037	3.8e-256	yubA	-	-	S	-	-	-	transporter activity
LEFFLKOP_00038	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
LEFFLKOP_00039	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
LEFFLKOP_00040	4.94e-73	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
LEFFLKOP_00041	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LEFFLKOP_00042	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
LEFFLKOP_00043	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
LEFFLKOP_00044	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
LEFFLKOP_00045	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
LEFFLKOP_00046	1.2e-297	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
LEFFLKOP_00047	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
LEFFLKOP_00048	1.06e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
LEFFLKOP_00049	5e-48	-	-	-	-	-	-	-	-
LEFFLKOP_00050	3.63e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
LEFFLKOP_00051	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
LEFFLKOP_00052	1.07e-301	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
LEFFLKOP_00053	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
LEFFLKOP_00054	1.35e-51	-	-	-	-	-	-	-	-
LEFFLKOP_00055	2.12e-70	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
LEFFLKOP_00056	1.76e-233	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
LEFFLKOP_00057	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
LEFFLKOP_00059	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
LEFFLKOP_00060	5.34e-289	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
LEFFLKOP_00061	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
LEFFLKOP_00062	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
LEFFLKOP_00063	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
LEFFLKOP_00064	1.28e-253	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
LEFFLKOP_00065	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00066	2.72e-198	yugF	-	-	I	-	-	-	Hydrolase
LEFFLKOP_00067	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
LEFFLKOP_00068	1.16e-286	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LEFFLKOP_00069	3.04e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_00070	2.49e-91	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
LEFFLKOP_00071	1.71e-149	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
LEFFLKOP_00073	1.08e-242	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
LEFFLKOP_00074	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
LEFFLKOP_00075	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_00076	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
LEFFLKOP_00077	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
LEFFLKOP_00078	3.26e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
LEFFLKOP_00079	6.34e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
LEFFLKOP_00080	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_00081	1.29e-236	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
LEFFLKOP_00082	6.97e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
LEFFLKOP_00083	7.99e-309	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
LEFFLKOP_00084	1.73e-22	-	-	-	-	-	-	-	-
LEFFLKOP_00085	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LEFFLKOP_00086	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEFFLKOP_00087	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEFFLKOP_00088	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEFFLKOP_00089	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEFFLKOP_00090	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEFFLKOP_00091	9.92e-78	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
LEFFLKOP_00092	2.24e-82	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
LEFFLKOP_00093	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEFFLKOP_00094	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_00096	5.77e-169	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
LEFFLKOP_00097	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
LEFFLKOP_00098	8.73e-09	yuzC	-	-	-	-	-	-	-
LEFFLKOP_00099	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
LEFFLKOP_00100	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEFFLKOP_00101	3.27e-134	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
LEFFLKOP_00102	2.19e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
LEFFLKOP_00103	1.34e-51	yueH	-	-	S	-	-	-	YueH-like protein
LEFFLKOP_00104	7.15e-43	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
LEFFLKOP_00105	2.73e-244	yueF	-	-	S	-	-	-	transporter activity
LEFFLKOP_00106	6.34e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
LEFFLKOP_00107	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
LEFFLKOP_00108	1.91e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
LEFFLKOP_00109	2.38e-168	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEFFLKOP_00110	1.78e-96	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
LEFFLKOP_00111	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
LEFFLKOP_00112	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LEFFLKOP_00113	3.51e-270	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
LEFFLKOP_00114	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
LEFFLKOP_00115	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
LEFFLKOP_00116	9.9e-291	yukF	-	-	QT	-	-	-	Transcriptional regulator
LEFFLKOP_00117	1.64e-261	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
LEFFLKOP_00118	1.2e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
LEFFLKOP_00119	4.08e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
LEFFLKOP_00120	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEFFLKOP_00121	1.5e-226	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
LEFFLKOP_00122	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
LEFFLKOP_00123	7.34e-291	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
LEFFLKOP_00124	5.83e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
LEFFLKOP_00125	8.58e-211	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
LEFFLKOP_00126	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
LEFFLKOP_00127	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
LEFFLKOP_00128	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
LEFFLKOP_00129	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LEFFLKOP_00130	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
LEFFLKOP_00131	3.14e-149	yuiC	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_00132	1.14e-45	yuiB	-	-	S	-	-	-	Putative membrane protein
LEFFLKOP_00133	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
LEFFLKOP_00134	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
LEFFLKOP_00136	4.51e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEFFLKOP_00137	8.15e-149	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
LEFFLKOP_00138	3.98e-115	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEFFLKOP_00139	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
LEFFLKOP_00140	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LEFFLKOP_00141	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEFFLKOP_00142	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
LEFFLKOP_00143	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
LEFFLKOP_00144	5.44e-74	yuzD	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_00145	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
LEFFLKOP_00146	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
LEFFLKOP_00147	2.57e-221	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LEFFLKOP_00148	2.4e-253	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LEFFLKOP_00149	1.67e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
LEFFLKOP_00150	1.55e-253	yutH	-	-	S	-	-	-	Spore coat protein
LEFFLKOP_00151	3.21e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
LEFFLKOP_00152	2.49e-181	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LEFFLKOP_00153	2.38e-99	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
LEFFLKOP_00154	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_00155	5.47e-144	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEFFLKOP_00156	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LEFFLKOP_00157	3.11e-251	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
LEFFLKOP_00158	2.46e-171	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
LEFFLKOP_00159	3.41e-65	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
LEFFLKOP_00160	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
LEFFLKOP_00161	6.51e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
LEFFLKOP_00162	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
LEFFLKOP_00163	2.72e-82	yunG	-	-	-	-	-	-	-
LEFFLKOP_00164	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LEFFLKOP_00165	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
LEFFLKOP_00166	2.82e-298	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
LEFFLKOP_00167	8.71e-281	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
LEFFLKOP_00168	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
LEFFLKOP_00169	2.01e-70	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
LEFFLKOP_00170	5.71e-121	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LEFFLKOP_00171	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LEFFLKOP_00172	6.5e-183	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LEFFLKOP_00173	4.18e-141	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
LEFFLKOP_00174	3.87e-238	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LEFFLKOP_00176	8.51e-306	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LEFFLKOP_00177	1.64e-301	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LEFFLKOP_00178	1.8e-215	bsn	-	-	L	-	-	-	Ribonuclease
LEFFLKOP_00179	2.42e-262	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
LEFFLKOP_00180	7.46e-176	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
LEFFLKOP_00181	5.31e-206	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
LEFFLKOP_00182	4.58e-215	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
LEFFLKOP_00183	3.54e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
LEFFLKOP_00184	5.79e-307	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
LEFFLKOP_00185	5.27e-235	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LEFFLKOP_00186	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
LEFFLKOP_00187	4.36e-263	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
LEFFLKOP_00189	3.35e-56	-	-	-	-	-	-	-	-
LEFFLKOP_00190	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
LEFFLKOP_00191	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
LEFFLKOP_00192	3.99e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LEFFLKOP_00193	7.43e-313	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
LEFFLKOP_00194	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LEFFLKOP_00195	5.44e-81	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LEFFLKOP_00196	2.91e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
LEFFLKOP_00197	2.64e-125	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
LEFFLKOP_00198	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEFFLKOP_00199	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
LEFFLKOP_00200	5.73e-73	yusE	-	-	CO	-	-	-	Thioredoxin
LEFFLKOP_00201	7.62e-97	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
LEFFLKOP_00202	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
LEFFLKOP_00203	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LEFFLKOP_00204	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
LEFFLKOP_00205	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
LEFFLKOP_00206	1.34e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
LEFFLKOP_00207	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
LEFFLKOP_00208	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
LEFFLKOP_00209	2.84e-210	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
LEFFLKOP_00210	2.23e-54	-	-	-	-	-	-	-	-
LEFFLKOP_00211	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
LEFFLKOP_00212	4.47e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
LEFFLKOP_00213	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
LEFFLKOP_00214	2.93e-85	yusQ	-	-	S	-	-	-	Tautomerase enzyme
LEFFLKOP_00215	8.6e-139	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
LEFFLKOP_00216	8.42e-204	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
LEFFLKOP_00217	3.66e-64	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
LEFFLKOP_00218	1.06e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
LEFFLKOP_00219	2.86e-87	-	-	-	S	-	-	-	YusW-like protein
LEFFLKOP_00220	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
LEFFLKOP_00221	1.1e-196	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
LEFFLKOP_00222	8.76e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
LEFFLKOP_00223	5.56e-305	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEFFLKOP_00224	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEFFLKOP_00225	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_00226	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00227	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LEFFLKOP_00228	4.48e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
LEFFLKOP_00229	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
LEFFLKOP_00230	2.9e-253	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
LEFFLKOP_00231	3.48e-249	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
LEFFLKOP_00232	9.39e-141	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEFFLKOP_00233	4.06e-246	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_00234	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
LEFFLKOP_00235	6.57e-178	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
LEFFLKOP_00236	4.22e-144	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LEFFLKOP_00237	2.18e-56	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
LEFFLKOP_00238	3.91e-05	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
LEFFLKOP_00239	1.13e-288	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_00240	8.21e-133	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
LEFFLKOP_00241	3.76e-316	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LEFFLKOP_00242	6.35e-235	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEFFLKOP_00243	1.72e-217	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
LEFFLKOP_00244	1.23e-180	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
LEFFLKOP_00245	2.67e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
LEFFLKOP_00246	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
LEFFLKOP_00247	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEFFLKOP_00248	6.16e-33	-	-	-	-	-	-	-	-
LEFFLKOP_00249	5.77e-127	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
LEFFLKOP_00250	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
LEFFLKOP_00251	9.23e-292	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
LEFFLKOP_00252	1.16e-84	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
LEFFLKOP_00253	3.36e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
LEFFLKOP_00254	4.64e-159	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_00255	6.94e-229	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
LEFFLKOP_00257	9.78e-190	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
LEFFLKOP_00258	9.64e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEFFLKOP_00259	1.21e-236	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEFFLKOP_00260	1.09e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEFFLKOP_00261	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
LEFFLKOP_00262	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
LEFFLKOP_00263	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
LEFFLKOP_00264	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
LEFFLKOP_00265	5.98e-213	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
LEFFLKOP_00266	2.11e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
LEFFLKOP_00267	1.95e-150	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
LEFFLKOP_00268	6.19e-201	yvgN	-	-	S	-	-	-	reductase
LEFFLKOP_00269	7.97e-113	yvgO	-	-	-	-	-	-	-
LEFFLKOP_00270	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
LEFFLKOP_00271	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LEFFLKOP_00272	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LEFFLKOP_00273	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
LEFFLKOP_00275	2.34e-139	yvgT	-	-	S	-	-	-	membrane
LEFFLKOP_00276	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
LEFFLKOP_00277	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
LEFFLKOP_00278	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
LEFFLKOP_00279	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
LEFFLKOP_00280	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
LEFFLKOP_00281	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
LEFFLKOP_00282	1.71e-248	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
LEFFLKOP_00283	2.08e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LEFFLKOP_00284	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
LEFFLKOP_00285	2.02e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
LEFFLKOP_00286	3.52e-71	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
LEFFLKOP_00287	1.17e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEFFLKOP_00288	9.32e-181	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
LEFFLKOP_00290	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LEFFLKOP_00291	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LEFFLKOP_00292	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
LEFFLKOP_00293	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
LEFFLKOP_00294	4.03e-196	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
LEFFLKOP_00295	3.44e-48	yvzC	-	-	K	-	-	-	transcriptional
LEFFLKOP_00296	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
LEFFLKOP_00297	1.19e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
LEFFLKOP_00298	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
LEFFLKOP_00299	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
LEFFLKOP_00300	2.26e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
LEFFLKOP_00301	3.37e-220	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LEFFLKOP_00302	1.55e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
LEFFLKOP_00303	1e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LEFFLKOP_00304	6.63e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
LEFFLKOP_00305	9.67e-137	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
LEFFLKOP_00306	1.74e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LEFFLKOP_00307	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
LEFFLKOP_00308	5.58e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LEFFLKOP_00309	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
LEFFLKOP_00310	7.95e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
LEFFLKOP_00311	9.9e-144	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
LEFFLKOP_00312	1.61e-156	yvbI	-	-	M	-	-	-	Membrane
LEFFLKOP_00313	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
LEFFLKOP_00314	6.87e-106	yvbK	-	-	K	-	-	-	acetyltransferase
LEFFLKOP_00315	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEFFLKOP_00316	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
LEFFLKOP_00317	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEFFLKOP_00318	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
LEFFLKOP_00319	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEFFLKOP_00320	6.64e-235	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LEFFLKOP_00321	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEFFLKOP_00322	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
LEFFLKOP_00323	1.04e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEFFLKOP_00325	5.49e-205	yvbU	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00326	7.93e-198	yvbV	-	-	EG	-	-	-	EamA-like transporter family
LEFFLKOP_00327	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
LEFFLKOP_00328	3e-249	-	-	-	S	-	-	-	Glycosyl hydrolase
LEFFLKOP_00329	5.89e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LEFFLKOP_00330	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LEFFLKOP_00331	1.06e-173	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LEFFLKOP_00332	4.36e-136	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEFFLKOP_00333	1.76e-257	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_00334	4.81e-169	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
LEFFLKOP_00335	5.95e-209	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
LEFFLKOP_00336	7.25e-201	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
LEFFLKOP_00337	1.52e-265	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
LEFFLKOP_00338	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
LEFFLKOP_00339	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
LEFFLKOP_00340	3.82e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
LEFFLKOP_00341	1.3e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
LEFFLKOP_00342	2.05e-295	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
LEFFLKOP_00343	6.42e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_00344	6.85e-146	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
LEFFLKOP_00345	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
LEFFLKOP_00346	2.57e-308	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LEFFLKOP_00347	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
LEFFLKOP_00348	1.85e-241	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
LEFFLKOP_00349	4.89e-284	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
LEFFLKOP_00350	6.53e-81	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
LEFFLKOP_00351	1.65e-141	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LEFFLKOP_00352	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEFFLKOP_00353	1.53e-242	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
LEFFLKOP_00354	1.03e-263	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
LEFFLKOP_00355	3.5e-248	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
LEFFLKOP_00356	3.59e-264	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
LEFFLKOP_00357	5.9e-277	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
LEFFLKOP_00358	1.25e-201	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
LEFFLKOP_00359	4.69e-283	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
LEFFLKOP_00360	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
LEFFLKOP_00361	7.94e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
LEFFLKOP_00362	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
LEFFLKOP_00363	3.57e-98	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
LEFFLKOP_00364	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
LEFFLKOP_00366	3.13e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
LEFFLKOP_00367	7.42e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
LEFFLKOP_00368	2.06e-161	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
LEFFLKOP_00369	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
LEFFLKOP_00370	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
LEFFLKOP_00371	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
LEFFLKOP_00372	0.0	ybeC	-	-	E	-	-	-	amino acid
LEFFLKOP_00373	1.17e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00374	2.57e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
LEFFLKOP_00375	1.03e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
LEFFLKOP_00376	5.53e-122	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
LEFFLKOP_00377	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
LEFFLKOP_00378	9.45e-234	-	-	-	S	-	-	-	Patatin-like phospholipase
LEFFLKOP_00380	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LEFFLKOP_00381	4.09e-151	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
LEFFLKOP_00382	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
LEFFLKOP_00383	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
LEFFLKOP_00384	1.14e-196	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
LEFFLKOP_00385	6.84e-190	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
LEFFLKOP_00386	1.43e-309	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
LEFFLKOP_00387	9.87e-301	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
LEFFLKOP_00388	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
LEFFLKOP_00389	1.54e-221	yvdE	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00390	2.66e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
LEFFLKOP_00391	7.84e-71	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
LEFFLKOP_00392	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
LEFFLKOP_00393	3.73e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
LEFFLKOP_00394	1.15e-234	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEFFLKOP_00395	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
LEFFLKOP_00396	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_00397	1.32e-249	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
LEFFLKOP_00398	4.67e-172	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEFFLKOP_00399	1.37e-45	-	-	-	-	-	-	-	-
LEFFLKOP_00400	8.35e-185	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
LEFFLKOP_00401	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
LEFFLKOP_00402	3.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
LEFFLKOP_00403	3.88e-226	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
LEFFLKOP_00404	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
LEFFLKOP_00405	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LEFFLKOP_00406	8.31e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LEFFLKOP_00407	3.05e-190	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
LEFFLKOP_00408	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
LEFFLKOP_00409	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
LEFFLKOP_00411	0.0	-	-	-	-	-	-	-	-
LEFFLKOP_00412	5.6e-98	-	-	-	-	-	-	-	-
LEFFLKOP_00413	2.61e-146	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
LEFFLKOP_00414	9.74e-177	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LEFFLKOP_00415	1.44e-170	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LEFFLKOP_00416	7.21e-150	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LEFFLKOP_00417	4.96e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
LEFFLKOP_00418	1.19e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LEFFLKOP_00419	9.09e-149	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LEFFLKOP_00420	9.84e-281	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LEFFLKOP_00421	6.12e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
LEFFLKOP_00422	1.05e-151	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
LEFFLKOP_00423	3.58e-119	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
LEFFLKOP_00424	3.05e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LEFFLKOP_00425	2.51e-209	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
LEFFLKOP_00426	2.61e-194	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LEFFLKOP_00427	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LEFFLKOP_00428	2.41e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LEFFLKOP_00429	1.37e-162	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LEFFLKOP_00430	5.23e-172	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
LEFFLKOP_00431	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
LEFFLKOP_00432	4.06e-94	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
LEFFLKOP_00433	2.45e-288	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
LEFFLKOP_00434	8.35e-176	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
LEFFLKOP_00435	1.03e-112	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
LEFFLKOP_00436	4.26e-272	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
LEFFLKOP_00437	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
LEFFLKOP_00438	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
LEFFLKOP_00439	9.59e-220	yvlB	-	-	S	-	-	-	Putative adhesin
LEFFLKOP_00440	3.3e-64	yvlA	-	-	-	-	-	-	-
LEFFLKOP_00441	2.25e-45	yvkN	-	-	-	-	-	-	-
LEFFLKOP_00442	3.5e-102	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LEFFLKOP_00443	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LEFFLKOP_00444	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LEFFLKOP_00445	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_00446	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
LEFFLKOP_00447	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00448	1.23e-294	yvkA	-	-	P	-	-	-	-transporter
LEFFLKOP_00449	3.17e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEFFLKOP_00450	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
LEFFLKOP_00451	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
LEFFLKOP_00452	5.45e-199	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LEFFLKOP_00453	1.5e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
LEFFLKOP_00454	4.42e-73	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
LEFFLKOP_00455	1.53e-183	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
LEFFLKOP_00456	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LEFFLKOP_00457	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LEFFLKOP_00458	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LEFFLKOP_00459	7.52e-87	-	-	-	-	-	-	-	-
LEFFLKOP_00460	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
LEFFLKOP_00461	5.15e-91	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
LEFFLKOP_00462	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LEFFLKOP_00463	1.1e-76	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
LEFFLKOP_00464	8.01e-202	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LEFFLKOP_00465	3.02e-40	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LEFFLKOP_00466	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LEFFLKOP_00467	3.99e-91	yviE	-	-	-	-	-	-	-
LEFFLKOP_00468	3.8e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
LEFFLKOP_00469	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
LEFFLKOP_00470	8.25e-101	yvyG	-	-	NOU	-	-	-	FlgN protein
LEFFLKOP_00471	4.32e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
LEFFLKOP_00472	1.83e-96	yvyF	-	-	S	-	-	-	flagellar protein
LEFFLKOP_00473	1.07e-160	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
LEFFLKOP_00474	4.22e-60	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
LEFFLKOP_00475	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LEFFLKOP_00476	2.15e-199	degV	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_00477	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEFFLKOP_00478	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LEFFLKOP_00479	2.41e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
LEFFLKOP_00480	1.43e-224	yvhJ	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00481	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LEFFLKOP_00482	3.4e-296	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
LEFFLKOP_00483	8.42e-187	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
LEFFLKOP_00484	5.79e-147	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
LEFFLKOP_00485	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
LEFFLKOP_00486	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEFFLKOP_00487	4.66e-278	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
LEFFLKOP_00488	2.58e-316	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEFFLKOP_00489	1.49e-143	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LEFFLKOP_00490	9e-109	-	-	-	M	-	-	-	Glycosyltransferase like family 2
LEFFLKOP_00491	2.61e-264	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
LEFFLKOP_00492	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
LEFFLKOP_00493	4.58e-16	-	-	-	-	-	-	-	-
LEFFLKOP_00494	1.16e-211	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LEFFLKOP_00495	2.21e-276	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LEFFLKOP_00496	1.48e-103	-	-	-	M	-	-	-	Glycosyltransferase like family 2
LEFFLKOP_00497	5.45e-117	-	-	-	M	-	-	-	Glycosyl transferases group 1
LEFFLKOP_00499	2.74e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
LEFFLKOP_00500	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LEFFLKOP_00501	1.37e-167	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
LEFFLKOP_00502	3.96e-102	-	-	-	-	-	-	-	-
LEFFLKOP_00503	5.37e-68	-	-	-	-	-	-	-	-
LEFFLKOP_00504	1.52e-248	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LEFFLKOP_00505	2.07e-106	-	-	-	M	-	-	-	Glycosyltransferase like family 2
LEFFLKOP_00506	6.53e-180	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LEFFLKOP_00507	1.32e-73	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
LEFFLKOP_00508	6.82e-111	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LEFFLKOP_00509	1.01e-129	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LEFFLKOP_00510	1.46e-134	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
LEFFLKOP_00511	5.68e-186	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
LEFFLKOP_00512	6.69e-110	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	M	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LEFFLKOP_00513	1.42e-235	tarL	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LEFFLKOP_00514	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEFFLKOP_00515	9.14e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
LEFFLKOP_00516	3.12e-310	gerBA	-	-	EG	ko:K06291,ko:K06310	-	ko00000	Spore germination protein
LEFFLKOP_00517	3.4e-238	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
LEFFLKOP_00518	1.95e-251	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
LEFFLKOP_00519	2.27e-315	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEFFLKOP_00520	1.42e-220	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00521	4.69e-201	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
LEFFLKOP_00522	1.37e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LEFFLKOP_00523	2.29e-29	ywtC	-	-	-	-	-	-	-
LEFFLKOP_00524	1.1e-276	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LEFFLKOP_00525	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
LEFFLKOP_00526	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
LEFFLKOP_00527	2.68e-227	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
LEFFLKOP_00528	7.52e-206	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEFFLKOP_00529	3.24e-84	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LEFFLKOP_00530	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LEFFLKOP_00531	3.35e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
LEFFLKOP_00532	6.09e-202	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
LEFFLKOP_00533	6.59e-118	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
LEFFLKOP_00534	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
LEFFLKOP_00535	8.76e-126	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
LEFFLKOP_00536	1.84e-187	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
LEFFLKOP_00537	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
LEFFLKOP_00538	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
LEFFLKOP_00539	1.68e-281	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LEFFLKOP_00540	2.5e-161	ywrJ	-	-	-	-	-	-	-
LEFFLKOP_00541	1.37e-194	cotB	-	-	-	ko:K06325	-	ko00000	-
LEFFLKOP_00542	2.64e-268	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
LEFFLKOP_00543	2.17e-16	-	-	-	-	-	-	-	-
LEFFLKOP_00544	1.77e-142	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LEFFLKOP_00545	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
LEFFLKOP_00546	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
LEFFLKOP_00547	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
LEFFLKOP_00548	6.44e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
LEFFLKOP_00549	3.51e-113	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
LEFFLKOP_00551	6.11e-129	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
LEFFLKOP_00552	3.33e-209	-	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00553	8.51e-155	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LEFFLKOP_00554	1.13e-126	-	-	-	-	-	-	-	-
LEFFLKOP_00556	2.2e-66	-	-	-	-	-	-	-	-
LEFFLKOP_00557	1.29e-97	-	-	-	-	-	-	-	-
LEFFLKOP_00558	1.95e-297	ywqJ	-	-	S	-	-	-	Pre-toxin TG
LEFFLKOP_00559	4.98e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
LEFFLKOP_00561	1.71e-195	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
LEFFLKOP_00562	1.34e-312	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEFFLKOP_00563	1.18e-178	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
LEFFLKOP_00564	1.06e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
LEFFLKOP_00565	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
LEFFLKOP_00566	3.6e-25	-	-	-	-	-	-	-	-
LEFFLKOP_00567	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
LEFFLKOP_00568	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
LEFFLKOP_00569	1.45e-199	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
LEFFLKOP_00570	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
LEFFLKOP_00571	1.04e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
LEFFLKOP_00572	3.56e-86	ywpG	-	-	-	-	-	-	-
LEFFLKOP_00573	3.59e-88	ywpF	-	-	S	-	-	-	YwpF-like protein
LEFFLKOP_00574	6.34e-66	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
LEFFLKOP_00575	2.51e-18	-	-	-	M	-	-	-	cell wall anchor domain
LEFFLKOP_00576	1.28e-66	ywpD	-	-	T	-	-	-	Histidine kinase
LEFFLKOP_00577	1.13e-79	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LEFFLKOP_00578	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEFFLKOP_00579	5.45e-257	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
LEFFLKOP_00580	4.1e-182	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
LEFFLKOP_00581	6.18e-173	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
LEFFLKOP_00582	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
LEFFLKOP_00583	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
LEFFLKOP_00584	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
LEFFLKOP_00585	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_00586	2.92e-312	ywoF	-	-	P	-	-	-	Right handed beta helix region
LEFFLKOP_00587	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
LEFFLKOP_00588	8e-309	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
LEFFLKOP_00589	2.56e-134	yjgF	-	-	Q	-	-	-	Isochorismatase family
LEFFLKOP_00590	4.15e-100	-	-	-	-	-	-	-	-
LEFFLKOP_00591	1.6e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
LEFFLKOP_00592	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
LEFFLKOP_00593	6.02e-135	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
LEFFLKOP_00594	1.63e-95	ywnJ	-	-	S	-	-	-	VanZ like family
LEFFLKOP_00595	2.13e-175	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
LEFFLKOP_00596	1.55e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
LEFFLKOP_00597	3.28e-22	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
LEFFLKOP_00598	7.07e-92	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
LEFFLKOP_00599	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEFFLKOP_00600	3.82e-181	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
LEFFLKOP_00601	1.24e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
LEFFLKOP_00602	1.02e-145	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
LEFFLKOP_00603	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00604	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LEFFLKOP_00605	1.12e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
LEFFLKOP_00606	1.94e-66	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
LEFFLKOP_00608	1.11e-21	csbD	-	-	K	-	-	-	CsbD-like
LEFFLKOP_00609	7.7e-110	ywmF	-	-	S	-	-	-	Peptidase M50
LEFFLKOP_00611	6.22e-129	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
LEFFLKOP_00612	2.65e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LEFFLKOP_00613	2.22e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LEFFLKOP_00615	1.44e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
LEFFLKOP_00616	1.56e-156	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
LEFFLKOP_00617	3.41e-234	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
LEFFLKOP_00618	1e-305	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEFFLKOP_00619	2.68e-171	ywmB	-	-	S	-	-	-	TATA-box binding
LEFFLKOP_00620	4.54e-45	ywzB	-	-	S	-	-	-	membrane
LEFFLKOP_00621	4.84e-112	ywmA	-	-	-	-	-	-	-
LEFFLKOP_00622	2.44e-75	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
LEFFLKOP_00623	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LEFFLKOP_00624	4.46e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LEFFLKOP_00625	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LEFFLKOP_00626	9.66e-117	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEFFLKOP_00627	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LEFFLKOP_00628	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEFFLKOP_00629	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
LEFFLKOP_00630	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
LEFFLKOP_00631	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LEFFLKOP_00632	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LEFFLKOP_00633	2.9e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
LEFFLKOP_00634	1.36e-105	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
LEFFLKOP_00635	1.58e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEFFLKOP_00636	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
LEFFLKOP_00637	1.22e-249	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LEFFLKOP_00638	1.04e-99	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
LEFFLKOP_00639	1.55e-150	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
LEFFLKOP_00640	5.61e-73	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
LEFFLKOP_00642	2.42e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LEFFLKOP_00643	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LEFFLKOP_00644	4.84e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEFFLKOP_00645	6.01e-117	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LEFFLKOP_00646	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
LEFFLKOP_00647	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
LEFFLKOP_00648	9.96e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
LEFFLKOP_00649	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
LEFFLKOP_00650	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LEFFLKOP_00651	2.03e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
LEFFLKOP_00652	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEFFLKOP_00653	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LEFFLKOP_00654	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
LEFFLKOP_00655	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
LEFFLKOP_00656	1.91e-119	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
LEFFLKOP_00657	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LEFFLKOP_00658	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LEFFLKOP_00659	1.58e-264	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
LEFFLKOP_00660	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
LEFFLKOP_00661	8.56e-290	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LEFFLKOP_00662	2.32e-234	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LEFFLKOP_00663	1.32e-57	ywjC	-	-	-	-	-	-	-
LEFFLKOP_00664	2.08e-117	ywjB	-	-	H	-	-	-	RibD C-terminal domain
LEFFLKOP_00665	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
LEFFLKOP_00666	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEFFLKOP_00667	4.85e-158	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
LEFFLKOP_00668	7.94e-122	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
LEFFLKOP_00669	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
LEFFLKOP_00670	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEFFLKOP_00671	5.02e-110	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
LEFFLKOP_00672	1.84e-179	ywiC	-	-	S	-	-	-	YwiC-like protein
LEFFLKOP_00673	3.98e-169	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
LEFFLKOP_00674	1.2e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
LEFFLKOP_00675	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
LEFFLKOP_00676	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_00677	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
LEFFLKOP_00678	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
LEFFLKOP_00680	1.5e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
LEFFLKOP_00681	5.67e-296	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
LEFFLKOP_00682	4.88e-276	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
LEFFLKOP_00683	2.34e-315	-	-	-	L	-	-	-	Peptidase, M16
LEFFLKOP_00685	2.71e-314	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
LEFFLKOP_00686	1.41e-276	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
LEFFLKOP_00687	1.64e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
LEFFLKOP_00689	5.24e-52	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
LEFFLKOP_00690	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
LEFFLKOP_00691	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LEFFLKOP_00692	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
LEFFLKOP_00693	5.51e-123	ywhD	-	-	S	-	-	-	YwhD family
LEFFLKOP_00694	5.45e-153	ywhC	-	-	S	-	-	-	Peptidase family M50
LEFFLKOP_00695	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
LEFFLKOP_00696	1.45e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00697	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEFFLKOP_00699	6.67e-301	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
LEFFLKOP_00700	9.03e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00701	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
LEFFLKOP_00702	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
LEFFLKOP_00703	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
LEFFLKOP_00704	1.88e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
LEFFLKOP_00705	1.57e-204	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
LEFFLKOP_00706	2.15e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LEFFLKOP_00707	1.25e-207	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_00708	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
LEFFLKOP_00709	3.43e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
LEFFLKOP_00710	1.67e-176	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
LEFFLKOP_00711	1.82e-296	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
LEFFLKOP_00712	1.31e-266	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
LEFFLKOP_00713	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LEFFLKOP_00714	3.14e-178	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEFFLKOP_00715	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LEFFLKOP_00716	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LEFFLKOP_00717	1.89e-275	ywfA	-	-	EGP	-	-	-	-transporter
LEFFLKOP_00718	7.08e-316	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
LEFFLKOP_00719	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
LEFFLKOP_00720	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
LEFFLKOP_00721	5.19e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
LEFFLKOP_00722	1.51e-100	-	-	-	-	-	-	-	-
LEFFLKOP_00723	9.16e-114	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
LEFFLKOP_00724	1.41e-205	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LEFFLKOP_00725	1.51e-232	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LEFFLKOP_00726	7.45e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LEFFLKOP_00727	2.84e-240	spsG	-	-	M	-	-	-	Spore Coat
LEFFLKOP_00728	1.28e-166	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
LEFFLKOP_00729	3.93e-271	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
LEFFLKOP_00730	1.72e-209	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
LEFFLKOP_00731	3.73e-284	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
LEFFLKOP_00732	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
LEFFLKOP_00733	8.08e-187	spsA	-	-	M	-	-	-	Spore Coat
LEFFLKOP_00734	3.62e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LEFFLKOP_00735	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
LEFFLKOP_00736	1.86e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
LEFFLKOP_00737	9.23e-65	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
LEFFLKOP_00738	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
LEFFLKOP_00739	9.47e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LEFFLKOP_00740	4.68e-192	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
LEFFLKOP_00741	2.21e-187	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
LEFFLKOP_00742	6.19e-39	ywdA	-	-	-	-	-	-	-
LEFFLKOP_00743	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
LEFFLKOP_00744	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFFLKOP_00745	8e-178	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
LEFFLKOP_00746	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
LEFFLKOP_00748	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
LEFFLKOP_00749	1.4e-237	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEFFLKOP_00750	2.31e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
LEFFLKOP_00751	1.26e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
LEFFLKOP_00752	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
LEFFLKOP_00753	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
LEFFLKOP_00754	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
LEFFLKOP_00755	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LEFFLKOP_00756	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LEFFLKOP_00757	5.11e-49	ydaS	-	-	S	-	-	-	membrane
LEFFLKOP_00758	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
LEFFLKOP_00759	1.12e-290	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LEFFLKOP_00760	2.25e-75	gtcA	-	-	S	-	-	-	GtrA-like protein
LEFFLKOP_00761	3.42e-158	ywcC	-	-	K	-	-	-	transcriptional regulator
LEFFLKOP_00763	2.91e-62	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
LEFFLKOP_00764	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEFFLKOP_00765	1.03e-143	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
LEFFLKOP_00766	2.54e-307	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
LEFFLKOP_00767	1.4e-245	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
LEFFLKOP_00768	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
LEFFLKOP_00769	1.74e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LEFFLKOP_00770	3.79e-184	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LEFFLKOP_00771	2.7e-203	ywbI	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00772	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LEFFLKOP_00773	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
LEFFLKOP_00774	2.49e-276	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
LEFFLKOP_00775	3.13e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
LEFFLKOP_00776	2.31e-279	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
LEFFLKOP_00777	4.01e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
LEFFLKOP_00778	7.71e-122	-	-	-	N	-	-	-	domain, Protein
LEFFLKOP_00779	4.33e-162	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
LEFFLKOP_00780	9.36e-317	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEFFLKOP_00781	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
LEFFLKOP_00782	2.79e-310	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFFLKOP_00783	2.6e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
LEFFLKOP_00784	2.19e-215	gspA	-	-	M	-	-	-	General stress
LEFFLKOP_00785	1.22e-158	ywaF	-	-	S	-	-	-	Integral membrane protein
LEFFLKOP_00786	3.57e-114	ywaE	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00787	1.5e-295	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEFFLKOP_00788	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
LEFFLKOP_00789	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
LEFFLKOP_00790	5.1e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
LEFFLKOP_00791	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEFFLKOP_00792	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
LEFFLKOP_00793	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEFFLKOP_00794	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LEFFLKOP_00795	2.39e-177	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
LEFFLKOP_00796	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
LEFFLKOP_00797	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LEFFLKOP_00798	1.58e-50	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFFLKOP_00799	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEFFLKOP_00800	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
LEFFLKOP_00801	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
LEFFLKOP_00802	8.94e-28	yxzF	-	-	-	-	-	-	-
LEFFLKOP_00803	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
LEFFLKOP_00804	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
LEFFLKOP_00805	3.02e-275	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
LEFFLKOP_00806	3.96e-179	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LEFFLKOP_00807	1.21e-212	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_00808	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
LEFFLKOP_00809	1.75e-43	-	-	-	-	-	-	-	-
LEFFLKOP_00810	4.05e-64	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
LEFFLKOP_00811	9.06e-125	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
LEFFLKOP_00812	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
LEFFLKOP_00813	2.01e-206	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LEFFLKOP_00814	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
LEFFLKOP_00815	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
LEFFLKOP_00816	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
LEFFLKOP_00817	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
LEFFLKOP_00818	3.97e-310	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
LEFFLKOP_00819	0.0	-	-	-	O	-	-	-	Peptidase family M48
LEFFLKOP_00821	1.58e-200	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
LEFFLKOP_00822	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
LEFFLKOP_00823	1.16e-211	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
LEFFLKOP_00824	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEFFLKOP_00825	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEFFLKOP_00826	6.41e-181	-	-	-	-	-	-	-	-
LEFFLKOP_00827	3e-249	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
LEFFLKOP_00828	3.13e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
LEFFLKOP_00829	3.76e-256	-	-	-	T	-	-	-	Signal transduction histidine kinase
LEFFLKOP_00830	1.23e-144	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
LEFFLKOP_00831	7.76e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
LEFFLKOP_00833	4.98e-112	yxjI	-	-	S	-	-	-	LURP-one-related
LEFFLKOP_00834	3.53e-276	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
LEFFLKOP_00835	1.49e-273	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
LEFFLKOP_00836	1.67e-175	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LEFFLKOP_00837	5.91e-151	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LEFFLKOP_00838	5.43e-167	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LEFFLKOP_00839	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
LEFFLKOP_00840	2.79e-191	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
LEFFLKOP_00842	4.94e-268	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEFFLKOP_00843	9.87e-132	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
LEFFLKOP_00844	2.28e-63	yxiS	-	-	-	-	-	-	-
LEFFLKOP_00845	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
LEFFLKOP_00846	5.73e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
LEFFLKOP_00847	1.77e-183	bglS	-	-	M	-	-	-	licheninase activity
LEFFLKOP_00848	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
LEFFLKOP_00849	9.2e-144	-	-	-	-	-	-	-	-
LEFFLKOP_00850	7.67e-292	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
LEFFLKOP_00851	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LEFFLKOP_00852	3.67e-276	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
LEFFLKOP_00855	4.75e-57	yxiJ	-	-	S	-	-	-	YxiJ-like protein
LEFFLKOP_00856	7.97e-118	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
LEFFLKOP_00857	5.69e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
LEFFLKOP_00858	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
LEFFLKOP_00859	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
LEFFLKOP_00860	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFFLKOP_00861	8.25e-69	-	-	-	-	-	-	-	-
LEFFLKOP_00862	2.97e-274	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
LEFFLKOP_00863	1.33e-52	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
LEFFLKOP_00864	1.78e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
LEFFLKOP_00865	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
LEFFLKOP_00866	7.02e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
LEFFLKOP_00867	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
LEFFLKOP_00868	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LEFFLKOP_00869	1.64e-301	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
LEFFLKOP_00870	4.85e-231	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LEFFLKOP_00871	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
LEFFLKOP_00872	8.11e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
LEFFLKOP_00873	2.72e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEFFLKOP_00874	8.3e-150	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LEFFLKOP_00875	4.26e-222	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LEFFLKOP_00876	4.33e-196	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
LEFFLKOP_00877	2.46e-46	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
LEFFLKOP_00878	2.06e-76	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
LEFFLKOP_00879	2.21e-255	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
LEFFLKOP_00880	5.66e-312	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
LEFFLKOP_00881	5.82e-272	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
LEFFLKOP_00882	9.69e-171	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_00883	3e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
LEFFLKOP_00884	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
LEFFLKOP_00885	1.54e-121	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEFFLKOP_00886	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEFFLKOP_00887	1.71e-240	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
LEFFLKOP_00888	1.4e-194	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
LEFFLKOP_00891	7.32e-42	yxeE	-	-	-	-	-	-	-
LEFFLKOP_00892	7.57e-28	yxeD	-	-	-	-	-	-	-
LEFFLKOP_00893	6.79e-91	-	-	-	-	-	-	-	-
LEFFLKOP_00894	3.01e-226	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEFFLKOP_00895	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
LEFFLKOP_00896	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
LEFFLKOP_00897	9.39e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_00898	4e-233	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_00899	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEFFLKOP_00900	6.95e-205	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LEFFLKOP_00901	2.19e-186	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LEFFLKOP_00902	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
LEFFLKOP_00903	2.57e-250	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LEFFLKOP_00904	1.99e-296	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
LEFFLKOP_00905	4.27e-223	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LEFFLKOP_00906	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LEFFLKOP_00907	1.75e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LEFFLKOP_00908	1.64e-198	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LEFFLKOP_00909	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEFFLKOP_00910	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
LEFFLKOP_00911	3.52e-224	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
LEFFLKOP_00913	2.13e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
LEFFLKOP_00914	1.77e-314	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEFFLKOP_00915	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
LEFFLKOP_00917	8.38e-193	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
LEFFLKOP_00918	2.54e-266	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEFFLKOP_00919	7.19e-315	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
LEFFLKOP_00920	1.67e-13	-	-	-	S	-	-	-	RDD family
LEFFLKOP_00921	8.6e-136	yxaL	-	-	S	-	-	-	PQQ-like domain
LEFFLKOP_00922	2.78e-83	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
LEFFLKOP_00923	4.03e-99	yxaI	-	-	S	-	-	-	membrane protein domain
LEFFLKOP_00924	4.89e-282	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
LEFFLKOP_00925	5.8e-248	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
LEFFLKOP_00926	2.75e-130	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
LEFFLKOP_00927	5.01e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
LEFFLKOP_00928	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
LEFFLKOP_00929	5.96e-77	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
LEFFLKOP_00930	7.33e-152	yxaC	-	-	M	-	-	-	effector of murein hydrolase
LEFFLKOP_00931	7.3e-245	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
LEFFLKOP_00932	1.64e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
LEFFLKOP_00933	4.42e-164	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
LEFFLKOP_00934	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
LEFFLKOP_00935	2.05e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
LEFFLKOP_00936	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LEFFLKOP_00937	2.68e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
LEFFLKOP_00938	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
LEFFLKOP_00939	1.11e-237	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
LEFFLKOP_00940	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
LEFFLKOP_00941	7.55e-44	-	2.7.1.199	-	G	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
LEFFLKOP_00942	5.21e-164	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_00943	1.44e-24	-	-	-	-	-	-	-	-
LEFFLKOP_00944	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
LEFFLKOP_00945	2.37e-94	-	-	-	J	-	-	-	COG0617 tRNA nucleotidyltransferase poly(A) polymerase
LEFFLKOP_00946	2.66e-262	-	-	-	S	-	-	-	Protein of unknown function DUF262
LEFFLKOP_00947	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
LEFFLKOP_00948	2.99e-127	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
LEFFLKOP_00949	4.45e-156	-	-	-	L	-	-	-	Recombinase
LEFFLKOP_00950	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LEFFLKOP_00952	5.95e-92	-	-	-	-	-	-	-	-
LEFFLKOP_00953	1.81e-297	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LEFFLKOP_00955	5.5e-42	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
LEFFLKOP_00956	8.1e-262	yycP	-	-	-	-	-	-	-
LEFFLKOP_00957	9.7e-169	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LEFFLKOP_00958	5.04e-109	yycN	-	-	K	-	-	-	Acetyltransferase
LEFFLKOP_00959	5.02e-238	-	-	-	S	-	-	-	aspartate phosphatase
LEFFLKOP_00961	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
LEFFLKOP_00962	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
LEFFLKOP_00963	9.1e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
LEFFLKOP_00964	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LEFFLKOP_00965	5.27e-214	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
LEFFLKOP_00966	2.36e-122	-	-	-	K	ko:K02483	-	ko00000,ko02022	PFAM response regulator receiver
LEFFLKOP_00967	2.01e-99	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
LEFFLKOP_00968	1.97e-43	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
LEFFLKOP_00969	1.28e-276	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEFFLKOP_00970	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LEFFLKOP_00971	1.99e-199	yycI	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_00972	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_00973	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_00974	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEFFLKOP_00979	1.29e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LEFFLKOP_00980	3.29e-99	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEFFLKOP_00981	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
LEFFLKOP_00982	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
LEFFLKOP_00984	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
LEFFLKOP_00985	9.87e-282	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
LEFFLKOP_00986	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LEFFLKOP_00987	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
LEFFLKOP_00988	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
LEFFLKOP_00989	8.66e-204	yybS	-	-	S	-	-	-	membrane
LEFFLKOP_00991	6.83e-109	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
LEFFLKOP_00992	6.43e-88	yybR	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_00993	4.89e-210	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
LEFFLKOP_00994	1.3e-89	-	-	-	-	-	-	-	-
LEFFLKOP_00996	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_00997	4.38e-142	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
LEFFLKOP_00998	9.72e-182	-	-	-	-	-	-	-	-
LEFFLKOP_00999	5.02e-87	-	-	-	S	-	-	-	SnoaL-like domain
LEFFLKOP_01000	1.62e-161	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
LEFFLKOP_01001	5.24e-278	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_01002	7.57e-210	yybE	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_01003	2.18e-101	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
LEFFLKOP_01004	1.66e-95	yybC	-	-	-	-	-	-	-
LEFFLKOP_01005	1.03e-162	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
LEFFLKOP_01006	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
LEFFLKOP_01007	2.85e-93	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
LEFFLKOP_01008	1.74e-124	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
LEFFLKOP_01009	2.72e-119	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
LEFFLKOP_01010	1.5e-85	-	-	-	S	-	-	-	YjbR
LEFFLKOP_01011	4.99e-136	yyaP	-	-	H	-	-	-	RibD C-terminal domain
LEFFLKOP_01012	0.0	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_01013	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
LEFFLKOP_01014	1.16e-212	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
LEFFLKOP_01015	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
LEFFLKOP_01016	1.33e-129	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
LEFFLKOP_01017	5.93e-89	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEFFLKOP_01018	3.4e-227	ccpB	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_01019	1.4e-185	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
LEFFLKOP_01020	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LEFFLKOP_01021	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LEFFLKOP_01022	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
LEFFLKOP_01023	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LEFFLKOP_01024	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEFFLKOP_01025	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_01026	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
LEFFLKOP_01027	1.3e-144	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
LEFFLKOP_01028	1.32e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
LEFFLKOP_01029	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
LEFFLKOP_01030	2.18e-96	-	-	-	S	-	-	-	Bacterial PH domain
LEFFLKOP_01031	2.58e-192	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LEFFLKOP_01032	1.01e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LEFFLKOP_01033	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LEFFLKOP_01034	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LEFFLKOP_01035	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
LEFFLKOP_01036	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEFFLKOP_01037	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LEFFLKOP_01038	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LEFFLKOP_01039	9.88e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LEFFLKOP_01040	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
LEFFLKOP_01041	1.85e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LEFFLKOP_01042	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
LEFFLKOP_01043	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEFFLKOP_01044	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEFFLKOP_01049	6.37e-185	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
LEFFLKOP_01050	1.58e-36	-	-	-	-	-	-	-	-
LEFFLKOP_01051	3.18e-169	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
LEFFLKOP_01052	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LEFFLKOP_01053	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
LEFFLKOP_01055	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
LEFFLKOP_01056	2.58e-178	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LEFFLKOP_01057	4.19e-218	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
LEFFLKOP_01058	5.86e-190	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LEFFLKOP_01059	9.35e-276	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
LEFFLKOP_01061	4.64e-53	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEFFLKOP_01062	9.35e-101	ygaO	-	-	-	-	-	-	-
LEFFLKOP_01063	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_01065	1.92e-147	yhzB	-	-	S	-	-	-	B3/4 domain
LEFFLKOP_01066	1.7e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LEFFLKOP_01067	1.32e-223	yhbB	-	-	S	-	-	-	Putative amidase domain
LEFFLKOP_01068	6.53e-113	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LEFFLKOP_01069	3.4e-143	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
LEFFLKOP_01070	2.29e-96	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
LEFFLKOP_01071	4.28e-105	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
LEFFLKOP_01072	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
LEFFLKOP_01073	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
LEFFLKOP_01074	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
LEFFLKOP_01075	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
LEFFLKOP_01076	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
LEFFLKOP_01077	9.84e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
LEFFLKOP_01078	3.95e-59	yhcC	-	-	-	-	-	-	-
LEFFLKOP_01079	1.03e-69	-	-	-	-	-	-	-	-
LEFFLKOP_01080	3.37e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_01081	3.38e-158	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_01082	1.85e-212	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_01083	2.32e-210	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LEFFLKOP_01084	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
LEFFLKOP_01085	2.23e-194	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
LEFFLKOP_01086	1.67e-249	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
LEFFLKOP_01087	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEFFLKOP_01088	1.96e-71	yhcM	-	-	-	-	-	-	-
LEFFLKOP_01089	2.69e-111	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEFFLKOP_01090	6.57e-226	yhcP	-	-	-	-	-	-	-
LEFFLKOP_01091	2.29e-144	yhcQ	-	-	M	-	-	-	Spore coat protein
LEFFLKOP_01092	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
LEFFLKOP_01093	1.25e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
LEFFLKOP_01094	6.51e-216	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
LEFFLKOP_01095	2.47e-88	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
LEFFLKOP_01096	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
LEFFLKOP_01097	2.5e-154	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
LEFFLKOP_01098	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LEFFLKOP_01099	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEFFLKOP_01100	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LEFFLKOP_01101	1.63e-195	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
LEFFLKOP_01102	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LEFFLKOP_01103	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LEFFLKOP_01104	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
LEFFLKOP_01105	1.27e-270	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_01106	2.7e-144	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEFFLKOP_01107	5.68e-117	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
LEFFLKOP_01108	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
LEFFLKOP_01109	1.25e-72	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
LEFFLKOP_01110	1.2e-268	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
LEFFLKOP_01111	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
LEFFLKOP_01112	5.04e-305	ygxB	-	-	M	-	-	-	Conserved TM helix
LEFFLKOP_01113	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
LEFFLKOP_01114	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
LEFFLKOP_01115	9.79e-202	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
LEFFLKOP_01116	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_01117	3.56e-259	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
LEFFLKOP_01118	5.51e-206	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEFFLKOP_01119	8.94e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
LEFFLKOP_01120	5e-309	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LEFFLKOP_01121	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEFFLKOP_01122	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEFFLKOP_01123	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
LEFFLKOP_01124	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
LEFFLKOP_01125	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
LEFFLKOP_01126	3.9e-243	yhdN	-	-	C	-	-	-	Aldo keto reductase
LEFFLKOP_01127	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LEFFLKOP_01128	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
LEFFLKOP_01129	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
LEFFLKOP_01130	1.2e-282	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
LEFFLKOP_01131	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
LEFFLKOP_01132	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEFFLKOP_01133	1.67e-86	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEFFLKOP_01134	1.5e-171	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
LEFFLKOP_01135	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
LEFFLKOP_01136	9.73e-239	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
LEFFLKOP_01137	6.62e-177	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LEFFLKOP_01138	3.54e-194	nodB1	-	-	G	-	-	-	deacetylase
LEFFLKOP_01139	2.49e-194	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LEFFLKOP_01140	1.79e-303	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
LEFFLKOP_01141	1.53e-108	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
LEFFLKOP_01142	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
LEFFLKOP_01143	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
LEFFLKOP_01144	2.24e-141	yheG	-	-	GM	-	-	-	NAD(P)H-binding
LEFFLKOP_01145	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
LEFFLKOP_01146	1.32e-48	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
LEFFLKOP_01147	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
LEFFLKOP_01148	3.37e-276	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
LEFFLKOP_01149	1.19e-258	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
LEFFLKOP_01150	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
LEFFLKOP_01151	1.69e-257	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
LEFFLKOP_01152	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
LEFFLKOP_01153	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
LEFFLKOP_01154	1.85e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
LEFFLKOP_01155	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
LEFFLKOP_01157	1.26e-169	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
LEFFLKOP_01158	9.36e-36	-	-	-	S	-	-	-	YhzD-like protein
LEFFLKOP_01159	1.86e-213	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_01160	4.03e-269	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
LEFFLKOP_01161	2.71e-300	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
LEFFLKOP_01162	0.0	yhaN	-	-	L	-	-	-	AAA domain
LEFFLKOP_01163	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
LEFFLKOP_01164	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
LEFFLKOP_01165	5.51e-173	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LEFFLKOP_01166	3.3e-115	yhaK	-	-	S	-	-	-	Putative zincin peptidase
LEFFLKOP_01167	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
LEFFLKOP_01168	2.01e-147	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
LEFFLKOP_01169	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
LEFFLKOP_01170	9.66e-30	-	-	-	-	-	-	-	-
LEFFLKOP_01171	3.66e-103	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
LEFFLKOP_01172	5.91e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LEFFLKOP_01173	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LEFFLKOP_01174	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
LEFFLKOP_01175	1.27e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
LEFFLKOP_01176	2.04e-161	ecsC	-	-	S	-	-	-	EcsC protein family
LEFFLKOP_01177	2.19e-291	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LEFFLKOP_01178	6.63e-313	yhfA	-	-	C	-	-	-	membrane
LEFFLKOP_01179	2.31e-24	-	-	-	C	-	-	-	Rubrerythrin
LEFFLKOP_01180	5.35e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
LEFFLKOP_01181	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
LEFFLKOP_01182	1.06e-258	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LEFFLKOP_01183	3.99e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
LEFFLKOP_01184	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LEFFLKOP_01185	5.79e-132	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_01186	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
LEFFLKOP_01187	4.87e-234	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEFFLKOP_01188	1.61e-178	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
LEFFLKOP_01189	4.44e-252	yhfE	-	-	G	-	-	-	peptidase M42
LEFFLKOP_01190	6.22e-93	-	-	-	S	-	-	-	ASCH
LEFFLKOP_01191	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEFFLKOP_01192	3.43e-182	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LEFFLKOP_01193	3.34e-244	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
LEFFLKOP_01194	2.48e-142	yhfK	-	-	GM	-	-	-	NmrA-like family
LEFFLKOP_01195	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
LEFFLKOP_01196	2.78e-85	yhfM	-	-	-	-	-	-	-
LEFFLKOP_01197	9.64e-308	yhfN	-	-	O	-	-	-	Peptidase M48
LEFFLKOP_01198	1.7e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
LEFFLKOP_01199	2.96e-100	-	-	-	K	-	-	-	acetyltransferase
LEFFLKOP_01200	8.03e-231	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
LEFFLKOP_01201	2.77e-223	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
LEFFLKOP_01202	3.93e-140	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
LEFFLKOP_01203	2.46e-249	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
LEFFLKOP_01204	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
LEFFLKOP_01205	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
LEFFLKOP_01206	1.85e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
LEFFLKOP_01207	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
LEFFLKOP_01208	7.82e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEFFLKOP_01209	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
LEFFLKOP_01210	6.29e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
LEFFLKOP_01211	2.55e-216	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
LEFFLKOP_01212	3.27e-53	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
LEFFLKOP_01213	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEFFLKOP_01214	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
LEFFLKOP_01215	2.57e-78	yhjD	-	-	-	-	-	-	-
LEFFLKOP_01216	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
LEFFLKOP_01217	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
LEFFLKOP_01218	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
LEFFLKOP_01219	3.29e-121	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
LEFFLKOP_01220	2.46e-270	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
LEFFLKOP_01221	7.71e-255	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
LEFFLKOP_01222	6.2e-204	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
LEFFLKOP_01223	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
LEFFLKOP_01224	1.77e-238	yhjM	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_01225	2.5e-259	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
LEFFLKOP_01226	1.04e-271	-	-	-	EGP	-	-	-	Transmembrane secretion effector
LEFFLKOP_01227	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
LEFFLKOP_01228	3.54e-77	yhjQ	-	-	C	-	-	-	COG1145 Ferredoxin
LEFFLKOP_01229	9.3e-102	yhjR	-	-	S	-	-	-	Rubrerythrin
LEFFLKOP_01230	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
LEFFLKOP_01231	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
LEFFLKOP_01232	1.2e-281	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LEFFLKOP_01233	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
LEFFLKOP_01234	7.78e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
LEFFLKOP_01235	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
LEFFLKOP_01236	4.08e-88	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
LEFFLKOP_01237	7.36e-34	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
LEFFLKOP_01238	2.88e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
LEFFLKOP_01239	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
LEFFLKOP_01240	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
LEFFLKOP_01241	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
LEFFLKOP_01242	4.62e-223	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
LEFFLKOP_01243	7.64e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LEFFLKOP_01244	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
LEFFLKOP_01245	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
LEFFLKOP_01246	9.03e-133	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
LEFFLKOP_01247	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
LEFFLKOP_01248	1.49e-114	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
LEFFLKOP_01249	6.54e-191	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
LEFFLKOP_01250	2.91e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
LEFFLKOP_01251	4.04e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_01252	2.5e-233	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
LEFFLKOP_01253	2.02e-246	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
LEFFLKOP_01254	5.98e-121	yisT	-	-	S	-	-	-	DinB family
LEFFLKOP_01255	2.47e-136	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
LEFFLKOP_01256	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEFFLKOP_01257	1.24e-95	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
LEFFLKOP_01258	4.53e-199	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LEFFLKOP_01259	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
LEFFLKOP_01260	1.37e-295	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
LEFFLKOP_01261	9.51e-185	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
LEFFLKOP_01262	1.34e-162	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
LEFFLKOP_01263	4.31e-180	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
LEFFLKOP_01264	6.62e-140	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEFFLKOP_01265	2.14e-283	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
LEFFLKOP_01266	1.01e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_01267	1.4e-200	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
LEFFLKOP_01268	5.09e-92	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
LEFFLKOP_01269	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LEFFLKOP_01270	1.06e-77	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
LEFFLKOP_01271	1.94e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
LEFFLKOP_01272	4.16e-122	-	-	-	-	-	-	-	-
LEFFLKOP_01273	1.42e-218	-	-	-	-	-	-	-	-
LEFFLKOP_01274	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
LEFFLKOP_01275	1.2e-76	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
LEFFLKOP_01276	6.11e-120	-	-	-	-	-	-	-	-
LEFFLKOP_01277	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
LEFFLKOP_01278	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
LEFFLKOP_01279	9.13e-202	yitS	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_01280	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
LEFFLKOP_01281	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
LEFFLKOP_01282	4.11e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
LEFFLKOP_01283	1.92e-08	-	-	-	-	-	-	-	-
LEFFLKOP_01284	1.07e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
LEFFLKOP_01285	5.05e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
LEFFLKOP_01286	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
LEFFLKOP_01287	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
LEFFLKOP_01288	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
LEFFLKOP_01289	3.24e-114	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
LEFFLKOP_01290	7.41e-255	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LEFFLKOP_01291	7.4e-295	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LEFFLKOP_01292	5.4e-177	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
LEFFLKOP_01293	1.69e-278	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
LEFFLKOP_01294	2.33e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
LEFFLKOP_01295	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
LEFFLKOP_01296	3.66e-226	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LEFFLKOP_01297	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
LEFFLKOP_01298	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
LEFFLKOP_01299	2.42e-182	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
LEFFLKOP_01300	5.41e-134	yjaV	-	-	-	-	-	-	-
LEFFLKOP_01301	6.4e-235	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
LEFFLKOP_01302	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
LEFFLKOP_01303	2.67e-38	yjzB	-	-	-	-	-	-	-
LEFFLKOP_01304	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEFFLKOP_01305	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEFFLKOP_01306	9.48e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
LEFFLKOP_01307	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
LEFFLKOP_01308	2.07e-237	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
LEFFLKOP_01309	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
LEFFLKOP_01310	1.04e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEFFLKOP_01311	1.03e-208	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEFFLKOP_01312	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
LEFFLKOP_01313	7.18e-234	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
LEFFLKOP_01314	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
LEFFLKOP_01315	1.03e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEFFLKOP_01316	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEFFLKOP_01317	1.37e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
LEFFLKOP_01318	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
LEFFLKOP_01319	3.98e-248	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
LEFFLKOP_01320	8.88e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEFFLKOP_01321	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LEFFLKOP_01322	7.1e-144	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
LEFFLKOP_01323	5.66e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LEFFLKOP_01324	2.53e-281	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
LEFFLKOP_01325	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
LEFFLKOP_01326	2.68e-28	-	-	-	-	-	-	-	-
LEFFLKOP_01327	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
LEFFLKOP_01328	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
LEFFLKOP_01329	2.19e-123	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LEFFLKOP_01330	7.02e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_01331	4.41e-80	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
LEFFLKOP_01332	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
LEFFLKOP_01333	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEFFLKOP_01334	9.4e-206	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
LEFFLKOP_01335	4.68e-180	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LEFFLKOP_01336	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LEFFLKOP_01337	5.7e-177	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LEFFLKOP_01338	4.01e-139	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
LEFFLKOP_01339	1.09e-275	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
LEFFLKOP_01340	2.18e-41	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
LEFFLKOP_01341	2.76e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LEFFLKOP_01342	2.94e-236	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LEFFLKOP_01343	4.85e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
LEFFLKOP_01344	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
LEFFLKOP_01345	5.16e-104	yjbX	-	-	S	-	-	-	Spore coat protein
LEFFLKOP_01346	3.92e-107	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
LEFFLKOP_01347	6.3e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
LEFFLKOP_01348	1.23e-95	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
LEFFLKOP_01349	9.3e-32	cotW	-	-	-	ko:K06341	-	ko00000	-
LEFFLKOP_01350	2.34e-66	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
LEFFLKOP_01351	1.23e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
LEFFLKOP_01354	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
LEFFLKOP_01355	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
LEFFLKOP_01356	6.31e-51	-	-	-	-	-	-	-	-
LEFFLKOP_01357	1.1e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEFFLKOP_01358	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
LEFFLKOP_01359	1.91e-177	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
LEFFLKOP_01360	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
LEFFLKOP_01361	7.47e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
LEFFLKOP_01362	7.14e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
LEFFLKOP_01363	1.05e-273	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
LEFFLKOP_01366	3.8e-50	-	-	-	-	-	-	-	-
LEFFLKOP_01368	2.35e-295	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
LEFFLKOP_01371	1.42e-09	-	-	-	S	-	-	-	YolD-like protein
LEFFLKOP_01372	1.92e-47	-	-	-	-	-	-	-	-
LEFFLKOP_01373	3.94e-26	-	-	-	-	-	-	-	-
LEFFLKOP_01374	2.49e-07	-	-	-	-	-	-	-	-
LEFFLKOP_01375	1.27e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
LEFFLKOP_01376	2.81e-180	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
LEFFLKOP_01377	0.000388	-	-	-	-	-	-	-	-
LEFFLKOP_01378	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
LEFFLKOP_01379	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFFLKOP_01380	5.95e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
LEFFLKOP_01381	5.1e-73	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
LEFFLKOP_01382	5.12e-117	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
LEFFLKOP_01384	1.12e-101	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LEFFLKOP_01385	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
LEFFLKOP_01386	2.31e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
LEFFLKOP_01387	2.16e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LEFFLKOP_01389	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
LEFFLKOP_01390	3.54e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
LEFFLKOP_01391	1.13e-29	yjfB	-	-	S	-	-	-	Putative motility protein
LEFFLKOP_01392	7.02e-214	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
LEFFLKOP_01393	5.62e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
LEFFLKOP_01394	4.96e-133	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
LEFFLKOP_01395	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
LEFFLKOP_01396	2.27e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
LEFFLKOP_01398	3.7e-147	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
LEFFLKOP_01400	1.25e-281	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
LEFFLKOP_01401	4.84e-277	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LEFFLKOP_01402	1.11e-41	-	-	-	-	-	-	-	-
LEFFLKOP_01403	2.79e-185	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
LEFFLKOP_01404	1.82e-155	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
LEFFLKOP_01405	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
LEFFLKOP_01406	7.35e-224	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
LEFFLKOP_01407	4.08e-117	yjlB	-	-	S	-	-	-	Cupin domain
LEFFLKOP_01408	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
LEFFLKOP_01409	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
LEFFLKOP_01410	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
LEFFLKOP_01411	6.16e-314	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
LEFFLKOP_01412	4.2e-241	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
LEFFLKOP_01413	4.91e-241	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
LEFFLKOP_01414	1.6e-272	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
LEFFLKOP_01415	1.34e-196	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
LEFFLKOP_01416	5.34e-287	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
LEFFLKOP_01417	8.11e-237	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
LEFFLKOP_01418	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
LEFFLKOP_01419	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
LEFFLKOP_01420	1.59e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
LEFFLKOP_01421	4.87e-106	yjoA	-	-	S	-	-	-	DinB family
LEFFLKOP_01422	6.08e-314	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
LEFFLKOP_01423	1.6e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
LEFFLKOP_01425	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
LEFFLKOP_01426	1.37e-220	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
LEFFLKOP_01427	3.31e-81	yjqA	-	-	S	-	-	-	Bacterial PH domain
LEFFLKOP_01428	1.47e-143	yjqB	-	-	S	-	-	-	Pfam:DUF867
LEFFLKOP_01429	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
LEFFLKOP_01430	1.53e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
LEFFLKOP_01431	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
LEFFLKOP_01433	3.73e-203	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
LEFFLKOP_01434	7.48e-153	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
LEFFLKOP_01438	5.95e-112	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LEFFLKOP_01439	1.18e-179	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
LEFFLKOP_01440	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
LEFFLKOP_01441	0.0	yqbA	-	-	S	-	-	-	portal protein
LEFFLKOP_01442	9.88e-177	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
LEFFLKOP_01443	6.48e-216	xkdG	-	-	S	-	-	-	Phage capsid family
LEFFLKOP_01444	3.85e-81	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
LEFFLKOP_01445	1.05e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
LEFFLKOP_01446	5.84e-115	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
LEFFLKOP_01447	2.36e-100	xkdJ	-	-	-	-	-	-	-
LEFFLKOP_01448	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
LEFFLKOP_01449	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
LEFFLKOP_01450	3.21e-99	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
LEFFLKOP_01451	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
LEFFLKOP_01452	1.48e-152	xkdP	-	-	S	-	-	-	Lysin motif
LEFFLKOP_01453	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
LEFFLKOP_01454	1.76e-52	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
LEFFLKOP_01455	7.71e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
LEFFLKOP_01456	1.79e-243	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LEFFLKOP_01457	3.23e-134	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
LEFFLKOP_01458	6.29e-56	-	-	-	-	-	-	-	-
LEFFLKOP_01459	2.88e-221	-	-	-	-	-	-	-	-
LEFFLKOP_01460	3.67e-59	xkdW	-	-	S	-	-	-	XkdW protein
LEFFLKOP_01461	6.35e-31	xkdX	-	-	-	-	-	-	-
LEFFLKOP_01462	2.21e-193	xepA	-	-	-	-	-	-	-
LEFFLKOP_01463	2.21e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
LEFFLKOP_01464	1.15e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
LEFFLKOP_01465	5.3e-208	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
LEFFLKOP_01467	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
LEFFLKOP_01468	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
LEFFLKOP_01469	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
LEFFLKOP_01470	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
LEFFLKOP_01471	2.57e-309	steT	-	-	E	ko:K03294	-	ko00000	amino acid
LEFFLKOP_01472	9.82e-234	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
LEFFLKOP_01473	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LEFFLKOP_01474	2.21e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
LEFFLKOP_01476	2.41e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEFFLKOP_01477	1.16e-178	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
LEFFLKOP_01478	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
LEFFLKOP_01479	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEFFLKOP_01480	9.02e-226	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEFFLKOP_01481	1.35e-236	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
LEFFLKOP_01482	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
LEFFLKOP_01484	2.46e-227	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
LEFFLKOP_01485	2.4e-257	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
LEFFLKOP_01486	3.08e-211	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LEFFLKOP_01487	8.44e-237	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
LEFFLKOP_01488	3.84e-259	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
LEFFLKOP_01489	1.78e-205	ykgA	-	-	E	-	-	-	Amidinotransferase
LEFFLKOP_01490	2.21e-119	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
LEFFLKOP_01491	8.85e-286	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LEFFLKOP_01492	1.13e-166	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
LEFFLKOP_01493	1.24e-125	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
LEFFLKOP_01494	1.2e-126	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LEFFLKOP_01495	1.27e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
LEFFLKOP_01496	1.36e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
LEFFLKOP_01497	9.63e-217	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LEFFLKOP_01498	3.68e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEFFLKOP_01499	5.59e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LEFFLKOP_01501	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
LEFFLKOP_01502	2.02e-97	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
LEFFLKOP_01503	8.15e-94	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
LEFFLKOP_01504	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
LEFFLKOP_01505	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LEFFLKOP_01506	4.27e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
LEFFLKOP_01507	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEFFLKOP_01508	3.65e-173	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
LEFFLKOP_01509	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_01510	1.39e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
LEFFLKOP_01511	2.34e-140	ykoF	-	-	S	-	-	-	YKOF-related Family
LEFFLKOP_01512	3.03e-159	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEFFLKOP_01513	3.13e-309	ykoH	-	-	T	-	-	-	Histidine kinase
LEFFLKOP_01514	3.74e-143	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
LEFFLKOP_01515	1.3e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
LEFFLKOP_01516	1.45e-08	-	-	-	-	-	-	-	-
LEFFLKOP_01518	1.99e-299	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
LEFFLKOP_01519	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
LEFFLKOP_01520	1.63e-25	-	-	-	-	-	-	-	-
LEFFLKOP_01521	3.04e-36	ykoL	-	-	-	-	-	-	-
LEFFLKOP_01522	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
LEFFLKOP_01523	1.19e-281	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
LEFFLKOP_01524	2.48e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
LEFFLKOP_01525	4.35e-198	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
LEFFLKOP_01526	0.0	ykoS	-	-	-	-	-	-	-
LEFFLKOP_01527	5.72e-239	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
LEFFLKOP_01528	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
LEFFLKOP_01529	7.55e-206	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LEFFLKOP_01530	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
LEFFLKOP_01531	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
LEFFLKOP_01532	1.33e-226	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LEFFLKOP_01533	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEFFLKOP_01534	1.63e-212	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
LEFFLKOP_01535	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
LEFFLKOP_01536	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
LEFFLKOP_01537	9.33e-198	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
LEFFLKOP_01538	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
LEFFLKOP_01540	1.77e-28	ykzE	-	-	-	-	-	-	-
LEFFLKOP_01541	3.34e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
LEFFLKOP_01542	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_01543	1.53e-112	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEFFLKOP_01545	1.33e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LEFFLKOP_01546	2.47e-293	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LEFFLKOP_01547	1.99e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LEFFLKOP_01548	1.13e-294	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
LEFFLKOP_01549	2.29e-293	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LEFFLKOP_01550	1.77e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LEFFLKOP_01551	2.61e-146	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LEFFLKOP_01552	8.7e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LEFFLKOP_01553	3.6e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
LEFFLKOP_01555	1.18e-94	eag	-	-	-	-	-	-	-
LEFFLKOP_01556	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
LEFFLKOP_01557	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
LEFFLKOP_01558	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
LEFFLKOP_01559	1.65e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
LEFFLKOP_01560	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
LEFFLKOP_01561	6.76e-227	ykvI	-	-	S	-	-	-	membrane
LEFFLKOP_01562	1.11e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LEFFLKOP_01563	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
LEFFLKOP_01564	1.45e-178	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LEFFLKOP_01565	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LEFFLKOP_01566	3.53e-81	ykvN	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_01567	3.81e-172	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
LEFFLKOP_01568	8.62e-272	-	-	-	M	-	-	-	Glycosyl transferases group 1
LEFFLKOP_01569	2.87e-43	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
LEFFLKOP_01570	3.53e-204	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
LEFFLKOP_01571	2.2e-61	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
LEFFLKOP_01572	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_01573	2.6e-39	-	-	-	-	-	-	-	-
LEFFLKOP_01574	9.09e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
LEFFLKOP_01575	2.63e-301	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEFFLKOP_01576	1.12e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
LEFFLKOP_01577	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
LEFFLKOP_01578	3.99e-09	-	-	-	-	-	-	-	-
LEFFLKOP_01579	4.54e-263	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
LEFFLKOP_01580	6.34e-228	ykvZ	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_01582	6.87e-168	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
LEFFLKOP_01583	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFFLKOP_01584	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
LEFFLKOP_01585	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LEFFLKOP_01586	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_01587	2.13e-257	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
LEFFLKOP_01588	1.06e-167	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEFFLKOP_01589	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
LEFFLKOP_01590	4.02e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LEFFLKOP_01591	2.97e-169	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
LEFFLKOP_01592	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
LEFFLKOP_01593	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_01594	3.44e-282	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
LEFFLKOP_01595	1.05e-22	-	-	-	-	-	-	-	-
LEFFLKOP_01596	2.02e-215	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
LEFFLKOP_01597	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
LEFFLKOP_01598	2.97e-304	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_01599	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_01600	2.45e-210	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
LEFFLKOP_01601	2.91e-179	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEFFLKOP_01602	2.05e-297	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
LEFFLKOP_01603	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_01604	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
LEFFLKOP_01605	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
LEFFLKOP_01606	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
LEFFLKOP_01607	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_01608	8.34e-109	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
LEFFLKOP_01609	7.7e-226	ykuO	-	-	-	-	-	-	-
LEFFLKOP_01610	6.2e-103	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
LEFFLKOP_01611	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LEFFLKOP_01612	7.66e-274	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LEFFLKOP_01613	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
LEFFLKOP_01614	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
LEFFLKOP_01615	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
LEFFLKOP_01616	1.47e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
LEFFLKOP_01617	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
LEFFLKOP_01618	2.43e-200	yknT	-	-	-	ko:K06437	-	ko00000	-
LEFFLKOP_01619	3.75e-141	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LEFFLKOP_01620	1.26e-243	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LEFFLKOP_01621	2.38e-310	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
LEFFLKOP_01622	4.89e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
LEFFLKOP_01623	3.83e-109	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
LEFFLKOP_01624	2.82e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LEFFLKOP_01625	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
LEFFLKOP_01626	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
LEFFLKOP_01627	5.34e-150	yknW	-	-	S	-	-	-	Yip1 domain
LEFFLKOP_01628	8.16e-234	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEFFLKOP_01629	1.44e-158	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_01630	1.92e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
LEFFLKOP_01631	7.41e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_01632	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
LEFFLKOP_01633	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LEFFLKOP_01634	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
LEFFLKOP_01635	5.43e-52	ykoA	-	-	-	-	-	-	-
LEFFLKOP_01636	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LEFFLKOP_01637	2.86e-215	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEFFLKOP_01638	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
LEFFLKOP_01639	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
LEFFLKOP_01640	3.57e-233	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
LEFFLKOP_01641	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
LEFFLKOP_01642	4.59e-307	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
LEFFLKOP_01643	3.42e-198	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
LEFFLKOP_01644	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
LEFFLKOP_01645	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LEFFLKOP_01646	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEFFLKOP_01647	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
LEFFLKOP_01648	4.79e-186	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
LEFFLKOP_01649	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEFFLKOP_01650	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
LEFFLKOP_01651	2.59e-139	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
LEFFLKOP_01652	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEFFLKOP_01653	1.75e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEFFLKOP_01654	2.08e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEFFLKOP_01655	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEFFLKOP_01656	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
LEFFLKOP_01657	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
LEFFLKOP_01658	1.34e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
LEFFLKOP_01659	1.45e-149	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
LEFFLKOP_01660	4.48e-35	ykzI	-	-	-	-	-	-	-
LEFFLKOP_01661	9.48e-195	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
LEFFLKOP_01662	2.98e-100	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
LEFFLKOP_01663	8.26e-220	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LEFFLKOP_01664	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
LEFFLKOP_01665	0.0	ylaA	-	-	-	-	-	-	-
LEFFLKOP_01666	1.44e-56	ylaB	-	-	-	-	-	-	-
LEFFLKOP_01667	3.56e-115	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
LEFFLKOP_01669	1.74e-57	ylaE	-	-	-	-	-	-	-
LEFFLKOP_01670	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
LEFFLKOP_01671	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
LEFFLKOP_01672	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
LEFFLKOP_01673	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_01674	2.97e-127	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEFFLKOP_01675	3.76e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
LEFFLKOP_01676	1.09e-110	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LEFFLKOP_01677	3.49e-219	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
LEFFLKOP_01678	5.71e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
LEFFLKOP_01679	2.87e-270	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
LEFFLKOP_01680	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LEFFLKOP_01681	1.65e-211	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LEFFLKOP_01682	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LEFFLKOP_01683	2.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LEFFLKOP_01684	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LEFFLKOP_01685	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LEFFLKOP_01686	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LEFFLKOP_01687	1.48e-214	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
LEFFLKOP_01688	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
LEFFLKOP_01689	1.08e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
LEFFLKOP_01690	1.53e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
LEFFLKOP_01691	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
LEFFLKOP_01692	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
LEFFLKOP_01693	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
LEFFLKOP_01694	5.1e-51	ylbG	-	-	S	-	-	-	UPF0298 protein
LEFFLKOP_01695	3.51e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
LEFFLKOP_01696	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LEFFLKOP_01697	3.87e-282	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
LEFFLKOP_01698	3.64e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
LEFFLKOP_01699	1.58e-238	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
LEFFLKOP_01700	5.94e-301	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
LEFFLKOP_01702	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
LEFFLKOP_01703	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
LEFFLKOP_01704	4.72e-107	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LEFFLKOP_01705	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
LEFFLKOP_01706	1.86e-213	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEFFLKOP_01707	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LEFFLKOP_01708	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
LEFFLKOP_01709	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LEFFLKOP_01710	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
LEFFLKOP_01711	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
LEFFLKOP_01712	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
LEFFLKOP_01713	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEFFLKOP_01714	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEFFLKOP_01715	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LEFFLKOP_01716	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
LEFFLKOP_01717	4.66e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LEFFLKOP_01718	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
LEFFLKOP_01719	1.18e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LEFFLKOP_01720	4.5e-142	ylxW	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_01721	1.03e-123	ylxX	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_01722	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
LEFFLKOP_01723	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LEFFLKOP_01724	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LEFFLKOP_01725	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
LEFFLKOP_01727	1.48e-220	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LEFFLKOP_01728	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEFFLKOP_01729	1.14e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEFFLKOP_01730	1.83e-187	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LEFFLKOP_01731	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
LEFFLKOP_01732	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
LEFFLKOP_01733	3.58e-201	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
LEFFLKOP_01734	9.03e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LEFFLKOP_01735	4.47e-87	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LEFFLKOP_01736	1.74e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
LEFFLKOP_01737	1.23e-177	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
LEFFLKOP_01738	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
LEFFLKOP_01739	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LEFFLKOP_01740	3.74e-82	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
LEFFLKOP_01741	2.71e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LEFFLKOP_01742	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
LEFFLKOP_01743	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LEFFLKOP_01744	1.3e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
LEFFLKOP_01745	7.29e-214	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
LEFFLKOP_01746	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LEFFLKOP_01747	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
LEFFLKOP_01748	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
LEFFLKOP_01749	1.57e-184	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LEFFLKOP_01750	1.22e-220	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LEFFLKOP_01751	6.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LEFFLKOP_01752	1.27e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LEFFLKOP_01754	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
LEFFLKOP_01755	6.01e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
LEFFLKOP_01756	2.15e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
LEFFLKOP_01757	3.76e-140	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
LEFFLKOP_01758	5.9e-185	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
LEFFLKOP_01759	1.45e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
LEFFLKOP_01760	1.08e-106	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
LEFFLKOP_01761	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
LEFFLKOP_01762	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
LEFFLKOP_01763	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
LEFFLKOP_01764	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
LEFFLKOP_01765	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
LEFFLKOP_01766	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LEFFLKOP_01767	7.28e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LEFFLKOP_01768	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEFFLKOP_01769	8.3e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEFFLKOP_01770	1.28e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LEFFLKOP_01771	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEFFLKOP_01772	5.3e-264	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LEFFLKOP_01773	3.54e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
LEFFLKOP_01774	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
LEFFLKOP_01775	3.92e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LEFFLKOP_01776	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
LEFFLKOP_01777	8.13e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
LEFFLKOP_01778	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
LEFFLKOP_01779	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_01780	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
LEFFLKOP_01781	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
LEFFLKOP_01782	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
LEFFLKOP_01783	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LEFFLKOP_01784	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LEFFLKOP_01785	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LEFFLKOP_01786	1.79e-216	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
LEFFLKOP_01787	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
LEFFLKOP_01788	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEFFLKOP_01789	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LEFFLKOP_01790	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
LEFFLKOP_01791	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LEFFLKOP_01792	1.67e-114	-	-	-	-	-	-	-	-
LEFFLKOP_01793	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LEFFLKOP_01794	9.7e-309	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LEFFLKOP_01795	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
LEFFLKOP_01796	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
LEFFLKOP_01797	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
LEFFLKOP_01798	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LEFFLKOP_01799	2.41e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
LEFFLKOP_01800	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LEFFLKOP_01801	4.89e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LEFFLKOP_01802	2.89e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEFFLKOP_01803	0.0	ylqG	-	-	-	-	-	-	-
LEFFLKOP_01804	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
LEFFLKOP_01805	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LEFFLKOP_01806	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LEFFLKOP_01807	2.66e-217	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
LEFFLKOP_01808	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEFFLKOP_01809	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LEFFLKOP_01810	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
LEFFLKOP_01811	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LEFFLKOP_01812	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LEFFLKOP_01813	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LEFFLKOP_01814	3.27e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LEFFLKOP_01815	7.54e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
LEFFLKOP_01816	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
LEFFLKOP_01817	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
LEFFLKOP_01818	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LEFFLKOP_01819	1.92e-144	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
LEFFLKOP_01820	1.22e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LEFFLKOP_01821	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
LEFFLKOP_01822	5.08e-84	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
LEFFLKOP_01823	1.28e-311	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
LEFFLKOP_01824	2.81e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
LEFFLKOP_01825	1.09e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
LEFFLKOP_01826	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
LEFFLKOP_01827	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LEFFLKOP_01828	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LEFFLKOP_01829	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
LEFFLKOP_01830	7.87e-137	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
LEFFLKOP_01831	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
LEFFLKOP_01832	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
LEFFLKOP_01833	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
LEFFLKOP_01834	2.74e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LEFFLKOP_01835	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LEFFLKOP_01836	5.65e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
LEFFLKOP_01837	1.09e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
LEFFLKOP_01838	2.58e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LEFFLKOP_01839	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
LEFFLKOP_01840	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
LEFFLKOP_01841	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LEFFLKOP_01842	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LEFFLKOP_01843	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEFFLKOP_01844	6.62e-99	ylxL	-	-	-	-	-	-	-
LEFFLKOP_01845	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
LEFFLKOP_01846	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LEFFLKOP_01847	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
LEFFLKOP_01848	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LEFFLKOP_01849	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEFFLKOP_01850	5.77e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
LEFFLKOP_01851	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LEFFLKOP_01852	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
LEFFLKOP_01853	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LEFFLKOP_01854	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEFFLKOP_01855	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
LEFFLKOP_01856	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
LEFFLKOP_01857	5.78e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
LEFFLKOP_01858	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
LEFFLKOP_01859	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LEFFLKOP_01860	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
LEFFLKOP_01861	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LEFFLKOP_01862	6.04e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LEFFLKOP_01863	1.34e-231	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
LEFFLKOP_01864	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LEFFLKOP_01865	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LEFFLKOP_01866	2.92e-232	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
LEFFLKOP_01867	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
LEFFLKOP_01868	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
LEFFLKOP_01869	5.3e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
LEFFLKOP_01870	8.17e-141	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LEFFLKOP_01871	4.77e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEFFLKOP_01872	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
LEFFLKOP_01873	9.08e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEFFLKOP_01874	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEFFLKOP_01875	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
LEFFLKOP_01876	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
LEFFLKOP_01877	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
LEFFLKOP_01878	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_01879	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_01880	1.35e-298	albE	-	-	S	-	-	-	Peptidase M16
LEFFLKOP_01881	6.8e-309	ymfH	-	-	S	-	-	-	zinc protease
LEFFLKOP_01882	1.49e-166	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LEFFLKOP_01883	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
LEFFLKOP_01884	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
LEFFLKOP_01885	3.05e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
LEFFLKOP_01886	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEFFLKOP_01887	4.33e-299	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
LEFFLKOP_01888	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LEFFLKOP_01889	2.82e-280	pbpX	-	-	V	-	-	-	Beta-lactamase
LEFFLKOP_01890	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
LEFFLKOP_01891	5.08e-194	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
LEFFLKOP_01892	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
LEFFLKOP_01893	7.12e-254	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LEFFLKOP_01894	2.4e-277	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LEFFLKOP_01895	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LEFFLKOP_01896	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
LEFFLKOP_01897	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
LEFFLKOP_01898	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LEFFLKOP_01899	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LEFFLKOP_01900	2.93e-92	-	-	-	S	-	-	-	Regulatory protein YrvL
LEFFLKOP_01902	1.13e-126	ymcC	-	-	S	-	-	-	Membrane
LEFFLKOP_01903	3.43e-140	pksA	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_01904	9.47e-166	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
LEFFLKOP_01905	2.17e-207	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
LEFFLKOP_01907	3.17e-234	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
LEFFLKOP_01908	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
LEFFLKOP_01909	5.46e-51	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
LEFFLKOP_01910	4.36e-303	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEFFLKOP_01911	9.7e-314	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
LEFFLKOP_01912	2.04e-183	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
LEFFLKOP_01913	4.29e-174	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
LEFFLKOP_01914	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
LEFFLKOP_01915	0.0	-	-	-	Q	ko:K13612	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
LEFFLKOP_01916	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
LEFFLKOP_01917	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
LEFFLKOP_01918	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
LEFFLKOP_01919	1.13e-293	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
LEFFLKOP_01920	5.65e-81	ymzB	-	-	-	-	-	-	-
LEFFLKOP_01921	1.04e-204	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
LEFFLKOP_01922	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
LEFFLKOP_01924	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
LEFFLKOP_01925	1.03e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
LEFFLKOP_01926	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
LEFFLKOP_01927	1.21e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
LEFFLKOP_01929	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
LEFFLKOP_01930	9.69e-224	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LEFFLKOP_01931	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LEFFLKOP_01932	2.69e-30	-	-	-	-	-	-	-	-
LEFFLKOP_01933	1.2e-30	ymzA	-	-	-	-	-	-	-
LEFFLKOP_01934	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
LEFFLKOP_01935	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEFFLKOP_01936	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEFFLKOP_01937	3.05e-139	-	-	-	-	-	-	-	-
LEFFLKOP_01938	2.13e-145	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
LEFFLKOP_01939	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
LEFFLKOP_01940	7.4e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LEFFLKOP_01941	1.67e-310	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LEFFLKOP_01942	9.94e-90	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
LEFFLKOP_01943	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
LEFFLKOP_01944	4.61e-47	-	-	-	L	-	-	-	Arm DNA-binding domain
LEFFLKOP_01945	9.44e-127	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	replicative DNA helicase
LEFFLKOP_01946	3.5e-30	-	-	-	-	-	-	-	-
LEFFLKOP_01949	4.9e-66	-	-	-	M	-	-	-	ArpU family transcriptional regulator
LEFFLKOP_01950	1.82e-31	-	-	-	S	-	-	-	FRG
LEFFLKOP_01951	1.4e-86	-	-	-	S	-	-	-	regulation of transcription, DNA-dependent
LEFFLKOP_01952	4.25e-25	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
LEFFLKOP_01957	1.89e-63	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
LEFFLKOP_01958	6.85e-103	-	-	-	L	-	-	-	phage terminase small subunit
LEFFLKOP_01959	1.04e-42	-	-	-	S	-	-	-	Terminase
LEFFLKOP_01962	4.18e-14	-	-	-	-	-	-	-	-
LEFFLKOP_01965	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
LEFFLKOP_01966	9.38e-171	-	-	-	-	-	-	-	-
LEFFLKOP_01967	3e-169	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
LEFFLKOP_01968	1.29e-23	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
LEFFLKOP_01969	9.36e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
LEFFLKOP_01970	4.44e-172	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
LEFFLKOP_01971	6.41e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
LEFFLKOP_01973	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
LEFFLKOP_01974	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LEFFLKOP_01975	1.4e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEFFLKOP_01976	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
LEFFLKOP_01977	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LEFFLKOP_01978	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
LEFFLKOP_01979	6.61e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LEFFLKOP_01980	9.8e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
LEFFLKOP_01981	4.46e-188	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEFFLKOP_01982	1.83e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
LEFFLKOP_01983	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
LEFFLKOP_01984	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
LEFFLKOP_01985	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
LEFFLKOP_01986	2.01e-244	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
LEFFLKOP_01987	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
LEFFLKOP_01988	4.16e-259	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LEFFLKOP_01989	9.53e-284	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
LEFFLKOP_01990	6.28e-73	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
LEFFLKOP_01991	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEFFLKOP_01992	4.3e-278	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
LEFFLKOP_01993	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LEFFLKOP_01994	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LEFFLKOP_01995	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
LEFFLKOP_01996	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LEFFLKOP_01997	5.63e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
LEFFLKOP_01998	1.01e-180	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LEFFLKOP_01999	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
LEFFLKOP_02000	3.45e-202	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
LEFFLKOP_02001	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
LEFFLKOP_02002	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
LEFFLKOP_02003	1.32e-290	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
LEFFLKOP_02004	8.78e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
LEFFLKOP_02005	3.13e-79	yqfB	-	-	-	-	-	-	-
LEFFLKOP_02006	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
LEFFLKOP_02007	1.04e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
LEFFLKOP_02008	2.47e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
LEFFLKOP_02010	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
LEFFLKOP_02011	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LEFFLKOP_02012	1.42e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
LEFFLKOP_02013	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LEFFLKOP_02014	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LEFFLKOP_02015	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
LEFFLKOP_02016	5.26e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
LEFFLKOP_02017	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
LEFFLKOP_02018	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
LEFFLKOP_02019	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
LEFFLKOP_02020	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LEFFLKOP_02021	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
LEFFLKOP_02022	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LEFFLKOP_02023	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LEFFLKOP_02024	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
LEFFLKOP_02025	2.41e-150	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
LEFFLKOP_02026	9.26e-270	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LEFFLKOP_02027	8.66e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LEFFLKOP_02028	4.45e-45	yqfQ	-	-	S	-	-	-	YqfQ-like protein
LEFFLKOP_02029	5.42e-311	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LEFFLKOP_02030	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LEFFLKOP_02031	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
LEFFLKOP_02032	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
LEFFLKOP_02033	2.47e-106	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
LEFFLKOP_02034	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
LEFFLKOP_02035	2.04e-81	yqfX	-	-	S	-	-	-	membrane
LEFFLKOP_02036	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LEFFLKOP_02037	4.72e-62	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
LEFFLKOP_02038	1.58e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
LEFFLKOP_02039	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
LEFFLKOP_02040	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
LEFFLKOP_02041	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
LEFFLKOP_02042	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
LEFFLKOP_02043	2.61e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
LEFFLKOP_02044	7.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
LEFFLKOP_02045	8.71e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
LEFFLKOP_02046	1.62e-188	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEFFLKOP_02047	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEFFLKOP_02048	1.09e-93	yqzC	-	-	S	-	-	-	YceG-like family
LEFFLKOP_02049	2.81e-67	yqzD	-	-	-	-	-	-	-
LEFFLKOP_02051	2.81e-257	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
LEFFLKOP_02052	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
LEFFLKOP_02053	3.8e-135	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LEFFLKOP_02054	3.38e-14	yqgO	-	-	-	-	-	-	-
LEFFLKOP_02055	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
LEFFLKOP_02056	2.19e-44	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
LEFFLKOP_02057	2.81e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
LEFFLKOP_02058	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
LEFFLKOP_02059	3.04e-283	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
LEFFLKOP_02060	6.6e-257	yqgU	-	-	-	-	-	-	-
LEFFLKOP_02061	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
LEFFLKOP_02062	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
LEFFLKOP_02063	3.2e-157	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
LEFFLKOP_02064	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
LEFFLKOP_02065	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
LEFFLKOP_02067	7.14e-192	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEFFLKOP_02068	2.86e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
LEFFLKOP_02069	1.51e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
LEFFLKOP_02070	3.8e-06	-	-	-	S	-	-	-	Domain in cystathionine beta-synthase and other proteins.
LEFFLKOP_02072	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LEFFLKOP_02073	2.14e-219	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
LEFFLKOP_02074	3.09e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
LEFFLKOP_02075	1.05e-88	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
LEFFLKOP_02076	3.45e-76	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
LEFFLKOP_02077	2.77e-44	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
LEFFLKOP_02078	3.24e-58	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
LEFFLKOP_02079	3.33e-35	yqzE	-	-	S	-	-	-	YqzE-like protein
LEFFLKOP_02080	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
LEFFLKOP_02081	2.29e-155	yqxM	-	-	-	ko:K19433	-	ko00000	-
LEFFLKOP_02082	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
LEFFLKOP_02083	1.28e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
LEFFLKOP_02084	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
LEFFLKOP_02085	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
LEFFLKOP_02086	9.14e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
LEFFLKOP_02087	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
LEFFLKOP_02088	5.49e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
LEFFLKOP_02089	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LEFFLKOP_02090	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LEFFLKOP_02091	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
LEFFLKOP_02092	9.17e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LEFFLKOP_02093	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LEFFLKOP_02094	3.33e-208	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
LEFFLKOP_02095	5.18e-81	yqhP	-	-	-	-	-	-	-
LEFFLKOP_02096	6.02e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
LEFFLKOP_02097	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
LEFFLKOP_02098	1.17e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
LEFFLKOP_02099	2.99e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
LEFFLKOP_02100	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEFFLKOP_02101	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
LEFFLKOP_02102	3.35e-216	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
LEFFLKOP_02103	5.69e-111	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
LEFFLKOP_02104	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
LEFFLKOP_02105	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
LEFFLKOP_02106	1.8e-255	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
LEFFLKOP_02107	2.58e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
LEFFLKOP_02108	2.43e-145	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
LEFFLKOP_02109	4.04e-134	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
LEFFLKOP_02110	1.31e-92	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LEFFLKOP_02111	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LEFFLKOP_02112	1.65e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_02113	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEFFLKOP_02114	1.07e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LEFFLKOP_02115	2.05e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEFFLKOP_02116	3.81e-50	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEFFLKOP_02117	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
LEFFLKOP_02118	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEFFLKOP_02119	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
LEFFLKOP_02120	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
LEFFLKOP_02121	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
LEFFLKOP_02122	1.26e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
LEFFLKOP_02123	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LEFFLKOP_02125	3.43e-274	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LEFFLKOP_02126	4.74e-37	-	-	-	-	-	-	-	-
LEFFLKOP_02127	2.7e-137	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
LEFFLKOP_02128	7.42e-172	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
LEFFLKOP_02129	5.7e-281	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
LEFFLKOP_02130	2.41e-199	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
LEFFLKOP_02131	1.93e-265	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
LEFFLKOP_02132	1.12e-265	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
LEFFLKOP_02133	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
LEFFLKOP_02134	3.58e-208	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LEFFLKOP_02135	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
LEFFLKOP_02136	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
LEFFLKOP_02137	1.74e-198	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
LEFFLKOP_02138	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
LEFFLKOP_02139	3.96e-254	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
LEFFLKOP_02140	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEFFLKOP_02141	1.92e-238	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEFFLKOP_02142	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEFFLKOP_02143	2.18e-287	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEFFLKOP_02144	7.45e-194	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
LEFFLKOP_02145	6.23e-267	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_02146	1.21e-213	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LEFFLKOP_02147	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
LEFFLKOP_02148	5.83e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
LEFFLKOP_02149	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
LEFFLKOP_02150	3.01e-165	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
LEFFLKOP_02151	1.09e-224	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
LEFFLKOP_02152	2.32e-126	yqjB	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_02154	7.17e-99	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
LEFFLKOP_02155	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LEFFLKOP_02156	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
LEFFLKOP_02157	6.93e-181	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
LEFFLKOP_02158	1.95e-183	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEFFLKOP_02159	1.77e-32	yqzJ	-	-	-	-	-	-	-
LEFFLKOP_02160	2.72e-301	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEFFLKOP_02161	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LEFFLKOP_02162	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LEFFLKOP_02163	3.64e-220	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LEFFLKOP_02164	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
LEFFLKOP_02165	3.86e-188	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LEFFLKOP_02166	1.72e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LEFFLKOP_02167	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
LEFFLKOP_02168	4.62e-188	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEFFLKOP_02169	3.14e-227	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
LEFFLKOP_02170	6.89e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
LEFFLKOP_02171	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
LEFFLKOP_02172	6.6e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
LEFFLKOP_02173	7.43e-93	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEFFLKOP_02175	6.83e-288	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
LEFFLKOP_02177	4.03e-304	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEFFLKOP_02178	1.87e-65	yqiX	-	-	S	-	-	-	YolD-like protein
LEFFLKOP_02179	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
LEFFLKOP_02180	5.51e-79	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
LEFFLKOP_02181	2.89e-251	yqkA	-	-	K	-	-	-	GrpB protein
LEFFLKOP_02182	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
LEFFLKOP_02183	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
LEFFLKOP_02184	4.29e-227	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
LEFFLKOP_02185	1.78e-29	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
LEFFLKOP_02186	9.26e-218	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
LEFFLKOP_02187	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
LEFFLKOP_02188	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
LEFFLKOP_02189	2.62e-283	yqxK	-	-	L	-	-	-	DNA helicase
LEFFLKOP_02190	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_02191	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
LEFFLKOP_02192	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
LEFFLKOP_02193	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
LEFFLKOP_02194	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
LEFFLKOP_02195	3.73e-44	yqkK	-	-	-	-	-	-	-
LEFFLKOP_02196	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LEFFLKOP_02197	2.64e-103	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
LEFFLKOP_02198	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
LEFFLKOP_02199	3.91e-214	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
LEFFLKOP_02200	6.8e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LEFFLKOP_02201	5.66e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LEFFLKOP_02202	2.89e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
LEFFLKOP_02203	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
LEFFLKOP_02204	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LEFFLKOP_02205	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEFFLKOP_02206	1.15e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
LEFFLKOP_02207	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
LEFFLKOP_02208	5.52e-101	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
LEFFLKOP_02209	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
LEFFLKOP_02210	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
LEFFLKOP_02211	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
LEFFLKOP_02212	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
LEFFLKOP_02213	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LEFFLKOP_02214	2.67e-193	ypuA	-	-	S	-	-	-	Secreted protein
LEFFLKOP_02215	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEFFLKOP_02217	1.61e-16	-	-	-	S	-	-	-	SNARE associated Golgi protein
LEFFLKOP_02218	7.41e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
LEFFLKOP_02219	4.99e-127	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
LEFFLKOP_02220	5.98e-72	ypuD	-	-	-	-	-	-	-
LEFFLKOP_02221	7.21e-261	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LEFFLKOP_02222	2.5e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
LEFFLKOP_02223	1.48e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LEFFLKOP_02224	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LEFFLKOP_02225	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEFFLKOP_02226	3.57e-120	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
LEFFLKOP_02227	4.45e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LEFFLKOP_02228	2.85e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LEFFLKOP_02229	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
LEFFLKOP_02230	4.11e-273	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
LEFFLKOP_02231	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
LEFFLKOP_02232	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
LEFFLKOP_02233	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
LEFFLKOP_02234	1.5e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LEFFLKOP_02235	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
LEFFLKOP_02236	1.34e-278	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LEFFLKOP_02237	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEFFLKOP_02238	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_02239	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
LEFFLKOP_02240	4.91e-246	rsiX	-	-	-	-	-	-	-
LEFFLKOP_02241	4.79e-174	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LEFFLKOP_02242	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEFFLKOP_02243	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LEFFLKOP_02244	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
LEFFLKOP_02245	5.67e-258	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
LEFFLKOP_02246	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
LEFFLKOP_02247	3.55e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
LEFFLKOP_02248	1.44e-123	ypbE	-	-	M	-	-	-	Lysin motif
LEFFLKOP_02249	4.08e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
LEFFLKOP_02250	6.15e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
LEFFLKOP_02251	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LEFFLKOP_02252	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
LEFFLKOP_02253	6.04e-223	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
LEFFLKOP_02254	4.33e-154	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
LEFFLKOP_02255	1.99e-207	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
LEFFLKOP_02256	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
LEFFLKOP_02257	2.2e-142	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
LEFFLKOP_02258	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
LEFFLKOP_02259	2.36e-145	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
LEFFLKOP_02260	7.8e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
LEFFLKOP_02261	1.39e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LEFFLKOP_02262	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
LEFFLKOP_02263	3.87e-134	yphA	-	-	-	-	-	-	-
LEFFLKOP_02264	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
LEFFLKOP_02265	2.06e-38	ypzH	-	-	-	-	-	-	-
LEFFLKOP_02266	5.72e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
LEFFLKOP_02267	2.2e-231	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
LEFFLKOP_02268	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
LEFFLKOP_02269	1.5e-176	yphF	-	-	-	-	-	-	-
LEFFLKOP_02270	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LEFFLKOP_02271	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEFFLKOP_02272	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
LEFFLKOP_02273	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LEFFLKOP_02274	8.72e-178	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LEFFLKOP_02275	3.84e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LEFFLKOP_02276	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
LEFFLKOP_02277	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LEFFLKOP_02278	2.13e-182	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
LEFFLKOP_02279	5.88e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LEFFLKOP_02280	3.86e-261	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LEFFLKOP_02281	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LEFFLKOP_02282	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LEFFLKOP_02283	6.08e-230	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LEFFLKOP_02284	1.2e-144	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
LEFFLKOP_02285	2.14e-148	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
LEFFLKOP_02286	8.95e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LEFFLKOP_02287	3.82e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LEFFLKOP_02288	1.5e-257	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LEFFLKOP_02289	1.41e-263	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
LEFFLKOP_02290	6.68e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LEFFLKOP_02291	8.74e-298	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
LEFFLKOP_02292	7.45e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
LEFFLKOP_02293	2.26e-99	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
LEFFLKOP_02294	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
LEFFLKOP_02295	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
LEFFLKOP_02296	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
LEFFLKOP_02297	1.63e-125	ypjA	-	-	S	-	-	-	membrane
LEFFLKOP_02298	3.96e-182	ypjB	-	-	S	-	-	-	sporulation protein
LEFFLKOP_02299	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
LEFFLKOP_02300	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
LEFFLKOP_02301	6.89e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LEFFLKOP_02302	1.52e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
LEFFLKOP_02303	1.89e-166	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
LEFFLKOP_02304	2.34e-265	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
LEFFLKOP_02305	3.7e-279	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LEFFLKOP_02306	4.87e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LEFFLKOP_02307	4.85e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LEFFLKOP_02308	4.31e-197	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LEFFLKOP_02309	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LEFFLKOP_02310	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
LEFFLKOP_02311	6.21e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
LEFFLKOP_02312	2.27e-103	ypmB	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_02313	4.37e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
LEFFLKOP_02314	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
LEFFLKOP_02315	1.9e-164	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
LEFFLKOP_02316	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LEFFLKOP_02317	1.17e-120	ypoC	-	-	-	-	-	-	-
LEFFLKOP_02318	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
LEFFLKOP_02319	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEFFLKOP_02320	4.36e-239	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
LEFFLKOP_02323	3.11e-09	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
LEFFLKOP_02324	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
LEFFLKOP_02325	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
LEFFLKOP_02326	5.06e-94	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
LEFFLKOP_02327	2.13e-109	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
LEFFLKOP_02328	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LEFFLKOP_02329	2.07e-300	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
LEFFLKOP_02330	9.4e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
LEFFLKOP_02331	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LEFFLKOP_02332	2.84e-286	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
LEFFLKOP_02334	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
LEFFLKOP_02335	2.05e-179	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEFFLKOP_02336	2.96e-203	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LEFFLKOP_02337	1.19e-234	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
LEFFLKOP_02338	2.83e-237	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
LEFFLKOP_02339	5.97e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
LEFFLKOP_02340	5.8e-224	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
LEFFLKOP_02341	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LEFFLKOP_02342	8.16e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LEFFLKOP_02343	1.22e-291	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
LEFFLKOP_02344	4.36e-264	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
LEFFLKOP_02345	4.73e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
LEFFLKOP_02347	0.0	ypbR	-	-	S	-	-	-	Dynamin family
LEFFLKOP_02348	4.07e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
LEFFLKOP_02349	1.08e-11	-	-	-	-	-	-	-	-
LEFFLKOP_02350	9.22e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
LEFFLKOP_02351	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
LEFFLKOP_02352	1.54e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
LEFFLKOP_02353	3.27e-136	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LEFFLKOP_02354	3.16e-160	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
LEFFLKOP_02355	1.54e-37	ypeQ	-	-	S	-	-	-	Zinc-finger
LEFFLKOP_02356	1.5e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
LEFFLKOP_02357	1.17e-22	degR	-	-	-	-	-	-	-
LEFFLKOP_02358	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
LEFFLKOP_02359	3.67e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LEFFLKOP_02360	1.49e-225	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LEFFLKOP_02361	4.28e-112	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
LEFFLKOP_02362	3.69e-135	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
LEFFLKOP_02363	4.68e-203	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
LEFFLKOP_02364	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
LEFFLKOP_02365	1.61e-97	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
LEFFLKOP_02366	3.28e-182	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
LEFFLKOP_02367	3.47e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
LEFFLKOP_02368	8.91e-121	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
LEFFLKOP_02369	9.92e-201	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEFFLKOP_02370	9.58e-122	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LEFFLKOP_02371	8.12e-144	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LEFFLKOP_02372	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
LEFFLKOP_02373	8.1e-236	yplP	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_02374	3.64e-310	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LEFFLKOP_02375	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
LEFFLKOP_02376	2.77e-140	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LEFFLKOP_02377	1.28e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
LEFFLKOP_02378	6.8e-129	ypmS	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_02379	2.13e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
LEFFLKOP_02380	9.99e-290	mepA	-	-	V	-	-	-	MATE efflux family protein
LEFFLKOP_02381	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
LEFFLKOP_02382	1.4e-132	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEFFLKOP_02383	7.13e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
LEFFLKOP_02384	4.75e-157	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
LEFFLKOP_02385	2.31e-279	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
LEFFLKOP_02386	4.7e-237	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
LEFFLKOP_02387	1.12e-85	cgeA	-	-	-	ko:K06319	-	ko00000	-
LEFFLKOP_02388	3.04e-59	cgeC	-	-	-	ko:K06321	-	ko00000	-
LEFFLKOP_02389	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
LEFFLKOP_02390	9.78e-185	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
LEFFLKOP_02392	2.34e-315	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEFFLKOP_02393	3.27e-159	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LEFFLKOP_02394	2.71e-152	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LEFFLKOP_02395	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
LEFFLKOP_02396	1.84e-197	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
LEFFLKOP_02397	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
LEFFLKOP_02398	1.4e-62	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
LEFFLKOP_02399	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
LEFFLKOP_02400	1.29e-159	yodN	-	-	-	-	-	-	-
LEFFLKOP_02402	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
LEFFLKOP_02403	2.14e-133	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
LEFFLKOP_02404	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
LEFFLKOP_02405	2.08e-12	-	-	-	-	-	-	-	-
LEFFLKOP_02406	1.19e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
LEFFLKOP_02407	1.33e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
LEFFLKOP_02408	8.39e-42	yodI	-	-	-	-	-	-	-
LEFFLKOP_02409	3.69e-167	yodH	-	-	Q	-	-	-	Methyltransferase
LEFFLKOP_02410	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
LEFFLKOP_02411	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEFFLKOP_02412	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
LEFFLKOP_02413	3.24e-221	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
LEFFLKOP_02414	8.86e-145	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
LEFFLKOP_02415	1.11e-139	yodC	-	-	C	-	-	-	nitroreductase
LEFFLKOP_02416	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
LEFFLKOP_02417	3.97e-84	iolK	-	-	S	-	-	-	tautomerase
LEFFLKOP_02418	1.6e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
LEFFLKOP_02419	5.59e-14	-	-	-	-	-	-	-	-
LEFFLKOP_02420	7.69e-100	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
LEFFLKOP_02421	2.84e-208	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
LEFFLKOP_02422	1.07e-57	-	-	-	-	-	-	-	-
LEFFLKOP_02423	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
LEFFLKOP_02424	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
LEFFLKOP_02425	1.01e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEFFLKOP_02426	5.9e-313	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
LEFFLKOP_02428	4.31e-141	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEFFLKOP_02429	5.62e-294	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
LEFFLKOP_02430	2.5e-265	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
LEFFLKOP_02431	6.01e-141	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LEFFLKOP_02432	2.69e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
LEFFLKOP_02433	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
LEFFLKOP_02434	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LEFFLKOP_02435	3.02e-263	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LEFFLKOP_02436	7.79e-213	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
LEFFLKOP_02437	6.18e-300	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LEFFLKOP_02438	6.49e-210	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
LEFFLKOP_02439	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
LEFFLKOP_02440	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
LEFFLKOP_02441	1.91e-42	yozC	-	-	-	-	-	-	-
LEFFLKOP_02442	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
LEFFLKOP_02443	1.83e-49	yocN	-	-	-	-	-	-	-
LEFFLKOP_02444	2.94e-55	yozN	-	-	-	-	-	-	-
LEFFLKOP_02445	6.6e-115	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
LEFFLKOP_02446	5.79e-43	-	-	-	-	-	-	-	-
LEFFLKOP_02447	3.02e-70	yocL	-	-	-	-	-	-	-
LEFFLKOP_02448	1.42e-107	yocK	-	-	T	-	-	-	general stress protein
LEFFLKOP_02449	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LEFFLKOP_02450	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
LEFFLKOP_02451	2.89e-175	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
LEFFLKOP_02452	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEFFLKOP_02453	3.51e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_02454	5.67e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
LEFFLKOP_02455	3.19e-239	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
LEFFLKOP_02456	1.08e-121	yocC	-	-	-	-	-	-	-
LEFFLKOP_02457	2.6e-185	-	-	-	-	-	-	-	-
LEFFLKOP_02458	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
LEFFLKOP_02459	9.39e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LEFFLKOP_02460	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
LEFFLKOP_02461	4.1e-118	yobW	-	-	-	-	-	-	-
LEFFLKOP_02462	1.09e-224	yobV	-	-	K	-	-	-	WYL domain
LEFFLKOP_02463	8.64e-112	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
LEFFLKOP_02464	1.29e-167	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
LEFFLKOP_02465	3.09e-127	yobS	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_02466	2.93e-180	-	-	-	J	-	-	-	FR47-like protein
LEFFLKOP_02467	1.18e-171	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
LEFFLKOP_02468	1.75e-69	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
LEFFLKOP_02469	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
LEFFLKOP_02470	1.37e-117	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
LEFFLKOP_02471	1.52e-08	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
LEFFLKOP_02472	1.95e-26	-	-	-	-	-	-	-	-
LEFFLKOP_02474	1.12e-134	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
LEFFLKOP_02476	1.1e-23	-	-	-	-	-	-	-	-
LEFFLKOP_02477	3.23e-86	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
LEFFLKOP_02479	1.21e-149	-	-	-	-	-	-	-	-
LEFFLKOP_02480	1.72e-26	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
LEFFLKOP_02482	1.84e-11	-	-	-	K	-	-	-	Helix-turn-helix
LEFFLKOP_02483	6.27e-51	-	-	-	S	-	-	-	TM2 domain
LEFFLKOP_02484	7.53e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
LEFFLKOP_02485	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
LEFFLKOP_02488	1.04e-214	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
LEFFLKOP_02489	1.7e-147	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
LEFFLKOP_02490	1.89e-100	yoaW	-	-	-	-	-	-	-
LEFFLKOP_02491	3.7e-201	yoaV	-	-	EG	-	-	-	EamA-like transporter family
LEFFLKOP_02492	1.11e-201	yoaU	-	-	K	-	-	-	LysR substrate binding domain
LEFFLKOP_02493	1.57e-188	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
LEFFLKOP_02494	6.07e-49	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_02495	5.34e-97	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
LEFFLKOP_02496	1.04e-217	yoaR	-	-	V	-	-	-	vancomycin resistance protein
LEFFLKOP_02497	1.87e-113	-	-	-	-	-	-	-	-
LEFFLKOP_02499	3.01e-87	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
LEFFLKOP_02500	3.86e-183	yoaP	-	-	K	-	-	-	YoaP-like
LEFFLKOP_02502	8.89e-293	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
LEFFLKOP_02505	1.2e-169	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
LEFFLKOP_02506	1.43e-252	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
LEFFLKOP_02507	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
LEFFLKOP_02508	1.24e-169	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
LEFFLKOP_02509	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
LEFFLKOP_02510	6.22e-308	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
LEFFLKOP_02511	2.99e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
LEFFLKOP_02512	1.46e-19	-	-	-	-	-	-	-	-
LEFFLKOP_02515	7.24e-45	yoaF	-	-	-	-	-	-	-
LEFFLKOP_02516	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEFFLKOP_02517	3.36e-234	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEFFLKOP_02518	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
LEFFLKOP_02519	2.61e-299	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
LEFFLKOP_02520	1.63e-122	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LEFFLKOP_02521	1.04e-173	yoxB	-	-	-	-	-	-	-
LEFFLKOP_02522	1.34e-51	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
LEFFLKOP_02523	3.77e-158	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
LEFFLKOP_02524	7.32e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LEFFLKOP_02525	1.58e-184	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEFFLKOP_02526	3.86e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEFFLKOP_02527	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_02528	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
LEFFLKOP_02529	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LEFFLKOP_02530	4.18e-237	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LEFFLKOP_02531	3.57e-200	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_02532	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
LEFFLKOP_02533	4.71e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
LEFFLKOP_02534	1.14e-124	-	-	-	L	-	-	-	Integrase
LEFFLKOP_02536	7.14e-128	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
LEFFLKOP_02537	9.8e-313	yoeA	-	-	V	-	-	-	MATE efflux family protein
LEFFLKOP_02538	7.21e-236	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
LEFFLKOP_02539	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
LEFFLKOP_02540	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEFFLKOP_02541	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEFFLKOP_02542	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEFFLKOP_02543	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEFFLKOP_02544	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
LEFFLKOP_02545	2.48e-83	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
LEFFLKOP_02546	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
LEFFLKOP_02547	7.28e-266	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
LEFFLKOP_02548	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEFFLKOP_02549	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
LEFFLKOP_02550	1.98e-40	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
LEFFLKOP_02551	1.36e-211	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
LEFFLKOP_02552	3.49e-174	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
LEFFLKOP_02553	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LEFFLKOP_02554	7.39e-296	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
LEFFLKOP_02555	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
LEFFLKOP_02556	7.53e-208	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
LEFFLKOP_02557	4.06e-102	yngA	-	-	S	-	-	-	membrane
LEFFLKOP_02558	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
LEFFLKOP_02559	9.85e-317	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
LEFFLKOP_02561	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
LEFFLKOP_02562	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
LEFFLKOP_02563	1.06e-75	ynfC	-	-	-	-	-	-	-
LEFFLKOP_02564	1.82e-18	-	-	-	-	-	-	-	-
LEFFLKOP_02565	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEFFLKOP_02566	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEFFLKOP_02567	1.21e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
LEFFLKOP_02568	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LEFFLKOP_02569	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
LEFFLKOP_02570	5.48e-70	yneQ	-	-	-	-	-	-	-
LEFFLKOP_02571	2.72e-93	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
LEFFLKOP_02572	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
LEFFLKOP_02574	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
LEFFLKOP_02575	2.53e-118	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LEFFLKOP_02576	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LEFFLKOP_02577	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
LEFFLKOP_02578	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
LEFFLKOP_02579	2.35e-84	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
LEFFLKOP_02580	2.79e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
LEFFLKOP_02581	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
LEFFLKOP_02582	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
LEFFLKOP_02583	4.13e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
LEFFLKOP_02584	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
LEFFLKOP_02585	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
LEFFLKOP_02586	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
LEFFLKOP_02587	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LEFFLKOP_02588	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
LEFFLKOP_02589	2.29e-144	yneB	-	-	L	-	-	-	resolvase
LEFFLKOP_02590	8.5e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LEFFLKOP_02591	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LEFFLKOP_02592	4.44e-104	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LEFFLKOP_02593	1.32e-96	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
LEFFLKOP_02594	3.26e-175	yndL	-	-	S	-	-	-	Replication protein
LEFFLKOP_02596	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
LEFFLKOP_02597	6.98e-149	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
LEFFLKOP_02598	2.52e-196	yndG	-	-	S	-	-	-	DoxX-like family
LEFFLKOP_02599	2.27e-288	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
LEFFLKOP_02600	7.36e-75	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
LEFFLKOP_02601	8.95e-129	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
LEFFLKOP_02602	4.18e-42	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
LEFFLKOP_02605	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
LEFFLKOP_02606	8.92e-96	-	-	-	-	-	-	-	-
LEFFLKOP_02607	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
LEFFLKOP_02610	2.02e-168	-	-	-	S	-	-	-	Domain of unknown function, YrpD
LEFFLKOP_02611	9.21e-209	-	-	-	S	-	-	-	Thymidylate synthase
LEFFLKOP_02614	7.54e-22	-	-	-	-	-	-	-	-
LEFFLKOP_02615	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
LEFFLKOP_02616	5.49e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
LEFFLKOP_02617	5.06e-280	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEFFLKOP_02618	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEFFLKOP_02619	7.18e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
LEFFLKOP_02620	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
LEFFLKOP_02621	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
LEFFLKOP_02622	1.18e-273	xylR	-	-	GK	-	-	-	ROK family
LEFFLKOP_02623	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
LEFFLKOP_02624	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
LEFFLKOP_02625	5.04e-109	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
LEFFLKOP_02628	2.12e-140	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
LEFFLKOP_02629	3.39e-31	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
LEFFLKOP_02630	6.65e-11	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
LEFFLKOP_02631	1.99e-94	-	-	-	S	-	-	-	CAAX protease self-immunity
LEFFLKOP_02633	4.28e-128	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
LEFFLKOP_02635	1.81e-273	-	-	-	H	-	-	-	N-terminal domain of galactosyltransferase
LEFFLKOP_02636	1.74e-247	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
LEFFLKOP_02637	1.17e-155	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
LEFFLKOP_02638	9.6e-120	-	-	-	M	-	-	-	Glycosyltransferase like family
LEFFLKOP_02648	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LEFFLKOP_02649	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LEFFLKOP_02650	3.72e-238	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
LEFFLKOP_02651	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
LEFFLKOP_02652	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LEFFLKOP_02653	1.56e-98	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
LEFFLKOP_02654	1.29e-260	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
LEFFLKOP_02655	1.01e-275	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
LEFFLKOP_02656	2.82e-262	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
LEFFLKOP_02658	1.06e-299	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
LEFFLKOP_02659	4.3e-228	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
LEFFLKOP_02660	2.03e-310	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEFFLKOP_02661	1.34e-193	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
LEFFLKOP_02662	1.75e-168	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
LEFFLKOP_02663	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
LEFFLKOP_02664	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LEFFLKOP_02665	1.15e-195	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LEFFLKOP_02666	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LEFFLKOP_02667	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LEFFLKOP_02668	7.07e-273	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LEFFLKOP_02669	1.13e-218	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
LEFFLKOP_02670	1.83e-180	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LEFFLKOP_02671	4.7e-299	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LEFFLKOP_02672	9.65e-194	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
LEFFLKOP_02673	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
LEFFLKOP_02674	2.96e-241	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LEFFLKOP_02675	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
LEFFLKOP_02676	4.14e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
LEFFLKOP_02677	1.27e-133	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
LEFFLKOP_02678	3.41e-112	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LEFFLKOP_02679	2.27e-93	ytkA	-	-	S	-	-	-	YtkA-like
LEFFLKOP_02681	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
LEFFLKOP_02682	6.47e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
LEFFLKOP_02683	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
LEFFLKOP_02684	1.09e-182	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LEFFLKOP_02685	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
LEFFLKOP_02686	2.77e-242	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LEFFLKOP_02687	6.67e-191	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LEFFLKOP_02688	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
LEFFLKOP_02689	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LEFFLKOP_02690	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LEFFLKOP_02691	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
LEFFLKOP_02692	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
LEFFLKOP_02693	8.35e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LEFFLKOP_02694	2.33e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
LEFFLKOP_02695	2.29e-274	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
LEFFLKOP_02696	1.59e-135	ytqB	-	-	J	-	-	-	Putative rRNA methylase
LEFFLKOP_02697	2.35e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
LEFFLKOP_02698	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
LEFFLKOP_02700	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
LEFFLKOP_02701	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_02702	7.66e-196	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
LEFFLKOP_02703	5.96e-180	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
LEFFLKOP_02704	1.02e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_02705	3.99e-296	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
LEFFLKOP_02706	9.07e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEFFLKOP_02707	3.06e-237	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
LEFFLKOP_02708	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_02709	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
LEFFLKOP_02710	2.32e-77	yttA	-	-	S	-	-	-	Pfam Transposase IS66
LEFFLKOP_02711	2.45e-268	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
LEFFLKOP_02712	1.56e-182	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LEFFLKOP_02713	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
LEFFLKOP_02714	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
LEFFLKOP_02715	2.03e-67	ytwF	-	-	P	-	-	-	Sulfurtransferase
LEFFLKOP_02716	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
LEFFLKOP_02717	1.48e-183	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
LEFFLKOP_02718	4.75e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEFFLKOP_02719	2.58e-312	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
LEFFLKOP_02720	3.75e-243	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_02721	2.66e-218	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
LEFFLKOP_02722	5.08e-191	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LEFFLKOP_02723	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LEFFLKOP_02724	3.15e-276	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LEFFLKOP_02725	1.28e-157	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LEFFLKOP_02726	2.64e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LEFFLKOP_02727	4.38e-286	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
LEFFLKOP_02728	2.21e-178	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
LEFFLKOP_02729	6.19e-193	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
LEFFLKOP_02730	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
LEFFLKOP_02731	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_02732	2.27e-221	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
LEFFLKOP_02733	3.24e-276	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
LEFFLKOP_02734	2.37e-94	yteS	-	-	G	-	-	-	transport
LEFFLKOP_02735	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
LEFFLKOP_02736	3.97e-152	yteU	-	-	S	-	-	-	Integral membrane protein
LEFFLKOP_02737	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
LEFFLKOP_02738	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
LEFFLKOP_02739	3.22e-305	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
LEFFLKOP_02740	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEFFLKOP_02741	7.43e-170	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
LEFFLKOP_02742	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
LEFFLKOP_02743	5.66e-168	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
LEFFLKOP_02744	3.51e-255	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
LEFFLKOP_02745	1.73e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
LEFFLKOP_02746	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
LEFFLKOP_02747	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
LEFFLKOP_02748	1.56e-132	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LEFFLKOP_02749	4.92e-212	ytlQ	-	-	-	-	-	-	-
LEFFLKOP_02750	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
LEFFLKOP_02751	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
LEFFLKOP_02752	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
LEFFLKOP_02753	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
LEFFLKOP_02754	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LEFFLKOP_02755	5.09e-192	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
LEFFLKOP_02756	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
LEFFLKOP_02757	1.17e-67	ytzB	-	-	S	-	-	-	small secreted protein
LEFFLKOP_02758	3.71e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
LEFFLKOP_02759	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
LEFFLKOP_02760	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
LEFFLKOP_02761	2.06e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
LEFFLKOP_02762	1.78e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEFFLKOP_02763	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
LEFFLKOP_02764	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
LEFFLKOP_02765	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LEFFLKOP_02766	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
LEFFLKOP_02767	3.17e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
LEFFLKOP_02768	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LEFFLKOP_02769	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
LEFFLKOP_02770	6.84e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
LEFFLKOP_02771	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
LEFFLKOP_02772	2.65e-292	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
LEFFLKOP_02773	6.16e-152	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
LEFFLKOP_02774	2.84e-155	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LEFFLKOP_02775	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LEFFLKOP_02776	1.85e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEFFLKOP_02778	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LEFFLKOP_02779	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
LEFFLKOP_02780	1.13e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
LEFFLKOP_02781	1.2e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_02782	1.25e-196	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LEFFLKOP_02783	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LEFFLKOP_02784	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
LEFFLKOP_02785	1.07e-263	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
LEFFLKOP_02786	6.26e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEFFLKOP_02787	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
LEFFLKOP_02788	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LEFFLKOP_02789	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
LEFFLKOP_02790	2.92e-190	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEFFLKOP_02791	2.79e-229	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
LEFFLKOP_02792	4.08e-112	yteJ	-	-	S	-	-	-	RDD family
LEFFLKOP_02793	8.34e-149	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
LEFFLKOP_02794	1.06e-94	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
LEFFLKOP_02795	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LEFFLKOP_02796	3.78e-224	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
LEFFLKOP_02797	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEFFLKOP_02798	3.31e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
LEFFLKOP_02799	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
LEFFLKOP_02800	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
LEFFLKOP_02802	1.98e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEFFLKOP_02803	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
LEFFLKOP_02804	1.37e-220	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
LEFFLKOP_02805	8.39e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
LEFFLKOP_02806	7.48e-194	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
LEFFLKOP_02807	4.49e-191	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
LEFFLKOP_02808	1.66e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
LEFFLKOP_02809	7.89e-154	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
LEFFLKOP_02810	5.43e-182	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
LEFFLKOP_02811	6.9e-234	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEFFLKOP_02812	1.24e-61	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
LEFFLKOP_02813	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEFFLKOP_02814	2.31e-164	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
LEFFLKOP_02815	1.58e-301	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
LEFFLKOP_02816	6.14e-204	ytnM	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
LEFFLKOP_02817	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
LEFFLKOP_02818	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
LEFFLKOP_02819	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
LEFFLKOP_02820	1.15e-39	-	-	-	-	-	-	-	-
LEFFLKOP_02821	5.12e-112	ytrI	-	-	-	-	-	-	-
LEFFLKOP_02822	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
LEFFLKOP_02823	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
LEFFLKOP_02824	2.01e-285	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
LEFFLKOP_02825	2.17e-208	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LEFFLKOP_02826	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LEFFLKOP_02827	1.62e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LEFFLKOP_02828	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
LEFFLKOP_02829	2.71e-81	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
LEFFLKOP_02830	2.73e-245	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
LEFFLKOP_02831	4.46e-93	ytwI	-	-	S	-	-	-	membrane
LEFFLKOP_02832	1.17e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
LEFFLKOP_02833	2.28e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
LEFFLKOP_02834	1.04e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
LEFFLKOP_02835	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEFFLKOP_02836	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
LEFFLKOP_02837	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEFFLKOP_02838	3.88e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LEFFLKOP_02839	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
LEFFLKOP_02840	2.82e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LEFFLKOP_02841	4.54e-205	ytbE	-	-	S	-	-	-	reductase
LEFFLKOP_02842	1.12e-254	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
LEFFLKOP_02843	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_02844	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEFFLKOP_02845	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LEFFLKOP_02846	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LEFFLKOP_02847	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
LEFFLKOP_02848	3.5e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
LEFFLKOP_02849	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
LEFFLKOP_02850	5.98e-206	ytxC	-	-	S	-	-	-	YtxC-like family
LEFFLKOP_02851	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEFFLKOP_02852	1.2e-190	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
LEFFLKOP_02853	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_02854	3.39e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
LEFFLKOP_02855	2.08e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LEFFLKOP_02856	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LEFFLKOP_02858	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LEFFLKOP_02859	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
LEFFLKOP_02860	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LEFFLKOP_02861	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
LEFFLKOP_02862	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
LEFFLKOP_02863	2.93e-260	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
LEFFLKOP_02864	9.92e-242	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
LEFFLKOP_02865	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
LEFFLKOP_02866	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
LEFFLKOP_02867	1.99e-169	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LEFFLKOP_02868	6.06e-187	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
LEFFLKOP_02869	1.07e-281	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LEFFLKOP_02870	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
LEFFLKOP_02871	6.77e-219	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
LEFFLKOP_02872	4.28e-190	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
LEFFLKOP_02873	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
LEFFLKOP_02874	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
LEFFLKOP_02875	8.8e-55	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
LEFFLKOP_02876	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
LEFFLKOP_02877	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
LEFFLKOP_02878	2.51e-260	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
LEFFLKOP_02879	7.54e-44	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
LEFFLKOP_02880	3.13e-171	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEFFLKOP_02881	1.81e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LEFFLKOP_02882	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEFFLKOP_02883	2.96e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEFFLKOP_02884	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LEFFLKOP_02885	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
LEFFLKOP_02886	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
LEFFLKOP_02887	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LEFFLKOP_02888	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
LEFFLKOP_02889	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEFFLKOP_02890	2.44e-130	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_02891	2.2e-176	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
LEFFLKOP_02892	2.58e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
LEFFLKOP_02893	1.23e-227	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
LEFFLKOP_02895	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
LEFFLKOP_02896	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
LEFFLKOP_02897	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LEFFLKOP_02898	3.96e-275	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
LEFFLKOP_02899	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
LEFFLKOP_02900	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
LEFFLKOP_02901	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
LEFFLKOP_02902	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
LEFFLKOP_02903	1.79e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
LEFFLKOP_02904	6.14e-25	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_02905	3.35e-63	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
LEFFLKOP_02906	2.71e-20	-	-	-	-	-	-	-	-
LEFFLKOP_02907	1.04e-32	-	-	-	K	-	-	-	sequence-specific DNA binding
LEFFLKOP_02908	2.76e-18	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
LEFFLKOP_02910	2.6e-56	-	-	-	S	-	-	-	DNA binding
LEFFLKOP_02911	4.08e-106	-	-	-	-	-	-	-	-
LEFFLKOP_02916	4.58e-141	-	-	-	S	-	-	-	YqaJ-like viral recombinase domain
LEFFLKOP_02917	8.2e-115	recT	-	-	L	ko:K07455	-	ko00000,ko03400	Recombinational DNA repair protein (RecE pathway)
LEFFLKOP_02918	1.37e-45	yqaL	-	-	L	-	-	-	DnaD domain protein
LEFFLKOP_02919	6.12e-152	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
LEFFLKOP_02921	1.62e-13	-	-	-	S	-	-	-	YopX protein
LEFFLKOP_02923	1.05e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
LEFFLKOP_02925	1.85e-29	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
LEFFLKOP_02930	3.04e-12	-	-	-	-	-	-	-	-
LEFFLKOP_02931	2.15e-90	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LEFFLKOP_02933	2.95e-23	-	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_02937	1.37e-110	yqaS	-	-	L	-	-	-	DNA packaging
LEFFLKOP_02938	4.64e-236	-	-	-	S	-	-	-	Terminase-like family
LEFFLKOP_02939	1.21e-194	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
LEFFLKOP_02941	4.59e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
LEFFLKOP_02942	8.27e-157	-	-	-	S	-	-	-	Phage capsid family
LEFFLKOP_02944	3.46e-41	-	-	-	S	-	-	-	Phage Mu protein F like protein
LEFFLKOP_02946	2.44e-61	-	-	-	-	-	-	-	-
LEFFLKOP_02948	1.46e-40	-	-	-	-	-	-	-	-
LEFFLKOP_02949	1.61e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
LEFFLKOP_02950	9.14e-46	-	-	-	-	-	-	-	-
LEFFLKOP_02951	4.31e-21	-	-	-	-	-	-	-	-
LEFFLKOP_02952	7.39e-173	-	-	-	N	-	-	-	phage tail tape measure protein
LEFFLKOP_02953	6.22e-47	-	-	-	M	-	-	-	LysM domain
LEFFLKOP_02954	1.13e-41	-	-	-	-	-	-	-	-
LEFFLKOP_02955	3.69e-111	-	-	-	-	-	-	-	-
LEFFLKOP_02957	4.54e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2634)
LEFFLKOP_02958	2.44e-133	-	-	-	S	-	-	-	homolog of phage Mu protein gp47
LEFFLKOP_02959	4.28e-79	-	-	-	-	-	-	-	-
LEFFLKOP_02960	9.69e-51	-	-	-	-	-	-	-	-
LEFFLKOP_02962	2.89e-17	xkdX	-	-	-	-	-	-	-
LEFFLKOP_02963	1.95e-37	xhlA	-	-	S	-	-	-	Haemolysin XhlA
LEFFLKOP_02964	6.44e-41	xhlB	-	-	S	-	-	-	SPP1 phage holin
LEFFLKOP_02965	1.39e-138	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
LEFFLKOP_02967	2.83e-35	-	-	-	-	-	-	-	-
LEFFLKOP_02968	2.68e-56	-	-	-	S	-	-	-	YolD-like protein
LEFFLKOP_02969	2.64e-206	-	-	-	L	-	-	-	Recombinase
LEFFLKOP_02970	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
LEFFLKOP_02971	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
LEFFLKOP_02972	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
LEFFLKOP_02973	2.04e-170	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LEFFLKOP_02974	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LEFFLKOP_02975	2.34e-118	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
LEFFLKOP_02977	2.64e-178	ysnF	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_02978	1.71e-100	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
LEFFLKOP_02980	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
LEFFLKOP_02981	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
LEFFLKOP_02982	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LEFFLKOP_02983	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LEFFLKOP_02984	7.43e-256	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LEFFLKOP_02985	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LEFFLKOP_02986	2.98e-147	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LEFFLKOP_02987	3.19e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
LEFFLKOP_02988	5.13e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LEFFLKOP_02989	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LEFFLKOP_02990	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
LEFFLKOP_02991	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LEFFLKOP_02992	1.08e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
LEFFLKOP_02993	8.23e-117	ysxD	-	-	-	-	-	-	-
LEFFLKOP_02994	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LEFFLKOP_02995	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
LEFFLKOP_02996	2.19e-220	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LEFFLKOP_02997	2.49e-184	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
LEFFLKOP_02998	3.04e-232	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
LEFFLKOP_02999	3.53e-312	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
LEFFLKOP_03000	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
LEFFLKOP_03001	9.73e-252	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LEFFLKOP_03002	1.53e-35	-	-	-	-	-	-	-	-
LEFFLKOP_03003	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LEFFLKOP_03004	1.83e-314	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
LEFFLKOP_03005	1.81e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LEFFLKOP_03006	2.53e-205	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
LEFFLKOP_03007	1.66e-130	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
LEFFLKOP_03008	1.39e-161	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
LEFFLKOP_03009	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
LEFFLKOP_03010	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
LEFFLKOP_03011	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
LEFFLKOP_03012	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LEFFLKOP_03013	2.91e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
LEFFLKOP_03014	1.23e-185	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
LEFFLKOP_03015	3.74e-208	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
LEFFLKOP_03016	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
LEFFLKOP_03017	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
LEFFLKOP_03018	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
LEFFLKOP_03019	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
LEFFLKOP_03020	1.13e-307	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LEFFLKOP_03021	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
LEFFLKOP_03022	1.43e-208	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
LEFFLKOP_03023	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
LEFFLKOP_03024	1.17e-290	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
LEFFLKOP_03025	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
LEFFLKOP_03026	8.77e-203	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
LEFFLKOP_03027	1.87e-271	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LEFFLKOP_03028	2.43e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
LEFFLKOP_03029	2.55e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEFFLKOP_03030	4.1e-163	yebC	-	-	K	-	-	-	transcriptional regulatory protein
LEFFLKOP_03031	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
LEFFLKOP_03032	2.55e-67	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
LEFFLKOP_03034	2.32e-152	yrzF	-	-	T	-	-	-	serine threonine protein kinase
LEFFLKOP_03035	2.77e-248	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
LEFFLKOP_03036	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
LEFFLKOP_03037	1.85e-120	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
LEFFLKOP_03038	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LEFFLKOP_03039	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LEFFLKOP_03040	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
LEFFLKOP_03041	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LEFFLKOP_03042	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LEFFLKOP_03043	1.24e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
LEFFLKOP_03044	4.89e-95	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
LEFFLKOP_03045	5.83e-143	yrbG	-	-	S	-	-	-	membrane
LEFFLKOP_03046	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEFFLKOP_03047	5.53e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
LEFFLKOP_03048	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LEFFLKOP_03049	3.1e-112	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
LEFFLKOP_03050	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
LEFFLKOP_03051	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
LEFFLKOP_03052	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LEFFLKOP_03053	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LEFFLKOP_03054	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LEFFLKOP_03055	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
LEFFLKOP_03057	3e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
LEFFLKOP_03058	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LEFFLKOP_03059	2.29e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LEFFLKOP_03060	2.44e-303	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LEFFLKOP_03061	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_03062	3.63e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
LEFFLKOP_03063	5.64e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LEFFLKOP_03064	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
LEFFLKOP_03065	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LEFFLKOP_03066	1.44e-107	yrrD	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_03067	8.4e-42	yrzR	-	-	-	-	-	-	-
LEFFLKOP_03068	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
LEFFLKOP_03069	1.54e-138	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEFFLKOP_03070	2.66e-138	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
LEFFLKOP_03071	1.01e-184	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
LEFFLKOP_03072	8.99e-168	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
LEFFLKOP_03073	3.07e-242	yrrI	-	-	S	-	-	-	AI-2E family transporter
LEFFLKOP_03074	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LEFFLKOP_03075	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
LEFFLKOP_03076	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LEFFLKOP_03077	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
LEFFLKOP_03078	7.51e-242	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LEFFLKOP_03079	1.98e-154	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
LEFFLKOP_03080	6.3e-222	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
LEFFLKOP_03081	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
LEFFLKOP_03082	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
LEFFLKOP_03083	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEFFLKOP_03084	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
LEFFLKOP_03085	2.34e-101	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
LEFFLKOP_03086	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
LEFFLKOP_03087	3.44e-153	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
LEFFLKOP_03088	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LEFFLKOP_03089	1.36e-215	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
LEFFLKOP_03090	8.55e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
LEFFLKOP_03091	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
LEFFLKOP_03092	1.22e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
LEFFLKOP_03093	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
LEFFLKOP_03094	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
LEFFLKOP_03095	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
LEFFLKOP_03097	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
LEFFLKOP_03098	1.1e-126	yrhH	-	-	Q	-	-	-	methyltransferase
LEFFLKOP_03099	1.12e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
LEFFLKOP_03100	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
LEFFLKOP_03101	7.54e-211	-	1.1.1.136, 1.1.1.336	-	C	ko:K02472,ko:K02474,ko:K13015	ko00520,ko05111,map00520,map05111	ko00000,ko00001,ko01000,ko01005	PFAM UDP-glucose GDP-mannose dehydrogenase
LEFFLKOP_03102	2.31e-148	-	5.1.3.2, 5.1.3.20, 5.1.3.7	-	GM	ko:K01784,ko:K02473,ko:K03274	ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	NmrA-like family
LEFFLKOP_03103	6.6e-147	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
LEFFLKOP_03104	5.35e-80	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
LEFFLKOP_03105	2.25e-78	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
LEFFLKOP_03106	3.8e-121	-	-	-	Q	-	-	-	TIGRFAM amino acid adenylation domain
LEFFLKOP_03107	2.89e-54	-	-	-	I	-	-	-	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LEFFLKOP_03108	7.6e-228	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Aromatic amino acid lyase
LEFFLKOP_03109	1.27e-121	-	-	-	EF	-	-	-	ATP-grasp domain
LEFFLKOP_03110	1.25e-105	yodQ	3.5.1.16	-	E	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
LEFFLKOP_03112	4.88e-12	-	-	-	S	-	-	-	cell adhesion involved in biofilm formation
LEFFLKOP_03114	1.42e-24	yrhK	-	-	S	-	-	-	YrhK-like protein
LEFFLKOP_03115	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
LEFFLKOP_03116	9.41e-94	oatA	-	-	I	-	-	-	Acyltransferase family
LEFFLKOP_03117	9.4e-188	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
LEFFLKOP_03118	1.19e-193	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
LEFFLKOP_03119	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
LEFFLKOP_03120	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
LEFFLKOP_03121	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
LEFFLKOP_03122	2.66e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
LEFFLKOP_03123	2.19e-106	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
LEFFLKOP_03124	2.79e-166	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
LEFFLKOP_03125	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
LEFFLKOP_03126	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
LEFFLKOP_03127	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
LEFFLKOP_03128	1.32e-250	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
LEFFLKOP_03129	9.21e-25	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
LEFFLKOP_03130	8.8e-13	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
LEFFLKOP_03131	6.31e-26	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
LEFFLKOP_03132	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
LEFFLKOP_03133	6.11e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
LEFFLKOP_03134	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LEFFLKOP_03135	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
LEFFLKOP_03136	1.2e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
LEFFLKOP_03137	5.45e-86	-	-	-	E	-	-	-	Glyoxalase-like domain
LEFFLKOP_03139	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
LEFFLKOP_03140	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
LEFFLKOP_03141	2.33e-194	-	-	-	S	-	-	-	Alpha beta hydrolase
LEFFLKOP_03142	6.15e-57	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEFFLKOP_03143	9.5e-201	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LEFFLKOP_03144	1.71e-262	yraM	-	-	S	-	-	-	PrpF protein
LEFFLKOP_03145	2.97e-210	yraN	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_03146	2.16e-285	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
LEFFLKOP_03147	5.96e-240	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
LEFFLKOP_03148	3.99e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
LEFFLKOP_03149	7.31e-167	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
LEFFLKOP_03150	1.62e-63	-	-	-	S	-	-	-	YjbR
LEFFLKOP_03151	1.12e-156	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
LEFFLKOP_03152	3.1e-126	-	-	-	S	-	-	-	Flavin reductase like domain
LEFFLKOP_03153	4.98e-172	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG3959 Transketolase, N-terminal subunit
LEFFLKOP_03154	1.02e-192	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
LEFFLKOP_03155	6.21e-148	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEFFLKOP_03156	4.11e-268	-	-	-	P	-	-	-	Major Facilitator Superfamily
LEFFLKOP_03158	6.71e-128	-	-	-	K	ko:K05799	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
LEFFLKOP_03159	4.62e-160	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
LEFFLKOP_03160	9.78e-188	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
LEFFLKOP_03161	4.42e-248	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LEFFLKOP_03162	5.77e-210	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
LEFFLKOP_03163	1.17e-117	yrdA	-	-	S	-	-	-	DinB family
LEFFLKOP_03165	2.99e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
LEFFLKOP_03166	2.11e-130	yrdC	-	-	Q	-	-	-	Isochorismatase family
LEFFLKOP_03167	7.64e-290	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
LEFFLKOP_03168	1.76e-22	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
LEFFLKOP_03169	4.13e-104	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
LEFFLKOP_03170	9.34e-176	azlC	-	-	E	-	-	-	AzlC protein
LEFFLKOP_03171	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
LEFFLKOP_03172	2.03e-291	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
LEFFLKOP_03173	5.01e-41	-	-	-	C	-	-	-	COG2041 Sulfite oxidase and related enzymes
LEFFLKOP_03174	6.6e-201	-	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
LEFFLKOP_03175	1.75e-87	yodA	-	-	S	-	-	-	tautomerase
LEFFLKOP_03176	2e-211	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
LEFFLKOP_03177	7.41e-255	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
LEFFLKOP_03178	3.3e-202	-	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_03179	1.26e-218	yrdR	-	-	EG	-	-	-	EamA-like transporter family
LEFFLKOP_03180	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
LEFFLKOP_03181	8.77e-299	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
LEFFLKOP_03182	7.23e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
LEFFLKOP_03183	1.08e-268	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_03184	1.24e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
LEFFLKOP_03185	8.99e-138	yrkC	-	-	G	-	-	-	Cupin domain
LEFFLKOP_03186	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_03187	2.78e-108	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
LEFFLKOP_03188	9.3e-126	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
LEFFLKOP_03189	2.07e-263	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
LEFFLKOP_03190	3.2e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
LEFFLKOP_03191	1.9e-149	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
LEFFLKOP_03192	3.13e-104	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
LEFFLKOP_03193	9.48e-125	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
LEFFLKOP_03194	2.48e-130	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
LEFFLKOP_03195	7.53e-283	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
LEFFLKOP_03196	7.15e-164	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
LEFFLKOP_03197	7.32e-306	yrkQ	-	-	T	-	-	-	Histidine kinase
LEFFLKOP_03198	4.46e-79	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEFFLKOP_03199	2.61e-316	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
LEFFLKOP_03201	5.36e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
LEFFLKOP_03202	1.19e-176	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
LEFFLKOP_03203	2.37e-226	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEFFLKOP_03204	1.17e-225	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEFFLKOP_03205	1.26e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
LEFFLKOP_03206	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
LEFFLKOP_03207	8.14e-303	ybbC	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_03208	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
LEFFLKOP_03209	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
LEFFLKOP_03210	1.04e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFFLKOP_03211	3.01e-191	ybbH	-	-	K	-	-	-	transcriptional
LEFFLKOP_03212	1.11e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LEFFLKOP_03213	1.81e-113	ybbJ	-	-	J	-	-	-	acetyltransferase
LEFFLKOP_03214	4.19e-101	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
LEFFLKOP_03220	9.27e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
LEFFLKOP_03221	3.19e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LEFFLKOP_03222	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEFFLKOP_03223	3.41e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_03224	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LEFFLKOP_03225	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LEFFLKOP_03226	5.38e-220	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LEFFLKOP_03227	1.03e-153	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
LEFFLKOP_03228	1.06e-128	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEFFLKOP_03229	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LEFFLKOP_03230	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
LEFFLKOP_03231	3.29e-121	ybcF	-	-	P	-	-	-	carbonic anhydrase
LEFFLKOP_03232	4.6e-63	-	-	-	-	-	-	-	-
LEFFLKOP_03233	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
LEFFLKOP_03234	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
LEFFLKOP_03235	9.37e-258	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
LEFFLKOP_03237	1.21e-21	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
LEFFLKOP_03238	7.04e-139	bsaB	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
LEFFLKOP_03239	6.48e-50	spaC1	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C family protein
LEFFLKOP_03241	6.47e-176	abcA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
LEFFLKOP_03242	9.03e-230	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LEFFLKOP_03243	6.9e-158	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
LEFFLKOP_03244	1.61e-218	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
LEFFLKOP_03246	3.26e-177	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
LEFFLKOP_03247	3.67e-193	ybdN	-	-	-	-	-	-	-
LEFFLKOP_03248	4.26e-272	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
LEFFLKOP_03249	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
LEFFLKOP_03250	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
LEFFLKOP_03251	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
LEFFLKOP_03252	1.29e-193	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
LEFFLKOP_03253	1.09e-313	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
LEFFLKOP_03254	1.11e-54	ybyB	-	-	-	-	-	-	-
LEFFLKOP_03255	0.0	ybeC	-	-	E	-	-	-	amino acid
LEFFLKOP_03256	2.85e-210	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
LEFFLKOP_03257	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
LEFFLKOP_03258	3.57e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
LEFFLKOP_03259	2.1e-218	ybfA	-	-	K	-	-	-	FR47-like protein
LEFFLKOP_03260	2.36e-287	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_03262	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
LEFFLKOP_03263	5.27e-208	ybfH	-	-	EG	-	-	-	EamA-like transporter family
LEFFLKOP_03264	7.39e-188	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
LEFFLKOP_03265	2.78e-272	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LEFFLKOP_03266	1.97e-227	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
LEFFLKOP_03268	4.38e-211	-	-	-	S	-	-	-	Alpha/beta hydrolase family
LEFFLKOP_03269	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEFFLKOP_03270	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
LEFFLKOP_03271	1.45e-188	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LEFFLKOP_03272	1.58e-59	ybfN	-	-	-	-	-	-	-
LEFFLKOP_03273	7.86e-243	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
LEFFLKOP_03274	6.04e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEFFLKOP_03275	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFFLKOP_03276	7.72e-177	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LEFFLKOP_03277	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
LEFFLKOP_03279	9.84e-261	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
LEFFLKOP_03280	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
LEFFLKOP_03281	2.05e-230	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
LEFFLKOP_03282	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
LEFFLKOP_03283	9.16e-240	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
LEFFLKOP_03284	3.55e-294	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_03285	1.72e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
LEFFLKOP_03286	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
LEFFLKOP_03287	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEFFLKOP_03288	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_03289	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
LEFFLKOP_03290	4.63e-161	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
LEFFLKOP_03291	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
LEFFLKOP_03292	1.81e-224	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
LEFFLKOP_03293	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
LEFFLKOP_03294	4.02e-134	eamA1	-	-	EG	-	-	-	spore germination
LEFFLKOP_03295	3.05e-159	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEFFLKOP_03296	6.48e-216	ycbM	-	-	T	-	-	-	Histidine kinase
LEFFLKOP_03297	1.86e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_03298	8.21e-148	-	-	-	S	-	-	-	ABC-2 family transporter protein
LEFFLKOP_03299	2.21e-76	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
LEFFLKOP_03300	1.82e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
LEFFLKOP_03301	4.66e-175	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
LEFFLKOP_03302	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
LEFFLKOP_03303	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LEFFLKOP_03304	3.09e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LEFFLKOP_03305	9.85e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LEFFLKOP_03306	1.77e-261	ycbU	-	-	E	-	-	-	Selenocysteine lyase
LEFFLKOP_03307	2.51e-302	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
LEFFLKOP_03308	1.88e-131	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
LEFFLKOP_03309	2.4e-257	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LEFFLKOP_03310	4e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LEFFLKOP_03311	1.14e-73	-	-	-	S	-	-	-	RDD family
LEFFLKOP_03312	2.49e-255	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
LEFFLKOP_03313	7.2e-212	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
LEFFLKOP_03314	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
LEFFLKOP_03315	2.2e-170	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
LEFFLKOP_03316	5.64e-257	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
LEFFLKOP_03317	6.81e-222	yccK	-	-	C	-	-	-	Aldo keto reductase
LEFFLKOP_03318	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
LEFFLKOP_03319	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
LEFFLKOP_03320	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
LEFFLKOP_03321	1.08e-122	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
LEFFLKOP_03322	2.86e-248	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
LEFFLKOP_03323	1.96e-179	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
LEFFLKOP_03324	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
LEFFLKOP_03325	1.86e-219	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
LEFFLKOP_03326	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LEFFLKOP_03327	4.63e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LEFFLKOP_03328	4.01e-236	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEFFLKOP_03329	1.78e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
LEFFLKOP_03330	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
LEFFLKOP_03331	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
LEFFLKOP_03332	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
LEFFLKOP_03333	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
LEFFLKOP_03334	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
LEFFLKOP_03335	1.1e-277	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
LEFFLKOP_03336	1.07e-263	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
LEFFLKOP_03337	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
LEFFLKOP_03338	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
LEFFLKOP_03339	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
LEFFLKOP_03340	2.01e-210	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
LEFFLKOP_03341	8.96e-273	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
LEFFLKOP_03342	0.0	ycgA	-	-	S	-	-	-	Membrane
LEFFLKOP_03343	5.48e-105	ycgB	-	-	-	-	-	-	-
LEFFLKOP_03344	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
LEFFLKOP_03345	1.19e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
LEFFLKOP_03346	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
LEFFLKOP_03347	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
LEFFLKOP_03348	3.7e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
LEFFLKOP_03349	6.42e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
LEFFLKOP_03350	1.85e-195	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
LEFFLKOP_03351	0.0	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
LEFFLKOP_03352	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
LEFFLKOP_03353	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LEFFLKOP_03354	1.31e-140	tmrB	-	-	S	-	-	-	AAA domain
LEFFLKOP_03355	1.05e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LEFFLKOP_03356	2.06e-183	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
LEFFLKOP_03357	3.26e-227	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
LEFFLKOP_03358	1.1e-231	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
LEFFLKOP_03359	3.69e-185	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
LEFFLKOP_03360	2.1e-217	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
LEFFLKOP_03361	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
LEFFLKOP_03362	1.05e-315	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEFFLKOP_03363	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
LEFFLKOP_03364	2.12e-192	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
LEFFLKOP_03365	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
LEFFLKOP_03366	3.44e-202	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
LEFFLKOP_03367	8.53e-245	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
LEFFLKOP_03368	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
LEFFLKOP_03369	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
LEFFLKOP_03370	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LEFFLKOP_03371	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEFFLKOP_03372	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
LEFFLKOP_03373	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
LEFFLKOP_03374	1.08e-215	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
LEFFLKOP_03375	1.04e-140	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
LEFFLKOP_03376	3.76e-288	yciC	-	-	S	-	-	-	GTPases (G3E family)
LEFFLKOP_03377	9.69e-149	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
LEFFLKOP_03378	7.26e-185	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
LEFFLKOP_03380	1.29e-95	yckC	-	-	S	-	-	-	membrane
LEFFLKOP_03381	1.01e-68	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
LEFFLKOP_03382	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
LEFFLKOP_03383	4.78e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
LEFFLKOP_03384	3.23e-99	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
LEFFLKOP_03385	1.86e-268	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
LEFFLKOP_03386	1.13e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
LEFFLKOP_03387	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
LEFFLKOP_03388	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
LEFFLKOP_03389	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEFFLKOP_03390	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEFFLKOP_03391	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
LEFFLKOP_03392	1.63e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
LEFFLKOP_03393	4.41e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
LEFFLKOP_03394	1.17e-119	-	-	-	S	-	-	-	YcxB-like protein
LEFFLKOP_03395	3.27e-205	ycxC	-	-	EG	-	-	-	EamA-like transporter family
LEFFLKOP_03396	4.49e-313	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
LEFFLKOP_03397	2.02e-146	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
LEFFLKOP_03398	3.04e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
LEFFLKOP_03399	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
LEFFLKOP_03400	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
LEFFLKOP_03401	1.23e-187	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
LEFFLKOP_03402	5.32e-209	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
LEFFLKOP_03403	2.24e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LEFFLKOP_03404	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LEFFLKOP_03405	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
LEFFLKOP_03406	3.57e-108	yclD	-	-	-	-	-	-	-
LEFFLKOP_03407	9.51e-203	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
LEFFLKOP_03408	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
LEFFLKOP_03409	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
LEFFLKOP_03411	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
LEFFLKOP_03412	8.35e-297	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
LEFFLKOP_03413	2.29e-254	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
LEFFLKOP_03414	1.18e-155	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
LEFFLKOP_03415	5.59e-280	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
LEFFLKOP_03416	2.23e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEFFLKOP_03417	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LEFFLKOP_03418	7.71e-98	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
LEFFLKOP_03420	6.5e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
LEFFLKOP_03421	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
LEFFLKOP_03422	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEFFLKOP_03423	7.77e-210	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEFFLKOP_03424	1.61e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_03425	3.09e-217	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
LEFFLKOP_03426	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
LEFFLKOP_03427	5.87e-198	ycnC	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_03428	2.48e-173	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
LEFFLKOP_03429	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
LEFFLKOP_03430	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
LEFFLKOP_03431	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEFFLKOP_03432	4.64e-311	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEFFLKOP_03433	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEFFLKOP_03434	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
LEFFLKOP_03435	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEFFLKOP_03436	3.99e-134	ycnI	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_03437	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
LEFFLKOP_03438	1.22e-137	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
LEFFLKOP_03439	1.34e-74	-	-	-	-	-	-	-	-
LEFFLKOP_03440	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
LEFFLKOP_03441	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LEFFLKOP_03442	5.13e-267	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
LEFFLKOP_03443	3.96e-254	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
LEFFLKOP_03445	1.78e-96	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
LEFFLKOP_03446	1.71e-143	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
LEFFLKOP_03447	1.89e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
LEFFLKOP_03449	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
LEFFLKOP_03450	3.82e-181	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
LEFFLKOP_03451	1.87e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
LEFFLKOP_03452	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
LEFFLKOP_03453	9.77e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
LEFFLKOP_03454	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
LEFFLKOP_03455	1.55e-170	kipR	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_03456	5.94e-154	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
LEFFLKOP_03458	8.97e-65	yczJ	-	-	S	-	-	-	biosynthesis
LEFFLKOP_03459	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
LEFFLKOP_03460	8.6e-220	ycsN	-	-	S	-	-	-	Oxidoreductase
LEFFLKOP_03461	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
LEFFLKOP_03462	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
LEFFLKOP_03463	6.05e-129	ydaC	-	-	Q	-	-	-	Methyltransferase domain
LEFFLKOP_03464	3.74e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEFFLKOP_03465	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
LEFFLKOP_03466	6.6e-134	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LEFFLKOP_03467	5.24e-101	ydaG	-	-	S	-	-	-	general stress protein
LEFFLKOP_03468	1.31e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LEFFLKOP_03469	1.88e-62	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
LEFFLKOP_03470	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
LEFFLKOP_03471	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEFFLKOP_03472	2.96e-265	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LEFFLKOP_03473	3.01e-191	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
LEFFLKOP_03474	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
LEFFLKOP_03475	1.61e-219	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
LEFFLKOP_03476	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
LEFFLKOP_03477	0.0	ydaO	-	-	E	-	-	-	amino acid
LEFFLKOP_03478	3.08e-102	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
LEFFLKOP_03479	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
LEFFLKOP_03480	2.14e-53	-	-	-	-	-	-	-	-
LEFFLKOP_03481	3.9e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
LEFFLKOP_03482	1.67e-42	ydaS	-	-	S	-	-	-	membrane
LEFFLKOP_03483	2.25e-100	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
LEFFLKOP_03484	1.06e-190	ydbA	-	-	P	-	-	-	EcsC protein family
LEFFLKOP_03485	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
LEFFLKOP_03486	7.58e-79	ydbB	-	-	G	-	-	-	Cupin domain
LEFFLKOP_03487	5.41e-84	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
LEFFLKOP_03488	3.87e-198	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
LEFFLKOP_03489	1.43e-250	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LEFFLKOP_03490	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
LEFFLKOP_03491	1.38e-154	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
LEFFLKOP_03492	8.93e-290	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEFFLKOP_03493	1.32e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
LEFFLKOP_03494	3.23e-219	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_03495	2.99e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LEFFLKOP_03496	9.32e-70	ydbL	-	-	-	-	-	-	-
LEFFLKOP_03497	7.45e-280	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
LEFFLKOP_03498	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
LEFFLKOP_03500	1.35e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEFFLKOP_03501	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
LEFFLKOP_03502	3.58e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
LEFFLKOP_03503	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LEFFLKOP_03504	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LEFFLKOP_03505	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
LEFFLKOP_03506	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
LEFFLKOP_03507	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
LEFFLKOP_03508	1.6e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LEFFLKOP_03509	1.9e-233	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
LEFFLKOP_03510	1.39e-279	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEFFLKOP_03511	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LEFFLKOP_03512	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
LEFFLKOP_03513	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
LEFFLKOP_03514	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
LEFFLKOP_03515	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LEFFLKOP_03516	1.31e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
LEFFLKOP_03517	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
LEFFLKOP_03518	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LEFFLKOP_03519	3.12e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEFFLKOP_03520	7.57e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
LEFFLKOP_03521	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
LEFFLKOP_03522	2.17e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
LEFFLKOP_03530	7.32e-92	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
LEFFLKOP_03531	2.85e-58	-	-	-	-	-	-	-	-
LEFFLKOP_03532	3.85e-24	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	LXG domain of WXG superfamily
LEFFLKOP_03533	8.43e-29	-	-	-	L	ko:K07451,ko:K07452	-	ko00000,ko01000,ko02048	HNH endonuclease
LEFFLKOP_03534	9.05e-56	-	-	-	L	-	-	-	HNH nucleases
LEFFLKOP_03538	7.24e-08	-	-	-	S	-	-	-	Putative amidase domain
LEFFLKOP_03541	1.54e-46	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
LEFFLKOP_03542	6e-53	-	-	-	-	-	-	-	-
LEFFLKOP_03546	4.24e-146	ydeA	-	-	S	-	-	-	DJ-1/PfpI family
LEFFLKOP_03547	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
LEFFLKOP_03548	5.92e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
LEFFLKOP_03549	3.56e-184	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LEFFLKOP_03550	2.18e-213	-	-	-	K	-	-	-	AraC-like ligand binding domain
LEFFLKOP_03551	2.37e-222	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LEFFLKOP_03552	4.06e-209	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
LEFFLKOP_03553	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEFFLKOP_03554	3.8e-277	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
LEFFLKOP_03555	9.2e-70	ydeH	-	-	-	-	-	-	-
LEFFLKOP_03556	6.99e-136	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
LEFFLKOP_03557	2.46e-140	-	-	-	-	-	-	-	-
LEFFLKOP_03558	7.98e-100	-	-	-	I	-	-	-	Ribosomal RNA adenine dimethylase
LEFFLKOP_03559	5.54e-146	-	-	-	T	-	-	-	Transcriptional regulator
LEFFLKOP_03560	2.65e-176	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
LEFFLKOP_03561	6.97e-93	-	-	-	S	-	-	-	SNARE associated Golgi protein
LEFFLKOP_03563	2.7e-18	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
LEFFLKOP_03564	4.22e-111	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
LEFFLKOP_03565	1.82e-194	ydeK	-	-	EG	-	-	-	-transporter
LEFFLKOP_03566	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEFFLKOP_03567	3.68e-97	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
LEFFLKOP_03568	7.07e-137	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
LEFFLKOP_03569	5.22e-75	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
LEFFLKOP_03570	9.73e-196	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
LEFFLKOP_03571	1.02e-259	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
LEFFLKOP_03572	3.74e-136	ydeS	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_03573	2.56e-76	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
LEFFLKOP_03574	9.07e-297	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LEFFLKOP_03575	1.28e-187	-	-	-	J	-	-	-	GNAT acetyltransferase
LEFFLKOP_03576	1.69e-204	-	-	-	EG	-	-	-	EamA-like transporter family
LEFFLKOP_03577	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEFFLKOP_03578	2.84e-149	ydfE	-	-	S	-	-	-	Flavin reductase like domain
LEFFLKOP_03579	2.13e-158	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
LEFFLKOP_03580	3.77e-102	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LEFFLKOP_03582	3.37e-252	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_03583	9.37e-142	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEFFLKOP_03584	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
LEFFLKOP_03586	3e-220	-	-	-	S	-	-	-	Alpha/beta hydrolase family
LEFFLKOP_03587	3.77e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
LEFFLKOP_03588	1.18e-186	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
LEFFLKOP_03589	5.22e-199	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEFFLKOP_03590	2.83e-144	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
LEFFLKOP_03591	1.11e-237	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
LEFFLKOP_03592	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
LEFFLKOP_03593	2.19e-73	ydfQ	-	-	CO	-	-	-	Thioredoxin
LEFFLKOP_03594	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
LEFFLKOP_03595	5.33e-39	-	-	-	-	-	-	-	-
LEFFLKOP_03597	6.08e-153	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
LEFFLKOP_03598	4.44e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
LEFFLKOP_03599	3.13e-99	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
LEFFLKOP_03600	2.74e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
LEFFLKOP_03601	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
LEFFLKOP_03602	3.71e-122	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEFFLKOP_03603	5.53e-68	-	-	-	S	-	-	-	DoxX-like family
LEFFLKOP_03604	9.78e-112	yycN	-	-	K	-	-	-	Acetyltransferase
LEFFLKOP_03605	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
LEFFLKOP_03606	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
LEFFLKOP_03607	5.94e-118	-	-	-	S	-	-	-	DinB family
LEFFLKOP_03608	2.06e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
LEFFLKOP_03609	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
LEFFLKOP_03610	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
LEFFLKOP_03611	3.29e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
LEFFLKOP_03612	4.02e-265	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
LEFFLKOP_03613	1.77e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
LEFFLKOP_03614	7.15e-156	ydhC	-	-	K	-	-	-	FCD
LEFFLKOP_03615	4.24e-308	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
LEFFLKOP_03616	3.91e-289	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LEFFLKOP_03617	6.81e-160	-	-	-	-	-	-	-	-
LEFFLKOP_03618	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
LEFFLKOP_03619	2.74e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
LEFFLKOP_03621	2.2e-107	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
LEFFLKOP_03622	9.03e-230	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
LEFFLKOP_03623	7.76e-128	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
LEFFLKOP_03624	6.3e-255	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
LEFFLKOP_03625	7.97e-65	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFFLKOP_03626	1.44e-68	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFFLKOP_03627	2.27e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEFFLKOP_03628	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
LEFFLKOP_03629	7.75e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
LEFFLKOP_03630	7.02e-214	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
LEFFLKOP_03631	5.09e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
LEFFLKOP_03632	2.02e-272	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
LEFFLKOP_03633	4.89e-202	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
LEFFLKOP_03635	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
LEFFLKOP_03636	5.46e-74	ygzB	-	-	S	-	-	-	UPF0295 protein
LEFFLKOP_03637	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
LEFFLKOP_03638	1.19e-112	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
LEFFLKOP_03639	5.64e-313	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
LEFFLKOP_03640	1.87e-238	ygaE	-	-	S	-	-	-	Membrane
LEFFLKOP_03641	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
LEFFLKOP_03642	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
LEFFLKOP_03643	2.01e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
LEFFLKOP_03644	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
LEFFLKOP_03645	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEFFLKOP_03646	1.73e-48	yfhS	-	-	-	-	-	-	-
LEFFLKOP_03647	5.31e-265	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
LEFFLKOP_03648	7.22e-237	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
LEFFLKOP_03649	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
LEFFLKOP_03650	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
LEFFLKOP_03651	3.93e-218	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
LEFFLKOP_03652	4.74e-62	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
LEFFLKOP_03653	1.7e-117	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
LEFFLKOP_03654	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
LEFFLKOP_03655	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
LEFFLKOP_03656	3.47e-268	yfhI	-	-	EGP	-	-	-	-transporter
LEFFLKOP_03657	4.8e-67	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
LEFFLKOP_03658	9.32e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
LEFFLKOP_03659	3.11e-219	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
LEFFLKOP_03661	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
LEFFLKOP_03662	2.87e-138	yfhC	-	-	C	-	-	-	nitroreductase
LEFFLKOP_03663	7.61e-215	yfhB	-	-	S	-	-	-	PhzF family
LEFFLKOP_03664	7.36e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEFFLKOP_03665	8.91e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEFFLKOP_03666	1.56e-230	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
LEFFLKOP_03667	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEFFLKOP_03668	2.11e-103	yfiV	-	-	K	-	-	-	transcriptional
LEFFLKOP_03669	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
LEFFLKOP_03670	8.07e-128	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
LEFFLKOP_03671	5.4e-252	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LEFFLKOP_03672	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LEFFLKOP_03673	1.89e-128	padR	-	-	K	-	-	-	transcriptional
LEFFLKOP_03674	4.56e-267	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
LEFFLKOP_03675	3.66e-274	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
LEFFLKOP_03676	3.35e-218	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
LEFFLKOP_03677	1.05e-146	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
LEFFLKOP_03678	7.54e-276	baeS	-	-	T	-	-	-	Histidine kinase
LEFFLKOP_03680	5.17e-295	-	-	-	S	-	-	-	Oxidoreductase
LEFFLKOP_03681	5.47e-234	-	-	-	G	-	-	-	Xylose isomerase
LEFFLKOP_03682	0.0	yfiG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEFFLKOP_03683	1.28e-228	-	-	-	K	ko:K02099	-	ko00000,ko03000	AraC-like ligand binding domain
LEFFLKOP_03684	7.28e-209	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
LEFFLKOP_03685	2.01e-84	yfiD3	-	-	S	-	-	-	DoxX
LEFFLKOP_03686	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
LEFFLKOP_03687	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
LEFFLKOP_03688	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFFLKOP_03689	7.45e-182	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
LEFFLKOP_03690	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LEFFLKOP_03691	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
LEFFLKOP_03692	1.94e-270	yfjB	-	-	-	-	-	-	-
LEFFLKOP_03693	2.5e-185	yfjC	-	-	-	-	-	-	-
LEFFLKOP_03694	1.49e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
LEFFLKOP_03695	1.53e-104	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
LEFFLKOP_03696	7.42e-75	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
LEFFLKOP_03697	8.16e-36	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
LEFFLKOP_03698	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
LEFFLKOP_03699	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEFFLKOP_03700	4.19e-265	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEFFLKOP_03701	2.75e-244	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEFFLKOP_03702	1.36e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEFFLKOP_03703	7.85e-110	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
LEFFLKOP_03704	9.53e-241	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEFFLKOP_03705	3.04e-59	-	-	-	S	-	-	-	YfzA-like protein
LEFFLKOP_03706	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEFFLKOP_03707	2.76e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LEFFLKOP_03708	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
LEFFLKOP_03709	1.8e-189	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LEFFLKOP_03710	4.19e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
LEFFLKOP_03711	3.26e-36	yfjT	-	-	-	-	-	-	-
LEFFLKOP_03712	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
LEFFLKOP_03713	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
LEFFLKOP_03714	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
LEFFLKOP_03715	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
LEFFLKOP_03716	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_03717	1.64e-12	-	-	-	-	-	-	-	-
LEFFLKOP_03718	2.27e-182	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
LEFFLKOP_03719	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
LEFFLKOP_03720	9.78e-107	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEFFLKOP_03721	7.27e-42	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
LEFFLKOP_03722	7.24e-265	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_03723	5.48e-114	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
LEFFLKOP_03724	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
LEFFLKOP_03725	6.16e-160	frp	-	-	C	-	-	-	nitroreductase
LEFFLKOP_03726	1.45e-171	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
LEFFLKOP_03727	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
LEFFLKOP_03728	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
LEFFLKOP_03729	0.0	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
LEFFLKOP_03730	2.66e-270	yfkR	-	-	S	ko:K06297,ko:K06308	-	ko00000	spore germination
LEFFLKOP_03732	1.42e-245	yfkT	-	-	E	ko:K06309	-	ko00000	Spore germination protein
LEFFLKOP_03733	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
LEFFLKOP_03734	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
LEFFLKOP_03735	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
LEFFLKOP_03736	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LEFFLKOP_03737	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
LEFFLKOP_03738	2.1e-65	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
LEFFLKOP_03739	2.82e-26	yflI	-	-	-	-	-	-	-
LEFFLKOP_03740	1.1e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
LEFFLKOP_03741	5.68e-156	yflK	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_03742	2.97e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
LEFFLKOP_03743	1.67e-276	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LEFFLKOP_03744	8.08e-191	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
LEFFLKOP_03745	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
LEFFLKOP_03746	1.14e-229	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
LEFFLKOP_03747	1.88e-152	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
LEFFLKOP_03748	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
LEFFLKOP_03749	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
LEFFLKOP_03750	1.42e-306	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
LEFFLKOP_03751	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
LEFFLKOP_03752	4.91e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
LEFFLKOP_03753	2.88e-221	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LEFFLKOP_03754	1.92e-219	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEFFLKOP_03755	2.1e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEFFLKOP_03756	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
LEFFLKOP_03757	0.0	pkn1	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
LEFFLKOP_03758	1.72e-268	-	-	-	G	-	-	-	Major Facilitator Superfamily
LEFFLKOP_03759	6.98e-241	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
LEFFLKOP_03760	2.55e-105	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
LEFFLKOP_03761	1.2e-262	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
LEFFLKOP_03762	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LEFFLKOP_03763	7.24e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
LEFFLKOP_03764	3.03e-91	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
LEFFLKOP_03765	6.48e-99	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
LEFFLKOP_03766	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LEFFLKOP_03767	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
LEFFLKOP_03768	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEFFLKOP_03769	4.85e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
LEFFLKOP_03770	9.43e-171	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
LEFFLKOP_03771	3.59e-267	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
LEFFLKOP_03772	2.84e-244	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
LEFFLKOP_03773	2.44e-286	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
LEFFLKOP_03774	3.99e-231	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
LEFFLKOP_03775	9.86e-237	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
LEFFLKOP_03776	2.41e-187	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
LEFFLKOP_03777	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
LEFFLKOP_03778	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
LEFFLKOP_03779	4.11e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
LEFFLKOP_03780	1.78e-265	yetM	-	-	CH	-	-	-	FAD binding domain
LEFFLKOP_03781	2.75e-116	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
LEFFLKOP_03782	2.55e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
LEFFLKOP_03783	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
LEFFLKOP_03784	3.59e-184	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEFFLKOP_03785	9.79e-45	-	-	-	-	-	-	-	-
LEFFLKOP_03786	7.08e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEFFLKOP_03787	4.67e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
LEFFLKOP_03788	1.49e-156	yetF	-	-	S	-	-	-	membrane
LEFFLKOP_03789	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
LEFFLKOP_03790	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
LEFFLKOP_03791	1.01e-227	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
LEFFLKOP_03792	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
LEFFLKOP_03793	0.0	yetA	-	-	-	-	-	-	-
LEFFLKOP_03794	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
LEFFLKOP_03795	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
LEFFLKOP_03796	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
LEFFLKOP_03797	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
LEFFLKOP_03798	7.78e-143	-	-	-	S	-	-	-	Protein of unknown function, DUF624
LEFFLKOP_03799	7.22e-163	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
LEFFLKOP_03800	9.8e-169	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
LEFFLKOP_03801	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_03802	3.26e-253	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
LEFFLKOP_03803	2.96e-209	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
LEFFLKOP_03804	2.02e-218	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
LEFFLKOP_03805	2.39e-313	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
LEFFLKOP_03806	2.31e-256	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
LEFFLKOP_03807	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
LEFFLKOP_03808	5.16e-132	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
LEFFLKOP_03809	2.4e-130	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
LEFFLKOP_03810	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
LEFFLKOP_03811	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
LEFFLKOP_03812	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
LEFFLKOP_03813	8.28e-194	yesF	-	-	GM	-	-	-	NAD(P)H-binding
LEFFLKOP_03814	1.54e-101	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
LEFFLKOP_03815	4.04e-129	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
LEFFLKOP_03817	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
LEFFLKOP_03819	7.89e-268	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
LEFFLKOP_03820	4.24e-14	-	-	-	S	-	-	-	Pfam:DUF1311
LEFFLKOP_03821	1.4e-126	-	-	-	L	-	-	-	endonuclease activity
LEFFLKOP_03823	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
LEFFLKOP_03824	4.98e-107	-	-	-	S	-	-	-	Protein of unknown function, DUF600
LEFFLKOP_03826	1.02e-42	-	-	-	-	-	-	-	-
LEFFLKOP_03827	3.02e-68	-	-	-	S	-	-	-	37-kD nucleoid-associated bacterial protein
LEFFLKOP_03828	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEFFLKOP_03829	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LEFFLKOP_03830	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LEFFLKOP_03831	1.47e-190	yerO	-	-	K	-	-	-	Transcriptional regulator
LEFFLKOP_03832	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEFFLKOP_03833	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LEFFLKOP_03834	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEFFLKOP_03835	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEFFLKOP_03836	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
LEFFLKOP_03837	2.1e-251	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
LEFFLKOP_03838	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
LEFFLKOP_03839	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LEFFLKOP_03840	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
LEFFLKOP_03841	9.04e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LEFFLKOP_03843	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
LEFFLKOP_03844	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_03845	7.03e-246	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
LEFFLKOP_03846	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
LEFFLKOP_03847	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
LEFFLKOP_03848	9.05e-296	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
LEFFLKOP_03849	2.51e-94	-	-	-	K	-	-	-	helix_turn_helix ASNC type
LEFFLKOP_03850	3.29e-297	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
LEFFLKOP_03851	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
LEFFLKOP_03852	8.88e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LEFFLKOP_03853	1.71e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
LEFFLKOP_03854	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LEFFLKOP_03855	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEFFLKOP_03856	4.69e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEFFLKOP_03857	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEFFLKOP_03858	2.04e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
LEFFLKOP_03859	6.85e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LEFFLKOP_03860	3.55e-276	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LEFFLKOP_03861	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LEFFLKOP_03862	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
LEFFLKOP_03863	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
LEFFLKOP_03865	1.95e-163	yebC	-	-	M	-	-	-	Membrane
LEFFLKOP_03866	3.99e-282	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
LEFFLKOP_03867	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
LEFFLKOP_03868	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
LEFFLKOP_03869	3.2e-285	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LEFFLKOP_03870	2.79e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
LEFFLKOP_03871	6.13e-199	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEFFLKOP_03872	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
LEFFLKOP_03873	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
LEFFLKOP_03874	2.66e-224	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
LEFFLKOP_03875	2.08e-201	-	-	-	I	-	-	-	Alpha/beta hydrolase family
LEFFLKOP_03876	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
LEFFLKOP_03878	2.07e-210	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
LEFFLKOP_03879	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
LEFFLKOP_03880	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
LEFFLKOP_03881	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LEFFLKOP_03882	1.79e-244	-	-	-	S	-	-	-	Ion transport 2 domain protein
LEFFLKOP_03883	3.61e-203	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
LEFFLKOP_03884	2.2e-174	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
LEFFLKOP_03885	1.04e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEFFLKOP_03886	2.65e-146	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
LEFFLKOP_03887	1.42e-219	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
LEFFLKOP_03888	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
LEFFLKOP_03889	1.19e-255	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
LEFFLKOP_03890	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
LEFFLKOP_03891	1.55e-192	ydjC	-	-	S	-	-	-	Abhydrolase domain containing 18
LEFFLKOP_03892	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LEFFLKOP_03893	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LEFFLKOP_03894	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
LEFFLKOP_03895	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
LEFFLKOP_03896	8.73e-162	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LEFFLKOP_03897	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LEFFLKOP_03898	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LEFFLKOP_03899	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LEFFLKOP_03900	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
LEFFLKOP_03901	1.34e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LEFFLKOP_03902	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LEFFLKOP_03903	1.76e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
LEFFLKOP_03904	7.42e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
LEFFLKOP_03905	1.9e-231	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LEFFLKOP_03906	4.13e-179	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
LEFFLKOP_03907	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
LEFFLKOP_03908	3.49e-121	gerD	-	-	-	ko:K06294	-	ko00000	-
LEFFLKOP_03909	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LEFFLKOP_03910	9.05e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
LEFFLKOP_03911	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
LEFFLKOP_03912	1.24e-185	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
LEFFLKOP_03913	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
LEFFLKOP_03914	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LEFFLKOP_03915	1.51e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LEFFLKOP_03916	3.23e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEFFLKOP_03917	4.47e-196	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEFFLKOP_03918	7.5e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEFFLKOP_03919	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
LEFFLKOP_03920	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEFFLKOP_03921	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LEFFLKOP_03922	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LEFFLKOP_03923	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
LEFFLKOP_03924	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LEFFLKOP_03925	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
LEFFLKOP_03926	1.46e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LEFFLKOP_03927	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LEFFLKOP_03928	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
LEFFLKOP_03929	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
LEFFLKOP_03930	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LEFFLKOP_03931	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LEFFLKOP_03932	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LEFFLKOP_03933	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LEFFLKOP_03934	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEFFLKOP_03935	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LEFFLKOP_03936	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LEFFLKOP_03937	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LEFFLKOP_03938	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LEFFLKOP_03939	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
LEFFLKOP_03940	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LEFFLKOP_03941	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LEFFLKOP_03942	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LEFFLKOP_03943	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LEFFLKOP_03944	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LEFFLKOP_03945	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LEFFLKOP_03946	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
LEFFLKOP_03947	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LEFFLKOP_03948	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
LEFFLKOP_03949	2.04e-227	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
LEFFLKOP_03950	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEFFLKOP_03951	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LEFFLKOP_03952	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LEFFLKOP_03953	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LEFFLKOP_03954	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
LEFFLKOP_03955	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEFFLKOP_03956	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEFFLKOP_03957	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
LEFFLKOP_03958	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LEFFLKOP_03959	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LEFFLKOP_03960	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LEFFLKOP_03961	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LEFFLKOP_03962	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
LEFFLKOP_03963	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LEFFLKOP_03964	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
LEFFLKOP_03965	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
LEFFLKOP_03966	3.52e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEFFLKOP_03967	2.04e-95	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LEFFLKOP_03968	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
LEFFLKOP_03969	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
LEFFLKOP_03970	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEFFLKOP_03971	6.35e-113	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LEFFLKOP_03972	8.66e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LEFFLKOP_03973	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
LEFFLKOP_03974	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LEFFLKOP_03975	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LEFFLKOP_03976	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
LEFFLKOP_03977	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LEFFLKOP_03978	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
LEFFLKOP_03979	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
LEFFLKOP_03980	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
LEFFLKOP_03981	1.82e-130	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
LEFFLKOP_03982	8.37e-259	yaaN	-	-	P	-	-	-	Belongs to the TelA family
LEFFLKOP_03983	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
LEFFLKOP_03984	1.1e-144	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LEFFLKOP_03985	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_03986	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
LEFFLKOP_03987	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
LEFFLKOP_03988	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
LEFFLKOP_03989	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
LEFFLKOP_03990	3.28e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
LEFFLKOP_03991	1.2e-64	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
LEFFLKOP_03992	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LEFFLKOP_03993	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
LEFFLKOP_03994	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEFFLKOP_03995	5.05e-185	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
LEFFLKOP_03996	1.91e-283	yabE	-	-	T	-	-	-	protein conserved in bacteria
LEFFLKOP_03997	1.05e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LEFFLKOP_03998	1.24e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LEFFLKOP_03999	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
LEFFLKOP_04000	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
LEFFLKOP_04001	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
LEFFLKOP_04002	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LEFFLKOP_04003	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
LEFFLKOP_04004	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
LEFFLKOP_04005	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LEFFLKOP_04006	2.58e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LEFFLKOP_04007	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEFFLKOP_04008	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LEFFLKOP_04009	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LEFFLKOP_04010	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
LEFFLKOP_04011	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LEFFLKOP_04012	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
LEFFLKOP_04013	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEFFLKOP_04014	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LEFFLKOP_04015	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LEFFLKOP_04016	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
LEFFLKOP_04017	1.49e-137	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
LEFFLKOP_04018	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
LEFFLKOP_04019	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
LEFFLKOP_04022	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
LEFFLKOP_04023	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
LEFFLKOP_04024	8.42e-237	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
LEFFLKOP_04025	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LEFFLKOP_04026	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
LEFFLKOP_04027	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LEFFLKOP_04028	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LEFFLKOP_04029	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LEFFLKOP_04030	3.7e-193	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
LEFFLKOP_04031	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
LEFFLKOP_04032	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LEFFLKOP_04033	1.72e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
LEFFLKOP_04034	2.18e-214	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
LEFFLKOP_04035	7.82e-204	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LEFFLKOP_04036	6.31e-79	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LEFFLKOP_04037	4.56e-115	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LEFFLKOP_04038	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
LEFFLKOP_04039	1.59e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEFFLKOP_04040	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
LEFFLKOP_04041	1.51e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF3992)
LEFFLKOP_04042	4.35e-53	-	-	-	S	-	-	-	Spore coat protein Z
LEFFLKOP_04043	1.14e-117	-	-	-	S	-	-	-	Tetratricopeptide repeat
LEFFLKOP_04046	0.0	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
LEFFLKOP_04047	1.37e-135	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
LEFFLKOP_04049	5.4e-80	-	-	-	-	-	-	-	-
LEFFLKOP_04052	9.72e-187	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
LEFFLKOP_04053	8.36e-89	-	-	-	S	-	-	-	Bacteriophage holin family
LEFFLKOP_04054	2.45e-213	xepA	-	-	-	-	-	-	-
LEFFLKOP_04055	9.34e-33	-	-	-	-	-	-	-	-
LEFFLKOP_04056	1.01e-73	xkdW	-	-	S	-	-	-	XkdW protein
LEFFLKOP_04057	2.91e-283	-	-	-	-	-	-	-	-
LEFFLKOP_04058	3e-54	-	-	-	-	-	-	-	-
LEFFLKOP_04059	4.58e-134	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
LEFFLKOP_04060	1.31e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LEFFLKOP_04061	1.14e-91	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
LEFFLKOP_04062	6.68e-52	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
LEFFLKOP_04063	1.02e-231	xkdQ	-	-	G	-	-	-	NLP P60 protein
LEFFLKOP_04064	6.56e-156	xkdP	-	-	S	-	-	-	Lysin motif
LEFFLKOP_04065	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
LEFFLKOP_04066	9.14e-88	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
LEFFLKOP_04068	7.03e-98	xkdM	-	-	S	-	-	-	Phage tail tube protein
LEFFLKOP_04069	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
LEFFLKOP_04070	2.52e-36	-	-	-	-	-	-	-	-
LEFFLKOP_04071	1.48e-98	yqbJ	-	-	-	-	-	-	-
LEFFLKOP_04072	1.79e-112	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
LEFFLKOP_04073	9.68e-83	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
LEFFLKOP_04074	1.43e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3199)
LEFFLKOP_04075	2.12e-60	-	-	-	S	-	-	-	YqbF, hypothetical protein domain
LEFFLKOP_04076	8.83e-214	xkdG	-	-	S	-	-	-	Phage capsid family
LEFFLKOP_04077	4.23e-158	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
LEFFLKOP_04079	1.79e-194	-	-	-	S	-	-	-	Phage Mu protein F like protein
LEFFLKOP_04080	0.0	yqbA	-	-	S	-	-	-	portal protein
LEFFLKOP_04081	6.32e-311	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
LEFFLKOP_04082	7.73e-147	yqaS	-	-	L	-	-	-	DNA packaging
LEFFLKOP_04084	2.83e-99	yqaQ	-	-	L	-	-	-	Transposase
LEFFLKOP_04086	8.38e-42	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
LEFFLKOP_04087	1.28e-93	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
LEFFLKOP_04089	5.04e-207	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
LEFFLKOP_04090	5.29e-156	yqaL	-	-	L	-	-	-	DnaD domain protein
LEFFLKOP_04091	2.79e-192	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
LEFFLKOP_04092	3.18e-213	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
LEFFLKOP_04096	1.04e-133	-	-	-	-	-	-	-	-
LEFFLKOP_04098	3.43e-49	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
LEFFLKOP_04099	1.25e-74	-	-	-	K	-	-	-	sequence-specific DNA binding
LEFFLKOP_04101	8.73e-132	yqaC	-	-	F	-	-	-	adenylate kinase activity
LEFFLKOP_04102	1.58e-122	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
LEFFLKOP_04103	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
LEFFLKOP_04104	9.82e-101	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Catalyzes the reduction of arsenate As(V) to arsenite As(III)
LEFFLKOP_04105	7.13e-233	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Arsenic resistance protein
LEFFLKOP_04106	2.56e-104	cadI	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEFFLKOP_04107	1.53e-72	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	ArsR family transcriptional regulator
LEFFLKOP_04108	2.08e-197	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
LEFFLKOP_04109	1.37e-30	-	-	-	S	-	-	-	YtkA-like
LEFFLKOP_04110	9e-62	-	-	-	S	-	-	-	PepSY-associated TM region
LEFFLKOP_04111	3.91e-141	-	-	-	S	-	-	-	PepSY-associated TM region
LEFFLKOP_04112	3.16e-81	-	-	-	K	-	-	-	BetI-type transcriptional repressor, C-terminal
LEFFLKOP_04113	1.78e-175	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
LEFFLKOP_04114	1.21e-63	-	-	-	-	-	-	-	-