ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MILDBHCC_00001 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MILDBHCC_00002 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MILDBHCC_00003 5.41e-225 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
MILDBHCC_00004 3.31e-201 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, thiamine diphosphate binding domain
MILDBHCC_00005 2.72e-238 purR13 - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
MILDBHCC_00006 0.0 - - - G - - - isomerase
MILDBHCC_00007 0.0 - - - G - - - Protein of unknown function (DUF4038)
MILDBHCC_00008 1.57e-196 licT - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MILDBHCC_00009 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MILDBHCC_00010 8.2e-218 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MILDBHCC_00011 2.9e-215 - - - EGP - - - Transporter, major facilitator family protein
MILDBHCC_00012 0.0 - - - S - - - Domain of unknown function (DUF5060)
MILDBHCC_00013 5.07e-151 - - - C - - - nitroreductase
MILDBHCC_00014 6.92e-215 - - - C - - - Oxidoreductase
MILDBHCC_00015 6.56e-97 - - - S - - - SnoaL-like domain
MILDBHCC_00016 1.69e-13 - - - G - - - Ribose/Galactose Isomerase
MILDBHCC_00017 1.17e-116 - - - G - - - Ribose/Galactose Isomerase
MILDBHCC_00018 6.48e-267 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MILDBHCC_00020 3.08e-74 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MILDBHCC_00021 1.44e-98 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MILDBHCC_00022 1.4e-229 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
MILDBHCC_00023 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MILDBHCC_00024 1.74e-311 - 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MILDBHCC_00025 8.89e-269 - - - P - - - Major Facilitator Superfamily
MILDBHCC_00026 1.68e-109 yfhC - - C - - - nitroreductase
MILDBHCC_00027 4.91e-59 - - - V - - - ABC transporter transmembrane region
MILDBHCC_00028 3.17e-277 - - - V - - - ABC transporter transmembrane region
MILDBHCC_00029 3.25e-70 - - - - - - - -
MILDBHCC_00030 5.13e-80 - - - - - - - -
MILDBHCC_00031 1.11e-100 - - - K - - - Acetyltransferase (GNAT) domain
MILDBHCC_00032 9.86e-110 - - - FG - - - HIT domain
MILDBHCC_00033 8.86e-62 - - - S - - - MazG-like family
MILDBHCC_00034 7.67e-80 - - - - - - - -
MILDBHCC_00035 6.76e-152 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MILDBHCC_00036 2.56e-56 - - - - - - - -
MILDBHCC_00037 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MILDBHCC_00038 4.68e-182 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
MILDBHCC_00039 2.83e-121 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MILDBHCC_00040 2.99e-119 - 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 Acetyltransferase (GNAT) family
MILDBHCC_00041 2.26e-149 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MILDBHCC_00042 7.72e-181 - - - S - - - Alpha/beta hydrolase family
MILDBHCC_00043 4.96e-146 - - - - - - - -
MILDBHCC_00044 5.01e-106 - - - - - - - -
MILDBHCC_00045 4.7e-120 - - - S - - - AAA domain
MILDBHCC_00046 1.06e-195 - - - M - - - Phosphotransferase enzyme family
MILDBHCC_00047 4.33e-109 - - - F - - - NUDIX domain
MILDBHCC_00048 7.18e-07 - - - F - - - Phosphorylase superfamily
MILDBHCC_00049 2.72e-191 - - - F - - - Phosphorylase superfamily
MILDBHCC_00050 6.17e-193 - - - F - - - Phosphorylase superfamily
MILDBHCC_00051 8.85e-111 - - - S - - - ASCH
MILDBHCC_00052 9.13e-202 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MILDBHCC_00053 5.83e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MILDBHCC_00054 5.97e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
MILDBHCC_00055 5.51e-200 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
MILDBHCC_00056 7.29e-269 - - - G - - - Transmembrane secretion effector
MILDBHCC_00057 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MILDBHCC_00058 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MILDBHCC_00059 4.72e-240 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MILDBHCC_00060 4.33e-260 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MILDBHCC_00061 2.03e-224 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MILDBHCC_00062 4.95e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
MILDBHCC_00063 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MILDBHCC_00064 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MILDBHCC_00065 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MILDBHCC_00066 1.87e-115 ypmB - - S - - - Protein conserved in bacteria
MILDBHCC_00067 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MILDBHCC_00068 1.39e-148 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
MILDBHCC_00069 2.33e-149 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MILDBHCC_00070 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MILDBHCC_00071 5.29e-148 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MILDBHCC_00072 1.61e-136 ypsA - - S - - - Belongs to the UPF0398 family
MILDBHCC_00073 2.77e-94 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MILDBHCC_00074 3.8e-274 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MILDBHCC_00075 1.17e-309 cpdA - - S - - - Calcineurin-like phosphoesterase
MILDBHCC_00076 6.42e-287 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
MILDBHCC_00077 1.38e-224 degV1 - - S - - - DegV family
MILDBHCC_00078 1.53e-74 - - - - - - - -
MILDBHCC_00079 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MILDBHCC_00080 7.17e-99 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MILDBHCC_00081 4.78e-219 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MILDBHCC_00082 7.66e-251 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MILDBHCC_00083 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MILDBHCC_00084 0.0 FbpA - - K - - - Fibronectin-binding protein
MILDBHCC_00085 1.32e-84 - - - - - - - -
MILDBHCC_00086 5.52e-209 - - - S - - - EDD domain protein, DegV family
MILDBHCC_00087 4.79e-197 - - - - - - - -
MILDBHCC_00088 1.47e-212 lysR - - K - - - Transcriptional regulator
MILDBHCC_00089 9.84e-261 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
MILDBHCC_00090 1.62e-160 - - - S - - - Protein of unknown function (DUF1275)
MILDBHCC_00091 9.62e-142 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MILDBHCC_00092 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MILDBHCC_00093 4.97e-220 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MILDBHCC_00094 5.65e-229 - - - K - - - Transcriptional regulator
MILDBHCC_00095 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MILDBHCC_00096 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MILDBHCC_00097 1.62e-149 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MILDBHCC_00098 3.74e-148 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MILDBHCC_00099 4.22e-211 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MILDBHCC_00100 1.09e-141 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MILDBHCC_00101 2.17e-43 - - - - - - - -
MILDBHCC_00102 7.3e-216 - - - S ko:K07045 - ko00000 Amidohydrolase
MILDBHCC_00103 2.41e-298 - - - L ko:K07478 - ko00000 AAA C-terminal domain
MILDBHCC_00104 7.23e-25 lysR - - K - - - Transcriptional regulator
MILDBHCC_00105 5.72e-200 - - - C - - - Aldo keto reductase
MILDBHCC_00106 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MILDBHCC_00107 1.87e-92 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
MILDBHCC_00108 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
MILDBHCC_00109 3.65e-100 - - - S - - - Cupin domain
MILDBHCC_00110 6.03e-114 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MILDBHCC_00111 9.35e-74 - - - S - - - Antibiotic biosynthesis monooxygenase
MILDBHCC_00113 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
MILDBHCC_00114 1.38e-89 - - - S - - - PFAM Archaeal ATPase
MILDBHCC_00115 2.4e-43 - - - S - - - PFAM Archaeal ATPase
MILDBHCC_00116 3.2e-30 - - - S - - - PFAM Archaeal ATPase
MILDBHCC_00117 2.85e-197 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MILDBHCC_00118 0.000705 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
MILDBHCC_00119 2.71e-180 - - - H - - - Nodulation protein S (NodS)
MILDBHCC_00120 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MILDBHCC_00121 1.02e-71 yitW - - S - - - Iron-sulfur cluster assembly protein
MILDBHCC_00122 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MILDBHCC_00123 1.4e-104 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MILDBHCC_00124 3.7e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MILDBHCC_00125 6.53e-291 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
MILDBHCC_00126 4.3e-186 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MILDBHCC_00127 3.64e-312 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MILDBHCC_00128 6.71e-134 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
MILDBHCC_00129 2.71e-32 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MILDBHCC_00130 4.12e-156 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MILDBHCC_00131 4.05e-119 ykoJ - - S - - - Peptidase propeptide and YPEB domain
MILDBHCC_00132 5.05e-313 - - - T - - - GHKL domain
MILDBHCC_00133 5.04e-164 - - - T - - - Transcriptional regulatory protein, C terminal
MILDBHCC_00134 3.45e-150 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MILDBHCC_00135 6.22e-140 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
MILDBHCC_00136 1.56e-89 - - - S - - - reductase
MILDBHCC_00137 2.7e-139 ybbB - - S - - - Protein of unknown function (DUF1211)
MILDBHCC_00138 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
MILDBHCC_00139 6.13e-67 - - - D - - - Domain of Unknown Function (DUF1542)
MILDBHCC_00140 8.95e-95 - - - K - - - LytTr DNA-binding domain
MILDBHCC_00141 7.2e-84 - - - S - - - Protein of unknown function (DUF3021)
MILDBHCC_00142 4.14e-174 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MILDBHCC_00143 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MILDBHCC_00144 1.25e-107 - - - S - - - Pyridoxamine 5'-phosphate oxidase
MILDBHCC_00145 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
MILDBHCC_00146 8.58e-228 - - - S - - - Conserved hypothetical protein 698
MILDBHCC_00147 7.15e-94 - - - - - - - -
MILDBHCC_00149 5.82e-130 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MILDBHCC_00150 4.81e-124 - - - K - - - LysR substrate binding domain
MILDBHCC_00151 3.4e-228 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MILDBHCC_00152 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MILDBHCC_00153 1.9e-115 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MILDBHCC_00154 8.22e-217 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
MILDBHCC_00155 8.35e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MILDBHCC_00156 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MILDBHCC_00157 2.06e-197 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MILDBHCC_00158 2.57e-171 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MILDBHCC_00159 1.41e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MILDBHCC_00160 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MILDBHCC_00161 3.74e-48 yozE - - S - - - Belongs to the UPF0346 family
MILDBHCC_00162 1.05e-192 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
MILDBHCC_00163 2.78e-147 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MILDBHCC_00164 2.35e-287 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MILDBHCC_00165 4.7e-206 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MILDBHCC_00166 7.47e-76 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
MILDBHCC_00167 6.18e-183 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
MILDBHCC_00168 7.7e-156 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
MILDBHCC_00169 7.57e-67 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MILDBHCC_00170 1.11e-80 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
MILDBHCC_00171 7.12e-282 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MILDBHCC_00172 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MILDBHCC_00173 5.36e-296 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MILDBHCC_00174 1.37e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MILDBHCC_00175 1.5e-311 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MILDBHCC_00176 6.93e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MILDBHCC_00177 1.78e-152 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MILDBHCC_00178 1.1e-123 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MILDBHCC_00179 1.93e-106 - - - M - - - Lysin motif
MILDBHCC_00180 3.96e-165 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MILDBHCC_00181 4.56e-136 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MILDBHCC_00182 2.38e-170 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MILDBHCC_00183 1.95e-82 ribT - - K ko:K02859 - ko00000 acetyltransferase
MILDBHCC_00184 5.56e-214 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MILDBHCC_00185 9.56e-211 yitL - - S ko:K00243 - ko00000 S1 domain
MILDBHCC_00186 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MILDBHCC_00187 2.8e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MILDBHCC_00188 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MILDBHCC_00189 7.45e-36 - - - S - - - Protein of unknown function (DUF2929)
MILDBHCC_00190 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MILDBHCC_00191 3.88e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MILDBHCC_00192 8.03e-63 - - - S - - - Lipopolysaccharide assembly protein A domain
MILDBHCC_00193 2.91e-184 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MILDBHCC_00194 1.14e-224 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MILDBHCC_00195 0.0 oatA - - I - - - Acyltransferase
MILDBHCC_00196 7.6e-306 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MILDBHCC_00197 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MILDBHCC_00198 2.03e-222 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
MILDBHCC_00199 8.71e-133 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
MILDBHCC_00200 1.35e-194 - - - L - - - Phage integrase, N-terminal SAM-like domain
MILDBHCC_00201 5.48e-150 - - - GM - - - NmrA-like family
MILDBHCC_00202 1.06e-314 yagE - - E - - - amino acid
MILDBHCC_00203 1.84e-210 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
MILDBHCC_00204 2.44e-148 - - - T - - - Region found in RelA / SpoT proteins
MILDBHCC_00205 1.75e-150 dltr - - K - - - response regulator
MILDBHCC_00206 3.85e-292 sptS - - T - - - Histidine kinase
MILDBHCC_00207 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MILDBHCC_00208 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MILDBHCC_00209 1.98e-187 - - - S - - - haloacid dehalogenase-like hydrolase
MILDBHCC_00211 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
MILDBHCC_00212 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MILDBHCC_00213 8.07e-91 - - - - - - - -
MILDBHCC_00214 8.04e-139 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
MILDBHCC_00215 1.98e-190 - - - M - - - Glycosyl transferase family 2
MILDBHCC_00216 2.88e-125 - - - S - - - Domain of unknown function (DUF4811)
MILDBHCC_00217 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MILDBHCC_00218 3.24e-102 - - - K - - - MerR HTH family regulatory protein
MILDBHCC_00219 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MILDBHCC_00220 2.46e-81 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
MILDBHCC_00221 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MILDBHCC_00224 1.67e-104 - - - M - - - Sortase family
MILDBHCC_00225 2.08e-13 - - - GK - - - ROK family
MILDBHCC_00226 5.65e-171 - - - GK - - - ROK family
MILDBHCC_00227 1.93e-81 - - - K - - - AraC-like ligand binding domain
MILDBHCC_00228 2.46e-74 - - - K - - - helix_turn_helix, arabinose operon control protein
MILDBHCC_00229 4.93e-167 - - - I - - - Carboxylesterase family
MILDBHCC_00230 6.12e-46 - - - I - - - Carboxylesterase family
MILDBHCC_00231 0.0 - - - S - - - Predicted membrane protein (DUF2207)
MILDBHCC_00232 6.43e-160 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MILDBHCC_00233 1.7e-110 - - - - - - - -
MILDBHCC_00234 1.23e-189 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MILDBHCC_00235 2.46e-121 - - - S - - - ECF-type riboflavin transporter, S component
MILDBHCC_00236 8.45e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MILDBHCC_00237 1.87e-84 - - - - - - - -
MILDBHCC_00238 1.17e-17 - - - - - - - -
MILDBHCC_00239 3.98e-271 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MILDBHCC_00240 2.81e-194 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MILDBHCC_00241 1.75e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MILDBHCC_00242 1.67e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MILDBHCC_00243 9.89e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MILDBHCC_00244 1.57e-259 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MILDBHCC_00245 1.73e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MILDBHCC_00246 7.32e-95 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MILDBHCC_00247 1e-88 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MILDBHCC_00248 2.29e-190 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MILDBHCC_00249 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MILDBHCC_00250 2.74e-46 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MILDBHCC_00251 4.89e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MILDBHCC_00252 1.03e-196 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MILDBHCC_00253 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MILDBHCC_00254 7.04e-63 - - - - - - - -
MILDBHCC_00255 3.6e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MILDBHCC_00256 3.3e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MILDBHCC_00257 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MILDBHCC_00258 4.41e-220 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MILDBHCC_00259 4.56e-303 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MILDBHCC_00260 3.69e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MILDBHCC_00261 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MILDBHCC_00262 2.16e-207 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MILDBHCC_00263 4.51e-155 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MILDBHCC_00264 9.07e-158 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MILDBHCC_00265 6.36e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MILDBHCC_00266 8.29e-75 yloU - - S - - - Asp23 family, cell envelope-related function
MILDBHCC_00267 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MILDBHCC_00268 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MILDBHCC_00269 3.54e-231 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MILDBHCC_00270 1.53e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MILDBHCC_00271 9.96e-244 oppD - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MILDBHCC_00272 8.34e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MILDBHCC_00273 3.25e-225 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MILDBHCC_00274 1.06e-206 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MILDBHCC_00275 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MILDBHCC_00276 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MILDBHCC_00277 1.83e-159 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MILDBHCC_00278 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MILDBHCC_00279 2.93e-273 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MILDBHCC_00280 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MILDBHCC_00281 3.48e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MILDBHCC_00282 1.99e-291 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MILDBHCC_00283 1.37e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MILDBHCC_00284 9.87e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MILDBHCC_00285 2.14e-174 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MILDBHCC_00286 2.61e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MILDBHCC_00287 2.63e-151 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MILDBHCC_00288 2.61e-96 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
MILDBHCC_00289 2.15e-151 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
MILDBHCC_00290 7.82e-147 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MILDBHCC_00291 1.7e-45 ynzC - - S - - - UPF0291 protein
MILDBHCC_00292 4.85e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
MILDBHCC_00293 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MILDBHCC_00294 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MILDBHCC_00295 5.39e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MILDBHCC_00296 9.56e-151 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MILDBHCC_00297 3.79e-250 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MILDBHCC_00298 7.4e-181 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MILDBHCC_00299 8.74e-236 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MILDBHCC_00300 1.01e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MILDBHCC_00301 2.02e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MILDBHCC_00302 2.81e-174 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MILDBHCC_00303 3.37e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MILDBHCC_00304 1.09e-293 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MILDBHCC_00305 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MILDBHCC_00306 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MILDBHCC_00307 3.4e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MILDBHCC_00308 2.72e-281 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MILDBHCC_00309 1.08e-62 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MILDBHCC_00310 1.32e-63 - - - J - - - ribosomal protein
MILDBHCC_00311 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MILDBHCC_00312 4.75e-80 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MILDBHCC_00313 1.04e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MILDBHCC_00314 1.5e-226 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MILDBHCC_00315 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
MILDBHCC_00316 4.87e-121 - - - S - - - GyrI-like small molecule binding domain
MILDBHCC_00317 1.13e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MILDBHCC_00318 2.27e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MILDBHCC_00319 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MILDBHCC_00320 1.73e-252 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MILDBHCC_00321 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MILDBHCC_00322 4.45e-157 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MILDBHCC_00323 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MILDBHCC_00324 5.93e-124 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MILDBHCC_00325 0.0 potE - - E - - - Amino Acid
MILDBHCC_00326 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MILDBHCC_00327 2.62e-239 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MILDBHCC_00328 1.21e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MILDBHCC_00329 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MILDBHCC_00330 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
MILDBHCC_00331 6.2e-204 lysR5 - - K - - - LysR substrate binding domain
MILDBHCC_00333 4.39e-133 - - - I - - - PAP2 superfamily
MILDBHCC_00334 2.48e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MILDBHCC_00335 2.94e-42 - - - S - - - Sugar efflux transporter for intercellular exchange
MILDBHCC_00336 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MILDBHCC_00337 3.21e-244 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MILDBHCC_00338 2e-64 - - - K - - - Helix-turn-helix domain
MILDBHCC_00339 1.71e-181 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MILDBHCC_00340 9.68e-94 - - - L - - - nuclease
MILDBHCC_00341 5.71e-201 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MILDBHCC_00342 2.07e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MILDBHCC_00343 8.98e-127 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MILDBHCC_00344 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MILDBHCC_00345 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MILDBHCC_00346 8.88e-217 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MILDBHCC_00347 0.0 - - - S - - - Putative threonine/serine exporter
MILDBHCC_00348 2.09e-243 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
MILDBHCC_00349 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MILDBHCC_00350 0.0 - - - S - - - Bacterial membrane protein, YfhO
MILDBHCC_00351 3.6e-112 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MILDBHCC_00352 4.09e-221 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MILDBHCC_00353 1.91e-85 - - - - - - - -
MILDBHCC_00354 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MILDBHCC_00355 8.26e-96 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MILDBHCC_00356 9.01e-314 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MILDBHCC_00357 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MILDBHCC_00358 3.88e-284 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MILDBHCC_00359 4.29e-101 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MILDBHCC_00360 8.29e-174 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MILDBHCC_00361 5.01e-12 - - - - - - - -
MILDBHCC_00362 6.02e-133 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MILDBHCC_00363 2.23e-202 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MILDBHCC_00364 7.17e-154 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MILDBHCC_00365 6.79e-193 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MILDBHCC_00366 2.53e-67 yitW - - S - - - Iron-sulfur cluster assembly protein
MILDBHCC_00367 3.44e-200 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MILDBHCC_00368 8.33e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MILDBHCC_00369 5.18e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MILDBHCC_00370 2.02e-221 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MILDBHCC_00371 6.87e-114 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MILDBHCC_00372 6.75e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MILDBHCC_00373 2.79e-175 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MILDBHCC_00374 9.03e-229 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MILDBHCC_00375 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MILDBHCC_00376 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MILDBHCC_00377 8.64e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MILDBHCC_00378 1.17e-178 - - - - - - - -
MILDBHCC_00379 4.37e-119 - - - - - - - -
MILDBHCC_00381 2.52e-263 - - - M - - - domain protein
MILDBHCC_00382 1.6e-212 - - - S - - - DNA/RNA non-specific endonuclease
MILDBHCC_00383 2.61e-186 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
MILDBHCC_00384 1.32e-196 - - - EG - - - EamA-like transporter family
MILDBHCC_00385 3.42e-88 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MILDBHCC_00386 0.0 - - - M - - - Rib/alpha-like repeat
MILDBHCC_00387 5.36e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MILDBHCC_00388 7.58e-210 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MILDBHCC_00389 4.41e-131 - - - E - - - GDSL-like Lipase/Acylhydrolase
MILDBHCC_00390 2.68e-154 - - - S - - - Peptidase_C39 like family
MILDBHCC_00391 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MILDBHCC_00392 4.34e-152 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
MILDBHCC_00394 0.0 - 3.6.3.8 - P ko:K01537 - ko00000,ko01000 ATPase, P-type (transporting), HAD superfamily, subfamily IC
MILDBHCC_00395 3.25e-185 - - - K - - - Helix-turn-helix domain, rpiR family
MILDBHCC_00396 2.81e-165 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MILDBHCC_00397 0.0 ptsG 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MILDBHCC_00398 8.32e-192 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MILDBHCC_00399 1.65e-69 - - - - - - - -
MILDBHCC_00400 1.32e-35 - - - - - - - -
MILDBHCC_00401 1.46e-160 gpm2 - - G - - - Phosphoglycerate mutase family
MILDBHCC_00402 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MILDBHCC_00403 2.68e-172 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_00404 0.0 - - - E - - - Amino Acid
MILDBHCC_00405 4.75e-157 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MILDBHCC_00406 3.6e-159 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
MILDBHCC_00407 7.67e-176 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MILDBHCC_00408 4.53e-95 - - - - - - - -
MILDBHCC_00410 8.32e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MILDBHCC_00411 1.55e-294 - - - S - - - Putative peptidoglycan binding domain
MILDBHCC_00412 5.33e-172 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MILDBHCC_00413 3.38e-128 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
MILDBHCC_00414 1.87e-58 - - - - - - - -
MILDBHCC_00415 0.0 - - - S - - - O-antigen ligase like membrane protein
MILDBHCC_00416 3.86e-143 - - - - - - - -
MILDBHCC_00417 1.35e-107 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
MILDBHCC_00418 5.64e-227 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MILDBHCC_00419 3.93e-104 - - - - - - - -
MILDBHCC_00420 7.58e-79 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
MILDBHCC_00421 1.05e-53 - - - - - - - -
MILDBHCC_00422 2.22e-103 - - - S - - - Threonine/Serine exporter, ThrE
MILDBHCC_00423 5.17e-176 - - - S - - - Putative threonine/serine exporter
MILDBHCC_00424 0.0 - - - S - - - ABC transporter
MILDBHCC_00425 2.71e-81 - - - - - - - -
MILDBHCC_00426 2.47e-53 - - - - - - - -
MILDBHCC_00427 1.59e-266 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MILDBHCC_00428 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MILDBHCC_00429 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MILDBHCC_00430 1.03e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MILDBHCC_00431 4.48e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MILDBHCC_00432 2.74e-211 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MILDBHCC_00433 1.07e-57 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MILDBHCC_00434 2.58e-181 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MILDBHCC_00435 0.0 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MILDBHCC_00436 1.68e-93 - - - S - - - YSIRK type signal peptide
MILDBHCC_00437 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MILDBHCC_00438 5.13e-214 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MILDBHCC_00439 1.38e-176 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MILDBHCC_00440 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
MILDBHCC_00441 2.34e-283 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MILDBHCC_00442 1.53e-212 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_00443 1.76e-182 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MILDBHCC_00444 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MILDBHCC_00445 1.12e-267 - - - T - - - His Kinase A (phosphoacceptor) domain
MILDBHCC_00446 2.39e-156 vanR - - K - - - response regulator
MILDBHCC_00447 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MILDBHCC_00448 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_00449 3.36e-185 - - - S - - - Protein of unknown function (DUF1129)
MILDBHCC_00450 1.89e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MILDBHCC_00451 1.23e-56 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MILDBHCC_00452 9.01e-198 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MILDBHCC_00453 1.43e-176 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MILDBHCC_00454 1.13e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MILDBHCC_00455 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MILDBHCC_00456 3.16e-125 cvpA - - S - - - Colicin V production protein
MILDBHCC_00457 9e-226 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MILDBHCC_00458 3.05e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MILDBHCC_00459 1.28e-255 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
MILDBHCC_00460 4.45e-128 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MILDBHCC_00461 2.22e-125 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
MILDBHCC_00462 5.92e-142 - - - K - - - WHG domain
MILDBHCC_00463 5.54e-50 - - - - - - - -
MILDBHCC_00464 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MILDBHCC_00465 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MILDBHCC_00466 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MILDBHCC_00467 2.83e-200 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MILDBHCC_00468 5.63e-154 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_00469 5.03e-235 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MILDBHCC_00470 1.91e-119 - - - K - - - Bacterial regulatory proteins, tetR family
MILDBHCC_00471 4.06e-145 - - - G - - - phosphoglycerate mutase
MILDBHCC_00472 5.95e-147 - - - G - - - Phosphoglycerate mutase family
MILDBHCC_00473 1.14e-178 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
MILDBHCC_00474 1.29e-181 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MILDBHCC_00475 9.32e-67 - - - - - - - -
MILDBHCC_00476 2.6e-165 - - - - - - - -
MILDBHCC_00477 2.16e-208 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MILDBHCC_00478 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MILDBHCC_00479 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
MILDBHCC_00480 2.14e-185 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MILDBHCC_00481 6.9e-197 - - - K - - - Helix-turn-helix domain, rpiR family
MILDBHCC_00482 8.83e-201 - - - C - - - Domain of unknown function (DUF4931)
MILDBHCC_00483 3.16e-93 aroD 1.1.1.25, 4.2.1.10 - E ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 3-dehydroquinate dehydratase activity
MILDBHCC_00484 4.69e-202 - - - - - - - -
MILDBHCC_00485 3.13e-99 - - - EGP - - - Major Facilitator Superfamily
MILDBHCC_00486 8.68e-178 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MILDBHCC_00487 2.06e-161 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MILDBHCC_00488 0.0 - - - V - - - ABC transporter transmembrane region
MILDBHCC_00489 6.71e-113 ymdB - - S - - - Macro domain protein
MILDBHCC_00490 1.81e-46 - - - - - - - -
MILDBHCC_00491 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MILDBHCC_00492 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MILDBHCC_00493 4.28e-177 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
MILDBHCC_00494 4.68e-187 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MILDBHCC_00495 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MILDBHCC_00496 1.99e-168 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MILDBHCC_00497 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
MILDBHCC_00498 2.61e-205 - - - EG - - - EamA-like transporter family
MILDBHCC_00499 7.01e-244 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MILDBHCC_00500 3.46e-303 - - - E - - - amino acid
MILDBHCC_00501 2.51e-178 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MILDBHCC_00502 2.21e-296 yifK - - E ko:K03293 - ko00000 Amino acid permease
MILDBHCC_00503 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
MILDBHCC_00504 8.6e-86 - - - S - - - Domain of unknown function (DUF956)
MILDBHCC_00505 1.73e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MILDBHCC_00506 1.23e-166 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MILDBHCC_00507 1.83e-232 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MILDBHCC_00509 1.62e-194 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MILDBHCC_00510 9.97e-188 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MILDBHCC_00511 9.54e-97 - - - K - - - LytTr DNA-binding domain
MILDBHCC_00512 3.27e-83 - - - S - - - Protein of unknown function (DUF3021)
MILDBHCC_00513 1.47e-111 - - - K - - - Acetyltransferase (GNAT) domain
MILDBHCC_00514 2.63e-73 ywnA - - K - - - Transcriptional regulator
MILDBHCC_00515 2.53e-123 - - - - - - - -
MILDBHCC_00516 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MILDBHCC_00517 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MILDBHCC_00518 2.49e-259 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MILDBHCC_00519 7.55e-53 - - - - - - - -
MILDBHCC_00520 9.97e-105 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
MILDBHCC_00521 4.04e-103 - - - - - - - -
MILDBHCC_00522 1.46e-42 ydeP - - K - - - Transcriptional regulator, HxlR family
MILDBHCC_00523 1.14e-99 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
MILDBHCC_00524 1.29e-181 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MILDBHCC_00525 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MILDBHCC_00526 2.03e-290 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MILDBHCC_00527 5.42e-229 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MILDBHCC_00528 3.67e-184 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MILDBHCC_00529 1.04e-172 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_00530 0.0 - - - E - - - amino acid
MILDBHCC_00531 8.98e-55 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MILDBHCC_00532 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MILDBHCC_00533 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MILDBHCC_00534 5.86e-79 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MILDBHCC_00535 2.57e-273 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MILDBHCC_00536 3.03e-158 - - - S - - - (CBS) domain
MILDBHCC_00537 1.14e-231 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MILDBHCC_00538 4.45e-133 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MILDBHCC_00539 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MILDBHCC_00540 3.62e-46 yabO - - J - - - S4 domain protein
MILDBHCC_00541 1.52e-77 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MILDBHCC_00542 4.65e-80 - - - J ko:K07571 - ko00000 S1 RNA binding domain
MILDBHCC_00543 3.44e-311 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MILDBHCC_00544 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MILDBHCC_00545 0.0 - - - S - - - membrane
MILDBHCC_00546 0.0 - - - S - - - membrane
MILDBHCC_00547 1.92e-207 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MILDBHCC_00548 3.21e-244 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MILDBHCC_00549 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MILDBHCC_00552 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MILDBHCC_00553 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MILDBHCC_00554 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MILDBHCC_00555 8.18e-141 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MILDBHCC_00556 3.6e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MILDBHCC_00557 8.05e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MILDBHCC_00558 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MILDBHCC_00559 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MILDBHCC_00560 8.75e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MILDBHCC_00561 1.57e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MILDBHCC_00562 7.29e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MILDBHCC_00563 1.99e-198 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MILDBHCC_00564 6.08e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MILDBHCC_00565 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MILDBHCC_00566 1.29e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MILDBHCC_00567 3e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MILDBHCC_00568 2.92e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MILDBHCC_00569 7.74e-56 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MILDBHCC_00570 6.02e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MILDBHCC_00571 1.18e-46 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MILDBHCC_00572 6.1e-124 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MILDBHCC_00573 1.73e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MILDBHCC_00574 9.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MILDBHCC_00575 1.76e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MILDBHCC_00576 1.09e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MILDBHCC_00577 9.33e-107 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MILDBHCC_00578 3.44e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MILDBHCC_00579 5.78e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MILDBHCC_00580 1.2e-299 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MILDBHCC_00581 4.87e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MILDBHCC_00582 4.46e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MILDBHCC_00583 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MILDBHCC_00584 1.92e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MILDBHCC_00585 4.46e-81 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MILDBHCC_00586 7.63e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MILDBHCC_00587 1.1e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MILDBHCC_00588 1.63e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MILDBHCC_00589 4.05e-208 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MILDBHCC_00590 7.09e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MILDBHCC_00591 1.29e-191 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MILDBHCC_00592 1.08e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MILDBHCC_00593 1.13e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MILDBHCC_00595 2.8e-289 - - - P ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter
MILDBHCC_00596 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MILDBHCC_00597 5.89e-90 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
MILDBHCC_00598 1.88e-192 - - - GM - - - NmrA-like family
MILDBHCC_00599 4.42e-142 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MILDBHCC_00600 3.17e-166 - - - G - - - Belongs to the phosphoglycerate mutase family
MILDBHCC_00601 4.17e-67 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
MILDBHCC_00602 3.4e-198 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MILDBHCC_00603 9.99e-53 - - - - - - - -
MILDBHCC_00604 2.39e-16 - - - - - - - -
MILDBHCC_00605 7.96e-159 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MILDBHCC_00606 1.2e-236 - - - S - - - AAA domain
MILDBHCC_00607 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MILDBHCC_00608 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Contains amino acid permease domain
MILDBHCC_00609 2.28e-272 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
MILDBHCC_00610 0.0 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
MILDBHCC_00611 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
MILDBHCC_00612 3.04e-199 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
MILDBHCC_00613 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MILDBHCC_00614 0.0 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MILDBHCC_00615 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MILDBHCC_00616 1.22e-117 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MILDBHCC_00617 1.85e-284 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MILDBHCC_00618 1.26e-46 - - - S - - - Protein of unknown function (DUF2969)
MILDBHCC_00619 5.54e-69 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MILDBHCC_00620 3.34e-18 - - - S - - - DNA-directed RNA polymerase subunit beta
MILDBHCC_00621 3.53e-229 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MILDBHCC_00622 3.07e-42 - - - S - - - Protein of unknown function (DUF1146)
MILDBHCC_00623 6.02e-94 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MILDBHCC_00624 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MILDBHCC_00625 4.95e-219 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MILDBHCC_00626 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MILDBHCC_00627 1.13e-120 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MILDBHCC_00628 5.6e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MILDBHCC_00629 1.75e-35 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MILDBHCC_00630 7.4e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MILDBHCC_00631 2.61e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MILDBHCC_00632 8.5e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MILDBHCC_00633 5.31e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MILDBHCC_00634 4.43e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MILDBHCC_00635 8.2e-145 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MILDBHCC_00636 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
MILDBHCC_00637 4.58e-246 ampC - - V - - - Beta-lactamase
MILDBHCC_00640 1.31e-88 - - - - - - - -
MILDBHCC_00641 1.65e-309 - - - EGP - - - Major Facilitator
MILDBHCC_00642 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MILDBHCC_00643 1.52e-136 vanZ - - V - - - VanZ like family
MILDBHCC_00644 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MILDBHCC_00645 0.0 yclK - - T - - - Histidine kinase
MILDBHCC_00646 6.34e-165 - - - K - - - Transcriptional regulatory protein, C terminal
MILDBHCC_00647 4.63e-88 - - - S - - - SdpI/YhfL protein family
MILDBHCC_00648 3.75e-245 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MILDBHCC_00649 4.81e-77 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MILDBHCC_00650 4.05e-53 - - - S - - - Phage Mu protein F like protein
MILDBHCC_00651 2.98e-295 - - - S - - - Phage portal protein, SPP1 Gp6-like
MILDBHCC_00652 4.93e-309 yqaT - - S ko:K06909 - ko00000 Phage terminase, large subunit
MILDBHCC_00653 5e-84 - - - L ko:K07474 - ko00000 Terminase small subunit
MILDBHCC_00654 5.96e-37 - - - - - - - -
MILDBHCC_00658 5.12e-112 - - - - - - - -
MILDBHCC_00659 9.24e-27 - - - - - - - -
MILDBHCC_00660 7.58e-31 - - - - - - - -
MILDBHCC_00663 3.29e-54 - - - - - - - -
MILDBHCC_00664 1.59e-81 - - - L - - - Endodeoxyribonuclease RusA
MILDBHCC_00670 3.43e-35 - - - - - - - -
MILDBHCC_00671 1.89e-172 - - - S - - - DNA binding
MILDBHCC_00674 1.63e-23 ansR - - K - - - Transcriptional regulator
MILDBHCC_00675 5.42e-91 - - - L - - - Helix-turn-helix domain
MILDBHCC_00676 2.2e-55 - - - S - - - ERF superfamily
MILDBHCC_00678 4.47e-53 - - - - - - - -
MILDBHCC_00679 5.68e-22 - - - - - - - -
MILDBHCC_00681 1.32e-78 - - - S - - - Domain of unknown function (DUF771)
MILDBHCC_00683 7.15e-75 - - - S - - - protein disulfide oxidoreductase activity
MILDBHCC_00684 3.2e-109 - - - S - - - Pfam:Peptidase_M78
MILDBHCC_00685 4.4e-34 - - - S - - - Bacterial PH domain
MILDBHCC_00687 3.77e-189 int3 - - L - - - Belongs to the 'phage' integrase family
MILDBHCC_00688 3.42e-138 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MILDBHCC_00690 2.65e-43 - - - - - - - -
MILDBHCC_00691 2.44e-90 - - - - - - - -
MILDBHCC_00692 2.97e-50 - - - - - - - -
MILDBHCC_00694 0.0 - - - LM - - - gp58-like protein
MILDBHCC_00695 2.59e-68 - - - - - - - -
MILDBHCC_00696 0.0 - - - L - - - Phage tail tape measure protein TP901
MILDBHCC_00697 2.36e-61 - - - - - - - -
MILDBHCC_00698 2.95e-87 - - - - - - - -
MILDBHCC_00699 1.28e-100 - - - S - - - Phage tail tube protein, TTP
MILDBHCC_00700 7.61e-81 - - - - - - - -
MILDBHCC_00701 5e-124 - - - - - - - -
MILDBHCC_00702 2.32e-75 - - - - - - - -
MILDBHCC_00703 2.16e-60 - - - - - - - -
MILDBHCC_00704 1.16e-244 - - - S - - - Phage major capsid protein E
MILDBHCC_00705 1.18e-77 - - - - - - - -
MILDBHCC_00706 3.13e-95 - - - S - - - Domain of unknown function (DUF4355)
MILDBHCC_00708 9.08e-191 - - - S - - - Phage Mu protein F like protein
MILDBHCC_00709 4.58e-41 - - - S - - - Cysteine protease Prp
MILDBHCC_00710 5.83e-316 - - - S - - - Phage portal protein, SPP1 Gp6-like
MILDBHCC_00711 2.84e-315 - - - S - - - Terminase-like family
MILDBHCC_00712 2.21e-177 xtmA - - L ko:K07474 - ko00000 Terminase small subunit
MILDBHCC_00713 2.67e-112 - - - C - - - Domain of unknown function (DUF4145)
MILDBHCC_00715 1.26e-50 - - - S - - - VRR-NUC domain
MILDBHCC_00721 1.99e-236 - - - S ko:K06919 - ko00000 Virulence-associated protein E
MILDBHCC_00722 5.74e-130 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
MILDBHCC_00723 2.29e-34 - - - - - - - -
MILDBHCC_00724 3.78e-50 - - - - - - - -
MILDBHCC_00725 2.66e-141 - - - L - - - AAA domain
MILDBHCC_00727 3.06e-258 - - - L - - - Helicase C-terminal domain protein
MILDBHCC_00728 5.98e-07 - - - S - - - helicase activity
MILDBHCC_00730 6.02e-56 - - - S - - - Siphovirus Gp157
MILDBHCC_00732 5.84e-25 - - - - - - - -
MILDBHCC_00733 4.29e-40 - - - - - - - -
MILDBHCC_00735 8.4e-100 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
MILDBHCC_00736 4.8e-25 - - - K - - - Helix-turn-helix XRE-family like proteins
MILDBHCC_00737 1.64e-08 - - - K - - - Helix-turn-helix XRE-family like proteins
MILDBHCC_00740 3.76e-95 - - - S - - - Membrane
MILDBHCC_00741 9.92e-65 - - - M - - - Host cell surface-exposed lipoprotein
MILDBHCC_00742 3.87e-191 - - - L - - - Belongs to the 'phage' integrase family
MILDBHCC_00744 3.36e-289 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MILDBHCC_00745 9.87e-238 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MILDBHCC_00746 4.33e-109 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MILDBHCC_00748 5.63e-77 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
MILDBHCC_00749 9.23e-55 comGC - - U ko:K02245,ko:K02456 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 Required for transformation and DNA binding
MILDBHCC_00750 2.19e-225 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MILDBHCC_00751 5.45e-231 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MILDBHCC_00752 6.1e-171 yebC - - K - - - Transcriptional regulatory protein
MILDBHCC_00753 5.31e-125 - - - S - - - VanZ like family
MILDBHCC_00754 4.49e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MILDBHCC_00755 3.6e-210 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MILDBHCC_00756 5.08e-191 - - - S - - - Alpha/beta hydrolase family
MILDBHCC_00757 1.25e-150 - - - - - - - -
MILDBHCC_00758 6.31e-259 - - - S - - - Putative adhesin
MILDBHCC_00759 2.48e-80 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MILDBHCC_00760 3.02e-88 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MILDBHCC_00761 2.3e-189 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MILDBHCC_00762 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MILDBHCC_00763 4.25e-222 ybbR - - S - - - YbbR-like protein
MILDBHCC_00764 6.38e-197 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MILDBHCC_00765 4.21e-267 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MILDBHCC_00766 7.6e-176 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MILDBHCC_00767 1.45e-171 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MILDBHCC_00768 1.46e-261 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MILDBHCC_00769 1.07e-209 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MILDBHCC_00770 6.15e-127 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MILDBHCC_00771 2.91e-109 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MILDBHCC_00772 7.41e-229 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MILDBHCC_00773 1.02e-172 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MILDBHCC_00774 6.88e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MILDBHCC_00775 2.43e-121 - - - - - - - -
MILDBHCC_00776 1.09e-110 - - - - - - - -
MILDBHCC_00777 1.75e-166 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MILDBHCC_00778 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MILDBHCC_00779 0.0 yycH - - S - - - YycH protein
MILDBHCC_00780 1.49e-186 yycI - - S - - - YycH protein
MILDBHCC_00781 8.73e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MILDBHCC_00782 6.78e-236 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MILDBHCC_00783 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MILDBHCC_00784 1.09e-142 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MILDBHCC_00785 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_00786 5.59e-128 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MILDBHCC_00787 5.14e-216 - - - K - - - helix_turn_helix, arabinose operon control protein
MILDBHCC_00788 2.96e-209 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MILDBHCC_00789 2.67e-125 lemA - - S ko:K03744 - ko00000 LemA family
MILDBHCC_00790 4.27e-236 ysdE - - P - - - Citrate transporter
MILDBHCC_00791 7.84e-92 - - - S - - - Iron-sulphur cluster biosynthesis
MILDBHCC_00792 1.14e-23 - - - - - - - -
MILDBHCC_00793 5.1e-150 - - - - - - - -
MILDBHCC_00795 2.59e-312 - - - M - - - Glycosyl transferase
MILDBHCC_00796 4.96e-270 - - - G - - - Glycosyl hydrolases family 8
MILDBHCC_00797 1.11e-154 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MILDBHCC_00798 2.05e-227 - - - L - - - HNH nucleases
MILDBHCC_00799 5.01e-61 - - - - - - - -
MILDBHCC_00800 4.83e-177 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_00801 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MILDBHCC_00802 6.19e-149 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MILDBHCC_00803 4.1e-84 yeaO - - S - - - Protein of unknown function, DUF488
MILDBHCC_00804 2.41e-165 terC - - P - - - Integral membrane protein TerC family
MILDBHCC_00805 6.09e-113 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
MILDBHCC_00806 6.37e-170 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
MILDBHCC_00807 1.28e-103 - - - - - - - -
MILDBHCC_00808 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MILDBHCC_00809 5.18e-159 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
MILDBHCC_00810 7.39e-225 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MILDBHCC_00811 5.53e-180 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MILDBHCC_00813 2.02e-220 - - - S - - - Protein of unknown function (DUF1002)
MILDBHCC_00814 5.52e-204 epsV - - S - - - glycosyl transferase family 2
MILDBHCC_00815 3.44e-161 - - - S - - - Alpha/beta hydrolase family
MILDBHCC_00816 1.13e-81 - - - - - - - -
MILDBHCC_00817 6.1e-230 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MILDBHCC_00818 1.6e-305 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MILDBHCC_00819 1.01e-148 - - - K - - - Bacterial regulatory proteins, tetR family
MILDBHCC_00820 1.14e-161 - - - - - - - -
MILDBHCC_00821 0.0 - - - S - - - Cysteine-rich secretory protein family
MILDBHCC_00822 3.19e-264 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MILDBHCC_00823 1.06e-132 - - - - - - - -
MILDBHCC_00824 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
MILDBHCC_00825 4.73e-215 yibE - - S - - - overlaps another CDS with the same product name
MILDBHCC_00826 2.4e-157 yibF - - S - - - overlaps another CDS with the same product name
MILDBHCC_00827 2.55e-198 - - - I - - - alpha/beta hydrolase fold
MILDBHCC_00828 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
MILDBHCC_00829 2.69e-167 - - - K ko:K03710 - ko00000,ko03000 UTRA
MILDBHCC_00830 1.44e-276 agaS - - G ko:K02082 - ko00000,ko01000 SIS domain
MILDBHCC_00831 5.34e-291 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MILDBHCC_00832 9.66e-110 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MILDBHCC_00833 8.1e-191 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MILDBHCC_00834 1.02e-190 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MILDBHCC_00835 2.66e-88 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MILDBHCC_00836 5.08e-282 - - - S - - - zinc-ribbon domain
MILDBHCC_00837 1.56e-113 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
MILDBHCC_00838 1.76e-128 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MILDBHCC_00839 3.53e-169 - - - K - - - UTRA domain
MILDBHCC_00840 8.74e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MILDBHCC_00841 6.03e-114 usp5 - - T - - - universal stress protein
MILDBHCC_00843 1.16e-215 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
MILDBHCC_00844 1.28e-181 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MILDBHCC_00845 1.11e-169 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MILDBHCC_00846 6.11e-189 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MILDBHCC_00847 3.38e-109 - - - - - - - -
MILDBHCC_00848 0.0 - - - S - - - Calcineurin-like phosphoesterase
MILDBHCC_00849 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MILDBHCC_00850 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MILDBHCC_00851 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MILDBHCC_00852 1.51e-177 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MILDBHCC_00853 6.48e-136 yitW - - S - - - Iron-sulfur cluster assembly protein
MILDBHCC_00854 4.42e-292 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
MILDBHCC_00855 7.1e-291 yqjV - - EGP - - - Major Facilitator Superfamily
MILDBHCC_00856 2.95e-238 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
MILDBHCC_00857 0.0 - - - D - - - transport
MILDBHCC_00858 1.33e-174 rpl - - K - - - Helix-turn-helix domain, rpiR family
MILDBHCC_00859 7.3e-216 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MILDBHCC_00860 0.0 fruC 2.7.1.202 - GT ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MILDBHCC_00861 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MILDBHCC_00862 0.0 - - - S - - - Bacterial membrane protein, YfhO
MILDBHCC_00863 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MILDBHCC_00864 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MILDBHCC_00865 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MILDBHCC_00866 4.33e-95 - - - - - - - -
MILDBHCC_00867 5.83e-176 - - - - - - - -
MILDBHCC_00868 3.41e-37 - - - - - - - -
MILDBHCC_00869 3.38e-46 - - - S - - - Protein of unknown function (DUF2922)
MILDBHCC_00870 0.0 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MILDBHCC_00871 0.0 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MILDBHCC_00872 1.13e-184 - 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MILDBHCC_00873 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MILDBHCC_00874 1.01e-228 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MILDBHCC_00875 8.33e-182 - - - - - - - -
MILDBHCC_00876 3.27e-191 - - - - - - - -
MILDBHCC_00877 2.4e-97 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
MILDBHCC_00878 2.23e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MILDBHCC_00879 1.45e-60 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
MILDBHCC_00880 1.74e-181 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MILDBHCC_00881 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MILDBHCC_00882 2.28e-219 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MILDBHCC_00883 3.58e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MILDBHCC_00884 1.7e-146 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MILDBHCC_00885 2.51e-143 - - - S - - - CYTH
MILDBHCC_00886 5.4e-140 yjbH - - Q - - - Thioredoxin
MILDBHCC_00887 6e-212 coiA - - S ko:K06198 - ko00000 Competence protein
MILDBHCC_00888 1.15e-153 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MILDBHCC_00889 1.17e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MILDBHCC_00890 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MILDBHCC_00891 7.45e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MILDBHCC_00892 1.02e-34 - - - - - - - -
MILDBHCC_00893 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MILDBHCC_00894 2.17e-59 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
MILDBHCC_00895 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MILDBHCC_00896 5.48e-201 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
MILDBHCC_00897 9.83e-101 - - - - - - - -
MILDBHCC_00898 2.36e-116 - - - - - - - -
MILDBHCC_00899 2.33e-84 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MILDBHCC_00900 8.66e-32 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MILDBHCC_00901 5.43e-188 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MILDBHCC_00902 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MILDBHCC_00903 8.05e-278 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MILDBHCC_00904 4.19e-283 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MILDBHCC_00905 7.15e-277 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MILDBHCC_00906 9.41e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
MILDBHCC_00908 9.84e-195 supH - - S - - - haloacid dehalogenase-like hydrolase
MILDBHCC_00909 8.36e-260 - - - EGP - - - Major Facilitator Superfamily
MILDBHCC_00910 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MILDBHCC_00911 1.32e-217 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MILDBHCC_00912 1.18e-26 - - - S - - - Protein of unknown function (DUF3042)
MILDBHCC_00913 2.09e-76 yqhL - - P - - - Rhodanese-like protein
MILDBHCC_00914 3.31e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MILDBHCC_00915 2.67e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
MILDBHCC_00916 6.82e-128 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MILDBHCC_00917 3.09e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MILDBHCC_00918 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MILDBHCC_00919 0.0 - - - S - - - membrane
MILDBHCC_00920 5.34e-97 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MILDBHCC_00921 6.41e-261 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MILDBHCC_00922 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MILDBHCC_00923 5.46e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MILDBHCC_00924 1.19e-82 yodB - - K - - - Transcriptional regulator, HxlR family
MILDBHCC_00925 3.14e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MILDBHCC_00926 8.53e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MILDBHCC_00927 9.51e-217 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MILDBHCC_00928 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MILDBHCC_00929 1.89e-169 csrR - - K - - - response regulator
MILDBHCC_00930 3.13e-122 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MILDBHCC_00931 4.84e-278 ylbM - - S - - - Belongs to the UPF0348 family
MILDBHCC_00932 4.36e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MILDBHCC_00933 1.04e-142 yqeK - - H - - - Hydrolase, HD family
MILDBHCC_00934 2.34e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MILDBHCC_00935 1.37e-269 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MILDBHCC_00936 5.48e-114 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MILDBHCC_00937 6.48e-243 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MILDBHCC_00938 1.23e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MILDBHCC_00939 9.64e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MILDBHCC_00940 1.29e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MILDBHCC_00941 3.73e-303 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MILDBHCC_00942 1.43e-95 - - - S - - - Protein of unknown function (DUF3021)
MILDBHCC_00943 5.61e-98 - - - K - - - LytTr DNA-binding domain
MILDBHCC_00944 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MILDBHCC_00945 1.05e-199 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MILDBHCC_00946 8.86e-303 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
MILDBHCC_00947 8.41e-107 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MILDBHCC_00948 2.08e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MILDBHCC_00949 1.93e-204 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MILDBHCC_00950 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MILDBHCC_00951 1.17e-79 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MILDBHCC_00952 1.12e-154 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MILDBHCC_00953 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MILDBHCC_00954 2.29e-110 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
MILDBHCC_00955 8.43e-155 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MILDBHCC_00956 1.11e-70 ytpP - - CO - - - Thioredoxin
MILDBHCC_00957 5.68e-83 - - - - - - - -
MILDBHCC_00958 9.86e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MILDBHCC_00959 5.29e-282 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MILDBHCC_00960 1.38e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_00961 9.69e-99 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
MILDBHCC_00962 1.48e-84 - - - - - - - -
MILDBHCC_00963 8.07e-46 - - - S - - - YtxH-like protein
MILDBHCC_00964 2.5e-202 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MILDBHCC_00965 1.25e-236 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MILDBHCC_00966 0.0 yhaN - - L - - - AAA domain
MILDBHCC_00967 2.07e-281 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
MILDBHCC_00968 1.57e-73 yheA - - S - - - Belongs to the UPF0342 family
MILDBHCC_00969 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MILDBHCC_00970 3.74e-205 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MILDBHCC_00972 0.0 - - - S - - - M26 IgA1-specific Metallo-endopeptidase C-terminal region
MILDBHCC_00973 2.79e-59 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MILDBHCC_00974 1.82e-310 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MILDBHCC_00975 1.7e-101 - 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MILDBHCC_00976 6.6e-91 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MILDBHCC_00977 3.14e-145 - - - K ko:K02538 - ko00000,ko03000 PRD domain
MILDBHCC_00978 6.9e-150 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MILDBHCC_00979 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MILDBHCC_00980 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MILDBHCC_00981 1.55e-275 - - - S - - - Protein of unknown function (DUF2974)
MILDBHCC_00982 1.68e-175 - - - - - - - -
MILDBHCC_00983 2.03e-188 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MILDBHCC_00984 3.93e-220 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MILDBHCC_00985 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MILDBHCC_00986 6.29e-220 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MILDBHCC_00987 6.07e-60 - - - - - - - -
MILDBHCC_00988 0.0 - - - K - - - Sigma-54 interaction domain
MILDBHCC_00989 1.13e-71 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MILDBHCC_00990 1.79e-106 ptsB 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MILDBHCC_00991 3.18e-176 ptsC - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MILDBHCC_00992 2.69e-190 ptsD - - G ko:K02796,ko:K19509 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MILDBHCC_00993 8.75e-146 - - - S ko:K07507 - ko00000,ko02000 MgtC family
MILDBHCC_00994 2.64e-168 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
MILDBHCC_00996 8.35e-121 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MILDBHCC_00997 7.48e-162 - - - F - - - Glutamine amidotransferase class-I
MILDBHCC_00998 3.85e-144 ylbE - - GM - - - NAD(P)H-binding
MILDBHCC_00999 1.71e-105 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MILDBHCC_01000 5.29e-282 - - - P - - - Voltage gated chloride channel
MILDBHCC_01001 8.2e-245 - - - S - - - Bacteriocin helveticin-J
MILDBHCC_01002 7.34e-129 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MILDBHCC_01003 2.4e-207 - - - S ko:K07088 - ko00000 Membrane transport protein
MILDBHCC_01004 3.77e-174 - - - S ko:K07052 - ko00000 CAAX amino terminal protease
MILDBHCC_01005 9.83e-185 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MILDBHCC_01006 0.0 qacA - - EGP - - - Major Facilitator
MILDBHCC_01007 0.0 qacA - - EGP - - - Major Facilitator
MILDBHCC_01008 3.76e-89 - - - - - - - -
MILDBHCC_01010 2.19e-22 - - - - - - - -
MILDBHCC_01011 7.53e-107 - - - K - - - acetyltransferase
MILDBHCC_01012 1.98e-258 - - - S - - - PFAM Archaeal ATPase
MILDBHCC_01013 1.1e-187 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MILDBHCC_01014 1.34e-131 - - - S - - - Protein of unknown function (DUF1440)
MILDBHCC_01015 1.9e-191 - - - S - - - hydrolase
MILDBHCC_01016 3.45e-203 - - - K - - - Transcriptional regulator
MILDBHCC_01017 1.18e-308 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MILDBHCC_01018 5.79e-170 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
MILDBHCC_01019 3.14e-94 lacA 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
MILDBHCC_01020 1.17e-136 - 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
MILDBHCC_01021 4.47e-19 lacT - - K ko:K02531 - ko00000,ko03000 CAT RNA binding domain
MILDBHCC_01022 1.02e-121 lacT - - K ko:K02531 - ko00000,ko03000 CAT RNA binding domain
MILDBHCC_01023 1.62e-71 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MILDBHCC_01024 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
MILDBHCC_01025 0.0 lacG 3.2.1.21, 3.2.1.85 - G ko:K01220,ko:K05350 ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MILDBHCC_01026 1.53e-216 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MILDBHCC_01027 1.15e-143 - - - I - - - Acid phosphatase homologues
MILDBHCC_01028 0.0 - - - E - - - Phospholipase B
MILDBHCC_01029 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MILDBHCC_01030 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Contains amino acid permease domain
MILDBHCC_01031 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
MILDBHCC_01032 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MILDBHCC_01033 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Contains amino acid permease domain
MILDBHCC_01034 1.32e-196 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino acid permease
MILDBHCC_01035 3.63e-194 tdc 4.1.1.25 - E ko:K22330 ko00350,map00350 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
MILDBHCC_01036 2.41e-129 tdc 4.1.1.25 - E ko:K22330 ko00350,map00350 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
MILDBHCC_01037 6.1e-311 - - - E - - - amino acid
MILDBHCC_01038 8.86e-270 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
MILDBHCC_01039 1.06e-37 - - - - - - - -
MILDBHCC_01040 6.45e-91 rmaE - - K - - - helix_turn_helix multiple antibiotic resistance protein
MILDBHCC_01041 2.04e-107 - - - - - - - -
MILDBHCC_01042 7.25e-265 pepA - - E - - - M42 glutamyl aminopeptidase
MILDBHCC_01044 2.13e-149 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_01045 9.94e-166 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MILDBHCC_01046 1.56e-266 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
MILDBHCC_01047 1.02e-99 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
MILDBHCC_01048 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MILDBHCC_01049 0.0 - - - E - - - Peptidase family C69
MILDBHCC_01050 3.81e-275 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
MILDBHCC_01051 7.77e-199 - - - S - - - Alpha beta hydrolase
MILDBHCC_01052 8.75e-66 - - - K - - - Transcriptional regulator, MarR family
MILDBHCC_01053 5.48e-17 - - - K - - - Transcriptional regulator, MarR family
MILDBHCC_01054 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_01055 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
MILDBHCC_01056 1.1e-188 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MILDBHCC_01057 6.35e-176 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_01058 3.69e-192 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MILDBHCC_01059 1.5e-142 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MILDBHCC_01060 3.24e-139 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MILDBHCC_01061 1.68e-85 - - - - - - - -
MILDBHCC_01062 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MILDBHCC_01063 4.77e-165 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MILDBHCC_01064 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MILDBHCC_01065 8.35e-110 - - - S - - - Putative adhesin
MILDBHCC_01067 6.41e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MILDBHCC_01069 2.32e-260 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MILDBHCC_01070 7.53e-109 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MILDBHCC_01071 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MILDBHCC_01072 1.22e-269 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MILDBHCC_01073 1.3e-56 - - - H - - - Core-2/I-Branching enzyme
MILDBHCC_01074 5.75e-127 - - - M - - - transferase activity, transferring glycosyl groups
MILDBHCC_01075 2.79e-80 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
MILDBHCC_01076 3.63e-59 - - - G - - - Protein of unknown function (DUF563)
MILDBHCC_01077 7.92e-64 - - - M - - - Glycosyltransferase like family 2
MILDBHCC_01078 1.92e-48 - - - S - - - O-antigen ligase like membrane protein
MILDBHCC_01079 6.26e-156 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
MILDBHCC_01080 4.81e-178 cps3J - - M - - - Domain of unknown function (DUF4422)
MILDBHCC_01081 4.19e-104 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
MILDBHCC_01082 4.63e-177 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MILDBHCC_01083 1.69e-157 ywqD - - D - - - Capsular exopolysaccharide family
MILDBHCC_01084 3.02e-177 epsB - - M - - - biosynthesis protein
MILDBHCC_01085 1.74e-211 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MILDBHCC_01086 8.59e-103 - - - K - - - DNA-templated transcription, initiation
MILDBHCC_01087 6.23e-209 - - - - - - - -
MILDBHCC_01088 1.39e-156 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
MILDBHCC_01089 6.95e-283 - - - - - - - -
MILDBHCC_01090 9.34e-113 - - - S - - - Domain of unknown function (DUF4767)
MILDBHCC_01091 9.4e-148 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
MILDBHCC_01093 1.1e-108 - - - - - - - -
MILDBHCC_01094 6.6e-115 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MILDBHCC_01095 1.26e-132 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MILDBHCC_01096 2.79e-293 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MILDBHCC_01097 2e-275 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MILDBHCC_01098 2.45e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MILDBHCC_01099 1.58e-203 - - - - - - - -
MILDBHCC_01100 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MILDBHCC_01101 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MILDBHCC_01102 1.27e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MILDBHCC_01103 3.38e-227 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MILDBHCC_01104 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MILDBHCC_01105 5.48e-139 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MILDBHCC_01106 8.06e-234 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MILDBHCC_01107 3.34e-112 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MILDBHCC_01108 2.04e-123 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MILDBHCC_01109 4e-66 ylbG - - S - - - UPF0298 protein
MILDBHCC_01110 1.36e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MILDBHCC_01111 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MILDBHCC_01112 9.73e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MILDBHCC_01113 3.08e-47 ykzG - - S - - - Belongs to the UPF0356 family
MILDBHCC_01114 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MILDBHCC_01115 6.85e-227 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MILDBHCC_01116 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MILDBHCC_01117 3.57e-151 - - - S - - - repeat protein
MILDBHCC_01118 5.5e-162 pgm - - G - - - Phosphoglycerate mutase family
MILDBHCC_01119 9.01e-278 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MILDBHCC_01120 1.27e-76 XK27_04120 - - S - - - Putative amino acid metabolism
MILDBHCC_01121 3.68e-277 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MILDBHCC_01122 1.02e-164 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MILDBHCC_01123 6.32e-52 - - - - - - - -
MILDBHCC_01124 1.81e-133 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MILDBHCC_01125 1.37e-45 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MILDBHCC_01126 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MILDBHCC_01127 4.46e-162 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MILDBHCC_01128 1.39e-187 ylmH - - S - - - S4 domain protein
MILDBHCC_01129 1.36e-47 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
MILDBHCC_01130 9.26e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MILDBHCC_01131 6.35e-311 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MILDBHCC_01132 5.2e-309 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MILDBHCC_01133 2.6e-196 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MILDBHCC_01134 3.2e-264 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MILDBHCC_01135 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MILDBHCC_01136 1.82e-226 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MILDBHCC_01137 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MILDBHCC_01138 3.95e-73 ftsL - - D - - - Cell division protein FtsL
MILDBHCC_01139 1.17e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MILDBHCC_01140 1.89e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MILDBHCC_01141 2.2e-68 - - - S - - - Protein of unknown function (DUF3397)
MILDBHCC_01142 2.36e-19 - - - S - - - Protein of unknown function (DUF4044)
MILDBHCC_01143 3.99e-123 mreD - - - ko:K03571 - ko00000,ko03036 -
MILDBHCC_01144 1.17e-188 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MILDBHCC_01145 3.11e-225 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MILDBHCC_01146 3.73e-143 radC - - L ko:K03630 - ko00000 DNA repair protein
MILDBHCC_01147 2.31e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
MILDBHCC_01148 3.31e-301 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MILDBHCC_01149 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MILDBHCC_01150 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MILDBHCC_01151 1.91e-230 - - - C - - - Glycerophosphoryl diester phosphodiesterase family
MILDBHCC_01152 3.13e-159 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MILDBHCC_01153 4.43e-291 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MILDBHCC_01154 6.1e-276 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MILDBHCC_01155 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MILDBHCC_01157 7.54e-143 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MILDBHCC_01158 1.06e-109 - - - S - - - Protein of unknown function (DUF1694)
MILDBHCC_01159 9.21e-304 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MILDBHCC_01160 9.34e-08 - - - - - - - -
MILDBHCC_01161 3.52e-106 uspA - - T - - - universal stress protein
MILDBHCC_01162 1.59e-71 - - - K - - - Acetyltransferase (GNAT) domain
MILDBHCC_01163 3.96e-314 ynbB - - P - - - aluminum resistance
MILDBHCC_01164 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
MILDBHCC_01165 0.0 - - - E - - - Amino acid permease
MILDBHCC_01166 9.1e-205 - 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MILDBHCC_01167 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MILDBHCC_01168 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MILDBHCC_01169 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MILDBHCC_01170 7.67e-66 - - - S - - - Cupredoxin-like domain
MILDBHCC_01171 1.2e-83 - - - S - - - Cupredoxin-like domain
MILDBHCC_01172 4.61e-97 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
MILDBHCC_01173 1.12e-117 - - - - - - - -
MILDBHCC_01174 4.92e-94 - - - - - - - -
MILDBHCC_01175 2.42e-91 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MILDBHCC_01176 4.93e-98 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
MILDBHCC_01177 1.13e-291 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MILDBHCC_01178 5.43e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MILDBHCC_01179 2.47e-166 - - - K - - - helix_turn_helix, mercury resistance
MILDBHCC_01180 6.61e-295 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MILDBHCC_01181 2.33e-301 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MILDBHCC_01182 3.29e-161 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MILDBHCC_01183 8.43e-155 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MILDBHCC_01184 5.45e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MILDBHCC_01185 8.84e-207 - - - S - - - Aldo/keto reductase family
MILDBHCC_01186 1.8e-167 - - - S ko:K07090 - ko00000 membrane transporter protein
MILDBHCC_01187 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MILDBHCC_01188 1.06e-203 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MILDBHCC_01189 2.55e-247 yleB 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
MILDBHCC_01190 5.87e-195 yleF - - K - - - Helix-turn-helix domain, rpiR family
MILDBHCC_01191 1.83e-256 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
MILDBHCC_01192 2.85e-214 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
MILDBHCC_01193 4.96e-226 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MILDBHCC_01194 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MILDBHCC_01195 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MILDBHCC_01196 1.9e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
MILDBHCC_01197 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MILDBHCC_01198 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_01199 3.18e-261 - - - S - - - DUF218 domain
MILDBHCC_01200 4.83e-145 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MILDBHCC_01201 1.86e-124 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
MILDBHCC_01202 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
MILDBHCC_01205 2.11e-113 yhaH - - S - - - Protein of unknown function (DUF805)
MILDBHCC_01206 7.06e-147 - - - S - - - Protein of unknown function (DUF969)
MILDBHCC_01207 5.84e-201 - - - S - - - Protein of unknown function (DUF979)
MILDBHCC_01208 2.07e-155 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MILDBHCC_01209 2.33e-47 - - - - - - - -
MILDBHCC_01210 2.24e-204 mutR - - K - - - Helix-turn-helix XRE-family like proteins
MILDBHCC_01211 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MILDBHCC_01212 1.81e-141 - - - S - - - Putative adhesin
MILDBHCC_01213 1.19e-258 napA - - P - - - Sodium/hydrogen exchanger family
MILDBHCC_01214 0.0 cadA - - P - - - P-type ATPase
MILDBHCC_01215 1.66e-111 ykuL - - S - - - (CBS) domain
MILDBHCC_01216 5.45e-61 - - - - - - - -
MILDBHCC_01217 1.88e-66 - - - - - - - -
MILDBHCC_01218 1.18e-78 - - - - - - - -
MILDBHCC_01220 2.57e-272 - - - S - - - Membrane
MILDBHCC_01221 6.13e-52 - - - - - - - -
MILDBHCC_01222 9.7e-07 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
MILDBHCC_01223 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MILDBHCC_01224 4.7e-303 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MILDBHCC_01225 5.16e-50 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MILDBHCC_01226 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MILDBHCC_01227 7.18e-189 pbpX2 - - V - - - Beta-lactamase
MILDBHCC_01228 1.97e-275 - - - E - - - Major Facilitator Superfamily
MILDBHCC_01229 2.11e-53 - - - - - - - -
MILDBHCC_01230 1.23e-312 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MILDBHCC_01231 9.68e-219 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MILDBHCC_01232 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
MILDBHCC_01233 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MILDBHCC_01234 4.38e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MILDBHCC_01235 9.65e-95 - - - S - - - GtrA-like protein
MILDBHCC_01236 7.72e-228 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
MILDBHCC_01237 6.21e-152 - - - - - - - -
MILDBHCC_01238 3.83e-196 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MILDBHCC_01239 9.65e-218 yqhA - - G - - - Aldose 1-epimerase
MILDBHCC_01240 1.59e-268 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MILDBHCC_01241 1.2e-145 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MILDBHCC_01242 0.0 XK27_08315 - - M - - - Sulfatase
MILDBHCC_01243 1.86e-308 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MILDBHCC_01245 0.0 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MILDBHCC_01246 2.16e-58 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MILDBHCC_01247 2.03e-170 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MILDBHCC_01248 5.17e-166 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MILDBHCC_01249 1.41e-189 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MILDBHCC_01250 4.21e-214 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MILDBHCC_01251 6.92e-173 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MILDBHCC_01252 3.06e-158 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MILDBHCC_01253 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MILDBHCC_01254 2.3e-60 - - - - - - - -
MILDBHCC_01255 4.49e-97 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MILDBHCC_01256 1.52e-68 - - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MILDBHCC_01257 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MILDBHCC_01258 2.35e-107 - - - - - - - -
MILDBHCC_01259 1.04e-175 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MILDBHCC_01260 1.27e-98 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MILDBHCC_01261 3.42e-167 - - - K ko:K03489 - ko00000,ko03000 UTRA
MILDBHCC_01262 7.28e-92 - - - S - - - Domain of unknown function (DUF3284)
MILDBHCC_01263 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MILDBHCC_01264 1.15e-174 - - - K ko:K03492 - ko00000,ko03000 UTRA
MILDBHCC_01265 3.56e-68 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
MILDBHCC_01266 7.13e-56 - - - - - - - -
MILDBHCC_01267 3.44e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MILDBHCC_01268 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MILDBHCC_01269 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MILDBHCC_01270 6.66e-201 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MILDBHCC_01271 8.03e-151 - - - - - - - -
MILDBHCC_01273 1.03e-149 - - - E - - - Belongs to the SOS response-associated peptidase family
MILDBHCC_01274 2.46e-247 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MILDBHCC_01275 9.68e-119 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
MILDBHCC_01276 3.58e-128 - - - S ko:K06872 - ko00000 TPM domain
MILDBHCC_01277 5.01e-233 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
MILDBHCC_01278 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MILDBHCC_01279 3.86e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MILDBHCC_01280 4.59e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MILDBHCC_01281 1.15e-206 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MILDBHCC_01282 1.22e-48 veg - - S - - - Biofilm formation stimulator VEG
MILDBHCC_01283 1.91e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MILDBHCC_01284 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MILDBHCC_01285 2.27e-222 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MILDBHCC_01286 1.01e-225 yvdE - - K - - - helix_turn _helix lactose operon repressor
MILDBHCC_01287 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MILDBHCC_01288 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MILDBHCC_01289 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MILDBHCC_01290 4.64e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MILDBHCC_01291 1.31e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MILDBHCC_01292 1.48e-289 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MILDBHCC_01293 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MILDBHCC_01294 3.99e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MILDBHCC_01295 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
MILDBHCC_01296 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MILDBHCC_01297 4.71e-89 - - - S - - - Domain of unknown function (DUF1934)
MILDBHCC_01298 1.03e-90 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MILDBHCC_01299 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MILDBHCC_01300 4.39e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MILDBHCC_01301 1.6e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MILDBHCC_01302 9.63e-136 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MILDBHCC_01303 2.16e-167 - - - K - - - Psort location CytoplasmicMembrane, score
MILDBHCC_01304 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MILDBHCC_01305 3.64e-76 ydeP - - K - - - Transcriptional regulator, HxlR family
MILDBHCC_01306 1.32e-188 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MILDBHCC_01307 1.8e-36 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MILDBHCC_01309 2.91e-139 - - - K - - - transcriptional regulator
MILDBHCC_01310 1.79e-122 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MILDBHCC_01311 4.22e-219 - - - K - - - Helix-turn-helix
MILDBHCC_01312 3.76e-145 - - - S - - - NADPH-dependent FMN reductase
MILDBHCC_01313 2.31e-122 - - - K - - - Bacterial regulatory proteins, tetR family
MILDBHCC_01314 1.3e-86 yjdF3 - - S - - - Protein of unknown function (DUF2992)
MILDBHCC_01315 1.16e-142 - - - S - - - Membrane
MILDBHCC_01316 1.13e-137 - - - K ko:K06977 - ko00000 acetyltransferase
MILDBHCC_01317 2.95e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MILDBHCC_01318 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MILDBHCC_01319 3.07e-39 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MILDBHCC_01320 1.18e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MILDBHCC_01321 5.9e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MILDBHCC_01322 4.94e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MILDBHCC_01323 4.74e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MILDBHCC_01324 3.72e-238 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MILDBHCC_01326 0.0 ycaM - - E - - - amino acid
MILDBHCC_01327 3.74e-130 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MILDBHCC_01328 2.02e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MILDBHCC_01329 1.54e-247 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MILDBHCC_01330 1.58e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MILDBHCC_01331 2.04e-117 - - - S - - - Short repeat of unknown function (DUF308)
MILDBHCC_01332 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MILDBHCC_01333 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MILDBHCC_01334 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MILDBHCC_01335 1.66e-206 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MILDBHCC_01336 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MILDBHCC_01337 8.11e-263 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MILDBHCC_01338 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
MILDBHCC_01339 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MILDBHCC_01340 5.52e-241 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MILDBHCC_01341 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MILDBHCC_01342 4.7e-237 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MILDBHCC_01343 2.96e-242 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MILDBHCC_01344 2.57e-19 - - - L - - - Caulimovirus viroplasmin
MILDBHCC_01346 5.2e-41 - - - D - - - nuclear chromosome segregation
MILDBHCC_01347 3.12e-223 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MILDBHCC_01348 2.72e-238 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MILDBHCC_01349 5.09e-201 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MILDBHCC_01350 1.67e-222 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MILDBHCC_01351 6.45e-41 - - - - - - - -
MILDBHCC_01352 3.42e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MILDBHCC_01353 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MILDBHCC_01354 3.97e-125 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MILDBHCC_01355 1.84e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MILDBHCC_01356 3.08e-286 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MILDBHCC_01357 2.31e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MILDBHCC_01358 9.48e-262 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MILDBHCC_01359 0.0 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MILDBHCC_01360 2.99e-248 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MILDBHCC_01361 7.62e-126 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MILDBHCC_01362 4.22e-178 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
MILDBHCC_01363 1.05e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MILDBHCC_01364 1.56e-294 ymfH - - S - - - Peptidase M16
MILDBHCC_01365 1.43e-291 ymfF - - S - - - Peptidase M16 inactive domain protein
MILDBHCC_01366 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MILDBHCC_01367 6.82e-99 - - - S - - - Protein of unknown function (DUF1149)
MILDBHCC_01368 8e-136 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MILDBHCC_01369 2.09e-267 XK27_05220 - - S - - - AI-2E family transporter
MILDBHCC_01370 1.99e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MILDBHCC_01371 6.1e-256 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MILDBHCC_01372 1.23e-67 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MILDBHCC_01375 3.98e-190 - - - S - - - hydrolase
MILDBHCC_01376 0.0 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
MILDBHCC_01377 4.51e-111 - - - L ko:K07491 - ko00000 Transposase IS200 like
MILDBHCC_01378 3.61e-213 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MILDBHCC_01379 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MILDBHCC_01380 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MILDBHCC_01381 2.23e-65 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MILDBHCC_01382 1.3e-263 camS - - S - - - sex pheromone
MILDBHCC_01383 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MILDBHCC_01384 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MILDBHCC_01385 1.2e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MILDBHCC_01386 2.91e-132 - - - S - - - ECF transporter, substrate-specific component
MILDBHCC_01388 1.07e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MILDBHCC_01389 7.76e-169 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
MILDBHCC_01390 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MILDBHCC_01391 4.92e-290 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MILDBHCC_01392 4.62e-183 - - - - - - - -
MILDBHCC_01393 0.0 - - - V - - - ABC transporter transmembrane region
MILDBHCC_01394 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MILDBHCC_01395 0.0 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
MILDBHCC_01396 1.58e-199 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MILDBHCC_01397 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MILDBHCC_01398 0.0 - - - S - - - Glycosyltransferase like family 2
MILDBHCC_01399 7.27e-266 - - - M - - - Glycosyl transferases group 1
MILDBHCC_01400 6.86e-174 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MILDBHCC_01401 1.44e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
MILDBHCC_01402 2.57e-158 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
MILDBHCC_01403 2.62e-244 - - - - - - - -
MILDBHCC_01404 1.19e-69 XK27_05625 - - P - - - Rhodanese Homology Domain
MILDBHCC_01407 5.98e-212 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
MILDBHCC_01408 1.21e-45 - - - K - - - SIS domain
MILDBHCC_01409 2.51e-49 - - - S - - - Bacterial protein of unknown function (DUF898)
MILDBHCC_01411 4.88e-169 - - - M - - - LysM domain protein
MILDBHCC_01412 5.02e-166 - - - M - - - LysM domain protein
MILDBHCC_01413 5.68e-174 - - - S - - - Putative ABC-transporter type IV
MILDBHCC_01414 4.37e-79 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
MILDBHCC_01415 2.83e-121 - - - K - - - acetyltransferase
MILDBHCC_01417 1.53e-210 yvgN - - C - - - Aldo keto reductase
MILDBHCC_01418 2.92e-313 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
MILDBHCC_01419 5.05e-88 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
MILDBHCC_01420 1.21e-241 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MILDBHCC_01421 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
MILDBHCC_01422 0.0 - - - P - - - P-loop Domain of unknown function (DUF2791)
MILDBHCC_01423 0.0 - - - S - - - TerB-C domain
MILDBHCC_01424 9.59e-49 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
MILDBHCC_01425 7.22e-105 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
MILDBHCC_01426 2.91e-94 - - - - - - - -
MILDBHCC_01427 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MILDBHCC_01428 1.24e-312 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MILDBHCC_01430 3.69e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MILDBHCC_01431 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MILDBHCC_01432 1.53e-18 - - - K - - - Helix-turn-helix domain
MILDBHCC_01433 9.83e-148 - - - - - - - -
MILDBHCC_01435 0.0 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
MILDBHCC_01436 9.81e-20 - - - - - - - -
MILDBHCC_01437 2.29e-42 - - - - - - - -
MILDBHCC_01438 8.84e-90 - - - EGP - - - Major facilitator Superfamily
MILDBHCC_01439 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MILDBHCC_01440 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MILDBHCC_01441 3.1e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MILDBHCC_01442 1.63e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MILDBHCC_01443 2.39e-75 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MILDBHCC_01444 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MILDBHCC_01445 4.21e-266 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MILDBHCC_01446 1.24e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MILDBHCC_01447 7.97e-295 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MILDBHCC_01448 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MILDBHCC_01449 1.08e-56 yrzL - - S - - - Belongs to the UPF0297 family
MILDBHCC_01450 1.68e-94 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MILDBHCC_01451 3.49e-55 yrzB - - S - - - Belongs to the UPF0473 family
MILDBHCC_01452 1.96e-120 cvpA - - S - - - Colicin V production protein
MILDBHCC_01453 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MILDBHCC_01454 8.93e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MILDBHCC_01455 3.65e-90 yslB - - S - - - Protein of unknown function (DUF2507)
MILDBHCC_01456 1.23e-186 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MILDBHCC_01457 3.6e-152 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MILDBHCC_01458 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MILDBHCC_01459 2.35e-180 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MILDBHCC_01460 1.51e-67 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MILDBHCC_01461 1.21e-177 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MILDBHCC_01462 2.92e-37 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MILDBHCC_01463 8.01e-66 - - - - - - - -
MILDBHCC_01464 2.55e-269 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MILDBHCC_01465 4.41e-224 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MILDBHCC_01466 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin binding protein transpeptidase domain
MILDBHCC_01467 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MILDBHCC_01468 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MILDBHCC_01469 1.15e-73 - - - - - - - -
MILDBHCC_01470 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MILDBHCC_01471 1.62e-123 yutD - - S - - - Protein of unknown function (DUF1027)
MILDBHCC_01472 1.2e-190 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MILDBHCC_01473 3.32e-135 - - - S - - - Protein of unknown function (DUF1461)
MILDBHCC_01474 8.39e-151 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MILDBHCC_01475 7.44e-230 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MILDBHCC_01476 8.2e-81 yugI - - J ko:K07570 - ko00000 general stress protein
MILDBHCC_01477 2.35e-255 - - - S - - - Sterol carrier protein domain
MILDBHCC_01478 4.23e-213 - - - I - - - Acyltransferase
MILDBHCC_01479 7.46e-149 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MILDBHCC_01480 8.33e-185 - - - K - - - Helix-turn-helix domain
MILDBHCC_01481 7.74e-257 - 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Involved in molybdopterin and thiamine biosynthesis, family 2
MILDBHCC_01482 3.22e-243 - - - EGP - - - Major Facilitator Superfamily
MILDBHCC_01483 8.09e-169 - - - S - - - Protein of unknown function (DUF975)
MILDBHCC_01484 4.52e-178 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MILDBHCC_01485 3.05e-198 yitS - - S - - - EDD domain protein, DegV family
MILDBHCC_01486 1.07e-23 - - - - - - - -
MILDBHCC_01487 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MILDBHCC_01488 3.37e-181 - - - K - - - Helix-turn-helix domain
MILDBHCC_01489 0.0 fusA1 - - J - - - elongation factor G
MILDBHCC_01490 2.75e-165 eriC - - P ko:K03281 - ko00000 chloride
MILDBHCC_01491 2.24e-114 eriC - - P ko:K03281 - ko00000 chloride
MILDBHCC_01492 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MILDBHCC_01493 1.32e-157 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
MILDBHCC_01494 2.77e-248 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
MILDBHCC_01495 4.72e-212 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MILDBHCC_01496 1.5e-20 - - - S - - - CsbD-like
MILDBHCC_01497 1.83e-54 - - - S - - - Transglycosylase associated protein
MILDBHCC_01498 3.75e-206 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MILDBHCC_01499 0.0 - - - L - - - Helicase C-terminal domain protein
MILDBHCC_01500 5.56e-177 - - - S - - - Alpha beta hydrolase
MILDBHCC_01502 2.57e-40 - - - - - - - -
MILDBHCC_01504 1.77e-22 - - - - - - - -
MILDBHCC_01505 5.92e-35 - - - - - - - -
MILDBHCC_01506 6.19e-224 ydbI - - K - - - AI-2E family transporter
MILDBHCC_01507 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
MILDBHCC_01508 4.6e-271 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MILDBHCC_01509 8.92e-136 - - - E - - - GDSL-like Lipase/Acylhydrolase
MILDBHCC_01510 9.23e-245 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MILDBHCC_01511 0.0 - - - S - - - domain, Protein
MILDBHCC_01512 4.13e-34 - - - M - - - LPXTG-motif cell wall anchor domain protein
MILDBHCC_01513 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MILDBHCC_01514 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MILDBHCC_01515 7.7e-310 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MILDBHCC_01516 1.09e-171 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MILDBHCC_01517 8.35e-229 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MILDBHCC_01518 5.19e-111 - - - S - - - Peptidase propeptide and YPEB domain
MILDBHCC_01519 5.29e-238 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MILDBHCC_01520 0.0 - - - P - - - Major Facilitator Superfamily
MILDBHCC_01521 7.19e-314 - - - P - - - Major Facilitator Superfamily
MILDBHCC_01522 3.48e-212 arbZ - - I - - - Phosphate acyltransferases
MILDBHCC_01523 2.24e-239 - - - M - - - Glycosyl transferase family 8
MILDBHCC_01524 3.43e-234 - - - M - - - Glycosyl transferase family 8
MILDBHCC_01525 2.52e-199 arbx - - M - - - Glycosyl transferase family 8
MILDBHCC_01526 3.43e-189 - - - I - - - Acyl-transferase
MILDBHCC_01528 8.21e-27 - - - UW - - - Tetratricopeptide repeat
MILDBHCC_01529 3.35e-213 - - - S - - - glycosyl transferase family 2
MILDBHCC_01530 2.19e-250 - - - M - - - transferase activity, transferring glycosyl groups
MILDBHCC_01531 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MILDBHCC_01532 3.12e-239 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MILDBHCC_01533 1.1e-132 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MILDBHCC_01534 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MILDBHCC_01535 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MILDBHCC_01536 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MILDBHCC_01537 5.57e-104 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MILDBHCC_01538 1.62e-179 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MILDBHCC_01539 3.08e-115 - - - K ko:K03091 - ko00000,ko03021 sigma factor activity
MILDBHCC_01540 5.9e-46 - - - - - - - -
MILDBHCC_01541 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MILDBHCC_01542 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MILDBHCC_01543 1.18e-291 - - - G - - - Major Facilitator Superfamily
MILDBHCC_01544 2.23e-238 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MILDBHCC_01545 1.48e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MILDBHCC_01546 8.06e-17 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MILDBHCC_01547 6.09e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MILDBHCC_01548 1.89e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MILDBHCC_01549 2.9e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MILDBHCC_01550 1.96e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MILDBHCC_01551 6.39e-150 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
MILDBHCC_01552 6.64e-187 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MILDBHCC_01553 1.78e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MILDBHCC_01554 3.25e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MILDBHCC_01555 2.69e-182 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
MILDBHCC_01556 3.25e-44 - - - - - - - -
MILDBHCC_01557 4.73e-146 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MILDBHCC_01558 3.9e-30 - - - - - - - -
MILDBHCC_01559 1.52e-190 - - - - - - - -
MILDBHCC_01560 9.83e-66 - - - S - - - Protein conserved in bacteria
MILDBHCC_01561 4.11e-110 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MILDBHCC_01562 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MILDBHCC_01563 1.9e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MILDBHCC_01564 2.53e-139 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MILDBHCC_01565 3.03e-44 - - - S - - - Protein of unknown function (DUF2508)
MILDBHCC_01566 2.92e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MILDBHCC_01567 1.24e-68 yaaQ - - S - - - Cyclic-di-AMP receptor
MILDBHCC_01568 2.58e-193 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MILDBHCC_01569 3.33e-78 yabA - - L - - - Involved in initiation control of chromosome replication
MILDBHCC_01570 2.81e-197 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MILDBHCC_01571 5.47e-179 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MILDBHCC_01572 2.13e-111 - - - S - - - ECF transporter, substrate-specific component
MILDBHCC_01573 1.44e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MILDBHCC_01574 2.49e-122 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MILDBHCC_01575 5.57e-247 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MILDBHCC_01576 2.51e-304 - - - D - - - nuclear chromosome segregation
MILDBHCC_01577 7.14e-54 - - - - - - - -
MILDBHCC_01578 1.16e-148 - - - - - - - -
MILDBHCC_01579 0.0 eriC - - P ko:K03281 - ko00000 chloride
MILDBHCC_01580 4.91e-241 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MILDBHCC_01581 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MILDBHCC_01582 1.98e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MILDBHCC_01583 2.98e-127 - - - L - - - oxidized base lesion DNA N-glycosylase activity
MILDBHCC_01584 2.89e-31 - - - L - - - oxidized base lesion DNA N-glycosylase activity
MILDBHCC_01586 0.0 steT - - E ko:K03294 - ko00000 amino acid
MILDBHCC_01587 8.82e-276 - - - L - - - Belongs to the 'phage' integrase family
MILDBHCC_01588 1.45e-42 - - - - - - - -
MILDBHCC_01589 6.3e-137 - - - EP - - - Plasmid replication protein
MILDBHCC_01590 1.15e-105 - - - EP - - - Plasmid replication protein
MILDBHCC_01591 4.15e-120 - - - - - - - -
MILDBHCC_01592 9.41e-167 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MILDBHCC_01593 3.11e-71 - - - - - - - -
MILDBHCC_01594 4.15e-232 - - - - - - - -
MILDBHCC_01595 1.19e-77 cadX - - K ko:K21903 - ko00000,ko03000 Bacterial regulatory protein, arsR family
MILDBHCC_01596 8.34e-132 cadD - - P - - - Cadmium resistance transporter
MILDBHCC_01598 0.0 - - - - - - - -
MILDBHCC_01599 1.39e-279 - - - I - - - Protein of unknown function (DUF2974)
MILDBHCC_01600 5.17e-218 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MILDBHCC_01601 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MILDBHCC_01602 8.13e-99 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MILDBHCC_01603 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MILDBHCC_01604 1.42e-216 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MILDBHCC_01605 1.33e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MILDBHCC_01606 5.89e-109 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MILDBHCC_01607 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MILDBHCC_01608 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MILDBHCC_01609 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MILDBHCC_01610 7.88e-267 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MILDBHCC_01611 5.33e-30 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
MILDBHCC_01612 1.46e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MILDBHCC_01613 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MILDBHCC_01614 6.59e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MILDBHCC_01615 1.8e-79 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MILDBHCC_01616 4.86e-201 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MILDBHCC_01617 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MILDBHCC_01618 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MILDBHCC_01619 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MILDBHCC_01620 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MILDBHCC_01621 0.0 eriC - - P ko:K03281 - ko00000 chloride
MILDBHCC_01622 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MILDBHCC_01624 8.09e-206 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko01000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MILDBHCC_01625 9.59e-266 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MILDBHCC_01626 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MILDBHCC_01627 1.09e-90 - - - S - - - Iron-sulphur cluster biosynthesis
MILDBHCC_01628 3.14e-310 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
MILDBHCC_01629 4.01e-181 - - - S - - - PAS domain
MILDBHCC_01630 3.28e-92 - - - K ko:K03710 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MILDBHCC_01631 1.31e-92 - 2.7.1.191 - K ko:K02745,ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MILDBHCC_01632 3.63e-162 - - - G ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MILDBHCC_01633 4.66e-158 agaD - - G ko:K02747,ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MILDBHCC_01634 3.65e-52 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MILDBHCC_01635 2.42e-69 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MILDBHCC_01636 0.0 - - - GM ko:K13732 ko05100,map05100 ko00000,ko00001 domain, Protein
MILDBHCC_01637 1.63e-186 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MILDBHCC_01638 2.3e-118 - - - S - - - PAS domain
MILDBHCC_01639 4.76e-307 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MILDBHCC_01640 4.73e-97 - - - S - - - Protein of unknown function (DUF3290)
MILDBHCC_01641 1.19e-143 yviA - - S - - - Protein of unknown function (DUF421)
MILDBHCC_01642 1.83e-193 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MILDBHCC_01643 1.83e-231 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
MILDBHCC_01644 9.66e-252 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
MILDBHCC_01645 2.52e-199 dkgB - - S - - - reductase
MILDBHCC_01646 4.84e-196 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MILDBHCC_01647 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MILDBHCC_01648 8.41e-260 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
MILDBHCC_01649 3.57e-201 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
MILDBHCC_01650 4.82e-189 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MILDBHCC_01651 4.66e-314 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
MILDBHCC_01652 9.33e-310 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MILDBHCC_01653 4.76e-75 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MILDBHCC_01654 1.92e-102 yybA - - K - - - Transcriptional regulator
MILDBHCC_01655 3.57e-120 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MILDBHCC_01656 4.59e-107 yjcF - - S - - - Acetyltransferase (GNAT) domain
MILDBHCC_01657 1.86e-213 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
MILDBHCC_01658 4.44e-204 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MILDBHCC_01659 1.8e-124 yobS - - K - - - Bacterial regulatory proteins, tetR family
MILDBHCC_01660 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MILDBHCC_01661 2.3e-187 - - - S - - - haloacid dehalogenase-like hydrolase
MILDBHCC_01662 2.6e-164 - - - S - - - SNARE associated Golgi protein
MILDBHCC_01663 4.78e-226 - - - - - - - -
MILDBHCC_01664 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MILDBHCC_01665 4.68e-198 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MILDBHCC_01666 3.32e-201 - - - I - - - alpha/beta hydrolase fold
MILDBHCC_01667 2.53e-139 - - - S - - - SNARE associated Golgi protein
MILDBHCC_01668 6.85e-132 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MILDBHCC_01669 6.46e-302 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MILDBHCC_01670 2.91e-148 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
MILDBHCC_01671 7.1e-152 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
MILDBHCC_01672 2.3e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_01673 1.13e-191 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MILDBHCC_01674 1.84e-155 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MILDBHCC_01675 2.24e-193 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MILDBHCC_01676 7.64e-313 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MILDBHCC_01677 5.15e-79 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
MILDBHCC_01678 7.68e-161 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MILDBHCC_01679 7.71e-188 - - - - - - - -
MILDBHCC_01680 7.02e-183 - - - - - - - -
MILDBHCC_01681 6.46e-49 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MILDBHCC_01682 2.06e-192 - - - - - - - -
MILDBHCC_01684 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MILDBHCC_01685 1.1e-49 - - - - - - - -
MILDBHCC_01686 4.93e-82 - - - - - - - -
MILDBHCC_01687 6.61e-15 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MILDBHCC_01688 2.65e-108 - - - L - - - transposase activity
MILDBHCC_01689 5.06e-31 - - - - - - - -
MILDBHCC_01690 7.35e-134 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MILDBHCC_01691 7.7e-169 - - - - - - - -
MILDBHCC_01692 6.25e-221 - - - - - - - -
MILDBHCC_01693 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MILDBHCC_01694 5.06e-68 ybjQ - - S - - - Belongs to the UPF0145 family
MILDBHCC_01695 1.38e-230 - - - S - - - DUF218 domain
MILDBHCC_01696 6.65e-193 yxeH - - S - - - hydrolase
MILDBHCC_01697 0.0 - - - I - - - Protein of unknown function (DUF2974)
MILDBHCC_01698 3.18e-153 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MILDBHCC_01699 1.23e-166 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MILDBHCC_01700 3.21e-214 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MILDBHCC_01701 6.39e-121 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MILDBHCC_01702 1.34e-232 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MILDBHCC_01703 5.38e-309 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MILDBHCC_01704 4.57e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MILDBHCC_01705 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MILDBHCC_01706 3.27e-118 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MILDBHCC_01707 1.28e-135 pncA - - Q - - - Isochorismatase family
MILDBHCC_01708 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MILDBHCC_01709 3.8e-274 - - - M - - - Glycosyl transferases group 1
MILDBHCC_01710 4.35e-119 alkD - - L - - - DNA alkylation repair enzyme
MILDBHCC_01712 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MILDBHCC_01713 5.69e-280 yfmL - - L - - - DEAD DEAH box helicase
MILDBHCC_01714 1.91e-175 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MILDBHCC_01715 1.39e-296 - - - E ko:K03294 - ko00000 amino acid
MILDBHCC_01716 8.59e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MILDBHCC_01717 4.03e-301 yhdP - - S - - - Transporter associated domain
MILDBHCC_01718 2.24e-169 - - - - - - - -
MILDBHCC_01719 5.05e-153 - - - C - - - nitroreductase
MILDBHCC_01720 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MILDBHCC_01721 3.01e-180 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MILDBHCC_01722 6.15e-69 - - - S - - - Enterocin A Immunity
MILDBHCC_01723 1.39e-171 gntR - - K - - - UbiC transcription regulator-associated domain protein
MILDBHCC_01724 9.72e-225 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MILDBHCC_01725 7.73e-164 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MILDBHCC_01726 4.72e-212 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MILDBHCC_01727 1.98e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MILDBHCC_01728 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
MILDBHCC_01729 8.28e-152 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MILDBHCC_01730 1.62e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MILDBHCC_01731 4.68e-191 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MILDBHCC_01732 1.44e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MILDBHCC_01733 8.44e-217 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MILDBHCC_01734 2.73e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MILDBHCC_01735 1.13e-124 - - - K - - - Acetyltransferase (GNAT) domain
MILDBHCC_01736 3.39e-168 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_01737 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MILDBHCC_01738 7.86e-207 - - - S - - - Phospholipase, patatin family
MILDBHCC_01739 2.07e-146 - - - K ko:K02538 - ko00000,ko03000 PRD domain
MILDBHCC_01740 2.47e-125 - - - - - - - -
MILDBHCC_01741 1.3e-201 - - - S - - - PD-(D/E)XK nuclease family transposase
MILDBHCC_01742 4.02e-194 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Belongs to the aminoglycoside phosphotransferase family
MILDBHCC_01743 2.12e-253 flp - - V - - - Beta-lactamase
MILDBHCC_01745 4.19e-50 ung2 - - L - - - Uracil-DNA glycosylase
MILDBHCC_01746 5.03e-148 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
MILDBHCC_01747 5.86e-120 dpsB - - P - - - Belongs to the Dps family
MILDBHCC_01748 1.35e-46 - - - C - - - Heavy-metal-associated domain
MILDBHCC_01749 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
MILDBHCC_01750 8.91e-142 - - - - - - - -
MILDBHCC_01751 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MILDBHCC_01752 2.58e-155 - - - S ko:K01992,ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
MILDBHCC_01753 3.28e-166 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_01754 1.56e-311 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MILDBHCC_01755 5.12e-207 XK27_10120 - - K - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
MILDBHCC_01756 2.56e-123 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
MILDBHCC_01757 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_01758 2.1e-183 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MILDBHCC_01759 3.82e-152 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MILDBHCC_01760 0.0 - - - M - - - family 8
MILDBHCC_01761 0.0 - - - M - - - family 8
MILDBHCC_01762 1.26e-289 - - - M - - - Pfam:DUF1792
MILDBHCC_01763 1.24e-99 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
MILDBHCC_01764 8.14e-40 - - - UW - - - Tetratricopeptide repeat
MILDBHCC_01765 7.73e-112 - - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MILDBHCC_01766 2.79e-299 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MILDBHCC_01767 1.34e-37 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MILDBHCC_01768 2.84e-243 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MILDBHCC_01769 8.33e-53 licB2 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MILDBHCC_01770 4.94e-15 - - - - - - - -
MILDBHCC_01771 7.75e-101 - - - - - - - -
MILDBHCC_01772 2.85e-166 - - - - - - - -
MILDBHCC_01774 8.48e-241 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MILDBHCC_01775 1.21e-152 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MILDBHCC_01776 2.53e-209 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MILDBHCC_01777 7.8e-266 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MILDBHCC_01778 6.4e-281 - - - KQ - - - helix_turn_helix, mercury resistance
MILDBHCC_01779 1.22e-06 - - - - - - - -
MILDBHCC_01782 2.03e-09 - - - - - - - -
MILDBHCC_01783 8.94e-161 - - - S - - - Rib/alpha-like repeat
MILDBHCC_01784 6.93e-88 - - - S - - - Domain of unknown function DUF1828
MILDBHCC_01785 1.48e-90 - - - - - - - -
MILDBHCC_01786 2.18e-91 - - - - - - - -
MILDBHCC_01787 4.42e-105 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MILDBHCC_01788 5.83e-172 - - - - - - - -
MILDBHCC_01790 1.46e-209 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Peptidase family M48
MILDBHCC_01791 1.45e-130 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
MILDBHCC_01792 5.79e-136 - - - - - - - -
MILDBHCC_01793 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MILDBHCC_01794 7.49e-208 - 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MILDBHCC_01795 2.27e-179 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MILDBHCC_01796 7.71e-186 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MILDBHCC_01797 1.27e-81 - - - - - - - -
MILDBHCC_01798 8.03e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MILDBHCC_01799 3.03e-257 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MILDBHCC_01800 2.08e-302 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MILDBHCC_01817 6.09e-81 - - - - - - - -
MILDBHCC_01829 1.91e-281 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
MILDBHCC_01830 3.5e-251 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MILDBHCC_01831 3.15e-232 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MILDBHCC_01832 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MILDBHCC_01833 3.2e-91 - - - O - - - OsmC-like protein
MILDBHCC_01834 0.0 - - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MILDBHCC_01835 6.12e-232 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MILDBHCC_01836 2.45e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MILDBHCC_01837 2.72e-208 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MILDBHCC_01838 2.97e-207 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MILDBHCC_01839 1.36e-100 ykuP - - C ko:K03839 - ko00000 Flavodoxin
MILDBHCC_01840 6.2e-114 gtcA1 - - S - - - Teichoic acid glycosylation protein
MILDBHCC_01841 1.05e-274 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MILDBHCC_01842 6.15e-40 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MILDBHCC_01843 1.2e-127 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
MILDBHCC_01845 1.09e-61 - - - S - - - Enterocin A Immunity
MILDBHCC_01846 3.44e-283 - - - S - - - CAAX protease self-immunity
MILDBHCC_01850 6.77e-71 - - - S - - - Enterocin A Immunity
MILDBHCC_01852 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
MILDBHCC_01853 4.71e-285 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
MILDBHCC_01854 1.89e-185 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MILDBHCC_01855 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MILDBHCC_01856 6.99e-136 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
MILDBHCC_01857 4.62e-31 - - - S - - - Bacteriocin class II with double-glycine leader peptide
MILDBHCC_01862 5.74e-208 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MILDBHCC_01863 4.87e-169 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MILDBHCC_01864 1.29e-172 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MILDBHCC_01865 1.75e-189 - - - K - - - Helix-turn-helix XRE-family like proteins
MILDBHCC_01866 7.76e-108 - - - - - - - -
MILDBHCC_01867 2.13e-313 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MILDBHCC_01868 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MILDBHCC_01873 0.0 mdr - - EGP - - - Major Facilitator
MILDBHCC_01874 6.76e-168 - - - S - - - membrane
MILDBHCC_01875 5.72e-104 - - - K - - - LytTr DNA-binding domain
MILDBHCC_01876 3.54e-67 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MILDBHCC_01877 9.68e-134 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MILDBHCC_01878 1.45e-150 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MILDBHCC_01879 4.94e-37 - - - L ko:K07483 - ko00000 transposase activity
MILDBHCC_01880 2.68e-131 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MILDBHCC_01881 5.14e-103 - - - S - - - Membrane

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)