ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
EFBHDGAE_00001 1.73e-247 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFBHDGAE_00002 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFBHDGAE_00003 6.56e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
EFBHDGAE_00004 7.14e-111 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EFBHDGAE_00006 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EFBHDGAE_00007 3.97e-60 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EFBHDGAE_00008 6.48e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EFBHDGAE_00009 2.06e-28 - - - S - - - Protein of unknown function (DUF2508)
EFBHDGAE_00010 9.81e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EFBHDGAE_00011 2.25e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
EFBHDGAE_00012 6.77e-247 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EFBHDGAE_00013 2.47e-74 yabA - - L - - - Involved in initiation control of chromosome replication
EFBHDGAE_00014 6.95e-203 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EFBHDGAE_00015 4.02e-189 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
EFBHDGAE_00016 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
EFBHDGAE_00017 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EFBHDGAE_00018 1.12e-219 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
EFBHDGAE_00019 8.55e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
EFBHDGAE_00020 2.34e-204 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
EFBHDGAE_00021 2.08e-239 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EFBHDGAE_00022 4.08e-218 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
EFBHDGAE_00023 1.15e-303 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
EFBHDGAE_00024 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
EFBHDGAE_00025 3.41e-281 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
EFBHDGAE_00026 1.61e-274 arcT - - E - - - Aminotransferase
EFBHDGAE_00027 1.68e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
EFBHDGAE_00028 1.93e-143 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
EFBHDGAE_00029 3.65e-250 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EFBHDGAE_00031 3.83e-100 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EFBHDGAE_00032 1.32e-97 - - - K - - - Transcriptional regulator, MarR family
EFBHDGAE_00033 7.59e-219 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EFBHDGAE_00034 4.18e-46 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EFBHDGAE_00035 1.86e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
EFBHDGAE_00036 2.19e-164 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
EFBHDGAE_00037 1.09e-290 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EFBHDGAE_00038 3.46e-94 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EFBHDGAE_00039 1.13e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EFBHDGAE_00040 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
EFBHDGAE_00041 7.54e-205 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EFBHDGAE_00042 2.69e-181 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
EFBHDGAE_00043 6.3e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
EFBHDGAE_00044 1.67e-117 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
EFBHDGAE_00045 1.04e-224 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EFBHDGAE_00046 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
EFBHDGAE_00047 9.4e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EFBHDGAE_00048 9.49e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EFBHDGAE_00049 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EFBHDGAE_00050 0.0 ydaO - - E - - - amino acid
EFBHDGAE_00051 1.68e-49 - - - - - - - -
EFBHDGAE_00052 6.92e-148 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
EFBHDGAE_00053 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
EFBHDGAE_00054 8.76e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
EFBHDGAE_00055 4.64e-124 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EFBHDGAE_00056 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EFBHDGAE_00057 1.24e-258 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EFBHDGAE_00058 1.97e-70 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
EFBHDGAE_00059 4.15e-69 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
EFBHDGAE_00060 4.82e-227 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EFBHDGAE_00061 1.94e-211 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EFBHDGAE_00062 9.09e-236 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
EFBHDGAE_00063 7.64e-220 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EFBHDGAE_00064 1.06e-188 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
EFBHDGAE_00065 1.08e-289 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EFBHDGAE_00066 6.21e-241 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EFBHDGAE_00067 4.01e-104 yphH - - S - - - Cupin domain
EFBHDGAE_00068 8.22e-167 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EFBHDGAE_00069 3.44e-200 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
EFBHDGAE_00070 4.22e-215 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EFBHDGAE_00071 3.96e-253 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EFBHDGAE_00072 2.76e-218 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EFBHDGAE_00073 1.07e-178 - - - S - - - haloacid dehalogenase-like hydrolase
EFBHDGAE_00074 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EFBHDGAE_00075 5.06e-145 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
EFBHDGAE_00077 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EFBHDGAE_00078 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EFBHDGAE_00079 6.18e-262 - - - - - - - -
EFBHDGAE_00080 1.35e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
EFBHDGAE_00081 2e-240 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
EFBHDGAE_00082 6.71e-214 whiA - - K ko:K09762 - ko00000 May be required for sporulation
EFBHDGAE_00083 8.91e-19 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
EFBHDGAE_00085 4.88e-236 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
EFBHDGAE_00086 9.97e-103 - - - F - - - Nucleoside 2-deoxyribosyltransferase
EFBHDGAE_00087 4.52e-126 - - - - - - - -
EFBHDGAE_00089 2.94e-156 int2 - - L - - - Belongs to the 'phage' integrase family
EFBHDGAE_00090 7.1e-43 - - - - - - - -
EFBHDGAE_00093 4.58e-40 - - - E - - - Zn peptidase
EFBHDGAE_00094 4.48e-148 - - - V - - - Abi-like protein
EFBHDGAE_00095 3.06e-25 - 3.4.21.88 - KT ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Peptidase S24-like
EFBHDGAE_00096 1.08e-19 - - - K - - - sequence-specific DNA binding
EFBHDGAE_00101 2.14e-54 - - - S - - - Siphovirus Gp157
EFBHDGAE_00102 3.15e-165 - - - L - - - Helicase C-terminal domain protein
EFBHDGAE_00103 7.13e-107 - - - L - - - AAA domain
EFBHDGAE_00104 1.6e-38 - - - - - - - -
EFBHDGAE_00105 2.07e-103 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
EFBHDGAE_00106 3.17e-138 - - - S ko:K06919 - ko00000 Virulence-associated protein E
EFBHDGAE_00111 7.55e-05 - - - S - - - Protein of unknwon function (DUF3310)
EFBHDGAE_00113 3.07e-78 - - - S - - - Phage transcriptional regulator, ArpU family
EFBHDGAE_00115 2.04e-71 - - - L ko:K07474 - ko00000 Terminase small subunit
EFBHDGAE_00117 3.06e-207 yqaT - - S ko:K06909 - ko00000 Phage terminase, large subunit
EFBHDGAE_00118 3.28e-261 - - - S - - - Phage portal protein, SPP1 Gp6-like
EFBHDGAE_00119 1.03e-173 - - - S - - - Phage Mu protein F like protein
EFBHDGAE_00121 5.7e-86 - - - S - - - aminoacyl-tRNA ligase activity
EFBHDGAE_00122 1.57e-153 - - - - - - - -
EFBHDGAE_00123 2.08e-64 - - - S - - - Phage gp6-like head-tail connector protein
EFBHDGAE_00124 2.92e-55 - - - S - - - exonuclease activity
EFBHDGAE_00125 6.25e-57 - - - - - - - -
EFBHDGAE_00126 3.25e-107 - - - S - - - Phage major tail protein 2
EFBHDGAE_00127 1.42e-50 - - - S - - - Pfam:Phage_TAC_12
EFBHDGAE_00128 5.75e-249 - - - S - - - peptidoglycan catabolic process
EFBHDGAE_00130 2.63e-285 - - - S - - - peptidoglycan catabolic process
EFBHDGAE_00135 8.81e-14 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
EFBHDGAE_00136 1.1e-08 - - - - - - - -
EFBHDGAE_00137 3.02e-16 - - - S - - - Phage minor structural protein
EFBHDGAE_00138 3.02e-140 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
EFBHDGAE_00139 6.91e-73 - - - L ko:K07497 - ko00000 hmm pf00665
EFBHDGAE_00140 6.33e-133 - - - - - - - -
EFBHDGAE_00142 4.27e-135 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
EFBHDGAE_00144 2.89e-110 - - - K - - - GNAT family
EFBHDGAE_00145 2.47e-156 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
EFBHDGAE_00146 9.18e-206 yvgN - - S - - - Aldo keto reductase
EFBHDGAE_00147 5.46e-186 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EFBHDGAE_00148 4.49e-169 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
EFBHDGAE_00150 1.55e-74 - - - - - - - -
EFBHDGAE_00152 3.63e-14 - - - - - - - -
EFBHDGAE_00153 1.02e-102 - - - K - - - Winged helix-turn-helix DNA-binding
EFBHDGAE_00154 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_00155 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
EFBHDGAE_00156 3.76e-245 ampC - - V - - - Beta-lactamase
EFBHDGAE_00157 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EFBHDGAE_00158 9.42e-63 - - - - - - - -
EFBHDGAE_00159 7.49e-181 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
EFBHDGAE_00160 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
EFBHDGAE_00161 1.78e-139 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
EFBHDGAE_00162 5.36e-208 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EFBHDGAE_00163 1.92e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EFBHDGAE_00164 2.77e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EFBHDGAE_00165 9e-294 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EFBHDGAE_00166 3.86e-149 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EFBHDGAE_00167 8.52e-254 yibE - - S - - - overlaps another CDS with the same product name
EFBHDGAE_00168 1.35e-165 yibF - - S - - - overlaps another CDS with the same product name
EFBHDGAE_00169 1.1e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
EFBHDGAE_00170 5.66e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
EFBHDGAE_00171 2.13e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EFBHDGAE_00172 3.92e-80 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EFBHDGAE_00173 1.23e-119 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EFBHDGAE_00174 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EFBHDGAE_00175 2.53e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EFBHDGAE_00176 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EFBHDGAE_00177 1.19e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
EFBHDGAE_00178 8.07e-40 - - - S - - - Protein of unknown function (DUF1146)
EFBHDGAE_00179 2.4e-278 - - - M - - - EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
EFBHDGAE_00180 9.42e-234 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
EFBHDGAE_00181 7.67e-43 - - - S - - - Protein of unknown function (DUF2969)
EFBHDGAE_00182 1.03e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
EFBHDGAE_00184 9.42e-232 - - - S - - - Protein of unknown function (DUF2785)
EFBHDGAE_00185 2.38e-274 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
EFBHDGAE_00186 3.48e-40 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
EFBHDGAE_00187 6.67e-121 - - - L ko:K07497 - ko00000 hmm pf00665
EFBHDGAE_00189 1.03e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
EFBHDGAE_00190 1.9e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EFBHDGAE_00191 6.93e-281 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EFBHDGAE_00192 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EFBHDGAE_00193 5.61e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EFBHDGAE_00194 1.29e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EFBHDGAE_00195 6.83e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
EFBHDGAE_00196 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
EFBHDGAE_00197 3.08e-211 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EFBHDGAE_00198 1.1e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
EFBHDGAE_00199 4.7e-163 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
EFBHDGAE_00200 1e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
EFBHDGAE_00201 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
EFBHDGAE_00202 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
EFBHDGAE_00203 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EFBHDGAE_00204 2.2e-215 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EFBHDGAE_00205 1.65e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EFBHDGAE_00206 1.98e-166 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EFBHDGAE_00207 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
EFBHDGAE_00208 3.27e-288 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EFBHDGAE_00209 1.72e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EFBHDGAE_00210 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EFBHDGAE_00212 2.44e-138 - - - - - - - -
EFBHDGAE_00213 7.18e-170 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
EFBHDGAE_00214 3.3e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
EFBHDGAE_00215 1.95e-195 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
EFBHDGAE_00216 1.74e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
EFBHDGAE_00217 1.28e-176 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EFBHDGAE_00218 2.78e-158 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
EFBHDGAE_00219 4.94e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
EFBHDGAE_00220 9.17e-54 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
EFBHDGAE_00221 1.52e-114 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EFBHDGAE_00222 2.22e-182 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
EFBHDGAE_00223 0.0 - - - E ko:K03294 - ko00000 Amino Acid
EFBHDGAE_00224 6.59e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EFBHDGAE_00226 1.04e-05 csd1 3.5.1.28 - M ko:K01447,ko:K17733,ko:K19117 - ko00000,ko01000,ko01002,ko01011,ko02048 N-Acetylmuramoyl-L-alanine amidase
EFBHDGAE_00227 3.46e-225 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
EFBHDGAE_00228 1.75e-151 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_00229 8.85e-133 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
EFBHDGAE_00230 2.45e-56 - - - S - - - SEFIR domain
EFBHDGAE_00231 1.15e-20 - - - L - - - MULE transposase domain
EFBHDGAE_00232 1.72e-08 - - - - - - - -
EFBHDGAE_00233 3.2e-306 yeeA - - V - - - Type II restriction enzyme, methylase subunits
EFBHDGAE_00235 0.0 dld 1.1.5.12 - C ko:K03777 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-lactate dehydrogenase, membrane binding
EFBHDGAE_00236 4.33e-186 - - - L - - - 4.5 Transposon and IS
EFBHDGAE_00237 1.02e-159 - - - S - - - Membrane
EFBHDGAE_00238 6.42e-299 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EFBHDGAE_00239 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
EFBHDGAE_00240 5.86e-230 - - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
EFBHDGAE_00241 6.61e-181 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFBHDGAE_00242 5.3e-104 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
EFBHDGAE_00243 7.74e-105 usp5 - - T - - - universal stress protein
EFBHDGAE_00244 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EFBHDGAE_00245 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EFBHDGAE_00246 1.47e-265 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
EFBHDGAE_00247 8.99e-99 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
EFBHDGAE_00248 3.05e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
EFBHDGAE_00249 0.0 yhdP - - S - - - Transporter associated domain
EFBHDGAE_00250 1.14e-114 - - - GM - - - epimerase
EFBHDGAE_00251 1.7e-112 - - - K - - - Domain of unknown function (DUF1836)
EFBHDGAE_00252 3.73e-199 - - - G - - - Xylose isomerase domain protein TIM barrel
EFBHDGAE_00253 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EFBHDGAE_00254 3.78e-167 - - - - - - - -
EFBHDGAE_00255 4.23e-115 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EFBHDGAE_00256 5.2e-167 gntR - - K - - - UbiC transcription regulator-associated domain protein
EFBHDGAE_00257 4.33e-191 - - - S - - - haloacid dehalogenase-like hydrolase
EFBHDGAE_00258 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
EFBHDGAE_00260 9.08e-80 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EFBHDGAE_00261 0.0 FbpA - - K - - - Fibronectin-binding protein
EFBHDGAE_00262 2.83e-205 - - - S - - - EDD domain protein, DegV family
EFBHDGAE_00263 3.26e-128 - - - - - - - -
EFBHDGAE_00264 1.23e-172 yaaA - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
EFBHDGAE_00265 1.76e-153 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
EFBHDGAE_00266 9.43e-45 ylbE - - GM - - - NAD(P)H-binding
EFBHDGAE_00267 2.01e-80 ylbE - - GM - - - NAD(P)H-binding
EFBHDGAE_00268 8.44e-128 - - - K - - - Acetyltransferase (GNAT) domain
EFBHDGAE_00269 4.02e-202 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EFBHDGAE_00270 4.34e-299 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
EFBHDGAE_00271 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
EFBHDGAE_00272 2.59e-153 azlC - - E - - - azaleucine resistance protein AzlC
EFBHDGAE_00273 7.76e-72 azlD - - E - - - Branched-chain amino acid transport
EFBHDGAE_00274 1.16e-72 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
EFBHDGAE_00275 4.9e-232 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
EFBHDGAE_00276 2.59e-229 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
EFBHDGAE_00277 2.87e-274 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EFBHDGAE_00278 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
EFBHDGAE_00279 2.03e-249 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
EFBHDGAE_00280 2.47e-274 - - - E - - - GDSL-like Lipase/Acylhydrolase family
EFBHDGAE_00281 6.67e-123 rlrB - - K - - - LysR substrate binding domain protein
EFBHDGAE_00282 3.26e-15 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
EFBHDGAE_00283 0.0 yhdP - - S - - - Transporter associated domain
EFBHDGAE_00284 1.77e-251 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
EFBHDGAE_00285 6.78e-199 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
EFBHDGAE_00286 1.53e-214 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
EFBHDGAE_00287 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EFBHDGAE_00288 2.36e-304 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EFBHDGAE_00289 8.43e-206 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
EFBHDGAE_00290 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EFBHDGAE_00291 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
EFBHDGAE_00292 2.69e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
EFBHDGAE_00293 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EFBHDGAE_00295 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
EFBHDGAE_00296 7.21e-108 - - - S - - - Domain of unknown function (DUF4352)
EFBHDGAE_00297 3.5e-145 yicL - - EG - - - EamA-like transporter family
EFBHDGAE_00298 3.76e-84 - - - - - - - -
EFBHDGAE_00301 5.89e-44 - - - - - - - -
EFBHDGAE_00302 5.63e-89 - - - S - - - pyridoxamine 5-phosphate
EFBHDGAE_00303 5.37e-230 - - - K - - - WYL domain
EFBHDGAE_00304 4.66e-312 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
EFBHDGAE_00305 6.72e-53 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
EFBHDGAE_00306 4.75e-214 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EFBHDGAE_00307 2.77e-270 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EFBHDGAE_00308 5.08e-263 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
EFBHDGAE_00309 2.14e-278 - - - G - - - Transporter, major facilitator family protein
EFBHDGAE_00310 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EFBHDGAE_00311 1.2e-201 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EFBHDGAE_00312 2.61e-83 yuxO - - Q - - - Thioesterase superfamily
EFBHDGAE_00313 6.46e-49 citG 2.4.2.52, 2.7.7.61 - HI ko:K05964,ko:K13927 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
EFBHDGAE_00314 7.39e-20 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
EFBHDGAE_00315 4.12e-06 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
EFBHDGAE_00316 2.63e-31 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
EFBHDGAE_00317 7.01e-32 - - - I - - - Alpha/beta hydrolase family
EFBHDGAE_00318 5.73e-41 - - - I - - - Alpha/beta hydrolase family
EFBHDGAE_00319 3.46e-52 - - - L - - - Transposase and inactivated derivatives IS30 family
EFBHDGAE_00321 2.01e-55 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EFBHDGAE_00323 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
EFBHDGAE_00324 4.03e-35 XK27_02560 - - S - - - Pfam:DUF59
EFBHDGAE_00325 2.84e-167 yocS - - S ko:K03453 - ko00000 Transporter
EFBHDGAE_00326 7.97e-308 - - - EGP ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
EFBHDGAE_00327 1.81e-252 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EFBHDGAE_00328 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EFBHDGAE_00329 3.63e-141 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EFBHDGAE_00330 2.61e-188 XK27_00020 - - J - - - Telomere recombination
EFBHDGAE_00331 3.39e-06 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
EFBHDGAE_00332 8.91e-80 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
EFBHDGAE_00333 0.000602 - - - G - - - COG2513 PEP phosphonomutase and related enzymes
EFBHDGAE_00334 8.68e-15 - - - EGP ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
EFBHDGAE_00335 2.34e-103 - - - G ko:K08368,ko:K08369 - ko00000,ko02000 Major Facilitator
EFBHDGAE_00336 9.66e-07 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
EFBHDGAE_00337 1.62e-73 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EFBHDGAE_00338 1.66e-38 - - - IQ - - - oxidoreductase activity
EFBHDGAE_00339 4e-67 - - - C - - - Flavodoxin
EFBHDGAE_00340 4.14e-202 yicL - - EG - - - EamA-like transporter family
EFBHDGAE_00341 1.26e-137 - - - L - - - Integrase
EFBHDGAE_00342 4.58e-59 - - - K - - - transcriptional regulator
EFBHDGAE_00343 9.24e-151 - - - S - - - membrane
EFBHDGAE_00344 5.5e-141 - - - S - - - VIT family
EFBHDGAE_00345 2.49e-110 - - - T - - - Belongs to the universal stress protein A family
EFBHDGAE_00346 1.18e-28 elaA - - S ko:K02348 - ko00000 acyltransferase COG2153
EFBHDGAE_00347 8.89e-282 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
EFBHDGAE_00348 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EFBHDGAE_00349 1.15e-77 - - - - - - - -
EFBHDGAE_00350 3.98e-96 - - - K - - - MerR HTH family regulatory protein
EFBHDGAE_00351 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
EFBHDGAE_00352 2.34e-150 - - - S - - - Domain of unknown function (DUF4811)
EFBHDGAE_00353 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
EFBHDGAE_00354 3.84e-315 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EFBHDGAE_00355 8.41e-260 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
EFBHDGAE_00356 1.91e-178 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
EFBHDGAE_00357 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
EFBHDGAE_00358 8.23e-215 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EFBHDGAE_00360 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EFBHDGAE_00361 2.87e-138 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
EFBHDGAE_00362 1.92e-241 - - - I - - - Alpha beta
EFBHDGAE_00363 3.44e-155 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
EFBHDGAE_00364 0.0 - - - S - - - Putative threonine/serine exporter
EFBHDGAE_00365 7.22e-206 mleR2 - - K - - - LysR family transcriptional regulator
EFBHDGAE_00366 1.18e-286 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
EFBHDGAE_00367 1.58e-270 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
EFBHDGAE_00368 3.78e-282 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EFBHDGAE_00369 2.48e-117 - - - S - - - NADPH-dependent FMN reductase
EFBHDGAE_00370 2.47e-234 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
EFBHDGAE_00371 1.08e-289 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
EFBHDGAE_00372 1.12e-98 mleR - - K - - - LysR family
EFBHDGAE_00373 4e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EFBHDGAE_00374 7.86e-77 XK27_04120 - - S - - - Putative amino acid metabolism
EFBHDGAE_00375 3.96e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EFBHDGAE_00376 9.41e-09 - - - - - - - -
EFBHDGAE_00377 1.28e-126 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
EFBHDGAE_00378 9.99e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
EFBHDGAE_00379 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EFBHDGAE_00381 6.19e-143 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
EFBHDGAE_00382 1.24e-186 ylmH - - S - - - S4 domain protein
EFBHDGAE_00383 7.27e-56 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
EFBHDGAE_00384 1.5e-101 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EFBHDGAE_00385 9.01e-294 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EFBHDGAE_00386 4.88e-300 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EFBHDGAE_00387 5.43e-193 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EFBHDGAE_00388 2.06e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EFBHDGAE_00389 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EFBHDGAE_00390 4.46e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EFBHDGAE_00391 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EFBHDGAE_00392 5.28e-31 ftsL - - D - - - Cell division protein FtsL
EFBHDGAE_00393 5.37e-221 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EFBHDGAE_00394 8.95e-103 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
EFBHDGAE_00395 1.98e-75 - - - - - - - -
EFBHDGAE_00396 4.5e-12 - - - S - - - Protein of unknown function (DUF4044)
EFBHDGAE_00397 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EFBHDGAE_00398 2.01e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EFBHDGAE_00399 3.9e-208 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
EFBHDGAE_00400 1.09e-250 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
EFBHDGAE_00401 5.39e-221 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EFBHDGAE_00402 9.49e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EFBHDGAE_00403 5.24e-159 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
EFBHDGAE_00404 1.46e-147 yjbH - - Q - - - Thioredoxin
EFBHDGAE_00405 2.06e-263 coiA - - S ko:K06198 - ko00000 Competence protein
EFBHDGAE_00406 3.59e-151 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EFBHDGAE_00407 1.12e-90 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EFBHDGAE_00428 4.93e-80 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
EFBHDGAE_00429 4.59e-238 - - - D - - - nuclear chromosome segregation
EFBHDGAE_00430 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
EFBHDGAE_00431 6.49e-210 - - - S - - - Calcineurin-like phosphoesterase
EFBHDGAE_00434 1.15e-149 - - - - - - - -
EFBHDGAE_00435 1.56e-170 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
EFBHDGAE_00436 8.7e-166 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
EFBHDGAE_00437 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EFBHDGAE_00438 4.68e-196 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EFBHDGAE_00439 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
EFBHDGAE_00440 9.91e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
EFBHDGAE_00442 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
EFBHDGAE_00443 7.85e-242 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
EFBHDGAE_00444 4.35e-213 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
EFBHDGAE_00445 7.78e-165 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EFBHDGAE_00446 2.18e-213 - - - I - - - alpha/beta hydrolase fold
EFBHDGAE_00447 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
EFBHDGAE_00448 8.06e-134 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
EFBHDGAE_00449 2.49e-158 - 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EFBHDGAE_00450 6.52e-73 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
EFBHDGAE_00451 5.89e-126 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
EFBHDGAE_00452 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EFBHDGAE_00453 2.73e-264 yacL - - S - - - domain protein
EFBHDGAE_00454 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EFBHDGAE_00455 9.63e-130 ywlG - - S - - - Belongs to the UPF0340 family
EFBHDGAE_00456 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EFBHDGAE_00457 1.25e-93 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EFBHDGAE_00458 2.04e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EFBHDGAE_00459 3.23e-134 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
EFBHDGAE_00460 5.85e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EFBHDGAE_00461 2.48e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EFBHDGAE_00462 4.83e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
EFBHDGAE_00463 3.34e-68 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EFBHDGAE_00464 1.68e-157 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EFBHDGAE_00465 4.74e-51 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
EFBHDGAE_00466 3.03e-96 - - - O ko:K07397 - ko00000 OsmC-like protein
EFBHDGAE_00467 2.96e-100 ywnA - - K - - - Transcriptional regulator
EFBHDGAE_00468 5.73e-209 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
EFBHDGAE_00469 3.63e-138 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EFBHDGAE_00470 1.62e-181 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_00471 7.95e-132 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
EFBHDGAE_00472 5.66e-230 - - - C - - - Zinc-binding dehydrogenase
EFBHDGAE_00473 3.37e-249 bdhA 1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4 - C ko:K00004,ko:K00008,ko:K00098 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
EFBHDGAE_00474 1.21e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
EFBHDGAE_00475 6.88e-230 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EFBHDGAE_00476 7.19e-260 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
EFBHDGAE_00477 1e-76 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
EFBHDGAE_00478 1.51e-282 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate/isopropylmalate dehydrogenase
EFBHDGAE_00479 1.23e-191 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
EFBHDGAE_00480 1.85e-105 - - - S - - - ECF-type riboflavin transporter, S component
EFBHDGAE_00481 1.14e-213 yvgN - - C - - - Aldo keto reductase
EFBHDGAE_00482 7.18e-207 - - - S - - - DUF218 domain
EFBHDGAE_00484 1.41e-06 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
EFBHDGAE_00485 7.5e-122 - 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
EFBHDGAE_00486 8.64e-208 - - - I - - - alpha/beta hydrolase fold
EFBHDGAE_00487 4.74e-159 - - - S - - - Phage minor capsid protein 2
EFBHDGAE_00490 1.71e-268 - - - E - - - Aminotransferase
EFBHDGAE_00491 8.61e-104 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
EFBHDGAE_00492 2.71e-157 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
EFBHDGAE_00493 2.36e-22 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
EFBHDGAE_00494 7.65e-60 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
EFBHDGAE_00495 5.43e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EFBHDGAE_00496 0.0 - - - E ko:K03758 - ko00000,ko02000 Amino acid permease
EFBHDGAE_00497 3.55e-154 - - - M - - - racemase activity, acting on amino acids and derivatives
EFBHDGAE_00498 6.4e-197 - - - C - - - NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
EFBHDGAE_00499 2.52e-153 eriC - - P ko:K03281 - ko00000 chloride
EFBHDGAE_00500 8.72e-80 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EFBHDGAE_00501 4.95e-216 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EFBHDGAE_00502 3.04e-233 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EFBHDGAE_00503 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EFBHDGAE_00504 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EFBHDGAE_00505 3.5e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EFBHDGAE_00506 1.15e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EFBHDGAE_00507 6.31e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EFBHDGAE_00508 4.65e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EFBHDGAE_00509 1.19e-278 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EFBHDGAE_00510 1.28e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EFBHDGAE_00511 2.9e-294 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
EFBHDGAE_00512 1.68e-154 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
EFBHDGAE_00513 8.01e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
EFBHDGAE_00514 9.89e-201 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EFBHDGAE_00515 1.02e-300 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
EFBHDGAE_00517 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
EFBHDGAE_00518 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
EFBHDGAE_00519 6.26e-215 yitL - - S ko:K00243 - ko00000 S1 domain
EFBHDGAE_00520 2.98e-175 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
EFBHDGAE_00521 5.26e-88 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFBHDGAE_00522 1.18e-182 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EFBHDGAE_00523 1.3e-130 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EFBHDGAE_00524 2.38e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EFBHDGAE_00525 8.28e-112 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EFBHDGAE_00526 1.34e-254 - - - S - - - Helix-turn-helix domain
EFBHDGAE_00527 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
EFBHDGAE_00528 4.37e-76 - - - M - - - Lysin motif
EFBHDGAE_00529 2.29e-153 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
EFBHDGAE_00530 1.88e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
EFBHDGAE_00531 1.5e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
EFBHDGAE_00532 2.65e-53 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EFBHDGAE_00533 1.02e-299 XK27_05225 - - S - - - Tetratricopeptide repeat protein
EFBHDGAE_00534 1.06e-210 - - - L - - - Phage integrase, N-terminal SAM-like domain
EFBHDGAE_00535 6.2e-284 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EFBHDGAE_00536 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_00537 5.32e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EFBHDGAE_00538 4.4e-122 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EFBHDGAE_00539 4.66e-140 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
EFBHDGAE_00540 9.07e-196 WQ51_01275 - - S - - - EDD domain protein, DegV family
EFBHDGAE_00541 1.04e-269 - 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase
EFBHDGAE_00542 9.86e-146 cat 2.3.1.79 - S ko:K00661,ko:K18234 - ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
EFBHDGAE_00543 3.34e-215 - - - E - - - lipolytic protein G-D-S-L family
EFBHDGAE_00544 2.85e-135 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
EFBHDGAE_00545 2.1e-49 yozE - - S - - - Belongs to the UPF0346 family
EFBHDGAE_00546 7.25e-207 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EFBHDGAE_00547 8.69e-182 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EFBHDGAE_00548 6.25e-213 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
EFBHDGAE_00549 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EFBHDGAE_00550 1.92e-199 - - - D - - - DNA integration
EFBHDGAE_00551 2.67e-219 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
EFBHDGAE_00552 5.26e-134 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EFBHDGAE_00553 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EFBHDGAE_00554 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EFBHDGAE_00555 2.53e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
EFBHDGAE_00556 3.78e-219 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
EFBHDGAE_00557 7.86e-92 - - - S - - - Belongs to the HesB IscA family
EFBHDGAE_00558 4.65e-100 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
EFBHDGAE_00559 8.5e-121 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
EFBHDGAE_00560 5.48e-106 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
EFBHDGAE_00561 1.69e-312 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
EFBHDGAE_00562 1.07e-306 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
EFBHDGAE_00563 0.0 - - - EP - - - Psort location Cytoplasmic, score
EFBHDGAE_00565 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
EFBHDGAE_00566 2.2e-151 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
EFBHDGAE_00567 3.53e-311 yhjX - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
EFBHDGAE_00569 9.31e-08 - - - S - - - Domain of unknown function (DUF4190)
EFBHDGAE_00570 2.27e-77 - - - L ko:K07497 - ko00000 hmm pf00665
EFBHDGAE_00571 4.99e-78 - - - C - - - FMN binding
EFBHDGAE_00572 1.98e-258 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EFBHDGAE_00573 9.14e-139 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
EFBHDGAE_00574 5.57e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
EFBHDGAE_00575 1.97e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EFBHDGAE_00576 9.59e-104 - - - K - - - 2 iron, 2 sulfur cluster binding
EFBHDGAE_00577 0.0 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
EFBHDGAE_00578 8.79e-284 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFBHDGAE_00579 5.06e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EFBHDGAE_00580 4.7e-102 - - - C - - - aldo keto reductase
EFBHDGAE_00581 1.65e-22 - - - C - - - aldo keto reductase
EFBHDGAE_00582 3.72e-145 pgm1 - - G - - - phosphoglycerate mutase
EFBHDGAE_00584 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EFBHDGAE_00585 6.35e-255 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EFBHDGAE_00586 2.63e-69 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
EFBHDGAE_00587 7.56e-73 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EFBHDGAE_00588 5.43e-183 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EFBHDGAE_00589 3.39e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EFBHDGAE_00590 3.46e-143 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EFBHDGAE_00591 1.08e-133 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
EFBHDGAE_00592 5.2e-292 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EFBHDGAE_00593 3.18e-140 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EFBHDGAE_00594 2.49e-276 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EFBHDGAE_00595 1.73e-213 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
EFBHDGAE_00596 4.37e-61 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EFBHDGAE_00597 2.15e-11 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EFBHDGAE_00598 1.46e-71 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EFBHDGAE_00599 4.05e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EFBHDGAE_00600 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
EFBHDGAE_00601 3.09e-90 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EFBHDGAE_00602 5.73e-243 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EFBHDGAE_00603 3.87e-80 - - - - - - - -
EFBHDGAE_00604 6.19e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EFBHDGAE_00605 5.85e-169 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EFBHDGAE_00606 8.04e-124 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EFBHDGAE_00607 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EFBHDGAE_00608 9.69e-317 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EFBHDGAE_00609 2.81e-212 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EFBHDGAE_00610 1.58e-122 - - - K - - - transcriptional regulator
EFBHDGAE_00611 6.55e-166 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
EFBHDGAE_00612 1.24e-241 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
EFBHDGAE_00613 5.02e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
EFBHDGAE_00614 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
EFBHDGAE_00615 5.13e-210 - - - C - - - Aldo keto reductase
EFBHDGAE_00616 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
EFBHDGAE_00617 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
EFBHDGAE_00618 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EFBHDGAE_00619 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
EFBHDGAE_00620 4.71e-47 - - - - - - - -
EFBHDGAE_00621 3.41e-278 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EFBHDGAE_00622 1.39e-231 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFBHDGAE_00623 1.34e-233 - - - D ko:K06889 - ko00000 Alpha beta
EFBHDGAE_00624 1.47e-244 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EFBHDGAE_00625 4.98e-20 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_00626 6.67e-42 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
EFBHDGAE_00628 4.08e-309 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
EFBHDGAE_00629 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
EFBHDGAE_00630 3.77e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EFBHDGAE_00631 4.8e-251 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
EFBHDGAE_00632 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EFBHDGAE_00633 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFBHDGAE_00634 4e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFBHDGAE_00635 1.36e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFBHDGAE_00636 6.13e-174 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
EFBHDGAE_00637 1.3e-25 - - - K - - - HxlR-like helix-turn-helix
EFBHDGAE_00638 1.48e-21 - - - IQ - - - Dehydrogenase
EFBHDGAE_00639 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
EFBHDGAE_00640 1.19e-222 hrpQ 4.6.1.1 - T ko:K01768,ko:K03220,ko:K10914 ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111 ko00000,ko00001,ko00002,ko01000,ko02044,ko03000 histone H2A K63-linked ubiquitination
EFBHDGAE_00641 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EFBHDGAE_00642 4.12e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EFBHDGAE_00643 1.17e-105 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EFBHDGAE_00644 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
EFBHDGAE_00645 9.91e-224 ydbI - - K - - - AI-2E family transporter
EFBHDGAE_00646 2.92e-05 - - - K - - - Transcriptional regulator C-terminal region
EFBHDGAE_00647 8.59e-293 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
EFBHDGAE_00648 4.46e-129 - - - S ko:K07002 - ko00000 Serine hydrolase
EFBHDGAE_00649 4.35e-79 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
EFBHDGAE_00650 8.39e-56 - - - K - - - prlF antitoxin for toxin YhaV_toxin
EFBHDGAE_00651 4.49e-78 - - - S - - - branched-chain amino acid
EFBHDGAE_00652 1.04e-188 - - - E - - - AzlC protein
EFBHDGAE_00653 2.28e-267 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EFBHDGAE_00654 7.59e-268 hpk31 - - T - - - Histidine kinase
EFBHDGAE_00655 2.49e-157 vanR - - K - - - response regulator
EFBHDGAE_00656 3.21e-120 - - - S ko:K09705 - ko00000 Cupin superfamily (DUF985)
EFBHDGAE_00657 4.95e-215 - - - K - - - LysR substrate binding domain
EFBHDGAE_00658 6.96e-222 - - - S - - - Conserved hypothetical protein 698
EFBHDGAE_00659 5.71e-107 lytE - - M - - - Lysin motif
EFBHDGAE_00660 6.1e-193 XK27_02985 - - S - - - Sucrose-6F-phosphate phosphohydrolase
EFBHDGAE_00661 8.27e-263 oatA - - I - - - Acyltransferase
EFBHDGAE_00662 4.4e-69 - - - - - - - -
EFBHDGAE_00663 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EFBHDGAE_00664 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EFBHDGAE_00665 3.41e-151 ybbR - - S - - - YbbR-like protein
EFBHDGAE_00666 1.61e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EFBHDGAE_00667 2.34e-212 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
EFBHDGAE_00668 4e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EFBHDGAE_00669 5.51e-118 - - - K - - - Acetyltransferase (GNAT) domain
EFBHDGAE_00670 4.21e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
EFBHDGAE_00671 9.74e-229 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
EFBHDGAE_00672 4.52e-175 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EFBHDGAE_00673 1.66e-139 - - - - - - - -
EFBHDGAE_00674 4.66e-110 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EFBHDGAE_00675 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EFBHDGAE_00676 6.82e-46 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
EFBHDGAE_00677 0.0 eriC - - P ko:K03281 - ko00000 chloride
EFBHDGAE_00678 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
EFBHDGAE_00679 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EFBHDGAE_00680 2.92e-184 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EFBHDGAE_00681 4.22e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
EFBHDGAE_00682 1.31e-244 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EFBHDGAE_00683 3.82e-23 - - - - - - - -
EFBHDGAE_00684 4.74e-23 - - - - - - - -
EFBHDGAE_00685 1.19e-41 - - - S - - - Transglycosylase associated protein
EFBHDGAE_00686 3.37e-96 asp1 - - S - - - Asp23 family, cell envelope-related function
EFBHDGAE_00687 3.87e-114 - - - - - - - -
EFBHDGAE_00688 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
EFBHDGAE_00689 3.59e-149 - - - L - - - Integrase core domain
EFBHDGAE_00690 1.21e-264 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EFBHDGAE_00691 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EFBHDGAE_00692 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
EFBHDGAE_00693 1.03e-239 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
EFBHDGAE_00694 8.43e-197 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
EFBHDGAE_00695 8.91e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EFBHDGAE_00696 7.64e-88 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
EFBHDGAE_00697 2.05e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EFBHDGAE_00698 1.75e-228 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
EFBHDGAE_00699 1.52e-93 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
EFBHDGAE_00700 3.81e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
EFBHDGAE_00701 1.1e-165 - - - F - - - glutamine amidotransferase
EFBHDGAE_00702 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EFBHDGAE_00703 1.39e-314 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
EFBHDGAE_00704 4.43e-250 - 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
EFBHDGAE_00705 3.81e-227 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
EFBHDGAE_00706 1.31e-215 - - - G - - - Phosphotransferase enzyme family
EFBHDGAE_00707 7.95e-221 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
EFBHDGAE_00708 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EFBHDGAE_00709 2.34e-204 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
EFBHDGAE_00710 3.21e-268 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
EFBHDGAE_00711 2.12e-87 - - - IQ - - - KR domain
EFBHDGAE_00712 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EFBHDGAE_00713 3.3e-260 yhdG - - E ko:K03294 - ko00000 Amino Acid
EFBHDGAE_00714 1.28e-94 - - - F - - - Nudix hydrolase
EFBHDGAE_00715 9.61e-137 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
EFBHDGAE_00716 7.28e-110 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
EFBHDGAE_00717 3.58e-10 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
EFBHDGAE_00718 8.3e-205 - - - - - - - -
EFBHDGAE_00719 1.96e-251 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
EFBHDGAE_00720 4.23e-122 - - - K - - - Transcriptional regulator (TetR family)
EFBHDGAE_00721 1.11e-276 yhgE - - V ko:K01421 - ko00000 domain protein
EFBHDGAE_00722 4.4e-112 - - - K - - - FR47-like protein
EFBHDGAE_00723 0.0 - - - E - - - amino acid
EFBHDGAE_00724 4.15e-172 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
EFBHDGAE_00725 6.22e-266 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EFBHDGAE_00726 2.06e-297 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EFBHDGAE_00727 1.58e-154 pgm3 - - G - - - phosphoglycerate mutase
EFBHDGAE_00728 1.45e-152 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
EFBHDGAE_00729 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EFBHDGAE_00730 1.36e-204 - - - EG - - - EamA-like transporter family
EFBHDGAE_00731 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EFBHDGAE_00732 6.87e-136 - - - K - - - acetyltransferase
EFBHDGAE_00733 8.53e-216 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
EFBHDGAE_00734 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
EFBHDGAE_00735 1.55e-161 arcD - - S - - - C4-dicarboxylate anaerobic carrier
EFBHDGAE_00736 4.48e-279 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
EFBHDGAE_00737 4.06e-107 - - - F - - - Hydrolase, NUDIX family
EFBHDGAE_00738 7.36e-274 - - - S ko:K06915 - ko00000 AAA-like domain
EFBHDGAE_00739 0.0 fusA1 - - J - - - elongation factor G
EFBHDGAE_00740 2.08e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EFBHDGAE_00741 7.6e-145 ypsA - - S - - - Belongs to the UPF0398 family
EFBHDGAE_00742 2.08e-153 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EFBHDGAE_00743 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
EFBHDGAE_00744 6.64e-205 - - - EG - - - EamA-like transporter family
EFBHDGAE_00745 6.71e-243 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
EFBHDGAE_00746 5.43e-190 ypuA - - S - - - Protein of unknown function (DUF1002)
EFBHDGAE_00747 4.14e-173 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
EFBHDGAE_00748 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
EFBHDGAE_00749 6.66e-115 ypmB - - S - - - Protein conserved in bacteria
EFBHDGAE_00750 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
EFBHDGAE_00751 7.57e-215 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
EFBHDGAE_00752 1.56e-232 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
EFBHDGAE_00753 8.24e-271 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
EFBHDGAE_00754 2.15e-262 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EFBHDGAE_00755 1.82e-111 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EFBHDGAE_00758 1.08e-213 - - - L - - - PFAM Integrase catalytic region
EFBHDGAE_00759 1.13e-140 - - - M - - - transferase activity, transferring glycosyl groups
EFBHDGAE_00760 1.49e-105 secY2 - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 SecY translocase
EFBHDGAE_00761 2.8e-123 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
EFBHDGAE_00762 1.34e-159 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
EFBHDGAE_00764 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EFBHDGAE_00766 2.54e-204 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EFBHDGAE_00767 4.88e-156 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EFBHDGAE_00768 3.33e-55 - - - M - - - Glycosyltransferase like family 2
EFBHDGAE_00769 3.83e-144 yckA - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EFBHDGAE_00770 4.86e-199 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
EFBHDGAE_00771 1.36e-139 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
EFBHDGAE_00772 1.54e-92 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
EFBHDGAE_00773 8.6e-93 esbA - - S - - - Family of unknown function (DUF5322)
EFBHDGAE_00774 3e-98 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EFBHDGAE_00775 1.81e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EFBHDGAE_00776 2.95e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
EFBHDGAE_00777 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
EFBHDGAE_00778 3.59e-154 - 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
EFBHDGAE_00779 1.07e-214 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
EFBHDGAE_00780 1.67e-28 - - - S - - - Enoyl-(Acyl carrier protein) reductase
EFBHDGAE_00782 2.47e-275 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
EFBHDGAE_00784 6.53e-123 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
EFBHDGAE_00785 5.05e-128 - - - K - - - Virulence activator alpha C-term
EFBHDGAE_00786 9.67e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
EFBHDGAE_00787 4.81e-08 - - - S - - - SNARE associated Golgi protein
EFBHDGAE_00788 4.53e-303 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
EFBHDGAE_00789 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EFBHDGAE_00791 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
EFBHDGAE_00793 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EFBHDGAE_00794 3.19e-208 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
EFBHDGAE_00795 4.23e-213 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
EFBHDGAE_00796 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EFBHDGAE_00797 5.3e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
EFBHDGAE_00799 1.31e-289 - - - - - - - -
EFBHDGAE_00800 9.18e-246 flp - - V - - - Beta-lactamase
EFBHDGAE_00801 8.23e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
EFBHDGAE_00802 8.47e-159 - - - S ko:K07090 - ko00000 membrane transporter protein
EFBHDGAE_00803 3.14e-237 XK27_12525 - - S - - - AI-2E family transporter
EFBHDGAE_00804 7.67e-273 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EFBHDGAE_00805 8.16e-206 rssA - - S - - - Phospholipase, patatin family
EFBHDGAE_00806 1.35e-214 - - - K - - - LysR substrate binding domain
EFBHDGAE_00807 1.61e-12 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
EFBHDGAE_00808 1.69e-124 - - - V - - - VanZ like family
EFBHDGAE_00809 1.2e-283 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EFBHDGAE_00810 2.74e-81 - - - - - - - -
EFBHDGAE_00811 2.81e-233 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
EFBHDGAE_00812 4.72e-301 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
EFBHDGAE_00813 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
EFBHDGAE_00814 5.8e-220 - - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
EFBHDGAE_00815 2.93e-114 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 ATPase, P-type transporting, HAD superfamily, subfamily IC
EFBHDGAE_00816 2e-109 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
EFBHDGAE_00821 2.83e-115 - - - S ko:K06919 - ko00000 D5 N terminal like
EFBHDGAE_00822 1.15e-195 - - - L - - - DNA replication protein
EFBHDGAE_00824 2.66e-178 int2 - - L - - - Belongs to the 'phage' integrase family
EFBHDGAE_00826 4.19e-106 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
EFBHDGAE_00827 1.6e-54 - - - - - - - -
EFBHDGAE_00828 3.49e-217 - - - GK - - - ROK family
EFBHDGAE_00829 2.9e-164 - - - C - - - Oxidoreductase NAD-binding domain
EFBHDGAE_00830 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
EFBHDGAE_00831 2.68e-134 - - - K - - - Acetyltransferase (GNAT) family
EFBHDGAE_00832 2.51e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFBHDGAE_00833 4.25e-73 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EFBHDGAE_00834 6.33e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EFBHDGAE_00836 5.1e-140 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EFBHDGAE_00837 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EFBHDGAE_00838 1.43e-273 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
EFBHDGAE_00839 2.03e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EFBHDGAE_00840 3.95e-278 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
EFBHDGAE_00841 1.57e-260 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
EFBHDGAE_00842 1.65e-43 - - - M - - - LysM domain
EFBHDGAE_00843 3.94e-53 - - - - - - - -
EFBHDGAE_00844 3.33e-51 - - - S - - - zinc-ribbon domain
EFBHDGAE_00847 3.11e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EFBHDGAE_00848 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EFBHDGAE_00849 9.45e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EFBHDGAE_00850 5.3e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
EFBHDGAE_00851 1.34e-232 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
EFBHDGAE_00852 1.37e-187 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
EFBHDGAE_00853 9.04e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
EFBHDGAE_00854 3.81e-142 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
EFBHDGAE_00855 2.31e-147 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_00856 1.65e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
EFBHDGAE_00857 1.91e-297 ymfF - - S - - - Peptidase M16 inactive domain protein
EFBHDGAE_00858 0.0 ymfH - - S - - - Peptidase M16
EFBHDGAE_00859 1.64e-151 - - - S - - - Helix-turn-helix domain
EFBHDGAE_00860 1.79e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EFBHDGAE_00861 1.62e-293 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
EFBHDGAE_00862 7.88e-245 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EFBHDGAE_00863 2.27e-305 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
EFBHDGAE_00864 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EFBHDGAE_00865 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EFBHDGAE_00866 7.23e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EFBHDGAE_00867 3.61e-243 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EFBHDGAE_00868 1.21e-223 - 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 queuine tRNA-ribosyltransferase activity
EFBHDGAE_00869 7.45e-67 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
EFBHDGAE_00870 3.41e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
EFBHDGAE_00871 1.7e-300 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EFBHDGAE_00872 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EFBHDGAE_00873 1.06e-57 yrzL - - S - - - Belongs to the UPF0297 family
EFBHDGAE_00874 4.97e-97 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EFBHDGAE_00875 7.75e-53 yrzB - - S - - - Belongs to the UPF0473 family
EFBHDGAE_00876 4.55e-211 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EFBHDGAE_00877 2.23e-119 cvpA - - S - - - Colicin V production protein
EFBHDGAE_00878 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EFBHDGAE_00879 1.66e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EFBHDGAE_00880 3.59e-284 - - - P - - - Chloride transporter, ClC family
EFBHDGAE_00881 1.96e-120 yslB - - S - - - Protein of unknown function (DUF2507)
EFBHDGAE_00882 1.06e-188 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EFBHDGAE_00883 1.53e-139 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EFBHDGAE_00884 3.33e-123 - - - S ko:K07095 - ko00000 Phosphoesterase
EFBHDGAE_00885 5.86e-187 - - - S - - - haloacid dehalogenase-like hydrolase
EFBHDGAE_00886 3.7e-201 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
EFBHDGAE_00887 5.14e-68 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EFBHDGAE_00888 4.62e-92 - - - - - - - -
EFBHDGAE_00889 1.54e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
EFBHDGAE_00890 2.94e-238 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
EFBHDGAE_00891 6.95e-182 - - - - - - - -
EFBHDGAE_00892 5.01e-172 yebC - - K - - - Transcriptional regulatory protein
EFBHDGAE_00893 6.81e-123 - - - M - - - PFAM NLP P60 protein
EFBHDGAE_00894 1.05e-183 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
EFBHDGAE_00895 3.88e-64 nlhH_1 - - I ko:K01066 - ko00000,ko01000 acetylesterase activity
EFBHDGAE_00896 4.05e-262 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Domain of unknown function (DUF4982)
EFBHDGAE_00897 4.59e-146 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
EFBHDGAE_00898 2.8e-215 - 3.2.1.37, 3.2.1.55 GH43,GH51 G ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EFBHDGAE_00899 7.92e-170 - - - EGP - - - Major Facilitator Superfamily
EFBHDGAE_00900 4.31e-98 - - - K - - - AraC-like ligand binding domain
EFBHDGAE_00901 0.0 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
EFBHDGAE_00902 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Alpha-L-rhamnosidase N-terminal domain
EFBHDGAE_00903 1.06e-10 - - - I ko:K01066 - ko00000,ko01000 COG0657 Esterase lipase
EFBHDGAE_00904 1.08e-138 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EFBHDGAE_00905 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EFBHDGAE_00906 2.36e-249 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
EFBHDGAE_00907 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
EFBHDGAE_00908 3.02e-126 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
EFBHDGAE_00909 5.55e-182 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
EFBHDGAE_00910 1.71e-211 - - - K - - - LysR substrate binding domain
EFBHDGAE_00911 2.72e-212 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
EFBHDGAE_00912 1.25e-140 - - - - - - - -
EFBHDGAE_00914 9.5e-309 potE - - E - - - Amino Acid
EFBHDGAE_00915 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EFBHDGAE_00916 2.9e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
EFBHDGAE_00917 1.34e-235 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
EFBHDGAE_00918 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
EFBHDGAE_00919 8.66e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
EFBHDGAE_00920 1.47e-127 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
EFBHDGAE_00921 1.38e-252 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
EFBHDGAE_00922 8.39e-114 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EFBHDGAE_00923 1.27e-128 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
EFBHDGAE_00924 4.04e-62 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
EFBHDGAE_00925 9.75e-276 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EFBHDGAE_00926 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
EFBHDGAE_00927 5.4e-175 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
EFBHDGAE_00928 1.55e-65 yktA - - S - - - Belongs to the UPF0223 family
EFBHDGAE_00929 8.59e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EFBHDGAE_00930 6.12e-98 - - - - - - - -
EFBHDGAE_00931 8.83e-43 ykzG - - S - - - Belongs to the UPF0356 family
EFBHDGAE_00932 8.46e-239 - - - I - - - Diacylglycerol kinase catalytic
EFBHDGAE_00933 2.39e-98 - - - P - - - ArsC family
EFBHDGAE_00934 3.81e-228 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EFBHDGAE_00935 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EFBHDGAE_00936 9.37e-159 - - - S - - - repeat protein
EFBHDGAE_00937 4.51e-156 pgm6 - - G - - - phosphoglycerate mutase
EFBHDGAE_00938 1.08e-218 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EFBHDGAE_00939 0.0 - - - S - - - amidohydrolase
EFBHDGAE_00940 1.73e-290 pbuG - - S ko:K06901 - ko00000,ko02000 permease
EFBHDGAE_00941 8.5e-61 - - - - - - - -
EFBHDGAE_00942 1.76e-270 - - - S - - - Putative metallopeptidase domain
EFBHDGAE_00943 9.48e-262 - - - S - - - associated with various cellular activities
EFBHDGAE_00944 2e-150 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
EFBHDGAE_00945 2.45e-86 yeaO - - S - - - Protein of unknown function, DUF488
EFBHDGAE_00947 2.32e-161 yrkL - - S - - - Flavodoxin-like fold
EFBHDGAE_00948 7.49e-74 - - - - - - - -
EFBHDGAE_00949 3.04e-140 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
EFBHDGAE_00950 6.55e-126 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EFBHDGAE_00951 1.68e-138 - - - - - - - -
EFBHDGAE_00952 1.11e-35 - - - - - - - -
EFBHDGAE_00953 6.47e-163 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
EFBHDGAE_00954 7.65e-314 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EFBHDGAE_00955 5.05e-61 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
EFBHDGAE_00956 7.5e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EFBHDGAE_00957 4.81e-157 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_00958 1.02e-33 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
EFBHDGAE_00959 5.95e-100 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
EFBHDGAE_00960 2e-34 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
EFBHDGAE_00961 6.45e-138 - - - K - - - Bacterial regulatory proteins, tetR family
EFBHDGAE_00962 5.52e-241 - - - E - - - Zinc-binding dehydrogenase
EFBHDGAE_00963 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
EFBHDGAE_00964 2.8e-67 - - - - - - - -
EFBHDGAE_00965 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EFBHDGAE_00966 5.56e-110 - - - L - - - nuclease
EFBHDGAE_00967 2.17e-209 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
EFBHDGAE_00968 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EFBHDGAE_00969 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EFBHDGAE_00970 1.24e-258 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EFBHDGAE_00971 1.02e-46 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
EFBHDGAE_00972 3.2e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EFBHDGAE_00973 9.49e-317 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EFBHDGAE_00975 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
EFBHDGAE_00976 2.64e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EFBHDGAE_00977 4.1e-186 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EFBHDGAE_00978 1.06e-197 jag - - S ko:K06346 - ko00000 R3H domain protein
EFBHDGAE_00979 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EFBHDGAE_00980 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EFBHDGAE_00981 1.77e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EFBHDGAE_00982 4.15e-282 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
EFBHDGAE_00983 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EFBHDGAE_00984 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EFBHDGAE_00985 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EFBHDGAE_00986 3.33e-146 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EFBHDGAE_00987 6.02e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
EFBHDGAE_00988 6.56e-165 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EFBHDGAE_00989 1.33e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EFBHDGAE_00990 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
EFBHDGAE_00991 2.63e-99 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
EFBHDGAE_00992 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
EFBHDGAE_00993 6.24e-268 - - - E - - - Major Facilitator Superfamily
EFBHDGAE_00994 2.57e-80 - - - - - - - -
EFBHDGAE_00997 3.03e-167 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
EFBHDGAE_00998 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFBHDGAE_00999 2.98e-305 yycH - - S - - - YycH protein
EFBHDGAE_01000 1.68e-184 yycI - - S - - - YycH protein
EFBHDGAE_01001 5.49e-197 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
EFBHDGAE_01002 2.73e-269 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
EFBHDGAE_01003 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EFBHDGAE_01004 3.03e-94 ywnA - - K - - - Transcriptional regulator
EFBHDGAE_01005 3.97e-226 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
EFBHDGAE_01006 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
EFBHDGAE_01007 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
EFBHDGAE_01008 7.69e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
EFBHDGAE_01009 1.93e-103 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 transmembrane transport
EFBHDGAE_01010 5.38e-158 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
EFBHDGAE_01011 7.41e-61 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EFBHDGAE_01012 9.6e-119 lemA - - S ko:K03744 - ko00000 LemA family
EFBHDGAE_01013 2.22e-201 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
EFBHDGAE_01014 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EFBHDGAE_01015 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EFBHDGAE_01016 1.18e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EFBHDGAE_01017 1.47e-266 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EFBHDGAE_01018 7.09e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
EFBHDGAE_01019 4.51e-148 - - - S - - - (CBS) domain
EFBHDGAE_01020 7.98e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EFBHDGAE_01021 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EFBHDGAE_01022 2.47e-53 yabO - - J - - - S4 domain protein
EFBHDGAE_01023 5.88e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
EFBHDGAE_01024 9.54e-113 yabR - - J ko:K07571 - ko00000 RNA binding
EFBHDGAE_01025 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EFBHDGAE_01026 5.21e-126 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
EFBHDGAE_01027 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EFBHDGAE_01028 1.47e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EFBHDGAE_01029 2.64e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EFBHDGAE_01030 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
EFBHDGAE_01031 1.01e-31 - - - S - - - EpsG family
EFBHDGAE_01032 5.71e-50 murJ - - S ko:K03980 - ko00000,ko01011,ko02000 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EFBHDGAE_01033 2.79e-62 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyltransferase
EFBHDGAE_01034 1.4e-63 - - - M - - - Glycosyltransferase like family 2
EFBHDGAE_01035 1.16e-61 - - - S - - - Polysaccharide pyruvyl transferase
EFBHDGAE_01036 1.65e-110 - - - M - - - Glycosyl transferase family 2
EFBHDGAE_01037 3.11e-123 tuaA - - M - - - Bacterial sugar transferase
EFBHDGAE_01038 8.22e-167 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
EFBHDGAE_01039 1.96e-178 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
EFBHDGAE_01040 1.52e-143 ywqD - - D - - - Capsular exopolysaccharide family
EFBHDGAE_01041 1.52e-166 epsB - - M - - - biosynthesis protein
EFBHDGAE_01042 1.07e-220 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
EFBHDGAE_01043 1.71e-264 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EFBHDGAE_01044 3.37e-175 - - - S - - - Protein of unknown function (DUF1129)
EFBHDGAE_01045 6.1e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EFBHDGAE_01046 1.26e-42 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
EFBHDGAE_01047 1.25e-187 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EFBHDGAE_01048 2.32e-209 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EFBHDGAE_01049 2.04e-170 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
EFBHDGAE_01050 2.31e-185 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
EFBHDGAE_01051 6.02e-270 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
EFBHDGAE_01052 4.35e-108 - - - S - - - Psort location Cytoplasmic, score
EFBHDGAE_01053 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
EFBHDGAE_01054 7.04e-87 - - - K - - - Acetyltransferase (GNAT) family
EFBHDGAE_01055 3.07e-135 - - - NU - - - mannosyl-glycoprotein
EFBHDGAE_01056 7.95e-250 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
EFBHDGAE_01057 7.07e-273 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
EFBHDGAE_01058 1.62e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EFBHDGAE_01059 8.11e-52 - - - S - - - Cytochrome B5
EFBHDGAE_01063 7.81e-201 ycnB - - U - - - Belongs to the major facilitator superfamily
EFBHDGAE_01064 7.34e-93 ycnB - - U - - - Belongs to the major facilitator superfamily
EFBHDGAE_01065 2.79e-125 - - - K - - - transcriptional regulator
EFBHDGAE_01066 1.64e-94 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
EFBHDGAE_01067 0.0 - - - L - - - Helicase C-terminal domain protein
EFBHDGAE_01068 8.93e-71 - - - S - - - MazG-like family
EFBHDGAE_01069 1.53e-138 - - - I - - - PAP2 superfamily
EFBHDGAE_01070 2.48e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
EFBHDGAE_01071 2.56e-123 - - - - - - - -
EFBHDGAE_01072 1.41e-284 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EFBHDGAE_01073 4.59e-218 - - - V - - - Beta-lactamase enzyme family
EFBHDGAE_01074 5.05e-06 potE - - E - - - Amino Acid
EFBHDGAE_01075 2.92e-44 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
EFBHDGAE_01076 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EFBHDGAE_01077 9.45e-208 - - - S - - - Tetratricopeptide repeat
EFBHDGAE_01078 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EFBHDGAE_01079 1.15e-299 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EFBHDGAE_01080 2.06e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EFBHDGAE_01081 4.39e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
EFBHDGAE_01082 5.48e-70 - - - S - - - mazG nucleotide pyrophosphohydrolase
EFBHDGAE_01084 3.97e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_01085 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EFBHDGAE_01086 1.91e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EFBHDGAE_01087 8.64e-225 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EFBHDGAE_01088 1.3e-199 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EFBHDGAE_01089 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
EFBHDGAE_01090 2.41e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EFBHDGAE_01091 1.06e-67 - - - S - - - Domain of unknown function (DUF4440)
EFBHDGAE_01092 1.11e-238 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFBHDGAE_01093 1.06e-193 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
EFBHDGAE_01094 3.67e-72 - - - L ko:K07497 - ko00000 hmm pf00665
EFBHDGAE_01095 8.7e-162 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EFBHDGAE_01096 9.39e-57 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EFBHDGAE_01097 2.65e-54 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
EFBHDGAE_01098 3.19e-244 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
EFBHDGAE_01099 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EFBHDGAE_01100 5.46e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EFBHDGAE_01101 3.97e-174 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
EFBHDGAE_01102 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EFBHDGAE_01103 6.11e-311 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
EFBHDGAE_01104 4.02e-174 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
EFBHDGAE_01106 1.78e-97 uspA3 - - T - - - universal stress protein
EFBHDGAE_01107 6.25e-78 - - - - - - - -
EFBHDGAE_01108 1.25e-09 - - - - - - - -
EFBHDGAE_01109 1.92e-203 - - - - - - - -
EFBHDGAE_01110 2.22e-98 - - - K - - - Transcriptional regulator
EFBHDGAE_01111 6.19e-239 ybcH - - D ko:K06889 - ko00000 Alpha beta
EFBHDGAE_01112 3.85e-95 - - - O - - - OsmC-like protein
EFBHDGAE_01113 5.34e-244 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
EFBHDGAE_01116 8.34e-101 - - - - - - - -
EFBHDGAE_01127 8.21e-07 - - - K - - - Transcriptional regulator
EFBHDGAE_01128 8.27e-184 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EFBHDGAE_01129 5.28e-144 arpJ - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
EFBHDGAE_01130 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
EFBHDGAE_01131 2.99e-144 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EFBHDGAE_01132 1.03e-206 - - - O - - - Uncharacterized protein family (UPF0051)
EFBHDGAE_01133 4.35e-300 - - - F ko:K03458 - ko00000 Permease
EFBHDGAE_01134 2.96e-154 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
EFBHDGAE_01135 1.33e-58 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
EFBHDGAE_01136 8.4e-92 - - - M - - - LysM domain protein
EFBHDGAE_01137 3.6e-112 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
EFBHDGAE_01138 2.79e-102 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EFBHDGAE_01139 3.37e-150 - - - K - - - Transcriptional regulator, TetR family
EFBHDGAE_01142 3.91e-31 - - - - - - - -
EFBHDGAE_01143 1.37e-315 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
EFBHDGAE_01144 3.59e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
EFBHDGAE_01145 0.0 - - - EGP - - - Major Facilitator
EFBHDGAE_01146 1.1e-125 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
EFBHDGAE_01147 3.23e-64 - - - - - - - -
EFBHDGAE_01148 2.19e-270 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EFBHDGAE_01149 1.54e-179 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EFBHDGAE_01150 8.48e-284 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EFBHDGAE_01151 2.93e-163 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
EFBHDGAE_01152 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
EFBHDGAE_01153 9.88e-57 - - - - - - - -
EFBHDGAE_01154 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
EFBHDGAE_01155 1.35e-80 - - - S - - - Domain of unknown function DUF302
EFBHDGAE_01156 5.62e-197 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EFBHDGAE_01157 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
EFBHDGAE_01158 4.06e-113 - - - T - - - Belongs to the universal stress protein A family
EFBHDGAE_01159 0.0 - - - S - - - Putative peptidoglycan binding domain
EFBHDGAE_01160 7.21e-244 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EFBHDGAE_01161 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
EFBHDGAE_01162 9.92e-143 - - - - - - - -
EFBHDGAE_01163 6.39e-235 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
EFBHDGAE_01164 2.89e-152 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
EFBHDGAE_01165 2.44e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EFBHDGAE_01166 7.52e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
EFBHDGAE_01167 3.93e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
EFBHDGAE_01168 4.78e-308 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EFBHDGAE_01169 2.26e-136 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
EFBHDGAE_01170 7.33e-258 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
EFBHDGAE_01172 4.86e-53 - - - - - - - -
EFBHDGAE_01174 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
EFBHDGAE_01175 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EFBHDGAE_01176 3.95e-73 yheA - - S - - - Belongs to the UPF0342 family
EFBHDGAE_01177 5.23e-230 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
EFBHDGAE_01178 6.67e-192 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EFBHDGAE_01180 4.29e-101 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
EFBHDGAE_01181 3.68e-171 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_01182 5.42e-275 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
EFBHDGAE_01183 9.51e-161 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EFBHDGAE_01184 1.68e-76 - - - S - - - Small secreted protein
EFBHDGAE_01185 1.53e-72 ytpP - - CO - - - Thioredoxin
EFBHDGAE_01186 1.11e-152 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EFBHDGAE_01187 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
EFBHDGAE_01188 1.24e-146 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
EFBHDGAE_01189 7.16e-134 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
EFBHDGAE_01190 9.26e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
EFBHDGAE_01191 1.29e-298 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
EFBHDGAE_01192 1.08e-286 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
EFBHDGAE_01194 9.28e-171 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_01195 8.85e-192 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EFBHDGAE_01196 5.66e-231 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
EFBHDGAE_01197 0.0 - - - S - - - ABC transporter, ATP-binding protein
EFBHDGAE_01198 1.35e-261 yngD - - S ko:K07097 - ko00000 DHHA1 domain
EFBHDGAE_01200 8.3e-141 yciB - - M - - - ErfK YbiS YcfS YnhG
EFBHDGAE_01201 1.64e-108 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
EFBHDGAE_01202 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFBHDGAE_01203 1.79e-215 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
EFBHDGAE_01204 8.41e-235 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
EFBHDGAE_01205 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
EFBHDGAE_01206 5.93e-149 - - - S - - - HAD hydrolase, family IA, variant
EFBHDGAE_01207 2.73e-227 - 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
EFBHDGAE_01208 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
EFBHDGAE_01209 4.92e-120 ymdB - - S - - - Macro domain protein
EFBHDGAE_01210 8.79e-188 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
EFBHDGAE_01211 2.57e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EFBHDGAE_01212 4.23e-217 - 1.1.1.399, 1.1.1.95 - CH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFBHDGAE_01213 9.08e-71 - - - - - - - -
EFBHDGAE_01214 1.09e-180 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
EFBHDGAE_01215 1.81e-156 - - - U ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EFBHDGAE_01216 8.36e-174 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_01217 1.21e-48 - - - - - - - -
EFBHDGAE_01218 2.44e-125 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
EFBHDGAE_01219 5.85e-186 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
EFBHDGAE_01220 5.68e-233 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
EFBHDGAE_01221 8.83e-287 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EFBHDGAE_01222 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
EFBHDGAE_01223 3.54e-231 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EFBHDGAE_01224 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
EFBHDGAE_01225 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
EFBHDGAE_01226 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EFBHDGAE_01227 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
EFBHDGAE_01228 6.73e-80 - - - S - - - NADPH-dependent FMN reductase
EFBHDGAE_01229 2.29e-18 - - - S - - - NADPH-dependent FMN reductase
EFBHDGAE_01230 2.16e-201 yneP - - L ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
EFBHDGAE_01231 9.78e-56 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
EFBHDGAE_01232 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
EFBHDGAE_01233 1.18e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
EFBHDGAE_01234 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EFBHDGAE_01235 9.27e-133 - - - K - - - Transcriptional regulator
EFBHDGAE_01236 8.68e-31 XK27_06785 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
EFBHDGAE_01237 1.2e-27 - - - M ko:K02004 - ko00000,ko00002,ko02000 Membrane
EFBHDGAE_01238 3.84e-148 - - - M ko:K02004 - ko00000,ko00002,ko02000 Membrane
EFBHDGAE_01239 5.72e-75 - - - S - - - FMN_bind
EFBHDGAE_01240 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_01241 8.31e-159 - - - K - - - Bacterial regulatory proteins, tetR family
EFBHDGAE_01242 3.08e-259 - 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EFBHDGAE_01244 2.02e-216 - - - H - - - geranyltranstransferase activity
EFBHDGAE_01245 3.43e-235 - - - - - - - -
EFBHDGAE_01246 1.99e-53 - - - - - - - -
EFBHDGAE_01247 6.38e-151 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
EFBHDGAE_01248 9.81e-241 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
EFBHDGAE_01249 1.43e-100 nreA - - T ko:K10851 ko02020,map02020 ko00000,ko00001 GAF domain
EFBHDGAE_01250 6.94e-54 - - - - - - - -
EFBHDGAE_01251 1.01e-127 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EFBHDGAE_01252 6.37e-107 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EFBHDGAE_01253 2.58e-294 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
EFBHDGAE_01254 2.18e-112 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
EFBHDGAE_01255 6.23e-244 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
EFBHDGAE_01256 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EFBHDGAE_01257 0.0 - 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
EFBHDGAE_01258 2.15e-132 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
EFBHDGAE_01259 3.17e-166 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
EFBHDGAE_01260 6.16e-235 - - - - - - - -
EFBHDGAE_01261 1.01e-99 - - - - - - - -
EFBHDGAE_01262 1.86e-82 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
EFBHDGAE_01264 3.94e-314 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
EFBHDGAE_01265 5.19e-207 - - - EG - - - EamA-like transporter family
EFBHDGAE_01266 2.02e-174 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EFBHDGAE_01267 5.49e-181 - - - G - - - MucBP domain
EFBHDGAE_01268 8.07e-126 - - - S - - - Pfam:DUF3816
EFBHDGAE_01269 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EFBHDGAE_01270 8.61e-143 pncA - - Q - - - Isochorismatase family
EFBHDGAE_01271 3.09e-166 - - - F - - - NUDIX domain
EFBHDGAE_01272 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
EFBHDGAE_01273 2.41e-07 - - - - - - - -
EFBHDGAE_01274 2.14e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
EFBHDGAE_01275 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EFBHDGAE_01276 5.62e-294 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
EFBHDGAE_01277 3.81e-255 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
EFBHDGAE_01278 2.79e-231 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EFBHDGAE_01279 2.81e-53 - - - S - - - Protein of unknown function (DUF1797)
EFBHDGAE_01280 4.36e-67 ybjQ - - S - - - Belongs to the UPF0145 family
EFBHDGAE_01281 3.24e-91 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
EFBHDGAE_01282 1.1e-07 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
EFBHDGAE_01283 2.19e-221 - 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
EFBHDGAE_01284 6.7e-72 - - - K - - - Helix-turn-helix domain
EFBHDGAE_01285 2.37e-135 - - - S - - - Domain of unknown function (DUF4767)
EFBHDGAE_01286 3.24e-109 - - - - - - - -
EFBHDGAE_01287 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
EFBHDGAE_01288 3.2e-273 - - - EGP - - - Major Facilitator
EFBHDGAE_01289 9.62e-219 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EFBHDGAE_01290 1.02e-128 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
EFBHDGAE_01291 1.51e-179 - - - K ko:K09705 - ko00000 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EFBHDGAE_01292 2.5e-99 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EFBHDGAE_01293 0.0 - 1.7.2.5 - P ko:K04561 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Cytochrome C and Quinol oxidase polypeptide I
EFBHDGAE_01294 3.39e-193 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
EFBHDGAE_01295 3.31e-162 pgm3 - - G - - - phosphoglycerate mutase family
EFBHDGAE_01296 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EFBHDGAE_01297 9.53e-111 - - - - - - - -
EFBHDGAE_01298 1.69e-145 flp - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
EFBHDGAE_01299 8.02e-130 dpsB - - P - - - Belongs to the Dps family
EFBHDGAE_01300 3.08e-43 copZ - - P - - - Heavy-metal-associated domain
EFBHDGAE_01301 1.1e-143 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
EFBHDGAE_01302 1.62e-121 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
EFBHDGAE_01303 8.65e-97 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
EFBHDGAE_01304 1.51e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
EFBHDGAE_01305 3.41e-231 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
EFBHDGAE_01306 4.09e-131 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
EFBHDGAE_01307 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_01308 1.06e-149 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
EFBHDGAE_01309 1.78e-22 - - - - - - - -
EFBHDGAE_01310 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
EFBHDGAE_01311 1.31e-142 - - - L ko:K07497 - ko00000 hmm pf00665
EFBHDGAE_01315 4.79e-54 - - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
EFBHDGAE_01316 6.05e-22 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EFBHDGAE_01317 1.51e-131 - - - K - - - DNA-templated transcription, initiation
EFBHDGAE_01319 0.0 - - - L - - - Type III restriction enzyme, res subunit
EFBHDGAE_01320 6.4e-71 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
EFBHDGAE_01322 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
EFBHDGAE_01323 6.4e-149 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_01324 3.1e-170 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
EFBHDGAE_01325 4.21e-116 rmeB - - K - - - transcriptional regulator, MerR family
EFBHDGAE_01326 9.98e-40 yrfB - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
EFBHDGAE_01327 9.46e-199 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EFBHDGAE_01328 7.42e-258 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EFBHDGAE_01329 0.0 - - - L - - - DNA helicase
EFBHDGAE_01330 7.95e-222 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
EFBHDGAE_01331 2.75e-286 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
EFBHDGAE_01332 9.16e-240 - - - - - - - -
EFBHDGAE_01333 9.4e-165 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
EFBHDGAE_01334 1.37e-271 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
EFBHDGAE_01335 4.06e-208 yunF - - F - - - Protein of unknown function DUF72
EFBHDGAE_01336 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EFBHDGAE_01337 1.1e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
EFBHDGAE_01338 2.18e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EFBHDGAE_01339 5.08e-205 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EFBHDGAE_01340 4.04e-205 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EFBHDGAE_01341 1.36e-97 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
EFBHDGAE_01342 5.1e-64 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
EFBHDGAE_01343 3.85e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
EFBHDGAE_01344 4.36e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EFBHDGAE_01345 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EFBHDGAE_01346 2.16e-97 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EFBHDGAE_01347 5.23e-97 ywiB - - S - - - Domain of unknown function (DUF1934)
EFBHDGAE_01348 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
EFBHDGAE_01349 1.01e-184 yidA - - S - - - hydrolase
EFBHDGAE_01350 2.68e-78 - - - - - - - -
EFBHDGAE_01351 7.69e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EFBHDGAE_01352 9.91e-302 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EFBHDGAE_01353 2.13e-193 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
EFBHDGAE_01354 2.81e-166 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
EFBHDGAE_01355 1.98e-123 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EFBHDGAE_01356 4.04e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EFBHDGAE_01357 6.15e-93 - - - L ko:K07491 - ko00000 Transposase IS200 like
EFBHDGAE_01358 2.4e-176 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
EFBHDGAE_01359 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EFBHDGAE_01360 7.57e-208 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EFBHDGAE_01361 4.15e-137 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EFBHDGAE_01362 3.44e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EFBHDGAE_01363 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
EFBHDGAE_01364 7.63e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
EFBHDGAE_01365 6.95e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EFBHDGAE_01366 5.22e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
EFBHDGAE_01367 4.67e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EFBHDGAE_01368 2.58e-24 - - - S - - - Protein of unknown function (DUF1275)
EFBHDGAE_01369 7.57e-33 - - - S - - - Protein of unknown function (DUF1275)
EFBHDGAE_01370 6.88e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
EFBHDGAE_01371 2.29e-275 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
EFBHDGAE_01372 1.38e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
EFBHDGAE_01373 9.34e-120 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EFBHDGAE_01374 5.53e-145 yqeK - - H - - - Hydrolase, HD family
EFBHDGAE_01375 4.82e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EFBHDGAE_01376 1.83e-180 yqeM - - Q - - - Methyltransferase
EFBHDGAE_01377 8.29e-274 ylbM - - S - - - Belongs to the UPF0348 family
EFBHDGAE_01378 2.79e-126 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
EFBHDGAE_01379 7.89e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
EFBHDGAE_01380 1.38e-155 csrR - - K - - - response regulator
EFBHDGAE_01381 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFBHDGAE_01382 1.88e-298 - - - V - - - MatE
EFBHDGAE_01383 4.54e-91 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
EFBHDGAE_01384 1.43e-199 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EFBHDGAE_01385 6.69e-61 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
EFBHDGAE_01386 1.84e-180 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EFBHDGAE_01387 4.08e-117 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
EFBHDGAE_01388 1.44e-78 yodB - - K - - - Transcriptional regulator, HxlR family
EFBHDGAE_01389 4.45e-253 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EFBHDGAE_01390 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EFBHDGAE_01391 2.93e-151 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
EFBHDGAE_01392 1.81e-103 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EFBHDGAE_01393 0.0 - - - S - - - membrane
EFBHDGAE_01394 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EFBHDGAE_01395 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EFBHDGAE_01396 1.22e-125 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EFBHDGAE_01397 9.2e-134 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
EFBHDGAE_01398 1.14e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
EFBHDGAE_01399 5.87e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
EFBHDGAE_01400 5.91e-93 yqhL - - P - - - Rhodanese-like protein
EFBHDGAE_01401 3.51e-33 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
EFBHDGAE_01402 6.29e-221 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EFBHDGAE_01403 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
EFBHDGAE_01404 4.76e-19 - - - - - - - -
EFBHDGAE_01405 8.07e-203 - - - - - - - -
EFBHDGAE_01406 5.32e-229 - - - - - - - -
EFBHDGAE_01407 1.1e-120 - - - S - - - Protein conserved in bacteria
EFBHDGAE_01409 3.17e-149 - - - K - - - Transcriptional regulator
EFBHDGAE_01410 1.89e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
EFBHDGAE_01411 1.2e-70 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
EFBHDGAE_01412 8.74e-62 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
EFBHDGAE_01413 5.7e-261 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
EFBHDGAE_01414 2.1e-94 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
EFBHDGAE_01415 4.67e-90 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EFBHDGAE_01416 2e-206 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EFBHDGAE_01417 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EFBHDGAE_01418 1.64e-25 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EFBHDGAE_01419 8.41e-202 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EFBHDGAE_01420 1.14e-189 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
EFBHDGAE_01421 4.92e-99 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EFBHDGAE_01422 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
EFBHDGAE_01423 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EFBHDGAE_01424 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EFBHDGAE_01425 1.75e-180 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EFBHDGAE_01426 9e-184 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EFBHDGAE_01427 2.84e-134 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EFBHDGAE_01428 6.81e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EFBHDGAE_01429 1.4e-87 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
EFBHDGAE_01430 1.17e-51 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
EFBHDGAE_01431 1.73e-38 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EFBHDGAE_01432 1.93e-52 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EFBHDGAE_01433 2.52e-203 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EFBHDGAE_01434 4.16e-135 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EFBHDGAE_01435 3.64e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
EFBHDGAE_01436 3.14e-132 cadD - - P - - - Cadmium resistance transporter
EFBHDGAE_01437 1.02e-256 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
EFBHDGAE_01438 1.48e-46 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EFBHDGAE_01440 9.46e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_01441 2.08e-84 - - - K - - - Transcriptional regulator, GntR family
EFBHDGAE_01442 2.63e-214 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EFBHDGAE_01443 6.16e-100 - - - S - - - Bacterial membrane protein, YfhO
EFBHDGAE_01444 2.11e-126 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
EFBHDGAE_01445 2.62e-119 - - - M - - - transferase activity, transferring glycosyl groups
EFBHDGAE_01446 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EFBHDGAE_01447 1.74e-209 ykoT - - M - - - Glycosyl transferase family 2
EFBHDGAE_01448 1.45e-216 yueF - - S - - - AI-2E family transporter
EFBHDGAE_01449 3.27e-204 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
EFBHDGAE_01450 8.03e-10 - - - - - - - -
EFBHDGAE_01451 1.51e-78 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
EFBHDGAE_01452 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EFBHDGAE_01453 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
EFBHDGAE_01454 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EFBHDGAE_01455 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
EFBHDGAE_01456 4.17e-237 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
EFBHDGAE_01457 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
EFBHDGAE_01458 8.24e-71 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EFBHDGAE_01459 3.88e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EFBHDGAE_01460 4.47e-312 steT - - E ko:K03294 - ko00000 amino acid
EFBHDGAE_01461 2.02e-116 - - - P - - - Cadmium resistance transporter
EFBHDGAE_01462 1.05e-44 ydzE - - EG - - - spore germination
EFBHDGAE_01463 4.25e-71 - 4.1.1.44 - O ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EFBHDGAE_01464 3.94e-101 - - - - - - - -
EFBHDGAE_01465 0.0 - - - M - - - Iron Transport-associated domain
EFBHDGAE_01466 5.34e-129 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
EFBHDGAE_01467 1.55e-193 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EFBHDGAE_01468 3.64e-200 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFBHDGAE_01469 8.62e-179 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_01470 3.2e-301 proP - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
EFBHDGAE_01471 4.37e-10 - - - S - - - YSIRK type signal peptide
EFBHDGAE_01472 2e-203 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
EFBHDGAE_01473 9.56e-38 - - - S - - - Putative threonine/serine exporter
EFBHDGAE_01474 8.17e-107 - - - S - - - Threonine/Serine exporter, ThrE
EFBHDGAE_01475 2.57e-148 - - - I - - - phosphatase
EFBHDGAE_01476 7.25e-201 - - - I - - - alpha/beta hydrolase fold
EFBHDGAE_01478 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
EFBHDGAE_01479 4.69e-151 dgk2 - - F - - - deoxynucleoside kinase
EFBHDGAE_01485 5.16e-15 fabG1 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFBHDGAE_01486 1.77e-58 - - - IQ - - - reductase
EFBHDGAE_01487 7.14e-191 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EFBHDGAE_01488 1.3e-23 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
EFBHDGAE_01490 6.8e-52 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
EFBHDGAE_01491 2.75e-42 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Hexapeptide repeat of succinyl-transferase
EFBHDGAE_01492 1.49e-154 - - - J - - - 2'-5' RNA ligase superfamily
EFBHDGAE_01493 1.97e-169 XK27_07210 - - S - - - B3 4 domain
EFBHDGAE_01494 1.37e-247 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
EFBHDGAE_01495 3.66e-315 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EFBHDGAE_01496 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
EFBHDGAE_01497 3.68e-278 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EFBHDGAE_01498 9.8e-09 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
EFBHDGAE_01499 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFBHDGAE_01500 1.58e-306 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
EFBHDGAE_01501 3.78e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFBHDGAE_01502 2.9e-311 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EFBHDGAE_01503 3.78e-155 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
EFBHDGAE_01504 2e-24 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EFBHDGAE_01505 1.74e-107 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EFBHDGAE_01506 7.99e-312 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EFBHDGAE_01507 6.9e-279 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
EFBHDGAE_01508 3.68e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EFBHDGAE_01509 4.22e-245 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EFBHDGAE_01510 7.77e-197 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EFBHDGAE_01511 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
EFBHDGAE_01512 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
EFBHDGAE_01513 1.97e-62 - - - - - - - -
EFBHDGAE_01514 8.33e-34 gntT - - EG - - - gluconate transmembrane transporter activity
EFBHDGAE_01515 1.63e-174 - - - L - - - Transposase DDE domain group 1
EFBHDGAE_01517 1.17e-82 lemA - - S ko:K03744 - ko00000 LemA family
EFBHDGAE_01518 3.12e-68 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
EFBHDGAE_01519 6.5e-81 - - - - - - - -
EFBHDGAE_01522 5.5e-244 - - - EGP - - - Major Facilitator
EFBHDGAE_01524 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Aluminium induced protein
EFBHDGAE_01526 3.89e-195 - - - S ko:K07088 - ko00000 Membrane transport protein
EFBHDGAE_01527 5.57e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EFBHDGAE_01528 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
EFBHDGAE_01529 7.27e-266 - - - EGP - - - Major Facilitator
EFBHDGAE_01530 2.07e-258 ycsG - - P - - - Natural resistance-associated macrophage protein
EFBHDGAE_01531 2.12e-174 - - - S ko:K07160 - ko00000 LamB/YcsF family
EFBHDGAE_01532 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
EFBHDGAE_01533 1.12e-86 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EFBHDGAE_01534 1.42e-244 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
EFBHDGAE_01535 4.42e-172 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
EFBHDGAE_01536 9.42e-95 - - - K - - - helix_turn_helix, mercury resistance
EFBHDGAE_01537 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
EFBHDGAE_01538 1.07e-197 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
EFBHDGAE_01539 1.12e-213 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EFBHDGAE_01540 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
EFBHDGAE_01541 7.26e-192 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EFBHDGAE_01542 8.25e-57 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EFBHDGAE_01543 6.31e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EFBHDGAE_01544 3.99e-231 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
EFBHDGAE_01545 1.43e-18 ycsI - - S - - - Protein of unknown function (DUF1445)
EFBHDGAE_01546 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EFBHDGAE_01547 1.25e-237 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
EFBHDGAE_01548 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EFBHDGAE_01549 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EFBHDGAE_01550 1.71e-65 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EFBHDGAE_01551 7.07e-236 camS - - S - - - sex pheromone
EFBHDGAE_01552 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EFBHDGAE_01553 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
EFBHDGAE_01554 1.76e-278 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EFBHDGAE_01555 2.25e-131 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EFBHDGAE_01556 9.5e-142 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
EFBHDGAE_01557 4.28e-178 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
EFBHDGAE_01558 3.59e-264 - - - S - - - interspecies interaction between organisms
EFBHDGAE_01559 2.78e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
EFBHDGAE_01560 5.57e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EFBHDGAE_01561 8.08e-188 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EFBHDGAE_01562 1.6e-178 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFBHDGAE_01563 8.38e-201 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFBHDGAE_01564 4.31e-193 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFBHDGAE_01565 1.02e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
EFBHDGAE_01566 1.41e-216 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFBHDGAE_01567 8.02e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EFBHDGAE_01568 1.32e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EFBHDGAE_01569 6.38e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
EFBHDGAE_01570 1.69e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EFBHDGAE_01571 2.16e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EFBHDGAE_01572 1.36e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EFBHDGAE_01573 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
EFBHDGAE_01574 1.2e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
EFBHDGAE_01575 3.59e-113 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EFBHDGAE_01576 5.55e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EFBHDGAE_01577 1.02e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EFBHDGAE_01578 2.19e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EFBHDGAE_01579 2.46e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EFBHDGAE_01580 1.75e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EFBHDGAE_01581 1.28e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EFBHDGAE_01582 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EFBHDGAE_01583 4.48e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EFBHDGAE_01584 1.35e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
EFBHDGAE_01585 2.78e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EFBHDGAE_01586 3.43e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EFBHDGAE_01587 2.63e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EFBHDGAE_01588 6.15e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EFBHDGAE_01589 3.32e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EFBHDGAE_01590 2.76e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EFBHDGAE_01591 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
EFBHDGAE_01592 5.89e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EFBHDGAE_01593 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
EFBHDGAE_01594 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EFBHDGAE_01595 4.15e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EFBHDGAE_01596 3.58e-93 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EFBHDGAE_01597 1.77e-40 pilD 3.4.23.43 - NOU ko:K02236,ko:K02506,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 aspartic-type endopeptidase activity
EFBHDGAE_01598 3.02e-275 - - - - - - - -
EFBHDGAE_01599 2.92e-173 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
EFBHDGAE_01600 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFBHDGAE_01601 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFBHDGAE_01602 8.51e-137 - - - K - - - Bacterial regulatory proteins, tetR family
EFBHDGAE_01603 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EFBHDGAE_01604 6.36e-103 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
EFBHDGAE_01605 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EFBHDGAE_01606 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
EFBHDGAE_01607 8.61e-89 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EFBHDGAE_01608 6.47e-213 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EFBHDGAE_01609 4.96e-219 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
EFBHDGAE_01610 2.05e-147 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EFBHDGAE_01611 7.11e-254 - - - S - - - Domain of unknown function (DUF4432)
EFBHDGAE_01612 1.49e-223 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EFBHDGAE_01613 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
EFBHDGAE_01614 8.93e-185 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EFBHDGAE_01615 4.46e-196 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
EFBHDGAE_01616 1.41e-286 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
EFBHDGAE_01620 2.42e-43 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
EFBHDGAE_01621 5.61e-41 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
EFBHDGAE_01622 7.23e-46 - - - E - - - Zinc-binding dehydrogenase
EFBHDGAE_01623 1.51e-28 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
EFBHDGAE_01624 1.04e-47 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
EFBHDGAE_01625 0.0 guaD 3.5.4.3 - F ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
EFBHDGAE_01626 1.97e-276 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
EFBHDGAE_01627 3.42e-194 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
EFBHDGAE_01628 1.33e-228 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
EFBHDGAE_01629 8.31e-210 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
EFBHDGAE_01630 8.88e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
EFBHDGAE_01635 7.51e-204 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
EFBHDGAE_01636 9.57e-287 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EFBHDGAE_01637 2.73e-147 - - - S - - - Calcineurin-like phosphoesterase
EFBHDGAE_01638 2.7e-126 yutD - - S - - - Protein of unknown function (DUF1027)
EFBHDGAE_01639 1.01e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EFBHDGAE_01640 2.65e-21 - - - S - - - Protein of unknown function (DUF1461)
EFBHDGAE_01641 8.3e-142 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
EFBHDGAE_01642 4.86e-57 - - - L ko:K07491 - ko00000 Transposase IS200 like
EFBHDGAE_01644 1.2e-240 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EFBHDGAE_01646 1.39e-288 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EFBHDGAE_01647 4.47e-175 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_01648 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
EFBHDGAE_01649 6.32e-118 - - - L - - - Transposase and inactivated derivatives, IS30 family
EFBHDGAE_01650 4.6e-271 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
EFBHDGAE_01651 8.42e-281 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EFBHDGAE_01652 9.72e-107 - - - K - - - Transcriptional regulator
EFBHDGAE_01653 1.06e-96 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EFBHDGAE_01654 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EFBHDGAE_01655 4.23e-76 - - - - - - - -
EFBHDGAE_01656 2.59e-175 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EFBHDGAE_01657 6.27e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
EFBHDGAE_01658 4.82e-72 - - - - - - - -
EFBHDGAE_01659 2.37e-65 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EFBHDGAE_01660 1.37e-249 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EFBHDGAE_01661 8.11e-159 cas4 3.1.12.1 - L ko:K07464 - ko00000,ko01000,ko02048 Domain of unknown function DUF83
EFBHDGAE_01662 2.95e-207 csd2 - - L ko:K19115,ko:K19118 - ko00000,ko02048 CRISPR-associated protein Cas7
EFBHDGAE_01663 0.0 csd1 - - M ko:K19117 - ko00000,ko02048 CRISPR-associated protein (Cas_Csd1)
EFBHDGAE_01664 1.2e-183 cas5 - - S ko:K19119 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
EFBHDGAE_01665 0.0 - - - L ko:K07012 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
EFBHDGAE_01666 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
EFBHDGAE_01667 7.54e-59 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EFBHDGAE_01669 2.48e-78 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EFBHDGAE_01670 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EFBHDGAE_01671 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EFBHDGAE_01672 6.31e-204 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EFBHDGAE_01673 6.87e-117 yejD 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 nucleoside 2-deoxyribosyltransferase
EFBHDGAE_01674 4.65e-34 - - - EGP - - - Major Facilitator
EFBHDGAE_01675 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
EFBHDGAE_01676 2.29e-68 - - - S - - - Cupredoxin-like domain
EFBHDGAE_01677 4.36e-67 - - - S - - - Cupredoxin-like domain
EFBHDGAE_01678 2.76e-224 - - - - - - - -
EFBHDGAE_01679 6.98e-286 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EFBHDGAE_01680 4.68e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EFBHDGAE_01681 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
EFBHDGAE_01682 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
EFBHDGAE_01683 2.2e-227 - - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
EFBHDGAE_01684 1.37e-196 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
EFBHDGAE_01686 2.17e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
EFBHDGAE_01687 9.4e-231 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFBHDGAE_01688 7.47e-174 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
EFBHDGAE_01689 6e-53 - - - C - - - Protein of unknown function (DUF1116)
EFBHDGAE_01691 0.000699 - - - S - - - Protein of unknown function (DUF2877)
EFBHDGAE_01692 1.37e-153 cpkA 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Amino acid kinase family
EFBHDGAE_01693 1.23e-225 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
EFBHDGAE_01694 3.88e-160 - - - C - - - nitroreductase
EFBHDGAE_01695 1.98e-176 - - - E - - - GDSL-like Lipase/Acylhydrolase family
EFBHDGAE_01696 3.25e-38 - - - L - - - Helix-turn-helix domain
EFBHDGAE_01697 6.37e-95 crtM 2.5.1.32, 2.5.1.96, 2.5.1.99 - I ko:K02291,ko:K10208 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
EFBHDGAE_01698 1.1e-313 - - - U - - - Belongs to the major facilitator superfamily
EFBHDGAE_01699 7.19e-234 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
EFBHDGAE_01700 3.22e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EFBHDGAE_01701 1.49e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EFBHDGAE_01702 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EFBHDGAE_01703 5.5e-67 ylxQ - - J - - - ribosomal protein
EFBHDGAE_01704 3.71e-64 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
EFBHDGAE_01705 1.92e-282 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
EFBHDGAE_01706 8.99e-109 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
EFBHDGAE_01707 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
EFBHDGAE_01708 6.19e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EFBHDGAE_01709 8.62e-252 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EFBHDGAE_01710 1.49e-265 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EFBHDGAE_01711 5.88e-176 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
EFBHDGAE_01712 1.33e-274 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
EFBHDGAE_01713 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EFBHDGAE_01714 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EFBHDGAE_01715 7.18e-297 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
EFBHDGAE_01716 8.21e-174 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
EFBHDGAE_01717 2.7e-185 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EFBHDGAE_01718 6.51e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EFBHDGAE_01719 6.84e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
EFBHDGAE_01720 3.4e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EFBHDGAE_01721 3.14e-181 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
EFBHDGAE_01722 2.67e-62 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
EFBHDGAE_01723 6.86e-176 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
EFBHDGAE_01724 3.06e-150 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
EFBHDGAE_01725 1.05e-36 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
EFBHDGAE_01726 1.97e-49 ynzC - - S - - - UPF0291 protein
EFBHDGAE_01727 4.36e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EFBHDGAE_01728 9.01e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
EFBHDGAE_01729 2.76e-155 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
EFBHDGAE_01730 1.07e-307 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
EFBHDGAE_01731 3.38e-111 lutC - - S ko:K00782 - ko00000 LUD domain
EFBHDGAE_01732 1.45e-34 - - - M - - - LPXTG-motif cell wall anchor domain protein
EFBHDGAE_01733 1.2e-61 - - - M - - - LPXTG-motif cell wall anchor domain protein
EFBHDGAE_01734 1.97e-48 - - - M - - - domain protein
EFBHDGAE_01735 2.72e-11 - - - Q - - - Signal peptide protein, YSIRK family
EFBHDGAE_01736 3.02e-35 yitW - - S - - - DNA methyltransferase
EFBHDGAE_01737 2.53e-140 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
EFBHDGAE_01738 1.41e-83 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
EFBHDGAE_01741 1.78e-105 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
EFBHDGAE_01742 1.76e-144 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
EFBHDGAE_01743 2.51e-151 - - - L - - - Transposase DDE domain
EFBHDGAE_01745 2.79e-91 - - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
EFBHDGAE_01746 4.23e-90 - - - U - - - type IV secretory pathway VirB4
EFBHDGAE_01747 6.91e-12 traE - - U - - - Psort location Cytoplasmic, score
EFBHDGAE_01748 5.97e-38 - - - - - - - -
EFBHDGAE_01749 9.98e-33 - - - - - - - -
EFBHDGAE_01750 1.48e-68 - - - - - - - -
EFBHDGAE_01751 2.58e-65 - - - S - - - Cag pathogenicity island, type IV secretory system
EFBHDGAE_01752 2.06e-104 - - - - - - - -
EFBHDGAE_01755 2.04e-134 - - - S - - - Bacterial transferase hexapeptide (six repeats)
EFBHDGAE_01756 9.06e-37 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EFBHDGAE_01757 1.53e-58 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EFBHDGAE_01758 6.09e-254 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
EFBHDGAE_01759 3.49e-13 - - - K - - - transcriptional
EFBHDGAE_01760 1.56e-67 - - - S - - - Sugar efflux transporter for intercellular exchange
EFBHDGAE_01761 1.75e-73 - - - S - - - Antibiotic biosynthesis monooxygenase
EFBHDGAE_01762 3.41e-58 - - - S - - - Protein conserved in bacteria
EFBHDGAE_01763 1.34e-126 ydeQ - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
EFBHDGAE_01764 1.17e-74 manO - - S - - - Domain of unknown function (DUF956)
EFBHDGAE_01765 1.37e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
EFBHDGAE_01766 2.38e-164 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
EFBHDGAE_01767 2.22e-231 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
EFBHDGAE_01768 1.5e-231 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
EFBHDGAE_01769 2.52e-116 - - - K - - - Domain of unknown function (DUF1836)
EFBHDGAE_01770 1.33e-192 yitS - - S - - - EDD domain protein, DegV family
EFBHDGAE_01771 4.7e-165 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EFBHDGAE_01772 3.1e-16 - - - S - - - YjcQ protein
EFBHDGAE_01773 2.47e-189 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EFBHDGAE_01774 2.3e-173 - - - S - - - Membrane
EFBHDGAE_01775 1.52e-98 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
EFBHDGAE_01776 4.66e-110 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
EFBHDGAE_01777 1.3e-300 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
EFBHDGAE_01779 5e-106 uspA - - T - - - universal stress protein
EFBHDGAE_01780 1.63e-193 - - - K - - - Helix-turn-helix XRE-family like proteins
EFBHDGAE_01781 1.43e-114 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EFBHDGAE_01782 2.93e-47 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EFBHDGAE_01783 1.34e-42 - - - S - - - CRISPR-associated protein (Cas_Csn2)
EFBHDGAE_01785 5.27e-41 - - - I - - - Hydrolase, alpha beta domain protein
EFBHDGAE_01786 3.26e-42 - - - I ko:K01066 - ko00000,ko01000 Esterase lipase
EFBHDGAE_01788 2.56e-126 - - - S - - - integral membrane protein
EFBHDGAE_01789 4.78e-221 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
EFBHDGAE_01791 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
EFBHDGAE_01792 1.88e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
EFBHDGAE_01793 1.24e-196 - - - U ko:K05340 - ko00000,ko02000 sugar transport
EFBHDGAE_01794 0.0 yclK - - T - - - Histidine kinase
EFBHDGAE_01795 2.8e-170 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
EFBHDGAE_01797 1e-20 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EFBHDGAE_01799 2.49e-180 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
EFBHDGAE_01801 1.24e-66 - - - K - - - Transcriptional regulator
EFBHDGAE_01802 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
EFBHDGAE_01803 1.81e-251 adh1 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
EFBHDGAE_01804 1.53e-63 - - - S - - - Mazg nucleotide pyrophosphohydrolase
EFBHDGAE_01805 1.16e-06 - - - L - - - MULE transposase domain
EFBHDGAE_01808 7.16e-189 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EFBHDGAE_01809 0.0 - - - L - - - Type III restriction enzyme, res subunit
EFBHDGAE_01810 3.87e-77 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
EFBHDGAE_01812 3.39e-147 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
EFBHDGAE_01813 3.24e-147 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
EFBHDGAE_01814 1.19e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EFBHDGAE_01815 8.7e-196 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
EFBHDGAE_01816 1.6e-38 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
EFBHDGAE_01818 3.97e-83 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
EFBHDGAE_01819 2.17e-86 - - - S - - - enterobacterial common antigen metabolic process
EFBHDGAE_01820 1.24e-256 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
EFBHDGAE_01821 4.65e-279 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
EFBHDGAE_01822 1.34e-39 - - - M - - - biosynthesis protein
EFBHDGAE_01823 4.76e-117 cps3F - - - - - - -
EFBHDGAE_01824 1.71e-191 cps1D - - M - - - Domain of unknown function (DUF4422)
EFBHDGAE_01825 1.73e-152 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
EFBHDGAE_01826 2.39e-187 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
EFBHDGAE_01828 4.37e-43 - - - S - - - Protein of unknown function (DUF2922)
EFBHDGAE_01829 1.01e-192 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
EFBHDGAE_01830 0.0 XK27_08315 - - M - - - Sulfatase
EFBHDGAE_01831 4.08e-215 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
EFBHDGAE_01832 1.66e-101 ykuP - - C ko:K03839 - ko00000 Flavodoxin
EFBHDGAE_01833 1.38e-98 gtcA - - S - - - Teichoic acid glycosylation protein
EFBHDGAE_01835 1.42e-305 yfmL - - L - - - DEAD DEAH box helicase
EFBHDGAE_01836 4.94e-244 mocA - - S - - - Oxidoreductase
EFBHDGAE_01837 2.11e-82 - - - S - - - Domain of unknown function (DUF4828)
EFBHDGAE_01838 1.73e-132 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
EFBHDGAE_01839 1.92e-207 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EFBHDGAE_01840 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
EFBHDGAE_01841 2.03e-177 - - - S - - - NADPH-dependent FMN reductase
EFBHDGAE_01842 2.89e-44 yneR - - S - - - Belongs to the HesB IscA family
EFBHDGAE_01843 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
EFBHDGAE_01844 1.76e-113 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
EFBHDGAE_01845 1.27e-135 - - - - - - - -
EFBHDGAE_01846 6.55e-275 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
EFBHDGAE_01847 2.39e-131 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EFBHDGAE_01848 1.3e-79 - - - EGP - - - Major Facilitator Superfamily
EFBHDGAE_01849 1.71e-59 - - - EGP - - - Major Facilitator Superfamily
EFBHDGAE_01850 6.2e-129 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EFBHDGAE_01851 1.35e-133 - - - S - - - CAAX protease self-immunity
EFBHDGAE_01853 1.17e-152 - - - Q - - - Methyltransferase domain
EFBHDGAE_01854 1.03e-120 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
EFBHDGAE_01855 1.28e-67 - - - K - - - 2 iron, 2 sulfur cluster binding
EFBHDGAE_01856 0.0 sufI - - Q - - - Multicopper oxidase
EFBHDGAE_01857 4.53e-115 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
EFBHDGAE_01858 1.32e-95 - 3.5.3.18 - E ko:K01482 - ko00000,ko01000,ko04147 Amidinotransferase
EFBHDGAE_01860 1.86e-248 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
EFBHDGAE_01861 3.02e-234 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
EFBHDGAE_01862 1.25e-135 - - - L - - - MULE transposase domain
EFBHDGAE_01863 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
EFBHDGAE_01864 2.74e-145 - - - T - - - Region found in RelA / SpoT proteins
EFBHDGAE_01865 3.32e-101 dltr - - K - - - response regulator
EFBHDGAE_01866 5.92e-164 sptS - - T - - - Histidine kinase
EFBHDGAE_01867 8.45e-75 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EFBHDGAE_01868 3.51e-183 yceF - - P ko:K05794 - ko00000 membrane
EFBHDGAE_01869 1.42e-215 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EFBHDGAE_01870 6.8e-220 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
EFBHDGAE_01871 2.74e-302 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
EFBHDGAE_01872 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
EFBHDGAE_01873 7.2e-49 B4168_4126 - - L ko:K07493 - ko00000 Transposase
EFBHDGAE_01874 2.11e-95 B4168_4126 - - L ko:K07493 - ko00000 Transposase
EFBHDGAE_01876 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
EFBHDGAE_01877 5.51e-46 - - - C - - - Heavy-metal-associated domain
EFBHDGAE_01878 4.3e-122 dpsB - - P - - - Belongs to the Dps family
EFBHDGAE_01879 4.13e-147 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
EFBHDGAE_01880 9.4e-46 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
EFBHDGAE_01881 4.17e-236 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
EFBHDGAE_01882 3.45e-207 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
EFBHDGAE_01883 1.72e-213 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EFBHDGAE_01884 7.61e-68 bamA - - GM ko:K07277,ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko02000,ko03016,ko03019,ko03029 domain, Protein
EFBHDGAE_01888 2.96e-132 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EFBHDGAE_01889 3.89e-75 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
EFBHDGAE_01890 6.17e-238 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
EFBHDGAE_01891 8.43e-97 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EFBHDGAE_01892 5.52e-240 - - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
EFBHDGAE_01893 0.0 potE - - E - - - Amino Acid
EFBHDGAE_01894 3.86e-282 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
EFBHDGAE_01896 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
EFBHDGAE_01897 2.11e-56 - - - - - - - -
EFBHDGAE_01898 9.13e-17 - - - - - - - -
EFBHDGAE_01899 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
EFBHDGAE_01901 5.61e-301 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
EFBHDGAE_01902 1.29e-109 - - - S - - - Alpha beta hydrolase
EFBHDGAE_01903 9.03e-55 - - - S - - - Alpha beta hydrolase
EFBHDGAE_01904 6.38e-118 - - - GM - - - NAD(P)H-binding
EFBHDGAE_01905 7.06e-58 - - - GM - - - NAD(P)H-binding
EFBHDGAE_01906 2.15e-194 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
EFBHDGAE_01909 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
EFBHDGAE_01911 3.92e-100 - - - G - - - Major Facilitator Superfamily
EFBHDGAE_01912 8.63e-145 - - - G - - - Major Facilitator Superfamily
EFBHDGAE_01913 7.56e-15 aroH 5.4.99.5 - E ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
EFBHDGAE_01914 4.62e-273 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EFBHDGAE_01915 1.9e-132 - - - - - - - -
EFBHDGAE_01916 1.58e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EFBHDGAE_01917 1.95e-249 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
EFBHDGAE_01918 8.74e-116 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EFBHDGAE_01919 5.24e-278 aspB3 - - E - - - DegT/DnrJ/EryC1/StrS aminotransferase family
EFBHDGAE_01920 6.92e-235 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFBHDGAE_01921 3.65e-226 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EFBHDGAE_01922 9.02e-201 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
EFBHDGAE_01923 1.25e-31 - - - S - - - Virus attachment protein p12 family
EFBHDGAE_01924 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
EFBHDGAE_01925 2e-45 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
EFBHDGAE_01926 2.69e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
EFBHDGAE_01927 7.7e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
EFBHDGAE_01928 1.06e-297 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EFBHDGAE_01929 2.14e-110 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
EFBHDGAE_01930 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
EFBHDGAE_01931 1.72e-244 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EFBHDGAE_01932 1.12e-181 - - - EG - - - EamA-like transporter family
EFBHDGAE_01933 0.0 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
EFBHDGAE_01934 4.24e-26 - - - S - - - Domain of unknown function (DUF1858)
EFBHDGAE_01935 3.62e-72 yitW - - S - - - Iron-sulfur cluster assembly protein
EFBHDGAE_01936 7.35e-291 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EFBHDGAE_01937 4.31e-182 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
EFBHDGAE_01938 1.2e-217 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFBHDGAE_01939 7.91e-95 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
EFBHDGAE_01940 2.34e-47 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
EFBHDGAE_01941 4.09e-250 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EFBHDGAE_01942 3.28e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Major Facilitator Superfamily
EFBHDGAE_01943 2.36e-77 - - - S - - - Iron-sulfur cluster assembly protein
EFBHDGAE_01944 5.52e-209 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
EFBHDGAE_01945 7.17e-172 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EFBHDGAE_01946 2.84e-240 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EFBHDGAE_01947 8.19e-76 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EFBHDGAE_01948 1.47e-41 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
EFBHDGAE_01949 8.07e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
EFBHDGAE_01950 1.07e-209 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
EFBHDGAE_01952 1.36e-31 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
EFBHDGAE_01953 1.42e-26 B4168_4126 - - L ko:K07493 - ko00000 Transposase
EFBHDGAE_01954 2.05e-166 - - - L - - - PFAM transposase, IS4 family protein
EFBHDGAE_01955 2.35e-243 - - - L - - - Transposase and inactivated derivatives, IS30 family
EFBHDGAE_01956 8.31e-191 B4168_4126 - - L ko:K07493 - ko00000 Transposase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)