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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MEFHIKGN_00001	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MEFHIKGN_00002	3.49e-151	xkdP	-	-	S	-	-	-	Lysin motif
MEFHIKGN_00003	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
MEFHIKGN_00004	6.14e-53	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MEFHIKGN_00005	3.82e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MEFHIKGN_00006	6.23e-244	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MEFHIKGN_00007	2.27e-134	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MEFHIKGN_00008	4.43e-56	-	-	-	-	-	-	-	-
MEFHIKGN_00009	3.53e-224	-	-	-	-	-	-	-	-
MEFHIKGN_00010	1.23e-57	xkdW	-	-	S	-	-	-	XkdW protein
MEFHIKGN_00011	4.47e-31	xkdX	-	-	-	-	-	-	-
MEFHIKGN_00012	3.28e-193	xepA	-	-	-	-	-	-	-
MEFHIKGN_00013	2.21e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
MEFHIKGN_00014	8.12e-53	xhlB	-	-	S	-	-	-	SPP1 phage holin
MEFHIKGN_00015	3.2e-209	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MEFHIKGN_00016	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
MEFHIKGN_00017	4.83e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
MEFHIKGN_00018	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
MEFHIKGN_00019	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
MEFHIKGN_00020	8.98e-310	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MEFHIKGN_00021	8.07e-233	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MEFHIKGN_00022	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEFHIKGN_00023	2.21e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MEFHIKGN_00025	2.41e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MEFHIKGN_00026	4.06e-179	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
MEFHIKGN_00027	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
MEFHIKGN_00028	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEFHIKGN_00029	4.28e-224	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEFHIKGN_00030	1.64e-237	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MEFHIKGN_00031	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MEFHIKGN_00033	8.23e-226	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
MEFHIKGN_00034	1.14e-255	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MEFHIKGN_00035	5.97e-209	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MEFHIKGN_00036	4.88e-236	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MEFHIKGN_00037	1.34e-259	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
MEFHIKGN_00038	2.53e-205	ykgA	-	-	E	-	-	-	Amidinotransferase
MEFHIKGN_00039	1.55e-119	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
MEFHIKGN_00040	1.53e-288	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MEFHIKGN_00041	3.55e-14	-	-	-	-	-	-	-	-
MEFHIKGN_00042	6.55e-166	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
MEFHIKGN_00043	1.57e-128	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
MEFHIKGN_00044	1.46e-127	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MEFHIKGN_00045	1.27e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MEFHIKGN_00046	1.36e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MEFHIKGN_00047	5.81e-218	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MEFHIKGN_00048	3.68e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEFHIKGN_00049	1.6e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MEFHIKGN_00050	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MEFHIKGN_00051	1.66e-96	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
MEFHIKGN_00052	4.72e-93	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MEFHIKGN_00053	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
MEFHIKGN_00054	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MEFHIKGN_00055	1.49e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MEFHIKGN_00056	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MEFHIKGN_00057	2.2e-174	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MEFHIKGN_00058	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_00059	1.14e-126	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MEFHIKGN_00060	1.21e-142	ykoF	-	-	S	-	-	-	YKOF-related Family
MEFHIKGN_00061	1.28e-160	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEFHIKGN_00062	3.5e-306	ykoH	-	-	T	-	-	-	Histidine kinase
MEFHIKGN_00063	4.56e-144	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MEFHIKGN_00064	1.3e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MEFHIKGN_00065	1.45e-08	-	-	-	-	-	-	-	-
MEFHIKGN_00067	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
MEFHIKGN_00068	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
MEFHIKGN_00069	3.3e-25	-	-	-	-	-	-	-	-
MEFHIKGN_00070	3.04e-36	ykoL	-	-	-	-	-	-	-
MEFHIKGN_00071	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MEFHIKGN_00072	1.89e-278	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MEFHIKGN_00073	1.44e-128	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
MEFHIKGN_00074	5.08e-197	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MEFHIKGN_00075	0.0	ykoS	-	-	-	-	-	-	-
MEFHIKGN_00076	9.49e-238	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
MEFHIKGN_00077	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
MEFHIKGN_00078	1.25e-204	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MEFHIKGN_00079	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
MEFHIKGN_00080	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
MEFHIKGN_00081	4.63e-227	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MEFHIKGN_00082	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEFHIKGN_00083	2.19e-217	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
MEFHIKGN_00084	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
MEFHIKGN_00085	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
MEFHIKGN_00086	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MEFHIKGN_00087	4.28e-309	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
MEFHIKGN_00089	1.77e-28	ykzE	-	-	-	-	-	-	-
MEFHIKGN_00090	3.34e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
MEFHIKGN_00091	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_00092	7.91e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MEFHIKGN_00094	3.8e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MEFHIKGN_00095	2.47e-293	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MEFHIKGN_00096	3.86e-191	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MEFHIKGN_00097	6.84e-296	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MEFHIKGN_00098	4.62e-293	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MEFHIKGN_00099	1.77e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MEFHIKGN_00100	7.5e-146	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MEFHIKGN_00101	8.7e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MEFHIKGN_00102	3.6e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
MEFHIKGN_00104	5.84e-95	eag	-	-	-	-	-	-	-
MEFHIKGN_00105	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MEFHIKGN_00106	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MEFHIKGN_00107	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MEFHIKGN_00108	1.65e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MEFHIKGN_00109	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MEFHIKGN_00110	4.76e-227	ykvI	-	-	S	-	-	-	membrane
MEFHIKGN_00111	1.11e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MEFHIKGN_00112	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
MEFHIKGN_00113	2.06e-178	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MEFHIKGN_00114	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MEFHIKGN_00115	2.8e-81	ykvN	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_00116	9.35e-173	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MEFHIKGN_00117	4.27e-272	-	-	-	M	-	-	-	Glycosyl transferases group 1
MEFHIKGN_00118	1.07e-47	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
MEFHIKGN_00119	4.3e-205	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
MEFHIKGN_00120	2.2e-61	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
MEFHIKGN_00121	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_00122	2.6e-39	-	-	-	-	-	-	-	-
MEFHIKGN_00123	5.26e-141	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
MEFHIKGN_00124	1.12e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MEFHIKGN_00125	2.76e-115	stoA	-	-	CO	-	-	-	thiol-disulfide
MEFHIKGN_00126	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MEFHIKGN_00127	3.99e-09	-	-	-	-	-	-	-	-
MEFHIKGN_00128	1.58e-263	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MEFHIKGN_00129	1.33e-229	ykvZ	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_00131	6.87e-168	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
MEFHIKGN_00132	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MEFHIKGN_00133	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
MEFHIKGN_00134	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEFHIKGN_00135	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_00136	2.13e-257	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
MEFHIKGN_00137	1.92e-153	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEFHIKGN_00138	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MEFHIKGN_00139	1.4e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MEFHIKGN_00140	5.36e-172	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
MEFHIKGN_00141	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MEFHIKGN_00142	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_00143	1.4e-281	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MEFHIKGN_00144	1.05e-22	-	-	-	-	-	-	-	-
MEFHIKGN_00145	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
MEFHIKGN_00146	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
MEFHIKGN_00147	3.62e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_00148	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_00149	3.48e-212	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
MEFHIKGN_00150	2.6e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEFHIKGN_00151	0.0	ybfG	-	-	M	-	-	-	Putative peptidoglycan binding domain
MEFHIKGN_00153	1.76e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
MEFHIKGN_00154	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_00155	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
MEFHIKGN_00156	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
MEFHIKGN_00157	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
MEFHIKGN_00158	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_00159	2.59e-112	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
MEFHIKGN_00160	2.89e-221	ykuO	-	-	-	-	-	-	-
MEFHIKGN_00161	2.95e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MEFHIKGN_00162	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MEFHIKGN_00163	7.66e-274	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MEFHIKGN_00164	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
MEFHIKGN_00165	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
MEFHIKGN_00166	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
MEFHIKGN_00167	1.47e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
MEFHIKGN_00168	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
MEFHIKGN_00169	3.45e-200	yknT	-	-	-	ko:K06437	-	ko00000	-
MEFHIKGN_00170	4.38e-140	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MEFHIKGN_00171	5.12e-243	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MEFHIKGN_00172	1.05e-313	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
MEFHIKGN_00173	4.89e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
MEFHIKGN_00174	3.83e-109	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
MEFHIKGN_00175	6.92e-45	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MEFHIKGN_00176	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MEFHIKGN_00177	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MEFHIKGN_00178	1.6e-151	yknW	-	-	S	-	-	-	Yip1 domain
MEFHIKGN_00179	2.34e-233	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MEFHIKGN_00180	6.1e-160	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_00181	1.92e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MEFHIKGN_00182	7.41e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_00183	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
MEFHIKGN_00184	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MEFHIKGN_00185	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MEFHIKGN_00186	4.47e-51	ykoA	-	-	-	-	-	-	-
MEFHIKGN_00187	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MEFHIKGN_00188	1.17e-214	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEFHIKGN_00189	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
MEFHIKGN_00190	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
MEFHIKGN_00191	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
MEFHIKGN_00192	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
MEFHIKGN_00193	4.59e-307	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MEFHIKGN_00194	3.42e-198	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
MEFHIKGN_00195	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MEFHIKGN_00196	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MEFHIKGN_00197	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEFHIKGN_00198	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MEFHIKGN_00199	2.03e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
MEFHIKGN_00200	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEFHIKGN_00201	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MEFHIKGN_00202	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
MEFHIKGN_00203	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MEFHIKGN_00204	1.75e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MEFHIKGN_00205	1.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEFHIKGN_00206	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MEFHIKGN_00207	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
MEFHIKGN_00208	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
MEFHIKGN_00209	1.34e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MEFHIKGN_00210	1.3e-152	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
MEFHIKGN_00211	4.48e-35	ykzI	-	-	-	-	-	-	-
MEFHIKGN_00212	9.48e-195	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
MEFHIKGN_00213	1.48e-100	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
MEFHIKGN_00214	2.88e-220	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MEFHIKGN_00215	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MEFHIKGN_00216	0.0	ylaA	-	-	-	-	-	-	-
MEFHIKGN_00217	1.44e-56	ylaB	-	-	-	-	-	-	-
MEFHIKGN_00218	4.51e-118	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MEFHIKGN_00220	1.74e-57	ylaE	-	-	-	-	-	-	-
MEFHIKGN_00221	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
MEFHIKGN_00222	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MEFHIKGN_00223	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
MEFHIKGN_00224	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_00225	2.97e-127	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MEFHIKGN_00226	3.76e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
MEFHIKGN_00227	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MEFHIKGN_00228	4.25e-220	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MEFHIKGN_00229	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
MEFHIKGN_00230	2.11e-272	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MEFHIKGN_00231	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MEFHIKGN_00232	5.74e-212	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MEFHIKGN_00233	4.88e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MEFHIKGN_00234	2.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MEFHIKGN_00235	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MEFHIKGN_00236	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MEFHIKGN_00237	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MEFHIKGN_00238	8.54e-214	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
MEFHIKGN_00239	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
MEFHIKGN_00240	3.09e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
MEFHIKGN_00241	1.53e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
MEFHIKGN_00242	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
MEFHIKGN_00243	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
MEFHIKGN_00244	4.73e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
MEFHIKGN_00245	5.1e-51	ylbG	-	-	S	-	-	-	UPF0298 protein
MEFHIKGN_00246	7.09e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
MEFHIKGN_00247	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MEFHIKGN_00248	5.5e-282	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
MEFHIKGN_00249	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MEFHIKGN_00250	4.52e-238	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MEFHIKGN_00251	9.84e-300	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MEFHIKGN_00253	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
MEFHIKGN_00254	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MEFHIKGN_00255	3.87e-106	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MEFHIKGN_00256	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
MEFHIKGN_00257	3.22e-214	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEFHIKGN_00258	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MEFHIKGN_00259	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MEFHIKGN_00260	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MEFHIKGN_00261	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
MEFHIKGN_00262	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MEFHIKGN_00263	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
MEFHIKGN_00264	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEFHIKGN_00265	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MEFHIKGN_00266	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MEFHIKGN_00267	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MEFHIKGN_00268	4.66e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MEFHIKGN_00269	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
MEFHIKGN_00270	1.18e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MEFHIKGN_00271	4.5e-142	ylxW	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_00272	1.03e-123	ylxX	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_00273	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
MEFHIKGN_00274	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MEFHIKGN_00275	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEFHIKGN_00276	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
MEFHIKGN_00277	1.06e-220	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MEFHIKGN_00278	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEFHIKGN_00279	1.14e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEFHIKGN_00280	1.57e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MEFHIKGN_00281	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
MEFHIKGN_00282	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
MEFHIKGN_00283	7.53e-203	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
MEFHIKGN_00284	3.15e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MEFHIKGN_00285	5.44e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MEFHIKGN_00286	1.74e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
MEFHIKGN_00287	2.03e-176	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
MEFHIKGN_00288	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
MEFHIKGN_00289	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MEFHIKGN_00290	8.21e-71	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MEFHIKGN_00291	6.39e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MEFHIKGN_00292	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MEFHIKGN_00293	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MEFHIKGN_00294	6.15e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
MEFHIKGN_00295	3.46e-212	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MEFHIKGN_00296	9.71e-317	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEFHIKGN_00297	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MEFHIKGN_00298	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
MEFHIKGN_00299	1.57e-184	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MEFHIKGN_00300	2.2e-223	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MEFHIKGN_00301	6.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MEFHIKGN_00302	5.18e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEFHIKGN_00304	4.19e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MEFHIKGN_00305	2.1e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
MEFHIKGN_00306	2.62e-285	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MEFHIKGN_00307	1.59e-141	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MEFHIKGN_00308	1.24e-186	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MEFHIKGN_00309	1.45e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
MEFHIKGN_00310	2.28e-108	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
MEFHIKGN_00311	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MEFHIKGN_00312	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
MEFHIKGN_00313	1.19e-201	yloC	-	-	S	-	-	-	stress-induced protein
MEFHIKGN_00314	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
MEFHIKGN_00315	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MEFHIKGN_00316	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MEFHIKGN_00317	7.28e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MEFHIKGN_00318	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEFHIKGN_00319	2.38e-109	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEFHIKGN_00320	2.21e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MEFHIKGN_00321	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MEFHIKGN_00322	5.3e-264	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MEFHIKGN_00323	1.18e-178	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MEFHIKGN_00324	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MEFHIKGN_00325	3.92e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MEFHIKGN_00326	4.68e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MEFHIKGN_00327	8.13e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MEFHIKGN_00328	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MEFHIKGN_00329	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_00330	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
MEFHIKGN_00331	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MEFHIKGN_00332	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MEFHIKGN_00333	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MEFHIKGN_00334	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MEFHIKGN_00335	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MEFHIKGN_00336	1.31e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MEFHIKGN_00337	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MEFHIKGN_00338	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEFHIKGN_00339	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MEFHIKGN_00340	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MEFHIKGN_00341	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MEFHIKGN_00342	1.67e-114	-	-	-	-	-	-	-	-
MEFHIKGN_00343	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MEFHIKGN_00344	1.96e-308	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MEFHIKGN_00345	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MEFHIKGN_00346	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MEFHIKGN_00347	1.14e-78	ylqD	-	-	S	-	-	-	YlqD protein
MEFHIKGN_00348	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MEFHIKGN_00349	2.41e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MEFHIKGN_00350	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MEFHIKGN_00351	1.2e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MEFHIKGN_00352	1.37e-173	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEFHIKGN_00353	0.0	ylqG	-	-	-	-	-	-	-
MEFHIKGN_00354	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
MEFHIKGN_00355	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MEFHIKGN_00356	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MEFHIKGN_00357	6.53e-218	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
MEFHIKGN_00358	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEFHIKGN_00359	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MEFHIKGN_00360	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
MEFHIKGN_00361	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MEFHIKGN_00362	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MEFHIKGN_00363	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MEFHIKGN_00364	1.62e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MEFHIKGN_00365	7.54e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
MEFHIKGN_00366	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
MEFHIKGN_00367	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
MEFHIKGN_00368	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MEFHIKGN_00369	1.35e-144	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
MEFHIKGN_00370	1.17e-305	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MEFHIKGN_00371	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
MEFHIKGN_00372	5.08e-84	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
MEFHIKGN_00373	3.66e-311	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
MEFHIKGN_00374	2.81e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
MEFHIKGN_00375	1.09e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
MEFHIKGN_00376	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
MEFHIKGN_00377	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MEFHIKGN_00378	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MEFHIKGN_00379	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
MEFHIKGN_00380	7.87e-137	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
MEFHIKGN_00381	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
MEFHIKGN_00382	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
MEFHIKGN_00383	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
MEFHIKGN_00384	2.74e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MEFHIKGN_00385	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MEFHIKGN_00386	5.65e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
MEFHIKGN_00387	1.09e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
MEFHIKGN_00388	1.81e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MEFHIKGN_00389	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
MEFHIKGN_00390	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
MEFHIKGN_00391	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MEFHIKGN_00392	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MEFHIKGN_00393	9.34e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEFHIKGN_00394	6.62e-99	ylxL	-	-	-	-	-	-	-
MEFHIKGN_00395	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MEFHIKGN_00396	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MEFHIKGN_00397	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MEFHIKGN_00398	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MEFHIKGN_00399	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MEFHIKGN_00400	1.36e-177	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MEFHIKGN_00401	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MEFHIKGN_00402	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MEFHIKGN_00403	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MEFHIKGN_00404	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEFHIKGN_00405	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MEFHIKGN_00406	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MEFHIKGN_00407	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
MEFHIKGN_00408	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
MEFHIKGN_00409	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEFHIKGN_00410	7.83e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
MEFHIKGN_00411	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MEFHIKGN_00412	6.04e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MEFHIKGN_00413	1.1e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MEFHIKGN_00414	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MEFHIKGN_00415	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MEFHIKGN_00416	4.33e-234	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
MEFHIKGN_00417	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
MEFHIKGN_00418	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
MEFHIKGN_00419	5.3e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
MEFHIKGN_00420	3.33e-140	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MEFHIKGN_00421	2.76e-246	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MEFHIKGN_00422	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MEFHIKGN_00423	1.57e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEFHIKGN_00424	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEFHIKGN_00425	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
MEFHIKGN_00426	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
MEFHIKGN_00427	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MEFHIKGN_00428	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_00429	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_00430	3.17e-297	albE	-	-	S	-	-	-	Peptidase M16
MEFHIKGN_00431	7.6e-306	ymfH	-	-	S	-	-	-	zinc protease
MEFHIKGN_00432	6.33e-168	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MEFHIKGN_00433	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MEFHIKGN_00434	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
MEFHIKGN_00435	1.76e-176	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
MEFHIKGN_00436	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEFHIKGN_00437	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MEFHIKGN_00438	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEFHIKGN_00439	8.43e-282	pbpX	-	-	V	-	-	-	Beta-lactamase
MEFHIKGN_00440	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MEFHIKGN_00441	6.18e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
MEFHIKGN_00442	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
MEFHIKGN_00443	8.31e-253	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MEFHIKGN_00444	4.64e-275	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MEFHIKGN_00445	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MEFHIKGN_00446	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
MEFHIKGN_00447	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
MEFHIKGN_00448	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MEFHIKGN_00449	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MEFHIKGN_00450	2.93e-92	-	-	-	S	-	-	-	Regulatory protein YrvL
MEFHIKGN_00452	1.13e-126	ymcC	-	-	S	-	-	-	Membrane
MEFHIKGN_00453	3.43e-140	pksA	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_00454	9.47e-166	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
MEFHIKGN_00455	2.17e-207	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MEFHIKGN_00457	3.17e-234	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
MEFHIKGN_00458	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MEFHIKGN_00459	5.46e-51	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
MEFHIKGN_00460	4.36e-303	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEFHIKGN_00461	9.7e-314	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
MEFHIKGN_00462	2.04e-183	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
MEFHIKGN_00463	4.29e-174	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
MEFHIKGN_00464	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MEFHIKGN_00465	0.0	-	-	-	Q	ko:K13612	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MEFHIKGN_00466	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MEFHIKGN_00467	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MEFHIKGN_00468	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
MEFHIKGN_00469	2.39e-295	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MEFHIKGN_00470	5.65e-81	ymzB	-	-	-	-	-	-	-
MEFHIKGN_00471	3.79e-207	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MEFHIKGN_00472	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
MEFHIKGN_00474	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
MEFHIKGN_00475	6.98e-104	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
MEFHIKGN_00476	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
MEFHIKGN_00477	1.21e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MEFHIKGN_00479	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
MEFHIKGN_00480	5.61e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MEFHIKGN_00481	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MEFHIKGN_00482	1.63e-31	-	-	-	-	-	-	-	-
MEFHIKGN_00483	1.2e-30	ymzA	-	-	-	-	-	-	-
MEFHIKGN_00484	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MEFHIKGN_00485	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEFHIKGN_00486	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEFHIKGN_00487	2.24e-141	-	-	-	-	-	-	-	-
MEFHIKGN_00488	2.34e-149	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MEFHIKGN_00489	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
MEFHIKGN_00490	1.82e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MEFHIKGN_00491	5.82e-311	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MEFHIKGN_00492	4.05e-89	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
MEFHIKGN_00493	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MEFHIKGN_00494	4.18e-14	-	-	-	-	-	-	-	-
MEFHIKGN_00496	4.15e-49	-	-	-	-	-	-	-	-
MEFHIKGN_00497	3.26e-113	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
MEFHIKGN_00498	1.1e-24	ynaC	-	-	-	-	-	-	-
MEFHIKGN_00499	5.84e-126	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MEFHIKGN_00501	1.21e-90	-	-	-	S	-	-	-	CAAX protease self-immunity
MEFHIKGN_00503	8.64e-34	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MEFHIKGN_00504	1.28e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
MEFHIKGN_00507	4.15e-108	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
MEFHIKGN_00508	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
MEFHIKGN_00509	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MEFHIKGN_00510	1.44e-274	xylR	-	-	GK	-	-	-	ROK family
MEFHIKGN_00511	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MEFHIKGN_00512	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
MEFHIKGN_00513	2.51e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
MEFHIKGN_00514	3.31e-246	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MEFHIKGN_00515	1.77e-280	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEFHIKGN_00516	3.86e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
MEFHIKGN_00517	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
MEFHIKGN_00518	3.07e-21	-	-	-	-	-	-	-	-
MEFHIKGN_00521	3.75e-208	-	-	-	S	-	-	-	Thymidylate synthase
MEFHIKGN_00523	1.36e-61	-	-	-	S	-	-	-	Domain of unknown function, YrpD
MEFHIKGN_00524	4.12e-96	-	-	-	S	-	-	-	Domain of unknown function, YrpD
MEFHIKGN_00527	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
MEFHIKGN_00528	8.92e-96	-	-	-	-	-	-	-	-
MEFHIKGN_00529	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
MEFHIKGN_00532	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MEFHIKGN_00533	1.95e-250	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
MEFHIKGN_00534	9.64e-290	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MEFHIKGN_00535	5.29e-198	yndG	-	-	S	-	-	-	DoxX-like family
MEFHIKGN_00536	3.46e-149	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
MEFHIKGN_00537	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
MEFHIKGN_00539	5.63e-176	yndL	-	-	S	-	-	-	Replication protein
MEFHIKGN_00540	4.42e-95	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MEFHIKGN_00541	5.34e-97	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MEFHIKGN_00542	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MEFHIKGN_00543	2.44e-64	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MEFHIKGN_00544	5.4e-143	yneB	-	-	L	-	-	-	resolvase
MEFHIKGN_00545	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
MEFHIKGN_00546	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MEFHIKGN_00547	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
MEFHIKGN_00548	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
MEFHIKGN_00549	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MEFHIKGN_00550	1.68e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
MEFHIKGN_00551	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
MEFHIKGN_00552	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
MEFHIKGN_00553	3.97e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
MEFHIKGN_00554	5.77e-85	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
MEFHIKGN_00555	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
MEFHIKGN_00556	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
MEFHIKGN_00557	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MEFHIKGN_00558	3.74e-120	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MEFHIKGN_00559	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
MEFHIKGN_00561	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
MEFHIKGN_00562	5.7e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
MEFHIKGN_00563	9.46e-71	yneQ	-	-	-	-	-	-	-
MEFHIKGN_00564	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MEFHIKGN_00565	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MEFHIKGN_00566	1.72e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
MEFHIKGN_00567	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEFHIKGN_00568	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEFHIKGN_00569	1.82e-18	-	-	-	-	-	-	-	-
MEFHIKGN_00570	1.06e-75	ynfC	-	-	-	-	-	-	-
MEFHIKGN_00571	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MEFHIKGN_00572	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
MEFHIKGN_00574	1.18e-315	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
MEFHIKGN_00575	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MEFHIKGN_00576	1.72e-103	yngA	-	-	S	-	-	-	membrane
MEFHIKGN_00577	2.74e-210	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MEFHIKGN_00578	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
MEFHIKGN_00579	1.82e-296	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
MEFHIKGN_00580	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MEFHIKGN_00581	1.42e-173	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
MEFHIKGN_00582	1.36e-211	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
MEFHIKGN_00583	2.4e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
MEFHIKGN_00584	1.87e-316	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
MEFHIKGN_00585	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MEFHIKGN_00586	3.09e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MEFHIKGN_00587	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
MEFHIKGN_00588	1.01e-82	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MEFHIKGN_00589	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
MEFHIKGN_00590	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEFHIKGN_00591	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEFHIKGN_00592	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEFHIKGN_00593	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEFHIKGN_00594	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MEFHIKGN_00595	1.92e-240	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MEFHIKGN_00596	9.8e-313	yoeA	-	-	V	-	-	-	MATE efflux family protein
MEFHIKGN_00597	7.14e-128	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
MEFHIKGN_00599	1.14e-124	-	-	-	L	-	-	-	Integrase
MEFHIKGN_00600	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
MEFHIKGN_00601	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MEFHIKGN_00602	1.3e-202	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_00603	1.7e-236	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MEFHIKGN_00604	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MEFHIKGN_00605	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
MEFHIKGN_00606	2.14e-204	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_00607	2.72e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEFHIKGN_00608	2.72e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEFHIKGN_00609	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MEFHIKGN_00610	1.47e-155	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFHIKGN_00611	9.05e-52	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
MEFHIKGN_00612	1.58e-167	yoxB	-	-	-	-	-	-	-
MEFHIKGN_00613	5.23e-119	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MEFHIKGN_00614	4.18e-166	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MEFHIKGN_00615	1.77e-121	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MEFHIKGN_00616	7.07e-177	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MEFHIKGN_00617	4.72e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MEFHIKGN_00618	3.04e-298	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
MEFHIKGN_00619	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MEFHIKGN_00620	3.36e-234	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEFHIKGN_00621	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MEFHIKGN_00622	7.24e-45	yoaF	-	-	-	-	-	-	-
MEFHIKGN_00624	1.25e-20	-	-	-	-	-	-	-	-
MEFHIKGN_00625	8.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
MEFHIKGN_00626	0.0	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
MEFHIKGN_00627	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
MEFHIKGN_00628	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
MEFHIKGN_00629	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
MEFHIKGN_00630	3.38e-251	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
MEFHIKGN_00631	4.18e-170	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
MEFHIKGN_00633	3.1e-293	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MEFHIKGN_00636	1.08e-112	-	-	-	-	-	-	-	-
MEFHIKGN_00637	1.48e-217	yoaR	-	-	V	-	-	-	vancomycin resistance protein
MEFHIKGN_00638	2.65e-97	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
MEFHIKGN_00639	7.19e-41	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_00640	1.57e-188	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
MEFHIKGN_00641	6.67e-203	yoaU	-	-	K	-	-	-	LysR substrate binding domain
MEFHIKGN_00642	1.83e-201	yoaV	-	-	EG	-	-	-	EamA-like transporter family
MEFHIKGN_00643	5.63e-102	yoaW	-	-	-	-	-	-	-
MEFHIKGN_00644	2.07e-148	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
MEFHIKGN_00645	9.93e-213	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
MEFHIKGN_00648	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
MEFHIKGN_00649	7.53e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
MEFHIKGN_00651	6.27e-51	-	-	-	S	-	-	-	TM2 domain
MEFHIKGN_00652	1.87e-74	-	-	-	K	-	-	-	Helix-turn-helix
MEFHIKGN_00654	1.54e-84	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
MEFHIKGN_00655	1.48e-30	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
MEFHIKGN_00656	2.71e-29	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEFHIKGN_00657	2.59e-220	-	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
MEFHIKGN_00658	3.14e-167	-	-	-	K	-	-	-	Bacterial regulatory proteins, lacI family
MEFHIKGN_00659	1.23e-272	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
MEFHIKGN_00661	5.09e-53	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MEFHIKGN_00662	2.16e-128	-	-	-	P	ko:K02026,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MEFHIKGN_00663	1.33e-141	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEFHIKGN_00664	0.0	aga	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha-galactosidase
MEFHIKGN_00665	1.09e-134	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MEFHIKGN_00666	2.24e-110	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
MEFHIKGN_00667	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MEFHIKGN_00668	1.14e-131	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
MEFHIKGN_00669	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
MEFHIKGN_00670	1.82e-71	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
MEFHIKGN_00671	6.36e-172	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MEFHIKGN_00672	4.16e-180	-	-	-	J	-	-	-	FR47-like protein
MEFHIKGN_00673	4.91e-124	yobS	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_00674	1.29e-167	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MEFHIKGN_00675	8.64e-112	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
MEFHIKGN_00676	5.41e-225	yobV	-	-	K	-	-	-	WYL domain
MEFHIKGN_00677	3.01e-120	yobW	-	-	-	-	-	-	-
MEFHIKGN_00678	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
MEFHIKGN_00679	3.28e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MEFHIKGN_00680	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
MEFHIKGN_00681	2.6e-185	-	-	-	-	-	-	-	-
MEFHIKGN_00682	1.8e-120	yocC	-	-	-	-	-	-	-
MEFHIKGN_00683	3.88e-240	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
MEFHIKGN_00684	3.28e-257	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MEFHIKGN_00685	3.51e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_00686	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEFHIKGN_00687	2.89e-175	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
MEFHIKGN_00688	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MEFHIKGN_00690	8.45e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MEFHIKGN_00691	4.07e-107	yocK	-	-	T	-	-	-	general stress protein
MEFHIKGN_00692	3.02e-70	yocL	-	-	-	-	-	-	-
MEFHIKGN_00693	7.29e-46	-	-	-	-	-	-	-	-
MEFHIKGN_00694	6.6e-115	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MEFHIKGN_00695	2.94e-55	yozN	-	-	-	-	-	-	-
MEFHIKGN_00696	1.83e-49	yocN	-	-	-	-	-	-	-
MEFHIKGN_00697	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
MEFHIKGN_00698	1.91e-42	yozC	-	-	-	-	-	-	-
MEFHIKGN_00699	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MEFHIKGN_00700	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
MEFHIKGN_00701	3.91e-211	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
MEFHIKGN_00702	3.57e-299	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MEFHIKGN_00703	3.31e-214	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
MEFHIKGN_00704	3.02e-263	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MEFHIKGN_00705	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MEFHIKGN_00706	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
MEFHIKGN_00707	2.69e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
MEFHIKGN_00708	6.01e-141	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MEFHIKGN_00709	1.3e-267	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MEFHIKGN_00710	5.62e-294	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
MEFHIKGN_00711	3.69e-142	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MEFHIKGN_00713	5.06e-314	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
MEFHIKGN_00714	2.49e-194	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MEFHIKGN_00715	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
MEFHIKGN_00716	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
MEFHIKGN_00717	3.74e-58	-	-	-	-	-	-	-	-
MEFHIKGN_00718	2e-208	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
MEFHIKGN_00719	7.43e-107	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
MEFHIKGN_00720	5.59e-14	-	-	-	-	-	-	-	-
MEFHIKGN_00721	2.65e-289	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MEFHIKGN_00722	5.64e-84	iolK	-	-	S	-	-	-	tautomerase
MEFHIKGN_00723	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
MEFHIKGN_00724	4.53e-139	yodC	-	-	C	-	-	-	nitroreductase
MEFHIKGN_00725	1.31e-146	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
MEFHIKGN_00726	1.38e-222	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MEFHIKGN_00727	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MEFHIKGN_00728	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEFHIKGN_00729	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MEFHIKGN_00730	3.69e-167	yodH	-	-	Q	-	-	-	Methyltransferase
MEFHIKGN_00731	2.93e-42	yodI	-	-	-	-	-	-	-
MEFHIKGN_00732	1.33e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
MEFHIKGN_00733	1.19e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MEFHIKGN_00734	2.08e-12	-	-	-	-	-	-	-	-
MEFHIKGN_00735	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
MEFHIKGN_00736	1.91e-136	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MEFHIKGN_00737	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
MEFHIKGN_00739	1.29e-159	yodN	-	-	-	-	-	-	-
MEFHIKGN_00740	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MEFHIKGN_00741	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
MEFHIKGN_00742	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
MEFHIKGN_00743	1.84e-197	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
MEFHIKGN_00744	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
MEFHIKGN_00745	4.49e-151	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MEFHIKGN_00746	3.41e-161	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MEFHIKGN_00747	0.0	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MEFHIKGN_00749	1.56e-181	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
MEFHIKGN_00750	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
MEFHIKGN_00751	1.76e-58	cgeC	-	-	-	ko:K06321	-	ko00000	-
MEFHIKGN_00752	5.57e-86	cgeA	-	-	-	ko:K06319	-	ko00000	-
MEFHIKGN_00753	3.86e-236	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
MEFHIKGN_00754	1.39e-280	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
MEFHIKGN_00755	1.66e-157	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MEFHIKGN_00756	7.13e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MEFHIKGN_00757	9.83e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEFHIKGN_00758	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
MEFHIKGN_00759	5.77e-289	mepA	-	-	V	-	-	-	MATE efflux family protein
MEFHIKGN_00760	2.13e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
MEFHIKGN_00761	1.95e-128	ypmS	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_00762	1.28e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MEFHIKGN_00763	3.23e-139	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MEFHIKGN_00764	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
MEFHIKGN_00765	1.04e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MEFHIKGN_00766	1.4e-236	yplP	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_00767	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
MEFHIKGN_00768	8.12e-144	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MEFHIKGN_00769	9.58e-122	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MEFHIKGN_00770	2.34e-199	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEFHIKGN_00771	8.91e-121	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MEFHIKGN_00772	3.47e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
MEFHIKGN_00773	2.92e-185	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
MEFHIKGN_00774	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
MEFHIKGN_00775	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
MEFHIKGN_00776	8.52e-206	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
MEFHIKGN_00777	3.3e-138	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MEFHIKGN_00778	3.13e-114	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
MEFHIKGN_00779	1.28e-226	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MEFHIKGN_00780	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MEFHIKGN_00781	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MEFHIKGN_00782	1.17e-22	degR	-	-	-	-	-	-	-
MEFHIKGN_00783	3.02e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
MEFHIKGN_00784	7.99e-41	ypeQ	-	-	S	-	-	-	Zinc-finger
MEFHIKGN_00785	1.1e-160	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
MEFHIKGN_00786	6.59e-136	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MEFHIKGN_00787	7.64e-88	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
MEFHIKGN_00788	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
MEFHIKGN_00789	7.58e-212	ypcP	-	-	L	-	-	-	5'3' exonuclease
MEFHIKGN_00790	1.08e-11	-	-	-	-	-	-	-	-
MEFHIKGN_00791	1.17e-51	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
MEFHIKGN_00792	0.0	ypbR	-	-	S	-	-	-	Dynamin family
MEFHIKGN_00793	3.33e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
MEFHIKGN_00794	7.54e-265	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
MEFHIKGN_00795	8.61e-292	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
MEFHIKGN_00796	8.16e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MEFHIKGN_00797	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MEFHIKGN_00798	3.35e-223	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MEFHIKGN_00799	1.03e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
MEFHIKGN_00800	6.95e-238	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
MEFHIKGN_00801	1.19e-234	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
MEFHIKGN_00802	1.2e-202	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MEFHIKGN_00803	4.44e-174	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEFHIKGN_00804	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
MEFHIKGN_00806	9.72e-66	yqgA	-	-	-	-	-	-	-
MEFHIKGN_00807	4.8e-275	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MEFHIKGN_00808	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MEFHIKGN_00809	1.28e-125	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MEFHIKGN_00810	1.63e-297	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
MEFHIKGN_00811	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MEFHIKGN_00812	1.58e-111	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
MEFHIKGN_00813	2.06e-93	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MEFHIKGN_00814	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
MEFHIKGN_00815	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
MEFHIKGN_00816	7.9e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
MEFHIKGN_00819	5.3e-240	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
MEFHIKGN_00820	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MEFHIKGN_00821	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MEFHIKGN_00822	1.17e-120	ypoC	-	-	-	-	-	-	-
MEFHIKGN_00823	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MEFHIKGN_00824	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
MEFHIKGN_00825	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
MEFHIKGN_00826	4.37e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MEFHIKGN_00827	2.27e-103	ypmB	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_00828	6.21e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
MEFHIKGN_00829	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MEFHIKGN_00830	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MEFHIKGN_00831	7.78e-200	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MEFHIKGN_00832	4.85e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MEFHIKGN_00833	6.91e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MEFHIKGN_00834	1.41e-283	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MEFHIKGN_00835	8.54e-268	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
MEFHIKGN_00836	6.61e-167	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
MEFHIKGN_00837	1.52e-94	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
MEFHIKGN_00838	2.4e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MEFHIKGN_00839	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
MEFHIKGN_00840	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MEFHIKGN_00841	2.79e-182	ypjB	-	-	S	-	-	-	sporulation protein
MEFHIKGN_00842	2.82e-126	ypjA	-	-	S	-	-	-	membrane
MEFHIKGN_00843	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
MEFHIKGN_00844	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
MEFHIKGN_00845	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
MEFHIKGN_00846	2.75e-100	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
MEFHIKGN_00847	1.83e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
MEFHIKGN_00848	2.92e-296	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
MEFHIKGN_00849	4.03e-301	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MEFHIKGN_00850	4.03e-263	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MEFHIKGN_00851	1.5e-257	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MEFHIKGN_00852	1.56e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MEFHIKGN_00853	6.3e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MEFHIKGN_00854	3.04e-148	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
MEFHIKGN_00855	4.18e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
MEFHIKGN_00856	6.08e-230	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MEFHIKGN_00857	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MEFHIKGN_00858	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MEFHIKGN_00859	4.7e-262	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MEFHIKGN_00860	1.44e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MEFHIKGN_00861	5.24e-183	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
MEFHIKGN_00862	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MEFHIKGN_00863	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MEFHIKGN_00864	1.34e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MEFHIKGN_00865	8.72e-178	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MEFHIKGN_00866	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MEFHIKGN_00867	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MEFHIKGN_00868	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEFHIKGN_00869	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MEFHIKGN_00870	8.71e-176	yphF	-	-	-	-	-	-	-
MEFHIKGN_00871	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
MEFHIKGN_00872	6.32e-231	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MEFHIKGN_00873	4.77e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MEFHIKGN_00874	8.69e-40	ypzH	-	-	-	-	-	-	-
MEFHIKGN_00875	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
MEFHIKGN_00876	2.73e-134	yphA	-	-	-	-	-	-	-
MEFHIKGN_00877	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
MEFHIKGN_00878	8.41e-238	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MEFHIKGN_00879	9.5e-263	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MEFHIKGN_00880	1.73e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MEFHIKGN_00881	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
MEFHIKGN_00882	4.63e-144	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
MEFHIKGN_00883	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
MEFHIKGN_00884	4.88e-208	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
MEFHIKGN_00885	4.33e-154	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
MEFHIKGN_00886	1.62e-227	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
MEFHIKGN_00887	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MEFHIKGN_00888	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MEFHIKGN_00889	1.02e-186	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MEFHIKGN_00890	1.42e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
MEFHIKGN_00891	7.22e-137	ypbE	-	-	M	-	-	-	Lysin motif
MEFHIKGN_00892	3.55e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
MEFHIKGN_00893	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MEFHIKGN_00894	5.67e-258	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
MEFHIKGN_00895	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
MEFHIKGN_00896	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MEFHIKGN_00897	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEFHIKGN_00898	1.95e-173	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MEFHIKGN_00899	4.99e-253	rsiX	-	-	-	-	-	-	-
MEFHIKGN_00900	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MEFHIKGN_00901	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_00902	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEFHIKGN_00903	1.34e-278	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MEFHIKGN_00904	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
MEFHIKGN_00905	1.5e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MEFHIKGN_00906	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MEFHIKGN_00907	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
MEFHIKGN_00908	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
MEFHIKGN_00909	1.18e-272	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MEFHIKGN_00910	6.13e-128	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
MEFHIKGN_00911	2e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MEFHIKGN_00912	1.33e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MEFHIKGN_00913	5.92e-119	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
MEFHIKGN_00914	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEFHIKGN_00915	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MEFHIKGN_00916	1.8e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MEFHIKGN_00917	1.24e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MEFHIKGN_00918	7.21e-261	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MEFHIKGN_00919	1.41e-70	ypuD	-	-	-	-	-	-	-
MEFHIKGN_00920	1.18e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MEFHIKGN_00921	1.28e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
MEFHIKGN_00922	1.61e-16	-	-	-	S	-	-	-	SNARE associated Golgi protein
MEFHIKGN_00924	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEFHIKGN_00925	3.12e-192	ypuA	-	-	S	-	-	-	Secreted protein
MEFHIKGN_00926	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MEFHIKGN_00927	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
MEFHIKGN_00928	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MEFHIKGN_00929	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MEFHIKGN_00930	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
MEFHIKGN_00931	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
MEFHIKGN_00932	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
MEFHIKGN_00933	5.72e-144	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
MEFHIKGN_00934	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEFHIKGN_00935	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MEFHIKGN_00936	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
MEFHIKGN_00937	2.89e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MEFHIKGN_00938	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MEFHIKGN_00939	2.89e-295	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MEFHIKGN_00940	3.91e-214	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
MEFHIKGN_00941	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
MEFHIKGN_00942	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MEFHIKGN_00943	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MEFHIKGN_00944	1.72e-40	yqkK	-	-	-	-	-	-	-
MEFHIKGN_00945	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MEFHIKGN_00946	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MEFHIKGN_00947	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
MEFHIKGN_00948	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
MEFHIKGN_00949	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_00950	6.16e-282	yqxK	-	-	L	-	-	-	DNA helicase
MEFHIKGN_00951	1.17e-119	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
MEFHIKGN_00952	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
MEFHIKGN_00953	3.61e-215	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MEFHIKGN_00954	6.61e-26	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
MEFHIKGN_00955	1.38e-223	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MEFHIKGN_00956	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
MEFHIKGN_00957	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
MEFHIKGN_00958	9.27e-248	yqkA	-	-	K	-	-	-	GrpB protein
MEFHIKGN_00959	6.44e-78	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
MEFHIKGN_00960	3.16e-112	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MEFHIKGN_00961	5.37e-65	yqiX	-	-	S	-	-	-	YolD-like protein
MEFHIKGN_00962	4.9e-303	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEFHIKGN_00964	2.04e-289	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
MEFHIKGN_00966	1.28e-93	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEFHIKGN_00967	6.6e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MEFHIKGN_00968	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
MEFHIKGN_00969	6.89e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFHIKGN_00970	3.14e-227	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MEFHIKGN_00971	1.13e-188	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEFHIKGN_00972	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MEFHIKGN_00973	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MEFHIKGN_00974	6.4e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MEFHIKGN_00975	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MEFHIKGN_00976	7.66e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MEFHIKGN_00977	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MEFHIKGN_00978	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MEFHIKGN_00979	7.8e-301	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEFHIKGN_00980	1.77e-32	yqzJ	-	-	-	-	-	-	-
MEFHIKGN_00981	3.36e-184	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEFHIKGN_00982	6.93e-181	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
MEFHIKGN_00983	1.76e-257	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
MEFHIKGN_00984	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MEFHIKGN_00985	4.67e-95	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
MEFHIKGN_00987	2.41e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_00988	1.88e-225	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
MEFHIKGN_00989	1.28e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MEFHIKGN_00990	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MEFHIKGN_00991	1.43e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MEFHIKGN_00992	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
MEFHIKGN_00993	1.65e-211	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MEFHIKGN_00994	3.09e-267	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_00995	4.97e-175	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
MEFHIKGN_00996	1.95e-290	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEFHIKGN_00997	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MEFHIKGN_00998	2.24e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MEFHIKGN_00999	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MEFHIKGN_01000	1.96e-254	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
MEFHIKGN_01001	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MEFHIKGN_01002	1.74e-198	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
MEFHIKGN_01003	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
MEFHIKGN_01004	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
MEFHIKGN_01005	7.23e-208	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MEFHIKGN_01006	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
MEFHIKGN_01007	4.75e-267	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MEFHIKGN_01008	5.16e-270	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
MEFHIKGN_01009	4.16e-200	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
MEFHIKGN_01010	1.34e-279	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MEFHIKGN_01011	4.29e-171	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MEFHIKGN_01012	5.67e-139	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
MEFHIKGN_01013	4.74e-37	-	-	-	-	-	-	-	-
MEFHIKGN_01014	1.54e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MEFHIKGN_01016	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MEFHIKGN_01017	1.47e-302	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
MEFHIKGN_01018	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MEFHIKGN_01019	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MEFHIKGN_01020	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
MEFHIKGN_01021	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEFHIKGN_01022	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MEFHIKGN_01023	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEFHIKGN_01024	3.55e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEFHIKGN_01025	1.07e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MEFHIKGN_01026	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MEFHIKGN_01027	1.65e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_01028	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MEFHIKGN_01029	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MEFHIKGN_01030	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
MEFHIKGN_01031	1.08e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
MEFHIKGN_01032	2.58e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
MEFHIKGN_01033	7.65e-257	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
MEFHIKGN_01034	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
MEFHIKGN_01035	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
MEFHIKGN_01036	5.69e-111	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
MEFHIKGN_01037	2.02e-217	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
MEFHIKGN_01038	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
MEFHIKGN_01039	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEFHIKGN_01040	2.99e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MEFHIKGN_01041	1.17e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
MEFHIKGN_01042	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
MEFHIKGN_01043	5.16e-221	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
MEFHIKGN_01044	5.18e-81	yqhP	-	-	-	-	-	-	-
MEFHIKGN_01045	5.75e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MEFHIKGN_01046	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MEFHIKGN_01047	9.17e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MEFHIKGN_01048	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
MEFHIKGN_01049	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MEFHIKGN_01050	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MEFHIKGN_01051	1.35e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
MEFHIKGN_01052	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MEFHIKGN_01053	9.14e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
MEFHIKGN_01054	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
MEFHIKGN_01055	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
MEFHIKGN_01056	1.49e-180	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
MEFHIKGN_01057	7.4e-98	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
MEFHIKGN_01058	1.76e-159	yqxM	-	-	-	ko:K19433	-	ko00000	-
MEFHIKGN_01059	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MEFHIKGN_01060	3.33e-35	yqzE	-	-	S	-	-	-	YqzE-like protein
MEFHIKGN_01061	1.88e-57	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
MEFHIKGN_01062	2.9e-46	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MEFHIKGN_01063	1.77e-78	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
MEFHIKGN_01064	9.7e-94	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
MEFHIKGN_01065	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
MEFHIKGN_01066	1.51e-219	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
MEFHIKGN_01067	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MEFHIKGN_01069	3.73e-09	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
MEFHIKGN_01070	7.17e-232	yqxL	-	-	P	-	-	-	Mg2 transporter protein
MEFHIKGN_01071	5.77e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MEFHIKGN_01072	2.49e-192	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MEFHIKGN_01074	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
MEFHIKGN_01075	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
MEFHIKGN_01076	1.07e-155	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
MEFHIKGN_01077	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
MEFHIKGN_01078	8.58e-65	yqgV	-	-	S	-	-	-	Thiamine-binding protein
MEFHIKGN_01079	3.27e-257	yqgU	-	-	-	-	-	-	-
MEFHIKGN_01080	3.04e-283	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
MEFHIKGN_01081	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MEFHIKGN_01082	2.81e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MEFHIKGN_01083	9.15e-45	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
MEFHIKGN_01084	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
MEFHIKGN_01085	3.38e-14	yqgO	-	-	-	-	-	-	-
MEFHIKGN_01086	3.8e-135	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MEFHIKGN_01087	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MEFHIKGN_01088	2.81e-257	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
MEFHIKGN_01090	2.81e-67	yqzD	-	-	-	-	-	-	-
MEFHIKGN_01091	1.09e-93	yqzC	-	-	S	-	-	-	YceG-like family
MEFHIKGN_01092	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEFHIKGN_01093	2.4e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEFHIKGN_01094	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MEFHIKGN_01095	1.43e-202	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MEFHIKGN_01096	2.14e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MEFHIKGN_01097	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MEFHIKGN_01098	1.32e-291	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
MEFHIKGN_01099	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
MEFHIKGN_01100	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
MEFHIKGN_01101	1.87e-171	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MEFHIKGN_01102	2.05e-99	yqgA	-	-	-	-	-	-	-
MEFHIKGN_01103	2.84e-63	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
MEFHIKGN_01104	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MEFHIKGN_01105	2.04e-81	yqfX	-	-	S	-	-	-	membrane
MEFHIKGN_01106	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
MEFHIKGN_01107	2.47e-106	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
MEFHIKGN_01108	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MEFHIKGN_01109	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
MEFHIKGN_01110	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MEFHIKGN_01111	4.45e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MEFHIKGN_01112	4.89e-58	yqfQ	-	-	S	-	-	-	YqfQ-like protein
MEFHIKGN_01113	1.75e-226	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MEFHIKGN_01114	3.77e-269	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MEFHIKGN_01115	4.66e-148	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MEFHIKGN_01116	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MEFHIKGN_01117	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MEFHIKGN_01118	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MEFHIKGN_01119	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
MEFHIKGN_01120	1.29e-190	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MEFHIKGN_01121	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
MEFHIKGN_01122	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MEFHIKGN_01123	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MEFHIKGN_01124	7.48e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MEFHIKGN_01125	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
MEFHIKGN_01126	1.42e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MEFHIKGN_01127	2.73e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MEFHIKGN_01128	4.75e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MEFHIKGN_01129	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MEFHIKGN_01130	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
MEFHIKGN_01132	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
MEFHIKGN_01133	9.93e-241	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
MEFHIKGN_01134	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
MEFHIKGN_01135	3.5e-53	yqfB	-	-	-	-	-	-	-
MEFHIKGN_01136	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
MEFHIKGN_01137	7.97e-292	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
MEFHIKGN_01138	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
MEFHIKGN_01139	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MEFHIKGN_01140	4.9e-202	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
MEFHIKGN_01141	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
MEFHIKGN_01142	1.38e-178	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MEFHIKGN_01143	5.63e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
MEFHIKGN_01144	9.76e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MEFHIKGN_01145	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MEFHIKGN_01146	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MEFHIKGN_01147	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MEFHIKGN_01148	1.23e-277	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MEFHIKGN_01149	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEFHIKGN_01150	7.06e-70	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
MEFHIKGN_01151	2.73e-283	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
MEFHIKGN_01152	3.42e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MEFHIKGN_01153	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MEFHIKGN_01154	1.16e-243	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MEFHIKGN_01155	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
MEFHIKGN_01156	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MEFHIKGN_01157	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MEFHIKGN_01158	6.65e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
MEFHIKGN_01159	1.1e-188	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEFHIKGN_01160	2.31e-177	yqeM	-	-	Q	-	-	-	Methyltransferase
MEFHIKGN_01161	1.39e-81	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MEFHIKGN_01162	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
MEFHIKGN_01163	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MEFHIKGN_01164	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
MEFHIKGN_01165	4.01e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MEFHIKGN_01166	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MEFHIKGN_01167	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
MEFHIKGN_01169	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MEFHIKGN_01170	5.41e-173	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MEFHIKGN_01171	3.27e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
MEFHIKGN_01172	7.31e-215	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
MEFHIKGN_01173	9.38e-171	-	-	-	-	-	-	-	-
MEFHIKGN_01174	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MEFHIKGN_01175	8.2e-73	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEFHIKGN_01176	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
MEFHIKGN_01178	7.77e-65	ohrR	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_01179	3.54e-62	ohrB	-	-	O	-	-	-	OsmC-like protein
MEFHIKGN_01180	1.06e-176	-	-	-	I	ko:K01066	-	ko00000,ko01000	esterase
MEFHIKGN_01181	5.51e-121	hrtA	-	-	V	ko:K02003,ko:K09814	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
MEFHIKGN_01182	2.92e-165	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
MEFHIKGN_01183	3.22e-240	-	-	-	T	-	-	-	Histidine kinase
MEFHIKGN_01184	1.76e-122	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEFHIKGN_01186	1.05e-170	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
MEFHIKGN_01187	3.68e-176	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Reductase
MEFHIKGN_01188	1.91e-91	-	-	-	K	-	-	-	MerR family transcriptional regulator
MEFHIKGN_01189	5.7e-287	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MEFHIKGN_01192	9.34e-20	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
MEFHIKGN_01193	1.74e-62	-	-	-	-	-	-	-	-
MEFHIKGN_01194	4.22e-130	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
MEFHIKGN_01197	1.11e-172	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MEFHIKGN_01198	8.36e-89	-	-	-	S	-	-	-	Bacteriophage holin family
MEFHIKGN_01199	5.93e-205	xepA	-	-	-	-	-	-	-
MEFHIKGN_01200	7.59e-21	-	-	-	-	-	-	-	-
MEFHIKGN_01201	1.01e-73	xkdW	-	-	S	-	-	-	XkdW protein
MEFHIKGN_01202	1.89e-279	-	-	-	-	-	-	-	-
MEFHIKGN_01203	3e-54	-	-	-	-	-	-	-	-
MEFHIKGN_01204	8.88e-132	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MEFHIKGN_01205	2.6e-236	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MEFHIKGN_01206	3.52e-86	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MEFHIKGN_01207	2e-42	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MEFHIKGN_01208	5.9e-57	xkdQ	-	-	G	-	-	-	NLP P60 protein
MEFHIKGN_01209	7.76e-106	yqaL	-	-	L	-	-	-	DnaD domain protein
MEFHIKGN_01210	1.88e-190	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
MEFHIKGN_01211	4.4e-220	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
MEFHIKGN_01215	1.04e-133	-	-	-	-	-	-	-	-
MEFHIKGN_01217	2.84e-23	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MEFHIKGN_01218	1.88e-42	-	-	-	K	-	-	-	sequence-specific DNA binding
MEFHIKGN_01219	8.07e-128	yqaC	-	-	F	-	-	-	adenylate kinase activity
MEFHIKGN_01221	1.58e-122	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MEFHIKGN_01222	4.46e-79	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEFHIKGN_01223	1.94e-145	tetR3	-	-	K	ko:K18476	-	ko00000,ko00002,ko03000	Transcriptional regulator
MEFHIKGN_01224	1.17e-181	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	Multidrug transporter MatE
MEFHIKGN_01225	8.7e-71	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	Multidrug transporter MatE
MEFHIKGN_01226	1.26e-207	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
MEFHIKGN_01227	1.15e-162	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MEFHIKGN_01228	1.3e-48	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
MEFHIKGN_01229	4.67e-260	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
MEFHIKGN_01230	1.61e-126	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
MEFHIKGN_01231	3.25e-107	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
MEFHIKGN_01232	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_01233	1.05e-136	yrkC	-	-	G	-	-	-	Cupin domain
MEFHIKGN_01234	3.56e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MEFHIKGN_01235	1.26e-267	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_01236	7.52e-109	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
MEFHIKGN_01237	1.52e-299	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MEFHIKGN_01238	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
MEFHIKGN_01239	1.26e-218	yrdR	-	-	EG	-	-	-	EamA-like transporter family
MEFHIKGN_01240	2.83e-203	-	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_01241	2.48e-253	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
MEFHIKGN_01242	3.68e-206	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
MEFHIKGN_01243	1.01e-86	yodA	-	-	S	-	-	-	tautomerase
MEFHIKGN_01244	4.97e-150	-	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
MEFHIKGN_01245	3.01e-293	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MEFHIKGN_01246	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
MEFHIKGN_01247	9.34e-176	azlC	-	-	E	-	-	-	AzlC protein
MEFHIKGN_01248	4.13e-104	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
MEFHIKGN_01249	4.64e-44	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MEFHIKGN_01250	2.38e-293	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MEFHIKGN_01251	4.27e-132	yrdC	-	-	Q	-	-	-	Isochorismatase family
MEFHIKGN_01252	2.28e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
MEFHIKGN_01253	5.77e-118	yrdA	-	-	S	-	-	-	DinB family
MEFHIKGN_01254	3.62e-213	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
MEFHIKGN_01255	4.23e-246	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MEFHIKGN_01256	1.02e-189	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MEFHIKGN_01257	1.14e-160	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
MEFHIKGN_01259	9.28e-170	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MEFHIKGN_01260	6.39e-124	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MEFHIKGN_01261	1.15e-237	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
MEFHIKGN_01262	1.45e-283	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MEFHIKGN_01263	2.97e-210	yraN	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_01264	5.95e-263	yraM	-	-	S	-	-	-	PrpF protein
MEFHIKGN_01266	5.73e-202	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MEFHIKGN_01267	6.15e-57	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEFHIKGN_01268	4.9e-200	-	-	-	S	-	-	-	Alpha beta hydrolase
MEFHIKGN_01269	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
MEFHIKGN_01270	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
MEFHIKGN_01271	6.62e-87	-	-	-	E	-	-	-	Glyoxalase-like domain
MEFHIKGN_01272	4.19e-50	yraG	-	-	-	ko:K06440	-	ko00000	-
MEFHIKGN_01273	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
MEFHIKGN_01274	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MEFHIKGN_01275	1.05e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
MEFHIKGN_01276	5.95e-65	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
MEFHIKGN_01277	3.17e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MEFHIKGN_01278	3.03e-40	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
MEFHIKGN_01279	8.68e-256	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
MEFHIKGN_01280	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MEFHIKGN_01281	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MEFHIKGN_01282	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MEFHIKGN_01283	6.11e-168	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MEFHIKGN_01284	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
MEFHIKGN_01285	2.66e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MEFHIKGN_01286	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
MEFHIKGN_01287	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MEFHIKGN_01288	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
MEFHIKGN_01289	8.04e-192	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
MEFHIKGN_01290	8.2e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MEFHIKGN_01291	7.4e-193	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
MEFHIKGN_01292	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
MEFHIKGN_01293	5.19e-60	yrhK	-	-	S	-	-	-	YrhK-like protein
MEFHIKGN_01294	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MEFHIKGN_01295	9.22e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
MEFHIKGN_01296	1.5e-124	yrhH	-	-	Q	-	-	-	methyltransferase
MEFHIKGN_01297	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
MEFHIKGN_01299	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
MEFHIKGN_01301	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MEFHIKGN_01302	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
MEFHIKGN_01303	4.97e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MEFHIKGN_01304	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
MEFHIKGN_01305	2.86e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MEFHIKGN_01306	4.07e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
MEFHIKGN_01307	1.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MEFHIKGN_01308	3.44e-153	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
MEFHIKGN_01309	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
MEFHIKGN_01310	1.42e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
MEFHIKGN_01311	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
MEFHIKGN_01312	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEFHIKGN_01313	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MEFHIKGN_01314	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
MEFHIKGN_01315	7.67e-223	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
MEFHIKGN_01316	1.4e-154	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
MEFHIKGN_01317	1.24e-240	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MEFHIKGN_01318	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MEFHIKGN_01319	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MEFHIKGN_01320	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MEFHIKGN_01321	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MEFHIKGN_01322	3.07e-242	yrrI	-	-	S	-	-	-	AI-2E family transporter
MEFHIKGN_01323	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MEFHIKGN_01324	1.01e-184	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MEFHIKGN_01325	6.53e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MEFHIKGN_01326	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MEFHIKGN_01327	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
MEFHIKGN_01328	8.4e-42	yrzR	-	-	-	-	-	-	-
MEFHIKGN_01329	1.23e-108	yrrD	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_01330	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MEFHIKGN_01331	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
MEFHIKGN_01332	5.64e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MEFHIKGN_01333	1.87e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MEFHIKGN_01334	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_01335	8.5e-304	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MEFHIKGN_01336	3.96e-177	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MEFHIKGN_01337	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MEFHIKGN_01338	5.19e-311	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MEFHIKGN_01340	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
MEFHIKGN_01341	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MEFHIKGN_01342	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEFHIKGN_01343	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MEFHIKGN_01344	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MEFHIKGN_01345	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MEFHIKGN_01346	3.77e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MEFHIKGN_01347	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MEFHIKGN_01348	5.53e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
MEFHIKGN_01349	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MEFHIKGN_01350	1.23e-144	yrbG	-	-	S	-	-	-	membrane
MEFHIKGN_01351	1.07e-98	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
MEFHIKGN_01352	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
MEFHIKGN_01353	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MEFHIKGN_01354	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MEFHIKGN_01355	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
MEFHIKGN_01356	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MEFHIKGN_01357	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEFHIKGN_01358	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
MEFHIKGN_01359	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
MEFHIKGN_01360	1.67e-247	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
MEFHIKGN_01361	3.17e-150	yrzF	-	-	T	-	-	-	serine threonine protein kinase
MEFHIKGN_01363	1.47e-66	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
MEFHIKGN_01364	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
MEFHIKGN_01365	2.37e-162	yebC	-	-	K	-	-	-	transcriptional regulatory protein
MEFHIKGN_01366	1.47e-69	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MEFHIKGN_01367	4.02e-216	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
MEFHIKGN_01368	7.94e-273	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MEFHIKGN_01369	4.34e-203	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
MEFHIKGN_01370	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MEFHIKGN_01371	6.49e-288	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MEFHIKGN_01372	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
MEFHIKGN_01373	2.89e-208	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MEFHIKGN_01374	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
MEFHIKGN_01375	5.59e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MEFHIKGN_01376	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
MEFHIKGN_01377	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MEFHIKGN_01378	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
MEFHIKGN_01379	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MEFHIKGN_01380	1.52e-207	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
MEFHIKGN_01381	1.5e-186	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MEFHIKGN_01382	6.84e-185	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MEFHIKGN_01383	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MEFHIKGN_01384	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
MEFHIKGN_01385	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MEFHIKGN_01386	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
MEFHIKGN_01387	1.97e-161	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MEFHIKGN_01388	1.73e-132	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
MEFHIKGN_01389	7.4e-212	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
MEFHIKGN_01390	1.28e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MEFHIKGN_01391	6.38e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MEFHIKGN_01392	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MEFHIKGN_01393	1.53e-35	-	-	-	-	-	-	-	-
MEFHIKGN_01394	3.26e-250	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MEFHIKGN_01395	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
MEFHIKGN_01396	2.04e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MEFHIKGN_01397	1.51e-232	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
MEFHIKGN_01398	2.91e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MEFHIKGN_01399	7.63e-221	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MEFHIKGN_01400	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
MEFHIKGN_01401	2.74e-315	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MEFHIKGN_01402	3.35e-116	ysxD	-	-	-	-	-	-	-
MEFHIKGN_01403	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MEFHIKGN_01404	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MEFHIKGN_01405	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
MEFHIKGN_01406	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MEFHIKGN_01407	7.28e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MEFHIKGN_01408	3.19e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
MEFHIKGN_01409	4.4e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEFHIKGN_01410	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEFHIKGN_01411	7.43e-256	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MEFHIKGN_01412	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MEFHIKGN_01413	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MEFHIKGN_01414	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MEFHIKGN_01415	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MEFHIKGN_01417	3.28e-46	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
MEFHIKGN_01418	1.01e-184	ysnF	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_01420	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MEFHIKGN_01421	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MEFHIKGN_01422	3.53e-171	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MEFHIKGN_01423	1.62e-255	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
MEFHIKGN_01424	4.49e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MEFHIKGN_01425	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MEFHIKGN_01426	2.64e-206	-	-	-	L	-	-	-	Recombinase
MEFHIKGN_01427	4.67e-62	-	-	-	S	-	-	-	YolD-like protein
MEFHIKGN_01430	1.97e-138	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MEFHIKGN_01431	1.58e-41	xhlB	-	-	S	-	-	-	SPP1 phage holin
MEFHIKGN_01432	1.95e-37	xhlA	-	-	S	-	-	-	Haemolysin XhlA
MEFHIKGN_01433	2.89e-17	xkdX	-	-	-	-	-	-	-
MEFHIKGN_01435	2.57e-50	-	-	-	-	-	-	-	-
MEFHIKGN_01436	4.28e-79	-	-	-	-	-	-	-	-
MEFHIKGN_01437	1.21e-133	-	-	-	S	-	-	-	homolog of phage Mu protein gp47
MEFHIKGN_01438	2.25e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MEFHIKGN_01440	1.83e-111	-	-	-	-	-	-	-	-
MEFHIKGN_01441	1.86e-40	-	-	-	-	-	-	-	-
MEFHIKGN_01442	6.22e-47	-	-	-	M	-	-	-	LysM domain
MEFHIKGN_01443	1.28e-162	-	-	-	N	-	-	-	phage tail tape measure protein
MEFHIKGN_01444	3.04e-21	-	-	-	-	-	-	-	-
MEFHIKGN_01445	8.46e-46	-	-	-	-	-	-	-	-
MEFHIKGN_01446	7.99e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
MEFHIKGN_01447	1.46e-40	-	-	-	-	-	-	-	-
MEFHIKGN_01449	2.44e-61	-	-	-	-	-	-	-	-
MEFHIKGN_01451	4.36e-38	-	-	-	S	-	-	-	Phage Mu protein F like protein
MEFHIKGN_01453	2.04e-140	-	-	-	S	-	-	-	Phage capsid family
MEFHIKGN_01454	8.65e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
MEFHIKGN_01455	2.31e-197	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MEFHIKGN_01456	1.33e-235	-	-	-	S	-	-	-	Terminase-like family
MEFHIKGN_01457	4.78e-111	yqaS	-	-	L	-	-	-	DNA packaging
MEFHIKGN_01460	5.2e-19	-	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_01462	2.62e-91	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MEFHIKGN_01466	8.96e-98	-	-	-	-	-	-	-	-
MEFHIKGN_01468	6.2e-35	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
MEFHIKGN_01470	1.57e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
MEFHIKGN_01473	6.12e-152	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
MEFHIKGN_01474	1.37e-45	yqaL	-	-	L	-	-	-	DnaD domain protein
MEFHIKGN_01475	3.08e-149	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
MEFHIKGN_01476	1.55e-192	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
MEFHIKGN_01481	2.69e-88	-	-	-	-	-	-	-	-
MEFHIKGN_01482	3.68e-56	-	-	-	S	-	-	-	DNA binding
MEFHIKGN_01484	1.49e-20	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MEFHIKGN_01485	1.79e-30	-	-	-	K	ko:K07467	-	ko00000	sequence-specific DNA binding
MEFHIKGN_01487	2.71e-20	-	-	-	-	-	-	-	-
MEFHIKGN_01488	3.35e-63	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MEFHIKGN_01489	6.14e-25	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_01490	2.65e-102	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
MEFHIKGN_01491	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MEFHIKGN_01492	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MEFHIKGN_01493	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
MEFHIKGN_01494	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MEFHIKGN_01495	4.83e-276	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MEFHIKGN_01496	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEFHIKGN_01497	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MEFHIKGN_01498	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
MEFHIKGN_01500	7.11e-227	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
MEFHIKGN_01501	2.58e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
MEFHIKGN_01502	2.2e-176	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
MEFHIKGN_01503	3.46e-130	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_01504	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MEFHIKGN_01505	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
MEFHIKGN_01506	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MEFHIKGN_01507	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
MEFHIKGN_01508	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
MEFHIKGN_01509	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MEFHIKGN_01510	2.96e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEFHIKGN_01511	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEFHIKGN_01512	7.36e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MEFHIKGN_01513	7.68e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEFHIKGN_01514	4.37e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
MEFHIKGN_01515	3.88e-264	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
MEFHIKGN_01516	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
MEFHIKGN_01517	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
MEFHIKGN_01518	5.13e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
MEFHIKGN_01519	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
MEFHIKGN_01520	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
MEFHIKGN_01521	1.05e-190	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
MEFHIKGN_01522	6.77e-219	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MEFHIKGN_01523	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MEFHIKGN_01524	1.92e-284	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MEFHIKGN_01525	1.74e-186	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
MEFHIKGN_01526	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MEFHIKGN_01527	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
MEFHIKGN_01528	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MEFHIKGN_01529	4.21e-243	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MEFHIKGN_01530	4.35e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
MEFHIKGN_01531	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
MEFHIKGN_01532	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
MEFHIKGN_01533	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MEFHIKGN_01534	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MEFHIKGN_01535	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MEFHIKGN_01537	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MEFHIKGN_01538	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MEFHIKGN_01539	2.9e-168	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
MEFHIKGN_01540	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_01541	2.07e-191	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
MEFHIKGN_01542	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEFHIKGN_01543	5.98e-206	ytxC	-	-	S	-	-	-	YtxC-like family
MEFHIKGN_01544	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
MEFHIKGN_01545	1.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MEFHIKGN_01546	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
MEFHIKGN_01547	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MEFHIKGN_01548	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MEFHIKGN_01549	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEFHIKGN_01550	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_01551	5.44e-260	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
MEFHIKGN_01552	4.54e-205	ytbE	-	-	S	-	-	-	reductase
MEFHIKGN_01553	2.82e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MEFHIKGN_01554	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MEFHIKGN_01555	4.05e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MEFHIKGN_01556	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MEFHIKGN_01557	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
MEFHIKGN_01558	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEFHIKGN_01559	1.04e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
MEFHIKGN_01560	2.28e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
MEFHIKGN_01561	1.17e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MEFHIKGN_01562	4.46e-93	ytwI	-	-	S	-	-	-	membrane
MEFHIKGN_01563	2.73e-245	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
MEFHIKGN_01564	2.71e-81	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
MEFHIKGN_01565	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MEFHIKGN_01566	1.62e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MEFHIKGN_01567	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MEFHIKGN_01568	2.17e-208	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MEFHIKGN_01569	2.01e-285	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MEFHIKGN_01570	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MEFHIKGN_01571	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
MEFHIKGN_01572	5.12e-112	ytrI	-	-	-	-	-	-	-
MEFHIKGN_01573	1.15e-39	-	-	-	-	-	-	-	-
MEFHIKGN_01574	1.02e-229	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
MEFHIKGN_01575	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
MEFHIKGN_01576	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
MEFHIKGN_01577	6.14e-204	ytnM	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MEFHIKGN_01578	1.58e-301	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MEFHIKGN_01579	1.69e-166	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
MEFHIKGN_01580	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEFHIKGN_01581	5.26e-63	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
MEFHIKGN_01582	1.52e-237	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEFHIKGN_01583	6.61e-183	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MEFHIKGN_01584	4.76e-155	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEFHIKGN_01585	1.66e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEFHIKGN_01586	4.01e-194	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MEFHIKGN_01587	3.18e-195	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MEFHIKGN_01588	8.39e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MEFHIKGN_01589	4.99e-223	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
MEFHIKGN_01590	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
MEFHIKGN_01591	1.98e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEFHIKGN_01593	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MEFHIKGN_01594	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MEFHIKGN_01595	8.14e-115	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MEFHIKGN_01596	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEFHIKGN_01597	3.78e-224	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
MEFHIKGN_01598	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MEFHIKGN_01599	2.24e-96	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
MEFHIKGN_01600	5.03e-150	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
MEFHIKGN_01601	7.05e-113	yteJ	-	-	S	-	-	-	RDD family
MEFHIKGN_01602	2.49e-232	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
MEFHIKGN_01603	2.92e-190	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEFHIKGN_01604	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
MEFHIKGN_01605	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MEFHIKGN_01606	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
MEFHIKGN_01607	6.26e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MEFHIKGN_01608	5.3e-264	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MEFHIKGN_01609	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MEFHIKGN_01610	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MEFHIKGN_01611	1.07e-197	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MEFHIKGN_01612	2.94e-142	yttP	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_01613	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MEFHIKGN_01614	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
MEFHIKGN_01615	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MEFHIKGN_01617	4.36e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEFHIKGN_01618	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MEFHIKGN_01619	2.84e-155	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MEFHIKGN_01620	6.16e-152	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
MEFHIKGN_01621	2.65e-292	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
MEFHIKGN_01622	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MEFHIKGN_01623	3.96e-186	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MEFHIKGN_01624	1.7e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MEFHIKGN_01625	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MEFHIKGN_01626	6.39e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
MEFHIKGN_01627	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
MEFHIKGN_01628	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MEFHIKGN_01629	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MEFHIKGN_01630	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MEFHIKGN_01631	1.78e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEFHIKGN_01632	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
MEFHIKGN_01633	9.1e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
MEFHIKGN_01634	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
MEFHIKGN_01635	9.11e-262	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
MEFHIKGN_01636	1.17e-67	ytzB	-	-	S	-	-	-	small secreted protein
MEFHIKGN_01637	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MEFHIKGN_01638	3.07e-193	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MEFHIKGN_01639	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MEFHIKGN_01640	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
MEFHIKGN_01641	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
MEFHIKGN_01642	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MEFHIKGN_01643	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MEFHIKGN_01644	4.92e-212	ytlQ	-	-	-	-	-	-	-
MEFHIKGN_01645	7.71e-133	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MEFHIKGN_01646	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MEFHIKGN_01647	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
MEFHIKGN_01648	7.02e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MEFHIKGN_01649	3.15e-258	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
MEFHIKGN_01650	3.98e-168	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MEFHIKGN_01651	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
MEFHIKGN_01652	1.23e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MEFHIKGN_01653	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MEFHIKGN_01654	1.41e-293	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
MEFHIKGN_01655	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
MEFHIKGN_01656	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
MEFHIKGN_01657	2.3e-151	yteU	-	-	S	-	-	-	Integral membrane protein
MEFHIKGN_01658	1.07e-315	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MEFHIKGN_01659	5.81e-95	yteS	-	-	G	-	-	-	transport
MEFHIKGN_01660	1.32e-275	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MEFHIKGN_01661	5.35e-220	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
MEFHIKGN_01662	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_01663	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MEFHIKGN_01664	1.02e-191	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MEFHIKGN_01665	1.28e-177	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
MEFHIKGN_01666	2.95e-284	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MEFHIKGN_01667	2.64e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MEFHIKGN_01668	8.91e-157	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MEFHIKGN_01669	1.74e-273	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MEFHIKGN_01670	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MEFHIKGN_01671	9.13e-179	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MEFHIKGN_01672	2.66e-218	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
MEFHIKGN_01673	3.75e-243	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_01674	4.46e-313	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MEFHIKGN_01675	4.75e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MEFHIKGN_01676	7.65e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MEFHIKGN_01677	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MEFHIKGN_01678	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
MEFHIKGN_01679	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MEFHIKGN_01680	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
MEFHIKGN_01681	1.1e-182	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MEFHIKGN_01682	1.21e-268	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
MEFHIKGN_01683	4.46e-56	yttA	-	-	S	-	-	-	Pfam Transposase IS66
MEFHIKGN_01684	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
MEFHIKGN_01685	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_01686	6.44e-239	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
MEFHIKGN_01687	7.76e-168	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEFHIKGN_01688	9.81e-297	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MEFHIKGN_01689	1.02e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_01690	9.19e-191	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
MEFHIKGN_01691	6.58e-197	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MEFHIKGN_01692	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_01693	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
MEFHIKGN_01695	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
MEFHIKGN_01696	2.35e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
MEFHIKGN_01697	1.59e-135	ytqB	-	-	J	-	-	-	Putative rRNA methylase
MEFHIKGN_01698	1.61e-274	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
MEFHIKGN_01699	2.33e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
MEFHIKGN_01700	5.88e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MEFHIKGN_01701	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MEFHIKGN_01702	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MEFHIKGN_01703	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MEFHIKGN_01704	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MEFHIKGN_01705	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
MEFHIKGN_01706	1.06e-187	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MEFHIKGN_01707	9.28e-241	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MEFHIKGN_01708	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MEFHIKGN_01709	1.09e-182	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MEFHIKGN_01710	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MEFHIKGN_01711	1.59e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
MEFHIKGN_01712	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MEFHIKGN_01714	6.79e-95	ytkA	-	-	S	-	-	-	YtkA-like
MEFHIKGN_01715	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MEFHIKGN_01716	8.96e-134	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MEFHIKGN_01717	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MEFHIKGN_01718	7.51e-316	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MEFHIKGN_01719	2.83e-239	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MEFHIKGN_01720	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
MEFHIKGN_01721	9.65e-194	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MEFHIKGN_01722	3.03e-295	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MEFHIKGN_01723	6.86e-176	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MEFHIKGN_01724	2.65e-217	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MEFHIKGN_01725	7.07e-273	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MEFHIKGN_01726	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MEFHIKGN_01727	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MEFHIKGN_01728	1.34e-194	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MEFHIKGN_01729	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MEFHIKGN_01730	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MEFHIKGN_01731	8.68e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MEFHIKGN_01732	1.7e-196	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
MEFHIKGN_01733	2.03e-310	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MEFHIKGN_01734	2.59e-229	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
MEFHIKGN_01735	3.4e-296	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
MEFHIKGN_01737	1.7e-263	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
MEFHIKGN_01738	1.75e-276	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
MEFHIKGN_01739	1.83e-260	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
MEFHIKGN_01740	1.3e-53	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
MEFHIKGN_01741	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MEFHIKGN_01742	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
MEFHIKGN_01743	6.43e-239	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
MEFHIKGN_01744	6.97e-264	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MEFHIKGN_01745	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MEFHIKGN_01761	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
MEFHIKGN_01762	1.2e-122	-	-	-	M	-	-	-	FR47-like protein
MEFHIKGN_01763	9.14e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
MEFHIKGN_01764	4.82e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
MEFHIKGN_01765	1.95e-109	yuaE	-	-	S	-	-	-	DinB superfamily
MEFHIKGN_01766	3.5e-138	yuaD	-	-	-	-	-	-	-
MEFHIKGN_01767	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MEFHIKGN_01768	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MEFHIKGN_01769	2.39e-121	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
MEFHIKGN_01770	8.28e-118	yuaB	-	-	-	-	-	-	-
MEFHIKGN_01771	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MEFHIKGN_01772	1.07e-300	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
MEFHIKGN_01773	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
MEFHIKGN_01774	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEFHIKGN_01775	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
MEFHIKGN_01776	3.95e-113	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
MEFHIKGN_01778	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MEFHIKGN_01779	1.73e-252	yubA	-	-	S	-	-	-	transporter activity
MEFHIKGN_01780	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MEFHIKGN_01781	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
MEFHIKGN_01782	8.22e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
MEFHIKGN_01783	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MEFHIKGN_01784	2.36e-171	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MEFHIKGN_01785	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
MEFHIKGN_01786	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MEFHIKGN_01787	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MEFHIKGN_01788	5.64e-296	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MEFHIKGN_01789	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MEFHIKGN_01790	6.15e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MEFHIKGN_01791	1.44e-47	-	-	-	-	-	-	-	-
MEFHIKGN_01792	4.25e-94	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
MEFHIKGN_01793	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MEFHIKGN_01794	1.03e-299	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MEFHIKGN_01795	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
MEFHIKGN_01796	1.58e-50	-	-	-	-	-	-	-	-
MEFHIKGN_01797	5.01e-69	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
MEFHIKGN_01798	1.02e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
MEFHIKGN_01799	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
MEFHIKGN_01801	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MEFHIKGN_01802	6.49e-290	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
MEFHIKGN_01803	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
MEFHIKGN_01804	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
MEFHIKGN_01805	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MEFHIKGN_01806	5.2e-253	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
MEFHIKGN_01807	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_01808	9.89e-201	yugF	-	-	I	-	-	-	Hydrolase
MEFHIKGN_01809	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
MEFHIKGN_01810	3.19e-284	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MEFHIKGN_01811	1.76e-295	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_01812	6.12e-92	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
MEFHIKGN_01813	8.49e-150	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
MEFHIKGN_01815	8.9e-242	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
MEFHIKGN_01816	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
MEFHIKGN_01817	3.31e-98	yuxK	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_01818	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
MEFHIKGN_01819	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MEFHIKGN_01820	3.26e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MEFHIKGN_01821	1.28e-253	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
MEFHIKGN_01822	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_01823	9.08e-237	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MEFHIKGN_01824	4.03e-214	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MEFHIKGN_01825	9.73e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
MEFHIKGN_01826	1.42e-21	-	-	-	-	-	-	-	-
MEFHIKGN_01827	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MEFHIKGN_01828	8.95e-90	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MEFHIKGN_01829	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MEFHIKGN_01830	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MEFHIKGN_01831	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MEFHIKGN_01832	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MEFHIKGN_01833	5.97e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
MEFHIKGN_01834	1.11e-82	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
MEFHIKGN_01835	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEFHIKGN_01836	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_01838	3.33e-168	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
MEFHIKGN_01839	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
MEFHIKGN_01841	8.73e-09	yuzC	-	-	-	-	-	-	-
MEFHIKGN_01842	6.88e-297	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
MEFHIKGN_01843	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEFHIKGN_01844	3.27e-134	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
MEFHIKGN_01845	2.19e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MEFHIKGN_01846	1.34e-51	yueH	-	-	S	-	-	-	YueH-like protein
MEFHIKGN_01847	1.23e-43	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
MEFHIKGN_01848	4.72e-245	yueF	-	-	S	-	-	-	transporter activity
MEFHIKGN_01849	6.1e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
MEFHIKGN_01850	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
MEFHIKGN_01851	7.78e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MEFHIKGN_01852	6.1e-171	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEFHIKGN_01853	1.78e-96	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
MEFHIKGN_01854	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
MEFHIKGN_01855	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MEFHIKGN_01856	2.21e-271	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
MEFHIKGN_01857	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
MEFHIKGN_01858	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
MEFHIKGN_01859	1.03e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
MEFHIKGN_01860	4.02e-262	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
MEFHIKGN_01861	6.94e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
MEFHIKGN_01862	8.23e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
MEFHIKGN_01863	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEFHIKGN_01864	3.83e-229	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
MEFHIKGN_01865	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
MEFHIKGN_01866	2.99e-290	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MEFHIKGN_01867	1.43e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFHIKGN_01868	1.55e-213	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
MEFHIKGN_01869	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
MEFHIKGN_01870	4.81e-124	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
MEFHIKGN_01871	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
MEFHIKGN_01872	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MEFHIKGN_01873	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
MEFHIKGN_01874	1.69e-151	yuiC	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_01875	9.78e-47	yuiB	-	-	S	-	-	-	Putative membrane protein
MEFHIKGN_01876	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MEFHIKGN_01877	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
MEFHIKGN_01879	4.51e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEFHIKGN_01880	9.91e-150	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
MEFHIKGN_01881	5.66e-115	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEFHIKGN_01882	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
MEFHIKGN_01883	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MEFHIKGN_01884	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MEFHIKGN_01885	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
MEFHIKGN_01886	4.54e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MEFHIKGN_01887	6.61e-75	yuzD	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_01888	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
MEFHIKGN_01889	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
MEFHIKGN_01890	4.96e-219	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MEFHIKGN_01891	1.05e-250	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MEFHIKGN_01892	1.67e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MEFHIKGN_01893	1.55e-253	yutH	-	-	S	-	-	-	Spore coat protein
MEFHIKGN_01894	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MEFHIKGN_01895	3.69e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MEFHIKGN_01896	1.96e-98	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
MEFHIKGN_01897	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_01898	1.29e-142	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MEFHIKGN_01899	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MEFHIKGN_01900	7.63e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
MEFHIKGN_01901	4.25e-172	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
MEFHIKGN_01902	3.41e-65	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
MEFHIKGN_01903	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MEFHIKGN_01904	1.86e-180	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MEFHIKGN_01905	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
MEFHIKGN_01906	4.35e-79	yunG	-	-	-	-	-	-	-
MEFHIKGN_01907	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MEFHIKGN_01908	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
MEFHIKGN_01909	4.46e-295	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
MEFHIKGN_01910	1.84e-282	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
MEFHIKGN_01911	4.38e-104	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MEFHIKGN_01912	4.74e-231	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MEFHIKGN_01913	5.98e-72	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MEFHIKGN_01914	0.000154	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MEFHIKGN_01915	2.95e-123	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MEFHIKGN_01916	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MEFHIKGN_01917	4.85e-194	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MEFHIKGN_01918	2.62e-144	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
MEFHIKGN_01919	4.21e-242	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MEFHIKGN_01921	8.51e-306	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MEFHIKGN_01922	4.9e-303	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MEFHIKGN_01923	6.53e-218	bsn	-	-	L	-	-	-	Ribonuclease
MEFHIKGN_01924	2.95e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MEFHIKGN_01925	7.46e-176	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MEFHIKGN_01926	9.57e-209	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
MEFHIKGN_01927	1.94e-216	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MEFHIKGN_01928	3.54e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEFHIKGN_01929	2.46e-308	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MEFHIKGN_01930	2.24e-236	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MEFHIKGN_01931	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
MEFHIKGN_01932	1.42e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
MEFHIKGN_01934	3.35e-56	-	-	-	-	-	-	-	-
MEFHIKGN_01935	2.14e-87	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEFHIKGN_01936	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
MEFHIKGN_01937	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
MEFHIKGN_01938	2.81e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MEFHIKGN_01939	7.43e-313	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
MEFHIKGN_01940	4.46e-182	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MEFHIKGN_01941	1.56e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MEFHIKGN_01942	1.01e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
MEFHIKGN_01943	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MEFHIKGN_01944	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEFHIKGN_01945	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
MEFHIKGN_01946	2e-73	yusE	-	-	CO	-	-	-	Thioredoxin
MEFHIKGN_01947	2.18e-96	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
MEFHIKGN_01948	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
MEFHIKGN_01949	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MEFHIKGN_01950	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MEFHIKGN_01951	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MEFHIKGN_01952	2.22e-277	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
MEFHIKGN_01953	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
MEFHIKGN_01954	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
MEFHIKGN_01955	3.46e-211	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MEFHIKGN_01956	2.23e-54	-	-	-	-	-	-	-	-
MEFHIKGN_01957	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
MEFHIKGN_01958	4.47e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
MEFHIKGN_01959	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
MEFHIKGN_01960	1.7e-84	yusQ	-	-	S	-	-	-	Tautomerase enzyme
MEFHIKGN_01961	4.97e-138	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFHIKGN_01962	4.87e-203	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
MEFHIKGN_01963	3.66e-64	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
MEFHIKGN_01964	1.06e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MEFHIKGN_01965	3.48e-88	-	-	-	S	-	-	-	YusW-like protein
MEFHIKGN_01966	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
MEFHIKGN_01967	1.91e-197	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFHIKGN_01968	1.07e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
MEFHIKGN_01969	9.63e-306	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MEFHIKGN_01970	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEFHIKGN_01971	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_01972	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_01973	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MEFHIKGN_01974	4.48e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
MEFHIKGN_01975	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MEFHIKGN_01976	2.9e-253	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MEFHIKGN_01977	3.48e-249	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MEFHIKGN_01978	9.39e-141	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEFHIKGN_01979	4.06e-246	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_01980	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
MEFHIKGN_01981	6.57e-178	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MEFHIKGN_01982	4.22e-144	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MEFHIKGN_01983	1.51e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
MEFHIKGN_01984	1.13e-288	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_01985	8.21e-133	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
MEFHIKGN_01986	0.0	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MEFHIKGN_01987	3.29e-237	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEFHIKGN_01988	5.15e-219	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MEFHIKGN_01989	5.21e-182	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFHIKGN_01990	1.32e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
MEFHIKGN_01991	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
MEFHIKGN_01992	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEFHIKGN_01993	5.07e-32	-	-	-	-	-	-	-	-
MEFHIKGN_01994	5.77e-127	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
MEFHIKGN_01995	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
MEFHIKGN_01996	1.21e-289	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MEFHIKGN_01997	2.84e-85	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
MEFHIKGN_01998	1.94e-271	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MEFHIKGN_01999	1.33e-158	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_02000	2.69e-226	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
MEFHIKGN_02001	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MEFHIKGN_02002	9.64e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEFHIKGN_02003	1.21e-236	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEFHIKGN_02004	1.33e-226	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MEFHIKGN_02006	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MEFHIKGN_02007	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
MEFHIKGN_02008	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MEFHIKGN_02009	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
MEFHIKGN_02010	2.54e-214	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
MEFHIKGN_02011	1.09e-177	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
MEFHIKGN_02012	1.01e-152	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
MEFHIKGN_02013	3.07e-201	yvgN	-	-	S	-	-	-	reductase
MEFHIKGN_02014	9.32e-112	yvgO	-	-	-	-	-	-	-
MEFHIKGN_02015	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
MEFHIKGN_02016	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MEFHIKGN_02017	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MEFHIKGN_02018	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MEFHIKGN_02020	3.32e-139	yvgT	-	-	S	-	-	-	membrane
MEFHIKGN_02021	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
MEFHIKGN_02022	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
MEFHIKGN_02023	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MEFHIKGN_02024	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MEFHIKGN_02025	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
MEFHIKGN_02026	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
MEFHIKGN_02027	3.44e-248	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MEFHIKGN_02028	3.59e-154	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MEFHIKGN_02029	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
MEFHIKGN_02030	8.22e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
MEFHIKGN_02031	3.52e-71	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
MEFHIKGN_02032	1.36e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MEFHIKGN_02033	6.56e-181	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFHIKGN_02035	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MEFHIKGN_02036	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MEFHIKGN_02037	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
MEFHIKGN_02038	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
MEFHIKGN_02039	1.92e-194	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
MEFHIKGN_02040	3.44e-48	yvzC	-	-	K	-	-	-	transcriptional
MEFHIKGN_02041	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
MEFHIKGN_02042	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MEFHIKGN_02043	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
MEFHIKGN_02044	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MEFHIKGN_02045	9.2e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MEFHIKGN_02046	6.8e-220	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MEFHIKGN_02047	1.55e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MEFHIKGN_02048	3.64e-271	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MEFHIKGN_02049	1.15e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MEFHIKGN_02050	2.75e-11	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
MEFHIKGN_02051	1.13e-222	-	-	-	-	-	-	-	-
MEFHIKGN_02053	1.13e-130	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MEFHIKGN_02054	9.63e-60	sdpR	-	-	K	-	-	-	transcriptional
MEFHIKGN_02055	1.03e-146	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MEFHIKGN_02056	1.49e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MEFHIKGN_02057	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MEFHIKGN_02058	5.58e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MEFHIKGN_02059	1.74e-130	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MEFHIKGN_02060	9.68e-136	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
MEFHIKGN_02061	1.03e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
MEFHIKGN_02062	7.97e-157	yvbI	-	-	M	-	-	-	Membrane
MEFHIKGN_02063	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MEFHIKGN_02064	9.77e-106	yvbK	-	-	K	-	-	-	acetyltransferase
MEFHIKGN_02065	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEFHIKGN_02066	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
MEFHIKGN_02067	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEFHIKGN_02068	1.62e-276	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MEFHIKGN_02069	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEFHIKGN_02070	1.63e-235	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MEFHIKGN_02071	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MEFHIKGN_02072	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
MEFHIKGN_02073	1.04e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEFHIKGN_02074	6.96e-206	yvbU	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02075	3.93e-198	yvbV	-	-	EG	-	-	-	EamA-like transporter family
MEFHIKGN_02076	1.43e-306	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MEFHIKGN_02077	4.44e-251	-	-	-	S	-	-	-	Glycosyl hydrolase
MEFHIKGN_02078	1.45e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MEFHIKGN_02079	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MEFHIKGN_02080	2.14e-173	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MEFHIKGN_02081	2.52e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEFHIKGN_02082	2.98e-249	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_02083	4.81e-169	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MEFHIKGN_02084	5.95e-209	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MEFHIKGN_02085	7.25e-201	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
MEFHIKGN_02086	8.02e-261	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
MEFHIKGN_02087	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
MEFHIKGN_02088	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
MEFHIKGN_02089	3.82e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MEFHIKGN_02090	1.3e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MEFHIKGN_02091	2.05e-295	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MEFHIKGN_02092	6.42e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_02093	1.18e-146	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
MEFHIKGN_02094	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MEFHIKGN_02095	9.59e-304	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MEFHIKGN_02096	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
MEFHIKGN_02097	1.03e-238	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
MEFHIKGN_02098	5.25e-279	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MEFHIKGN_02099	1.15e-80	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MEFHIKGN_02100	3.19e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MEFHIKGN_02101	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MEFHIKGN_02102	1.86e-243	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MEFHIKGN_02103	3.16e-258	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
MEFHIKGN_02104	1.66e-246	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MEFHIKGN_02105	2.95e-263	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
MEFHIKGN_02106	2.06e-277	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MEFHIKGN_02107	1.25e-201	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
MEFHIKGN_02108	6.66e-283	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
MEFHIKGN_02109	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MEFHIKGN_02110	3.77e-148	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MEFHIKGN_02111	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MEFHIKGN_02112	1.45e-97	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
MEFHIKGN_02113	3.33e-84	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MEFHIKGN_02114	1.57e-243	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MEFHIKGN_02116	3.13e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MEFHIKGN_02117	2.59e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
MEFHIKGN_02118	1.76e-162	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MEFHIKGN_02119	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
MEFHIKGN_02120	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
MEFHIKGN_02121	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MEFHIKGN_02122	0.0	ybeC	-	-	E	-	-	-	amino acid
MEFHIKGN_02123	1.17e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02124	3.65e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MEFHIKGN_02125	1.03e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
MEFHIKGN_02126	5.53e-122	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
MEFHIKGN_02127	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
MEFHIKGN_02128	2.71e-233	-	-	-	S	-	-	-	Patatin-like phospholipase
MEFHIKGN_02130	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEFHIKGN_02131	6.78e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MEFHIKGN_02132	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MEFHIKGN_02133	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
MEFHIKGN_02134	3.96e-197	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MEFHIKGN_02135	6.84e-190	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MEFHIKGN_02136	5e-310	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MEFHIKGN_02137	2.42e-301	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MEFHIKGN_02138	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
MEFHIKGN_02139	1.27e-220	yvdE	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02140	5.37e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MEFHIKGN_02141	3.2e-70	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MEFHIKGN_02142	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MEFHIKGN_02143	4.36e-136	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MEFHIKGN_02144	1.15e-234	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEFHIKGN_02145	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MEFHIKGN_02146	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_02147	2.78e-251	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MEFHIKGN_02148	4.67e-172	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEFHIKGN_02149	1.32e-43	-	-	-	-	-	-	-	-
MEFHIKGN_02150	2.3e-182	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
MEFHIKGN_02151	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
MEFHIKGN_02152	3.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MEFHIKGN_02153	6.72e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MEFHIKGN_02154	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MEFHIKGN_02155	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MEFHIKGN_02156	1.18e-225	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MEFHIKGN_02157	1.08e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
MEFHIKGN_02158	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
MEFHIKGN_02159	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MEFHIKGN_02161	0.0	-	-	-	-	-	-	-	-
MEFHIKGN_02162	6.58e-95	-	-	-	-	-	-	-	-
MEFHIKGN_02163	2.5e-90	-	-	-	-	-	-	-	-
MEFHIKGN_02164	2.51e-144	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
MEFHIKGN_02165	2.79e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MEFHIKGN_02166	3.95e-168	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MEFHIKGN_02167	1.2e-148	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MEFHIKGN_02168	3.35e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
MEFHIKGN_02169	3e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MEFHIKGN_02170	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MEFHIKGN_02171	2.82e-280	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MEFHIKGN_02172	2.49e-178	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
MEFHIKGN_02173	1.1e-153	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
MEFHIKGN_02174	5.94e-118	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MEFHIKGN_02175	1.06e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MEFHIKGN_02176	6.16e-210	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
MEFHIKGN_02177	3.18e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MEFHIKGN_02178	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MEFHIKGN_02179	9.39e-277	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MEFHIKGN_02180	3.66e-167	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MEFHIKGN_02181	1.75e-170	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
MEFHIKGN_02182	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
MEFHIKGN_02183	9.4e-110	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MEFHIKGN_02184	1.88e-292	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MEFHIKGN_02185	2.49e-177	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MEFHIKGN_02186	8.46e-112	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MEFHIKGN_02187	6.05e-272	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
MEFHIKGN_02188	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
MEFHIKGN_02189	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MEFHIKGN_02190	5.8e-221	yvlB	-	-	S	-	-	-	Putative adhesin
MEFHIKGN_02191	8.09e-65	yvlA	-	-	-	-	-	-	-
MEFHIKGN_02192	2.25e-45	yvkN	-	-	-	-	-	-	-
MEFHIKGN_02193	2.02e-101	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MEFHIKGN_02194	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MEFHIKGN_02195	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MEFHIKGN_02196	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_02197	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
MEFHIKGN_02198	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02199	5.47e-298	yvkA	-	-	P	-	-	-	-transporter
MEFHIKGN_02200	3.17e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MEFHIKGN_02201	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
MEFHIKGN_02202	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MEFHIKGN_02203	1.1e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MEFHIKGN_02204	1.5e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
MEFHIKGN_02205	3.23e-75	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MEFHIKGN_02206	6.5e-185	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MEFHIKGN_02207	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MEFHIKGN_02208	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEFHIKGN_02209	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MEFHIKGN_02210	9.14e-88	-	-	-	-	-	-	-	-
MEFHIKGN_02211	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
MEFHIKGN_02212	5.15e-91	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
MEFHIKGN_02213	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MEFHIKGN_02214	1.1e-76	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
MEFHIKGN_02215	8.01e-202	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MEFHIKGN_02216	2.58e-41	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MEFHIKGN_02217	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MEFHIKGN_02218	4.19e-93	yviE	-	-	-	-	-	-	-
MEFHIKGN_02219	1.97e-199	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
MEFHIKGN_02220	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
MEFHIKGN_02221	3.5e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
MEFHIKGN_02222	1.06e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
MEFHIKGN_02223	1.83e-96	yvyF	-	-	S	-	-	-	flagellar protein
MEFHIKGN_02224	9.99e-166	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
MEFHIKGN_02225	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
MEFHIKGN_02226	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MEFHIKGN_02227	2.15e-199	degV	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_02228	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEFHIKGN_02229	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MEFHIKGN_02230	2.41e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
MEFHIKGN_02231	3.99e-225	yvhJ	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02232	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MEFHIKGN_02233	3.3e-303	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
MEFHIKGN_02234	8.42e-187	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MEFHIKGN_02235	6.04e-149	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
MEFHIKGN_02236	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
MEFHIKGN_02237	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MEFHIKGN_02238	4.66e-278	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
MEFHIKGN_02239	2.58e-316	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MEFHIKGN_02240	1.49e-143	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MEFHIKGN_02241	4.98e-108	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MEFHIKGN_02242	2.25e-265	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MEFHIKGN_02243	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
MEFHIKGN_02244	4.58e-16	-	-	-	-	-	-	-	-
MEFHIKGN_02245	1.16e-211	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MEFHIKGN_02246	1.56e-276	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MEFHIKGN_02247	1.06e-103	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MEFHIKGN_02248	1.37e-117	-	-	-	M	-	-	-	Glycosyl transferases group 1
MEFHIKGN_02250	3.9e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MEFHIKGN_02251	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MEFHIKGN_02252	4.79e-168	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
MEFHIKGN_02253	0.0	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MEFHIKGN_02254	1.26e-304	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MEFHIKGN_02255	1.2e-170	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MEFHIKGN_02256	1.88e-73	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
MEFHIKGN_02257	6.82e-111	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MEFHIKGN_02258	8.85e-116	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MEFHIKGN_02259	1.7e-133	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MEFHIKGN_02260	5.68e-186	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MEFHIKGN_02261	1.34e-109	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	M	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MEFHIKGN_02262	1.42e-235	tarL	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MEFHIKGN_02263	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEFHIKGN_02264	1.07e-237	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MEFHIKGN_02265	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MEFHIKGN_02266	1.73e-247	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MEFHIKGN_02267	2.52e-263	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MEFHIKGN_02268	8.19e-316	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MEFHIKGN_02269	1.48e-222	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02270	7.24e-205	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MEFHIKGN_02271	1.37e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MEFHIKGN_02272	2.29e-29	ywtC	-	-	-	-	-	-	-
MEFHIKGN_02273	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MEFHIKGN_02274	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
MEFHIKGN_02275	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
MEFHIKGN_02276	2.68e-227	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MEFHIKGN_02277	6.44e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEFHIKGN_02278	5.6e-85	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MEFHIKGN_02279	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MEFHIKGN_02280	3.35e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MEFHIKGN_02281	9.04e-204	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
MEFHIKGN_02282	2.05e-121	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
MEFHIKGN_02283	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
MEFHIKGN_02284	8.76e-126	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
MEFHIKGN_02285	1.84e-187	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MEFHIKGN_02286	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MEFHIKGN_02287	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
MEFHIKGN_02288	3.25e-279	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MEFHIKGN_02289	9.09e-164	ywrJ	-	-	-	-	-	-	-
MEFHIKGN_02290	1.35e-180	cotB	-	-	-	ko:K06325	-	ko00000	-
MEFHIKGN_02291	4.57e-269	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MEFHIKGN_02292	2.17e-16	-	-	-	-	-	-	-	-
MEFHIKGN_02293	1.77e-142	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MEFHIKGN_02294	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
MEFHIKGN_02295	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MEFHIKGN_02296	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MEFHIKGN_02297	4.53e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
MEFHIKGN_02298	6.07e-114	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
MEFHIKGN_02300	2.91e-127	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
MEFHIKGN_02301	4.73e-209	-	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02302	4.92e-154	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MEFHIKGN_02303	1.13e-126	-	-	-	-	-	-	-	-
MEFHIKGN_02305	2.2e-66	-	-	-	-	-	-	-	-
MEFHIKGN_02306	1.29e-97	-	-	-	-	-	-	-	-
MEFHIKGN_02307	1.95e-297	ywqJ	-	-	S	-	-	-	Pre-toxin TG
MEFHIKGN_02308	4.98e-50	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
MEFHIKGN_02310	1.2e-195	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
MEFHIKGN_02311	2.21e-311	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MEFHIKGN_02312	5.87e-179	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
MEFHIKGN_02313	1.76e-153	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MEFHIKGN_02314	3.6e-161	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MEFHIKGN_02315	3.6e-25	-	-	-	-	-	-	-	-
MEFHIKGN_02316	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
MEFHIKGN_02317	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MEFHIKGN_02318	1.24e-200	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MEFHIKGN_02319	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MEFHIKGN_02320	8.53e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MEFHIKGN_02321	3.04e-87	ywpG	-	-	-	-	-	-	-
MEFHIKGN_02322	8.81e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
MEFHIKGN_02323	3.81e-67	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MEFHIKGN_02324	4.34e-189	ywpD	-	-	T	-	-	-	Histidine kinase
MEFHIKGN_02325	1.32e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MEFHIKGN_02326	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEFHIKGN_02327	6.36e-256	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
MEFHIKGN_02328	9.65e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MEFHIKGN_02329	1.19e-170	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MEFHIKGN_02330	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
MEFHIKGN_02331	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
MEFHIKGN_02332	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
MEFHIKGN_02333	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_02334	1.45e-312	ywoF	-	-	P	-	-	-	Right handed beta helix region
MEFHIKGN_02335	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
MEFHIKGN_02336	3.63e-305	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
MEFHIKGN_02337	1.04e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
MEFHIKGN_02338	4.15e-100	-	-	-	-	-	-	-	-
MEFHIKGN_02339	6.5e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
MEFHIKGN_02340	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
MEFHIKGN_02341	6.02e-135	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
MEFHIKGN_02342	2.35e-152	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
MEFHIKGN_02343	2.47e-26	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MEFHIKGN_02344	1.65e-40	-	-	-	L	-	-	-	Restriction endonuclease BamHI
MEFHIKGN_02345	1.85e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MEFHIKGN_02346	5.19e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
MEFHIKGN_02347	1.31e-21	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MEFHIKGN_02348	7.07e-92	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
MEFHIKGN_02349	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEFHIKGN_02350	2.69e-181	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
MEFHIKGN_02351	1.06e-78	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MEFHIKGN_02352	1.29e-148	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MEFHIKGN_02353	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02354	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MEFHIKGN_02355	7.55e-82	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
MEFHIKGN_02356	8.2e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
MEFHIKGN_02358	1.51e-19	csbD	-	-	K	-	-	-	CsbD-like
MEFHIKGN_02359	1.12e-109	ywmF	-	-	S	-	-	-	Peptidase M50
MEFHIKGN_02360	1.25e-128	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MEFHIKGN_02361	2.65e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MEFHIKGN_02362	2.22e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MEFHIKGN_02364	1.02e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MEFHIKGN_02365	1.89e-157	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MEFHIKGN_02366	3.27e-232	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
MEFHIKGN_02367	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEFHIKGN_02368	6.32e-170	ywmB	-	-	S	-	-	-	TATA-box binding
MEFHIKGN_02369	4.54e-45	ywzB	-	-	S	-	-	-	membrane
MEFHIKGN_02370	6.12e-115	ywmA	-	-	-	-	-	-	-
MEFHIKGN_02371	2.44e-75	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MEFHIKGN_02372	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MEFHIKGN_02373	4.46e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MEFHIKGN_02374	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MEFHIKGN_02375	2.89e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEFHIKGN_02376	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MEFHIKGN_02377	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEFHIKGN_02378	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MEFHIKGN_02379	2.23e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
MEFHIKGN_02380	6.42e-147	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MEFHIKGN_02381	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MEFHIKGN_02382	7.13e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MEFHIKGN_02383	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
MEFHIKGN_02384	9.54e-102	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MEFHIKGN_02385	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MEFHIKGN_02386	3.5e-249	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MEFHIKGN_02387	1.79e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
MEFHIKGN_02388	1.14e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
MEFHIKGN_02389	7.97e-73	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MEFHIKGN_02391	3.44e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MEFHIKGN_02392	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MEFHIKGN_02393	1.39e-88	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEFHIKGN_02394	6.01e-117	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MEFHIKGN_02395	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MEFHIKGN_02396	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MEFHIKGN_02397	4.06e-134	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MEFHIKGN_02398	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MEFHIKGN_02399	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MEFHIKGN_02400	3.51e-225	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
MEFHIKGN_02401	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEFHIKGN_02402	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MEFHIKGN_02403	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
MEFHIKGN_02404	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
MEFHIKGN_02405	2.24e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
MEFHIKGN_02406	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MEFHIKGN_02407	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MEFHIKGN_02408	4.95e-268	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
MEFHIKGN_02409	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
MEFHIKGN_02410	8.56e-290	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MEFHIKGN_02411	4.88e-236	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MEFHIKGN_02412	1.32e-57	ywjC	-	-	-	-	-	-	-
MEFHIKGN_02413	1.57e-123	ywjB	-	-	H	-	-	-	RibD C-terminal domain
MEFHIKGN_02414	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MEFHIKGN_02415	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEFHIKGN_02416	2.06e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
MEFHIKGN_02417	1.95e-122	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
MEFHIKGN_02418	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
MEFHIKGN_02419	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MEFHIKGN_02420	8.67e-111	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
MEFHIKGN_02421	1.84e-179	ywiC	-	-	S	-	-	-	YwiC-like protein
MEFHIKGN_02422	3.27e-168	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
MEFHIKGN_02423	1.7e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MEFHIKGN_02424	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MEFHIKGN_02425	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_02426	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
MEFHIKGN_02427	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
MEFHIKGN_02429	1.23e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MEFHIKGN_02430	8.05e-296	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
MEFHIKGN_02431	4.88e-276	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
MEFHIKGN_02432	3.32e-315	-	-	-	L	-	-	-	Peptidase, M16
MEFHIKGN_02434	9.08e-317	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
MEFHIKGN_02435	9.47e-275	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
MEFHIKGN_02436	3.28e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MEFHIKGN_02438	2.17e-37	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
MEFHIKGN_02439	6.02e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MEFHIKGN_02440	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MEFHIKGN_02441	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MEFHIKGN_02442	7.83e-123	ywhD	-	-	S	-	-	-	YwhD family
MEFHIKGN_02443	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
MEFHIKGN_02444	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
MEFHIKGN_02445	1.45e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02446	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEFHIKGN_02448	2.66e-307	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
MEFHIKGN_02449	1.1e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02450	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
MEFHIKGN_02451	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
MEFHIKGN_02452	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
MEFHIKGN_02453	1.88e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
MEFHIKGN_02454	1.57e-204	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
MEFHIKGN_02455	2.15e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MEFHIKGN_02456	4.54e-210	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_02457	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
MEFHIKGN_02458	3.43e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
MEFHIKGN_02459	2.77e-175	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
MEFHIKGN_02460	9e-297	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MEFHIKGN_02461	3.21e-267	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MEFHIKGN_02462	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MEFHIKGN_02463	1.33e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEFHIKGN_02464	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MEFHIKGN_02465	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MEFHIKGN_02466	5.41e-275	ywfA	-	-	EGP	-	-	-	-transporter
MEFHIKGN_02467	1.77e-316	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MEFHIKGN_02468	1.09e-42	rocB	-	-	E	-	-	-	arginine degradation protein
MEFHIKGN_02469	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MEFHIKGN_02470	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MEFHIKGN_02471	8.6e-310	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MEFHIKGN_02472	1.51e-100	-	-	-	-	-	-	-	-
MEFHIKGN_02473	9.16e-114	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
MEFHIKGN_02474	1.41e-205	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MEFHIKGN_02475	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEFHIKGN_02476	2.14e-177	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MEFHIKGN_02477	5.73e-240	spsG	-	-	M	-	-	-	Spore Coat
MEFHIKGN_02478	1.09e-167	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
MEFHIKGN_02479	1.13e-270	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
MEFHIKGN_02480	7e-209	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
MEFHIKGN_02481	6.44e-285	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MEFHIKGN_02482	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
MEFHIKGN_02483	7.76e-185	spsA	-	-	M	-	-	-	Spore Coat
MEFHIKGN_02484	3.62e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MEFHIKGN_02485	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
MEFHIKGN_02486	3.75e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
MEFHIKGN_02487	2.65e-64	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
MEFHIKGN_02488	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MEFHIKGN_02489	9.47e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MEFHIKGN_02490	4.68e-192	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
MEFHIKGN_02492	2.4e-143	ywdD	-	-	-	-	-	-	-
MEFHIKGN_02493	7.92e-76	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
MEFHIKGN_02494	2.21e-187	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MEFHIKGN_02495	6.19e-39	ywdA	-	-	-	-	-	-	-
MEFHIKGN_02496	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MEFHIKGN_02497	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MEFHIKGN_02498	2.79e-178	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
MEFHIKGN_02499	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MEFHIKGN_02501	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MEFHIKGN_02502	3.44e-238	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEFHIKGN_02503	9.4e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
MEFHIKGN_02504	1.26e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MEFHIKGN_02505	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
MEFHIKGN_02506	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MEFHIKGN_02507	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MEFHIKGN_02508	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MEFHIKGN_02509	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MEFHIKGN_02510	5.11e-49	ydaS	-	-	S	-	-	-	membrane
MEFHIKGN_02511	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MEFHIKGN_02512	1.12e-290	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MEFHIKGN_02513	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
MEFHIKGN_02514	3.42e-158	ywcC	-	-	K	-	-	-	transcriptional regulator
MEFHIKGN_02516	4.29e-64	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
MEFHIKGN_02517	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEFHIKGN_02518	1.26e-144	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MEFHIKGN_02519	1.04e-306	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
MEFHIKGN_02520	6.92e-246	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
MEFHIKGN_02521	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
MEFHIKGN_02522	1.74e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MEFHIKGN_02523	1.32e-184	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MEFHIKGN_02524	1.56e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02525	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MEFHIKGN_02526	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
MEFHIKGN_02527	4.31e-277	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
MEFHIKGN_02528	3.13e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
MEFHIKGN_02529	4.67e-279	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
MEFHIKGN_02530	4.01e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
MEFHIKGN_02531	7.07e-309	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFHIKGN_02532	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MEFHIKGN_02533	6.87e-311	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MEFHIKGN_02534	1.06e-194	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MEFHIKGN_02535	4.41e-215	gspA	-	-	M	-	-	-	General stress
MEFHIKGN_02536	8.23e-157	ywaF	-	-	S	-	-	-	Integral membrane protein
MEFHIKGN_02537	1.25e-114	ywaE	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02538	4.11e-293	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEFHIKGN_02539	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
MEFHIKGN_02540	5.37e-116	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MEFHIKGN_02541	5.58e-64	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MEFHIKGN_02542	3.96e-165	-	-	-	EGP	-	-	-	Permeases of the major facilitator superfamily
MEFHIKGN_02543	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
MEFHIKGN_02544	5.1e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MEFHIKGN_02545	1.27e-20	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MEFHIKGN_02546	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEFHIKGN_02547	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
MEFHIKGN_02548	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEFHIKGN_02549	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MEFHIKGN_02550	2.91e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFHIKGN_02551	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MEFHIKGN_02552	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MEFHIKGN_02553	1.58e-50	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MEFHIKGN_02554	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFHIKGN_02555	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
MEFHIKGN_02556	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MEFHIKGN_02557	8.94e-28	yxzF	-	-	-	-	-	-	-
MEFHIKGN_02558	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MEFHIKGN_02559	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MEFHIKGN_02560	3.64e-56	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
MEFHIKGN_02561	4.25e-200	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
MEFHIKGN_02562	3.96e-179	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MEFHIKGN_02563	5.52e-209	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_02564	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
MEFHIKGN_02565	2.92e-42	-	-	-	-	-	-	-	-
MEFHIKGN_02566	4.05e-64	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
MEFHIKGN_02567	1.29e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MEFHIKGN_02568	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MEFHIKGN_02569	9.16e-203	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MEFHIKGN_02570	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
MEFHIKGN_02571	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
MEFHIKGN_02572	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
MEFHIKGN_02573	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MEFHIKGN_02574	3.97e-310	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
MEFHIKGN_02575	0.0	-	-	-	O	-	-	-	Peptidase family M48
MEFHIKGN_02577	7.49e-199	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
MEFHIKGN_02578	1.4e-260	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MEFHIKGN_02579	7.85e-210	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MEFHIKGN_02580	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MEFHIKGN_02581	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEFHIKGN_02582	1.17e-98	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MEFHIKGN_02583	4.98e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MEFHIKGN_02584	7.88e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MEFHIKGN_02585	3.62e-212	-	-	-	K	-	-	-	LysR substrate binding domain
MEFHIKGN_02586	7.69e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
MEFHIKGN_02587	1.37e-258	-	-	-	T	-	-	-	Signal transduction histidine kinase
MEFHIKGN_02588	7.4e-146	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
MEFHIKGN_02589	4.49e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MEFHIKGN_02592	1.43e-111	yxjI	-	-	S	-	-	-	LURP-one-related
MEFHIKGN_02593	1.5e-277	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MEFHIKGN_02594	1.55e-275	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MEFHIKGN_02595	2.77e-174	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MEFHIKGN_02596	2.41e-150	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MEFHIKGN_02597	3.82e-167	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MEFHIKGN_02598	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
MEFHIKGN_02599	3.44e-201	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
MEFHIKGN_02600	1.21e-268	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MEFHIKGN_02601	9.87e-132	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
MEFHIKGN_02602	2.28e-63	yxiS	-	-	-	-	-	-	-
MEFHIKGN_02603	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MEFHIKGN_02604	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MEFHIKGN_02605	7.21e-183	bglS	-	-	M	-	-	-	licheninase activity
MEFHIKGN_02606	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MEFHIKGN_02607	7.23e-141	-	-	-	-	-	-	-	-
MEFHIKGN_02608	1.55e-291	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
MEFHIKGN_02609	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MEFHIKGN_02610	4.4e-268	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MEFHIKGN_02611	1.31e-70	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MEFHIKGN_02612	6.89e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
MEFHIKGN_02615	3.48e-59	yxiJ	-	-	S	-	-	-	YxiJ-like protein
MEFHIKGN_02616	3.23e-108	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
MEFHIKGN_02617	5.7e-210	yxxF	-	-	EG	-	-	-	EamA-like transporter family
MEFHIKGN_02618	1.21e-163	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEFHIKGN_02619	4.54e-157	-	1.14.11.45	-	E	ko:K20418	-	ko00000,ko01000	2OG-Fe dioxygenase
MEFHIKGN_02620	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
MEFHIKGN_02621	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MEFHIKGN_02622	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MEFHIKGN_02623	8.25e-69	-	-	-	-	-	-	-	-
MEFHIKGN_02624	1.08e-63	-	-	-	-	-	-	-	-
MEFHIKGN_02625	0.0	-	-	-	S	-	-	-	nuclease activity
MEFHIKGN_02626	1.33e-52	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
MEFHIKGN_02627	5.09e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
MEFHIKGN_02628	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MEFHIKGN_02629	4.54e-13	-	-	-	S	-	-	-	Oxidoreductase
MEFHIKGN_02631	5.13e-16	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
MEFHIKGN_02632	3.34e-101	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MEFHIKGN_02633	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
MEFHIKGN_02634	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MEFHIKGN_02635	6.14e-297	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
MEFHIKGN_02636	3.41e-231	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MEFHIKGN_02637	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MEFHIKGN_02638	5.47e-297	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
MEFHIKGN_02639	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MEFHIKGN_02640	3.38e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MEFHIKGN_02641	1.22e-221	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MEFHIKGN_02642	2.51e-195	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
MEFHIKGN_02643	2.8e-109	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
MEFHIKGN_02644	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MEFHIKGN_02646	5.36e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
MEFHIKGN_02647	3.54e-178	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
MEFHIKGN_02648	1.01e-227	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEFHIKGN_02649	5.81e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEFHIKGN_02650	5.12e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
MEFHIKGN_02651	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
MEFHIKGN_02652	8.14e-303	ybbC	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_02653	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
MEFHIKGN_02654	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
MEFHIKGN_02655	5.99e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MEFHIKGN_02656	5.43e-194	ybbH	-	-	K	-	-	-	transcriptional
MEFHIKGN_02657	1.35e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MEFHIKGN_02658	6.32e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
MEFHIKGN_02659	2.43e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
MEFHIKGN_02665	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MEFHIKGN_02666	3.19e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MEFHIKGN_02667	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MEFHIKGN_02668	1.44e-290	ybbR	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_02669	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MEFHIKGN_02670	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEFHIKGN_02671	2.67e-220	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MEFHIKGN_02672	6.2e-155	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
MEFHIKGN_02673	3.69e-129	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MEFHIKGN_02674	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MEFHIKGN_02675	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
MEFHIKGN_02676	1.34e-118	ybcF	-	-	P	-	-	-	carbonic anhydrase
MEFHIKGN_02678	4.6e-63	-	-	-	-	-	-	-	-
MEFHIKGN_02679	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MEFHIKGN_02680	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
MEFHIKGN_02681	7.69e-257	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MEFHIKGN_02683	7.24e-304	-	-	-	J	-	-	-	4Fe-4S single cluster domain
MEFHIKGN_02684	0.0	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
MEFHIKGN_02685	8.07e-174	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MEFHIKGN_02686	3.99e-313	skfF	-	-	S	-	-	-	ABC transporter
MEFHIKGN_02687	3.88e-118	-	-	-	C	-	-	-	HEAT repeats
MEFHIKGN_02688	1.97e-101	-	-	-	CO	-	-	-	Thioredoxin-like domain
MEFHIKGN_02689	2.31e-232	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MEFHIKGN_02690	1.39e-157	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
MEFHIKGN_02691	4.22e-214	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
MEFHIKGN_02693	1.68e-179	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MEFHIKGN_02694	1.49e-192	ybdN	-	-	-	-	-	-	-
MEFHIKGN_02695	8.98e-274	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
MEFHIKGN_02696	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MEFHIKGN_02697	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
MEFHIKGN_02698	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
MEFHIKGN_02699	5.27e-193	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
MEFHIKGN_02700	2.67e-314	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
MEFHIKGN_02701	1.11e-54	ybyB	-	-	-	-	-	-	-
MEFHIKGN_02702	0.0	ybeC	-	-	E	-	-	-	amino acid
MEFHIKGN_02703	5.76e-210	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
MEFHIKGN_02704	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
MEFHIKGN_02705	3.57e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MEFHIKGN_02706	2.1e-218	ybfA	-	-	K	-	-	-	FR47-like protein
MEFHIKGN_02707	2.75e-286	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_02709	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
MEFHIKGN_02710	5.27e-208	ybfH	-	-	EG	-	-	-	EamA-like transporter family
MEFHIKGN_02711	6.07e-187	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
MEFHIKGN_02712	5.85e-274	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MEFHIKGN_02713	5.04e-230	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
MEFHIKGN_02715	3.91e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MEFHIKGN_02716	5.67e-123	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEFHIKGN_02717	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
MEFHIKGN_02718	2.06e-188	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MEFHIKGN_02719	1.58e-59	ybfN	-	-	-	-	-	-	-
MEFHIKGN_02720	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
MEFHIKGN_02721	1.16e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
MEFHIKGN_02722	4.96e-272	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEFHIKGN_02723	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MEFHIKGN_02724	2.12e-174	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MEFHIKGN_02725	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MEFHIKGN_02727	9.43e-259	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MEFHIKGN_02728	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MEFHIKGN_02729	1.51e-232	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
MEFHIKGN_02731	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MEFHIKGN_02732	4.35e-238	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MEFHIKGN_02733	1.96e-291	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_02734	7.01e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
MEFHIKGN_02735	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
MEFHIKGN_02736	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MEFHIKGN_02737	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_02738	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MEFHIKGN_02739	4.44e-159	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MEFHIKGN_02740	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MEFHIKGN_02741	2.37e-220	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
MEFHIKGN_02742	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
MEFHIKGN_02743	4.02e-134	eamA1	-	-	EG	-	-	-	spore germination
MEFHIKGN_02744	3.05e-159	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEFHIKGN_02745	6.48e-216	ycbM	-	-	T	-	-	-	Histidine kinase
MEFHIKGN_02746	2.64e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_02747	4.75e-147	-	-	-	S	-	-	-	ABC-2 family transporter protein
MEFHIKGN_02748	1.82e-75	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MEFHIKGN_02749	1.82e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
MEFHIKGN_02750	5.44e-174	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
MEFHIKGN_02751	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
MEFHIKGN_02752	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MEFHIKGN_02753	3.09e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MEFHIKGN_02754	1.2e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MEFHIKGN_02755	2.22e-257	ycbU	-	-	E	-	-	-	Selenocysteine lyase
MEFHIKGN_02756	2.87e-308	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MEFHIKGN_02757	6.54e-132	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MEFHIKGN_02758	7.18e-259	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MEFHIKGN_02759	4e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MEFHIKGN_02760	4.65e-73	-	-	-	S	-	-	-	RDD family
MEFHIKGN_02761	6.84e-253	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
MEFHIKGN_02762	1.77e-212	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MEFHIKGN_02763	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MEFHIKGN_02764	2.2e-170	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MEFHIKGN_02765	6.57e-256	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MEFHIKGN_02766	2.9e-28	yccK	-	-	C	-	-	-	Aldo keto reductase
MEFHIKGN_02767	1.29e-182	yccK	-	-	C	-	-	-	Aldo keto reductase
MEFHIKGN_02768	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
MEFHIKGN_02769	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MEFHIKGN_02770	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MEFHIKGN_02771	1.53e-122	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MEFHIKGN_02772	3.33e-247	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
MEFHIKGN_02773	6.85e-180	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
MEFHIKGN_02774	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MEFHIKGN_02775	1.95e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MEFHIKGN_02776	1.99e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MEFHIKGN_02777	4.63e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MEFHIKGN_02778	9.18e-242	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEFHIKGN_02779	2.64e-141	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
MEFHIKGN_02780	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MEFHIKGN_02781	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MEFHIKGN_02782	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
MEFHIKGN_02783	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
MEFHIKGN_02784	4.21e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
MEFHIKGN_02785	6.36e-277	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
MEFHIKGN_02786	1.17e-267	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MEFHIKGN_02787	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MEFHIKGN_02788	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
MEFHIKGN_02789	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MEFHIKGN_02790	2.01e-210	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MEFHIKGN_02791	9.75e-277	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
MEFHIKGN_02792	0.0	ycgA	-	-	S	-	-	-	Membrane
MEFHIKGN_02793	2.72e-105	ycgB	-	-	-	-	-	-	-
MEFHIKGN_02794	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
MEFHIKGN_02795	1.19e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MEFHIKGN_02796	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MEFHIKGN_02797	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
MEFHIKGN_02798	3.7e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MEFHIKGN_02799	6.42e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
MEFHIKGN_02800	6.19e-194	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
MEFHIKGN_02801	0.0	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MEFHIKGN_02802	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
MEFHIKGN_02803	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MEFHIKGN_02804	3.09e-139	tmrB	-	-	S	-	-	-	AAA domain
MEFHIKGN_02806	1.05e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MEFHIKGN_02807	1.29e-186	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MEFHIKGN_02808	5.4e-226	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
MEFHIKGN_02809	4.48e-231	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MEFHIKGN_02810	7.76e-187	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
MEFHIKGN_02811	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MEFHIKGN_02812	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MEFHIKGN_02813	2.64e-316	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEFHIKGN_02814	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
MEFHIKGN_02815	1.1e-194	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
MEFHIKGN_02816	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
MEFHIKGN_02817	3.59e-204	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
MEFHIKGN_02818	1.48e-245	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MEFHIKGN_02819	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MEFHIKGN_02820	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
MEFHIKGN_02821	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MEFHIKGN_02822	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MEFHIKGN_02823	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
MEFHIKGN_02824	2.62e-281	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MEFHIKGN_02825	2.03e-220	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
MEFHIKGN_02826	2.99e-140	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MEFHIKGN_02827	1.71e-284	yciC	-	-	S	-	-	-	GTPases (G3E family)
MEFHIKGN_02828	1.22e-148	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MEFHIKGN_02829	2.08e-184	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MEFHIKGN_02832	2.83e-99	yckC	-	-	S	-	-	-	membrane
MEFHIKGN_02833	1.01e-68	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
MEFHIKGN_02834	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MEFHIKGN_02835	4.78e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
MEFHIKGN_02836	3.23e-99	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MEFHIKGN_02837	4.34e-267	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MEFHIKGN_02838	3.24e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MEFHIKGN_02839	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
MEFHIKGN_02840	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
MEFHIKGN_02841	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEFHIKGN_02842	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEFHIKGN_02843	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
MEFHIKGN_02844	9.45e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
MEFHIKGN_02845	6.26e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MEFHIKGN_02846	4.25e-122	-	-	-	S	-	-	-	YcxB-like protein
MEFHIKGN_02847	3.27e-205	ycxC	-	-	EG	-	-	-	EamA-like transporter family
MEFHIKGN_02848	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
MEFHIKGN_02849	4.76e-145	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
MEFHIKGN_02850	8.71e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
MEFHIKGN_02851	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MEFHIKGN_02852	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MEFHIKGN_02853	7.14e-187	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MEFHIKGN_02854	5.32e-209	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
MEFHIKGN_02855	5.28e-139	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MEFHIKGN_02856	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MEFHIKGN_02857	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
MEFHIKGN_02858	5.92e-107	yclD	-	-	-	-	-	-	-
MEFHIKGN_02859	9.51e-203	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
MEFHIKGN_02860	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
MEFHIKGN_02861	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
MEFHIKGN_02863	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
MEFHIKGN_02864	1.22e-289	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
MEFHIKGN_02865	4.24e-250	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
MEFHIKGN_02866	3.39e-155	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MEFHIKGN_02867	2.59e-274	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
MEFHIKGN_02868	2.23e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEFHIKGN_02869	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MEFHIKGN_02870	3.09e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MEFHIKGN_02872	6.5e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MEFHIKGN_02873	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MEFHIKGN_02874	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEFHIKGN_02875	4.69e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEFHIKGN_02876	3.26e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_02877	4.98e-223	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
MEFHIKGN_02878	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
MEFHIKGN_02879	9.73e-197	ycnC	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02880	2.12e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MEFHIKGN_02881	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
MEFHIKGN_02882	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MEFHIKGN_02883	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MEFHIKGN_02884	7.68e-310	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MEFHIKGN_02885	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MEFHIKGN_02886	3.37e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
MEFHIKGN_02887	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEFHIKGN_02888	3.05e-138	ycnI	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_02889	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
MEFHIKGN_02890	5.18e-139	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MEFHIKGN_02891	1.34e-74	-	-	-	-	-	-	-	-
MEFHIKGN_02892	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
MEFHIKGN_02893	2.38e-94	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MEFHIKGN_02894	2.97e-266	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
MEFHIKGN_02895	1.01e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
MEFHIKGN_02897	1.78e-96	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MEFHIKGN_02898	1.71e-143	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
MEFHIKGN_02899	1.89e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MEFHIKGN_02901	1.1e-176	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MEFHIKGN_02902	1.1e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
MEFHIKGN_02903	2.78e-273	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
MEFHIKGN_02904	8.18e-189	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
MEFHIKGN_02905	1.19e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
MEFHIKGN_02906	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
MEFHIKGN_02907	1.81e-169	kipR	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_02908	4.89e-153	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
MEFHIKGN_02910	7.67e-66	yczJ	-	-	S	-	-	-	biosynthesis
MEFHIKGN_02911	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
MEFHIKGN_02912	8.6e-220	ycsN	-	-	S	-	-	-	Oxidoreductase
MEFHIKGN_02913	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
MEFHIKGN_02914	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
MEFHIKGN_02915	1.53e-122	ydaC	-	-	Q	-	-	-	Methyltransferase domain
MEFHIKGN_02916	8.81e-206	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEFHIKGN_02917	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
MEFHIKGN_02918	1.33e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MEFHIKGN_02919	5.24e-101	ydaG	-	-	S	-	-	-	general stress protein
MEFHIKGN_02920	2.65e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MEFHIKGN_02921	3.12e-61	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
MEFHIKGN_02922	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MEFHIKGN_02923	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEFHIKGN_02924	5.97e-265	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MEFHIKGN_02925	1.56e-193	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
MEFHIKGN_02926	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
MEFHIKGN_02927	1.12e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
MEFHIKGN_02928	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
MEFHIKGN_02929	0.0	ydaO	-	-	E	-	-	-	amino acid
MEFHIKGN_02930	2.28e-86	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MEFHIKGN_02931	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MEFHIKGN_02932	2.5e-52	-	-	-	-	-	-	-	-
MEFHIKGN_02933	3.9e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MEFHIKGN_02934	1.67e-42	ydaS	-	-	S	-	-	-	membrane
MEFHIKGN_02935	2.25e-100	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MEFHIKGN_02936	9.72e-187	ydbA	-	-	P	-	-	-	EcsC protein family
MEFHIKGN_02937	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
MEFHIKGN_02938	3.09e-78	ydbB	-	-	G	-	-	-	Cupin domain
MEFHIKGN_02939	1.49e-81	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
MEFHIKGN_02940	1.06e-195	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
MEFHIKGN_02941	1.49e-252	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MEFHIKGN_02942	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MEFHIKGN_02943	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MEFHIKGN_02944	8.93e-290	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEFHIKGN_02945	1.32e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
MEFHIKGN_02946	2.28e-219	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_02947	4.25e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MEFHIKGN_02948	9.32e-70	ydbL	-	-	-	-	-	-	-
MEFHIKGN_02949	6.12e-279	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
MEFHIKGN_02950	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
MEFHIKGN_02951	2.1e-11	-	-	-	S	-	-	-	Fur-regulated basic protein A
MEFHIKGN_02952	2.72e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEFHIKGN_02953	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
MEFHIKGN_02954	8.43e-256	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MEFHIKGN_02955	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MEFHIKGN_02956	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MEFHIKGN_02957	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
MEFHIKGN_02958	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
MEFHIKGN_02959	2.96e-138	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
MEFHIKGN_02960	1.6e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MEFHIKGN_02961	1.9e-233	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
MEFHIKGN_02962	5.92e-281	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEFHIKGN_02963	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MEFHIKGN_02964	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MEFHIKGN_02965	2.46e-183	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
MEFHIKGN_02966	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
MEFHIKGN_02967	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MEFHIKGN_02968	1.86e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
MEFHIKGN_02969	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
MEFHIKGN_02970	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MEFHIKGN_02971	5.17e-177	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEFHIKGN_02972	1.86e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
MEFHIKGN_02973	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
MEFHIKGN_02974	3.74e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MEFHIKGN_02982	3.99e-96	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MEFHIKGN_02983	2.01e-58	-	-	-	-	-	-	-	-
MEFHIKGN_02984	5.86e-38	-	-	-	S	-	-	-	LXG domain of WXG superfamily
MEFHIKGN_02985	8.43e-29	-	-	-	L	ko:K07451,ko:K07452	-	ko00000,ko01000,ko02048	HNH endonuclease
MEFHIKGN_02986	9.05e-56	-	-	-	L	-	-	-	HNH nucleases
MEFHIKGN_02989	7.24e-08	-	-	-	S	-	-	-	Putative amidase domain
MEFHIKGN_02993	1.54e-46	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MEFHIKGN_02994	6e-53	-	-	-	-	-	-	-	-
MEFHIKGN_02998	1e-144	ydeA	-	-	S	-	-	-	DJ-1/PfpI family
MEFHIKGN_02999	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
MEFHIKGN_03000	3.57e-103	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
MEFHIKGN_03001	8e-181	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MEFHIKGN_03002	6.25e-213	-	-	-	K	-	-	-	AraC-like ligand binding domain
MEFHIKGN_03003	2.65e-219	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MEFHIKGN_03004	7.88e-211	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
MEFHIKGN_03005	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MEFHIKGN_03006	1.54e-276	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
MEFHIKGN_03007	7.55e-69	ydeH	-	-	-	-	-	-	-
MEFHIKGN_03008	3.6e-83	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
MEFHIKGN_03009	6.79e-139	-	-	-	-	-	-	-	-
MEFHIKGN_03010	1.1e-39	-	-	-	S	-	-	-	SNARE associated Golgi protein
MEFHIKGN_03011	1.64e-19	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
MEFHIKGN_03012	4.22e-111	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MEFHIKGN_03013	4.66e-197	ydeK	-	-	EG	-	-	-	-transporter
MEFHIKGN_03014	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MEFHIKGN_03015	3.68e-97	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
MEFHIKGN_03016	1.43e-136	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
MEFHIKGN_03017	2.91e-72	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MEFHIKGN_03018	6.56e-194	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MEFHIKGN_03019	2.92e-90	ydeP	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_03020	1e-144	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	NADPH-quinone reductase (modulator of drug activity B)
MEFHIKGN_03021	1.96e-257	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MEFHIKGN_03022	9.96e-135	ydeS	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_03023	1.22e-74	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
MEFHIKGN_03024	1.06e-295	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MEFHIKGN_03025	8.05e-191	-	-	-	J	-	-	-	GNAT acetyltransferase
MEFHIKGN_03026	3.05e-207	-	-	-	EG	-	-	-	EamA-like transporter family
MEFHIKGN_03027	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MEFHIKGN_03028	6.97e-150	ydfE	-	-	S	-	-	-	Flavin reductase like domain
MEFHIKGN_03029	5.24e-159	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MEFHIKGN_03030	1.37e-104	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MEFHIKGN_03032	4.11e-253	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_03033	2.3e-142	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEFHIKGN_03034	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
MEFHIKGN_03035	9.73e-226	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MEFHIKGN_03036	6.79e-152	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MEFHIKGN_03037	2.13e-189	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
MEFHIKGN_03038	3.15e-200	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEFHIKGN_03039	3.45e-145	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
MEFHIKGN_03040	3.18e-237	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MEFHIKGN_03041	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
MEFHIKGN_03042	3.11e-73	ydfQ	-	-	CO	-	-	-	Thioredoxin
MEFHIKGN_03043	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MEFHIKGN_03044	5.33e-39	-	-	-	-	-	-	-	-
MEFHIKGN_03046	6.08e-153	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
MEFHIKGN_03047	4.44e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
MEFHIKGN_03048	3.13e-99	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MEFHIKGN_03049	2.74e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MEFHIKGN_03050	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MEFHIKGN_03051	5.75e-128	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MEFHIKGN_03052	6.73e-69	-	-	-	S	-	-	-	DoxX-like family
MEFHIKGN_03053	4.66e-110	yycN	-	-	K	-	-	-	Acetyltransferase
MEFHIKGN_03054	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
MEFHIKGN_03055	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MEFHIKGN_03056	1.46e-118	-	-	-	S	-	-	-	DinB family
MEFHIKGN_03057	2.06e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MEFHIKGN_03058	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
MEFHIKGN_03059	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
MEFHIKGN_03060	3.29e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MEFHIKGN_03061	9.89e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MEFHIKGN_03062	1.77e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MEFHIKGN_03063	5.24e-158	ydhC	-	-	K	-	-	-	FCD
MEFHIKGN_03064	1.73e-307	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
MEFHIKGN_03065	7.9e-289	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MEFHIKGN_03066	1.67e-160	-	-	-	-	-	-	-	-
MEFHIKGN_03067	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MEFHIKGN_03068	2.74e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MEFHIKGN_03070	2.11e-107	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MEFHIKGN_03071	1.28e-229	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MEFHIKGN_03072	1.15e-127	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
MEFHIKGN_03073	6.3e-255	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MEFHIKGN_03074	7.97e-65	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MEFHIKGN_03075	1.44e-68	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MEFHIKGN_03076	2.27e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEFHIKGN_03077	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MEFHIKGN_03078	7.75e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MEFHIKGN_03079	3.34e-212	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
MEFHIKGN_03080	5.09e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MEFHIKGN_03081	8.23e-272	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
MEFHIKGN_03082	4.02e-201	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
MEFHIKGN_03101	2.22e-185	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
MEFHIKGN_03102	3.88e-37	-	-	-	-	-	-	-	-
MEFHIKGN_03103	4.02e-172	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
MEFHIKGN_03104	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MEFHIKGN_03105	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
MEFHIKGN_03107	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MEFHIKGN_03108	6.86e-184	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MEFHIKGN_03109	1.7e-217	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
MEFHIKGN_03110	5.86e-190	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MEFHIKGN_03111	5.41e-275	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
MEFHIKGN_03113	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEFHIKGN_03114	2.79e-102	ygaO	-	-	-	-	-	-	-
MEFHIKGN_03115	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_03117	1.92e-147	yhzB	-	-	S	-	-	-	B3/4 domain
MEFHIKGN_03118	1.7e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MEFHIKGN_03119	9.27e-224	yhbB	-	-	S	-	-	-	Putative amidase domain
MEFHIKGN_03120	1.08e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MEFHIKGN_03121	5.64e-142	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
MEFHIKGN_03122	1.32e-95	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MEFHIKGN_03123	7.04e-104	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MEFHIKGN_03124	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
MEFHIKGN_03125	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
MEFHIKGN_03126	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
MEFHIKGN_03127	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
MEFHIKGN_03128	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MEFHIKGN_03129	9.84e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
MEFHIKGN_03130	3.95e-59	yhcC	-	-	-	-	-	-	-
MEFHIKGN_03131	1.18e-68	-	-	-	-	-	-	-	-
MEFHIKGN_03132	4.78e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_03133	3.24e-156	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_03134	4.37e-211	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_03135	3.45e-212	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MEFHIKGN_03136	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MEFHIKGN_03137	1.34e-195	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MEFHIKGN_03138	7.08e-251	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
MEFHIKGN_03139	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEFHIKGN_03140	1.13e-70	yhcM	-	-	-	-	-	-	-
MEFHIKGN_03141	6.46e-103	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MEFHIKGN_03142	1.19e-195	yhcP	-	-	-	-	-	-	-
MEFHIKGN_03143	1.68e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
MEFHIKGN_03144	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MEFHIKGN_03145	1.52e-135	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MEFHIKGN_03146	2.76e-217	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MEFHIKGN_03147	2.47e-88	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
MEFHIKGN_03148	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
MEFHIKGN_03149	3.04e-155	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
MEFHIKGN_03150	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MEFHIKGN_03151	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MEFHIKGN_03152	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MEFHIKGN_03153	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MEFHIKGN_03154	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MEFHIKGN_03155	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MEFHIKGN_03156	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
MEFHIKGN_03157	1.54e-271	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_03158	9.41e-145	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEFHIKGN_03159	4.67e-116	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
MEFHIKGN_03160	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
MEFHIKGN_03161	1.25e-72	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MEFHIKGN_03162	5.63e-274	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MEFHIKGN_03163	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
MEFHIKGN_03164	7.16e-305	ygxB	-	-	M	-	-	-	Conserved TM helix
MEFHIKGN_03165	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
MEFHIKGN_03166	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MEFHIKGN_03167	1.05e-199	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MEFHIKGN_03168	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_03169	1.51e-260	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MEFHIKGN_03170	5.51e-206	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEFHIKGN_03171	8.94e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
MEFHIKGN_03172	5e-309	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MEFHIKGN_03173	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MEFHIKGN_03174	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEFHIKGN_03175	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
MEFHIKGN_03176	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
MEFHIKGN_03177	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MEFHIKGN_03178	6.74e-244	yhdN	-	-	C	-	-	-	Aldo keto reductase
MEFHIKGN_03179	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MEFHIKGN_03180	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MEFHIKGN_03181	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
MEFHIKGN_03182	1.03e-283	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MEFHIKGN_03183	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MEFHIKGN_03184	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEFHIKGN_03185	5.83e-87	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEFHIKGN_03186	7.42e-172	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MEFHIKGN_03187	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
MEFHIKGN_03188	3.04e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
MEFHIKGN_03189	3.28e-177	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MEFHIKGN_03190	2.14e-195	nodB1	-	-	G	-	-	-	deacetylase
MEFHIKGN_03191	3.69e-196	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MEFHIKGN_03192	1.18e-295	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MEFHIKGN_03193	1.29e-107	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
MEFHIKGN_03194	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MEFHIKGN_03195	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MEFHIKGN_03196	3.86e-142	yheG	-	-	GM	-	-	-	NAD(P)H-binding
MEFHIKGN_03197	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
MEFHIKGN_03198	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
MEFHIKGN_03199	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MEFHIKGN_03200	3.37e-276	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MEFHIKGN_03201	2.4e-258	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
MEFHIKGN_03202	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MEFHIKGN_03203	1.58e-262	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
MEFHIKGN_03204	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MEFHIKGN_03205	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
MEFHIKGN_03206	2.63e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
MEFHIKGN_03207	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MEFHIKGN_03209	1.32e-171	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
MEFHIKGN_03210	1.1e-34	-	-	-	S	-	-	-	YhzD-like protein
MEFHIKGN_03211	5.56e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_03212	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
MEFHIKGN_03213	1.34e-300	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
MEFHIKGN_03214	0.0	yhaN	-	-	L	-	-	-	AAA domain
MEFHIKGN_03215	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
MEFHIKGN_03216	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
MEFHIKGN_03217	6.57e-179	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MEFHIKGN_03218	1.4e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
MEFHIKGN_03219	8.48e-73	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
MEFHIKGN_03220	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
MEFHIKGN_03221	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
MEFHIKGN_03222	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
MEFHIKGN_03223	2.06e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MEFHIKGN_03224	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MEFHIKGN_03225	1.1e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
MEFHIKGN_03226	1.27e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MEFHIKGN_03227	1.18e-160	ecsC	-	-	S	-	-	-	EcsC protein family
MEFHIKGN_03228	8.91e-291	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MEFHIKGN_03229	8.08e-316	yhfA	-	-	C	-	-	-	membrane
MEFHIKGN_03230	1.33e-23	-	-	-	C	-	-	-	Rubrerythrin
MEFHIKGN_03231	2.18e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MEFHIKGN_03232	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MEFHIKGN_03233	1.06e-258	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MEFHIKGN_03234	3.99e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MEFHIKGN_03235	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MEFHIKGN_03236	5.79e-132	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_03237	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
MEFHIKGN_03238	4.87e-234	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEFHIKGN_03239	1.61e-178	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
MEFHIKGN_03240	2.68e-253	yhfE	-	-	G	-	-	-	peptidase M42
MEFHIKGN_03241	6.22e-93	-	-	-	S	-	-	-	ASCH
MEFHIKGN_03242	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEFHIKGN_03243	2.82e-181	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MEFHIKGN_03244	4.06e-245	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MEFHIKGN_03245	1.01e-141	yhfK	-	-	GM	-	-	-	NmrA-like family
MEFHIKGN_03246	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MEFHIKGN_03247	6.55e-84	yhfM	-	-	-	-	-	-	-
MEFHIKGN_03248	3.92e-307	yhfN	-	-	O	-	-	-	Peptidase M48
MEFHIKGN_03249	2.81e-259	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MEFHIKGN_03250	1.86e-103	-	-	-	K	-	-	-	acetyltransferase
MEFHIKGN_03251	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
MEFHIKGN_03252	2.77e-223	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MEFHIKGN_03253	9.64e-141	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
MEFHIKGN_03254	4.96e-249	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MEFHIKGN_03255	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MEFHIKGN_03256	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MEFHIKGN_03257	2.62e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
MEFHIKGN_03258	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
MEFHIKGN_03259	7.82e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEFHIKGN_03260	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
MEFHIKGN_03261	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
MEFHIKGN_03262	2.55e-216	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MEFHIKGN_03263	4.64e-53	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
MEFHIKGN_03264	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEFHIKGN_03265	6.55e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MEFHIKGN_03266	4.13e-78	yhjD	-	-	-	-	-	-	-
MEFHIKGN_03267	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
MEFHIKGN_03268	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MEFHIKGN_03269	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
MEFHIKGN_03270	4.68e-121	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MEFHIKGN_03271	1.73e-270	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
MEFHIKGN_03272	5.2e-253	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MEFHIKGN_03273	2.52e-203	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
MEFHIKGN_03274	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MEFHIKGN_03275	4.36e-239	yhjM	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_03276	1.02e-258	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
MEFHIKGN_03277	1.93e-267	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MEFHIKGN_03278	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
MEFHIKGN_03279	1.29e-70	yhjQ	-	-	C	-	-	-	COG1145 Ferredoxin
MEFHIKGN_03280	9.3e-102	yhjR	-	-	S	-	-	-	Rubrerythrin
MEFHIKGN_03281	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
MEFHIKGN_03282	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MEFHIKGN_03283	5.69e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MEFHIKGN_03284	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
MEFHIKGN_03285	6.4e-65	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
MEFHIKGN_03286	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
MEFHIKGN_03287	3.35e-87	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
MEFHIKGN_03288	7.36e-34	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
MEFHIKGN_03289	2.88e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
MEFHIKGN_03290	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
MEFHIKGN_03291	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
MEFHIKGN_03292	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MEFHIKGN_03293	2.29e-223	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MEFHIKGN_03294	7.64e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MEFHIKGN_03295	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
MEFHIKGN_03296	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MEFHIKGN_03297	4.12e-129	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
MEFHIKGN_03298	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MEFHIKGN_03299	7.21e-105	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
MEFHIKGN_03300	4.6e-191	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
MEFHIKGN_03301	1.01e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
MEFHIKGN_03302	3.88e-205	yisR	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_03303	1.83e-235	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MEFHIKGN_03304	6.75e-245	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MEFHIKGN_03305	4.92e-120	yisT	-	-	S	-	-	-	DinB family
MEFHIKGN_03306	1.28e-138	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
MEFHIKGN_03307	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MEFHIKGN_03308	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
MEFHIKGN_03309	2.25e-199	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MEFHIKGN_03310	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MEFHIKGN_03311	3.23e-294	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MEFHIKGN_03312	3.87e-184	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MEFHIKGN_03313	1.34e-162	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
MEFHIKGN_03314	4.31e-180	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
MEFHIKGN_03315	6.77e-145	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEFHIKGN_03316	2.14e-283	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MEFHIKGN_03317	1.01e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_03318	1.4e-200	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MEFHIKGN_03319	5.09e-92	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MEFHIKGN_03320	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MEFHIKGN_03321	4.29e-77	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
MEFHIKGN_03322	2.75e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
MEFHIKGN_03323	4.16e-122	-	-	-	-	-	-	-	-
MEFHIKGN_03324	1.17e-217	-	-	-	-	-	-	-	-
MEFHIKGN_03325	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
MEFHIKGN_03326	2.08e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MEFHIKGN_03327	2.13e-120	-	-	-	-	-	-	-	-
MEFHIKGN_03328	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
MEFHIKGN_03329	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MEFHIKGN_03330	9.13e-202	yitS	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_03331	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MEFHIKGN_03332	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
MEFHIKGN_03333	4.11e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
MEFHIKGN_03334	1.92e-08	-	-	-	-	-	-	-	-
MEFHIKGN_03335	3.19e-200	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MEFHIKGN_03336	5.05e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MEFHIKGN_03337	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
MEFHIKGN_03338	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
MEFHIKGN_03339	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
MEFHIKGN_03340	3.24e-114	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
MEFHIKGN_03341	7.41e-255	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MEFHIKGN_03342	7.4e-295	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MEFHIKGN_03343	5.4e-177	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MEFHIKGN_03344	1.69e-278	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
MEFHIKGN_03345	1.4e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MEFHIKGN_03346	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
MEFHIKGN_03347	3.01e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MEFHIKGN_03348	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
MEFHIKGN_03349	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MEFHIKGN_03350	5.69e-181	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
MEFHIKGN_03351	5.2e-132	yjaV	-	-	-	-	-	-	-
MEFHIKGN_03352	6.4e-235	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
MEFHIKGN_03353	8.86e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
MEFHIKGN_03354	2.67e-38	yjzB	-	-	-	-	-	-	-
MEFHIKGN_03355	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEFHIKGN_03356	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEFHIKGN_03357	9.48e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
MEFHIKGN_03358	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MEFHIKGN_03359	2.07e-237	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MEFHIKGN_03360	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MEFHIKGN_03361	6.73e-216	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEFHIKGN_03362	3.49e-196	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEFHIKGN_03363	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
MEFHIKGN_03364	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
MEFHIKGN_03365	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MEFHIKGN_03366	1.03e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEFHIKGN_03367	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEFHIKGN_03368	3.22e-248	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MEFHIKGN_03369	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MEFHIKGN_03370	1.18e-267	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
MEFHIKGN_03371	2.65e-133	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEFHIKGN_03372	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MEFHIKGN_03373	2.03e-143	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
MEFHIKGN_03374	6.34e-147	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MEFHIKGN_03375	1.03e-280	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MEFHIKGN_03376	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MEFHIKGN_03377	2.68e-28	-	-	-	-	-	-	-	-
MEFHIKGN_03379	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MEFHIKGN_03380	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
MEFHIKGN_03381	2.94e-128	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MEFHIKGN_03382	7.32e-130	yjbK	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_03383	3.77e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
MEFHIKGN_03384	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
MEFHIKGN_03385	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEFHIKGN_03386	1.49e-202	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MEFHIKGN_03387	8.09e-181	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MEFHIKGN_03388	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEFHIKGN_03389	5.7e-177	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MEFHIKGN_03390	4.01e-139	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
MEFHIKGN_03391	1.09e-275	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
MEFHIKGN_03392	2.18e-41	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
MEFHIKGN_03393	6.78e-174	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MEFHIKGN_03394	7.21e-237	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MEFHIKGN_03395	3.98e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MEFHIKGN_03396	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MEFHIKGN_03397	3.63e-104	yjbX	-	-	S	-	-	-	Spore coat protein
MEFHIKGN_03398	3.92e-107	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
MEFHIKGN_03399	6.3e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
MEFHIKGN_03400	1.23e-95	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
MEFHIKGN_03401	9.3e-32	cotW	-	-	-	ko:K06341	-	ko00000	-
MEFHIKGN_03402	2.34e-66	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
MEFHIKGN_03403	1.23e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MEFHIKGN_03406	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
MEFHIKGN_03407	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MEFHIKGN_03408	6.31e-51	-	-	-	-	-	-	-	-
MEFHIKGN_03409	1.1e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEFHIKGN_03410	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
MEFHIKGN_03411	1.83e-175	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
MEFHIKGN_03413	1.87e-163	-	-	-	V	-	-	-	COG1401 GTPase subunit of restriction endonuclease
MEFHIKGN_03414	8.47e-88	-	-	-	-	-	-	-	-
MEFHIKGN_03415	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MEFHIKGN_03416	2.14e-279	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MEFHIKGN_03417	6.86e-126	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
MEFHIKGN_03418	1.37e-269	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
MEFHIKGN_03421	3.75e-269	-	-	-	S	-	-	-	Putative amidase domain
MEFHIKGN_03422	1.52e-68	yjcN	-	-	-	-	-	-	-
MEFHIKGN_03424	1.84e-105	-	-	-	L	-	-	-	Transposase
MEFHIKGN_03426	2.93e-81	yqaS	-	-	L	-	-	-	DNA packaging
MEFHIKGN_03427	1.27e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MEFHIKGN_03428	6.61e-179	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MEFHIKGN_03429	0.000759	-	-	-	-	-	-	-	-
MEFHIKGN_03430	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
MEFHIKGN_03431	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MEFHIKGN_03432	6.2e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MEFHIKGN_03433	3.93e-77	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
MEFHIKGN_03434	2.09e-116	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MEFHIKGN_03436	2.38e-104	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MEFHIKGN_03437	3.55e-39	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
MEFHIKGN_03438	2.31e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
MEFHIKGN_03439	1.77e-222	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MEFHIKGN_03441	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MEFHIKGN_03442	6.11e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
MEFHIKGN_03443	1.13e-29	yjfB	-	-	S	-	-	-	Putative motility protein
MEFHIKGN_03444	1.12e-210	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
MEFHIKGN_03445	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
MEFHIKGN_03446	4.96e-133	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
MEFHIKGN_03447	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
MEFHIKGN_03448	1.6e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MEFHIKGN_03450	1.06e-146	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MEFHIKGN_03452	1.58e-284	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MEFHIKGN_03453	8.74e-280	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MEFHIKGN_03454	1.11e-41	-	-	-	-	-	-	-	-
MEFHIKGN_03455	1.01e-185	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MEFHIKGN_03456	1.5e-154	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
MEFHIKGN_03457	2.3e-174	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MEFHIKGN_03458	2.99e-223	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
MEFHIKGN_03459	2.46e-118	yjlB	-	-	S	-	-	-	Cupin domain
MEFHIKGN_03460	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MEFHIKGN_03461	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MEFHIKGN_03462	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
MEFHIKGN_03463	2.5e-313	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
MEFHIKGN_03464	1.71e-240	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
MEFHIKGN_03465	1.71e-241	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
MEFHIKGN_03466	1.37e-273	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
MEFHIKGN_03467	1.34e-196	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFHIKGN_03468	1.37e-289	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
MEFHIKGN_03469	8.11e-237	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MEFHIKGN_03470	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
MEFHIKGN_03471	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MEFHIKGN_03472	1.59e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MEFHIKGN_03473	4.68e-104	yjoA	-	-	S	-	-	-	DinB family
MEFHIKGN_03474	2.48e-313	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
MEFHIKGN_03475	8.59e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MEFHIKGN_03477	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
MEFHIKGN_03478	5.34e-218	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MEFHIKGN_03479	1.35e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
MEFHIKGN_03480	1.47e-143	yjqB	-	-	S	-	-	-	Pfam:DUF867
MEFHIKGN_03481	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
MEFHIKGN_03482	7.3e-143	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MEFHIKGN_03483	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MEFHIKGN_03485	3.73e-203	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
MEFHIKGN_03486	3.55e-151	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
MEFHIKGN_03490	9.88e-111	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MEFHIKGN_03491	3.93e-178	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
MEFHIKGN_03492	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MEFHIKGN_03493	0.0	yqbA	-	-	S	-	-	-	portal protein
MEFHIKGN_03494	5.47e-174	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
MEFHIKGN_03495	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
MEFHIKGN_03496	3.16e-80	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MEFHIKGN_03497	1.05e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
MEFHIKGN_03498	1.13e-112	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MEFHIKGN_03499	6.78e-100	xkdJ	-	-	-	-	-	-	-
MEFHIKGN_03500	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MEFHIKGN_03501	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
MEFHIKGN_03502	3.21e-99	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MEFHIKGN_03506	1.05e-228	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MEFHIKGN_03507	3.02e-111	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
MEFHIKGN_03508	2.4e-161	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
MEFHIKGN_03509	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MEFHIKGN_03510	5.46e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MEFHIKGN_03511	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MEFHIKGN_03512	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MEFHIKGN_03513	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MEFHIKGN_03514	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MEFHIKGN_03515	8.73e-162	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MEFHIKGN_03516	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
MEFHIKGN_03517	1.74e-166	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MEFHIKGN_03518	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MEFHIKGN_03519	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MEFHIKGN_03520	8.97e-192	ydjC	-	-	S	-	-	-	Abhydrolase domain containing 18
MEFHIKGN_03521	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
MEFHIKGN_03522	5.88e-256	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
MEFHIKGN_03523	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
MEFHIKGN_03524	1.42e-219	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MEFHIKGN_03525	2.65e-146	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
MEFHIKGN_03526	1.04e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEFHIKGN_03527	2.2e-174	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
MEFHIKGN_03528	3.61e-203	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
MEFHIKGN_03529	3.77e-246	-	-	-	S	-	-	-	Ion transport 2 domain protein
MEFHIKGN_03530	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MEFHIKGN_03531	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
MEFHIKGN_03532	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
MEFHIKGN_03533	3.59e-211	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
MEFHIKGN_03535	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
MEFHIKGN_03536	3.45e-200	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MEFHIKGN_03537	2.49e-229	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
MEFHIKGN_03538	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
MEFHIKGN_03539	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MEFHIKGN_03540	1.76e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEFHIKGN_03541	2.79e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
MEFHIKGN_03542	3.07e-283	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MEFHIKGN_03543	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
MEFHIKGN_03544	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MEFHIKGN_03545	7.14e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MEFHIKGN_03546	9.43e-314	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
MEFHIKGN_03547	4.65e-281	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MEFHIKGN_03548	2.78e-163	yebC	-	-	M	-	-	-	Membrane
MEFHIKGN_03550	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
MEFHIKGN_03551	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
MEFHIKGN_03552	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MEFHIKGN_03553	1.28e-275	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MEFHIKGN_03554	2.81e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MEFHIKGN_03555	5.86e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MEFHIKGN_03556	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEFHIKGN_03557	9.46e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEFHIKGN_03558	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEFHIKGN_03559	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MEFHIKGN_03560	1.71e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MEFHIKGN_03561	8.88e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MEFHIKGN_03562	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MEFHIKGN_03563	2.94e-300	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MEFHIKGN_03564	1.29e-94	-	-	-	K	-	-	-	helix_turn_helix ASNC type
MEFHIKGN_03565	4.8e-291	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
MEFHIKGN_03566	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
MEFHIKGN_03567	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
MEFHIKGN_03568	9.58e-244	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
MEFHIKGN_03569	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_03570	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
MEFHIKGN_03571	4.48e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MEFHIKGN_03572	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MEFHIKGN_03573	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEFHIKGN_03574	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
MEFHIKGN_03575	1.22e-250	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
MEFHIKGN_03576	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MEFHIKGN_03577	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEFHIKGN_03578	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEFHIKGN_03579	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MEFHIKGN_03580	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEFHIKGN_03581	1.26e-191	yerO	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_03582	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MEFHIKGN_03583	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MEFHIKGN_03584	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEFHIKGN_03585	0.0	-	-	-	L	-	-	-	Type III restriction enzyme res subunit
MEFHIKGN_03589	1.59e-124	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MEFHIKGN_03591	5.1e-36	-	-	-	-	-	-	-	-
MEFHIKGN_03592	3.39e-98	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MEFHIKGN_03593	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
MEFHIKGN_03595	2.44e-127	-	-	-	L	-	-	-	endonuclease activity
MEFHIKGN_03596	1.23e-14	-	-	-	S	-	-	-	Pfam:DUF1311
MEFHIKGN_03597	1.31e-266	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
MEFHIKGN_03599	2.56e-161	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
MEFHIKGN_03601	3.46e-130	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_03602	1.48e-106	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
MEFHIKGN_03603	2.77e-194	yesF	-	-	GM	-	-	-	NAD(P)H-binding
MEFHIKGN_03604	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
MEFHIKGN_03605	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
MEFHIKGN_03606	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
MEFHIKGN_03607	6.88e-130	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MEFHIKGN_03609	2.56e-132	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
MEFHIKGN_03610	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_03611	1.39e-257	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
MEFHIKGN_03612	8.33e-314	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MEFHIKGN_03613	2.02e-218	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEFHIKGN_03614	5.11e-210	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEFHIKGN_03615	4.63e-253	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
MEFHIKGN_03616	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_03617	9.4e-167	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MEFHIKGN_03618	1.25e-163	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
MEFHIKGN_03619	3.86e-143	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MEFHIKGN_03620	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
MEFHIKGN_03621	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
MEFHIKGN_03622	6.17e-158	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MEFHIKGN_03623	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
MEFHIKGN_03624	0.0	yetA	-	-	-	-	-	-	-
MEFHIKGN_03625	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MEFHIKGN_03626	5.62e-225	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
MEFHIKGN_03627	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEFHIKGN_03628	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MEFHIKGN_03629	1.49e-156	yetF	-	-	S	-	-	-	membrane
MEFHIKGN_03630	4.67e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
MEFHIKGN_03631	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEFHIKGN_03632	1.75e-44	-	-	-	-	-	-	-	-
MEFHIKGN_03633	1.2e-182	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MEFHIKGN_03634	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
MEFHIKGN_03635	1.04e-134	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MEFHIKGN_03636	2.75e-116	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MEFHIKGN_03637	1.2e-263	yetM	-	-	CH	-	-	-	FAD binding domain
MEFHIKGN_03638	6.1e-255	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
MEFHIKGN_03639	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MEFHIKGN_03640	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MEFHIKGN_03641	5.07e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
MEFHIKGN_03642	1.2e-237	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
MEFHIKGN_03643	3.28e-230	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MEFHIKGN_03644	1.16e-284	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
MEFHIKGN_03645	2.34e-243	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MEFHIKGN_03646	6.21e-268	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_03647	2.13e-167	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MEFHIKGN_03648	3.41e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
MEFHIKGN_03649	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MEFHIKGN_03650	1.47e-160	yfmS	-	-	NT	-	-	-	chemotaxis protein
MEFHIKGN_03651	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MEFHIKGN_03652	1.31e-98	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
MEFHIKGN_03653	3.54e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
MEFHIKGN_03654	4.88e-263	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
MEFHIKGN_03655	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MEFHIKGN_03656	2.42e-262	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
MEFHIKGN_03657	2.55e-105	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
MEFHIKGN_03658	2.84e-240	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
MEFHIKGN_03659	3.46e-268	-	-	-	G	-	-	-	Major Facilitator Superfamily
MEFHIKGN_03660	0.0	pkn1	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
MEFHIKGN_03661	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MEFHIKGN_03662	5.76e-221	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEFHIKGN_03663	2.73e-219	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEFHIKGN_03664	1.6e-218	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MEFHIKGN_03665	3.01e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
MEFHIKGN_03666	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
MEFHIKGN_03667	2.45e-307	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MEFHIKGN_03668	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MEFHIKGN_03669	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MEFHIKGN_03670	1.88e-152	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MEFHIKGN_03671	1.14e-229	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MEFHIKGN_03672	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MEFHIKGN_03673	3.43e-192	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MEFHIKGN_03674	4.79e-276	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MEFHIKGN_03675	2.97e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MEFHIKGN_03676	5.68e-156	yflK	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_03677	1.1e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
MEFHIKGN_03678	2.82e-26	yflI	-	-	-	-	-	-	-
MEFHIKGN_03679	2.1e-65	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MEFHIKGN_03680	6.62e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MEFHIKGN_03681	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MEFHIKGN_03682	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MEFHIKGN_03683	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
MEFHIKGN_03684	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
MEFHIKGN_03685	5.09e-33	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
MEFHIKGN_03686	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MEFHIKGN_03687	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
MEFHIKGN_03688	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
MEFHIKGN_03689	6.16e-160	frp	-	-	C	-	-	-	nitroreductase
MEFHIKGN_03690	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MEFHIKGN_03691	5.48e-114	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MEFHIKGN_03692	6.21e-266	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_03693	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
MEFHIKGN_03694	2.14e-110	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MEFHIKGN_03695	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
MEFHIKGN_03696	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MEFHIKGN_03697	1.64e-12	-	-	-	-	-	-	-	-
MEFHIKGN_03698	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_03699	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
MEFHIKGN_03700	2.14e-188	yfkD	-	-	S	-	-	-	YfkD-like protein
MEFHIKGN_03701	4.97e-188	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
MEFHIKGN_03702	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
MEFHIKGN_03703	3.26e-36	yfjT	-	-	-	-	-	-	-
MEFHIKGN_03704	5.95e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
MEFHIKGN_03705	7.33e-189	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MEFHIKGN_03706	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
MEFHIKGN_03707	2.76e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MEFHIKGN_03708	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEFHIKGN_03709	4.32e-59	-	-	-	S	-	-	-	YfzA-like protein
MEFHIKGN_03710	3.33e-241	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEFHIKGN_03711	6.46e-109	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
MEFHIKGN_03713	5.55e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MEFHIKGN_03714	3.74e-242	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MEFHIKGN_03715	5.7e-263	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEFHIKGN_03716	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MEFHIKGN_03717	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
MEFHIKGN_03718	2.75e-34	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
MEFHIKGN_03719	1.38e-72	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
MEFHIKGN_03720	5.95e-113	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
MEFHIKGN_03721	4.33e-161	yfjC	-	-	-	-	-	-	-
MEFHIKGN_03722	1.62e-239	yfjB	-	-	-	-	-	-	-
MEFHIKGN_03723	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
MEFHIKGN_03724	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MEFHIKGN_03725	2.49e-180	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MEFHIKGN_03726	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MEFHIKGN_03727	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MEFHIKGN_03728	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MEFHIKGN_03729	3.34e-83	yfiD3	-	-	S	-	-	-	DoxX
MEFHIKGN_03730	4.21e-208	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
MEFHIKGN_03732	8.07e-271	baeS	-	-	T	-	-	-	Histidine kinase
MEFHIKGN_03733	6.07e-146	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
MEFHIKGN_03734	1.94e-217	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_03735	5.32e-267	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MEFHIKGN_03736	1.82e-257	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MEFHIKGN_03737	1.89e-128	padR	-	-	K	-	-	-	transcriptional
MEFHIKGN_03738	1.3e-126	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MEFHIKGN_03739	2.68e-252	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MEFHIKGN_03740	3.3e-138	yfiR	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_03741	1.91e-266	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
MEFHIKGN_03742	2.7e-126	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
MEFHIKGN_03743	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
MEFHIKGN_03744	1.27e-104	yfiV	-	-	K	-	-	-	transcriptional
MEFHIKGN_03745	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEFHIKGN_03746	1.1e-230	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MEFHIKGN_03747	8.91e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEFHIKGN_03748	7.36e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEFHIKGN_03749	7.61e-215	yfhB	-	-	S	-	-	-	PhzF family
MEFHIKGN_03750	2.36e-137	yfhC	-	-	C	-	-	-	nitroreductase
MEFHIKGN_03751	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
MEFHIKGN_03753	3.79e-220	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
MEFHIKGN_03754	3.25e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MEFHIKGN_03755	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
MEFHIKGN_03757	2.45e-268	yfhI	-	-	EGP	-	-	-	-transporter
MEFHIKGN_03758	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
MEFHIKGN_03759	2.57e-59	yfhJ	-	-	S	-	-	-	WVELL protein
MEFHIKGN_03760	1.91e-114	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
MEFHIKGN_03761	5.4e-67	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
MEFHIKGN_03762	3.37e-219	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
MEFHIKGN_03763	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MEFHIKGN_03764	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MEFHIKGN_03765	7.22e-237	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
MEFHIKGN_03766	7.9e-269	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
MEFHIKGN_03767	1.73e-48	yfhS	-	-	-	-	-	-	-
MEFHIKGN_03768	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEFHIKGN_03769	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
MEFHIKGN_03770	2.01e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
MEFHIKGN_03771	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MEFHIKGN_03772	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
MEFHIKGN_03773	1.87e-238	ygaE	-	-	S	-	-	-	Membrane
MEFHIKGN_03774	3.4e-314	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MEFHIKGN_03775	8.36e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
MEFHIKGN_03776	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MEFHIKGN_03777	5.46e-74	ygzB	-	-	S	-	-	-	UPF0295 protein
MEFHIKGN_03778	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
MEFHIKGN_03779	1.45e-314	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
MEFHIKGN_03780	2.77e-270	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MEFHIKGN_03781	3.94e-170	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_03782	6.05e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MEFHIKGN_03783	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MEFHIKGN_03784	3.63e-120	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEFHIKGN_03785	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEFHIKGN_03786	1.84e-235	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
MEFHIKGN_03787	5.69e-194	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
MEFHIKGN_03790	7.32e-42	yxeE	-	-	-	-	-	-	-
MEFHIKGN_03791	2.66e-28	yxeD	-	-	-	-	-	-	-
MEFHIKGN_03792	6.79e-91	-	-	-	-	-	-	-	-
MEFHIKGN_03793	1.23e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MEFHIKGN_03794	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
MEFHIKGN_03795	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MEFHIKGN_03796	9.39e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MEFHIKGN_03797	1.63e-232	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_03798	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEFHIKGN_03799	6.95e-205	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MEFHIKGN_03800	1.54e-186	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MEFHIKGN_03801	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
MEFHIKGN_03802	6.3e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MEFHIKGN_03803	4.01e-296	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
MEFHIKGN_03804	4.99e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MEFHIKGN_03805	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MEFHIKGN_03806	6.81e-225	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MEFHIKGN_03807	9.89e-200	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MEFHIKGN_03808	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MEFHIKGN_03809	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MEFHIKGN_03810	1.43e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MEFHIKGN_03812	2.39e-61	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
MEFHIKGN_03813	5.91e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MEFHIKGN_03814	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
MEFHIKGN_03816	1.45e-193	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MEFHIKGN_03817	6.07e-274	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MEFHIKGN_03818	3.42e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MEFHIKGN_03820	5.51e-30	yxaI	-	-	S	-	-	-	membrane protein domain
MEFHIKGN_03821	5.06e-114	yxaL	-	-	S	-	-	-	PQQ-like domain
MEFHIKGN_03822	3.24e-82	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
MEFHIKGN_03823	4.03e-99	yxaI	-	-	S	-	-	-	membrane protein domain
MEFHIKGN_03824	1.08e-285	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MEFHIKGN_03825	3e-250	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
MEFHIKGN_03826	3.91e-130	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MEFHIKGN_03827	5.01e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MEFHIKGN_03828	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MEFHIKGN_03829	6.51e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
MEFHIKGN_03830	2.19e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
MEFHIKGN_03831	1.21e-243	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
MEFHIKGN_03832	4.71e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MEFHIKGN_03833	1.27e-163	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
MEFHIKGN_03834	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MEFHIKGN_03835	1.18e-294	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MEFHIKGN_03836	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MEFHIKGN_03837	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
MEFHIKGN_03838	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
MEFHIKGN_03839	1.11e-237	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
MEFHIKGN_03840	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MEFHIKGN_03841	7.55e-44	-	2.7.1.199	-	G	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
MEFHIKGN_03842	5.21e-164	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
MEFHIKGN_03843	1.44e-24	-	-	-	-	-	-	-	-
MEFHIKGN_03844	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
MEFHIKGN_03845	2.37e-94	-	-	-	J	-	-	-	COG0617 tRNA nucleotidyltransferase poly(A) polymerase
MEFHIKGN_03846	3.08e-261	-	-	-	S	-	-	-	Protein of unknown function DUF262
MEFHIKGN_03847	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
MEFHIKGN_03848	2.99e-127	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
MEFHIKGN_03849	4.45e-156	-	-	-	L	-	-	-	Recombinase
MEFHIKGN_03850	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MEFHIKGN_03852	5.95e-92	-	-	-	-	-	-	-	-
MEFHIKGN_03853	1.81e-297	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MEFHIKGN_03855	5.5e-42	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MEFHIKGN_03856	1.4e-262	yycP	-	-	-	-	-	-	-
MEFHIKGN_03857	1.96e-168	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MEFHIKGN_03858	8.71e-110	yycN	-	-	K	-	-	-	Acetyltransferase
MEFHIKGN_03859	1.23e-238	-	-	-	S	-	-	-	aspartate phosphatase
MEFHIKGN_03861	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MEFHIKGN_03862	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MEFHIKGN_03863	6.41e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
MEFHIKGN_03864	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MEFHIKGN_03865	9.16e-215	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MEFHIKGN_03866	6.75e-122	-	-	-	K	ko:K02483	-	ko00000,ko02022	PFAM response regulator receiver
MEFHIKGN_03867	1.88e-97	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MEFHIKGN_03868	1.4e-43	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MEFHIKGN_03869	4.48e-277	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MEFHIKGN_03870	3.29e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MEFHIKGN_03871	1.2e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_03872	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_03873	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEFHIKGN_03874	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEFHIKGN_03879	1.29e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MEFHIKGN_03880	4.68e-99	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEFHIKGN_03881	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MEFHIKGN_03882	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MEFHIKGN_03884	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
MEFHIKGN_03885	9.87e-282	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
MEFHIKGN_03886	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEFHIKGN_03887	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MEFHIKGN_03888	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MEFHIKGN_03889	1.5e-204	yybS	-	-	S	-	-	-	membrane
MEFHIKGN_03891	6.83e-109	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
MEFHIKGN_03892	1.3e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_03893	6.65e-208	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
MEFHIKGN_03894	3.73e-89	-	-	-	-	-	-	-	-
MEFHIKGN_03896	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_03897	3.59e-141	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
MEFHIKGN_03898	7.14e-184	-	-	-	-	-	-	-	-
MEFHIKGN_03899	1.38e-84	-	-	-	S	-	-	-	SnoaL-like domain
MEFHIKGN_03900	1.98e-162	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
MEFHIKGN_03901	2.04e-275	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_03902	4.56e-211	yybE	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_03903	4.58e-103	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MEFHIKGN_03904	5.79e-96	yybC	-	-	-	-	-	-	-
MEFHIKGN_03905	2.16e-164	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MEFHIKGN_03906	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
MEFHIKGN_03907	2.85e-93	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MEFHIKGN_03908	1.74e-124	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
MEFHIKGN_03909	2.72e-119	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
MEFHIKGN_03910	1.5e-85	-	-	-	S	-	-	-	YjbR
MEFHIKGN_03911	8.62e-137	yyaP	-	-	H	-	-	-	RibD C-terminal domain
MEFHIKGN_03912	8.09e-314	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
MEFHIKGN_03913	9.19e-36	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MEFHIKGN_03915	2.16e-07	-	-	-	S	-	-	-	Putative amidase domain
MEFHIKGN_03916	1.34e-88	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MEFHIKGN_03917	1.34e-205	-	-	-	EG	-	-	-	EamA-like transporter family
MEFHIKGN_03918	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MEFHIKGN_03919	2.1e-215	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MEFHIKGN_03920	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
MEFHIKGN_03921	3.81e-129	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
MEFHIKGN_03922	2.32e-86	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEFHIKGN_03923	6.85e-227	ccpB	-	-	K	-	-	-	Transcriptional regulator
MEFHIKGN_03924	4.68e-184	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MEFHIKGN_03925	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MEFHIKGN_03926	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MEFHIKGN_03927	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MEFHIKGN_03928	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MEFHIKGN_03929	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MEFHIKGN_03930	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_03931	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
MEFHIKGN_03932	1.3e-144	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
MEFHIKGN_03933	1.32e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MEFHIKGN_03934	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
MEFHIKGN_03935	2.18e-96	-	-	-	S	-	-	-	Bacterial PH domain
MEFHIKGN_03936	2.58e-192	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MEFHIKGN_03937	2.9e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MEFHIKGN_03938	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MEFHIKGN_03939	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MEFHIKGN_03940	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
MEFHIKGN_03941	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEFHIKGN_03942	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MEFHIKGN_03943	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MEFHIKGN_03944	1.71e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEFHIKGN_03945	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MEFHIKGN_03946	4.54e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MEFHIKGN_03947	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
MEFHIKGN_03948	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEFHIKGN_03949	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEFHIKGN_03950	1.23e-180	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
MEFHIKGN_03951	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
MEFHIKGN_03952	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
MEFHIKGN_03953	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MEFHIKGN_03954	9.05e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MEFHIKGN_03955	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
MEFHIKGN_03956	2.06e-184	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
MEFHIKGN_03957	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MEFHIKGN_03958	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MEFHIKGN_03959	1.51e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MEFHIKGN_03960	3.23e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEFHIKGN_03961	1.1e-196	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEFHIKGN_03962	7.5e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEFHIKGN_03963	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MEFHIKGN_03964	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEFHIKGN_03965	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MEFHIKGN_03966	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MEFHIKGN_03967	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MEFHIKGN_03968	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MEFHIKGN_03969	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MEFHIKGN_03970	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MEFHIKGN_03971	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MEFHIKGN_03972	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MEFHIKGN_03973	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MEFHIKGN_03974	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MEFHIKGN_03975	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MEFHIKGN_03976	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MEFHIKGN_03977	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MEFHIKGN_03978	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEFHIKGN_03979	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MEFHIKGN_03980	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MEFHIKGN_03981	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MEFHIKGN_03982	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MEFHIKGN_03983	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MEFHIKGN_03984	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MEFHIKGN_03985	5.9e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MEFHIKGN_03986	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MEFHIKGN_03987	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MEFHIKGN_03988	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MEFHIKGN_03989	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MEFHIKGN_03990	7.98e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MEFHIKGN_03991	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MEFHIKGN_03992	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MEFHIKGN_03993	1.5e-229	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
MEFHIKGN_03994	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MEFHIKGN_03995	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MEFHIKGN_03996	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MEFHIKGN_03997	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MEFHIKGN_03998	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
MEFHIKGN_03999	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEFHIKGN_04000	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEFHIKGN_04001	3.16e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MEFHIKGN_04002	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MEFHIKGN_04003	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MEFHIKGN_04004	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MEFHIKGN_04005	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MEFHIKGN_04006	1.19e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MEFHIKGN_04007	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MEFHIKGN_04008	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MEFHIKGN_04009	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
MEFHIKGN_04010	1.43e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEFHIKGN_04011	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MEFHIKGN_04012	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MEFHIKGN_04013	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
MEFHIKGN_04014	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEFHIKGN_04015	6.35e-113	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MEFHIKGN_04016	7.42e-162	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MEFHIKGN_04017	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
MEFHIKGN_04018	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MEFHIKGN_04019	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MEFHIKGN_04020	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MEFHIKGN_04021	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MEFHIKGN_04022	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
MEFHIKGN_04023	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MEFHIKGN_04024	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MEFHIKGN_04025	1.59e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEFHIKGN_04026	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
MEFHIKGN_04027	2.64e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MEFHIKGN_04028	3.8e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MEFHIKGN_04029	3.32e-205	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MEFHIKGN_04030	2.27e-216	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
MEFHIKGN_04031	5.98e-137	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
MEFHIKGN_04032	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MEFHIKGN_04033	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MEFHIKGN_04034	1.7e-204	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
MEFHIKGN_04035	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MEFHIKGN_04036	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MEFHIKGN_04037	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MEFHIKGN_04038	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
MEFHIKGN_04039	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MEFHIKGN_04040	6.92e-236	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MEFHIKGN_04041	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MEFHIKGN_04042	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
MEFHIKGN_04045	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MEFHIKGN_04046	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MEFHIKGN_04047	2.58e-138	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
MEFHIKGN_04048	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
MEFHIKGN_04049	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MEFHIKGN_04050	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MEFHIKGN_04051	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MEFHIKGN_04052	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
MEFHIKGN_04053	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MEFHIKGN_04054	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
MEFHIKGN_04055	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MEFHIKGN_04056	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MEFHIKGN_04057	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEFHIKGN_04058	2.58e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MEFHIKGN_04059	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MEFHIKGN_04060	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
MEFHIKGN_04061	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MEFHIKGN_04062	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MEFHIKGN_04063	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
MEFHIKGN_04064	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_04065	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
MEFHIKGN_04066	2.05e-198	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MEFHIKGN_04067	2.03e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MEFHIKGN_04068	1.67e-277	yabE	-	-	T	-	-	-	protein conserved in bacteria
MEFHIKGN_04069	5.9e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
MEFHIKGN_04070	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MEFHIKGN_04071	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
MEFHIKGN_04072	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MEFHIKGN_04073	1.41e-63	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
MEFHIKGN_04074	2.81e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
MEFHIKGN_04075	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MEFHIKGN_04076	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
MEFHIKGN_04077	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MEFHIKGN_04078	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
MEFHIKGN_04079	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
MEFHIKGN_04080	1.63e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MEFHIKGN_04081	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
MEFHIKGN_04082	6.87e-258	yaaN	-	-	P	-	-	-	Belongs to the TelA family
MEFHIKGN_04083	2.7e-132	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MEFHIKGN_04084	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
MEFHIKGN_04085	2.14e-232	yaaC	-	-	S	-	-	-	YaaC-like Protein
MEFHIKGN_04086	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MEFHIKGN_04087	2.16e-315	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MEFHIKGN_04088	5.26e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MEFHIKGN_04089	1.66e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MEFHIKGN_04090	6.6e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MEFHIKGN_04092	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
MEFHIKGN_04093	9.51e-148	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
MEFHIKGN_04094	3.65e-276	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
MEFHIKGN_04095	5.64e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
MEFHIKGN_04096	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MEFHIKGN_04097	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEFHIKGN_04098	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MEFHIKGN_04099	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MEFHIKGN_04100	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MEFHIKGN_04101	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
MEFHIKGN_04102	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group