ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
AFOFKEHG_00011 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
AFOFKEHG_00012 3.88e-37 - - - - - - - -
AFOFKEHG_00013 6.95e-173 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
AFOFKEHG_00014 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AFOFKEHG_00015 0.0 ygaK - - C - - - Berberine and berberine like
AFOFKEHG_00017 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
AFOFKEHG_00018 4.15e-185 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
AFOFKEHG_00019 8.45e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
AFOFKEHG_00020 4.82e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
AFOFKEHG_00021 2.2e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
AFOFKEHG_00023 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AFOFKEHG_00024 5.19e-98 ygaO - - - - - - -
AFOFKEHG_00025 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_00027 6.43e-146 yhzB - - S - - - B3/4 domain
AFOFKEHG_00028 2.95e-284 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AFOFKEHG_00029 1.6e-224 yhbB - - S - - - Putative amidase domain
AFOFKEHG_00030 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AFOFKEHG_00031 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
AFOFKEHG_00032 1.32e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
AFOFKEHG_00033 2.12e-105 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
AFOFKEHG_00034 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
AFOFKEHG_00035 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
AFOFKEHG_00036 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
AFOFKEHG_00037 3.8e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
AFOFKEHG_00038 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
AFOFKEHG_00039 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
AFOFKEHG_00040 3.95e-59 yhcC - - - - - - -
AFOFKEHG_00041 1.67e-68 - - - - - - - -
AFOFKEHG_00042 4.78e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_00043 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_00044 7.55e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_00045 3.45e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
AFOFKEHG_00046 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
AFOFKEHG_00047 2.23e-194 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
AFOFKEHG_00048 1.67e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
AFOFKEHG_00049 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFOFKEHG_00050 1.96e-71 yhcM - - - - - - -
AFOFKEHG_00051 2.69e-111 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
AFOFKEHG_00052 6.57e-226 yhcP - - - - - - -
AFOFKEHG_00053 2.29e-144 yhcQ - - M - - - Spore coat protein
AFOFKEHG_00054 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
AFOFKEHG_00055 1.25e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
AFOFKEHG_00056 6.51e-216 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
AFOFKEHG_00057 2.47e-88 yhcU - - S - - - Family of unknown function (DUF5365)
AFOFKEHG_00058 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
AFOFKEHG_00059 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
AFOFKEHG_00060 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
AFOFKEHG_00061 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AFOFKEHG_00062 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AFOFKEHG_00063 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
AFOFKEHG_00064 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AFOFKEHG_00065 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AFOFKEHG_00066 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
AFOFKEHG_00067 5.38e-272 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_00068 4.47e-143 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFOFKEHG_00069 1.63e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
AFOFKEHG_00070 1.65e-51 yhdB - - S - - - YhdB-like protein
AFOFKEHG_00071 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
AFOFKEHG_00072 1.39e-274 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
AFOFKEHG_00073 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
AFOFKEHG_00074 1.76e-305 ygxB - - M - - - Conserved TM helix
AFOFKEHG_00075 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
AFOFKEHG_00076 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
AFOFKEHG_00077 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
AFOFKEHG_00078 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_00079 1.06e-260 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
AFOFKEHG_00080 5.51e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFOFKEHG_00081 3.58e-316 yhdG - - E ko:K03294 - ko00000 amino acid
AFOFKEHG_00082 5e-309 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
AFOFKEHG_00083 4.26e-130 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFOFKEHG_00084 2.91e-99 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFOFKEHG_00085 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
AFOFKEHG_00086 3.54e-257 yhdL - - S - - - Sigma factor regulator N-terminal
AFOFKEHG_00087 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
AFOFKEHG_00088 1.93e-243 yhdN - - C - - - Aldo keto reductase
AFOFKEHG_00089 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
AFOFKEHG_00090 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
AFOFKEHG_00091 1.42e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
AFOFKEHG_00092 8.1e-281 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
AFOFKEHG_00093 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
AFOFKEHG_00094 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AFOFKEHG_00095 1.67e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AFOFKEHG_00096 2.22e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
AFOFKEHG_00097 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
AFOFKEHG_00098 4.14e-240 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
AFOFKEHG_00099 2.93e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
AFOFKEHG_00100 5.7e-200 nodB1 - - G - - - deacetylase
AFOFKEHG_00101 2.23e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
AFOFKEHG_00102 3.94e-307 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
AFOFKEHG_00103 3.85e-109 nhaX - - T - - - Belongs to the universal stress protein A family
AFOFKEHG_00104 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
AFOFKEHG_00105 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
AFOFKEHG_00106 3.31e-143 yheG - - GM - - - NAD(P)H-binding
AFOFKEHG_00107 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
AFOFKEHG_00108 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
AFOFKEHG_00109 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
AFOFKEHG_00110 2.77e-275 yheC - - HJ - - - YheC/D like ATP-grasp
AFOFKEHG_00111 4.16e-259 yheB - - S - - - Belongs to the UPF0754 family
AFOFKEHG_00112 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
AFOFKEHG_00113 1.29e-261 yhaZ - - L - - - DNA alkylation repair enzyme
AFOFKEHG_00114 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
AFOFKEHG_00115 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
AFOFKEHG_00116 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
AFOFKEHG_00117 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
AFOFKEHG_00119 1.26e-169 yhaR - - I - - - enoyl-CoA hydratase
AFOFKEHG_00120 2.29e-36 - - - S - - - YhzD-like protein
AFOFKEHG_00121 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_00122 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
AFOFKEHG_00123 9.85e-303 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
AFOFKEHG_00124 0.0 yhaN - - L - - - AAA domain
AFOFKEHG_00125 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
AFOFKEHG_00126 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
AFOFKEHG_00127 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AFOFKEHG_00128 1.4e-116 yhaK - - S - - - Putative zincin peptidase
AFOFKEHG_00129 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
AFOFKEHG_00130 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
AFOFKEHG_00131 1.74e-54 yhaH - - S - - - YtxH-like protein
AFOFKEHG_00132 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
AFOFKEHG_00133 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AFOFKEHG_00134 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
AFOFKEHG_00135 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
AFOFKEHG_00136 3.11e-272 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
AFOFKEHG_00137 2.04e-161 ecsC - - S - - - EcsC protein family
AFOFKEHG_00138 2.19e-291 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
AFOFKEHG_00139 6.63e-313 yhfA - - C - - - membrane
AFOFKEHG_00140 2.31e-24 - - - C - - - Rubrerythrin
AFOFKEHG_00141 5.35e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
AFOFKEHG_00142 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
AFOFKEHG_00143 7.78e-261 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AFOFKEHG_00144 2.06e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
AFOFKEHG_00145 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AFOFKEHG_00146 3.49e-133 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_00147 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
AFOFKEHG_00148 3.43e-234 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AFOFKEHG_00149 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
AFOFKEHG_00150 2.68e-253 yhfE - - G - - - peptidase M42
AFOFKEHG_00151 6.22e-93 - - - S - - - ASCH
AFOFKEHG_00152 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFOFKEHG_00153 3.43e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
AFOFKEHG_00154 3.34e-244 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
AFOFKEHG_00155 2.48e-142 yhfK - - GM - - - NmrA-like family
AFOFKEHG_00156 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
AFOFKEHG_00157 2.78e-85 yhfM - - - - - - -
AFOFKEHG_00158 3.76e-305 yhfN - - O - - - Peptidase M48
AFOFKEHG_00159 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
AFOFKEHG_00160 2.44e-99 - - - K - - - acetyltransferase
AFOFKEHG_00161 3.98e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
AFOFKEHG_00162 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
AFOFKEHG_00163 2.27e-139 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
AFOFKEHG_00164 1.73e-249 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
AFOFKEHG_00165 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
AFOFKEHG_00166 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
AFOFKEHG_00167 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
AFOFKEHG_00168 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
AFOFKEHG_00169 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFOFKEHG_00170 9.84e-45 yhzC - - S - - - IDEAL
AFOFKEHG_00171 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
AFOFKEHG_00172 1.03e-199 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
AFOFKEHG_00173 5e-57 yhjA - - S - - - Excalibur calcium-binding domain
AFOFKEHG_00174 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFOFKEHG_00175 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
AFOFKEHG_00176 2.57e-78 yhjD - - - - - - -
AFOFKEHG_00177 1.98e-140 yhjE - - S - - - SNARE associated Golgi protein
AFOFKEHG_00178 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
AFOFKEHG_00179 0.0 yhjG - - CH - - - FAD binding domain
AFOFKEHG_00180 3.29e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
AFOFKEHG_00181 2.46e-270 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
AFOFKEHG_00182 7.71e-255 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
AFOFKEHG_00183 6.2e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
AFOFKEHG_00184 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
AFOFKEHG_00185 1.77e-238 yhjM - - K - - - Transcriptional regulator
AFOFKEHG_00186 2.5e-259 yhjN - - S ko:K07120 - ko00000 membrane
AFOFKEHG_00187 1.04e-271 - - - EGP - - - Transmembrane secretion effector
AFOFKEHG_00188 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
AFOFKEHG_00189 3.54e-77 yhjQ - - C - - - COG1145 Ferredoxin
AFOFKEHG_00190 9.3e-102 yhjR - - S - - - Rubrerythrin
AFOFKEHG_00191 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
AFOFKEHG_00192 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
AFOFKEHG_00193 1.2e-281 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AFOFKEHG_00194 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
AFOFKEHG_00195 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
AFOFKEHG_00196 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
AFOFKEHG_00197 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
AFOFKEHG_00198 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
AFOFKEHG_00199 2.88e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
AFOFKEHG_00200 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
AFOFKEHG_00201 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
AFOFKEHG_00202 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
AFOFKEHG_00203 8.94e-221 cotH - - M ko:K06330 - ko00000 Spore Coat
AFOFKEHG_00204 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
AFOFKEHG_00205 1.02e-74 yisL - - S - - - UPF0344 protein
AFOFKEHG_00206 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
AFOFKEHG_00207 7.42e-132 yisN - - S - - - Protein of unknown function (DUF2777)
AFOFKEHG_00208 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
AFOFKEHG_00209 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
AFOFKEHG_00210 1.54e-189 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
AFOFKEHG_00211 1.01e-310 yisQ - - V - - - Mate efflux family protein
AFOFKEHG_00212 8.16e-207 yisR - - K - - - Transcriptional regulator
AFOFKEHG_00213 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
AFOFKEHG_00214 1e-246 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
AFOFKEHG_00215 9.94e-120 yisT - - S - - - DinB family
AFOFKEHG_00216 2.08e-128 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
AFOFKEHG_00217 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFOFKEHG_00218 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
AFOFKEHG_00219 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
AFOFKEHG_00220 2.35e-144 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
AFOFKEHG_00221 1.37e-295 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
AFOFKEHG_00222 1.11e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
AFOFKEHG_00223 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
AFOFKEHG_00224 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
AFOFKEHG_00225 6.62e-140 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
AFOFKEHG_00226 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
AFOFKEHG_00227 4.1e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_00228 1.62e-179 yitH - - K - - - Acetyltransferase (GNAT) domain
AFOFKEHG_00229 5.09e-92 - - - S - - - Acetyltransferase (GNAT) domain
AFOFKEHG_00230 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
AFOFKEHG_00231 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
AFOFKEHG_00232 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
AFOFKEHG_00233 4.16e-122 - - - - - - - -
AFOFKEHG_00234 1.42e-218 - - - - - - - -
AFOFKEHG_00235 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
AFOFKEHG_00236 1.2e-76 - - - K - - - Transcriptional regulator PadR-like family
AFOFKEHG_00237 6.11e-120 - - - - - - - -
AFOFKEHG_00238 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
AFOFKEHG_00239 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
AFOFKEHG_00240 9.13e-202 yitS - - S - - - protein conserved in bacteria
AFOFKEHG_00241 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
AFOFKEHG_00242 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
AFOFKEHG_00243 4.11e-25 - - - S - - - Protein of unknown function (DUF3813)
AFOFKEHG_00244 1.92e-08 - - - - - - - -
AFOFKEHG_00245 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
AFOFKEHG_00246 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
AFOFKEHG_00247 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
AFOFKEHG_00248 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
AFOFKEHG_00249 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
AFOFKEHG_00250 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
AFOFKEHG_00251 7.41e-255 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AFOFKEHG_00252 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AFOFKEHG_00253 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
AFOFKEHG_00254 1.69e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
AFOFKEHG_00255 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
AFOFKEHG_00256 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
AFOFKEHG_00257 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AFOFKEHG_00258 2.51e-39 yjzC - - S - - - YjzC-like protein
AFOFKEHG_00259 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
AFOFKEHG_00260 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
AFOFKEHG_00261 5.41e-134 yjaV - - - - - - -
AFOFKEHG_00262 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
AFOFKEHG_00263 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
AFOFKEHG_00264 2.67e-38 yjzB - - - - - - -
AFOFKEHG_00265 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AFOFKEHG_00266 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AFOFKEHG_00267 9.48e-193 yjaZ - - O - - - Zn-dependent protease
AFOFKEHG_00268 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
AFOFKEHG_00269 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
AFOFKEHG_00270 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
AFOFKEHG_00271 3.73e-213 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFOFKEHG_00272 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFOFKEHG_00273 7.51e-189 yjbA - - S - - - Belongs to the UPF0736 family
AFOFKEHG_00274 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
AFOFKEHG_00275 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
AFOFKEHG_00276 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFOFKEHG_00277 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFOFKEHG_00278 1.37e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
AFOFKEHG_00279 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
AFOFKEHG_00280 3.98e-248 yjbB - - EGP - - - Major Facilitator Superfamily
AFOFKEHG_00281 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFOFKEHG_00282 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AFOFKEHG_00283 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
AFOFKEHG_00284 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
AFOFKEHG_00285 8.84e-282 coiA - - S ko:K06198 - ko00000 Competence protein
AFOFKEHG_00286 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
AFOFKEHG_00287 2.68e-28 - - - - - - - -
AFOFKEHG_00288 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
AFOFKEHG_00289 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
AFOFKEHG_00290 3.42e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
AFOFKEHG_00291 5.15e-130 yjbK - - S - - - protein conserved in bacteria
AFOFKEHG_00292 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
AFOFKEHG_00293 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
AFOFKEHG_00294 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AFOFKEHG_00295 2.58e-203 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
AFOFKEHG_00296 1.15e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
AFOFKEHG_00297 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AFOFKEHG_00298 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AFOFKEHG_00299 4.01e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
AFOFKEHG_00300 1.09e-275 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
AFOFKEHG_00301 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
AFOFKEHG_00302 2.76e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
AFOFKEHG_00303 2.94e-236 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
AFOFKEHG_00304 6.89e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
AFOFKEHG_00305 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
AFOFKEHG_00306 2.56e-104 yjbX - - S - - - Spore coat protein
AFOFKEHG_00307 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
AFOFKEHG_00308 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
AFOFKEHG_00309 2.87e-94 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
AFOFKEHG_00310 8.7e-34 cotW - - - ko:K06341 - ko00000 -
AFOFKEHG_00311 1.18e-71 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
AFOFKEHG_00312 5.03e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
AFOFKEHG_00315 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
AFOFKEHG_00316 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
AFOFKEHG_00317 6.31e-51 - - - - - - - -
AFOFKEHG_00318 2.22e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFOFKEHG_00319 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
AFOFKEHG_00320 7.77e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
AFOFKEHG_00321 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
AFOFKEHG_00322 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
AFOFKEHG_00323 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
AFOFKEHG_00324 1.05e-273 yjcL - - S - - - Protein of unknown function (DUF819)
AFOFKEHG_00327 1.33e-50 - - - - - - - -
AFOFKEHG_00329 2.35e-295 - - - M - - - nucleic acid phosphodiester bond hydrolysis
AFOFKEHG_00332 1.42e-09 - - - S - - - YolD-like protein
AFOFKEHG_00333 1.92e-47 - - - - - - - -
AFOFKEHG_00334 3.94e-26 - - - - - - - -
AFOFKEHG_00335 2.49e-07 - - - - - - - -
AFOFKEHG_00336 3.8e-63 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
AFOFKEHG_00337 3.42e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
AFOFKEHG_00338 0.000759 - - - - - - - -
AFOFKEHG_00339 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
AFOFKEHG_00340 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
AFOFKEHG_00341 6.2e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
AFOFKEHG_00342 4.79e-78 yjdF3 - - S - - - Protein of unknown function (DUF2992)
AFOFKEHG_00343 1.36e-121 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
AFOFKEHG_00345 1.01e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AFOFKEHG_00346 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
AFOFKEHG_00347 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
AFOFKEHG_00348 5.31e-224 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
AFOFKEHG_00350 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
AFOFKEHG_00351 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
AFOFKEHG_00352 1.95e-30 yjfB - - S - - - Putative motility protein
AFOFKEHG_00353 3.24e-219 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
AFOFKEHG_00354 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
AFOFKEHG_00355 1.22e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
AFOFKEHG_00356 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
AFOFKEHG_00357 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
AFOFKEHG_00359 1.91e-149 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
AFOFKEHG_00361 1.48e-289 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
AFOFKEHG_00362 8.74e-280 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
AFOFKEHG_00363 1.11e-41 - - - - - - - -
AFOFKEHG_00364 8.69e-189 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
AFOFKEHG_00365 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
AFOFKEHG_00366 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
AFOFKEHG_00367 1.09e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
AFOFKEHG_00368 8.91e-121 yjlB - - S - - - Cupin domain
AFOFKEHG_00369 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
AFOFKEHG_00370 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
AFOFKEHG_00371 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
AFOFKEHG_00372 1.02e-312 - - - G ko:K03292 - ko00000 symporter YjmB
AFOFKEHG_00373 6.68e-238 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
AFOFKEHG_00374 1.21e-241 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
AFOFKEHG_00375 2.27e-272 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
AFOFKEHG_00376 5.47e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
AFOFKEHG_00377 4.58e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
AFOFKEHG_00378 8.11e-237 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
AFOFKEHG_00379 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
AFOFKEHG_00380 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
AFOFKEHG_00381 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
AFOFKEHG_00382 2.71e-103 yjoA - - S - - - DinB family
AFOFKEHG_00383 1.75e-313 VCP - - O - - - AAA domain (dynein-related subfamily)
AFOFKEHG_00384 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
AFOFKEHG_00386 1.79e-55 - - - S - - - YCII-related domain
AFOFKEHG_00387 1.26e-216 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
AFOFKEHG_00388 1.35e-80 yjqA - - S - - - Bacterial PH domain
AFOFKEHG_00389 3.73e-137 yjqB - - S - - - Pfam:DUF867
AFOFKEHG_00390 3.73e-203 yjqC - - P ko:K07217 - ko00000 Catalase
AFOFKEHG_00391 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
AFOFKEHG_00392 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
AFOFKEHG_00394 2.52e-201 xkdB - - K - - - sequence-specific DNA binding
AFOFKEHG_00395 7.48e-153 xkdC - - L - - - Bacterial dnaA protein
AFOFKEHG_00400 2.33e-109 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
AFOFKEHG_00401 3.23e-177 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
AFOFKEHG_00402 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
AFOFKEHG_00403 0.0 yqbA - - S - - - portal protein
AFOFKEHG_00404 1.99e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
AFOFKEHG_00405 3.91e-217 xkdG - - S - - - Phage capsid family
AFOFKEHG_00406 4.68e-82 yqbG - - S - - - Protein of unknown function (DUF3199)
AFOFKEHG_00407 1.75e-84 yqbH - - S - - - Domain of unknown function (DUF3599)
AFOFKEHG_00408 2.78e-113 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
AFOFKEHG_00409 2.87e-101 xkdJ - - - - - - -
AFOFKEHG_00410 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
AFOFKEHG_00411 6.01e-99 xkdM - - S - - - Phage tail tube protein
AFOFKEHG_00412 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
AFOFKEHG_00413 0.0 xkdO - - L - - - Transglycosylase SLT domain
AFOFKEHG_00414 1.77e-158 xkdP - - S - - - Lysin motif
AFOFKEHG_00415 2.31e-232 xkdQ - - G - - - NLP P60 protein
AFOFKEHG_00416 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
AFOFKEHG_00417 1.97e-92 xkdS - - S - - - Protein of unknown function (DUF2634)
AFOFKEHG_00418 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
AFOFKEHG_00419 9.63e-136 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
AFOFKEHG_00420 4.43e-56 - - - - - - - -
AFOFKEHG_00421 0.0 - - - - - - - -
AFOFKEHG_00422 8.68e-74 xkdW - - S - - - XkdW protein
AFOFKEHG_00423 9.34e-33 xkdX - - - - - - -
AFOFKEHG_00424 1.51e-198 xepA - - - - - - -
AFOFKEHG_00425 7.71e-52 xhlA - - S - - - Haemolysin XhlA
AFOFKEHG_00426 8.12e-53 xhlB - - S - - - SPP1 phage holin
AFOFKEHG_00427 1.85e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
AFOFKEHG_00429 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
AFOFKEHG_00430 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
AFOFKEHG_00431 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
AFOFKEHG_00432 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
AFOFKEHG_00433 6.32e-310 steT - - E ko:K03294 - ko00000 amino acid
AFOFKEHG_00434 9.82e-234 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
AFOFKEHG_00435 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AFOFKEHG_00436 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
AFOFKEHG_00437 1.09e-280 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFOFKEHG_00438 9.56e-178 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
AFOFKEHG_00439 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
AFOFKEHG_00440 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFOFKEHG_00441 6.35e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFOFKEHG_00442 6.22e-242 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
AFOFKEHG_00443 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
AFOFKEHG_00445 9.61e-225 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
AFOFKEHG_00446 5.65e-256 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
AFOFKEHG_00447 4.96e-217 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
AFOFKEHG_00448 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
AFOFKEHG_00449 5.69e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
AFOFKEHG_00450 5.95e-204 ykgA - - E - - - Amidinotransferase
AFOFKEHG_00451 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
AFOFKEHG_00452 5.35e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AFOFKEHG_00453 5.85e-13 - - - - - - - -
AFOFKEHG_00454 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
AFOFKEHG_00455 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
AFOFKEHG_00456 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
AFOFKEHG_00457 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
AFOFKEHG_00458 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
AFOFKEHG_00459 1.6e-215 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
AFOFKEHG_00460 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AFOFKEHG_00461 1.87e-288 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AFOFKEHG_00463 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
AFOFKEHG_00464 1.66e-96 ohrR - - K - - - COG1846 Transcriptional regulators
AFOFKEHG_00465 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
AFOFKEHG_00467 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
AFOFKEHG_00468 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AFOFKEHG_00469 3.66e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
AFOFKEHG_00470 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
AFOFKEHG_00471 3.12e-174 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
AFOFKEHG_00472 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_00473 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
AFOFKEHG_00474 4.92e-142 ykoF - - S - - - YKOF-related Family
AFOFKEHG_00475 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFOFKEHG_00476 2.46e-306 ykoH - - T - - - Histidine kinase
AFOFKEHG_00477 1.94e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
AFOFKEHG_00478 2.24e-112 ykoJ - - S - - - Peptidase propeptide and YPEB domain
AFOFKEHG_00479 1.45e-08 - - - - - - - -
AFOFKEHG_00481 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
AFOFKEHG_00482 1.49e-70 tnrA - - K - - - transcriptional
AFOFKEHG_00483 1.63e-25 - - - - - - - -
AFOFKEHG_00484 3.04e-36 ykoL - - - - - - -
AFOFKEHG_00485 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
AFOFKEHG_00486 2.76e-233 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
AFOFKEHG_00487 5.69e-128 ykoP - - G - - - polysaccharide deacetylase
AFOFKEHG_00488 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
AFOFKEHG_00489 0.0 ykoS - - - - - - -
AFOFKEHG_00490 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
AFOFKEHG_00491 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
AFOFKEHG_00492 1.25e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AFOFKEHG_00493 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
AFOFKEHG_00494 1.71e-143 ykoX - - S - - - membrane-associated protein
AFOFKEHG_00495 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
AFOFKEHG_00496 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFOFKEHG_00497 1.9e-190 rsgI - - S - - - Anti-sigma factor N-terminus
AFOFKEHG_00498 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
AFOFKEHG_00499 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
AFOFKEHG_00500 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
AFOFKEHG_00501 3.67e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
AFOFKEHG_00503 8.33e-31 ykzE - - - - - - -
AFOFKEHG_00504 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
AFOFKEHG_00505 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_00506 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AFOFKEHG_00508 1.62e-253 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AFOFKEHG_00509 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AFOFKEHG_00510 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
AFOFKEHG_00511 4.61e-294 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
AFOFKEHG_00512 2.29e-293 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
AFOFKEHG_00513 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AFOFKEHG_00514 1.84e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
AFOFKEHG_00515 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AFOFKEHG_00516 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
AFOFKEHG_00518 5.62e-93 eag - - - - - - -
AFOFKEHG_00519 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
AFOFKEHG_00520 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
AFOFKEHG_00521 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
AFOFKEHG_00522 9.25e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
AFOFKEHG_00523 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
AFOFKEHG_00524 2.36e-227 ykvI - - S - - - membrane
AFOFKEHG_00525 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AFOFKEHG_00526 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
AFOFKEHG_00527 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
AFOFKEHG_00528 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AFOFKEHG_00529 2.8e-81 ykvN - - K - - - Transcriptional regulator
AFOFKEHG_00530 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
AFOFKEHG_00531 1.28e-273 - - - M - - - Glycosyl transferases group 1
AFOFKEHG_00532 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
AFOFKEHG_00533 3.53e-204 - - - G - - - Glycosyl hydrolases family 18
AFOFKEHG_00534 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
AFOFKEHG_00535 5.43e-35 ykvS - - S - - - protein conserved in bacteria
AFOFKEHG_00536 2.6e-39 - - - - - - - -
AFOFKEHG_00537 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
AFOFKEHG_00538 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFOFKEHG_00539 1.31e-113 stoA - - CO - - - thiol-disulfide
AFOFKEHG_00540 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
AFOFKEHG_00541 3.99e-09 - - - - - - - -
AFOFKEHG_00542 6.19e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
AFOFKEHG_00543 1.1e-228 ykvZ - - K - - - Transcriptional regulator
AFOFKEHG_00544 2.29e-166 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
AFOFKEHG_00545 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
AFOFKEHG_00546 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
AFOFKEHG_00547 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AFOFKEHG_00548 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_00549 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
AFOFKEHG_00550 4.2e-160 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFOFKEHG_00551 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
AFOFKEHG_00552 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
AFOFKEHG_00553 5.36e-172 ykwD - - J - - - protein with SCP PR1 domains
AFOFKEHG_00554 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
AFOFKEHG_00555 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_00556 3.44e-282 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
AFOFKEHG_00557 1.05e-22 - - - - - - - -
AFOFKEHG_00558 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
AFOFKEHG_00559 3.71e-110 ykyB - - S - - - YkyB-like protein
AFOFKEHG_00560 8.89e-306 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_00561 7.1e-116 ykuD - - S - - - protein conserved in bacteria
AFOFKEHG_00562 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
AFOFKEHG_00563 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFOFKEHG_00564 0.0 ybfG - - M - - - Putative peptidoglycan binding domain
AFOFKEHG_00565 1.52e-120 - - - M - - - Peptidoglycan-binding domain 1 protein
AFOFKEHG_00567 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
AFOFKEHG_00568 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
AFOFKEHG_00569 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
AFOFKEHG_00570 7.83e-38 ykzF - - S - - - Antirepressor AbbA
AFOFKEHG_00571 5.15e-100 ykuL - - S - - - CBS domain
AFOFKEHG_00572 6.52e-216 ccpC - - K - - - Transcriptional regulator
AFOFKEHG_00573 7.72e-114 - - - C ko:K03839 - ko00000 Flavodoxin domain
AFOFKEHG_00574 1.33e-226 ykuO - - - - - - -
AFOFKEHG_00575 1.3e-104 fld - - C ko:K03839 - ko00000 Flavodoxin
AFOFKEHG_00576 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AFOFKEHG_00577 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AFOFKEHG_00578 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
AFOFKEHG_00579 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
AFOFKEHG_00580 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
AFOFKEHG_00581 6.25e-106 ykuV - - CO - - - thiol-disulfide
AFOFKEHG_00582 4.71e-122 rok - - K - - - Repressor of ComK
AFOFKEHG_00583 1.47e-201 yknT - - - ko:K06437 - ko00000 -
AFOFKEHG_00584 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
AFOFKEHG_00585 6.5e-246 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
AFOFKEHG_00586 1.05e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
AFOFKEHG_00587 3.44e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
AFOFKEHG_00588 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
AFOFKEHG_00589 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AFOFKEHG_00590 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
AFOFKEHG_00591 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
AFOFKEHG_00592 1.6e-151 yknW - - S - - - Yip1 domain
AFOFKEHG_00593 4.93e-235 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AFOFKEHG_00594 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_00595 2.1e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
AFOFKEHG_00596 1.49e-175 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_00597 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
AFOFKEHG_00598 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
AFOFKEHG_00599 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
AFOFKEHG_00600 5.43e-52 ykoA - - - - - - -
AFOFKEHG_00601 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
AFOFKEHG_00602 2.99e-217 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AFOFKEHG_00603 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
AFOFKEHG_00604 1.09e-18 - - - S - - - Uncharacterized protein YkpC
AFOFKEHG_00605 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
AFOFKEHG_00606 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
AFOFKEHG_00607 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
AFOFKEHG_00608 3.42e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
AFOFKEHG_00609 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
AFOFKEHG_00610 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AFOFKEHG_00611 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFOFKEHG_00612 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
AFOFKEHG_00613 4.79e-186 ykrA - - S - - - hydrolases of the HAD superfamily
AFOFKEHG_00614 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AFOFKEHG_00615 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
AFOFKEHG_00616 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
AFOFKEHG_00617 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
AFOFKEHG_00618 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AFOFKEHG_00619 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AFOFKEHG_00620 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
AFOFKEHG_00621 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
AFOFKEHG_00622 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
AFOFKEHG_00623 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
AFOFKEHG_00624 1.3e-152 yktB - - S - - - Belongs to the UPF0637 family
AFOFKEHG_00625 4.48e-35 ykzI - - - - - - -
AFOFKEHG_00626 7.8e-194 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
AFOFKEHG_00627 2.45e-99 ykzC - - S - - - Acetyltransferase (GNAT) family
AFOFKEHG_00628 5.82e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AFOFKEHG_00629 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
AFOFKEHG_00630 0.0 ylaA - - - - - - -
AFOFKEHG_00631 1.44e-56 ylaB - - - - - - -
AFOFKEHG_00632 2.93e-114 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
AFOFKEHG_00634 1.74e-57 ylaE - - - - - - -
AFOFKEHG_00635 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
AFOFKEHG_00636 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
AFOFKEHG_00637 4.4e-63 ylaH - - S - - - YlaH-like protein
AFOFKEHG_00638 8.92e-44 ylaI - - S - - - protein conserved in bacteria
AFOFKEHG_00639 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
AFOFKEHG_00640 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
AFOFKEHG_00641 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AFOFKEHG_00642 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
AFOFKEHG_00643 5.71e-58 ylaN - - S - - - Belongs to the UPF0358 family
AFOFKEHG_00644 3e-272 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
AFOFKEHG_00645 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AFOFKEHG_00646 2e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
AFOFKEHG_00647 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
AFOFKEHG_00648 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
AFOFKEHG_00649 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AFOFKEHG_00650 6.17e-144 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
AFOFKEHG_00651 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
AFOFKEHG_00652 1.21e-213 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
AFOFKEHG_00653 1.61e-81 ylbA - - S - - - YugN-like family
AFOFKEHG_00654 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
AFOFKEHG_00655 6.24e-256 ylbC - - S - - - protein with SCP PR1 domains
AFOFKEHG_00656 3.24e-89 ylbD - - S - - - Putative coat protein
AFOFKEHG_00657 1.73e-48 ylbE - - S - - - YlbE-like protein
AFOFKEHG_00658 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
AFOFKEHG_00659 5.1e-51 ylbG - - S - - - UPF0298 protein
AFOFKEHG_00660 8.27e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
AFOFKEHG_00661 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AFOFKEHG_00662 5.5e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
AFOFKEHG_00663 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
AFOFKEHG_00664 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
AFOFKEHG_00665 2.48e-293 ylbM - - S - - - Belongs to the UPF0348 family
AFOFKEHG_00667 3.44e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
AFOFKEHG_00668 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
AFOFKEHG_00669 5.75e-108 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
AFOFKEHG_00670 3.26e-116 ylbP - - K - - - n-acetyltransferase
AFOFKEHG_00671 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AFOFKEHG_00672 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AFOFKEHG_00673 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
AFOFKEHG_00674 4.76e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AFOFKEHG_00675 3.42e-68 ftsL - - D - - - Essential cell division protein
AFOFKEHG_00676 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
AFOFKEHG_00677 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
AFOFKEHG_00678 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AFOFKEHG_00679 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AFOFKEHG_00680 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AFOFKEHG_00681 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
AFOFKEHG_00682 7.74e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AFOFKEHG_00683 3.74e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
AFOFKEHG_00684 3.37e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AFOFKEHG_00685 1.35e-143 ylxW - - S - - - protein conserved in bacteria
AFOFKEHG_00686 8.67e-132 ylxX - - S - - - protein conserved in bacteria
AFOFKEHG_00687 5.37e-76 sbp - - S - - - small basic protein
AFOFKEHG_00688 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AFOFKEHG_00689 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AFOFKEHG_00690 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
AFOFKEHG_00692 1.23e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
AFOFKEHG_00693 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFOFKEHG_00694 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFOFKEHG_00695 9.05e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
AFOFKEHG_00696 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
AFOFKEHG_00697 3.58e-51 ylmC - - S - - - sporulation protein
AFOFKEHG_00698 3.73e-203 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
AFOFKEHG_00699 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AFOFKEHG_00700 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
AFOFKEHG_00701 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
AFOFKEHG_00702 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
AFOFKEHG_00703 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
AFOFKEHG_00704 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AFOFKEHG_00705 3.74e-82 ylyA - - T - - - COG1734 DnaK suppressor protein
AFOFKEHG_00706 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AFOFKEHG_00707 2.04e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
AFOFKEHG_00708 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AFOFKEHG_00709 1.97e-291 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
AFOFKEHG_00710 4.21e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
AFOFKEHG_00711 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AFOFKEHG_00712 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
AFOFKEHG_00713 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
AFOFKEHG_00714 3.84e-185 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
AFOFKEHG_00715 1.33e-224 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AFOFKEHG_00716 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AFOFKEHG_00717 3.8e-150 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AFOFKEHG_00719 3.58e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
AFOFKEHG_00720 7.32e-230 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
AFOFKEHG_00721 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
AFOFKEHG_00722 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
AFOFKEHG_00723 1.24e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
AFOFKEHG_00724 4.33e-189 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
AFOFKEHG_00725 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
AFOFKEHG_00726 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
AFOFKEHG_00727 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
AFOFKEHG_00728 8.41e-202 yloC - - S - - - stress-induced protein
AFOFKEHG_00729 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
AFOFKEHG_00730 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
AFOFKEHG_00731 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AFOFKEHG_00732 4.59e-289 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AFOFKEHG_00733 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AFOFKEHG_00734 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AFOFKEHG_00735 2.21e-226 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AFOFKEHG_00736 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AFOFKEHG_00737 3.73e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AFOFKEHG_00738 3.03e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
AFOFKEHG_00739 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
AFOFKEHG_00740 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AFOFKEHG_00741 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
AFOFKEHG_00742 2.83e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
AFOFKEHG_00743 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
AFOFKEHG_00744 3.65e-78 yloU - - S - - - protein conserved in bacteria
AFOFKEHG_00745 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
AFOFKEHG_00746 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
AFOFKEHG_00747 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
AFOFKEHG_00748 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AFOFKEHG_00749 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
AFOFKEHG_00750 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AFOFKEHG_00751 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
AFOFKEHG_00752 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
AFOFKEHG_00753 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
AFOFKEHG_00754 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AFOFKEHG_00755 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
AFOFKEHG_00756 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AFOFKEHG_00757 1.67e-114 - - - - - - - -
AFOFKEHG_00758 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AFOFKEHG_00759 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AFOFKEHG_00760 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
AFOFKEHG_00761 2.95e-50 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
AFOFKEHG_00762 5.89e-81 ylqD - - S - - - YlqD protein
AFOFKEHG_00763 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AFOFKEHG_00764 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
AFOFKEHG_00765 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AFOFKEHG_00766 1.4e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AFOFKEHG_00767 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFOFKEHG_00768 0.0 ylqG - - - - - - -
AFOFKEHG_00769 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
AFOFKEHG_00770 9.61e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
AFOFKEHG_00771 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AFOFKEHG_00772 3.62e-215 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
AFOFKEHG_00773 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AFOFKEHG_00774 9.03e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AFOFKEHG_00775 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
AFOFKEHG_00776 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AFOFKEHG_00777 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AFOFKEHG_00778 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AFOFKEHG_00779 1.89e-82 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
AFOFKEHG_00780 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
AFOFKEHG_00781 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
AFOFKEHG_00782 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
AFOFKEHG_00783 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
AFOFKEHG_00784 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
AFOFKEHG_00785 2.11e-308 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
AFOFKEHG_00786 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
AFOFKEHG_00787 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
AFOFKEHG_00788 1.9e-313 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
AFOFKEHG_00789 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
AFOFKEHG_00790 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
AFOFKEHG_00791 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
AFOFKEHG_00792 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
AFOFKEHG_00793 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AFOFKEHG_00794 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
AFOFKEHG_00795 5.54e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
AFOFKEHG_00796 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
AFOFKEHG_00797 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
AFOFKEHG_00798 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
AFOFKEHG_00799 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AFOFKEHG_00800 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AFOFKEHG_00801 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
AFOFKEHG_00802 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
AFOFKEHG_00803 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
AFOFKEHG_00804 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
AFOFKEHG_00805 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
AFOFKEHG_00806 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
AFOFKEHG_00807 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
AFOFKEHG_00808 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFOFKEHG_00809 6.91e-101 ylxL - - - - - - -
AFOFKEHG_00810 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
AFOFKEHG_00811 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AFOFKEHG_00812 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
AFOFKEHG_00813 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AFOFKEHG_00814 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AFOFKEHG_00815 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
AFOFKEHG_00816 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
AFOFKEHG_00817 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
AFOFKEHG_00818 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AFOFKEHG_00819 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFOFKEHG_00820 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
AFOFKEHG_00821 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
AFOFKEHG_00822 5.78e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
AFOFKEHG_00823 6.16e-63 ylxQ - - J - - - ribosomal protein
AFOFKEHG_00824 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AFOFKEHG_00825 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
AFOFKEHG_00826 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AFOFKEHG_00827 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AFOFKEHG_00828 1.34e-231 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
AFOFKEHG_00829 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AFOFKEHG_00830 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
AFOFKEHG_00831 2.92e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
AFOFKEHG_00832 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
AFOFKEHG_00833 1.53e-56 ymxH - - S - - - YlmC YmxH family
AFOFKEHG_00834 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
AFOFKEHG_00835 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
AFOFKEHG_00836 4.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AFOFKEHG_00837 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
AFOFKEHG_00838 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AFOFKEHG_00839 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFOFKEHG_00840 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
AFOFKEHG_00841 4.94e-44 - - - S - - - YlzJ-like protein
AFOFKEHG_00842 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
AFOFKEHG_00843 3.68e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_00844 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_00845 1.35e-298 albE - - S - - - Peptidase M16
AFOFKEHG_00846 6.8e-309 ymfH - - S - - - zinc protease
AFOFKEHG_00847 1.49e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
AFOFKEHG_00848 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
AFOFKEHG_00849 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
AFOFKEHG_00850 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
AFOFKEHG_00851 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFOFKEHG_00852 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
AFOFKEHG_00853 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AFOFKEHG_00854 8.43e-282 pbpX - - V - - - Beta-lactamase
AFOFKEHG_00855 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
AFOFKEHG_00856 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
AFOFKEHG_00857 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
AFOFKEHG_00858 3.53e-254 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
AFOFKEHG_00859 1.02e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
AFOFKEHG_00860 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AFOFKEHG_00861 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
AFOFKEHG_00862 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
AFOFKEHG_00863 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AFOFKEHG_00864 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AFOFKEHG_00865 7.19e-93 - - - S - - - Regulatory protein YrvL
AFOFKEHG_00867 1.38e-127 ymcC - - S - - - Membrane
AFOFKEHG_00868 2.94e-141 pksA - - K - - - Transcriptional regulator
AFOFKEHG_00869 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
AFOFKEHG_00870 1.31e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
AFOFKEHG_00871 2.42e-238 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
AFOFKEHG_00872 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
AFOFKEHG_00873 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
AFOFKEHG_00874 5.31e-304 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AFOFKEHG_00875 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
AFOFKEHG_00876 2.48e-184 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
AFOFKEHG_00877 2.69e-177 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
AFOFKEHG_00878 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
AFOFKEHG_00879 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
AFOFKEHG_00880 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
AFOFKEHG_00881 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
AFOFKEHG_00882 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
AFOFKEHG_00883 6.56e-293 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
AFOFKEHG_00884 8.03e-81 ymzB - - - - - - -
AFOFKEHG_00885 1.27e-205 - - - S - - - Metallo-beta-lactamase superfamily
AFOFKEHG_00886 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
AFOFKEHG_00888 3.96e-163 ymaC - - S - - - Replication protein
AFOFKEHG_00889 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
AFOFKEHG_00890 6.39e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
AFOFKEHG_00891 8.23e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
AFOFKEHG_00893 5.41e-76 ymaF - - S - - - YmaF family
AFOFKEHG_00894 7.96e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AFOFKEHG_00895 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
AFOFKEHG_00896 2.69e-30 - - - - - - - -
AFOFKEHG_00897 1.2e-30 ymzA - - - - - - -
AFOFKEHG_00898 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
AFOFKEHG_00899 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFOFKEHG_00900 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFOFKEHG_00901 1.29e-140 - - - - - - - -
AFOFKEHG_00902 3.32e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
AFOFKEHG_00903 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
AFOFKEHG_00904 4.47e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AFOFKEHG_00905 5.82e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
AFOFKEHG_00906 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
AFOFKEHG_00907 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
AFOFKEHG_00908 2.95e-14 - - - - - - - -
AFOFKEHG_00909 2.61e-40 - - - - - - - -
AFOFKEHG_00910 7.13e-52 - - - - - - - -
AFOFKEHG_00911 5.4e-105 - - - G - - - regulation of fungal-type cell wall biogenesis
AFOFKEHG_00912 1.97e-186 ynaC - - - - - - -
AFOFKEHG_00913 7.56e-129 ynaD - - J - - - Acetyltransferase (GNAT) domain
AFOFKEHG_00914 1.65e-160 - - - S - - - Domain of unknown function (DUF3885)
AFOFKEHG_00915 1.06e-80 ynaF - - - - - - -
AFOFKEHG_00918 4.32e-110 - - - E - - - phosphoribosylanthranilate isomerase activity
AFOFKEHG_00919 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
AFOFKEHG_00920 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
AFOFKEHG_00921 5.85e-274 xylR - - GK - - - ROK family
AFOFKEHG_00922 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
AFOFKEHG_00923 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
AFOFKEHG_00924 2.92e-144 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
AFOFKEHG_00925 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
AFOFKEHG_00926 2.06e-279 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AFOFKEHG_00927 6.41e-106 - - - S - - - Protein of unknown function (DUF2691)
AFOFKEHG_00928 9.28e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
AFOFKEHG_00929 7.54e-22 - - - - - - - -
AFOFKEHG_00932 1.31e-208 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AFOFKEHG_00934 2.11e-170 - - - S - - - Domain of unknown function, YrpD
AFOFKEHG_00937 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
AFOFKEHG_00938 8.92e-96 - - - - - - - -
AFOFKEHG_00939 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
AFOFKEHG_00942 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
AFOFKEHG_00943 2.38e-251 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
AFOFKEHG_00944 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
AFOFKEHG_00945 9.15e-199 yndG - - S - - - DoxX-like family
AFOFKEHG_00946 1.26e-151 - - - S - - - Domain of unknown function (DUF4166)
AFOFKEHG_00947 0.0 yndJ - - S - - - YndJ-like protein
AFOFKEHG_00949 1.68e-177 yndL - - S - - - Replication protein
AFOFKEHG_00950 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
AFOFKEHG_00951 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
AFOFKEHG_00953 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AFOFKEHG_00954 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
AFOFKEHG_00955 3.97e-145 yneB - - L - - - resolvase
AFOFKEHG_00956 1.15e-43 ynzC - - S - - - UPF0291 protein
AFOFKEHG_00957 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AFOFKEHG_00958 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
AFOFKEHG_00959 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
AFOFKEHG_00960 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
AFOFKEHG_00961 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
AFOFKEHG_00962 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
AFOFKEHG_00963 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
AFOFKEHG_00964 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
AFOFKEHG_00965 1.21e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
AFOFKEHG_00966 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
AFOFKEHG_00967 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
AFOFKEHG_00968 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AFOFKEHG_00969 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AFOFKEHG_00970 9.26e-10 - - - S - - - Fur-regulated basic protein B
AFOFKEHG_00972 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
AFOFKEHG_00973 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
AFOFKEHG_00974 1.63e-71 yneQ - - - - - - -
AFOFKEHG_00975 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
AFOFKEHG_00976 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AFOFKEHG_00977 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
AFOFKEHG_00978 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AFOFKEHG_00979 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AFOFKEHG_00980 1.82e-18 - - - - - - - -
AFOFKEHG_00981 1.06e-75 ynfC - - - - - - -
AFOFKEHG_00982 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
AFOFKEHG_00983 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
AFOFKEHG_00985 0.0 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
AFOFKEHG_00986 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
AFOFKEHG_00987 1.04e-104 yngA - - S - - - membrane
AFOFKEHG_00988 4.54e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
AFOFKEHG_00989 2.01e-134 yngC - - S - - - membrane-associated protein
AFOFKEHG_00990 4.46e-297 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
AFOFKEHG_00991 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
AFOFKEHG_00992 1.48e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
AFOFKEHG_00993 7.02e-214 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
AFOFKEHG_00994 1.23e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
AFOFKEHG_00995 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
AFOFKEHG_00996 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
AFOFKEHG_00997 1.31e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
AFOFKEHG_00998 4.3e-41 - - - S - - - Family of unknown function (DUF5367)
AFOFKEHG_00999 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
AFOFKEHG_01000 2.12e-84 yngL - - S - - - Protein of unknown function (DUF1360)
AFOFKEHG_01001 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
AFOFKEHG_01002 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFOFKEHG_01003 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
AFOFKEHG_01004 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
AFOFKEHG_01005 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
AFOFKEHG_01006 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
AFOFKEHG_01007 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AFOFKEHG_01008 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AFOFKEHG_01009 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
AFOFKEHG_01010 7.42e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
AFOFKEHG_01011 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
AFOFKEHG_01012 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AFOFKEHG_01013 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
AFOFKEHG_01014 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
AFOFKEHG_01015 1.68e-94 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AFOFKEHG_01016 4.29e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFOFKEHG_01017 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
AFOFKEHG_01018 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
AFOFKEHG_01019 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
AFOFKEHG_01020 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
AFOFKEHG_01021 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AFOFKEHG_01022 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AFOFKEHG_01023 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AFOFKEHG_01024 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AFOFKEHG_01025 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
AFOFKEHG_01026 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFOFKEHG_01027 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFOFKEHG_01028 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
AFOFKEHG_01029 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AFOFKEHG_01030 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AFOFKEHG_01031 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AFOFKEHG_01032 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AFOFKEHG_01033 8.78e-238 ybaC - - S - - - Alpha/beta hydrolase family
AFOFKEHG_01034 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
AFOFKEHG_01035 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AFOFKEHG_01036 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
AFOFKEHG_01037 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AFOFKEHG_01038 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AFOFKEHG_01039 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AFOFKEHG_01040 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AFOFKEHG_01041 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AFOFKEHG_01042 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AFOFKEHG_01043 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
AFOFKEHG_01044 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AFOFKEHG_01045 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AFOFKEHG_01046 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AFOFKEHG_01047 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AFOFKEHG_01048 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AFOFKEHG_01049 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AFOFKEHG_01050 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AFOFKEHG_01051 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AFOFKEHG_01052 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AFOFKEHG_01053 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
AFOFKEHG_01054 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
AFOFKEHG_01055 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AFOFKEHG_01056 6.17e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AFOFKEHG_01057 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
AFOFKEHG_01058 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AFOFKEHG_01059 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
AFOFKEHG_01060 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AFOFKEHG_01061 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AFOFKEHG_01062 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFOFKEHG_01063 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
AFOFKEHG_01064 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFOFKEHG_01065 9.4e-198 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFOFKEHG_01066 3.23e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFOFKEHG_01067 6.15e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AFOFKEHG_01068 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AFOFKEHG_01069 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
AFOFKEHG_01070 6.15e-186 ybaJ - - Q - - - Methyltransferase domain
AFOFKEHG_01071 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
AFOFKEHG_01072 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
AFOFKEHG_01073 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
AFOFKEHG_01074 1.04e-122 gerD - - - ko:K06294 - ko00000 -
AFOFKEHG_01075 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
AFOFKEHG_01076 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
AFOFKEHG_01077 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
AFOFKEHG_01078 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
AFOFKEHG_01079 5.05e-260 yaaN - - P - - - Belongs to the TelA family
AFOFKEHG_01080 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
AFOFKEHG_01081 1.34e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AFOFKEHG_01082 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
AFOFKEHG_01083 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
AFOFKEHG_01084 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
AFOFKEHG_01085 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
AFOFKEHG_01086 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
AFOFKEHG_01087 1.14e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
AFOFKEHG_01088 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
AFOFKEHG_01089 7.26e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AFOFKEHG_01090 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
AFOFKEHG_01091 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AFOFKEHG_01092 5.05e-185 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
AFOFKEHG_01093 1.91e-283 yabE - - T - - - protein conserved in bacteria
AFOFKEHG_01094 1.05e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AFOFKEHG_01095 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AFOFKEHG_01096 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
AFOFKEHG_01097 5.32e-53 veg - - S - - - protein conserved in bacteria
AFOFKEHG_01098 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
AFOFKEHG_01099 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AFOFKEHG_01100 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
AFOFKEHG_01101 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
AFOFKEHG_01102 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
AFOFKEHG_01103 9e-310 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AFOFKEHG_01104 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AFOFKEHG_01105 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AFOFKEHG_01106 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AFOFKEHG_01107 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
AFOFKEHG_01108 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AFOFKEHG_01109 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
AFOFKEHG_01110 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFOFKEHG_01111 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
AFOFKEHG_01112 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
AFOFKEHG_01113 1.91e-66 yabP - - S - - - Sporulation protein YabP
AFOFKEHG_01114 1.23e-136 yabQ - - S - - - spore cortex biosynthesis protein
AFOFKEHG_01115 6.94e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
AFOFKEHG_01116 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
AFOFKEHG_01119 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
AFOFKEHG_01120 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
AFOFKEHG_01121 6.92e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
AFOFKEHG_01122 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AFOFKEHG_01123 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
AFOFKEHG_01124 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFOFKEHG_01125 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AFOFKEHG_01126 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AFOFKEHG_01127 1.7e-204 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
AFOFKEHG_01128 4.4e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
AFOFKEHG_01129 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AFOFKEHG_01130 5.98e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
AFOFKEHG_01131 1.79e-213 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
AFOFKEHG_01132 9.52e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AFOFKEHG_01133 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AFOFKEHG_01134 2.64e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AFOFKEHG_01135 1.81e-41 yazB - - K - - - transcriptional
AFOFKEHG_01136 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AFOFKEHG_01137 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
AFOFKEHG_01138 0.0 xkdO - - L - - - Transglycosylase SLT domain
AFOFKEHG_01139 1.08e-90 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
AFOFKEHG_01140 8.21e-97 xkdM - - S - - - Phage tail tube protein
AFOFKEHG_01141 8.34e-311 xkdK - - S - - - Phage tail sheath C-terminal domain
AFOFKEHG_01142 4.96e-32 - - - - - - - -
AFOFKEHG_01143 4.94e-88 yqbJ - - - - - - -
AFOFKEHG_01144 3.75e-114 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
AFOFKEHG_01145 1.38e-73 yqbH - - S - - - Domain of unknown function (DUF3599)
AFOFKEHG_01146 1.88e-60 - - - S - - - Protein of unknown function (DUF3199)
AFOFKEHG_01147 6.49e-28 - - - S - - - YqbF, hypothetical protein domain
AFOFKEHG_01148 2.12e-189 xkdG - - S - - - Phage capsid family
AFOFKEHG_01149 4.06e-132 yqbD - - L - - - Putative phage serine protease XkdF
AFOFKEHG_01151 1.23e-185 - - - S - - - Phage Mu protein F like protein
AFOFKEHG_01152 2.37e-314 yqbA - - S - - - portal protein
AFOFKEHG_01153 1.16e-295 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
AFOFKEHG_01154 4.51e-103 - - - - - - - -
AFOFKEHG_01155 6.96e-36 - - - - - - - -
AFOFKEHG_01156 2.13e-160 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
AFOFKEHG_01157 3.73e-70 - - - K - - - DNA binding
AFOFKEHG_01159 3.56e-05 - - - - - - - -
AFOFKEHG_01161 1.73e-50 - - - - - - - -
AFOFKEHG_01162 3.07e-76 - - - - - - - -
AFOFKEHG_01165 1.68e-238 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
AFOFKEHG_01168 7.84e-34 - - - - - - - -
AFOFKEHG_01172 7.11e-97 - - - - - - - -
AFOFKEHG_01173 1.03e-63 - 3.1.22.4 - - ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 -
AFOFKEHG_01176 2.63e-227 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
AFOFKEHG_01178 1.46e-34 - - - L - - - primosome component and related proteins
AFOFKEHG_01180 6.22e-134 - - - S - - - Metallo-beta-lactamase superfamily
AFOFKEHG_01181 4e-143 - - - L ko:K07455 - ko00000,ko03400 RecT family
AFOFKEHG_01183 1.9e-228 - - - D - - - nuclear chromosome segregation
AFOFKEHG_01187 2.32e-57 - - - - - - - -
AFOFKEHG_01188 2.87e-15 - - - S - - - Helix-turn-helix domain
AFOFKEHG_01190 1.41e-23 - - - K - - - Helix-turn-helix domain
AFOFKEHG_01192 2.54e-31 xkdA - - E - - - IrrE N-terminal-like domain
AFOFKEHG_01193 1.01e-100 - - - L - - - Phage integrase, N-terminal SAM-like domain
AFOFKEHG_01196 2.14e-232 yaaC - - S - - - YaaC-like Protein
AFOFKEHG_01197 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
AFOFKEHG_01198 1.03e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
AFOFKEHG_01199 1.06e-201 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AFOFKEHG_01200 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AFOFKEHG_01201 2.3e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AFOFKEHG_01203 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
AFOFKEHG_01204 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
AFOFKEHG_01205 2.57e-276 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
AFOFKEHG_01206 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
AFOFKEHG_01207 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AFOFKEHG_01208 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFOFKEHG_01209 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AFOFKEHG_01210 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AFOFKEHG_01211 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
AFOFKEHG_01212 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
AFOFKEHG_01213 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFOFKEHG_01214 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFOFKEHG_01219 1.25e-10 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AFOFKEHG_01221 1.36e-49 - - - S - - - YolD-like protein
AFOFKEHG_01223 1.27e-200 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
AFOFKEHG_01224 1.35e-228 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
AFOFKEHG_01225 4.42e-35 - - - - - - - -
AFOFKEHG_01226 1.19e-159 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
AFOFKEHG_01227 1.65e-43 xhlB - - S - - - SPP1 phage holin
AFOFKEHG_01228 2.42e-36 xhlA - - S - - - Haemolysin XhlA
AFOFKEHG_01229 1.53e-191 xepA - - - - - - -
AFOFKEHG_01230 7.19e-28 - - - - - - - -
AFOFKEHG_01231 3.27e-60 xkdW - - S - - - XkdW protein
AFOFKEHG_01232 2.63e-219 - - - - - - - -
AFOFKEHG_01233 2.12e-45 - - - - - - - -
AFOFKEHG_01234 8.42e-82 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
AFOFKEHG_01235 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFOFKEHG_01236 1.24e-272 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFOFKEHG_01238 5.43e-05 - 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase-like
AFOFKEHG_01239 0.0 - - - M - - - Glycosyltransferase like family 2
AFOFKEHG_01240 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
AFOFKEHG_01241 2.12e-87 xkdS - - S - - - Protein of unknown function (DUF2634)
AFOFKEHG_01242 3.46e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
AFOFKEHG_01243 2.16e-88 xkdQ - - G - - - NLP P60 protein
AFOFKEHG_01244 7.91e-87 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
AFOFKEHG_01245 3e-54 - - - - - - - -
AFOFKEHG_01246 2.91e-283 - - - - - - - -
AFOFKEHG_01247 1.01e-73 xkdW - - S - - - XkdW protein
AFOFKEHG_01248 9.34e-33 - - - - - - - -
AFOFKEHG_01249 2.01e-212 xepA - - - - - - -
AFOFKEHG_01250 8.36e-89 - - - S - - - Bacteriophage holin family
AFOFKEHG_01251 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
AFOFKEHG_01253 5.4e-80 - - - - - - - -
AFOFKEHG_01255 1.6e-134 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
AFOFKEHG_01256 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
AFOFKEHG_01259 8.68e-120 - - - S - - - Tetratricopeptide repeat
AFOFKEHG_01260 2.08e-197 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
AFOFKEHG_01261 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
AFOFKEHG_01262 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFOFKEHG_01263 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
AFOFKEHG_01264 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
AFOFKEHG_01265 0.0 - - - L ko:K06400 - ko00000 Recombinase
AFOFKEHG_01266 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFOFKEHG_01267 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
AFOFKEHG_01268 9.38e-171 - - - - - - - -
AFOFKEHG_01269 6.53e-218 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
AFOFKEHG_01270 3.97e-136 yqeD - - S - - - SNARE associated Golgi protein
AFOFKEHG_01271 7.45e-180 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
AFOFKEHG_01272 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
AFOFKEHG_01274 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
AFOFKEHG_01275 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
AFOFKEHG_01276 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AFOFKEHG_01277 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
AFOFKEHG_01278 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AFOFKEHG_01279 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
AFOFKEHG_01280 9.76e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AFOFKEHG_01281 9.8e-179 yqeM - - Q - - - Methyltransferase
AFOFKEHG_01282 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AFOFKEHG_01283 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
AFOFKEHG_01284 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
AFOFKEHG_01285 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
AFOFKEHG_01286 2.36e-22 - - - S - - - YqzM-like protein
AFOFKEHG_01287 2.01e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
AFOFKEHG_01288 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
AFOFKEHG_01289 4.16e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AFOFKEHG_01290 9.53e-284 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
AFOFKEHG_01291 6.28e-73 yqxA - - S - - - Protein of unknown function (DUF3679)
AFOFKEHG_01292 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AFOFKEHG_01293 4.3e-278 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
AFOFKEHG_01294 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AFOFKEHG_01295 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AFOFKEHG_01296 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
AFOFKEHG_01297 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AFOFKEHG_01298 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
AFOFKEHG_01299 1.01e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AFOFKEHG_01300 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
AFOFKEHG_01301 3.45e-202 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
AFOFKEHG_01302 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
AFOFKEHG_01303 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
AFOFKEHG_01304 7.97e-292 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
AFOFKEHG_01305 4.35e-192 yqfA - - S - - - UPF0365 protein
AFOFKEHG_01306 3.13e-79 yqfB - - - - - - -
AFOFKEHG_01307 2.07e-60 yqfC - - S - - - sporulation protein YqfC
AFOFKEHG_01308 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
AFOFKEHG_01309 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
AFOFKEHG_01311 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
AFOFKEHG_01312 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AFOFKEHG_01313 1.42e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
AFOFKEHG_01314 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
AFOFKEHG_01315 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AFOFKEHG_01316 5.29e-27 - - - S - - - YqzL-like protein
AFOFKEHG_01317 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
AFOFKEHG_01318 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
AFOFKEHG_01319 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
AFOFKEHG_01320 3.29e-144 ccpN - - K - - - CBS domain
AFOFKEHG_01321 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
AFOFKEHG_01322 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
AFOFKEHG_01323 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AFOFKEHG_01324 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AFOFKEHG_01325 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
AFOFKEHG_01326 2.41e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
AFOFKEHG_01327 7.29e-267 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AFOFKEHG_01328 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AFOFKEHG_01329 5.25e-49 yqfQ - - S - - - YqfQ-like protein
AFOFKEHG_01330 3.82e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AFOFKEHG_01331 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AFOFKEHG_01332 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
AFOFKEHG_01333 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
AFOFKEHG_01334 2.47e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
AFOFKEHG_01335 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
AFOFKEHG_01336 2.38e-80 yqfX - - S - - - membrane
AFOFKEHG_01337 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AFOFKEHG_01338 2.84e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
AFOFKEHG_01339 2.05e-99 yqgA - - - - - - -
AFOFKEHG_01340 9.27e-172 yqgB - - S - - - Protein of unknown function (DUF1189)
AFOFKEHG_01341 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
AFOFKEHG_01342 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
AFOFKEHG_01343 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
AFOFKEHG_01344 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
AFOFKEHG_01345 5.26e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
AFOFKEHG_01346 1.43e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
AFOFKEHG_01347 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
AFOFKEHG_01348 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFOFKEHG_01349 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFOFKEHG_01350 2.92e-98 yqzC - - S - - - YceG-like family
AFOFKEHG_01351 3.42e-68 yqzD - - - - - - -
AFOFKEHG_01353 1.88e-33 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
AFOFKEHG_01354 2.12e-215 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
AFOFKEHG_01355 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
AFOFKEHG_01356 2.38e-138 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AFOFKEHG_01357 3.38e-14 yqgO - - - - - - -
AFOFKEHG_01358 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
AFOFKEHG_01359 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
AFOFKEHG_01360 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
AFOFKEHG_01361 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
AFOFKEHG_01362 3.04e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
AFOFKEHG_01363 5.65e-258 yqgU - - - - - - -
AFOFKEHG_01364 7.34e-66 yqgV - - S - - - Thiamine-binding protein
AFOFKEHG_01365 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
AFOFKEHG_01366 7.54e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
AFOFKEHG_01367 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
AFOFKEHG_01368 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
AFOFKEHG_01370 7.14e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
AFOFKEHG_01371 5.77e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
AFOFKEHG_01372 1.19e-230 yqxL - - P - - - Mg2 transporter protein
AFOFKEHG_01373 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AFOFKEHG_01374 1.29e-220 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
AFOFKEHG_01375 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
AFOFKEHG_01376 9.7e-94 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
AFOFKEHG_01377 4.35e-79 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
AFOFKEHG_01378 3.44e-65 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
AFOFKEHG_01379 2.55e-55 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
AFOFKEHG_01380 4.9e-37 yqzE - - S - - - YqzE-like protein
AFOFKEHG_01381 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
AFOFKEHG_01382 2.29e-155 yqxM - - - ko:K19433 - ko00000 -
AFOFKEHG_01383 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
AFOFKEHG_01384 1.28e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
AFOFKEHG_01385 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
AFOFKEHG_01386 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
AFOFKEHG_01387 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
AFOFKEHG_01388 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
AFOFKEHG_01389 5.49e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
AFOFKEHG_01390 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AFOFKEHG_01391 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AFOFKEHG_01392 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
AFOFKEHG_01393 1.12e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
AFOFKEHG_01394 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
AFOFKEHG_01395 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
AFOFKEHG_01396 5.18e-81 yqhP - - - - - - -
AFOFKEHG_01397 4.42e-222 yqhQ - - S - - - Protein of unknown function (DUF1385)
AFOFKEHG_01398 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
AFOFKEHG_01399 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
AFOFKEHG_01400 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
AFOFKEHG_01401 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AFOFKEHG_01402 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
AFOFKEHG_01403 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
AFOFKEHG_01404 6.93e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
AFOFKEHG_01405 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
AFOFKEHG_01406 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
AFOFKEHG_01407 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
AFOFKEHG_01408 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
AFOFKEHG_01409 9.25e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
AFOFKEHG_01410 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
AFOFKEHG_01411 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AFOFKEHG_01412 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
AFOFKEHG_01413 1.65e-88 yqhY - - S - - - protein conserved in bacteria
AFOFKEHG_01414 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AFOFKEHG_01415 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AFOFKEHG_01416 2.5e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AFOFKEHG_01417 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AFOFKEHG_01418 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
AFOFKEHG_01419 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AFOFKEHG_01420 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
AFOFKEHG_01421 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
AFOFKEHG_01422 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
AFOFKEHG_01423 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
AFOFKEHG_01424 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
AFOFKEHG_01426 1.77e-276 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
AFOFKEHG_01427 2.26e-37 - - - - - - - -
AFOFKEHG_01428 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
AFOFKEHG_01429 3.68e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
AFOFKEHG_01430 5.7e-281 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
AFOFKEHG_01431 7.2e-201 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
AFOFKEHG_01432 5.16e-270 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
AFOFKEHG_01433 1.66e-267 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
AFOFKEHG_01434 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
AFOFKEHG_01435 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AFOFKEHG_01436 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
AFOFKEHG_01437 0.0 bkdR - - KT - - - Transcriptional regulator
AFOFKEHG_01438 1.74e-198 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
AFOFKEHG_01439 2.24e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
AFOFKEHG_01440 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
AFOFKEHG_01441 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
AFOFKEHG_01442 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
AFOFKEHG_01443 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AFOFKEHG_01444 1.57e-296 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AFOFKEHG_01445 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
AFOFKEHG_01446 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_01447 4.23e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
AFOFKEHG_01448 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
AFOFKEHG_01449 1.18e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
AFOFKEHG_01450 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
AFOFKEHG_01451 5.2e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
AFOFKEHG_01452 1.88e-225 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
AFOFKEHG_01453 2.41e-128 yqjB - - S - - - protein conserved in bacteria
AFOFKEHG_01455 7.75e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
AFOFKEHG_01456 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
AFOFKEHG_01457 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
AFOFKEHG_01458 1.2e-181 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
AFOFKEHG_01459 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFOFKEHG_01460 1.77e-32 yqzJ - - - - - - -
AFOFKEHG_01461 3.18e-300 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFOFKEHG_01462 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AFOFKEHG_01463 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AFOFKEHG_01464 3.12e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AFOFKEHG_01465 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
AFOFKEHG_01466 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
AFOFKEHG_01467 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
AFOFKEHG_01468 0.0 rocB - - E - - - arginine degradation protein
AFOFKEHG_01469 2.67e-187 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AFOFKEHG_01470 2.69e-228 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
AFOFKEHG_01471 1.62e-183 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
AFOFKEHG_01472 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
AFOFKEHG_01473 2.69e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
AFOFKEHG_01474 1.28e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFOFKEHG_01476 2.28e-286 yqjV - - G - - - Major Facilitator Superfamily
AFOFKEHG_01478 5.49e-302 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFOFKEHG_01479 3.23e-66 yqiX - - S - - - YolD-like protein
AFOFKEHG_01480 1.29e-111 yqjY - - K ko:K06977 - ko00000 acetyltransferase
AFOFKEHG_01481 2.25e-78 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
AFOFKEHG_01482 2.28e-248 yqkA - - K - - - GrpB protein
AFOFKEHG_01483 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
AFOFKEHG_01484 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
AFOFKEHG_01485 1.38e-223 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
AFOFKEHG_01486 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
AFOFKEHG_01487 5.13e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
AFOFKEHG_01488 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
AFOFKEHG_01489 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
AFOFKEHG_01490 1.98e-278 yqxK - - L - - - DNA helicase
AFOFKEHG_01491 1.29e-76 ansR - - K - - - Transcriptional regulator
AFOFKEHG_01492 3.58e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
AFOFKEHG_01493 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
AFOFKEHG_01494 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
AFOFKEHG_01495 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
AFOFKEHG_01496 3.08e-43 yqkK - - - - - - -
AFOFKEHG_01497 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
AFOFKEHG_01498 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
AFOFKEHG_01499 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
AFOFKEHG_01500 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
AFOFKEHG_01501 2.89e-295 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
AFOFKEHG_01502 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AFOFKEHG_01503 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
AFOFKEHG_01504 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
AFOFKEHG_01505 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
AFOFKEHG_01506 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFOFKEHG_01507 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
AFOFKEHG_01508 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
AFOFKEHG_01509 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
AFOFKEHG_01510 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
AFOFKEHG_01511 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
AFOFKEHG_01512 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
AFOFKEHG_01513 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
AFOFKEHG_01514 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AFOFKEHG_01515 8.93e-192 ypuA - - S - - - Secreted protein
AFOFKEHG_01516 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AFOFKEHG_01519 5.49e-17 - - - S - - - SNARE associated Golgi protein
AFOFKEHG_01520 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
AFOFKEHG_01521 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
AFOFKEHG_01522 5.98e-72 ypuD - - - - - - -
AFOFKEHG_01523 8.41e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AFOFKEHG_01524 7.16e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
AFOFKEHG_01525 1.27e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AFOFKEHG_01526 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
AFOFKEHG_01527 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFOFKEHG_01528 3.18e-123 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
AFOFKEHG_01529 5.42e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AFOFKEHG_01530 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AFOFKEHG_01531 6.13e-128 ypuI - - S - - - Protein of unknown function (DUF3907)
AFOFKEHG_01532 4.11e-273 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
AFOFKEHG_01533 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
AFOFKEHG_01534 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
AFOFKEHG_01535 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
AFOFKEHG_01536 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
AFOFKEHG_01537 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
AFOFKEHG_01538 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
AFOFKEHG_01539 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFOFKEHG_01540 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_01541 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
AFOFKEHG_01542 1.56e-256 rsiX - - - - - - -
AFOFKEHG_01543 2.89e-175 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
AFOFKEHG_01544 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFOFKEHG_01545 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AFOFKEHG_01546 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
AFOFKEHG_01547 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
AFOFKEHG_01548 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
AFOFKEHG_01549 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
AFOFKEHG_01550 5.04e-148 ypbE - - M - - - Lysin motif
AFOFKEHG_01551 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
AFOFKEHG_01552 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
AFOFKEHG_01553 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
AFOFKEHG_01554 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
AFOFKEHG_01555 1.62e-227 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
AFOFKEHG_01556 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
AFOFKEHG_01557 4.88e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
AFOFKEHG_01558 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
AFOFKEHG_01559 4.63e-144 ypfA - - M - - - Flagellar protein YcgR
AFOFKEHG_01560 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
AFOFKEHG_01561 1.73e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
AFOFKEHG_01562 9.5e-263 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
AFOFKEHG_01563 8.41e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AFOFKEHG_01564 1.13e-11 - - - S - - - YpzI-like protein
AFOFKEHG_01565 2.73e-134 yphA - - - - - - -
AFOFKEHG_01566 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
AFOFKEHG_01567 8.69e-40 ypzH - - - - - - -
AFOFKEHG_01568 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
AFOFKEHG_01569 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
AFOFKEHG_01570 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
AFOFKEHG_01571 3.69e-177 yphF - - - - - - -
AFOFKEHG_01572 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AFOFKEHG_01573 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AFOFKEHG_01574 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
AFOFKEHG_01575 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
AFOFKEHG_01576 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
AFOFKEHG_01577 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
AFOFKEHG_01578 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
AFOFKEHG_01579 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
AFOFKEHG_01580 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
AFOFKEHG_01581 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AFOFKEHG_01582 8.48e-265 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AFOFKEHG_01583 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
AFOFKEHG_01584 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AFOFKEHG_01585 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AFOFKEHG_01586 4.18e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
AFOFKEHG_01587 2.82e-153 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
AFOFKEHG_01588 9.33e-295 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AFOFKEHG_01589 3.82e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
AFOFKEHG_01590 4.5e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AFOFKEHG_01591 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
AFOFKEHG_01592 9.91e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
AFOFKEHG_01593 5.27e-299 ypiA - - S - - - COG0457 FOG TPR repeat
AFOFKEHG_01594 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
AFOFKEHG_01595 4.75e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
AFOFKEHG_01596 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
AFOFKEHG_01597 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
AFOFKEHG_01598 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
AFOFKEHG_01599 2.82e-126 ypjA - - S - - - membrane
AFOFKEHG_01600 6.84e-183 ypjB - - S - - - sporulation protein
AFOFKEHG_01601 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
AFOFKEHG_01602 5.72e-71 ypjD - - S - - - Nucleotide pyrophosphohydrolase
AFOFKEHG_01603 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AFOFKEHG_01604 1.52e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
AFOFKEHG_01605 2.69e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
AFOFKEHG_01606 1.04e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
AFOFKEHG_01607 1.41e-283 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AFOFKEHG_01608 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AFOFKEHG_01609 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
AFOFKEHG_01610 1.34e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AFOFKEHG_01611 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AFOFKEHG_01612 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
AFOFKEHG_01613 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
AFOFKEHG_01614 2.27e-103 ypmB - - S - - - protein conserved in bacteria
AFOFKEHG_01615 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
AFOFKEHG_01616 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
AFOFKEHG_01617 2.22e-163 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
AFOFKEHG_01618 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AFOFKEHG_01619 1.6e-118 ypoC - - - - - - -
AFOFKEHG_01620 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
AFOFKEHG_01621 7.54e-149 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AFOFKEHG_01622 4.18e-237 yppC - - S - - - Protein of unknown function (DUF2515)
AFOFKEHG_01625 7.14e-11 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
AFOFKEHG_01626 9.21e-11 - - - S - - - YppF-like protein
AFOFKEHG_01627 1.45e-66 yppG - - S - - - YppG-like protein
AFOFKEHG_01628 5.06e-94 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
AFOFKEHG_01629 5.3e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
AFOFKEHG_01630 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
AFOFKEHG_01631 2.07e-300 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
AFOFKEHG_01632 9.4e-128 ypsA - - S - - - Belongs to the UPF0398 family
AFOFKEHG_01633 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AFOFKEHG_01634 6.82e-275 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
AFOFKEHG_01635 9.72e-66 yqgA - - - - - - -
AFOFKEHG_01637 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
AFOFKEHG_01638 5.4e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFOFKEHG_01639 2.08e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AFOFKEHG_01640 6.14e-235 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
AFOFKEHG_01641 6.95e-238 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
AFOFKEHG_01642 2.53e-133 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
AFOFKEHG_01643 1e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
AFOFKEHG_01644 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AFOFKEHG_01645 1.65e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AFOFKEHG_01646 5.8e-290 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
AFOFKEHG_01647 3.74e-265 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
AFOFKEHG_01648 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
AFOFKEHG_01650 0.0 ypbR - - S - - - Dynamin family
AFOFKEHG_01651 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
AFOFKEHG_01652 1.08e-11 - - - - - - - -
AFOFKEHG_01653 2.26e-213 ypcP - - L - - - 5'3' exonuclease
AFOFKEHG_01654 5.23e-05 - - - - ko:K06429 - ko00000 -
AFOFKEHG_01655 1.6e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
AFOFKEHG_01656 2.4e-138 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AFOFKEHG_01657 4e-163 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
AFOFKEHG_01658 1.54e-37 ypeQ - - S - - - Zinc-finger
AFOFKEHG_01659 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
AFOFKEHG_01660 1.17e-22 degR - - - - - - -
AFOFKEHG_01661 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
AFOFKEHG_01662 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
AFOFKEHG_01663 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AFOFKEHG_01664 1.89e-115 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
AFOFKEHG_01665 2.52e-142 yagB - - S ko:K06950 - ko00000 phosphohydrolase
AFOFKEHG_01666 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
AFOFKEHG_01667 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
AFOFKEHG_01668 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
AFOFKEHG_01669 6.15e-187 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
AFOFKEHG_01670 3.47e-148 ypjP - - S - - - YpjP-like protein
AFOFKEHG_01671 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
AFOFKEHG_01672 7.27e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AFOFKEHG_01673 1.21e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AFOFKEHG_01674 1.71e-145 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
AFOFKEHG_01675 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
AFOFKEHG_01676 1.4e-236 yplP - - K - - - Transcriptional regulator
AFOFKEHG_01677 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AFOFKEHG_01678 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
AFOFKEHG_01679 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
AFOFKEHG_01680 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
AFOFKEHG_01681 6.8e-129 ypmS - - S - - - protein conserved in bacteria
AFOFKEHG_01682 2.13e-40 ypmT - - S - - - Uncharacterized ympT
AFOFKEHG_01683 3.49e-290 mepA - - V - - - MATE efflux family protein
AFOFKEHG_01684 4.14e-94 ypoP - - K - - - transcriptional
AFOFKEHG_01685 8.41e-134 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AFOFKEHG_01686 3.52e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
AFOFKEHG_01687 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
AFOFKEHG_01688 4.17e-282 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
AFOFKEHG_01689 2.95e-240 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
AFOFKEHG_01690 5.57e-86 cgeA - - - ko:K06319 - ko00000 -
AFOFKEHG_01691 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
AFOFKEHG_01692 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
AFOFKEHG_01693 2.06e-186 yiiD - - K ko:K06323 - ko00000 acetyltransferase
AFOFKEHG_01696 0.0 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AFOFKEHG_01698 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
AFOFKEHG_01699 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
AFOFKEHG_01700 1.84e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
AFOFKEHG_01701 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
AFOFKEHG_01702 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
AFOFKEHG_01703 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
AFOFKEHG_01704 3.84e-161 yodN - - - - - - -
AFOFKEHG_01706 5.18e-34 yozD - - S - - - YozD-like protein
AFOFKEHG_01707 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
AFOFKEHG_01708 1.17e-71 yodL - - S - - - YodL-like
AFOFKEHG_01709 2.08e-12 - - - - - - - -
AFOFKEHG_01710 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
AFOFKEHG_01711 1.62e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
AFOFKEHG_01712 2.93e-42 yodI - - - - - - -
AFOFKEHG_01713 6.38e-168 yodH - - Q - - - Methyltransferase
AFOFKEHG_01714 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
AFOFKEHG_01715 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFOFKEHG_01716 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
AFOFKEHG_01717 1.18e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
AFOFKEHG_01718 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
AFOFKEHG_01719 1.92e-140 yodC - - C - - - nitroreductase
AFOFKEHG_01720 1.37e-76 yodB - - K - - - transcriptional
AFOFKEHG_01721 2.05e-86 iolK - - S - - - tautomerase
AFOFKEHG_01722 1.01e-293 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
AFOFKEHG_01723 1.95e-14 - - - - - - - -
AFOFKEHG_01724 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
AFOFKEHG_01725 1.21e-209 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
AFOFKEHG_01726 1.85e-58 - - - - - - - -
AFOFKEHG_01727 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
AFOFKEHG_01728 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
AFOFKEHG_01729 2.49e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
AFOFKEHG_01730 5.06e-314 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
AFOFKEHG_01732 3.69e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AFOFKEHG_01733 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
AFOFKEHG_01734 2.62e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
AFOFKEHG_01735 8.54e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AFOFKEHG_01736 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
AFOFKEHG_01737 0.0 yojO - - P - - - Von Willebrand factor
AFOFKEHG_01738 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
AFOFKEHG_01739 2.13e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
AFOFKEHG_01740 5.48e-213 yocS - - S ko:K03453 - ko00000 -transporter
AFOFKEHG_01741 1.45e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
AFOFKEHG_01742 1.36e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
AFOFKEHG_01743 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
AFOFKEHG_01744 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
AFOFKEHG_01745 1.91e-42 yozC - - - - - - -
AFOFKEHG_01747 2.17e-74 yozO - - S - - - Bacterial PH domain
AFOFKEHG_01748 1.83e-49 yocN - - - - - - -
AFOFKEHG_01749 2.94e-55 yozN - - - - - - -
AFOFKEHG_01750 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
AFOFKEHG_01751 7.29e-46 - - - - - - - -
AFOFKEHG_01752 3.02e-70 yocL - - - - - - -
AFOFKEHG_01753 1.42e-107 yocK - - T - - - general stress protein
AFOFKEHG_01754 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AFOFKEHG_01755 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
AFOFKEHG_01756 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
AFOFKEHG_01757 2.73e-134 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFOFKEHG_01758 1.22e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_01759 2.81e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
AFOFKEHG_01760 3.72e-238 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
AFOFKEHG_01761 1.08e-121 yocC - - - - - - -
AFOFKEHG_01762 2.61e-18 - - - - - - - -
AFOFKEHG_01763 9.79e-130 - - - - - - - -
AFOFKEHG_01764 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
AFOFKEHG_01765 2.89e-151 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
AFOFKEHG_01766 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
AFOFKEHG_01767 1.81e-121 yobW - - - - - - -
AFOFKEHG_01768 2.05e-229 yobV - - K - - - WYL domain
AFOFKEHG_01769 1.55e-114 - - - K - - - Bacterial transcription activator, effector binding domain
AFOFKEHG_01770 1.34e-169 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
AFOFKEHG_01771 9.22e-129 yobS - - K - - - Transcriptional regulator
AFOFKEHG_01772 1.29e-183 - - - J - - - FR47-like protein
AFOFKEHG_01773 5.23e-175 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
AFOFKEHG_01774 2.21e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
AFOFKEHG_01775 0.0 yobO - - M - - - Pectate lyase superfamily protein
AFOFKEHG_01776 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
AFOFKEHG_01777 4.3e-136 yokH - - G - - - SMI1 / KNR4 family
AFOFKEHG_01778 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
AFOFKEHG_01779 6.69e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
AFOFKEHG_01780 3.58e-202 - - - - - - - -
AFOFKEHG_01781 0.0 - - - K - - - Psort location Cytoplasmic, score
AFOFKEHG_01782 2.08e-64 - - - - - - - -
AFOFKEHG_01783 2.05e-51 - - - S - - - YolD-like protein
AFOFKEHG_01784 1.52e-79 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFOFKEHG_01785 6.17e-158 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFOFKEHG_01787 6.23e-267 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
AFOFKEHG_01791 1.36e-08 - - - - - - - -
AFOFKEHG_01792 6.85e-229 - - - - - - - -
AFOFKEHG_01793 1.92e-162 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
AFOFKEHG_01794 1.21e-90 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
AFOFKEHG_01796 3.92e-76 - - - K - - - Helix-turn-helix
AFOFKEHG_01797 6.27e-51 - - - S - - - TM2 domain
AFOFKEHG_01798 1.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
AFOFKEHG_01799 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
AFOFKEHG_01803 9.26e-218 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
AFOFKEHG_01804 3.88e-153 lin0465 - - S - - - DJ-1/PfpI family
AFOFKEHG_01805 6.84e-103 yoaW - - - - - - -
AFOFKEHG_01806 1.11e-202 yoaV - - EG - - - EamA-like transporter family
AFOFKEHG_01807 6.67e-203 yoaU - - K - - - LysR substrate binding domain
AFOFKEHG_01808 6.92e-192 yoaT - - S - - - Protein of unknown function (DUF817)
AFOFKEHG_01809 7.38e-50 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_01810 1.6e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
AFOFKEHG_01811 3.63e-218 yoaR - - V - - - vancomycin resistance protein
AFOFKEHG_01812 2.36e-116 - - - - - - - -
AFOFKEHG_01813 7.38e-88 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
AFOFKEHG_01814 9.48e-188 yoaP - - K - - - YoaP-like
AFOFKEHG_01816 1.95e-296 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
AFOFKEHG_01818 5.08e-171 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
AFOFKEHG_01819 5e-253 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
AFOFKEHG_01820 1.79e-145 yoaK - - S - - - Membrane
AFOFKEHG_01821 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
AFOFKEHG_01822 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
AFOFKEHG_01823 0.0 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
AFOFKEHG_01824 8.23e-62 - - - S - - - Protein of unknown function (DUF4025)
AFOFKEHG_01826 2.08e-44 yoaF - - - - - - -
AFOFKEHG_01827 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AFOFKEHG_01828 1.37e-233 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFOFKEHG_01829 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
AFOFKEHG_01830 1.11e-300 yoaB - - EGP - - - the major facilitator superfamily
AFOFKEHG_01831 5.91e-125 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
AFOFKEHG_01832 1.34e-185 yoxB - - - - - - -
AFOFKEHG_01833 8.39e-57 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
AFOFKEHG_01834 7.94e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
AFOFKEHG_01835 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
AFOFKEHG_01836 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AFOFKEHG_01837 8.13e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AFOFKEHG_01838 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_01839 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
AFOFKEHG_01840 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
AFOFKEHG_01841 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
AFOFKEHG_01842 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_01843 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
AFOFKEHG_01844 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
AFOFKEHG_01845 1.14e-124 - - - L - - - Integrase
AFOFKEHG_01847 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
AFOFKEHG_01848 9.8e-313 yoeA - - V - - - MATE efflux family protein
AFOFKEHG_01849 7.83e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
AFOFKEHG_01850 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
AFOFKEHG_01852 1.14e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
AFOFKEHG_01853 6.68e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
AFOFKEHG_01854 3.06e-88 xkdQ - - G - - - NLP P60 protein
AFOFKEHG_01865 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
AFOFKEHG_01872 9e-276 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
AFOFKEHG_01873 1.13e-218 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
AFOFKEHG_01874 3.26e-50 - - - - - - - -
AFOFKEHG_01875 0.0 lytB - - D - - - Stage II sporulation protein
AFOFKEHG_01876 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
AFOFKEHG_01877 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
AFOFKEHG_01878 3.44e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFOFKEHG_01879 5.68e-279 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
AFOFKEHG_01880 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AFOFKEHG_01881 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
AFOFKEHG_01882 5.79e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
AFOFKEHG_01883 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
AFOFKEHG_01884 3.69e-300 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
AFOFKEHG_01885 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
AFOFKEHG_01886 3.81e-223 yvhJ - - K - - - Transcriptional regulator
AFOFKEHG_01887 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
AFOFKEHG_01888 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
AFOFKEHG_01889 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFOFKEHG_01890 1.77e-198 degV - - S - - - protein conserved in bacteria
AFOFKEHG_01891 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AFOFKEHG_01892 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
AFOFKEHG_01893 9.99e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
AFOFKEHG_01894 1.83e-96 yvyF - - S - - - flagellar protein
AFOFKEHG_01895 1.06e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
AFOFKEHG_01896 3.5e-102 yvyG - - NOU - - - FlgN protein
AFOFKEHG_01897 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
AFOFKEHG_01898 1.97e-199 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
AFOFKEHG_01899 4.19e-93 yviE - - - - - - -
AFOFKEHG_01900 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AFOFKEHG_01901 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AFOFKEHG_01902 8.01e-202 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AFOFKEHG_01903 1.62e-69 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
AFOFKEHG_01904 8.97e-313 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AFOFKEHG_01905 8.56e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
AFOFKEHG_01906 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
AFOFKEHG_01907 9.14e-88 - - - - - - - -
AFOFKEHG_01908 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AFOFKEHG_01909 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AFOFKEHG_01910 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AFOFKEHG_01911 1.86e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
AFOFKEHG_01912 3.78e-74 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
AFOFKEHG_01913 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
AFOFKEHG_01914 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
AFOFKEHG_01915 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
AFOFKEHG_01916 1.38e-73 swrA - - S - - - Swarming motility protein
AFOFKEHG_01917 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFOFKEHG_01918 1.23e-294 yvkA - - P - - - -transporter
AFOFKEHG_01919 4.09e-131 yvkB - - K - - - Transcriptional regulator
AFOFKEHG_01920 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
AFOFKEHG_01921 2.54e-42 csbA - - S - - - protein conserved in bacteria
AFOFKEHG_01922 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AFOFKEHG_01923 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AFOFKEHG_01924 2.57e-104 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AFOFKEHG_01925 2.73e-46 yvkN - - - - - - -
AFOFKEHG_01926 8.09e-65 yvlA - - - - - - -
AFOFKEHG_01927 9.59e-220 yvlB - - S - - - Putative adhesin
AFOFKEHG_01928 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
AFOFKEHG_01929 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
AFOFKEHG_01930 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
AFOFKEHG_01931 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
AFOFKEHG_01932 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
AFOFKEHG_01933 1.61e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
AFOFKEHG_01934 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
AFOFKEHG_01935 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
AFOFKEHG_01936 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
AFOFKEHG_01937 1.39e-171 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AFOFKEHG_01938 6.9e-279 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
AFOFKEHG_01939 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AFOFKEHG_01940 4.33e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AFOFKEHG_01941 5.28e-211 yvoD - - P - - - COG0370 Fe2 transport system protein B
AFOFKEHG_01942 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
AFOFKEHG_01943 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
AFOFKEHG_01944 1.1e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
AFOFKEHG_01945 1.02e-177 yvpB - - NU - - - protein conserved in bacteria
AFOFKEHG_01946 6.64e-279 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AFOFKEHG_01947 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
AFOFKEHG_01948 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AFOFKEHG_01949 2.02e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
AFOFKEHG_01950 1.29e-143 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AFOFKEHG_01951 1.54e-165 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AFOFKEHG_01952 2.29e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
AFOFKEHG_01953 1.7e-142 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
AFOFKEHG_01954 3.22e-97 - - - - - - - -
AFOFKEHG_01955 0.0 - - - - - - - -
AFOFKEHG_01957 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
AFOFKEHG_01958 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
AFOFKEHG_01959 2.18e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
AFOFKEHG_01960 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AFOFKEHG_01961 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
AFOFKEHG_01962 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
AFOFKEHG_01963 3.19e-225 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
AFOFKEHG_01964 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
AFOFKEHG_01965 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
AFOFKEHG_01966 8.02e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
AFOFKEHG_01967 7.95e-45 - - - - - - - -
AFOFKEHG_01968 3.84e-171 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFOFKEHG_01969 9.29e-250 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
AFOFKEHG_01970 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_01971 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
AFOFKEHG_01972 2.82e-235 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFOFKEHG_01973 8.79e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
AFOFKEHG_01974 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
AFOFKEHG_01975 4.54e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
AFOFKEHG_01976 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
AFOFKEHG_01977 2.28e-223 yvdE - - K - - - Transcriptional regulator
AFOFKEHG_01978 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
AFOFKEHG_01979 1.63e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
AFOFKEHG_01980 1.01e-309 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
AFOFKEHG_01981 9.72e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
AFOFKEHG_01982 1.38e-197 malA - - S - - - Protein of unknown function (DUF1189)
AFOFKEHG_01983 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
AFOFKEHG_01984 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
AFOFKEHG_01985 1.01e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
AFOFKEHG_01986 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AFOFKEHG_01988 2.71e-233 - - - S - - - Patatin-like phospholipase
AFOFKEHG_01989 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
AFOFKEHG_01990 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
AFOFKEHG_01991 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
AFOFKEHG_01992 6.31e-68 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
AFOFKEHG_01993 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
AFOFKEHG_01994 0.0 ybeC - - E - - - amino acid
AFOFKEHG_01995 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
AFOFKEHG_01996 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
AFOFKEHG_01997 0.0 pbpE - - V - - - Beta-lactamase
AFOFKEHG_01998 1.69e-160 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
AFOFKEHG_01999 9.03e-96 - - - S - - - Protein of unknown function (DUF3237)
AFOFKEHG_02000 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
AFOFKEHG_02002 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
AFOFKEHG_02003 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
AFOFKEHG_02004 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
AFOFKEHG_02005 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
AFOFKEHG_02006 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
AFOFKEHG_02007 8.11e-284 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
AFOFKEHG_02008 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
AFOFKEHG_02009 2.4e-276 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
AFOFKEHG_02010 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
AFOFKEHG_02011 1e-247 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
AFOFKEHG_02012 9.86e-262 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
AFOFKEHG_02013 1.03e-240 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
AFOFKEHG_02014 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFOFKEHG_02015 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
AFOFKEHG_02016 5.46e-75 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
AFOFKEHG_02017 1.91e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
AFOFKEHG_02018 2.95e-238 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
AFOFKEHG_02019 5.69e-44 yvfG - - S - - - YvfG protein
AFOFKEHG_02020 9.59e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
AFOFKEHG_02021 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
AFOFKEHG_02022 1.18e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
AFOFKEHG_02023 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_02024 2.05e-295 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
AFOFKEHG_02025 1.3e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
AFOFKEHG_02026 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
AFOFKEHG_02027 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
AFOFKEHG_02028 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
AFOFKEHG_02029 8.02e-261 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
AFOFKEHG_02030 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
AFOFKEHG_02031 5.95e-209 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
AFOFKEHG_02032 4.81e-169 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
AFOFKEHG_02033 7.33e-250 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_02034 2.52e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFOFKEHG_02035 2.6e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
AFOFKEHG_02036 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
AFOFKEHG_02037 1.45e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
AFOFKEHG_02038 2.68e-252 - - - S - - - Glycosyl hydrolase
AFOFKEHG_02039 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
AFOFKEHG_02040 3.93e-198 yvbV - - EG - - - EamA-like transporter family
AFOFKEHG_02041 4.9e-206 yvbU - - K - - - Transcriptional regulator
AFOFKEHG_02042 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFOFKEHG_02043 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
AFOFKEHG_02044 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
AFOFKEHG_02045 9.84e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
AFOFKEHG_02046 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AFOFKEHG_02047 3.27e-276 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
AFOFKEHG_02048 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AFOFKEHG_02049 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
AFOFKEHG_02050 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AFOFKEHG_02051 2.4e-106 yvbK - - K - - - acetyltransferase
AFOFKEHG_02052 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
AFOFKEHG_02053 2.38e-158 yvbI - - M - - - Membrane
AFOFKEHG_02054 2.96e-145 yvbH - - S - - - YvbH-like oligomerisation region
AFOFKEHG_02055 1.13e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
AFOFKEHG_02056 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
AFOFKEHG_02057 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
AFOFKEHG_02058 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
AFOFKEHG_02059 2.58e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
AFOFKEHG_02060 1.03e-146 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
AFOFKEHG_02061 9.63e-60 sdpR - - K - - - transcriptional
AFOFKEHG_02062 8.32e-133 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
AFOFKEHG_02064 4.79e-224 - - - - - - - -
AFOFKEHG_02065 2.75e-11 - - - S - - - Sporulation delaying protein SdpA
AFOFKEHG_02066 1.15e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
AFOFKEHG_02067 3.64e-271 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
AFOFKEHG_02068 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
AFOFKEHG_02069 2.89e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
AFOFKEHG_02070 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
AFOFKEHG_02071 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
AFOFKEHG_02072 3.85e-72 yvaP - - K - - - transcriptional
AFOFKEHG_02073 1.19e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
AFOFKEHG_02074 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
AFOFKEHG_02075 3.44e-48 yvzC - - K - - - transcriptional
AFOFKEHG_02076 4.03e-196 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
AFOFKEHG_02077 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
AFOFKEHG_02078 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
AFOFKEHG_02079 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AFOFKEHG_02080 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AFOFKEHG_02082 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
AFOFKEHG_02083 5.77e-127 - - - K - - - Bacterial regulatory proteins, tetR family
AFOFKEHG_02084 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
AFOFKEHG_02085 5.79e-97 yvaD - - S - - - Family of unknown function (DUF5360)
AFOFKEHG_02086 0.0 - - - S - - - Fusaric acid resistance protein-like
AFOFKEHG_02087 2.08e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AFOFKEHG_02088 1.71e-248 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
AFOFKEHG_02089 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
AFOFKEHG_02090 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
AFOFKEHG_02091 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
AFOFKEHG_02092 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
AFOFKEHG_02093 3.45e-137 bdbD - - O - - - Thioredoxin
AFOFKEHG_02094 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
AFOFKEHG_02095 2.34e-139 yvgT - - S - - - membrane
AFOFKEHG_02097 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
AFOFKEHG_02098 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AFOFKEHG_02099 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
AFOFKEHG_02100 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
AFOFKEHG_02101 7.97e-113 yvgO - - - - - - -
AFOFKEHG_02102 6.19e-201 yvgN - - S - - - reductase
AFOFKEHG_02103 1.95e-150 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
AFOFKEHG_02104 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
AFOFKEHG_02105 5.98e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
AFOFKEHG_02106 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
AFOFKEHG_02107 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
AFOFKEHG_02108 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
AFOFKEHG_02109 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
AFOFKEHG_02110 1.09e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
AFOFKEHG_02111 1.21e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFOFKEHG_02112 9.64e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFOFKEHG_02113 1.19e-190 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
AFOFKEHG_02114 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
AFOFKEHG_02115 3.82e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_02116 1.81e-271 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
AFOFKEHG_02117 8.13e-85 yvrL - - S - - - Regulatory protein YrvL
AFOFKEHG_02118 4.39e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
AFOFKEHG_02119 3.46e-26 - - - S - - - YvrJ protein family
AFOFKEHG_02120 6.74e-126 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
AFOFKEHG_02121 5.07e-32 - - - - - - - -
AFOFKEHG_02122 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFOFKEHG_02123 0.0 yvrG - - T - - - Histidine kinase
AFOFKEHG_02124 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
AFOFKEHG_02125 1.23e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
AFOFKEHG_02126 2.98e-218 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
AFOFKEHG_02127 1.56e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFOFKEHG_02128 9.81e-314 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
AFOFKEHG_02129 8.21e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
AFOFKEHG_02130 7.59e-287 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_02131 6.17e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
AFOFKEHG_02132 2.44e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
AFOFKEHG_02133 2.48e-166 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
AFOFKEHG_02134 1.09e-163 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
AFOFKEHG_02135 2.74e-244 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_02136 6.34e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFOFKEHG_02137 1.19e-240 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
AFOFKEHG_02138 9.28e-250 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
AFOFKEHG_02139 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
AFOFKEHG_02140 1.06e-32 - - - S - - - Protein of unknown function (DUF3970)
AFOFKEHG_02141 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
AFOFKEHG_02142 3.06e-204 yuxN - - K - - - Transcriptional regulator
AFOFKEHG_02143 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_02144 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFOFKEHG_02145 9.63e-306 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFOFKEHG_02146 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
AFOFKEHG_02147 6.65e-198 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
AFOFKEHG_02148 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
AFOFKEHG_02149 2.01e-87 - - - S - - - YusW-like protein
AFOFKEHG_02150 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
AFOFKEHG_02151 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
AFOFKEHG_02152 1.52e-206 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
AFOFKEHG_02153 4.48e-67 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
AFOFKEHG_02154 6.81e-82 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
AFOFKEHG_02155 1.76e-86 yusQ - - S - - - Tautomerase enzyme
AFOFKEHG_02156 0.0 yusP - - P - - - Major facilitator superfamily
AFOFKEHG_02157 3.83e-99 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
AFOFKEHG_02158 2.12e-70 yusN - - M - - - Coat F domain
AFOFKEHG_02159 2.23e-54 - - - - - - - -
AFOFKEHG_02160 2.09e-212 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
AFOFKEHG_02161 2.86e-14 - - - S - - - YuzL-like protein
AFOFKEHG_02162 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
AFOFKEHG_02163 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
AFOFKEHG_02164 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
AFOFKEHG_02165 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
AFOFKEHG_02166 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
AFOFKEHG_02167 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
AFOFKEHG_02168 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
AFOFKEHG_02169 5.73e-73 yusE - - CO - - - Thioredoxin
AFOFKEHG_02170 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
AFOFKEHG_02171 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AFOFKEHG_02172 2.64e-125 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
AFOFKEHG_02173 2.91e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
AFOFKEHG_02174 5.44e-81 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AFOFKEHG_02175 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
AFOFKEHG_02176 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
AFOFKEHG_02177 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AFOFKEHG_02178 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
AFOFKEHG_02179 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
AFOFKEHG_02180 1.22e-190 - - - S - - - Pfam:Arm-DNA-bind_4
AFOFKEHG_02181 2.99e-55 - - - E - - - Zn peptidase
AFOFKEHG_02182 2.3e-33 - - - K - - - Helix-turn-helix XRE-family like proteins
AFOFKEHG_02184 1.48e-31 - - - - - - - -
AFOFKEHG_02187 2.16e-32 - - - - - - - -
AFOFKEHG_02188 1.02e-80 - - - S - - - Hypothetical protein (DUF2513)
AFOFKEHG_02189 3.13e-112 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
AFOFKEHG_02192 5.63e-109 - - - L - - - DnaD domain protein
AFOFKEHG_02193 1.57e-16 - - - S - - - Loader and inhibitor of phage G40P
AFOFKEHG_02194 5.4e-211 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 replicative DNA helicase
AFOFKEHG_02195 2.46e-30 - - - - - - - -
AFOFKEHG_02196 1.66e-175 - - - - - - - -
AFOFKEHG_02199 4.31e-37 - - - L ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
AFOFKEHG_02201 2.2e-182 - - - S - - - Phage Terminase
AFOFKEHG_02202 4.15e-129 - - - S - - - Phage portal protein
AFOFKEHG_02203 9.76e-61 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
AFOFKEHG_02204 1.38e-111 - - - S - - - Phage capsid family
AFOFKEHG_02205 7.25e-16 - - - S - - - Phage gp6-like head-tail connector protein
AFOFKEHG_02207 5.86e-14 - - - S - - - TIGRFAM phage protein, HK97 gp10 family
AFOFKEHG_02209 9.51e-69 - - - S - - - phage major tail protein, phi13 family
AFOFKEHG_02210 0.000103 - - - - - - - -
AFOFKEHG_02211 1.36e-174 - - - D - - - phage tail tape measure protein
AFOFKEHG_02213 4.11e-132 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
AFOFKEHG_02214 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
AFOFKEHG_02215 2.12e-106 - - - - - - - -
AFOFKEHG_02217 2.88e-122 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
AFOFKEHG_02218 4.4e-75 - - - S - - - Bacteriophage holin family
AFOFKEHG_02219 5.85e-164 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
AFOFKEHG_02220 4.33e-109 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
AFOFKEHG_02221 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
AFOFKEHG_02222 7.82e-137 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
AFOFKEHG_02226 8.23e-38 - - - - - - - -
AFOFKEHG_02227 2.14e-87 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFOFKEHG_02228 3.35e-56 - - - - - - - -
AFOFKEHG_02230 1.42e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
AFOFKEHG_02231 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
AFOFKEHG_02232 1.29e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
AFOFKEHG_02233 2.46e-308 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
AFOFKEHG_02234 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AFOFKEHG_02235 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
AFOFKEHG_02236 3.9e-208 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
AFOFKEHG_02237 7.46e-176 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
AFOFKEHG_02238 6.95e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
AFOFKEHG_02239 6.53e-218 bsn - - L - - - Ribonuclease
AFOFKEHG_02240 4.9e-303 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
AFOFKEHG_02241 8.51e-306 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
AFOFKEHG_02243 5.12e-243 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AFOFKEHG_02244 2.62e-144 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
AFOFKEHG_02245 4.85e-194 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
AFOFKEHG_02246 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
AFOFKEHG_02247 2.42e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
AFOFKEHG_02248 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
AFOFKEHG_02249 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
AFOFKEHG_02250 7.82e-284 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
AFOFKEHG_02251 3.65e-292 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
AFOFKEHG_02252 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
AFOFKEHG_02253 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
AFOFKEHG_02254 1.07e-79 yunG - - - - - - -
AFOFKEHG_02255 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
AFOFKEHG_02256 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
AFOFKEHG_02257 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
AFOFKEHG_02258 3.41e-65 yunC - - S - - - Domain of unknown function (DUF1805)
AFOFKEHG_02259 2.46e-171 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
AFOFKEHG_02260 3.11e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
AFOFKEHG_02261 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AFOFKEHG_02262 5.47e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
AFOFKEHG_02263 3.2e-63 yutD - - S - - - protein conserved in bacteria
AFOFKEHG_02264 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
AFOFKEHG_02265 2.49e-181 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AFOFKEHG_02266 3.21e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
AFOFKEHG_02267 2.68e-254 yutH - - S - - - Spore coat protein
AFOFKEHG_02268 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
AFOFKEHG_02269 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AFOFKEHG_02270 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AFOFKEHG_02271 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
AFOFKEHG_02272 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
AFOFKEHG_02273 5.44e-74 yuzD - - S - - - protein conserved in bacteria
AFOFKEHG_02274 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
AFOFKEHG_02275 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
AFOFKEHG_02276 8.88e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AFOFKEHG_02277 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AFOFKEHG_02278 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
AFOFKEHG_02279 6.88e-116 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFOFKEHG_02280 5.51e-147 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
AFOFKEHG_02281 6.4e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AFOFKEHG_02283 1.92e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
AFOFKEHG_02284 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
AFOFKEHG_02285 1.14e-45 yuiB - - S - - - Putative membrane protein
AFOFKEHG_02286 2.69e-150 yuiC - - S - - - protein conserved in bacteria
AFOFKEHG_02287 7.09e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
AFOFKEHG_02288 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AFOFKEHG_02289 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
AFOFKEHG_02290 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
AFOFKEHG_02291 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
AFOFKEHG_02292 1.55e-213 eSD - - S ko:K07017 - ko00000 Putative esterase
AFOFKEHG_02293 1.43e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
AFOFKEHG_02294 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
AFOFKEHG_02295 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
AFOFKEHG_02296 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
AFOFKEHG_02297 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFOFKEHG_02298 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
AFOFKEHG_02299 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
AFOFKEHG_02300 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
AFOFKEHG_02301 2.96e-292 yukF - - QT - - - Transcriptional regulator
AFOFKEHG_02302 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
AFOFKEHG_02303 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
AFOFKEHG_02304 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
AFOFKEHG_02305 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
AFOFKEHG_02306 0.0 yueB - - S - - - type VII secretion protein EsaA
AFOFKEHG_02307 1.46e-95 yueC - - S - - - Family of unknown function (DUF5383)
AFOFKEHG_02308 6.83e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFOFKEHG_02309 6.39e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
AFOFKEHG_02310 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
AFOFKEHG_02311 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
AFOFKEHG_02312 2.24e-243 yueF - - S - - - transporter activity
AFOFKEHG_02313 1.19e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
AFOFKEHG_02314 1.63e-52 yueH - - S - - - YueH-like protein
AFOFKEHG_02315 5.17e-86 - - - S - - - Protein of unknown function (DUF1694)
AFOFKEHG_02316 3.27e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
AFOFKEHG_02317 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AFOFKEHG_02318 1.39e-296 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
AFOFKEHG_02319 8.73e-09 yuzC - - - - - - -
AFOFKEHG_02320 6.29e-10 - - - S - - - DegQ (SacQ) family
AFOFKEHG_02321 7.01e-183 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
AFOFKEHG_02323 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_02324 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFOFKEHG_02325 3.18e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
AFOFKEHG_02326 5.74e-77 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
AFOFKEHG_02327 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFOFKEHG_02328 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFOFKEHG_02329 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFOFKEHG_02330 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFOFKEHG_02331 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFOFKEHG_02332 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
AFOFKEHG_02333 7.06e-22 - - - - - - - -
AFOFKEHG_02334 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
AFOFKEHG_02335 1.47e-216 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
AFOFKEHG_02336 1.57e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
AFOFKEHG_02337 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_02338 9.13e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
AFOFKEHG_02339 1.14e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
AFOFKEHG_02340 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
AFOFKEHG_02341 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
AFOFKEHG_02342 3.31e-98 yuxK - - S - - - protein conserved in bacteria
AFOFKEHG_02343 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
AFOFKEHG_02344 1.96e-245 yuxJ - - EGP - - - Major facilitator superfamily
AFOFKEHG_02346 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
AFOFKEHG_02347 4.3e-92 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
AFOFKEHG_02348 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_02349 2.09e-289 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
AFOFKEHG_02350 6.7e-56 yugE - - S - - - Domain of unknown function (DUF1871)
AFOFKEHG_02351 1.2e-201 yugF - - I - - - Hydrolase
AFOFKEHG_02352 6.74e-112 alaR - - K - - - Transcriptional regulator
AFOFKEHG_02353 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
AFOFKEHG_02354 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
AFOFKEHG_02355 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
AFOFKEHG_02356 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
AFOFKEHG_02357 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
AFOFKEHG_02358 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
AFOFKEHG_02360 4.22e-95 yugN - - S - - - YugN-like family
AFOFKEHG_02361 3.56e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
AFOFKEHG_02362 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
AFOFKEHG_02363 2.16e-48 - - - - - - - -
AFOFKEHG_02364 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
AFOFKEHG_02365 2.52e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
AFOFKEHG_02366 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
AFOFKEHG_02367 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
AFOFKEHG_02368 2.04e-47 - - - - - - - -
AFOFKEHG_02369 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
AFOFKEHG_02370 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
AFOFKEHG_02371 2.29e-295 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
AFOFKEHG_02372 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
AFOFKEHG_02373 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
AFOFKEHG_02375 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
AFOFKEHG_02376 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
AFOFKEHG_02377 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
AFOFKEHG_02378 4.94e-73 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
AFOFKEHG_02379 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
AFOFKEHG_02380 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
AFOFKEHG_02381 1.73e-252 yubA - - S - - - transporter activity
AFOFKEHG_02382 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
AFOFKEHG_02384 3.25e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
AFOFKEHG_02385 0.0 yubD - - P - - - Major Facilitator Superfamily
AFOFKEHG_02386 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AFOFKEHG_02387 3.31e-52 yubF - - S - - - yiaA/B two helix domain
AFOFKEHG_02388 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
AFOFKEHG_02389 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
AFOFKEHG_02390 5.83e-118 yuaB - - - - - - -
AFOFKEHG_02391 1.68e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
AFOFKEHG_02392 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
AFOFKEHG_02393 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
AFOFKEHG_02394 1.42e-137 yuaD - - - - - - -
AFOFKEHG_02395 1.95e-109 yuaE - - S - - - DinB superfamily
AFOFKEHG_02396 4.06e-110 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
AFOFKEHG_02397 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
AFOFKEHG_02398 1.2e-122 - - - M - - - FR47-like protein
AFOFKEHG_02399 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
AFOFKEHG_02400 0.0 xkdO - - L - - - Transglycosylase SLT domain
AFOFKEHG_02401 9.14e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
AFOFKEHG_02403 4.23e-99 xkdM - - S - - - Phage tail tube protein
AFOFKEHG_02404 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
AFOFKEHG_02405 2.52e-36 - - - - - - - -
AFOFKEHG_02406 3.24e-102 yqbJ - - - - - - -
AFOFKEHG_02407 7.59e-123 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
AFOFKEHG_02408 7.08e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
AFOFKEHG_02409 7.09e-88 - - - S - - - Protein of unknown function (DUF3199)
AFOFKEHG_02410 2.47e-68 - - - S - - - YqbF, hypothetical protein domain
AFOFKEHG_02411 9.21e-216 xkdG - - S - - - Phage capsid family
AFOFKEHG_02412 5.46e-186 yqbD - - L - - - Putative phage serine protease XkdF
AFOFKEHG_02413 2.13e-149 - - - - - - - -
AFOFKEHG_02414 4.07e-216 - - - S - - - Phage Mu protein F like protein
AFOFKEHG_02415 0.0 yqbA - - S - - - portal protein
AFOFKEHG_02416 0.0 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
AFOFKEHG_02417 2.02e-158 yqaS - - L - - - DNA packaging
AFOFKEHG_02419 1.58e-105 yqaQ - - L - - - Transposase
AFOFKEHG_02420 7.56e-214 - - - - - - - -
AFOFKEHG_02421 2.49e-43 yqaO - - S - - - Phage-like element PBSX protein XtrA
AFOFKEHG_02422 1.38e-97 rusA - - L - - - Endodeoxyribonuclease RusA
AFOFKEHG_02424 4.9e-214 yqaM - - L - - - IstB-like ATP binding protein
AFOFKEHG_02425 1.92e-158 yqaL - - L - - - DnaD domain protein
AFOFKEHG_02426 1.1e-198 recT - - L ko:K07455 - ko00000,ko03400 RecT family
AFOFKEHG_02427 9.38e-229 yqaJ - - L - - - YqaJ-like viral recombinase domain
AFOFKEHG_02431 1.27e-134 - - - - - - - -
AFOFKEHG_02433 3.43e-49 - - - K - - - Helix-turn-helix XRE-family like proteins
AFOFKEHG_02434 1.25e-74 - - - K - - - sequence-specific DNA binding
AFOFKEHG_02436 8.73e-132 yqaC - - F - - - adenylate kinase activity
AFOFKEHG_02437 2.25e-131 xkdA - - E - - - IrrE N-terminal-like domain
AFOFKEHG_02438 1.42e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFOFKEHG_02439 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
AFOFKEHG_02440 7.32e-306 yrkQ - - T - - - Histidine kinase
AFOFKEHG_02441 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
AFOFKEHG_02442 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
AFOFKEHG_02443 1.33e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
AFOFKEHG_02444 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
AFOFKEHG_02445 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
AFOFKEHG_02446 1.21e-170 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
AFOFKEHG_02447 1.11e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
AFOFKEHG_02448 7e-272 yrkH - - P - - - Rhodanese Homology Domain
AFOFKEHG_02449 2.04e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
AFOFKEHG_02450 2.38e-109 yrkE - - O - - - DsrE/DsrF/DrsH-like family
AFOFKEHG_02451 4.38e-52 yrkD - - S - - - protein conserved in bacteria
AFOFKEHG_02452 3.81e-139 yrkC - - G - - - Cupin domain
AFOFKEHG_02454 2.15e-195 bltR - - K - - - helix_turn_helix, mercury resistance
AFOFKEHG_02455 3.76e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_02456 3.73e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
AFOFKEHG_02457 1.58e-301 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
AFOFKEHG_02458 7.28e-25 - - - S - - - YrzO-like protein
AFOFKEHG_02459 1.53e-219 yrdR - - EG - - - EamA-like transporter family
AFOFKEHG_02460 1.4e-203 - - - K - - - Transcriptional regulator
AFOFKEHG_02461 2.58e-255 trkA - - P ko:K07222 - ko00000 Oxidoreductase
AFOFKEHG_02462 2.26e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
AFOFKEHG_02463 1.75e-87 yodA - - S - - - tautomerase
AFOFKEHG_02464 2e-207 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
AFOFKEHG_02466 7.09e-292 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
AFOFKEHG_02467 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
AFOFKEHG_02468 9.34e-176 azlC - - E - - - AzlC protein
AFOFKEHG_02469 1.44e-104 bkdR - - K - - - helix_turn_helix ASNC type
AFOFKEHG_02470 1.07e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
AFOFKEHG_02471 1.75e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
AFOFKEHG_02472 7.37e-133 yrdC - - Q - - - Isochorismatase family
AFOFKEHG_02473 2.28e-75 - - - S - - - Protein of unknown function (DUF2568)
AFOFKEHG_02474 1.47e-120 yrdA - - S - - - DinB family
AFOFKEHG_02475 2.66e-215 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
AFOFKEHG_02476 3.79e-249 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
AFOFKEHG_02477 8.73e-191 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
AFOFKEHG_02478 5.87e-163 yrpD - - S - - - Domain of unknown function, YrpD
AFOFKEHG_02480 9.28e-170 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
AFOFKEHG_02481 9.08e-124 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
AFOFKEHG_02482 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
AFOFKEHG_02483 9.19e-287 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
AFOFKEHG_02484 2.97e-210 yraN - - K - - - Transcriptional regulator
AFOFKEHG_02485 5.95e-263 yraM - - S - - - PrpF protein
AFOFKEHG_02487 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
AFOFKEHG_02488 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFOFKEHG_02489 4.9e-200 - - - S - - - Alpha beta hydrolase
AFOFKEHG_02490 6.61e-80 - - - T - - - sh3 domain protein
AFOFKEHG_02491 2.92e-81 - - - T - - - sh3 domain protein
AFOFKEHG_02492 6.62e-87 - - - E - - - Glyoxalase-like domain
AFOFKEHG_02493 4.19e-50 yraG - - - ko:K06440 - ko00000 -
AFOFKEHG_02494 9.61e-84 yraF - - M - - - Spore coat protein
AFOFKEHG_02495 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
AFOFKEHG_02496 1.05e-36 yraE - - - ko:K06440 - ko00000 -
AFOFKEHG_02497 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
AFOFKEHG_02498 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
AFOFKEHG_02499 3.03e-40 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
AFOFKEHG_02500 4.3e-256 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
AFOFKEHG_02501 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
AFOFKEHG_02502 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
AFOFKEHG_02503 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
AFOFKEHG_02504 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
AFOFKEHG_02505 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
AFOFKEHG_02506 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
AFOFKEHG_02507 0.0 levR - - K - - - PTS system fructose IIA component
AFOFKEHG_02508 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
AFOFKEHG_02509 5.63e-137 yrhP - - E - - - LysE type translocator
AFOFKEHG_02510 2.81e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
AFOFKEHG_02511 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
AFOFKEHG_02512 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
AFOFKEHG_02513 0.0 oatA - - I - - - Acyltransferase family
AFOFKEHG_02514 7.65e-62 yrhK - - S - - - YrhK-like protein
AFOFKEHG_02515 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
AFOFKEHG_02516 1.12e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
AFOFKEHG_02517 1.1e-126 yrhH - - Q - - - methyltransferase
AFOFKEHG_02518 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
AFOFKEHG_02520 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
AFOFKEHG_02521 1.08e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
AFOFKEHG_02522 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
AFOFKEHG_02523 4.26e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
AFOFKEHG_02524 6.93e-49 yrhC - - S - - - YrhC-like protein
AFOFKEHG_02525 4.24e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
AFOFKEHG_02526 7.04e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
AFOFKEHG_02527 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AFOFKEHG_02528 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
AFOFKEHG_02529 8.52e-37 yrzA - - S - - - Protein of unknown function (DUF2536)
AFOFKEHG_02530 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
AFOFKEHG_02531 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
AFOFKEHG_02532 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AFOFKEHG_02533 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
AFOFKEHG_02534 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
AFOFKEHG_02535 6.57e-224 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
AFOFKEHG_02536 1.7e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
AFOFKEHG_02537 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AFOFKEHG_02538 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
AFOFKEHG_02539 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AFOFKEHG_02540 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
AFOFKEHG_02541 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AFOFKEHG_02542 6.2e-242 yrrI - - S - - - AI-2E family transporter
AFOFKEHG_02543 7.7e-169 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
AFOFKEHG_02544 7.39e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
AFOFKEHG_02545 2.28e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
AFOFKEHG_02546 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
AFOFKEHG_02547 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
AFOFKEHG_02548 8.4e-42 yrzR - - - - - - -
AFOFKEHG_02549 9.73e-106 yrrD - - S - - - protein conserved in bacteria
AFOFKEHG_02550 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AFOFKEHG_02551 3.89e-20 yrrB - - S - - - COG0457 FOG TPR repeat
AFOFKEHG_02552 3.97e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AFOFKEHG_02553 1.87e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
AFOFKEHG_02554 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_02555 2.33e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
AFOFKEHG_02556 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
AFOFKEHG_02557 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AFOFKEHG_02558 1.27e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
AFOFKEHG_02560 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
AFOFKEHG_02561 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AFOFKEHG_02562 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AFOFKEHG_02563 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AFOFKEHG_02564 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
AFOFKEHG_02565 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
AFOFKEHG_02566 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
AFOFKEHG_02567 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AFOFKEHG_02568 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
AFOFKEHG_02569 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFOFKEHG_02570 5.83e-143 yrbG - - S - - - membrane
AFOFKEHG_02571 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
AFOFKEHG_02572 1.24e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
AFOFKEHG_02573 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AFOFKEHG_02574 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AFOFKEHG_02575 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
AFOFKEHG_02576 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AFOFKEHG_02577 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AFOFKEHG_02578 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
AFOFKEHG_02579 0.0 csbX - - EGP - - - the major facilitator superfamily
AFOFKEHG_02580 7.93e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
AFOFKEHG_02581 2.32e-152 yrzF - - T - - - serine threonine protein kinase
AFOFKEHG_02583 2.32e-45 - - - S - - - Family of unknown function (DUF5412)
AFOFKEHG_02585 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
AFOFKEHG_02586 8.63e-165 yebC - - K - - - transcriptional regulatory protein
AFOFKEHG_02587 7.28e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
AFOFKEHG_02588 1.71e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
AFOFKEHG_02589 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AFOFKEHG_02590 8.17e-208 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
AFOFKEHG_02591 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
AFOFKEHG_02592 2.43e-283 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
AFOFKEHG_02593 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
AFOFKEHG_02594 4.1e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
AFOFKEHG_02595 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
AFOFKEHG_02596 5.59e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFOFKEHG_02597 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
AFOFKEHG_02598 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
AFOFKEHG_02599 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
AFOFKEHG_02600 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
AFOFKEHG_02601 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
AFOFKEHG_02602 1.83e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
AFOFKEHG_02603 6.84e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
AFOFKEHG_02604 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
AFOFKEHG_02605 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
AFOFKEHG_02606 6.39e-201 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
AFOFKEHG_02607 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
AFOFKEHG_02608 1.97e-161 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
AFOFKEHG_02609 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
AFOFKEHG_02610 3.36e-208 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
AFOFKEHG_02611 4.61e-107 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
AFOFKEHG_02612 5.8e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
AFOFKEHG_02613 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AFOFKEHG_02614 1.53e-35 - - - - - - - -
AFOFKEHG_02615 2.91e-253 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AFOFKEHG_02616 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
AFOFKEHG_02617 1.05e-313 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
AFOFKEHG_02618 6.39e-234 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
AFOFKEHG_02619 1.57e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
AFOFKEHG_02620 2.66e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
AFOFKEHG_02621 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
AFOFKEHG_02622 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AFOFKEHG_02623 8.23e-117 ysxD - - - - - - -
AFOFKEHG_02624 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
AFOFKEHG_02625 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AFOFKEHG_02626 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
AFOFKEHG_02627 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AFOFKEHG_02628 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AFOFKEHG_02629 2.73e-240 ysoA - - H - - - Tetratricopeptide repeat
AFOFKEHG_02630 5.35e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AFOFKEHG_02631 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AFOFKEHG_02632 1.06e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
AFOFKEHG_02633 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AFOFKEHG_02634 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AFOFKEHG_02635 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
AFOFKEHG_02636 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
AFOFKEHG_02638 3.32e-107 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
AFOFKEHG_02639 1.01e-184 ysnF - - S - - - protein conserved in bacteria
AFOFKEHG_02641 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
AFOFKEHG_02642 1.06e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AFOFKEHG_02643 2.04e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AFOFKEHG_02644 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
AFOFKEHG_02645 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
AFOFKEHG_02646 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
AFOFKEHG_02647 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_02648 1.79e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
AFOFKEHG_02649 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
AFOFKEHG_02650 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
AFOFKEHG_02651 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
AFOFKEHG_02652 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
AFOFKEHG_02653 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
AFOFKEHG_02654 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AFOFKEHG_02655 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
AFOFKEHG_02656 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
AFOFKEHG_02658 1.23e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
AFOFKEHG_02659 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
AFOFKEHG_02660 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
AFOFKEHG_02661 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_02662 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
AFOFKEHG_02663 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
AFOFKEHG_02664 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AFOFKEHG_02665 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
AFOFKEHG_02666 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
AFOFKEHG_02667 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AFOFKEHG_02668 1.37e-218 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFOFKEHG_02669 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFOFKEHG_02670 7.36e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AFOFKEHG_02671 5.19e-170 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFOFKEHG_02672 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
AFOFKEHG_02673 6.71e-265 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
AFOFKEHG_02674 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
AFOFKEHG_02675 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
AFOFKEHG_02676 8.17e-52 ysfE 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
AFOFKEHG_02678 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
AFOFKEHG_02679 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
AFOFKEHG_02680 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
AFOFKEHG_02681 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
AFOFKEHG_02682 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
AFOFKEHG_02683 1.47e-288 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
AFOFKEHG_02684 1.05e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
AFOFKEHG_02685 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
AFOFKEHG_02686 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
AFOFKEHG_02687 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
AFOFKEHG_02688 4.21e-243 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
AFOFKEHG_02689 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
AFOFKEHG_02690 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
AFOFKEHG_02691 1.27e-59 ysdA - - S - - - Membrane
AFOFKEHG_02692 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AFOFKEHG_02693 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
AFOFKEHG_02694 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AFOFKEHG_02696 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
AFOFKEHG_02697 2.08e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
AFOFKEHG_02698 2.9e-168 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
AFOFKEHG_02699 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_02700 2.07e-191 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
AFOFKEHG_02701 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AFOFKEHG_02702 5.98e-206 ytxC - - S - - - YtxC-like family
AFOFKEHG_02703 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
AFOFKEHG_02704 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
AFOFKEHG_02705 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
AFOFKEHG_02706 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AFOFKEHG_02707 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AFOFKEHG_02708 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AFOFKEHG_02709 9.85e-88 ytcD - - K - - - Transcriptional regulator
AFOFKEHG_02710 5.44e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
AFOFKEHG_02711 4.54e-205 ytbE - - S - - - reductase
AFOFKEHG_02712 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AFOFKEHG_02713 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
AFOFKEHG_02714 7e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AFOFKEHG_02715 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AFOFKEHG_02716 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
AFOFKEHG_02717 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFOFKEHG_02718 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
AFOFKEHG_02719 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
AFOFKEHG_02720 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
AFOFKEHG_02721 9.38e-95 ytwI - - S - - - membrane
AFOFKEHG_02722 5.51e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
AFOFKEHG_02723 5.68e-83 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
AFOFKEHG_02724 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
AFOFKEHG_02725 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AFOFKEHG_02726 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
AFOFKEHG_02727 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AFOFKEHG_02728 6.01e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
AFOFKEHG_02729 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
AFOFKEHG_02730 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
AFOFKEHG_02731 5.12e-112 ytrI - - - - - - -
AFOFKEHG_02732 1.15e-39 - - - - - - - -
AFOFKEHG_02733 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
AFOFKEHG_02734 2.15e-63 ytpI - - S - - - YtpI-like protein
AFOFKEHG_02735 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
AFOFKEHG_02736 2.24e-206 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
AFOFKEHG_02737 2.09e-306 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
AFOFKEHG_02738 1.69e-166 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
AFOFKEHG_02739 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFOFKEHG_02740 5.26e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
AFOFKEHG_02741 1.52e-237 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFOFKEHG_02742 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
AFOFKEHG_02743 4.08e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AFOFKEHG_02744 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AFOFKEHG_02745 4.01e-194 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
AFOFKEHG_02746 3.18e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
AFOFKEHG_02747 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
AFOFKEHG_02748 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
AFOFKEHG_02749 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
AFOFKEHG_02750 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFOFKEHG_02752 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
AFOFKEHG_02753 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
AFOFKEHG_02754 8.14e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
AFOFKEHG_02755 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AFOFKEHG_02756 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
AFOFKEHG_02757 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AFOFKEHG_02758 2.24e-96 ytfJ - - S - - - Sporulation protein YtfJ
AFOFKEHG_02759 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
AFOFKEHG_02760 7.05e-113 yteJ - - S - - - RDD family
AFOFKEHG_02761 6.13e-233 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
AFOFKEHG_02762 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AFOFKEHG_02763 0.0 ytcJ - - S - - - amidohydrolase
AFOFKEHG_02764 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
AFOFKEHG_02765 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
AFOFKEHG_02766 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AFOFKEHG_02767 4.75e-267 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
AFOFKEHG_02768 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
AFOFKEHG_02769 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AFOFKEHG_02770 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
AFOFKEHG_02771 2.94e-142 yttP - - K - - - Transcriptional regulator
AFOFKEHG_02772 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
AFOFKEHG_02773 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
AFOFKEHG_02774 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AFOFKEHG_02776 6.47e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AFOFKEHG_02777 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
AFOFKEHG_02778 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
AFOFKEHG_02779 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
AFOFKEHG_02780 6.51e-293 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
AFOFKEHG_02781 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
AFOFKEHG_02782 1.96e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
AFOFKEHG_02783 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
AFOFKEHG_02784 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
AFOFKEHG_02785 1.9e-72 ytxJ - - O - - - Protein of unknown function (DUF2847)
AFOFKEHG_02786 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
AFOFKEHG_02787 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AFOFKEHG_02788 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
AFOFKEHG_02789 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
AFOFKEHG_02790 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFOFKEHG_02791 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
AFOFKEHG_02792 3.17e-75 ytpP - - CO - - - Thioredoxin
AFOFKEHG_02793 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
AFOFKEHG_02794 2.24e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
AFOFKEHG_02795 4.06e-68 ytzB - - S - - - small secreted protein
AFOFKEHG_02796 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
AFOFKEHG_02797 2.16e-193 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
AFOFKEHG_02798 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AFOFKEHG_02799 9.51e-61 ytzH - - S - - - YtzH-like protein
AFOFKEHG_02800 3.02e-192 ytmP - - M - - - Phosphotransferase
AFOFKEHG_02801 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
AFOFKEHG_02802 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
AFOFKEHG_02803 4.92e-212 ytlQ - - - - - - -
AFOFKEHG_02804 7.71e-133 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AFOFKEHG_02805 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
AFOFKEHG_02806 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
AFOFKEHG_02807 1.73e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
AFOFKEHG_02808 8.45e-263 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
AFOFKEHG_02809 2.4e-169 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
AFOFKEHG_02810 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
AFOFKEHG_02811 9.04e-171 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
AFOFKEHG_02812 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFOFKEHG_02813 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
AFOFKEHG_02814 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
AFOFKEHG_02815 2.14e-36 yteV - - S - - - Sporulation protein Cse60
AFOFKEHG_02816 1.97e-152 yteU - - S - - - Integral membrane protein
AFOFKEHG_02817 6.02e-315 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
AFOFKEHG_02818 4.78e-94 yteS - - G - - - transport
AFOFKEHG_02819 1.88e-275 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
AFOFKEHG_02820 2.27e-221 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
AFOFKEHG_02821 0.0 ytdP - - K - - - Transcriptional regulator
AFOFKEHG_02822 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
AFOFKEHG_02823 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
AFOFKEHG_02824 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
AFOFKEHG_02825 4.38e-286 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
AFOFKEHG_02826 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AFOFKEHG_02827 1.28e-157 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AFOFKEHG_02828 3.15e-276 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
AFOFKEHG_02829 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
AFOFKEHG_02830 3.72e-191 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
AFOFKEHG_02831 2.66e-218 - - - S - - - Acetyl xylan esterase (AXE1)
AFOFKEHG_02832 3.75e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_02833 2.58e-312 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
AFOFKEHG_02834 4.75e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
AFOFKEHG_02835 1.48e-183 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
AFOFKEHG_02836 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
AFOFKEHG_02837 1.22e-68 ytwF - - P - - - Sulfurtransferase
AFOFKEHG_02838 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
AFOFKEHG_02839 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
AFOFKEHG_02840 5.43e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
AFOFKEHG_02841 2.98e-269 yttB - - EGP - - - Major facilitator superfamily
AFOFKEHG_02842 2.02e-78 yttA - - S - - - Pfam Transposase IS66
AFOFKEHG_02843 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
AFOFKEHG_02844 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_02845 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
AFOFKEHG_02846 1.57e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFOFKEHG_02847 6.91e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
AFOFKEHG_02848 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_02849 5.96e-180 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
AFOFKEHG_02850 1.72e-192 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
AFOFKEHG_02851 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_02852 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
AFOFKEHG_02854 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
AFOFKEHG_02855 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
AFOFKEHG_02856 1.59e-135 ytqB - - J - - - Putative rRNA methylase
AFOFKEHG_02857 2.29e-274 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
AFOFKEHG_02858 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
AFOFKEHG_02859 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AFOFKEHG_02860 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
AFOFKEHG_02861 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
AFOFKEHG_02862 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AFOFKEHG_02863 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AFOFKEHG_02864 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
AFOFKEHG_02865 6.67e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
AFOFKEHG_02866 2.77e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
AFOFKEHG_02867 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
AFOFKEHG_02868 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
AFOFKEHG_02869 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
AFOFKEHG_02870 1.59e-81 ytkC - - S - - - Bacteriophage holin family
AFOFKEHG_02871 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
AFOFKEHG_02873 8.26e-96 ytkA - - S - - - YtkA-like
AFOFKEHG_02874 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AFOFKEHG_02875 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
AFOFKEHG_02876 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
AFOFKEHG_02877 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
AFOFKEHG_02878 2.96e-241 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
AFOFKEHG_02879 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
AFOFKEHG_02880 9.65e-194 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
AFOFKEHG_02881 1.64e-299 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
AFOFKEHG_02882 1.83e-180 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
AFOFKEHG_02883 1.13e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
AFOFKEHG_02884 7.07e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
AFOFKEHG_02885 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
AFOFKEHG_02886 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AFOFKEHG_02887 5.09e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
AFOFKEHG_02888 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AFOFKEHG_02889 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
AFOFKEHG_02890 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
AFOFKEHG_02891 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
AFOFKEHG_02892 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AFOFKEHG_02893 7.74e-231 ytcB - - M - - - NAD-dependent epimerase dehydratase
AFOFKEHG_02894 3.7e-300 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
AFOFKEHG_02896 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
AFOFKEHG_02897 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
AFOFKEHG_02898 9.43e-263 cotI - - S ko:K06331 - ko00000 Spore coat protein
AFOFKEHG_02899 1.97e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
AFOFKEHG_02900 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AFOFKEHG_02901 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
AFOFKEHG_02902 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
AFOFKEHG_02903 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AFOFKEHG_02904 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AFOFKEHG_02913 6.67e-301 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
AFOFKEHG_02914 2.13e-101 yffB - - K - - - Transcriptional regulator
AFOFKEHG_02915 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
AFOFKEHG_02916 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
AFOFKEHG_02917 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
AFOFKEHG_02918 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
AFOFKEHG_02919 3.7e-203 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
AFOFKEHG_02920 4.34e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
AFOFKEHG_02921 7.53e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_02922 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
AFOFKEHG_02923 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
AFOFKEHG_02924 3.52e-178 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
AFOFKEHG_02925 1.82e-296 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
AFOFKEHG_02926 7.55e-266 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
AFOFKEHG_02927 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
AFOFKEHG_02928 5.43e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFOFKEHG_02929 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
AFOFKEHG_02930 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
AFOFKEHG_02931 7.68e-275 ywfA - - EGP - - - -transporter
AFOFKEHG_02932 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
AFOFKEHG_02933 0.0 rocB - - E - - - arginine degradation protein
AFOFKEHG_02934 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
AFOFKEHG_02935 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
AFOFKEHG_02936 7.46e-101 - - - - - - - -
AFOFKEHG_02937 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
AFOFKEHG_02938 2.44e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AFOFKEHG_02939 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AFOFKEHG_02940 2.6e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AFOFKEHG_02941 2.54e-243 spsG - - M - - - Spore Coat
AFOFKEHG_02942 4.64e-169 spsF - - M ko:K07257 - ko00000 Spore Coat
AFOFKEHG_02943 6.8e-272 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
AFOFKEHG_02944 4.22e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
AFOFKEHG_02945 1.52e-283 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
AFOFKEHG_02946 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
AFOFKEHG_02947 2.71e-185 spsA - - M - - - Spore Coat
AFOFKEHG_02948 7.61e-114 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
AFOFKEHG_02949 1.59e-78 ywdK - - S - - - small membrane protein
AFOFKEHG_02950 1.78e-301 ywdJ - - F - - - Xanthine uracil
AFOFKEHG_02951 1.31e-64 ywdI - - S - - - Family of unknown function (DUF5327)
AFOFKEHG_02952 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
AFOFKEHG_02953 2.71e-165 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AFOFKEHG_02954 5.69e-193 ywdF - - S - - - Glycosyltransferase like family 2
AFOFKEHG_02956 8.74e-146 ywdD - - - - - - -
AFOFKEHG_02957 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
AFOFKEHG_02958 5.43e-188 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
AFOFKEHG_02959 6.19e-39 ywdA - - - - - - -
AFOFKEHG_02960 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
AFOFKEHG_02961 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
AFOFKEHG_02962 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
AFOFKEHG_02963 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
AFOFKEHG_02965 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
AFOFKEHG_02966 9.87e-238 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFOFKEHG_02967 1.14e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
AFOFKEHG_02968 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
AFOFKEHG_02969 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
AFOFKEHG_02970 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
AFOFKEHG_02971 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
AFOFKEHG_02972 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AFOFKEHG_02973 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
AFOFKEHG_02974 5.11e-49 ydaS - - S - - - membrane
AFOFKEHG_02975 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
AFOFKEHG_02976 5.56e-291 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AFOFKEHG_02977 3.33e-77 gtcA - - S - - - GtrA-like protein
AFOFKEHG_02978 4.16e-159 ywcC - - K - - - transcriptional regulator
AFOFKEHG_02980 2.13e-64 ywcB - - S - - - Protein of unknown function, DUF485
AFOFKEHG_02981 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFOFKEHG_02982 2.44e-142 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
AFOFKEHG_02983 4.18e-303 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
AFOFKEHG_02984 1.46e-247 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
AFOFKEHG_02985 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
AFOFKEHG_02986 7.69e-150 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
AFOFKEHG_02987 3.25e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AFOFKEHG_02988 3.73e-203 ywbI - - K - - - Transcriptional regulator
AFOFKEHG_02989 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
AFOFKEHG_02990 1.21e-143 ywbG - - M - - - effector of murein hydrolase
AFOFKEHG_02991 2.49e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
AFOFKEHG_02992 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
AFOFKEHG_02993 2.31e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
AFOFKEHG_02994 4.01e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
AFOFKEHG_02995 1.09e-121 - - - N - - - domain, Protein
AFOFKEHG_02996 4.33e-162 ywbB - - S - - - Protein of unknown function (DUF2711)
AFOFKEHG_02997 9.36e-317 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFOFKEHG_02998 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
AFOFKEHG_02999 2.79e-310 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
AFOFKEHG_03000 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
AFOFKEHG_03001 2.19e-215 gspA - - M - - - General stress
AFOFKEHG_03002 1.22e-158 ywaF - - S - - - Integral membrane protein
AFOFKEHG_03003 3.57e-114 ywaE - - K - - - Transcriptional regulator
AFOFKEHG_03004 1.5e-295 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AFOFKEHG_03005 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
AFOFKEHG_03006 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
AFOFKEHG_03007 2.83e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
AFOFKEHG_03008 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
AFOFKEHG_03009 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFOFKEHG_03010 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
AFOFKEHG_03011 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFOFKEHG_03012 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AFOFKEHG_03013 1.38e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
AFOFKEHG_03014 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
AFOFKEHG_03015 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
AFOFKEHG_03016 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
AFOFKEHG_03017 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFOFKEHG_03018 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
AFOFKEHG_03019 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
AFOFKEHG_03020 8.94e-28 yxzF - - - - - - -
AFOFKEHG_03021 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
AFOFKEHG_03022 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
AFOFKEHG_03023 2.59e-276 yxlH - - EGP - - - Major Facilitator Superfamily
AFOFKEHG_03024 1.33e-177 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
AFOFKEHG_03025 2.35e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_03026 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
AFOFKEHG_03027 2.92e-42 - - - - - - - -
AFOFKEHG_03028 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
AFOFKEHG_03029 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
AFOFKEHG_03030 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
AFOFKEHG_03031 6.19e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AFOFKEHG_03032 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
AFOFKEHG_03033 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
AFOFKEHG_03034 6.73e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
AFOFKEHG_03035 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
AFOFKEHG_03036 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
AFOFKEHG_03037 0.0 - - - O - - - Peptidase family M48
AFOFKEHG_03039 7.49e-199 yxkH - - G - - - Polysaccharide deacetylase
AFOFKEHG_03040 1.4e-260 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
AFOFKEHG_03041 7.85e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
AFOFKEHG_03042 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
AFOFKEHG_03043 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
AFOFKEHG_03044 1.17e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
AFOFKEHG_03045 4.98e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
AFOFKEHG_03046 1.17e-78 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
AFOFKEHG_03047 3.07e-208 - - - K - - - LysR substrate binding domain
AFOFKEHG_03048 7.69e-100 - - - S - - - Protein of unknown function (DUF1453)
AFOFKEHG_03049 1.37e-258 - - - T - - - Signal transduction histidine kinase
AFOFKEHG_03050 7.4e-146 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
AFOFKEHG_03051 4.49e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
AFOFKEHG_03054 1.43e-111 yxjI - - S - - - LURP-one-related
AFOFKEHG_03055 1.5e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
AFOFKEHG_03056 1.55e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
AFOFKEHG_03057 2.77e-174 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
AFOFKEHG_03058 2.41e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
AFOFKEHG_03059 3.82e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AFOFKEHG_03060 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
AFOFKEHG_03061 9.86e-201 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
AFOFKEHG_03062 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AFOFKEHG_03063 2.37e-123 - - - T - - - Domain of unknown function (DUF4163)
AFOFKEHG_03064 9.3e-63 yxiS - - - - - - -
AFOFKEHG_03065 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
AFOFKEHG_03066 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
AFOFKEHG_03067 3.06e-184 bglS - - M - - - licheninase activity
AFOFKEHG_03068 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
AFOFKEHG_03069 5.09e-141 - - - - - - - -
AFOFKEHG_03070 3.8e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
AFOFKEHG_03071 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
AFOFKEHG_03072 7.41e-276 - - - E - - - GDSL-like Lipase/Acylhydrolase
AFOFKEHG_03075 5.53e-65 yxiJ - - S - - - YxiJ-like protein
AFOFKEHG_03076 3.79e-125 yxiI - - S - - - Protein of unknown function (DUF2716)
AFOFKEHG_03077 6.22e-107 - - - - - - - -
AFOFKEHG_03078 1.2e-57 - - - - - - - -
AFOFKEHG_03079 8.76e-99 yxiG - - - - - - -
AFOFKEHG_03080 1.12e-82 - - - - - - - -
AFOFKEHG_03081 3.69e-111 - - - - - - - -
AFOFKEHG_03082 1.09e-94 yxxG - - - - - - -
AFOFKEHG_03083 0.0 wapA - - M - - - COG3209 Rhs family protein
AFOFKEHG_03084 1.17e-216 yxxF - - EG - - - EamA-like transporter family
AFOFKEHG_03085 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
AFOFKEHG_03086 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
AFOFKEHG_03087 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
AFOFKEHG_03088 1.67e-68 - - - - - - - -
AFOFKEHG_03089 2.33e-273 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
AFOFKEHG_03090 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
AFOFKEHG_03091 1.78e-35 - - - S - - - Domain of unknown function (DUF5082)
AFOFKEHG_03092 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
AFOFKEHG_03093 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
AFOFKEHG_03094 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
AFOFKEHG_03095 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AFOFKEHG_03096 1.64e-301 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
AFOFKEHG_03097 4.85e-231 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
AFOFKEHG_03098 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
AFOFKEHG_03099 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
AFOFKEHG_03100 2.72e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AFOFKEHG_03101 8.3e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AFOFKEHG_03102 4.26e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
AFOFKEHG_03103 2.51e-195 - - - S - - - Domain of Unknown Function (DUF1206)
AFOFKEHG_03104 1.74e-252 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
AFOFKEHG_03105 8.39e-314 yxeQ - - S - - - MmgE/PrpD family
AFOFKEHG_03106 1.17e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
AFOFKEHG_03107 6.82e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_03108 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
AFOFKEHG_03109 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
AFOFKEHG_03110 2.19e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFOFKEHG_03111 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFOFKEHG_03113 1.35e-237 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
AFOFKEHG_03114 8.09e-194 yxeH - - S - - - hydrolases of the HAD superfamily
AFOFKEHG_03117 7.32e-42 yxeE - - - - - - -
AFOFKEHG_03118 7.57e-28 yxeD - - - - - - -
AFOFKEHG_03119 9.65e-91 - - - - - - - -
AFOFKEHG_03120 9.65e-223 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
AFOFKEHG_03121 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
AFOFKEHG_03122 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
AFOFKEHG_03123 3.82e-181 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_03124 1.1e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_03125 3.27e-159 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFOFKEHG_03126 6.95e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
AFOFKEHG_03127 3.79e-187 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
AFOFKEHG_03128 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
AFOFKEHG_03129 2.57e-250 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
AFOFKEHG_03130 1.99e-296 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
AFOFKEHG_03131 4.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
AFOFKEHG_03132 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
AFOFKEHG_03133 5e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
AFOFKEHG_03134 2e-199 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
AFOFKEHG_03135 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
AFOFKEHG_03136 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
AFOFKEHG_03137 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
AFOFKEHG_03139 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
AFOFKEHG_03140 3.41e-312 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
AFOFKEHG_03141 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
AFOFKEHG_03143 2.92e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
AFOFKEHG_03144 4.03e-263 yxbF - - K - - - Bacterial regulatory proteins, tetR family
AFOFKEHG_03145 4.85e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
AFOFKEHG_03146 2.09e-16 yxaI - - S - - - membrane protein domain
AFOFKEHG_03147 9.86e-135 yxaL - - S - - - PQQ-like domain
AFOFKEHG_03148 1.43e-85 - - - S - - - Family of unknown function (DUF5391)
AFOFKEHG_03149 4.7e-98 yxaI - - S - - - membrane protein domain
AFOFKEHG_03150 1.59e-287 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
AFOFKEHG_03151 3.65e-251 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
AFOFKEHG_03152 3.22e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
AFOFKEHG_03153 8.67e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
AFOFKEHG_03154 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
AFOFKEHG_03155 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
AFOFKEHG_03156 2.19e-153 yxaC - - M - - - effector of murein hydrolase
AFOFKEHG_03157 2.34e-241 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
AFOFKEHG_03158 3.87e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
AFOFKEHG_03159 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
AFOFKEHG_03160 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
AFOFKEHG_03161 2.91e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
AFOFKEHG_03162 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AFOFKEHG_03163 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
AFOFKEHG_03164 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
AFOFKEHG_03165 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
AFOFKEHG_03166 6.69e-47 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
AFOFKEHG_03167 6.34e-165 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_03168 1.44e-24 - - - - - - - -
AFOFKEHG_03169 5.49e-152 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
AFOFKEHG_03170 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
AFOFKEHG_03171 6.05e-171 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
AFOFKEHG_03172 7.8e-237 - - - S - - - Radical SAM superfamily
AFOFKEHG_03173 1.99e-17 - - - - - - - -
AFOFKEHG_03174 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
AFOFKEHG_03176 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AFOFKEHG_03178 5.95e-92 - - - - - - - -
AFOFKEHG_03179 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
AFOFKEHG_03181 5.5e-42 yycQ - - S - - - Protein of unknown function (DUF2651)
AFOFKEHG_03182 3.44e-263 yycP - - - - - - -
AFOFKEHG_03183 1.96e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AFOFKEHG_03184 7.45e-111 yycN - - K - - - Acetyltransferase
AFOFKEHG_03185 7.14e-238 - - - S - - - aspartate phosphatase
AFOFKEHG_03187 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
AFOFKEHG_03188 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
AFOFKEHG_03189 5.84e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
AFOFKEHG_03190 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
AFOFKEHG_03191 1.95e-216 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
AFOFKEHG_03192 2.36e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
AFOFKEHG_03193 3.28e-98 - - - S - - - Peptidase propeptide and YPEB domain
AFOFKEHG_03194 2.2e-42 - - - S - - - Peptidase propeptide and YPEB domain
AFOFKEHG_03195 1.05e-275 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFOFKEHG_03196 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
AFOFKEHG_03197 4.88e-200 yycI - - S - - - protein conserved in bacteria
AFOFKEHG_03198 0.0 yycH - - S - - - protein conserved in bacteria
AFOFKEHG_03199 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_03200 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFOFKEHG_03205 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AFOFKEHG_03206 3.29e-99 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFOFKEHG_03207 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
AFOFKEHG_03208 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
AFOFKEHG_03210 1.89e-22 yycC - - K - - - YycC-like protein
AFOFKEHG_03211 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
AFOFKEHG_03212 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AFOFKEHG_03213 5.52e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
AFOFKEHG_03214 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
AFOFKEHG_03215 1.5e-204 yybS - - S - - - membrane
AFOFKEHG_03217 6.83e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
AFOFKEHG_03218 6.43e-88 yybR - - K - - - Transcriptional regulator
AFOFKEHG_03219 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
AFOFKEHG_03220 7.84e-91 - - - - - - - -
AFOFKEHG_03222 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_03223 4.38e-142 - - - K - - - TipAS antibiotic-recognition domain
AFOFKEHG_03224 9.72e-182 - - - - - - - -
AFOFKEHG_03225 5.02e-87 - - - S - - - SnoaL-like domain
AFOFKEHG_03226 2.31e-161 yybG - - S - - - Pentapeptide repeat-containing protein
AFOFKEHG_03227 4.12e-275 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_03228 3.21e-211 yybE - - K - - - Transcriptional regulator
AFOFKEHG_03229 7.91e-104 yjcF - - S - - - Acetyltransferase (GNAT) domain
AFOFKEHG_03230 2.99e-98 yybC - - - - - - -
AFOFKEHG_03231 5.29e-165 - - - S - - - Metallo-beta-lactamase superfamily
AFOFKEHG_03232 4.54e-100 yybA - - K - - - transcriptional
AFOFKEHG_03233 2.85e-93 yjcF - - S - - - Acetyltransferase (GNAT) domain
AFOFKEHG_03234 8.63e-125 yyaS - - S ko:K07149 - ko00000 Membrane
AFOFKEHG_03235 3.86e-119 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
AFOFKEHG_03236 1.82e-86 - - - S - - - YjbR
AFOFKEHG_03237 8.28e-135 yyaP - - H - - - RibD C-terminal domain
AFOFKEHG_03238 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_03239 1.46e-58 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
AFOFKEHG_03240 5.45e-88 - - - K - - - MerR HTH family regulatory protein
AFOFKEHG_03241 1.9e-205 - - - EG - - - EamA-like transporter family
AFOFKEHG_03242 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
AFOFKEHG_03243 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
AFOFKEHG_03244 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
AFOFKEHG_03245 3.81e-129 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
AFOFKEHG_03246 2.32e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFOFKEHG_03247 6.85e-227 ccpB - - K - - - Transcriptional regulator
AFOFKEHG_03248 7.76e-183 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
AFOFKEHG_03249 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AFOFKEHG_03250 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AFOFKEHG_03251 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
AFOFKEHG_03252 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AFOFKEHG_03253 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AFOFKEHG_03254 7.41e-45 yyzM - - S - - - protein conserved in bacteria
AFOFKEHG_03255 5.34e-227 yyaD - - S - - - Membrane
AFOFKEHG_03256 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
AFOFKEHG_03257 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
AFOFKEHG_03258 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
AFOFKEHG_03259 9.26e-98 - - - S - - - Bacterial PH domain
AFOFKEHG_03260 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
AFOFKEHG_03261 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
AFOFKEHG_03262 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AFOFKEHG_03263 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AFOFKEHG_03264 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
AFOFKEHG_03265 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFOFKEHG_03266 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AFOFKEHG_03267 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AFOFKEHG_03268 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AFOFKEHG_03269 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
AFOFKEHG_03270 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AFOFKEHG_03271 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
AFOFKEHG_03272 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFOFKEHG_03273 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFOFKEHG_03276 3.06e-237 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AFOFKEHG_03277 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
AFOFKEHG_03278 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
AFOFKEHG_03279 2.84e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
AFOFKEHG_03280 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AFOFKEHG_03281 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
AFOFKEHG_03282 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
AFOFKEHG_03283 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AFOFKEHG_03284 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
AFOFKEHG_03285 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AFOFKEHG_03286 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
AFOFKEHG_03287 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
AFOFKEHG_03288 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AFOFKEHG_03289 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AFOFKEHG_03291 2.82e-87 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
AFOFKEHG_03292 0.0 dcm 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
AFOFKEHG_03293 1.43e-297 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
AFOFKEHG_03295 3.67e-254 - - - V - - - AAA domain (dynein-related subfamily)
AFOFKEHG_03296 0.0 - - - J - - - LlaJI restriction endonuclease
AFOFKEHG_03297 3.73e-11 ydjC - - S - - - Abhydrolase domain containing 18
AFOFKEHG_03298 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
AFOFKEHG_03299 1.06e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
AFOFKEHG_03300 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
AFOFKEHG_03301 5.39e-224 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
AFOFKEHG_03302 6.25e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
AFOFKEHG_03303 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AFOFKEHG_03304 3e-172 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
AFOFKEHG_03305 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
AFOFKEHG_03306 4.59e-247 - - - S - - - Ion transport 2 domain protein
AFOFKEHG_03307 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
AFOFKEHG_03308 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
AFOFKEHG_03309 1.79e-84 ydjM - - M - - - Lytic transglycolase
AFOFKEHG_03310 3.28e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
AFOFKEHG_03312 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
AFOFKEHG_03313 1.2e-200 - - - I - - - Alpha/beta hydrolase family
AFOFKEHG_03314 7.65e-226 yeaA - - S - - - Protein of unknown function (DUF4003)
AFOFKEHG_03315 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
AFOFKEHG_03316 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
AFOFKEHG_03317 6.13e-199 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFOFKEHG_03318 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
AFOFKEHG_03319 3.2e-285 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
AFOFKEHG_03320 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
AFOFKEHG_03321 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
AFOFKEHG_03322 1.7e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
AFOFKEHG_03323 2.38e-164 yebC - - M - - - Membrane
AFOFKEHG_03325 2.66e-120 yebE - - S - - - UPF0316 protein
AFOFKEHG_03326 3.13e-38 yebG - - S - - - NETI protein
AFOFKEHG_03327 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AFOFKEHG_03328 3.55e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AFOFKEHG_03329 1.98e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AFOFKEHG_03330 2.78e-166 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
AFOFKEHG_03331 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFOFKEHG_03332 6.66e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFOFKEHG_03333 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFOFKEHG_03334 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AFOFKEHG_03335 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
AFOFKEHG_03336 5.14e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AFOFKEHG_03337 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
AFOFKEHG_03338 1.9e-296 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
AFOFKEHG_03339 7.2e-92 - - - K - - - helix_turn_helix ASNC type
AFOFKEHG_03340 9.05e-296 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
AFOFKEHG_03341 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
AFOFKEHG_03342 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
AFOFKEHG_03343 7.03e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
AFOFKEHG_03344 7.62e-68 yerC - - S - - - protein conserved in bacteria
AFOFKEHG_03345 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
AFOFKEHG_03347 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AFOFKEHG_03348 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
AFOFKEHG_03349 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AFOFKEHG_03350 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
AFOFKEHG_03351 2.1e-251 yerI - - S - - - homoserine kinase type II (protein kinase fold)
AFOFKEHG_03352 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
AFOFKEHG_03353 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFOFKEHG_03354 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFOFKEHG_03355 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AFOFKEHG_03356 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFOFKEHG_03357 1.47e-190 yerO - - K - - - Transcriptional regulator
AFOFKEHG_03358 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AFOFKEHG_03359 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
AFOFKEHG_03360 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFOFKEHG_03361 3.63e-127 - - - L - - - Recombinase
AFOFKEHG_03362 5.61e-71 - - - L - - - Resolvase, N terminal domain
AFOFKEHG_03363 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
AFOFKEHG_03364 0.0 - - - L - - - DEAD-like helicases superfamily
AFOFKEHG_03365 1.13e-270 yeeC - - P - - - T5orf172
AFOFKEHG_03366 7.48e-05 - - - - - - - -
AFOFKEHG_03367 4.15e-42 - - - S - - - Colicin immunity protein / pyocin immunity protein
AFOFKEHG_03368 2.1e-109 - - - S - - - Protein of unknown function, DUF600
AFOFKEHG_03369 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
AFOFKEHG_03371 8.81e-155 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
AFOFKEHG_03372 3.52e-71 - - - - - - - -
AFOFKEHG_03373 4.24e-14 - - - S - - - Pfam:DUF1311
AFOFKEHG_03374 1.49e-272 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
AFOFKEHG_03376 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
AFOFKEHG_03378 1.86e-134 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
AFOFKEHG_03379 2.02e-104 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
AFOFKEHG_03380 8.16e-187 yesF - - GM - - - NAD(P)H-binding
AFOFKEHG_03381 1.55e-59 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
AFOFKEHG_03382 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
AFOFKEHG_03383 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
AFOFKEHG_03384 6.88e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
AFOFKEHG_03386 1.38e-132 yesL - - S - - - Protein of unknown function, DUF624
AFOFKEHG_03387 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_03388 8.04e-257 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
AFOFKEHG_03389 1.38e-312 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
AFOFKEHG_03390 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AFOFKEHG_03391 1.31e-212 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AFOFKEHG_03392 1.96e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
AFOFKEHG_03393 0.0 yesS - - K - - - Transcriptional regulator
AFOFKEHG_03394 3.56e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
AFOFKEHG_03395 1.41e-169 yesU - - S - - - Domain of unknown function (DUF1961)
AFOFKEHG_03396 3.44e-146 - - - S - - - Protein of unknown function, DUF624
AFOFKEHG_03397 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
AFOFKEHG_03398 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
AFOFKEHG_03400 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
AFOFKEHG_03401 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
AFOFKEHG_03402 0.0 yetA - - - - - - -
AFOFKEHG_03403 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
AFOFKEHG_03404 9.71e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
AFOFKEHG_03405 3.19e-208 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
AFOFKEHG_03406 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
AFOFKEHG_03407 3.13e-158 yetF - - S - - - membrane
AFOFKEHG_03408 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
AFOFKEHG_03409 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFOFKEHG_03410 1.75e-44 - - - - - - - -
AFOFKEHG_03411 8.16e-139 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
AFOFKEHG_03412 1.55e-27 yezD - - S - - - Uncharacterized small protein (DUF2292)
AFOFKEHG_03413 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
AFOFKEHG_03414 7.35e-203 - - - EG - - - EamA-like transporter family
AFOFKEHG_03415 6.74e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
AFOFKEHG_03416 4.9e-263 yetM - - CH - - - FAD binding domain
AFOFKEHG_03417 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
AFOFKEHG_03418 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
AFOFKEHG_03419 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
AFOFKEHG_03420 1.02e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
AFOFKEHG_03421 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
AFOFKEHG_03422 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
AFOFKEHG_03423 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
AFOFKEHG_03424 3.88e-242 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
AFOFKEHG_03425 1.46e-266 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_03426 1.29e-168 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
AFOFKEHG_03427 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
AFOFKEHG_03428 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
AFOFKEHG_03429 5.14e-161 yfmS - - NT - - - chemotaxis protein
AFOFKEHG_03430 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
AFOFKEHG_03431 1.31e-98 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
AFOFKEHG_03432 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
AFOFKEHG_03433 7.24e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
AFOFKEHG_03434 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
AFOFKEHG_03435 1.86e-266 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
AFOFKEHG_03436 1.86e-107 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
AFOFKEHG_03437 4.21e-242 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
AFOFKEHG_03438 3.46e-268 - - - G - - - Major Facilitator Superfamily
AFOFKEHG_03439 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
AFOFKEHG_03440 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
AFOFKEHG_03441 2.73e-219 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFOFKEHG_03442 4.72e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFOFKEHG_03443 3.36e-220 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
AFOFKEHG_03444 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
AFOFKEHG_03445 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
AFOFKEHG_03446 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
AFOFKEHG_03447 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
AFOFKEHG_03448 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
AFOFKEHG_03449 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
AFOFKEHG_03450 1.97e-230 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
AFOFKEHG_03451 1.53e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
AFOFKEHG_03452 7.21e-194 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
AFOFKEHG_03453 1.43e-277 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AFOFKEHG_03454 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
AFOFKEHG_03455 2.51e-159 yflK - - S - - - protein conserved in bacteria
AFOFKEHG_03456 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
AFOFKEHG_03457 6.9e-27 yflI - - - - - - -
AFOFKEHG_03458 3.63e-66 yflH - - S - - - Protein of unknown function (DUF3243)
AFOFKEHG_03459 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
AFOFKEHG_03460 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
AFOFKEHG_03461 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
AFOFKEHG_03462 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
AFOFKEHG_03463 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
AFOFKEHG_03464 2.19e-249 yfkT - - E ko:K06309 - ko00000 Spore germination protein
AFOFKEHG_03466 2.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
AFOFKEHG_03467 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
AFOFKEHG_03468 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
AFOFKEHG_03469 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
AFOFKEHG_03470 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
AFOFKEHG_03471 6.16e-160 frp - - C - - - nitroreductase
AFOFKEHG_03472 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
AFOFKEHG_03473 7.78e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
AFOFKEHG_03474 2.53e-265 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_03475 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
AFOFKEHG_03476 9.78e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AFOFKEHG_03477 1.03e-66 yfkI - - S - - - gas vesicle protein
AFOFKEHG_03478 1.6e-182 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
AFOFKEHG_03479 1.64e-12 - - - - - - - -
AFOFKEHG_03480 3.84e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_03481 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
AFOFKEHG_03482 3.69e-189 yfkD - - S - - - YfkD-like protein
AFOFKEHG_03483 1.49e-189 yfkC - - M - - - Mechanosensitive ion channel
AFOFKEHG_03484 1.76e-283 yfkA - - S - - - YfkB-like domain
AFOFKEHG_03485 3.26e-36 yfjT - - - - - - -
AFOFKEHG_03486 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
AFOFKEHG_03487 1.32e-191 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
AFOFKEHG_03488 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
AFOFKEHG_03489 1.94e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AFOFKEHG_03490 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFOFKEHG_03491 1.45e-57 - - - S - - - YfzA-like protein
AFOFKEHG_03492 1.21e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AFOFKEHG_03493 9.55e-111 yfjM - - S - - - Psort location Cytoplasmic, score
AFOFKEHG_03494 9.2e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
AFOFKEHG_03495 2.64e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AFOFKEHG_03496 2.7e-261 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AFOFKEHG_03497 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
AFOFKEHG_03498 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
AFOFKEHG_03499 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
AFOFKEHG_03500 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
AFOFKEHG_03501 1.9e-109 - - - S - - - Family of unknown function (DUF5381)
AFOFKEHG_03502 3.83e-161 yfjC - - - - - - -
AFOFKEHG_03503 6.91e-241 yfjB - - - - - - -
AFOFKEHG_03504 1.6e-60 yfjA - - S - - - Belongs to the WXG100 family
AFOFKEHG_03505 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
AFOFKEHG_03506 7.45e-182 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
AFOFKEHG_03507 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
AFOFKEHG_03508 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
AFOFKEHG_03509 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
AFOFKEHG_03510 3.34e-83 yfiD3 - - S - - - DoxX
AFOFKEHG_03511 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
AFOFKEHG_03513 1.98e-271 baeS - - T - - - Histidine kinase
AFOFKEHG_03514 6.07e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
AFOFKEHG_03515 7.89e-217 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_03516 1.46e-264 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
AFOFKEHG_03517 1.56e-258 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
AFOFKEHG_03518 1.89e-128 padR - - K - - - transcriptional
AFOFKEHG_03519 3.2e-127 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
AFOFKEHG_03520 8.95e-251 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AFOFKEHG_03521 4e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
AFOFKEHG_03522 0.0 yfiU - - EGP - - - the major facilitator superfamily
AFOFKEHG_03523 2.11e-103 yfiV - - K - - - transcriptional
AFOFKEHG_03524 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AFOFKEHG_03525 1.56e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
AFOFKEHG_03526 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFOFKEHG_03527 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFOFKEHG_03528 1.04e-212 yfhB - - S - - - PhzF family
AFOFKEHG_03529 1.94e-136 yfhC - - C - - - nitroreductase
AFOFKEHG_03530 8.86e-35 yfhD - - S - - - YfhD-like protein
AFOFKEHG_03532 3.79e-220 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
AFOFKEHG_03533 3.8e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
AFOFKEHG_03534 1.32e-68 yfhH - - S - - - Protein of unknown function (DUF1811)
AFOFKEHG_03535 9.96e-268 yfhI - - EGP - - - -transporter
AFOFKEHG_03536 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
AFOFKEHG_03537 8.95e-60 yfhJ - - S - - - WVELL protein
AFOFKEHG_03538 2.94e-118 yfhK - - T - - - Bacterial SH3 domain homologues
AFOFKEHG_03539 1.27e-65 yfhL - - S - - - SdpI/YhfL protein family
AFOFKEHG_03540 3.23e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
AFOFKEHG_03541 8.09e-235 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
AFOFKEHG_03542 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
AFOFKEHG_03543 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
AFOFKEHG_03544 1.2e-267 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
AFOFKEHG_03545 1.73e-48 yfhS - - - - - - -
AFOFKEHG_03546 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFOFKEHG_03547 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
AFOFKEHG_03548 2.01e-49 ygaB - - S - - - YgaB-like protein
AFOFKEHG_03549 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
AFOFKEHG_03550 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
AFOFKEHG_03551 1.87e-238 ygaE - - S - - - Membrane
AFOFKEHG_03552 1.19e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
AFOFKEHG_03553 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
AFOFKEHG_03554 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
AFOFKEHG_03555 4.67e-75 ygzB - - S - - - UPF0295 protein
AFOFKEHG_03556 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
AFOFKEHG_03559 6.94e-202 ydhU - - P ko:K07217 - ko00000 Catalase
AFOFKEHG_03560 2.02e-272 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
AFOFKEHG_03561 5.3e-242 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
AFOFKEHG_03562 9.28e-219 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
AFOFKEHG_03563 1.9e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
AFOFKEHG_03564 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
AFOFKEHG_03565 9.72e-301 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFOFKEHG_03566 5.86e-68 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
AFOFKEHG_03567 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
AFOFKEHG_03568 2.56e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
AFOFKEHG_03569 3.29e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
AFOFKEHG_03570 1.05e-228 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
AFOFKEHG_03571 3.25e-109 - - - K - - - Acetyltransferase (GNAT) domain
AFOFKEHG_03573 3.33e-89 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
AFOFKEHG_03574 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
AFOFKEHG_03575 3.52e-162 - - - - - - - -
AFOFKEHG_03576 1.94e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
AFOFKEHG_03577 4.24e-308 ydhD - - M - - - Glycosyl hydrolase
AFOFKEHG_03578 5.24e-158 ydhC - - K - - - FCD
AFOFKEHG_03579 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
AFOFKEHG_03580 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
AFOFKEHG_03581 3.29e-90 - - - K - - - Winged helix DNA-binding domain
AFOFKEHG_03582 6.42e-147 ydgI - - C - - - nitroreductase
AFOFKEHG_03583 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
AFOFKEHG_03584 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
AFOFKEHG_03585 5.09e-119 - - - S - - - DinB family
AFOFKEHG_03586 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
AFOFKEHG_03587 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
AFOFKEHG_03588 2.49e-114 yycN - - K - - - Acetyltransferase
AFOFKEHG_03589 3.47e-71 - - - S - - - DoxX-like family
AFOFKEHG_03590 7.86e-132 ydgC - - K - - - Bacterial regulatory proteins, tetR family
AFOFKEHG_03591 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
AFOFKEHG_03592 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
AFOFKEHG_03593 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
AFOFKEHG_03594 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
AFOFKEHG_03595 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
AFOFKEHG_03597 5.33e-39 - - - - - - - -
AFOFKEHG_03598 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
AFOFKEHG_03600 9.63e-77 ydfQ - - CO - - - Thioredoxin
AFOFKEHG_03601 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
AFOFKEHG_03602 9.49e-239 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
AFOFKEHG_03603 2.83e-144 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
AFOFKEHG_03604 5.22e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFOFKEHG_03605 1.18e-186 - - - K - - - Bacterial transcription activator, effector binding domain
AFOFKEHG_03606 3.77e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
AFOFKEHG_03607 1.05e-220 - - - S - - - Alpha/beta hydrolase family
AFOFKEHG_03608 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
AFOFKEHG_03609 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFOFKEHG_03610 3.37e-252 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_03612 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AFOFKEHG_03613 7.44e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
AFOFKEHG_03614 4.71e-148 ydfE - - S - - - Flavin reductase like domain
AFOFKEHG_03615 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFOFKEHG_03616 5.17e-199 - - - EG - - - EamA-like transporter family
AFOFKEHG_03617 1.01e-184 - - - J - - - GNAT acetyltransferase
AFOFKEHG_03618 9.07e-297 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AFOFKEHG_03619 2.56e-76 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
AFOFKEHG_03620 3.74e-136 ydeS - - K - - - Transcriptional regulator
AFOFKEHG_03621 1.51e-261 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
AFOFKEHG_03622 2.44e-142 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
AFOFKEHG_03623 5.03e-91 ydeP - - K - - - Transcriptional regulator
AFOFKEHG_03624 1.68e-196 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
AFOFKEHG_03625 1.33e-77 - - - K - - - HxlR-like helix-turn-helix
AFOFKEHG_03626 8.6e-138 - - - S ko:K07002 - ko00000 Serine hydrolase
AFOFKEHG_03627 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
AFOFKEHG_03628 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFOFKEHG_03629 4.66e-197 ydeK - - EG - - - -transporter
AFOFKEHG_03630 6.11e-150 - - - - - - - -
AFOFKEHG_03631 1.26e-138 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
AFOFKEHG_03632 4.76e-72 ydeH - - - - - - -
AFOFKEHG_03633 1.19e-280 ydeG - - EGP - - - Major facilitator superfamily
AFOFKEHG_03634 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFOFKEHG_03635 2.87e-213 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
AFOFKEHG_03636 4.99e-224 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
AFOFKEHG_03637 3.23e-215 - - - K - - - AraC-like ligand binding domain
AFOFKEHG_03638 2.47e-47 ydzE - - EG - - - spore germination
AFOFKEHG_03639 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
AFOFKEHG_03640 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
AFOFKEHG_03641 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
AFOFKEHG_03646 3.35e-288 ydeG3 - - EGP - - - Major Facilitator Superfamily
AFOFKEHG_03647 1.34e-184 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
AFOFKEHG_03648 1.62e-128 yddQ - - Q - - - Isochorismatase family
AFOFKEHG_03649 1.26e-101 lrpB - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
AFOFKEHG_03650 8.15e-94 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
AFOFKEHG_03651 2.43e-241 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFOFKEHG_03659 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
AFOFKEHG_03660 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
AFOFKEHG_03661 7.57e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
AFOFKEHG_03662 3.12e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFOFKEHG_03663 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
AFOFKEHG_03664 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
AFOFKEHG_03665 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
AFOFKEHG_03666 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
AFOFKEHG_03667 7.34e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
AFOFKEHG_03668 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
AFOFKEHG_03669 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
AFOFKEHG_03670 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
AFOFKEHG_03671 5.29e-284 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AFOFKEHG_03672 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
AFOFKEHG_03673 1.95e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AFOFKEHG_03674 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
AFOFKEHG_03675 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
AFOFKEHG_03676 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
AFOFKEHG_03677 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AFOFKEHG_03678 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AFOFKEHG_03679 3.07e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
AFOFKEHG_03680 4.19e-75 ydbP - - CO - - - Thioredoxin
AFOFKEHG_03681 1.91e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFOFKEHG_03683 1.49e-26 - - - S - - - Fur-regulated basic protein B
AFOFKEHG_03684 1.83e-280 ydbM - - I - - - acyl-CoA dehydrogenase
AFOFKEHG_03685 9.32e-70 ydbL - - - - - - -
AFOFKEHG_03686 7.34e-160 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
AFOFKEHG_03687 3.23e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_03688 1.32e-230 ydbI - - S - - - AI-2E family transporter
AFOFKEHG_03689 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFOFKEHG_03690 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
AFOFKEHG_03691 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
AFOFKEHG_03692 3.66e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
AFOFKEHG_03693 1.35e-198 ydbD - - P ko:K07217 - ko00000 Catalase
AFOFKEHG_03694 5.41e-84 ydbC - - S - - - Domain of unknown function (DUF4937
AFOFKEHG_03695 1.26e-77 ydbB - - G - - - Cupin domain
AFOFKEHG_03696 3.3e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
AFOFKEHG_03697 1.75e-189 ydbA - - P - - - EcsC protein family
AFOFKEHG_03698 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
AFOFKEHG_03699 1.67e-42 ydaS - - S - - - membrane
AFOFKEHG_03700 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
AFOFKEHG_03701 6.14e-53 - - - - - - - -
AFOFKEHG_03702 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
AFOFKEHG_03703 1.79e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
AFOFKEHG_03704 0.0 ydaO - - E - - - amino acid
AFOFKEHG_03705 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
AFOFKEHG_03706 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
AFOFKEHG_03707 2.12e-309 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
AFOFKEHG_03708 3.81e-53 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
AFOFKEHG_03709 1.33e-194 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
AFOFKEHG_03710 3.45e-264 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
AFOFKEHG_03711 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AFOFKEHG_03712 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
AFOFKEHG_03713 3.65e-60 ydzA - - EGP - - - Domain of unknown function (DUF3817)
AFOFKEHG_03714 1.87e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
AFOFKEHG_03715 5.24e-101 ydaG - - S - - - general stress protein
AFOFKEHG_03716 2.58e-131 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
AFOFKEHG_03717 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
AFOFKEHG_03718 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFOFKEHG_03719 1e-127 ydaC - - Q - - - Methyltransferase domain
AFOFKEHG_03720 0.0 ydaB - - IQ - - - acyl-CoA ligase
AFOFKEHG_03721 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
AFOFKEHG_03722 3.26e-224 ycsN - - S - - - Oxidoreductase
AFOFKEHG_03723 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
AFOFKEHG_03724 7.67e-66 yczJ - - S - - - biosynthesis
AFOFKEHG_03726 4.18e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
AFOFKEHG_03727 3.8e-171 kipR - - K - - - Transcriptional regulator
AFOFKEHG_03728 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
AFOFKEHG_03729 5.04e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
AFOFKEHG_03730 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
AFOFKEHG_03731 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
AFOFKEHG_03732 9.39e-182 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
AFOFKEHG_03733 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
AFOFKEHG_03735 2.29e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
AFOFKEHG_03736 4.21e-144 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
AFOFKEHG_03737 1.32e-126 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
AFOFKEHG_03738 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
AFOFKEHG_03739 5.13e-267 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
AFOFKEHG_03740 2.38e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
AFOFKEHG_03741 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
AFOFKEHG_03742 9.44e-75 - - - - - - - -
AFOFKEHG_03743 2.88e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
AFOFKEHG_03744 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
AFOFKEHG_03745 3.99e-134 ycnI - - S - - - protein conserved in bacteria
AFOFKEHG_03746 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFOFKEHG_03747 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
AFOFKEHG_03748 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
AFOFKEHG_03749 2.4e-313 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AFOFKEHG_03750 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFOFKEHG_03751 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
AFOFKEHG_03752 1.68e-60 ycnE - - S - - - Monooxygenase
AFOFKEHG_03753 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
AFOFKEHG_03754 1.38e-196 ycnC - - K - - - Transcriptional regulator
AFOFKEHG_03755 0.0 ycnB - - EGP - - - the major facilitator superfamily
AFOFKEHG_03756 2.33e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
AFOFKEHG_03757 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_03758 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFOFKEHG_03759 5.42e-206 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFOFKEHG_03760 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
AFOFKEHG_03761 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
AFOFKEHG_03763 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
AFOFKEHG_03764 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
AFOFKEHG_03765 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFOFKEHG_03766 5.59e-280 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
AFOFKEHG_03767 2.05e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
AFOFKEHG_03768 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
AFOFKEHG_03769 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
AFOFKEHG_03770 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
AFOFKEHG_03772 0.0 yclG - - M - - - Pectate lyase superfamily protein
AFOFKEHG_03773 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
AFOFKEHG_03774 6.42e-201 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
AFOFKEHG_03775 9.83e-106 yclD - - - - - - -
AFOFKEHG_03776 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
AFOFKEHG_03777 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
AFOFKEHG_03778 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
AFOFKEHG_03779 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
AFOFKEHG_03780 1.75e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
AFOFKEHG_03781 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
AFOFKEHG_03782 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
AFOFKEHG_03783 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
AFOFKEHG_03784 4.76e-145 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
AFOFKEHG_03785 0.0 ycxD - - K - - - GntR family transcriptional regulator
AFOFKEHG_03786 3.27e-205 ycxC - - EG - - - EamA-like transporter family
AFOFKEHG_03787 1.17e-119 - - - S - - - YcxB-like protein
AFOFKEHG_03788 4.41e-288 - - - EGP - - - Major Facilitator Superfamily
AFOFKEHG_03789 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
AFOFKEHG_03790 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
AFOFKEHG_03791 4.89e-274 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFOFKEHG_03792 6.05e-86 hxlR - - K - - - transcriptional
AFOFKEHG_03793 2.39e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
AFOFKEHG_03794 1.38e-127 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
AFOFKEHG_03795 6.52e-269 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
AFOFKEHG_03796 4.78e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
AFOFKEHG_03797 7.06e-93 nin - - S - - - Competence protein J (ComJ)
AFOFKEHG_03798 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
AFOFKEHG_03799 2.39e-67 yckD - - S - - - Protein of unknown function (DUF2680)
AFOFKEHG_03801 3.76e-187 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
AFOFKEHG_03802 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
AFOFKEHG_03803 6.78e-291 yciC - - S - - - GTPases (G3E family)
AFOFKEHG_03804 2.97e-131 - - - M - - - ErfK YbiS YcfS YnhG
AFOFKEHG_03805 7.92e-218 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
AFOFKEHG_03806 6.43e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
AFOFKEHG_03807 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
AFOFKEHG_03808 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AFOFKEHG_03809 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AFOFKEHG_03810 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
AFOFKEHG_03811 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
AFOFKEHG_03812 8.9e-247 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
AFOFKEHG_03813 4.74e-209 ycgS - - I - - - alpha/beta hydrolase fold
AFOFKEHG_03814 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
AFOFKEHG_03815 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
AFOFKEHG_03816 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
AFOFKEHG_03817 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFOFKEHG_03818 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
AFOFKEHG_03819 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
AFOFKEHG_03820 7.76e-187 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
AFOFKEHG_03821 2.32e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
AFOFKEHG_03822 2.05e-230 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
AFOFKEHG_03823 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
AFOFKEHG_03824 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AFOFKEHG_03826 3.09e-139 tmrB - - S - - - AAA domain
AFOFKEHG_03827 5.24e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AFOFKEHG_03828 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
AFOFKEHG_03829 9.32e-317 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
AFOFKEHG_03830 3.07e-194 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
AFOFKEHG_03831 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
AFOFKEHG_03832 1.51e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
AFOFKEHG_03833 0.0 mdr - - EGP - - - the major facilitator superfamily
AFOFKEHG_03834 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
AFOFKEHG_03835 1.69e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
AFOFKEHG_03836 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
AFOFKEHG_03837 2.72e-105 ycgB - - - - - - -
AFOFKEHG_03838 0.0 ycgA - - S - - - Membrane
AFOFKEHG_03839 1.97e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
AFOFKEHG_03840 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
AFOFKEHG_03841 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
AFOFKEHG_03842 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
AFOFKEHG_03843 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
AFOFKEHG_03844 1.17e-267 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
AFOFKEHG_03845 2.32e-279 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
AFOFKEHG_03846 2.96e-245 yceH - - P - - - Belongs to the TelA family
AFOFKEHG_03847 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
AFOFKEHG_03848 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
AFOFKEHG_03849 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
AFOFKEHG_03850 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
AFOFKEHG_03851 1.08e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
AFOFKEHG_03852 9.18e-242 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFOFKEHG_03853 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
AFOFKEHG_03854 1.99e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
AFOFKEHG_03855 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
AFOFKEHG_03856 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
AFOFKEHG_03857 6.85e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
AFOFKEHG_03858 1.16e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
AFOFKEHG_03859 2.18e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
AFOFKEHG_03860 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
AFOFKEHG_03861 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
AFOFKEHG_03862 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
AFOFKEHG_03863 9.67e-222 yccK - - C - - - Aldo keto reductase
AFOFKEHG_03864 5.64e-257 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
AFOFKEHG_03865 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
AFOFKEHG_03866 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
AFOFKEHG_03867 1.35e-214 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
AFOFKEHG_03868 2.49e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
AFOFKEHG_03869 1.14e-73 - - - S - - - RDD family
AFOFKEHG_03870 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
AFOFKEHG_03871 2.4e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
AFOFKEHG_03872 1.88e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
AFOFKEHG_03873 2.51e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
AFOFKEHG_03874 2.16e-262 ycbU - - E - - - Selenocysteine lyase
AFOFKEHG_03875 9.85e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AFOFKEHG_03876 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AFOFKEHG_03877 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
AFOFKEHG_03878 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
AFOFKEHG_03879 4.66e-175 ycbR - - T - - - vWA found in TerF C terminus
AFOFKEHG_03880 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
AFOFKEHG_03881 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
AFOFKEHG_03882 2.75e-146 - - - S - - - ABC-2 family transporter protein
AFOFKEHG_03883 9.2e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
AFOFKEHG_03884 1.59e-216 ycbM - - T - - - Histidine kinase
AFOFKEHG_03885 2.22e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFOFKEHG_03886 1.87e-220 eamA1 - - EG - - - spore germination
AFOFKEHG_03887 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
AFOFKEHG_03888 1.74e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
AFOFKEHG_03889 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
AFOFKEHG_03890 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
AFOFKEHG_03891 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
AFOFKEHG_03892 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_03893 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
AFOFKEHG_03894 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
AFOFKEHG_03895 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
AFOFKEHG_03896 1.19e-292 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
AFOFKEHG_03897 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
AFOFKEHG_03898 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
AFOFKEHG_03899 1.29e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
AFOFKEHG_03900 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
AFOFKEHG_03901 9.84e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
AFOFKEHG_03903 3.4e-164 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
AFOFKEHG_03904 7.41e-175 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AFOFKEHG_03905 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
AFOFKEHG_03906 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFOFKEHG_03907 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
AFOFKEHG_03908 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
AFOFKEHG_03909 9.17e-59 ybfN - - - - - - -
AFOFKEHG_03910 2.06e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
AFOFKEHG_03911 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
AFOFKEHG_03912 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFOFKEHG_03913 5.8e-216 - - - S - - - Alpha/beta hydrolase family
AFOFKEHG_03915 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
AFOFKEHG_03916 1.87e-270 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AFOFKEHG_03917 2.12e-187 ybfI - - K - - - AraC-like ligand binding domain
AFOFKEHG_03918 5.27e-208 ybfH - - EG - - - EamA-like transporter family
AFOFKEHG_03919 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
AFOFKEHG_03921 2.36e-287 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_03922 8.93e-220 ybfA - - K - - - FR47-like protein
AFOFKEHG_03923 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
AFOFKEHG_03924 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
AFOFKEHG_03925 7.3e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
AFOFKEHG_03926 0.0 ybeC - - E - - - amino acid
AFOFKEHG_03927 1.11e-54 ybyB - - - - - - -
AFOFKEHG_03928 6.76e-308 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
AFOFKEHG_03929 3.71e-193 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
AFOFKEHG_03930 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
AFOFKEHG_03931 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
AFOFKEHG_03932 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
AFOFKEHG_03933 1.55e-274 ybdO - - S - - - Domain of unknown function (DUF4885)
AFOFKEHG_03934 4.46e-194 ybdN - - - - - - -
AFOFKEHG_03935 2.49e-181 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
AFOFKEHG_03937 4.12e-221 - - - T - - - His Kinase A (phospho-acceptor) domain
AFOFKEHG_03938 2.93e-159 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
AFOFKEHG_03939 8.07e-233 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
AFOFKEHG_03940 5.88e-103 - - - CO - - - Thioredoxin-like domain
AFOFKEHG_03941 3.88e-118 - - - C - - - HEAT repeats
AFOFKEHG_03942 3.99e-313 skfF - - S - - - ABC transporter
AFOFKEHG_03943 8.07e-174 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
AFOFKEHG_03944 0.0 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
AFOFKEHG_03945 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
AFOFKEHG_03947 1.62e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
AFOFKEHG_03948 9.45e-67 - - - K - - - Helix-turn-helix domain
AFOFKEHG_03949 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
AFOFKEHG_03950 5.59e-64 - - - - - - - -
AFOFKEHG_03951 2.51e-125 ybcF - - P - - - carbonic anhydrase
AFOFKEHG_03952 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
AFOFKEHG_03953 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
AFOFKEHG_03954 4.49e-130 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AFOFKEHG_03955 2.25e-157 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
AFOFKEHG_03956 3.67e-227 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AFOFKEHG_03957 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AFOFKEHG_03958 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AFOFKEHG_03959 4.16e-292 ybbR - - S - - - protein conserved in bacteria
AFOFKEHG_03960 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AFOFKEHG_03961 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
AFOFKEHG_03962 1.6e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
AFOFKEHG_03968 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
AFOFKEHG_03969 1.55e-114 ybbJ - - J - - - acetyltransferase
AFOFKEHG_03970 4.04e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AFOFKEHG_03971 3.82e-194 ybbH - - K - - - transcriptional
AFOFKEHG_03972 7.29e-304 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
AFOFKEHG_03973 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
AFOFKEHG_03974 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
AFOFKEHG_03975 3.6e-306 ybbC - - S - - - protein conserved in bacteria
AFOFKEHG_03976 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
AFOFKEHG_03977 9.23e-219 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
AFOFKEHG_03978 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFOFKEHG_03979 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFOFKEHG_03980 4.01e-184 ybbA - - S ko:K07017 - ko00000 Putative esterase
AFOFKEHG_03981 3.47e-205 ybaS - - S - - - Na -dependent transporter
AFOFKEHG_03983 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
AFOFKEHG_03984 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AFOFKEHG_03985 1.45e-93 ywhA - - K - - - Transcriptional regulator
AFOFKEHG_03986 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
AFOFKEHG_03987 5.45e-153 ywhC - - S - - - Peptidase family M50
AFOFKEHG_03988 5.51e-123 ywhD - - S - - - YwhD family
AFOFKEHG_03989 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
AFOFKEHG_03990 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AFOFKEHG_03991 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
AFOFKEHG_03992 6.61e-110 - - - S - - - Aminoacyl-tRNA editing domain
AFOFKEHG_03994 2.88e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
AFOFKEHG_03995 2.36e-291 ywhK - - CO - - - amine dehydrogenase activity
AFOFKEHG_03996 0.0 ywhL - - CO - - - amine dehydrogenase activity
AFOFKEHG_03998 0.0 - - - L - - - Peptidase, M16
AFOFKEHG_03999 7.55e-280 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
AFOFKEHG_04000 1.07e-300 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
AFOFKEHG_04001 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
AFOFKEHG_04003 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
AFOFKEHG_04004 3.71e-12 - - - S - - - Bacteriocin subtilosin A
AFOFKEHG_04005 4.64e-96 ywiB - - S - - - protein conserved in bacteria
AFOFKEHG_04006 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
AFOFKEHG_04007 1.2e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
AFOFKEHG_04008 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
AFOFKEHG_04009 1.84e-179 ywiC - - S - - - YwiC-like protein
AFOFKEHG_04010 7.13e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
AFOFKEHG_04011 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AFOFKEHG_04012 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
AFOFKEHG_04013 2.28e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
AFOFKEHG_04014 2.06e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
AFOFKEHG_04015 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFOFKEHG_04016 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
AFOFKEHG_04017 1.35e-124 ywjB - - H - - - RibD C-terminal domain
AFOFKEHG_04018 1.32e-57 ywjC - - - - - - -
AFOFKEHG_04019 4.88e-236 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
AFOFKEHG_04020 8.56e-290 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
AFOFKEHG_04021 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
AFOFKEHG_04022 3.48e-268 acdA - - I - - - acyl-CoA dehydrogenase
AFOFKEHG_04023 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AFOFKEHG_04024 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AFOFKEHG_04025 1.06e-116 ywjG - - S - - - Domain of unknown function (DUF2529)
AFOFKEHG_04026 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
AFOFKEHG_04027 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
AFOFKEHG_04028 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AFOFKEHG_04029 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AFOFKEHG_04030 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
AFOFKEHG_04031 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AFOFKEHG_04032 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
AFOFKEHG_04033 8.53e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
AFOFKEHG_04034 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
AFOFKEHG_04035 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
AFOFKEHG_04036 6.26e-119 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
AFOFKEHG_04037 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFOFKEHG_04038 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AFOFKEHG_04039 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AFOFKEHG_04041 1.67e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
AFOFKEHG_04042 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
AFOFKEHG_04043 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
AFOFKEHG_04044 4.44e-252 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AFOFKEHG_04045 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
AFOFKEHG_04046 5.75e-103 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AFOFKEHG_04047 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
AFOFKEHG_04048 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
AFOFKEHG_04049 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AFOFKEHG_04050 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AFOFKEHG_04051 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
AFOFKEHG_04052 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
AFOFKEHG_04053 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFOFKEHG_04054 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AFOFKEHG_04055 7.94e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFOFKEHG_04056 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AFOFKEHG_04057 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AFOFKEHG_04058 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AFOFKEHG_04059 1.04e-76 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
AFOFKEHG_04060 6.12e-115 ywmA - - - - - - -
AFOFKEHG_04061 4.54e-45 ywzB - - S - - - membrane
AFOFKEHG_04062 2.39e-174 ywmB - - S - - - TATA-box binding
AFOFKEHG_04063 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AFOFKEHG_04064 3.72e-238 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
AFOFKEHG_04065 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
AFOFKEHG_04066 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
AFOFKEHG_04068 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AFOFKEHG_04069 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AFOFKEHG_04070 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
AFOFKEHG_04071 1.12e-109 ywmF - - S - - - Peptidase M50
AFOFKEHG_04072 1.11e-21 csbD - - K - - - CsbD-like
AFOFKEHG_04074 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
AFOFKEHG_04075 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
AFOFKEHG_04076 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
AFOFKEHG_04077 4.58e-85 ywnA - - K - - - Transcriptional regulator
AFOFKEHG_04078 1.29e-148 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
AFOFKEHG_04079 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
AFOFKEHG_04080 3.41e-184 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
AFOFKEHG_04081 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFOFKEHG_04082 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
AFOFKEHG_04083 3.28e-22 ywnC - - S - - - Family of unknown function (DUF5362)
AFOFKEHG_04084 1.55e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
AFOFKEHG_04085 2.13e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
AFOFKEHG_04086 1.63e-95 ywnJ - - S - - - VanZ like family
AFOFKEHG_04087 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
AFOFKEHG_04088 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
AFOFKEHG_04089 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
AFOFKEHG_04090 4.15e-100 - - - - - - - -
AFOFKEHG_04091 2.56e-134 yjgF - - Q - - - Isochorismatase family
AFOFKEHG_04092 8e-309 ywoD - - EGP - - - Major facilitator superfamily
AFOFKEHG_04093 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
AFOFKEHG_04094 1.02e-312 ywoF - - P - - - Right handed beta helix region
AFOFKEHG_04095 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
AFOFKEHG_04096 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
AFOFKEHG_04097 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
AFOFKEHG_04098 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
AFOFKEHG_04099 6.18e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
AFOFKEHG_04100 4.1e-182 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
AFOFKEHG_04101 5.45e-257 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
AFOFKEHG_04102 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AFOFKEHG_04103 1.13e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AFOFKEHG_04104 2.55e-197 ywpD - - T - - - Histidine kinase
AFOFKEHG_04105 4.63e-68 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
AFOFKEHG_04106 8.81e-89 ywpF - - S - - - YwpF-like protein
AFOFKEHG_04107 5.26e-88 ywpG - - - - - - -
AFOFKEHG_04108 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
AFOFKEHG_04109 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
AFOFKEHG_04110 5.28e-202 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
AFOFKEHG_04111 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
AFOFKEHG_04112 0.0 ywqB - - S - - - SWIM zinc finger
AFOFKEHG_04113 3.6e-25 - - - - - - - -
AFOFKEHG_04114 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
AFOFKEHG_04115 4.51e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
AFOFKEHG_04116 3.16e-183 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
AFOFKEHG_04117 9.82e-315 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AFOFKEHG_04118 7.24e-197 ywqG - - S - - - Domain of unknown function (DUF1963)
AFOFKEHG_04120 8.84e-52 ywqI - - S - - - Family of unknown function (DUF5344)
AFOFKEHG_04121 3.35e-301 ywqJ - - S - - - Pre-toxin TG
AFOFKEHG_04123 2.92e-148 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
AFOFKEHG_04124 2.34e-209 - - - K - - - Transcriptional regulator
AFOFKEHG_04125 5.03e-128 ywqN - - S - - - NAD(P)H-dependent
AFOFKEHG_04127 3.66e-115 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
AFOFKEHG_04128 5.52e-133 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
AFOFKEHG_04129 4.83e-108 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
AFOFKEHG_04130 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
AFOFKEHG_04131 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
AFOFKEHG_04132 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AFOFKEHG_04133 2.17e-16 - - - - - - - -
AFOFKEHG_04134 1.12e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
AFOFKEHG_04135 5.9e-177 cotB - - - ko:K06325 - ko00000 -
AFOFKEHG_04136 3.04e-162 ywrJ - - - - - - -
AFOFKEHG_04137 9.73e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AFOFKEHG_04138 3.36e-218 alsR - - K - - - LysR substrate binding domain
AFOFKEHG_04139 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
AFOFKEHG_04140 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
AFOFKEHG_04141 8.76e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
AFOFKEHG_04142 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
AFOFKEHG_04143 1.97e-119 batE - - T - - - Sh3 type 3 domain protein
AFOFKEHG_04144 1.05e-202 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
AFOFKEHG_04145 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
AFOFKEHG_04146 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
AFOFKEHG_04147 3.24e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
AFOFKEHG_04148 7.52e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AFOFKEHG_04149 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
AFOFKEHG_04150 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
AFOFKEHG_04151 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
AFOFKEHG_04152 1.1e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
AFOFKEHG_04153 2.29e-29 ywtC - - - - - - -
AFOFKEHG_04154 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
AFOFKEHG_04155 4.69e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
AFOFKEHG_04156 2.86e-220 ywtF_2 - - K - - - Transcriptional regulator
AFOFKEHG_04157 2.27e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
AFOFKEHG_04158 1.95e-251 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
AFOFKEHG_04159 3.4e-238 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
AFOFKEHG_04160 3.12e-310 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
AFOFKEHG_04161 9.14e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
AFOFKEHG_04162 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AFOFKEHG_04163 8.52e-217 - - - - - - - -
AFOFKEHG_04164 5.15e-49 - - - - - - - -
AFOFKEHG_04165 4.43e-272 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AFOFKEHG_04166 1.9e-185 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
AFOFKEHG_04167 3.82e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
AFOFKEHG_04168 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
AFOFKEHG_04169 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AFOFKEHG_04170 2.06e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)