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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HECICMKH_00001	8.95e-315	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HECICMKH_00002	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HECICMKH_00003	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HECICMKH_00004	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HECICMKH_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HECICMKH_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HECICMKH_00007	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HECICMKH_00008	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HECICMKH_00009	1.68e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HECICMKH_00010	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HECICMKH_00011	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HECICMKH_00012	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HECICMKH_00013	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HECICMKH_00014	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HECICMKH_00015	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HECICMKH_00016	3.25e-292	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HECICMKH_00018	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HECICMKH_00020	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HECICMKH_00021	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HECICMKH_00022	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HECICMKH_00023	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HECICMKH_00024	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HECICMKH_00025	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HECICMKH_00027	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HECICMKH_00028	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HECICMKH_00029	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HECICMKH_00030	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HECICMKH_00031	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HECICMKH_00032	2.54e-50	-	-	-	-	-	-	-	-
HECICMKH_00034	1.56e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HECICMKH_00035	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HECICMKH_00036	3.55e-313	yycH	-	-	S	-	-	-	YycH protein
HECICMKH_00037	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HECICMKH_00038	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HECICMKH_00039	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HECICMKH_00040	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HECICMKH_00041	2e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_00042	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HECICMKH_00043	1.71e-156	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HECICMKH_00044	2.24e-155	pnb	-	-	C	-	-	-	nitroreductase
HECICMKH_00045	2.02e-85	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HECICMKH_00046	2.14e-148	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HECICMKH_00047	0.0	-	-	-	C	-	-	-	FMN_bind
HECICMKH_00048	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HECICMKH_00049	8.07e-202	-	-	-	K	-	-	-	LysR family
HECICMKH_00050	1.69e-93	-	-	-	C	-	-	-	FMN binding
HECICMKH_00051	1.82e-97	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HECICMKH_00052	3.34e-210	-	-	-	S	-	-	-	KR domain
HECICMKH_00053	9.51e-203	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HECICMKH_00054	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HECICMKH_00055	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HECICMKH_00056	2.22e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HECICMKH_00057	2.28e-250	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HECICMKH_00058	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HECICMKH_00059	6.86e-175	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HECICMKH_00060	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HECICMKH_00061	1.65e-106	-	-	-	S	-	-	-	ASCH
HECICMKH_00062	1.25e-164	-	-	-	F	-	-	-	glutamine amidotransferase
HECICMKH_00063	1.88e-216	-	-	-	K	-	-	-	WYL domain
HECICMKH_00064	6.65e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HECICMKH_00065	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HECICMKH_00066	3.66e-59	-	-	-	S	-	-	-	Protein of unknown function
HECICMKH_00067	2.84e-81	-	-	-	S	-	-	-	Protein of unknown function
HECICMKH_00068	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HECICMKH_00069	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HECICMKH_00070	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
HECICMKH_00071	3.42e-234	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HECICMKH_00072	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HECICMKH_00073	6.97e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HECICMKH_00074	3.5e-217	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HECICMKH_00075	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HECICMKH_00076	2.38e-99	-	-	-	-	-	-	-	-
HECICMKH_00077	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HECICMKH_00078	6.89e-180	-	-	-	-	-	-	-	-
HECICMKH_00079	4.07e-05	-	-	-	-	-	-	-	-
HECICMKH_00080	8.05e-186	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HECICMKH_00081	1.67e-54	-	-	-	-	-	-	-	-
HECICMKH_00082	8.65e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HECICMKH_00083	8.38e-193	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HECICMKH_00084	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HECICMKH_00085	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HECICMKH_00086	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HECICMKH_00087	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HECICMKH_00088	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HECICMKH_00089	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HECICMKH_00090	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HECICMKH_00091	5.24e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HECICMKH_00092	4.79e-225	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HECICMKH_00093	2.27e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HECICMKH_00094	1.13e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HECICMKH_00095	2.68e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HECICMKH_00096	9.14e-265	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HECICMKH_00097	7.45e-178	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HECICMKH_00098	0.0	-	-	-	L	-	-	-	HIRAN domain
HECICMKH_00099	1.24e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HECICMKH_00100	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HECICMKH_00101	8.96e-160	-	-	-	-	-	-	-	-
HECICMKH_00102	5.08e-192	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HECICMKH_00103	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HECICMKH_00104	1.29e-181	-	-	-	F	-	-	-	Phosphorylase superfamily
HECICMKH_00105	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HECICMKH_00106	2.09e-143	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HECICMKH_00107	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_00108	2.31e-95	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HECICMKH_00109	2.14e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HECICMKH_00110	4.14e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
HECICMKH_00111	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HECICMKH_00112	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HECICMKH_00113	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HECICMKH_00115	2.16e-204	morA	-	-	S	-	-	-	reductase
HECICMKH_00116	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HECICMKH_00117	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HECICMKH_00118	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HECICMKH_00119	4.03e-132	-	-	-	-	-	-	-	-
HECICMKH_00120	0.0	-	-	-	-	-	-	-	-
HECICMKH_00121	7.57e-267	-	-	-	C	-	-	-	Oxidoreductase
HECICMKH_00122	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HECICMKH_00123	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HECICMKH_00124	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HECICMKH_00125	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HECICMKH_00126	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HECICMKH_00127	7.71e-183	-	-	-	-	-	-	-	-
HECICMKH_00128	3.12e-126	-	-	-	-	-	-	-	-
HECICMKH_00129	2.85e-51	-	-	-	-	-	-	-	-
HECICMKH_00130	3.37e-115	-	-	-	-	-	-	-	-
HECICMKH_00131	2.91e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HECICMKH_00132	1.04e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HECICMKH_00133	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HECICMKH_00134	9.77e-152	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HECICMKH_00135	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HECICMKH_00136	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HECICMKH_00138	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_00139	1.36e-242	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HECICMKH_00140	9.52e-240	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HECICMKH_00141	2.75e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HECICMKH_00142	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HECICMKH_00143	4.67e-171	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HECICMKH_00144	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HECICMKH_00145	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HECICMKH_00146	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HECICMKH_00147	4.69e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECICMKH_00148	2.16e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECICMKH_00149	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HECICMKH_00150	1.75e-191	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HECICMKH_00151	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HECICMKH_00152	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HECICMKH_00153	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HECICMKH_00154	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HECICMKH_00155	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HECICMKH_00156	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HECICMKH_00157	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HECICMKH_00158	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HECICMKH_00159	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HECICMKH_00160	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HECICMKH_00161	9.92e-212	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HECICMKH_00162	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HECICMKH_00163	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HECICMKH_00164	9.92e-212	mleR	-	-	K	-	-	-	LysR substrate binding domain
HECICMKH_00165	0.0	-	-	-	M	-	-	-	domain protein
HECICMKH_00167	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HECICMKH_00168	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HECICMKH_00169	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HECICMKH_00170	1.31e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HECICMKH_00171	1.19e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HECICMKH_00172	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HECICMKH_00173	2.73e-147	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HECICMKH_00174	1.01e-228	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HECICMKH_00175	6.33e-46	-	-	-	-	-	-	-	-
HECICMKH_00176	4.69e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HECICMKH_00177	6.21e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HECICMKH_00178	2.6e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HECICMKH_00179	3.81e-18	-	-	-	-	-	-	-	-
HECICMKH_00180	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HECICMKH_00181	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HECICMKH_00182	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HECICMKH_00183	6.11e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HECICMKH_00184	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HECICMKH_00185	1.43e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HECICMKH_00186	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HECICMKH_00187	5.3e-202	dkgB	-	-	S	-	-	-	reductase
HECICMKH_00188	5.23e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HECICMKH_00189	1.2e-91	-	-	-	-	-	-	-	-
HECICMKH_00190	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HECICMKH_00191	1.05e-219	-	-	-	P	-	-	-	Major Facilitator Superfamily
HECICMKH_00192	2.37e-284	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HECICMKH_00193	7.43e-128	-	-	-	K	-	-	-	Helix-turn-helix domain
HECICMKH_00194	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HECICMKH_00195	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HECICMKH_00196	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HECICMKH_00197	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HECICMKH_00198	2.61e-282	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HECICMKH_00199	9.49e-109	-	-	-	-	-	-	-	-
HECICMKH_00200	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HECICMKH_00201	2.03e-124	-	-	-	-	-	-	-	-
HECICMKH_00202	2.98e-90	-	-	-	-	-	-	-	-
HECICMKH_00203	1.2e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HECICMKH_00204	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HECICMKH_00205	2.21e-127	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HECICMKH_00206	1.89e-159	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HECICMKH_00207	4.08e-291	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HECICMKH_00208	6.14e-53	-	-	-	-	-	-	-	-
HECICMKH_00209	7.59e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HECICMKH_00210	3.63e-271	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
HECICMKH_00211	5.06e-259	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
HECICMKH_00212	1.22e-166	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HECICMKH_00213	2.02e-245	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HECICMKH_00214	3.68e-125	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HECICMKH_00215	5.78e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HECICMKH_00216	1.3e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HECICMKH_00217	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HECICMKH_00218	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HECICMKH_00219	1.52e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HECICMKH_00220	2.21e-56	-	-	-	-	-	-	-	-
HECICMKH_00221	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HECICMKH_00222	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HECICMKH_00223	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HECICMKH_00224	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HECICMKH_00225	2.6e-185	-	-	-	-	-	-	-	-
HECICMKH_00226	6.2e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HECICMKH_00227	7.84e-92	-	-	-	-	-	-	-	-
HECICMKH_00228	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_00229	5.2e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_00230	4.02e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HECICMKH_00231	2.6e-149	-	-	-	-	-	-	-	-
HECICMKH_00232	2.81e-55	-	-	-	-	-	-	-	-
HECICMKH_00233	1.55e-55	-	-	-	-	-	-	-	-
HECICMKH_00234	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HECICMKH_00235	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HECICMKH_00236	1.4e-314	hpk2	-	-	T	-	-	-	Histidine kinase
HECICMKH_00237	1.56e-164	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HECICMKH_00238	2.42e-65	-	-	-	-	-	-	-	-
HECICMKH_00239	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HECICMKH_00240	1.81e-308	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HECICMKH_00241	3.35e-75	-	-	-	-	-	-	-	-
HECICMKH_00242	2.87e-56	-	-	-	-	-	-	-	-
HECICMKH_00243	2.92e-235	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HECICMKH_00244	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HECICMKH_00245	1.49e-63	-	-	-	-	-	-	-	-
HECICMKH_00246	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HECICMKH_00247	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HECICMKH_00248	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HECICMKH_00249	8.31e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HECICMKH_00250	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HECICMKH_00251	1.51e-294	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HECICMKH_00252	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HECICMKH_00253	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HECICMKH_00254	2.75e-156	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HECICMKH_00255	9.9e-75	-	-	-	M	-	-	-	Lysin motif
HECICMKH_00256	1.19e-88	-	-	-	M	-	-	-	LysM domain protein
HECICMKH_00257	9.91e-87	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HECICMKH_00258	4.47e-229	-	-	-	-	-	-	-	-
HECICMKH_00259	6.88e-170	-	-	-	-	-	-	-	-
HECICMKH_00260	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HECICMKH_00261	2.03e-75	-	-	-	-	-	-	-	-
HECICMKH_00262	9.17e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HECICMKH_00263	1.08e-101	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HECICMKH_00264	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_00265	1.17e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HECICMKH_00266	6.01e-51	-	-	-	-	-	-	-	-
HECICMKH_00268	7.37e-36	-	-	-	-	-	-	-	-
HECICMKH_00269	9.25e-32	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
HECICMKH_00270	5.3e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HECICMKH_00271	5.58e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HECICMKH_00272	9e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HECICMKH_00273	1.46e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HECICMKH_00274	1.5e-124	-	-	-	K	-	-	-	Cupin domain
HECICMKH_00275	8.08e-110	-	-	-	S	-	-	-	ASCH
HECICMKH_00276	3.12e-110	-	-	-	K	-	-	-	GNAT family
HECICMKH_00277	2.05e-115	-	-	-	K	-	-	-	acetyltransferase
HECICMKH_00278	2.06e-30	-	-	-	-	-	-	-	-
HECICMKH_00279	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HECICMKH_00280	1.52e-207	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HECICMKH_00281	3.6e-242	-	-	-	-	-	-	-	-
HECICMKH_00282	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HECICMKH_00283	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HECICMKH_00284	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HECICMKH_00285	6.77e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HECICMKH_00286	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HECICMKH_00287	7.28e-42	-	-	-	-	-	-	-	-
HECICMKH_00288	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HECICMKH_00289	6.4e-54	-	-	-	-	-	-	-	-
HECICMKH_00290	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HECICMKH_00291	1.49e-227	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HECICMKH_00292	2e-81	-	-	-	S	-	-	-	CHY zinc finger
HECICMKH_00293	9.4e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HECICMKH_00294	4.5e-280	-	-	-	-	-	-	-	-
HECICMKH_00295	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HECICMKH_00296	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HECICMKH_00297	3.93e-59	-	-	-	-	-	-	-	-
HECICMKH_00298	2.24e-112	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HECICMKH_00299	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HECICMKH_00300	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HECICMKH_00301	2.21e-227	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HECICMKH_00302	8.95e-60	-	-	-	-	-	-	-	-
HECICMKH_00303	1.05e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HECICMKH_00304	1.44e-154	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HECICMKH_00305	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HECICMKH_00306	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HECICMKH_00307	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HECICMKH_00308	1.96e-295	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HECICMKH_00309	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HECICMKH_00310	1.52e-103	-	-	-	-	-	-	-	-
HECICMKH_00311	2.43e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HECICMKH_00312	3.66e-224	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HECICMKH_00313	4.01e-206	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HECICMKH_00314	1.94e-100	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HECICMKH_00315	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HECICMKH_00316	1.1e-229	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_00317	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HECICMKH_00318	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HECICMKH_00319	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HECICMKH_00320	2.5e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HECICMKH_00321	0.0	-	-	-	M	-	-	-	domain protein
HECICMKH_00322	2.45e-88	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
HECICMKH_00323	7.13e-54	-	-	-	-	-	-	-	-
HECICMKH_00324	2.85e-53	-	-	-	-	-	-	-	-
HECICMKH_00326	3.15e-229	-	-	-	-	-	-	-	-
HECICMKH_00327	1.24e-11	-	-	-	S	-	-	-	Immunity protein 22
HECICMKH_00328	5.89e-131	-	-	-	S	-	-	-	ankyrin repeats
HECICMKH_00329	3.31e-52	-	-	-	-	-	-	-	-
HECICMKH_00330	8.53e-28	-	-	-	-	-	-	-	-
HECICMKH_00331	5.52e-64	-	-	-	U	-	-	-	nuclease activity
HECICMKH_00332	5.89e-90	-	-	-	-	-	-	-	-
HECICMKH_00333	3.47e-90	-	-	-	S	-	-	-	Immunity protein 63
HECICMKH_00334	9.91e-17	-	-	-	L	-	-	-	LXG domain of WXG superfamily
HECICMKH_00335	8.5e-55	-	-	-	-	-	-	-	-
HECICMKH_00336	4.56e-154	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HECICMKH_00337	1.29e-261	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HECICMKH_00338	2.3e-185	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HECICMKH_00339	2.35e-212	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_00340	8.38e-192	-	-	-	S	-	-	-	hydrolase
HECICMKH_00341	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HECICMKH_00342	8.8e-265	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HECICMKH_00344	1.15e-43	-	-	-	-	-	-	-	-
HECICMKH_00345	6.24e-25	plnR	-	-	-	-	-	-	-
HECICMKH_00346	9.76e-153	-	-	-	-	-	-	-	-
HECICMKH_00347	3.29e-32	plnK	-	-	-	-	-	-	-
HECICMKH_00348	8.53e-34	plnJ	-	-	-	-	-	-	-
HECICMKH_00349	4.08e-39	-	-	-	-	-	-	-	-
HECICMKH_00351	5.58e-291	-	-	-	M	-	-	-	Glycosyl transferase family 2
HECICMKH_00352	2.08e-160	plnP	-	-	S	-	-	-	CAAX protease self-immunity
HECICMKH_00353	1.22e-36	-	-	-	-	-	-	-	-
HECICMKH_00354	1.9e-25	plnA	-	-	-	-	-	-	-
HECICMKH_00355	2.08e-301	plnB	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HECICMKH_00356	2.48e-172	sppR	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HECICMKH_00357	1.05e-173	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HECICMKH_00358	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HECICMKH_00359	1.93e-31	plnF	-	-	-	-	-	-	-
HECICMKH_00360	8.82e-32	-	-	-	-	-	-	-	-
HECICMKH_00361	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HECICMKH_00362	1.49e-309	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HECICMKH_00363	3.26e-124	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HECICMKH_00364	5.04e-155	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HECICMKH_00365	2.75e-145	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HECICMKH_00366	3.34e-147	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HECICMKH_00367	1.85e-40	-	-	-	-	-	-	-	-
HECICMKH_00368	0.0	-	-	-	L	-	-	-	DNA helicase
HECICMKH_00369	1.38e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HECICMKH_00370	8.19e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HECICMKH_00371	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HECICMKH_00372	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HECICMKH_00373	9.68e-34	-	-	-	-	-	-	-	-
HECICMKH_00374	3.55e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HECICMKH_00375	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HECICMKH_00376	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HECICMKH_00377	6.97e-209	-	-	-	GK	-	-	-	ROK family
HECICMKH_00378	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HECICMKH_00379	8.42e-244	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HECICMKH_00380	1.23e-262	-	-	-	-	-	-	-	-
HECICMKH_00381	5.08e-194	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HECICMKH_00382	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HECICMKH_00383	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HECICMKH_00384	4.65e-229	-	-	-	-	-	-	-	-
HECICMKH_00385	8.73e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HECICMKH_00386	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HECICMKH_00387	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HECICMKH_00388	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HECICMKH_00389	4.08e-270	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HECICMKH_00390	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HECICMKH_00391	3.1e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HECICMKH_00392	1.02e-202	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HECICMKH_00393	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HECICMKH_00394	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HECICMKH_00395	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HECICMKH_00396	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HECICMKH_00397	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HECICMKH_00398	2.4e-56	-	-	-	S	-	-	-	ankyrin repeats
HECICMKH_00399	5.3e-49	-	-	-	-	-	-	-	-
HECICMKH_00400	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HECICMKH_00401	3.28e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HECICMKH_00402	1.1e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HECICMKH_00403	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HECICMKH_00404	1.15e-235	-	-	-	S	-	-	-	DUF218 domain
HECICMKH_00405	4.31e-179	-	-	-	-	-	-	-	-
HECICMKH_00406	4.15e-191	yxeH	-	-	S	-	-	-	hydrolase
HECICMKH_00407	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HECICMKH_00408	8.97e-200	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HECICMKH_00409	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HECICMKH_00410	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HECICMKH_00411	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HECICMKH_00412	2.66e-308	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HECICMKH_00413	1.32e-289	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HECICMKH_00414	1.52e-158	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HECICMKH_00415	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HECICMKH_00416	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
HECICMKH_00417	4.01e-36	-	-	-	-	-	-	-	-
HECICMKH_00418	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HECICMKH_00419	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HECICMKH_00420	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HECICMKH_00421	1.05e-273	-	-	-	J	-	-	-	translation release factor activity
HECICMKH_00422	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HECICMKH_00423	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HECICMKH_00424	4.58e-194	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HECICMKH_00425	1.84e-189	-	-	-	-	-	-	-	-
HECICMKH_00426	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HECICMKH_00427	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HECICMKH_00428	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HECICMKH_00429	5e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HECICMKH_00430	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HECICMKH_00431	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HECICMKH_00432	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HECICMKH_00433	1.06e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECICMKH_00434	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HECICMKH_00435	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HECICMKH_00436	3.7e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HECICMKH_00437	6.25e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HECICMKH_00438	1.38e-293	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HECICMKH_00439	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HECICMKH_00440	1.9e-277	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HECICMKH_00441	2.16e-240	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HECICMKH_00442	5.3e-110	queT	-	-	S	-	-	-	QueT transporter
HECICMKH_00443	5.29e-211	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HECICMKH_00444	8.1e-157	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HECICMKH_00445	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
HECICMKH_00446	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HECICMKH_00447	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HECICMKH_00448	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HECICMKH_00449	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HECICMKH_00450	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HECICMKH_00451	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HECICMKH_00453	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HECICMKH_00454	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HECICMKH_00455	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HECICMKH_00456	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HECICMKH_00457	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HECICMKH_00458	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HECICMKH_00459	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HECICMKH_00460	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HECICMKH_00463	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HECICMKH_00466	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HECICMKH_00467	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HECICMKH_00471	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HECICMKH_00472	2.78e-71	-	-	-	S	-	-	-	Cupin domain
HECICMKH_00473	1.31e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HECICMKH_00474	6.2e-245	ysdE	-	-	P	-	-	-	Citrate transporter
HECICMKH_00475	5.35e-187	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HECICMKH_00476	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HECICMKH_00477	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HECICMKH_00478	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HECICMKH_00479	6.62e-176	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HECICMKH_00480	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HECICMKH_00481	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HECICMKH_00482	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HECICMKH_00483	2.57e-94	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HECICMKH_00484	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HECICMKH_00485	3.62e-105	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HECICMKH_00486	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HECICMKH_00487	1.19e-201	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HECICMKH_00489	1e-200	-	-	-	G	-	-	-	Peptidase_C39 like family
HECICMKH_00490	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HECICMKH_00491	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HECICMKH_00492	1.87e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HECICMKH_00493	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HECICMKH_00494	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HECICMKH_00495	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HECICMKH_00496	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HECICMKH_00497	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HECICMKH_00498	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HECICMKH_00499	4.82e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HECICMKH_00500	6.33e-185	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HECICMKH_00501	1.23e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HECICMKH_00502	2.9e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HECICMKH_00503	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HECICMKH_00504	6.04e-227	-	-	-	EG	-	-	-	EamA-like transporter family
HECICMKH_00505	3.3e-166	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HECICMKH_00506	4.57e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HECICMKH_00507	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HECICMKH_00508	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HECICMKH_00509	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HECICMKH_00510	3.29e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HECICMKH_00511	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HECICMKH_00512	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HECICMKH_00513	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HECICMKH_00514	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HECICMKH_00515	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HECICMKH_00516	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HECICMKH_00517	5.87e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HECICMKH_00518	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HECICMKH_00519	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HECICMKH_00520	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HECICMKH_00521	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HECICMKH_00522	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HECICMKH_00523	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HECICMKH_00524	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HECICMKH_00525	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HECICMKH_00526	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HECICMKH_00527	1.31e-211	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HECICMKH_00528	4.16e-87	-	-	-	L	-	-	-	nuclease
HECICMKH_00529	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HECICMKH_00530	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HECICMKH_00531	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HECICMKH_00532	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HECICMKH_00533	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HECICMKH_00534	1.58e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HECICMKH_00535	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HECICMKH_00536	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HECICMKH_00537	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HECICMKH_00538	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HECICMKH_00539	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HECICMKH_00540	6.36e-153	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HECICMKH_00541	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HECICMKH_00542	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HECICMKH_00543	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HECICMKH_00544	1.53e-212	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HECICMKH_00545	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HECICMKH_00546	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HECICMKH_00547	8.87e-269	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HECICMKH_00548	1.97e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HECICMKH_00549	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HECICMKH_00550	2.65e-177	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HECICMKH_00551	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HECICMKH_00552	2.84e-241	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HECICMKH_00553	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HECICMKH_00554	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HECICMKH_00555	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HECICMKH_00556	7.63e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HECICMKH_00557	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HECICMKH_00558	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HECICMKH_00559	1.68e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HECICMKH_00560	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HECICMKH_00561	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HECICMKH_00562	0.0	ydaO	-	-	E	-	-	-	amino acid
HECICMKH_00563	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HECICMKH_00564	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HECICMKH_00565	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HECICMKH_00566	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HECICMKH_00567	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HECICMKH_00568	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HECICMKH_00569	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HECICMKH_00570	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HECICMKH_00571	1.69e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HECICMKH_00572	5.22e-276	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HECICMKH_00573	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HECICMKH_00574	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HECICMKH_00575	6.91e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HECICMKH_00576	2.22e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HECICMKH_00577	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HECICMKH_00578	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HECICMKH_00579	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HECICMKH_00580	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HECICMKH_00581	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HECICMKH_00582	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HECICMKH_00583	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HECICMKH_00584	1.04e-211	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HECICMKH_00585	1.15e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HECICMKH_00586	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HECICMKH_00587	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HECICMKH_00588	0.0	nox	-	-	C	-	-	-	NADH oxidase
HECICMKH_00589	3.69e-206	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HECICMKH_00590	2.45e-310	-	-	-	-	-	-	-	-
HECICMKH_00591	8.36e-257	-	-	-	S	-	-	-	Protein conserved in bacteria
HECICMKH_00592	2.74e-277	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HECICMKH_00593	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HECICMKH_00594	7.91e-172	-	-	-	T	-	-	-	diguanylate cyclase activity
HECICMKH_00595	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HECICMKH_00596	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HECICMKH_00597	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HECICMKH_00598	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HECICMKH_00599	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HECICMKH_00600	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HECICMKH_00601	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HECICMKH_00602	8.83e-267	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HECICMKH_00603	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HECICMKH_00604	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HECICMKH_00605	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HECICMKH_00606	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HECICMKH_00607	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HECICMKH_00608	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HECICMKH_00609	6.07e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HECICMKH_00610	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HECICMKH_00611	4.56e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HECICMKH_00612	7e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HECICMKH_00613	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HECICMKH_00614	6.3e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HECICMKH_00615	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HECICMKH_00617	9.37e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HECICMKH_00618	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HECICMKH_00619	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HECICMKH_00620	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HECICMKH_00621	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HECICMKH_00622	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HECICMKH_00623	5.11e-171	-	-	-	-	-	-	-	-
HECICMKH_00624	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HECICMKH_00625	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HECICMKH_00626	6.62e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HECICMKH_00627	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HECICMKH_00628	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HECICMKH_00629	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HECICMKH_00630	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HECICMKH_00631	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HECICMKH_00632	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HECICMKH_00633	6.57e-136	-	-	-	-	-	-	-	-
HECICMKH_00634	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HECICMKH_00635	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HECICMKH_00636	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HECICMKH_00637	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HECICMKH_00638	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HECICMKH_00639	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HECICMKH_00640	1.03e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HECICMKH_00641	1.71e-210	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HECICMKH_00642	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HECICMKH_00643	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HECICMKH_00644	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HECICMKH_00645	5.68e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HECICMKH_00646	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HECICMKH_00647	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HECICMKH_00648	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HECICMKH_00649	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HECICMKH_00650	3.15e-158	-	-	-	T	-	-	-	EAL domain
HECICMKH_00651	9.79e-191	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HECICMKH_00652	4.93e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_00653	1.98e-261	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HECICMKH_00654	3.38e-70	-	-	-	-	-	-	-	-
HECICMKH_00655	2.49e-95	-	-	-	-	-	-	-	-
HECICMKH_00656	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HECICMKH_00657	7.34e-180	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HECICMKH_00658	1.74e-40	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HECICMKH_00659	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HECICMKH_00660	4.13e-182	-	-	-	-	-	-	-	-
HECICMKH_00662	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HECICMKH_00663	3.88e-46	-	-	-	-	-	-	-	-
HECICMKH_00664	3.45e-116	-	-	-	V	-	-	-	VanZ like family
HECICMKH_00665	1.06e-314	-	-	-	EGP	-	-	-	Major Facilitator
HECICMKH_00666	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HECICMKH_00667	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HECICMKH_00668	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HECICMKH_00669	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HECICMKH_00670	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_00671	1.36e-27	-	-	-	-	-	-	-	-
HECICMKH_00672	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HECICMKH_00673	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HECICMKH_00674	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HECICMKH_00675	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HECICMKH_00676	1.06e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HECICMKH_00677	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HECICMKH_00678	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HECICMKH_00679	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HECICMKH_00680	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
HECICMKH_00681	1.09e-60	-	-	-	-	-	-	-	-
HECICMKH_00682	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HECICMKH_00683	6.12e-115	-	-	-	-	-	-	-	-
HECICMKH_00684	7.76e-193	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HECICMKH_00685	3.05e-95	-	-	-	F	-	-	-	Nudix hydrolase
HECICMKH_00686	1.48e-27	-	-	-	-	-	-	-	-
HECICMKH_00687	7.32e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HECICMKH_00688	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HECICMKH_00689	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HECICMKH_00690	1.01e-188	-	-	-	-	-	-	-	-
HECICMKH_00691	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HECICMKH_00692	1.86e-267	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HECICMKH_00693	5.1e-218	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HECICMKH_00694	1.28e-54	-	-	-	-	-	-	-	-
HECICMKH_00696	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HECICMKH_00697	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HECICMKH_00698	1.81e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HECICMKH_00699	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HECICMKH_00700	1e-107	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HECICMKH_00701	1.34e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HECICMKH_00702	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HECICMKH_00703	1.24e-179	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HECICMKH_00704	8.73e-315	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HECICMKH_00705	2.55e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HECICMKH_00706	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HECICMKH_00707	3.08e-93	-	-	-	K	-	-	-	MarR family
HECICMKH_00708	8.85e-267	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HECICMKH_00709	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HECICMKH_00710	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_00711	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HECICMKH_00712	1.88e-101	rppH3	-	-	F	-	-	-	NUDIX domain
HECICMKH_00713	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HECICMKH_00714	1.61e-36	-	-	-	-	-	-	-	-
HECICMKH_00715	2.23e-164	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HECICMKH_00716	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HECICMKH_00717	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HECICMKH_00718	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HECICMKH_00719	2.84e-146	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HECICMKH_00720	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HECICMKH_00721	2.95e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HECICMKH_00722	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HECICMKH_00723	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HECICMKH_00725	3.56e-171	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
HECICMKH_00727	4.77e-48	-	-	-	L	-	-	-	Helix-turn-helix domain
HECICMKH_00728	1.51e-22	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HECICMKH_00729	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HECICMKH_00730	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HECICMKH_00731	1.38e-75	-	-	-	-	-	-	-	-
HECICMKH_00732	1.08e-71	-	-	-	-	-	-	-	-
HECICMKH_00733	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
HECICMKH_00734	1.16e-142	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HECICMKH_00735	3.08e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HECICMKH_00736	1.92e-301	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HECICMKH_00737	3.5e-299	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HECICMKH_00738	3.61e-61	-	-	-	S	-	-	-	MORN repeat
HECICMKH_00739	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HECICMKH_00740	7.38e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HECICMKH_00741	1.95e-116	-	-	-	-	-	-	-	-
HECICMKH_00742	5.74e-32	-	-	-	-	-	-	-	-
HECICMKH_00743	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HECICMKH_00744	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HECICMKH_00745	1.59e-189	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HECICMKH_00746	4.25e-211	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HECICMKH_00747	5.21e-62	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HECICMKH_00748	8.64e-83	-	-	-	G	-	-	-	Glycogen debranching enzyme
HECICMKH_00749	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HECICMKH_00750	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HECICMKH_00751	3.37e-60	-	-	-	S	-	-	-	MazG-like family
HECICMKH_00752	2.31e-117	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HECICMKH_00753	0.0	-	-	-	M	-	-	-	MucBP domain
HECICMKH_00754	1.42e-08	-	-	-	-	-	-	-	-
HECICMKH_00755	1.27e-115	-	-	-	S	-	-	-	AAA domain
HECICMKH_00756	7.45e-180	-	-	-	K	-	-	-	sequence-specific DNA binding
HECICMKH_00757	1.09e-123	-	-	-	K	-	-	-	Helix-turn-helix domain
HECICMKH_00758	1.6e-219	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_00759	0.0	-	-	-	C	-	-	-	FMN_bind
HECICMKH_00761	3.54e-105	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_00762	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HECICMKH_00763	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HECICMKH_00764	2.78e-254	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HECICMKH_00765	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HECICMKH_00766	1.32e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HECICMKH_00767	5.44e-56	-	-	-	-	-	-	-	-
HECICMKH_00768	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HECICMKH_00769	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HECICMKH_00770	1.36e-208	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HECICMKH_00771	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HECICMKH_00772	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HECICMKH_00773	1.12e-243	-	-	-	-	-	-	-	-
HECICMKH_00774	3.28e-278	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HECICMKH_00775	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HECICMKH_00776	4.77e-130	-	-	-	K	-	-	-	FR47-like protein
HECICMKH_00777	1.76e-155	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HECICMKH_00778	7.32e-247	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HECICMKH_00779	0.0	xylP2	-	-	G	-	-	-	symporter
HECICMKH_00780	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HECICMKH_00781	1.2e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HECICMKH_00782	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HECICMKH_00783	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HECICMKH_00784	4.09e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
HECICMKH_00785	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HECICMKH_00786	8.41e-170	-	-	-	-	-	-	-	-
HECICMKH_00787	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HECICMKH_00788	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HECICMKH_00789	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HECICMKH_00790	1.36e-77	-	-	-	-	-	-	-	-
HECICMKH_00791	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HECICMKH_00792	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HECICMKH_00793	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HECICMKH_00794	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HECICMKH_00795	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HECICMKH_00796	2.05e-153	-	-	-	I	-	-	-	phosphatase
HECICMKH_00797	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HECICMKH_00798	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HECICMKH_00799	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_00800	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HECICMKH_00801	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HECICMKH_00802	1.06e-152	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HECICMKH_00803	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HECICMKH_00804	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HECICMKH_00805	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HECICMKH_00813	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HECICMKH_00814	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HECICMKH_00815	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_00816	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HECICMKH_00817	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HECICMKH_00818	8.58e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HECICMKH_00819	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HECICMKH_00820	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HECICMKH_00821	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HECICMKH_00822	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HECICMKH_00823	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HECICMKH_00824	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HECICMKH_00825	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HECICMKH_00826	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HECICMKH_00827	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HECICMKH_00828	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HECICMKH_00829	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HECICMKH_00830	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HECICMKH_00831	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HECICMKH_00832	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HECICMKH_00833	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HECICMKH_00834	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HECICMKH_00835	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HECICMKH_00836	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HECICMKH_00837	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HECICMKH_00838	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HECICMKH_00839	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HECICMKH_00840	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HECICMKH_00841	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HECICMKH_00842	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HECICMKH_00843	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HECICMKH_00844	1.19e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HECICMKH_00845	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HECICMKH_00846	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HECICMKH_00847	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HECICMKH_00848	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HECICMKH_00849	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HECICMKH_00850	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HECICMKH_00851	5.37e-112	-	-	-	S	-	-	-	NusG domain II
HECICMKH_00852	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HECICMKH_00853	9.15e-194	-	-	-	S	-	-	-	FMN_bind
HECICMKH_00854	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HECICMKH_00855	1.63e-196	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HECICMKH_00856	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HECICMKH_00857	2.39e-184	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HECICMKH_00858	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HECICMKH_00859	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HECICMKH_00860	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HECICMKH_00861	8.51e-210	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HECICMKH_00862	7.05e-235	-	-	-	S	-	-	-	Membrane
HECICMKH_00863	1.35e-261	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HECICMKH_00864	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HECICMKH_00865	2.45e-213	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HECICMKH_00866	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HECICMKH_00867	3.51e-251	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HECICMKH_00868	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HECICMKH_00869	1.76e-68	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HECICMKH_00870	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HECICMKH_00871	5.21e-226	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HECICMKH_00872	6.07e-252	-	-	-	K	-	-	-	Helix-turn-helix domain
HECICMKH_00873	4.49e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HECICMKH_00874	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HECICMKH_00875	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HECICMKH_00876	5.19e-223	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HECICMKH_00877	1.18e-66	-	-	-	-	-	-	-	-
HECICMKH_00878	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HECICMKH_00879	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HECICMKH_00880	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HECICMKH_00881	3.88e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HECICMKH_00882	5.31e-242	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HECICMKH_00883	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HECICMKH_00884	3.32e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HECICMKH_00885	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HECICMKH_00886	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HECICMKH_00887	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HECICMKH_00888	2.32e-121	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HECICMKH_00889	2.62e-206	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HECICMKH_00890	6.5e-215	mleR	-	-	K	-	-	-	LysR family
HECICMKH_00891	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HECICMKH_00892	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HECICMKH_00893	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HECICMKH_00894	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HECICMKH_00895	2.56e-34	-	-	-	-	-	-	-	-
HECICMKH_00896	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HECICMKH_00897	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HECICMKH_00898	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HECICMKH_00899	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HECICMKH_00900	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HECICMKH_00901	2.68e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HECICMKH_00902	2.11e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HECICMKH_00903	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HECICMKH_00904	6.39e-234	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HECICMKH_00905	9.78e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HECICMKH_00906	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HECICMKH_00907	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HECICMKH_00908	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HECICMKH_00909	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HECICMKH_00910	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HECICMKH_00911	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
HECICMKH_00912	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HECICMKH_00913	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HECICMKH_00914	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HECICMKH_00915	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HECICMKH_00916	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HECICMKH_00917	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_00918	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HECICMKH_00919	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HECICMKH_00920	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HECICMKH_00921	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
HECICMKH_00922	7.76e-186	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HECICMKH_00923	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HECICMKH_00924	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HECICMKH_00925	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HECICMKH_00926	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HECICMKH_00928	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HECICMKH_00929	5.73e-316	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HECICMKH_00930	1.93e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HECICMKH_00932	7.62e-97	-	-	-	-	-	-	-	-
HECICMKH_00933	2.9e-139	-	-	-	-	-	-	-	-
HECICMKH_00934	4.73e-206	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HECICMKH_00935	2.22e-169	-	-	-	L	-	-	-	Helix-turn-helix domain
HECICMKH_00936	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HECICMKH_00937	1.63e-254	pbpX	-	-	V	-	-	-	Beta-lactamase
HECICMKH_00938	4.75e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HECICMKH_00939	7.42e-202	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HECICMKH_00940	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HECICMKH_00941	1.19e-258	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HECICMKH_00943	2.46e-25	-	-	-	D	-	-	-	protein tyrosine kinase activity
HECICMKH_00945	1.74e-110	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HECICMKH_00946	8.1e-99	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HECICMKH_00947	6.67e-23	yibD	-	GT2	M	ko:K19354	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferases involved in cell wall biogenesis
HECICMKH_00948	3.84e-95	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
HECICMKH_00949	5.93e-109	-	-	-	P	ko:K19419	-	ko00000,ko02000	EpsG family
HECICMKH_00950	1.39e-97	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HECICMKH_00951	1.92e-222	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HECICMKH_00952	4.83e-209	cps3D	-	-	-	-	-	-	-
HECICMKH_00953	1.45e-145	cps3E	-	-	-	-	-	-	-
HECICMKH_00954	1.41e-206	cps3F	-	-	-	-	-	-	-
HECICMKH_00955	5.72e-262	cps3H	-	-	-	-	-	-	-
HECICMKH_00956	2.31e-256	cps3I	-	-	G	-	-	-	Acyltransferase family
HECICMKH_00957	2.94e-190	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HECICMKH_00958	6.86e-175	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HECICMKH_00959	0.0	-	-	-	M	-	-	-	domain protein
HECICMKH_00960	5.36e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HECICMKH_00961	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HECICMKH_00962	1.38e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HECICMKH_00963	9.02e-70	-	-	-	-	-	-	-	-
HECICMKH_00964	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HECICMKH_00965	1.95e-41	-	-	-	-	-	-	-	-
HECICMKH_00966	1.35e-34	-	-	-	-	-	-	-	-
HECICMKH_00967	6.87e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HECICMKH_00968	1.9e-168	-	-	-	-	-	-	-	-
HECICMKH_00969	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HECICMKH_00970	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HECICMKH_00971	4.09e-172	lytE	-	-	M	-	-	-	NlpC/P60 family
HECICMKH_00972	8.01e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HECICMKH_00973	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HECICMKH_00974	1.3e-166	pbpX	-	-	V	-	-	-	Beta-lactamase
HECICMKH_00975	7.3e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HECICMKH_00976	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HECICMKH_00977	2.46e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HECICMKH_00978	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HECICMKH_00979	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HECICMKH_00980	3.36e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HECICMKH_00981	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HECICMKH_00982	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HECICMKH_00983	0.0	-	-	-	-	-	-	-	-
HECICMKH_00984	1.49e-252	-	-	-	M	-	-	-	MucBP domain
HECICMKH_00985	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HECICMKH_00986	2.03e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HECICMKH_00987	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HECICMKH_00988	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HECICMKH_00989	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HECICMKH_00990	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HECICMKH_00991	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HECICMKH_00992	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HECICMKH_00993	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HECICMKH_00994	2.5e-132	-	-	-	L	-	-	-	Integrase
HECICMKH_00995	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HECICMKH_00996	5.6e-41	-	-	-	-	-	-	-	-
HECICMKH_00997	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HECICMKH_00998	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HECICMKH_00999	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HECICMKH_01000	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HECICMKH_01001	8.79e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HECICMKH_01002	1.91e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HECICMKH_01003	1.66e-290	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HECICMKH_01004	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HECICMKH_01005	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HECICMKH_01008	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HECICMKH_01020	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HECICMKH_01021	1.28e-236	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HECICMKH_01022	1.25e-124	-	-	-	-	-	-	-	-
HECICMKH_01023	9.14e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HECICMKH_01024	1.46e-200	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HECICMKH_01027	3.8e-292	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HECICMKH_01028	2.95e-239	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HECICMKH_01029	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HECICMKH_01030	7.89e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HECICMKH_01031	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HECICMKH_01032	5.79e-158	-	-	-	-	-	-	-	-
HECICMKH_01033	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HECICMKH_01034	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HECICMKH_01035	1.2e-305	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HECICMKH_01036	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HECICMKH_01037	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HECICMKH_01038	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HECICMKH_01039	1.88e-39	-	-	-	-	-	-	-	-
HECICMKH_01040	3.54e-121	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HECICMKH_01041	3.58e-161	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HECICMKH_01042	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HECICMKH_01043	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HECICMKH_01044	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HECICMKH_01045	5.24e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HECICMKH_01046	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HECICMKH_01047	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HECICMKH_01048	1.24e-259	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HECICMKH_01049	3.93e-222	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECICMKH_01050	1.24e-192	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HECICMKH_01051	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECICMKH_01052	5.45e-162	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HECICMKH_01053	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HECICMKH_01054	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HECICMKH_01055	1.48e-315	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HECICMKH_01057	1.72e-162	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HECICMKH_01058	7.2e-200	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HECICMKH_01059	1.49e-225	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HECICMKH_01061	9.49e-196	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HECICMKH_01062	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HECICMKH_01063	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HECICMKH_01064	1.27e-202	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HECICMKH_01065	5.25e-258	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HECICMKH_01066	1.52e-207	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
HECICMKH_01067	2.56e-95	-	-	-	S	-	-	-	macrophage migration inhibitory factor
HECICMKH_01068	1.19e-280	-	-	-	C	-	-	-	Oxidoreductase
HECICMKH_01069	3.88e-203	-	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HECICMKH_01070	2.76e-87	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HECICMKH_01071	5.66e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HECICMKH_01072	1.3e-138	-	-	-	-	-	-	-	-
HECICMKH_01073	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HECICMKH_01074	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HECICMKH_01075	5.37e-74	-	-	-	-	-	-	-	-
HECICMKH_01076	4.56e-78	-	-	-	-	-	-	-	-
HECICMKH_01077	1.06e-146	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HECICMKH_01078	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HECICMKH_01079	8.82e-119	-	-	-	-	-	-	-	-
HECICMKH_01080	7.12e-62	-	-	-	-	-	-	-	-
HECICMKH_01081	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HECICMKH_01084	4.29e-87	-	-	-	-	-	-	-	-
HECICMKH_01085	9.03e-16	-	-	-	-	-	-	-	-
HECICMKH_01086	3.89e-237	-	-	-	-	-	-	-	-
HECICMKH_01087	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HECICMKH_01088	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HECICMKH_01089	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HECICMKH_01090	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HECICMKH_01091	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HECICMKH_01092	5.16e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HECICMKH_01093	9.14e-146	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HECICMKH_01094	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HECICMKH_01095	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HECICMKH_01096	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HECICMKH_01097	2.69e-316	dinF	-	-	V	-	-	-	MatE
HECICMKH_01098	1.79e-42	-	-	-	-	-	-	-	-
HECICMKH_01101	3.48e-103	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HECICMKH_01102	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HECICMKH_01103	4.64e-106	-	-	-	-	-	-	-	-
HECICMKH_01104	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HECICMKH_01105	6.25e-138	-	-	-	-	-	-	-	-
HECICMKH_01106	0.0	celR	-	-	K	-	-	-	PRD domain
HECICMKH_01107	2.7e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HECICMKH_01108	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HECICMKH_01109	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HECICMKH_01110	1.5e-310	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HECICMKH_01111	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HECICMKH_01112	1.28e-263	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HECICMKH_01113	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HECICMKH_01114	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HECICMKH_01115	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HECICMKH_01116	3.29e-132	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HECICMKH_01117	2.77e-271	arcT	-	-	E	-	-	-	Aminotransferase
HECICMKH_01118	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HECICMKH_01119	2.43e-18	-	-	-	-	-	-	-	-
HECICMKH_01120	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HECICMKH_01121	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HECICMKH_01122	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HECICMKH_01123	0.0	yhaN	-	-	L	-	-	-	AAA domain
HECICMKH_01124	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HECICMKH_01125	1.27e-121	-	-	-	-	-	-	-	-
HECICMKH_01126	9.16e-134	-	-	-	-	-	-	-	-
HECICMKH_01127	1.39e-232	-	-	-	M	-	-	-	Peptidase family S41
HECICMKH_01128	2.68e-226	-	-	-	K	-	-	-	LysR substrate binding domain
HECICMKH_01129	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HECICMKH_01130	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HECICMKH_01131	3e-127	-	-	-	-	-	-	-	-
HECICMKH_01132	2.76e-99	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HECICMKH_01133	5.27e-203	-	-	-	T	-	-	-	Histidine kinase
HECICMKH_01134	1.73e-134	llrE	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HECICMKH_01135	7.93e-79	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
HECICMKH_01136	2.26e-167	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HECICMKH_01137	1.18e-100	-	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HECICMKH_01138	3.3e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HECICMKH_01139	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HECICMKH_01140	1.64e-89	-	-	-	S	-	-	-	NUDIX domain
HECICMKH_01141	0.0	-	-	-	S	-	-	-	membrane
HECICMKH_01142	1.22e-217	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HECICMKH_01143	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HECICMKH_01144	5.12e-285	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HECICMKH_01145	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HECICMKH_01146	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HECICMKH_01147	3.39e-138	-	-	-	-	-	-	-	-
HECICMKH_01148	2.71e-150	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HECICMKH_01149	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_01150	5.19e-309	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HECICMKH_01151	0.0	-	-	-	-	-	-	-	-
HECICMKH_01152	4.75e-80	-	-	-	-	-	-	-	-
HECICMKH_01153	3.36e-248	-	-	-	S	-	-	-	Fn3-like domain
HECICMKH_01154	6.93e-139	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HECICMKH_01155	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HECICMKH_01156	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HECICMKH_01157	6.76e-73	-	-	-	-	-	-	-	-
HECICMKH_01158	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HECICMKH_01159	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_01160	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HECICMKH_01161	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HECICMKH_01162	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HECICMKH_01163	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HECICMKH_01164	1.69e-50	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HECICMKH_01165	1.91e-120	-	-	-	S	-	-	-	T5orf172
HECICMKH_01170	5.57e-16	-	-	-	-	-	-	-	-
HECICMKH_01171	2.67e-119	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
HECICMKH_01179	2.06e-09	-	-	-	-	-	-	-	-
HECICMKH_01181	8.68e-118	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HECICMKH_01182	2.4e-152	-	-	-	S	-	-	-	AAA domain
HECICMKH_01183	3.27e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HECICMKH_01184	6.62e-164	-	-	-	S	-	-	-	Putative HNHc nuclease
HECICMKH_01185	2.37e-97	-	-	-	L	-	-	-	DnaD domain protein
HECICMKH_01186	3.86e-167	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HECICMKH_01188	1.18e-58	-	-	-	-	-	-	-	-
HECICMKH_01190	5.24e-13	-	-	-	-	-	-	-	-
HECICMKH_01192	5.63e-12	-	-	-	S	-	-	-	YopX protein
HECICMKH_01194	1.06e-25	-	-	-	-	-	-	-	-
HECICMKH_01195	2.4e-47	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HECICMKH_01197	3.94e-17	-	-	-	-	-	-	-	-
HECICMKH_01200	1.41e-78	-	-	-	V	-	-	-	HNH nucleases
HECICMKH_01201	5.05e-51	-	-	-	L	-	-	-	Phage terminase, small subunit
HECICMKH_01202	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HECICMKH_01204	2.98e-181	-	-	-	S	-	-	-	Phage portal protein
HECICMKH_01205	9.98e-102	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HECICMKH_01206	1.64e-148	-	-	-	S	-	-	-	Phage capsid family
HECICMKH_01207	4.11e-31	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HECICMKH_01208	1.56e-17	-	-	-	S	-	-	-	Phage head-tail joining protein
HECICMKH_01209	6.11e-35	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HECICMKH_01210	2.17e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
HECICMKH_01211	2.81e-94	-	-	-	S	-	-	-	Phage tail tube protein
HECICMKH_01212	1.5e-18	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HECICMKH_01214	1.06e-254	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HECICMKH_01215	7.14e-287	-	-	-	S	-	-	-	Phage tail protein
HECICMKH_01216	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HECICMKH_01220	4.46e-74	-	-	-	-	-	-	-	-
HECICMKH_01221	2.04e-227	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HECICMKH_01222	3.19e-50	-	-	-	S	-	-	-	Haemolysin XhlA
HECICMKH_01225	2.35e-145	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HECICMKH_01226	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HECICMKH_01227	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HECICMKH_01228	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HECICMKH_01229	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HECICMKH_01230	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HECICMKH_01231	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HECICMKH_01232	8.63e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HECICMKH_01233	1.57e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HECICMKH_01234	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HECICMKH_01235	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HECICMKH_01236	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HECICMKH_01237	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HECICMKH_01238	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HECICMKH_01239	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HECICMKH_01240	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HECICMKH_01241	3.88e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HECICMKH_01242	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HECICMKH_01243	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HECICMKH_01244	6.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HECICMKH_01245	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HECICMKH_01246	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HECICMKH_01247	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HECICMKH_01248	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HECICMKH_01249	2.76e-74	-	-	-	-	-	-	-	-
HECICMKH_01250	8.2e-306	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HECICMKH_01251	7.09e-252	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HECICMKH_01252	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HECICMKH_01253	9.75e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HECICMKH_01254	9.51e-317	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HECICMKH_01255	1.81e-113	-	-	-	-	-	-	-	-
HECICMKH_01256	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HECICMKH_01257	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HECICMKH_01258	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HECICMKH_01259	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HECICMKH_01260	6.98e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HECICMKH_01261	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HECICMKH_01262	6.65e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
HECICMKH_01263	3.55e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HECICMKH_01264	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HECICMKH_01265	1.3e-125	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HECICMKH_01266	8.93e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HECICMKH_01267	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HECICMKH_01268	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HECICMKH_01269	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HECICMKH_01270	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HECICMKH_01271	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HECICMKH_01272	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HECICMKH_01273	2.36e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HECICMKH_01274	1.21e-129	-	-	-	S	-	-	-	SdpI/YhfL protein family
HECICMKH_01275	1.15e-207	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HECICMKH_01276	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HECICMKH_01277	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HECICMKH_01278	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HECICMKH_01279	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HECICMKH_01280	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HECICMKH_01281	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HECICMKH_01282	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HECICMKH_01283	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HECICMKH_01284	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HECICMKH_01285	9.72e-146	-	-	-	S	-	-	-	membrane
HECICMKH_01286	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
HECICMKH_01287	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HECICMKH_01288	0.0	-	-	-	S	-	-	-	membrane
HECICMKH_01289	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HECICMKH_01290	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HECICMKH_01291	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HECICMKH_01292	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HECICMKH_01293	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HECICMKH_01294	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HECICMKH_01295	4.65e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HECICMKH_01296	6.68e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HECICMKH_01297	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HECICMKH_01298	1.83e-177	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HECICMKH_01299	1.33e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HECICMKH_01300	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HECICMKH_01301	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HECICMKH_01302	1.77e-205	-	-	-	-	-	-	-	-
HECICMKH_01303	1.34e-232	-	-	-	-	-	-	-	-
HECICMKH_01304	2.05e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
HECICMKH_01305	1.87e-74	-	-	-	-	-	-	-	-
HECICMKH_01306	2.97e-41	-	-	-	-	-	-	-	-
HECICMKH_01309	9.81e-27	-	-	-	-	-	-	-	-
HECICMKH_01310	2.72e-123	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_01311	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HECICMKH_01312	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HECICMKH_01313	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HECICMKH_01314	6.04e-249	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HECICMKH_01315	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HECICMKH_01316	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HECICMKH_01317	9.43e-90	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HECICMKH_01318	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HECICMKH_01319	3.99e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HECICMKH_01320	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HECICMKH_01321	5.49e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HECICMKH_01322	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HECICMKH_01323	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HECICMKH_01324	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HECICMKH_01325	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_01326	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HECICMKH_01327	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HECICMKH_01328	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECICMKH_01329	2.38e-72	-	-	-	-	-	-	-	-
HECICMKH_01330	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HECICMKH_01331	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HECICMKH_01332	5.04e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HECICMKH_01333	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HECICMKH_01334	1.49e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HECICMKH_01335	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HECICMKH_01336	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HECICMKH_01337	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HECICMKH_01338	9.49e-207	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HECICMKH_01339	2.22e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HECICMKH_01340	2.61e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HECICMKH_01341	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HECICMKH_01342	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HECICMKH_01343	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HECICMKH_01344	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HECICMKH_01345	1.79e-243	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HECICMKH_01346	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HECICMKH_01347	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HECICMKH_01348	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HECICMKH_01349	8.55e-295	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HECICMKH_01350	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HECICMKH_01351	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HECICMKH_01352	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HECICMKH_01353	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HECICMKH_01354	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HECICMKH_01355	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HECICMKH_01356	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HECICMKH_01357	1.03e-66	-	-	-	-	-	-	-	-
HECICMKH_01358	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HECICMKH_01359	1.1e-112	-	-	-	-	-	-	-	-
HECICMKH_01360	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HECICMKH_01361	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HECICMKH_01362	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HECICMKH_01363	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HECICMKH_01364	1.42e-224	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HECICMKH_01365	6.06e-159	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HECICMKH_01366	1.51e-140	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HECICMKH_01367	1.79e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HECICMKH_01368	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HECICMKH_01369	1.45e-126	entB	-	-	Q	-	-	-	Isochorismatase family
HECICMKH_01370	3.53e-227	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HECICMKH_01371	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HECICMKH_01372	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HECICMKH_01373	1.38e-273	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HECICMKH_01374	1.56e-251	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HECICMKH_01375	2.12e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HECICMKH_01376	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HECICMKH_01377	8.02e-230	yneE	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_01378	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HECICMKH_01379	1.97e-230	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HECICMKH_01380	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HECICMKH_01381	2.97e-216	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HECICMKH_01382	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HECICMKH_01383	3.11e-289	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HECICMKH_01384	5.25e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HECICMKH_01385	7.23e-93	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HECICMKH_01386	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HECICMKH_01387	2.62e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HECICMKH_01388	1.96e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HECICMKH_01389	5.4e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HECICMKH_01390	1.01e-128	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HECICMKH_01391	3.64e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HECICMKH_01392	1.07e-206	-	-	-	K	-	-	-	LysR substrate binding domain
HECICMKH_01393	4.94e-114	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HECICMKH_01394	2.66e-247	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HECICMKH_01395	2.46e-120	-	-	-	K	-	-	-	transcriptional regulator
HECICMKH_01396	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HECICMKH_01397	6.56e-193	-	-	-	O	-	-	-	Band 7 protein
HECICMKH_01398	8.14e-47	-	-	-	L	-	-	-	Pfam:Integrase_AP2
HECICMKH_01402	1.19e-13	-	-	-	-	-	-	-	-
HECICMKH_01404	1.43e-69	-	-	-	-	-	-	-	-
HECICMKH_01405	1.42e-39	-	-	-	-	-	-	-	-
HECICMKH_01406	1.69e-276	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HECICMKH_01407	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HECICMKH_01408	3.16e-64	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HECICMKH_01409	2.05e-55	-	-	-	-	-	-	-	-
HECICMKH_01410	4.98e-107	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HECICMKH_01411	3.05e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HECICMKH_01412	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HECICMKH_01413	1.03e-210	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HECICMKH_01414	1.51e-48	-	-	-	-	-	-	-	-
HECICMKH_01415	5.79e-21	-	-	-	-	-	-	-	-
HECICMKH_01416	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HECICMKH_01417	4e-40	-	-	-	S	-	-	-	CsbD-like
HECICMKH_01418	1.06e-53	-	-	-	-	-	-	-	-
HECICMKH_01419	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HECICMKH_01420	4.87e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HECICMKH_01421	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HECICMKH_01422	1.04e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HECICMKH_01423	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HECICMKH_01424	1.52e-67	-	-	-	-	-	-	-	-
HECICMKH_01425	2.12e-57	-	-	-	-	-	-	-	-
HECICMKH_01426	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HECICMKH_01427	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HECICMKH_01428	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HECICMKH_01429	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HECICMKH_01430	2.06e-158	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HECICMKH_01431	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HECICMKH_01432	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HECICMKH_01433	9.23e-245	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HECICMKH_01434	1.01e-249	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HECICMKH_01435	1.77e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HECICMKH_01436	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HECICMKH_01437	4.23e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HECICMKH_01438	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HECICMKH_01439	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HECICMKH_01440	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HECICMKH_01441	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HECICMKH_01442	1.13e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HECICMKH_01444	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HECICMKH_01445	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HECICMKH_01446	1.3e-202	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HECICMKH_01447	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
HECICMKH_01448	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECICMKH_01449	1.34e-232	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HECICMKH_01450	2.8e-229	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HECICMKH_01451	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HECICMKH_01452	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HECICMKH_01453	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HECICMKH_01454	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HECICMKH_01456	4.11e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HECICMKH_01458	1.7e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HECICMKH_01459	2.26e-95	-	-	-	S	-	-	-	SnoaL-like domain
HECICMKH_01460	3.2e-254	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HECICMKH_01461	2.85e-266	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HECICMKH_01462	3.9e-100	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HECICMKH_01463	2.13e-312	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HECICMKH_01464	1.44e-234	-	-	-	V	-	-	-	LD-carboxypeptidase
HECICMKH_01465	1.99e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HECICMKH_01466	3.99e-158	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECICMKH_01467	1.37e-248	-	-	-	-	-	-	-	-
HECICMKH_01468	1.5e-186	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HECICMKH_01469	1.47e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HECICMKH_01470	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HECICMKH_01471	5.04e-82	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HECICMKH_01472	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HECICMKH_01473	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HECICMKH_01474	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HECICMKH_01475	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HECICMKH_01476	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HECICMKH_01477	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HECICMKH_01478	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HECICMKH_01479	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HECICMKH_01480	1.9e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HECICMKH_01483	1.11e-167	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HECICMKH_01484	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HECICMKH_01485	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HECICMKH_01486	1.87e-117	-	-	-	F	-	-	-	NUDIX domain
HECICMKH_01487	5.08e-207	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_01488	1.54e-169	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HECICMKH_01489	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HECICMKH_01490	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_01491	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HECICMKH_01492	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HECICMKH_01493	2.9e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HECICMKH_01494	3.72e-38	-	-	-	-	-	-	-	-
HECICMKH_01495	5.59e-64	-	-	-	-	-	-	-	-
HECICMKH_01496	3.84e-188	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HECICMKH_01497	3.87e-264	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HECICMKH_01499	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HECICMKH_01500	2.98e-166	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HECICMKH_01501	2.59e-177	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HECICMKH_01502	1.01e-310	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HECICMKH_01503	7.1e-252	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HECICMKH_01504	1.3e-174	-	-	-	-	-	-	-	-
HECICMKH_01505	7.79e-78	-	-	-	-	-	-	-	-
HECICMKH_01506	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HECICMKH_01507	6.75e-290	-	-	-	-	-	-	-	-
HECICMKH_01508	7.15e-165	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HECICMKH_01509	2.44e-242	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HECICMKH_01510	3.21e-247	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HECICMKH_01511	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HECICMKH_01512	6.39e-119	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HECICMKH_01513	1.6e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HECICMKH_01514	3.22e-304	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HECICMKH_01515	1.98e-66	-	-	-	-	-	-	-	-
HECICMKH_01516	4.49e-315	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HECICMKH_01517	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HECICMKH_01518	5.95e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HECICMKH_01519	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HECICMKH_01520	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HECICMKH_01521	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HECICMKH_01522	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HECICMKH_01523	1.56e-227	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_01524	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HECICMKH_01525	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HECICMKH_01526	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HECICMKH_01527	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HECICMKH_01528	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HECICMKH_01529	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HECICMKH_01530	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HECICMKH_01531	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HECICMKH_01532	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HECICMKH_01533	1.1e-200	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HECICMKH_01534	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HECICMKH_01535	1.85e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HECICMKH_01537	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
HECICMKH_01538	4.08e-218	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HECICMKH_01539	1.23e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HECICMKH_01540	2.48e-252	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HECICMKH_01541	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HECICMKH_01542	1.68e-154	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HECICMKH_01543	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HECICMKH_01544	1.26e-79	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HECICMKH_01545	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HECICMKH_01546	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HECICMKH_01547	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HECICMKH_01548	2.4e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HECICMKH_01549	2.88e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HECICMKH_01550	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HECICMKH_01551	6.7e-241	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HECICMKH_01552	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HECICMKH_01553	6.46e-109	-	-	-	-	-	-	-	-
HECICMKH_01554	8.95e-292	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HECICMKH_01555	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HECICMKH_01556	4.33e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HECICMKH_01557	5.96e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HECICMKH_01558	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HECICMKH_01559	2.06e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HECICMKH_01560	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HECICMKH_01561	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HECICMKH_01562	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HECICMKH_01563	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HECICMKH_01564	1.13e-250	-	-	-	S	-	-	-	Helix-turn-helix domain
HECICMKH_01565	3.57e-123	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HECICMKH_01566	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HECICMKH_01567	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HECICMKH_01568	1.18e-174	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HECICMKH_01569	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HECICMKH_01570	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HECICMKH_01571	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HECICMKH_01572	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HECICMKH_01573	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HECICMKH_01574	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HECICMKH_01575	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HECICMKH_01576	2.02e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HECICMKH_01577	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HECICMKH_01578	9.08e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HECICMKH_01579	3.25e-251	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HECICMKH_01580	8.34e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HECICMKH_01581	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
HECICMKH_01582	8.81e-166	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HECICMKH_01583	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HECICMKH_01584	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HECICMKH_01585	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HECICMKH_01586	2.27e-82	-	-	-	P	-	-	-	Rhodanese Homology Domain
HECICMKH_01587	7.43e-119	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HECICMKH_01588	1.93e-266	-	-	-	-	-	-	-	-
HECICMKH_01589	5.21e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HECICMKH_01590	1.51e-232	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HECICMKH_01591	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HECICMKH_01592	2.2e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HECICMKH_01593	3.61e-304	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HECICMKH_01594	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_01595	7.87e-266	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HECICMKH_01596	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HECICMKH_01597	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HECICMKH_01598	1.25e-140	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HECICMKH_01599	3.1e-92	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HECICMKH_01600	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HECICMKH_01601	4.88e-147	-	-	-	GM	-	-	-	epimerase
HECICMKH_01602	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HECICMKH_01603	5.04e-155	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HECICMKH_01604	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HECICMKH_01605	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HECICMKH_01606	3.74e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
HECICMKH_01607	5.89e-145	-	-	-	GM	-	-	-	NmrA-like family
HECICMKH_01608	9.69e-99	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HECICMKH_01609	3.86e-205	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_01610	1.04e-218	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HECICMKH_01611	1.58e-21	-	-	-	S	-	-	-	Alpha beta hydrolase
HECICMKH_01612	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HECICMKH_01613	3.71e-133	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HECICMKH_01614	7.78e-261	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HECICMKH_01615	7.05e-172	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HECICMKH_01616	4.87e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HECICMKH_01618	9.07e-107	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HECICMKH_01619	9.55e-95	-	-	-	K	-	-	-	MarR family
HECICMKH_01620	1.49e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HECICMKH_01621	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_01622	2.11e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HECICMKH_01623	5.21e-254	-	-	-	-	-	-	-	-
HECICMKH_01624	2.59e-256	-	-	-	-	-	-	-	-
HECICMKH_01625	2.45e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_01626	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HECICMKH_01627	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HECICMKH_01628	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HECICMKH_01629	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HECICMKH_01630	1.01e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HECICMKH_01631	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HECICMKH_01632	4.58e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HECICMKH_01633	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HECICMKH_01634	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HECICMKH_01635	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HECICMKH_01636	1.53e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HECICMKH_01637	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HECICMKH_01638	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HECICMKH_01639	3.65e-166	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HECICMKH_01640	7.36e-220	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HECICMKH_01641	5.49e-286	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HECICMKH_01642	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HECICMKH_01643	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HECICMKH_01644	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HECICMKH_01645	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HECICMKH_01646	2.83e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HECICMKH_01647	3.23e-214	-	-	-	G	-	-	-	Fructosamine kinase
HECICMKH_01648	5.97e-151	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HECICMKH_01649	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HECICMKH_01650	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HECICMKH_01651	2.56e-76	-	-	-	-	-	-	-	-
HECICMKH_01652	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HECICMKH_01653	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HECICMKH_01654	1.11e-147	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HECICMKH_01655	4.78e-65	-	-	-	-	-	-	-	-
HECICMKH_01656	1.73e-67	-	-	-	-	-	-	-	-
HECICMKH_01657	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HECICMKH_01658	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HECICMKH_01659	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HECICMKH_01660	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HECICMKH_01661	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HECICMKH_01662	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HECICMKH_01663	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HECICMKH_01664	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HECICMKH_01665	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HECICMKH_01666	4.94e-115	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HECICMKH_01667	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HECICMKH_01668	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HECICMKH_01669	7.56e-242	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HECICMKH_01670	6.29e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HECICMKH_01671	1.45e-114	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HECICMKH_01672	8.88e-248	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HECICMKH_01673	8.18e-303	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HECICMKH_01674	1.63e-121	-	-	-	-	-	-	-	-
HECICMKH_01675	9.01e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HECICMKH_01676	0.0	-	-	-	G	-	-	-	Major Facilitator
HECICMKH_01677	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HECICMKH_01678	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HECICMKH_01679	5.46e-62	ylxQ	-	-	J	-	-	-	ribosomal protein
HECICMKH_01680	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HECICMKH_01681	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HECICMKH_01682	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HECICMKH_01683	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HECICMKH_01684	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HECICMKH_01685	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HECICMKH_01686	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HECICMKH_01687	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HECICMKH_01688	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HECICMKH_01689	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HECICMKH_01690	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HECICMKH_01691	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HECICMKH_01692	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HECICMKH_01693	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HECICMKH_01694	1.02e-66	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HECICMKH_01695	1.14e-175	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HECICMKH_01696	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HECICMKH_01697	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HECICMKH_01698	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HECICMKH_01699	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HECICMKH_01700	7.8e-123	-	-	-	-	-	-	-	-
HECICMKH_01701	1.56e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HECICMKH_01702	1.01e-100	-	-	-	-	-	-	-	-
HECICMKH_01703	3.81e-87	-	-	-	-	-	-	-	-
HECICMKH_01704	2.3e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HECICMKH_01705	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HECICMKH_01706	1.89e-282	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HECICMKH_01707	1.1e-183	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECICMKH_01708	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECICMKH_01709	2.38e-294	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HECICMKH_01711	5.03e-43	-	-	-	-	-	-	-	-
HECICMKH_01712	1.62e-155	-	-	-	Q	-	-	-	Methyltransferase
HECICMKH_01713	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HECICMKH_01714	6.75e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HECICMKH_01715	4.57e-135	-	-	-	K	-	-	-	Helix-turn-helix domain
HECICMKH_01716	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HECICMKH_01717	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HECICMKH_01718	7.49e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HECICMKH_01719	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HECICMKH_01720	3.97e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HECICMKH_01721	6.62e-62	-	-	-	-	-	-	-	-
HECICMKH_01722	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HECICMKH_01723	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HECICMKH_01724	1.73e-217	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HECICMKH_01725	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HECICMKH_01726	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HECICMKH_01727	0.0	cps4J	-	-	S	-	-	-	MatE
HECICMKH_01728	2.39e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HECICMKH_01729	2.28e-288	-	-	-	-	-	-	-	-
HECICMKH_01730	1.9e-235	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HECICMKH_01731	1.4e-259	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HECICMKH_01732	2.33e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HECICMKH_01733	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HECICMKH_01734	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HECICMKH_01735	4.08e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HECICMKH_01736	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
HECICMKH_01737	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HECICMKH_01738	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HECICMKH_01739	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HECICMKH_01740	1.47e-30	-	-	-	-	-	-	-	-
HECICMKH_01741	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HECICMKH_01742	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HECICMKH_01743	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HECICMKH_01744	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HECICMKH_01745	6.48e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HECICMKH_01746	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HECICMKH_01747	4.84e-203	-	-	-	S	-	-	-	Tetratricopeptide repeat
HECICMKH_01748	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HECICMKH_01749	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HECICMKH_01750	7.41e-260	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HECICMKH_01751	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HECICMKH_01752	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HECICMKH_01753	5.09e-241	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HECICMKH_01754	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HECICMKH_01755	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HECICMKH_01756	2.56e-162	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HECICMKH_01757	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HECICMKH_01758	2.99e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HECICMKH_01759	4.98e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HECICMKH_01760	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HECICMKH_01761	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HECICMKH_01762	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HECICMKH_01763	1e-191	-	-	-	-	-	-	-	-
HECICMKH_01764	5.96e-160	-	-	-	-	-	-	-	-
HECICMKH_01765	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HECICMKH_01766	9.51e-135	-	-	-	-	-	-	-	-
HECICMKH_01767	9.43e-259	-	-	-	-	-	-	-	-
HECICMKH_01768	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HECICMKH_01769	1.23e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HECICMKH_01770	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HECICMKH_01771	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HECICMKH_01772	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HECICMKH_01773	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HECICMKH_01774	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HECICMKH_01775	2.86e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HECICMKH_01776	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HECICMKH_01777	6.45e-111	-	-	-	-	-	-	-	-
HECICMKH_01778	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HECICMKH_01779	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HECICMKH_01780	5.96e-241	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HECICMKH_01781	2.16e-39	-	-	-	-	-	-	-	-
HECICMKH_01782	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HECICMKH_01783	1.53e-219	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HECICMKH_01784	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HECICMKH_01785	1.68e-154	-	-	-	S	-	-	-	repeat protein
HECICMKH_01786	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HECICMKH_01787	0.0	-	-	-	N	-	-	-	domain, Protein
HECICMKH_01788	1e-247	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HECICMKH_01789	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HECICMKH_01790	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HECICMKH_01791	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HECICMKH_01792	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HECICMKH_01793	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HECICMKH_01794	3.69e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HECICMKH_01795	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HECICMKH_01796	7.74e-47	-	-	-	-	-	-	-	-
HECICMKH_01797	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HECICMKH_01798	9.93e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HECICMKH_01799	2.05e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HECICMKH_01800	2.57e-47	-	-	-	K	-	-	-	LytTr DNA-binding domain
HECICMKH_01801	1.47e-100	-	-	-	U	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HECICMKH_01802	3.64e-101	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HECICMKH_01803	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HECICMKH_01804	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HECICMKH_01805	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HECICMKH_01806	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HECICMKH_01807	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HECICMKH_01808	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HECICMKH_01809	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HECICMKH_01810	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HECICMKH_01811	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HECICMKH_01812	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HECICMKH_01813	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HECICMKH_01814	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HECICMKH_01815	1.16e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HECICMKH_01816	2.12e-225	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HECICMKH_01817	7.24e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HECICMKH_01818	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HECICMKH_01819	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HECICMKH_01820	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HECICMKH_01821	1.95e-121	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HECICMKH_01822	1.44e-146	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HECICMKH_01823	2.17e-302	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HECICMKH_01825	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HECICMKH_01826	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HECICMKH_01827	2.24e-262	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HECICMKH_01828	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HECICMKH_01829	5.57e-247	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HECICMKH_01830	2.51e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HECICMKH_01831	1.09e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HECICMKH_01832	5.27e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HECICMKH_01833	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HECICMKH_01834	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HECICMKH_01835	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HECICMKH_01836	2.34e-266	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HECICMKH_01837	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HECICMKH_01838	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HECICMKH_01839	3.28e-177	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HECICMKH_01840	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HECICMKH_01841	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HECICMKH_01863	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HECICMKH_01864	1.11e-84	-	-	-	-	-	-	-	-
HECICMKH_01865	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HECICMKH_01866	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HECICMKH_01867	7.18e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HECICMKH_01868	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HECICMKH_01869	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HECICMKH_01870	6.53e-115	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HECICMKH_01871	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HECICMKH_01872	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HECICMKH_01873	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HECICMKH_01874	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HECICMKH_01875	1.56e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HECICMKH_01877	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HECICMKH_01878	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HECICMKH_01879	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HECICMKH_01880	1.14e-71	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HECICMKH_01881	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HECICMKH_01882	1.55e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HECICMKH_01883	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HECICMKH_01884	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HECICMKH_01885	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HECICMKH_01886	7.88e-211	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HECICMKH_01887	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HECICMKH_01888	1.55e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HECICMKH_01889	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HECICMKH_01890	1.6e-96	-	-	-	-	-	-	-	-
HECICMKH_01891	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HECICMKH_01892	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HECICMKH_01893	7.85e-288	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HECICMKH_01894	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HECICMKH_01895	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HECICMKH_01896	2.62e-121	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HECICMKH_01897	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HECICMKH_01898	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HECICMKH_01899	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HECICMKH_01900	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HECICMKH_01901	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HECICMKH_01902	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HECICMKH_01903	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HECICMKH_01904	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HECICMKH_01905	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HECICMKH_01906	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HECICMKH_01907	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HECICMKH_01908	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HECICMKH_01909	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HECICMKH_01910	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HECICMKH_01911	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HECICMKH_01912	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HECICMKH_01913	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HECICMKH_01914	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HECICMKH_01915	2.07e-118	-	-	-	-	-	-	-	-
HECICMKH_01916	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HECICMKH_01917	1.35e-93	-	-	-	-	-	-	-	-
HECICMKH_01918	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HECICMKH_01919	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HECICMKH_01920	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HECICMKH_01921	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HECICMKH_01922	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HECICMKH_01923	4.47e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HECICMKH_01924	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HECICMKH_01925	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HECICMKH_01926	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HECICMKH_01927	8.72e-297	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HECICMKH_01928	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HECICMKH_01929	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HECICMKH_01930	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HECICMKH_01931	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HECICMKH_01932	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HECICMKH_01933	5.41e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HECICMKH_01934	1.11e-113	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HECICMKH_01935	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HECICMKH_01936	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HECICMKH_01937	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HECICMKH_01938	9.36e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HECICMKH_01939	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HECICMKH_01940	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HECICMKH_01941	4.5e-299	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HECICMKH_01942	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HECICMKH_01943	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HECICMKH_01944	2.22e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HECICMKH_01945	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HECICMKH_01946	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HECICMKH_01947	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HECICMKH_01948	1.15e-144	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HECICMKH_01949	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HECICMKH_01950	1.57e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HECICMKH_01951	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HECICMKH_01952	7.24e-291	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HECICMKH_01953	3.43e-55	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HECICMKH_01954	5.82e-139	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
HECICMKH_01955	4.54e-132	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HECICMKH_01956	3.79e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HECICMKH_01957	1.31e-119	-	-	-	K	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
HECICMKH_01958	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HECICMKH_01959	2.96e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HECICMKH_01960	1.34e-52	-	-	-	-	-	-	-	-
HECICMKH_01961	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HECICMKH_01962	1.91e-259	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HECICMKH_01963	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HECICMKH_01964	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HECICMKH_01965	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HECICMKH_01966	1.78e-240	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HECICMKH_01967	1.88e-226	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HECICMKH_01968	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HECICMKH_01969	1.23e-190	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HECICMKH_01970	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HECICMKH_01971	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HECICMKH_01972	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HECICMKH_01973	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HECICMKH_01974	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HECICMKH_01975	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HECICMKH_01976	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HECICMKH_01977	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HECICMKH_01978	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HECICMKH_01979	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HECICMKH_01980	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HECICMKH_01981	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HECICMKH_01982	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HECICMKH_01983	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HECICMKH_01984	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HECICMKH_01985	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HECICMKH_01986	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HECICMKH_01987	1.01e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HECICMKH_01988	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HECICMKH_01989	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HECICMKH_01990	4.39e-244	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HECICMKH_01991	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HECICMKH_01992	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HECICMKH_01993	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HECICMKH_01994	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HECICMKH_01995	1.83e-175	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HECICMKH_01996	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HECICMKH_01997	9.24e-246	ampC	-	-	V	-	-	-	Beta-lactamase
HECICMKH_01998	8.57e-41	-	-	-	-	-	-	-	-
HECICMKH_01999	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HECICMKH_02000	1.33e-77	-	-	-	-	-	-	-	-
HECICMKH_02001	5.37e-182	-	-	-	-	-	-	-	-
HECICMKH_02002	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HECICMKH_02003	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HECICMKH_02004	5.63e-89	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HECICMKH_02005	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HECICMKH_02008	7.05e-50	-	-	-	S	-	-	-	Bacteriophage holin
HECICMKH_02009	5.1e-58	-	-	-	-	-	-	-	-
HECICMKH_02010	6.44e-264	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HECICMKH_02012	4.36e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1617)
HECICMKH_02013	0.0	-	-	-	LM	-	-	-	DNA recombination
HECICMKH_02014	2.29e-81	-	-	-	-	-	-	-	-
HECICMKH_02015	0.0	-	-	-	D	-	-	-	domain protein
HECICMKH_02016	3.76e-32	-	-	-	-	-	-	-	-
HECICMKH_02017	1.42e-83	-	-	-	-	-	-	-	-
HECICMKH_02018	7.42e-102	-	-	-	S	-	-	-	Phage tail tube protein, TTP
HECICMKH_02019	3.49e-72	-	-	-	-	-	-	-	-
HECICMKH_02020	5.34e-115	-	-	-	-	-	-	-	-
HECICMKH_02021	9.63e-68	-	-	-	-	-	-	-	-
HECICMKH_02022	1.68e-67	-	-	-	-	-	-	-	-
HECICMKH_02024	2.08e-222	-	-	-	S	-	-	-	Phage major capsid protein E
HECICMKH_02025	5.72e-64	-	-	-	-	-	-	-	-
HECICMKH_02028	6.16e-41	-	-	-	-	-	-	-	-
HECICMKH_02029	0.0	-	-	-	S	-	-	-	Phage Mu protein F like protein
HECICMKH_02030	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HECICMKH_02031	2.99e-272	-	-	-	S	-	-	-	Terminase-like family
HECICMKH_02032	9.11e-111	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HECICMKH_02033	7.08e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HECICMKH_02037	1.57e-106	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
HECICMKH_02039	3.06e-18	-	-	-	-	-	-	-	-
HECICMKH_02041	5.95e-06	-	-	-	-	-	-	-	-
HECICMKH_02042	4.69e-86	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HECICMKH_02043	2.35e-83	-	-	-	-	-	-	-	-
HECICMKH_02044	8.64e-63	-	-	-	-	-	-	-	-
HECICMKH_02045	3.18e-207	-	-	-	L	-	-	-	DnaD domain protein
HECICMKH_02046	7.88e-78	-	-	-	-	-	-	-	-
HECICMKH_02047	2.8e-70	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HECICMKH_02051	4e-106	-	-	-	-	-	-	-	-
HECICMKH_02052	7.71e-71	-	-	-	-	-	-	-	-
HECICMKH_02055	1.13e-36	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HECICMKH_02056	8.29e-51	-	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
HECICMKH_02058	6.06e-08	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HECICMKH_02059	1.38e-82	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HECICMKH_02060	2.62e-95	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HECICMKH_02061	1.08e-105	-	-	-	-	-	-	-	-
HECICMKH_02063	2.24e-19	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HECICMKH_02066	4.71e-47	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HECICMKH_02068	9.51e-48	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HECICMKH_02071	2.46e-119	-	-	-	S	-	-	-	AAA domain
HECICMKH_02074	5.42e-278	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HECICMKH_02076	1.98e-40	-	-	-	-	-	-	-	-
HECICMKH_02078	1.28e-51	-	-	-	-	-	-	-	-
HECICMKH_02079	1.87e-57	-	-	-	-	-	-	-	-
HECICMKH_02080	1.27e-109	-	-	-	K	-	-	-	MarR family
HECICMKH_02081	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HECICMKH_02082	0.0	inlJ	-	-	M	-	-	-	MucBP domain
HECICMKH_02083	6.58e-24	-	-	-	-	-	-	-	-
HECICMKH_02084	3.26e-24	-	-	-	-	-	-	-	-
HECICMKH_02085	1.56e-22	-	-	-	-	-	-	-	-
HECICMKH_02086	1.07e-26	-	-	-	-	-	-	-	-
HECICMKH_02087	9.35e-24	-	-	-	-	-	-	-	-
HECICMKH_02088	9.35e-24	-	-	-	-	-	-	-	-
HECICMKH_02089	9.35e-24	-	-	-	-	-	-	-	-
HECICMKH_02090	2.16e-26	-	-	-	-	-	-	-	-
HECICMKH_02091	7.71e-23	-	-	-	-	-	-	-	-
HECICMKH_02092	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HECICMKH_02093	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HECICMKH_02094	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_02095	2.1e-33	-	-	-	-	-	-	-	-
HECICMKH_02096	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HECICMKH_02097	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HECICMKH_02098	2.13e-276	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HECICMKH_02099	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HECICMKH_02100	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HECICMKH_02101	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HECICMKH_02102	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HECICMKH_02103	1.26e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HECICMKH_02107	1.84e-16	-	-	-	-	-	-	-	-
HECICMKH_02108	4.36e-50	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HECICMKH_02109	1.51e-53	-	-	-	L	-	-	-	HTH-like domain
HECICMKH_02110	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HECICMKH_02111	5.34e-64	-	-	-	-	-	-	-	-
HECICMKH_02112	3.95e-273	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HECICMKH_02113	1.9e-176	-	-	-	F	-	-	-	NUDIX domain
HECICMKH_02114	2.68e-32	-	-	-	-	-	-	-	-
HECICMKH_02116	1.58e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HECICMKH_02117	4.27e-223	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HECICMKH_02118	4.17e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HECICMKH_02119	2.29e-48	-	-	-	-	-	-	-	-
HECICMKH_02120	1.11e-45	-	-	-	-	-	-	-	-
HECICMKH_02121	3.14e-275	-	-	-	T	-	-	-	diguanylate cyclase
HECICMKH_02122	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HECICMKH_02123	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HECICMKH_02124	5.76e-107	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HECICMKH_02125	3.1e-15	-	-	-	-	-	-	-	-
HECICMKH_02126	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HECICMKH_02127	1.25e-240	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HECICMKH_02128	2.84e-208	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HECICMKH_02129	8.69e-295	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HECICMKH_02130	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HECICMKH_02131	3.77e-214	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HECICMKH_02132	2.79e-226	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HECICMKH_02133	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HECICMKH_02134	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_02135	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HECICMKH_02136	1.92e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HECICMKH_02137	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HECICMKH_02138	1.48e-14	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
HECICMKH_02139	1.33e-08	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HECICMKH_02140	1.28e-256	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HECICMKH_02141	4.37e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HECICMKH_02142	2.49e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HECICMKH_02143	2.11e-171	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HECICMKH_02144	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HECICMKH_02145	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HECICMKH_02146	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HECICMKH_02147	1.57e-298	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HECICMKH_02148	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HECICMKH_02149	1.39e-276	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HECICMKH_02150	1.3e-207	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HECICMKH_02151	5.28e-283	ysaA	-	-	V	-	-	-	RDD family
HECICMKH_02152	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HECICMKH_02153	1.71e-67	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HECICMKH_02154	2.54e-17	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HECICMKH_02155	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HECICMKH_02156	2.83e-238	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HECICMKH_02157	1.45e-46	-	-	-	-	-	-	-	-
HECICMKH_02158	1.26e-143	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HECICMKH_02159	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HECICMKH_02160	0.0	-	-	-	M	-	-	-	domain protein
HECICMKH_02161	3e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HECICMKH_02162	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HECICMKH_02163	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HECICMKH_02164	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HECICMKH_02165	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HECICMKH_02166	4.32e-247	-	-	-	S	-	-	-	domain, Protein
HECICMKH_02167	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HECICMKH_02168	2.57e-128	-	-	-	C	-	-	-	Nitroreductase family
HECICMKH_02169	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HECICMKH_02170	2.43e-209	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HECICMKH_02171	1.91e-198	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HECICMKH_02172	1.79e-92	-	-	-	GK	-	-	-	ROK family
HECICMKH_02173	1.13e-112	-	-	-	GK	-	-	-	ROK family
HECICMKH_02174	2.08e-199	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HECICMKH_02175	1.18e-172	rdrA	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HECICMKH_02176	0.0	pflD	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HECICMKH_02177	1.75e-227	-	-	-	K	-	-	-	sugar-binding domain protein
HECICMKH_02178	2.11e-159	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
HECICMKH_02179	2.13e-182	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HECICMKH_02180	2.89e-224	ccpB	-	-	K	-	-	-	lacI family
HECICMKH_02181	5.28e-203	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HECICMKH_02182	3.38e-225	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HECICMKH_02183	1.81e-252	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HECICMKH_02184	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HECICMKH_02185	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HECICMKH_02186	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HECICMKH_02187	2.66e-172	-	-	-	-	-	-	-	-
HECICMKH_02188	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HECICMKH_02189	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HECICMKH_02190	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HECICMKH_02191	3.25e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HECICMKH_02192	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HECICMKH_02193	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_02194	6.23e-209	-	-	-	-	-	-	-	-
HECICMKH_02195	1.23e-75	-	-	-	-	-	-	-	-
HECICMKH_02196	1.44e-65	-	-	-	-	-	-	-	-
HECICMKH_02197	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HECICMKH_02198	4.09e-89	-	-	-	-	-	-	-	-
HECICMKH_02199	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HECICMKH_02200	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HECICMKH_02201	6.69e-263	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HECICMKH_02202	3.89e-62	-	-	-	-	-	-	-	-
HECICMKH_02203	3.11e-76	-	-	-	-	-	-	-	-
HECICMKH_02204	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HECICMKH_02205	1.65e-97	-	-	-	-	-	-	-	-
HECICMKH_02206	4.15e-78	-	-	-	-	-	-	-	-
HECICMKH_02207	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HECICMKH_02208	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HECICMKH_02209	1.63e-95	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HECICMKH_02210	3.82e-188	agaD	-	-	G	ko:K02747,ko:K02796,ko:K10986	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HECICMKH_02211	5.2e-185	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HECICMKH_02212	1.49e-112	-	2.7.1.191	-	K	ko:K02745,ko:K02794,ko:K10984	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HECICMKH_02213	5.87e-166	-	-	-	K	ko:K03710	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HECICMKH_02214	2.51e-103	uspA3	-	-	T	-	-	-	universal stress protein
HECICMKH_02215	1.84e-205	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HECICMKH_02216	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HECICMKH_02217	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HECICMKH_02218	3.07e-284	-	-	-	M	-	-	-	Glycosyl transferases group 1
HECICMKH_02219	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HECICMKH_02220	3.74e-205	-	-	-	S	-	-	-	Putative esterase
HECICMKH_02221	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_02222	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HECICMKH_02223	1.74e-178	-	-	-	-	-	-	-	-
HECICMKH_02224	4.85e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HECICMKH_02225	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HECICMKH_02226	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HECICMKH_02227	5.4e-80	-	-	-	-	-	-	-	-
HECICMKH_02228	7.48e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HECICMKH_02229	2.97e-76	-	-	-	-	-	-	-	-
HECICMKH_02230	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HECICMKH_02231	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HECICMKH_02232	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HECICMKH_02233	1.17e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
HECICMKH_02234	4.71e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HECICMKH_02235	8.91e-220	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HECICMKH_02236	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HECICMKH_02237	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HECICMKH_02238	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HECICMKH_02239	4.14e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HECICMKH_02240	1.46e-131	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HECICMKH_02241	3.59e-26	-	-	-	-	-	-	-	-
HECICMKH_02242	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HECICMKH_02243	5.73e-208	mleR	-	-	K	-	-	-	LysR family
HECICMKH_02244	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HECICMKH_02245	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HECICMKH_02246	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HECICMKH_02247	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HECICMKH_02248	9.44e-219	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HECICMKH_02249	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HECICMKH_02250	1.09e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HECICMKH_02251	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HECICMKH_02252	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HECICMKH_02253	4.77e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HECICMKH_02254	2.38e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HECICMKH_02255	1.22e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HECICMKH_02256	1.01e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HECICMKH_02257	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HECICMKH_02258	4.41e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HECICMKH_02259	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HECICMKH_02260	4.71e-208	-	-	-	GM	-	-	-	NmrA-like family
HECICMKH_02261	1.25e-199	-	-	-	T	-	-	-	EAL domain
HECICMKH_02262	1.85e-121	-	-	-	-	-	-	-	-
HECICMKH_02263	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HECICMKH_02264	3.85e-159	-	-	-	E	-	-	-	Methionine synthase
HECICMKH_02265	5.47e-280	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HECICMKH_02266	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HECICMKH_02267	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HECICMKH_02268	2.18e-245	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HECICMKH_02269	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HECICMKH_02270	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HECICMKH_02271	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HECICMKH_02272	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HECICMKH_02273	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HECICMKH_02274	5.8e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HECICMKH_02275	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HECICMKH_02276	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HECICMKH_02277	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HECICMKH_02278	1.16e-242	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HECICMKH_02279	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HECICMKH_02280	3.44e-152	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HECICMKH_02281	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HECICMKH_02282	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HECICMKH_02283	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_02284	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HECICMKH_02285	4.76e-56	-	-	-	-	-	-	-	-
HECICMKH_02286	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HECICMKH_02287	3.21e-211	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_02288	5.66e-189	-	-	-	-	-	-	-	-
HECICMKH_02289	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
HECICMKH_02290	1.08e-47	-	-	-	-	-	-	-	-
HECICMKH_02291	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HECICMKH_02292	1.02e-113	-	-	-	-	-	-	-	-
HECICMKH_02293	1.4e-65	-	-	-	-	-	-	-	-
HECICMKH_02294	4.79e-13	-	-	-	-	-	-	-	-
HECICMKH_02295	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HECICMKH_02296	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HECICMKH_02297	1.52e-151	-	-	-	-	-	-	-	-
HECICMKH_02298	1.21e-69	-	-	-	-	-	-	-	-
HECICMKH_02300	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HECICMKH_02301	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HECICMKH_02302	1.1e-184	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HECICMKH_02303	2.38e-37	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HECICMKH_02304	1.76e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HECICMKH_02305	5.38e-131	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HECICMKH_02306	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HECICMKH_02307	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HECICMKH_02308	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HECICMKH_02309	6.01e-270	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HECICMKH_02310	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
HECICMKH_02311	1.58e-285	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HECICMKH_02312	3.74e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HECICMKH_02313	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HECICMKH_02314	2.13e-152	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_02315	9.76e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HECICMKH_02316	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HECICMKH_02317	9.53e-317	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HECICMKH_02318	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HECICMKH_02319	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HECICMKH_02320	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HECICMKH_02321	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HECICMKH_02322	3.03e-167	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HECICMKH_02323	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HECICMKH_02324	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HECICMKH_02325	7.63e-107	-	-	-	-	-	-	-	-
HECICMKH_02326	5.06e-196	-	-	-	S	-	-	-	hydrolase
HECICMKH_02327	1.51e-235	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HECICMKH_02328	2.8e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HECICMKH_02329	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HECICMKH_02330	3.78e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HECICMKH_02331	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HECICMKH_02332	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HECICMKH_02333	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HECICMKH_02334	1.08e-81	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HECICMKH_02335	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HECICMKH_02336	4.3e-44	-	-	-	-	-	-	-	-
HECICMKH_02337	4.93e-164	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HECICMKH_02338	0.0	ycaM	-	-	E	-	-	-	amino acid
HECICMKH_02339	2e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HECICMKH_02340	8.21e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HECICMKH_02341	5.11e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HECICMKH_02342	1.3e-209	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_02344	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HECICMKH_02345	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HECICMKH_02346	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HECICMKH_02347	1.54e-144	-	-	-	-	-	-	-	-
HECICMKH_02348	1.08e-243	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HECICMKH_02349	1.57e-184	-	-	-	S	-	-	-	Peptidase_C39 like family
HECICMKH_02350	8.1e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HECICMKH_02351	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HECICMKH_02352	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HECICMKH_02353	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HECICMKH_02354	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HECICMKH_02355	1.63e-238	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HECICMKH_02356	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_02357	1.12e-116	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HECICMKH_02358	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HECICMKH_02359	5.04e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HECICMKH_02360	1.14e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HECICMKH_02361	9.01e-155	-	-	-	S	-	-	-	Membrane
HECICMKH_02362	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HECICMKH_02363	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HECICMKH_02364	7.15e-260	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HECICMKH_02365	7.22e-163	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HECICMKH_02366	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HECICMKH_02367	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HECICMKH_02368	1.49e-131	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HECICMKH_02369	4.38e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HECICMKH_02370	8.39e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HECICMKH_02371	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HECICMKH_02372	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HECICMKH_02373	1.14e-79	-	-	-	M	-	-	-	LysM domain protein
HECICMKH_02374	2.72e-90	-	-	-	M	-	-	-	LysM domain
HECICMKH_02375	3.92e-120	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HECICMKH_02376	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_02377	6.76e-270	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HECICMKH_02378	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HECICMKH_02379	2e-73	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HECICMKH_02380	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HECICMKH_02381	1.27e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HECICMKH_02382	5.3e-302	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HECICMKH_02383	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HECICMKH_02384	2.03e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_02386	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HECICMKH_02387	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HECICMKH_02388	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HECICMKH_02389	2.82e-110	-	-	-	-	-	-	-	-
HECICMKH_02390	5.14e-111	yvbK	-	-	K	-	-	-	GNAT family
HECICMKH_02391	2.8e-49	-	-	-	-	-	-	-	-
HECICMKH_02392	2.81e-64	-	-	-	-	-	-	-	-
HECICMKH_02393	5.46e-145	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HECICMKH_02394	2.65e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HECICMKH_02395	1.57e-202	-	-	-	K	-	-	-	LysR substrate binding domain
HECICMKH_02396	2.53e-134	-	-	-	GM	-	-	-	NAD(P)H-binding
HECICMKH_02397	2.03e-248	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HECICMKH_02398	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HECICMKH_02399	1.15e-179	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HECICMKH_02400	2.92e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HECICMKH_02401	2.47e-97	-	-	-	C	-	-	-	Flavodoxin
HECICMKH_02402	1.38e-160	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
HECICMKH_02403	1.07e-116	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HECICMKH_02404	1.83e-111	-	-	-	GM	-	-	-	NAD(P)H-binding
HECICMKH_02405	7.86e-138	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HECICMKH_02406	5.63e-98	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_02408	1.03e-31	-	-	-	C	-	-	-	Flavodoxin
HECICMKH_02409	1.69e-08	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HECICMKH_02410	9.99e-147	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HECICMKH_02411	2.41e-165	-	-	-	C	-	-	-	Aldo keto reductase
HECICMKH_02412	4.02e-181	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HECICMKH_02413	3.08e-178	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
HECICMKH_02414	5.55e-106	-	-	-	GM	-	-	-	NAD(P)H-binding
HECICMKH_02415	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HECICMKH_02416	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HECICMKH_02417	2.4e-160	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HECICMKH_02418	1.12e-105	-	-	-	-	-	-	-	-
HECICMKH_02419	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HECICMKH_02420	3.45e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HECICMKH_02421	1.77e-130	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HECICMKH_02422	2.02e-246	-	-	-	C	-	-	-	Aldo/keto reductase family
HECICMKH_02424	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HECICMKH_02425	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HECICMKH_02426	5.46e-315	-	-	-	EGP	-	-	-	Major Facilitator
HECICMKH_02429	1.24e-229	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HECICMKH_02430	1.74e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HECICMKH_02431	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HECICMKH_02432	3.34e-199	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HECICMKH_02433	1.06e-138	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HECICMKH_02434	3.05e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HECICMKH_02435	9.53e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HECICMKH_02436	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HECICMKH_02437	4.68e-190	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HECICMKH_02438	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HECICMKH_02439	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HECICMKH_02440	2.33e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HECICMKH_02441	2.67e-220	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HECICMKH_02442	1.76e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HECICMKH_02443	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HECICMKH_02444	6.45e-203	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HECICMKH_02445	3.39e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HECICMKH_02446	0.0	-	-	-	-	-	-	-	-
HECICMKH_02447	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HECICMKH_02448	5.02e-117	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HECICMKH_02449	2.05e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HECICMKH_02450	2.23e-95	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HECICMKH_02451	3.1e-54	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HECICMKH_02452	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HECICMKH_02453	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HECICMKH_02454	1.56e-108	-	-	-	-	-	-	-	-
HECICMKH_02455	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HECICMKH_02456	5.32e-242	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HECICMKH_02457	2.09e-244	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HECICMKH_02458	3.7e-30	-	-	-	-	-	-	-	-
HECICMKH_02459	1.84e-134	-	-	-	-	-	-	-	-
HECICMKH_02460	2.09e-211	-	-	-	K	-	-	-	LysR substrate binding domain
HECICMKH_02461	1.24e-313	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HECICMKH_02462	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HECICMKH_02463	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HECICMKH_02464	3.22e-181	-	-	-	S	-	-	-	zinc-ribbon domain
HECICMKH_02466	4.29e-50	-	-	-	-	-	-	-	-
HECICMKH_02467	1.48e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HECICMKH_02468	4.07e-232	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HECICMKH_02469	0.0	-	-	-	I	-	-	-	acetylesterase activity
HECICMKH_02470	1.99e-297	-	-	-	M	-	-	-	Collagen binding domain
HECICMKH_02471	1.98e-205	yicL	-	-	EG	-	-	-	EamA-like transporter family
HECICMKH_02472	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HECICMKH_02473	1.44e-226	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HECICMKH_02474	3.29e-141	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HECICMKH_02475	3.57e-62	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HECICMKH_02476	2.52e-205	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HECICMKH_02477	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HECICMKH_02478	5.24e-124	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HECICMKH_02479	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
HECICMKH_02480	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HECICMKH_02481	2e-148	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HECICMKH_02482	2.48e-199	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HECICMKH_02483	7.28e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HECICMKH_02484	0.0	-	-	-	-	-	-	-	-
HECICMKH_02485	1.4e-82	-	-	-	-	-	-	-	-
HECICMKH_02486	9.55e-243	-	-	-	S	-	-	-	Cell surface protein
HECICMKH_02487	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HECICMKH_02488	1.91e-124	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HECICMKH_02489	1.61e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HECICMKH_02490	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HECICMKH_02491	3.79e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HECICMKH_02492	2.29e-195	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HECICMKH_02493	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HECICMKH_02495	1.15e-43	-	-	-	-	-	-	-	-
HECICMKH_02496	6.9e-168	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HECICMKH_02497	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HECICMKH_02498	1.69e-158	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HECICMKH_02499	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HECICMKH_02500	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HECICMKH_02501	2.87e-61	-	-	-	-	-	-	-	-
HECICMKH_02502	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HECICMKH_02503	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HECICMKH_02504	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HECICMKH_02505	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_02506	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HECICMKH_02507	2.03e-84	-	-	-	-	-	-	-	-
HECICMKH_02508	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HECICMKH_02509	2.86e-72	-	-	-	-	-	-	-	-
HECICMKH_02510	1.02e-193	-	-	-	K	-	-	-	Helix-turn-helix domain
HECICMKH_02511	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HECICMKH_02512	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HECICMKH_02513	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HECICMKH_02514	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HECICMKH_02515	3.04e-235	-	-	-	GM	-	-	-	Male sterility protein
HECICMKH_02516	4.4e-101	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HECICMKH_02517	4.61e-101	-	-	-	M	-	-	-	LysM domain
HECICMKH_02518	3.03e-130	-	-	-	M	-	-	-	Lysin motif
HECICMKH_02519	1.4e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
HECICMKH_02520	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HECICMKH_02521	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HECICMKH_02522	3.57e-120	-	-	-	-	-	-	-	-
HECICMKH_02523	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HECICMKH_02524	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
HECICMKH_02525	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HECICMKH_02526	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HECICMKH_02527	1.17e-214	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HECICMKH_02528	5.26e-96	-	-	-	-	-	-	-	-
HECICMKH_02529	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HECICMKH_02530	5.37e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HECICMKH_02531	2.51e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
HECICMKH_02532	1.6e-118	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HECICMKH_02533	5.51e-101	yphH	-	-	S	-	-	-	Cupin domain
HECICMKH_02534	2.06e-78	-	-	-	I	-	-	-	sulfurtransferase activity
HECICMKH_02535	5.44e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
HECICMKH_02536	8.38e-152	-	-	-	GM	-	-	-	NAD(P)H-binding
HECICMKH_02537	2.31e-277	-	-	-	-	-	-	-	-
HECICMKH_02538	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HECICMKH_02539	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_02540	1.3e-226	-	-	-	O	-	-	-	protein import
HECICMKH_02541	1.67e-292	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HECICMKH_02542	2.43e-208	yhxD	-	-	IQ	-	-	-	KR domain
HECICMKH_02544	9.38e-91	-	-	-	-	-	-	-	-
HECICMKH_02545	5.2e-187	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HECICMKH_02546	0.0	-	-	-	E	-	-	-	Amino Acid
HECICMKH_02547	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
HECICMKH_02548	6.97e-285	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HECICMKH_02549	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HECICMKH_02550	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HECICMKH_02551	1.49e-58	-	-	-	S	-	-	-	Cupredoxin-like domain
HECICMKH_02552	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HECICMKH_02553	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HECICMKH_02554	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HECICMKH_02555	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HECICMKH_02556	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HECICMKH_02557	0.0	-	-	-	-	-	-	-	-
HECICMKH_02558	3.15e-98	-	-	-	-	-	-	-	-
HECICMKH_02559	2.85e-243	-	-	-	S	-	-	-	Cell surface protein
HECICMKH_02560	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HECICMKH_02561	4.62e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HECICMKH_02562	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HECICMKH_02563	1.36e-148	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HECICMKH_02564	1.52e-241	ynjC	-	-	S	-	-	-	Cell surface protein
HECICMKH_02566	4.48e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HECICMKH_02567	9.96e-82	-	-	-	-	-	-	-	-
HECICMKH_02568	1.31e-301	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HECICMKH_02569	4.8e-156	-	-	-	-	-	-	-	-
HECICMKH_02570	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HECICMKH_02571	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HECICMKH_02572	1.81e-272	-	-	-	EGP	-	-	-	Major Facilitator
HECICMKH_02573	3.71e-146	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HECICMKH_02574	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HECICMKH_02575	1.38e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HECICMKH_02576	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HECICMKH_02577	1.31e-129	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_02578	5.35e-216	-	-	-	GM	-	-	-	NmrA-like family
HECICMKH_02579	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HECICMKH_02580	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HECICMKH_02581	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HECICMKH_02582	1.27e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HECICMKH_02583	3.27e-170	-	-	-	S	-	-	-	KR domain
HECICMKH_02584	2.46e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_02585	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HECICMKH_02586	1.09e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HECICMKH_02587	1.14e-228	ydhF	-	-	S	-	-	-	Aldo keto reductase
HECICMKH_02588	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
HECICMKH_02589	2.64e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_02590	1e-218	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HECICMKH_02591	6.37e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HECICMKH_02592	1.81e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HECICMKH_02593	8.17e-220	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HECICMKH_02594	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_02595	6.73e-211	-	-	-	GM	-	-	-	NmrA-like family
HECICMKH_02596	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HECICMKH_02597	1.4e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HECICMKH_02598	6.38e-195	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HECICMKH_02599	3.86e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HECICMKH_02600	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HECICMKH_02601	2.22e-235	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HECICMKH_02602	2.6e-114	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HECICMKH_02603	1.23e-268	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HECICMKH_02604	2.4e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_02605	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HECICMKH_02606	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HECICMKH_02607	3.73e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HECICMKH_02608	1.16e-209	-	-	-	K	-	-	-	LysR substrate binding domain
HECICMKH_02609	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HECICMKH_02610	0.0	-	-	-	S	-	-	-	MucBP domain
HECICMKH_02611	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HECICMKH_02612	1.9e-148	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HECICMKH_02613	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HECICMKH_02614	9.2e-317	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HECICMKH_02615	2.09e-85	-	-	-	-	-	-	-	-
HECICMKH_02616	5.15e-16	-	-	-	-	-	-	-	-
HECICMKH_02617	5.61e-54	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HECICMKH_02618	4.83e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HECICMKH_02619	5.98e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HECICMKH_02620	8.12e-282	-	-	-	S	-	-	-	Membrane
HECICMKH_02621	2.97e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HECICMKH_02622	5.35e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HECICMKH_02623	1.35e-55	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HECICMKH_02624	9.66e-77	-	-	-	-	-	-	-	-
HECICMKH_02625	2.06e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HECICMKH_02626	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HECICMKH_02627	9.09e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HECICMKH_02628	3.64e-47	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HECICMKH_02629	3.83e-48	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HECICMKH_02630	8.09e-142	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HECICMKH_02631	1.93e-139	-	-	-	GM	-	-	-	NAD(P)H-binding
HECICMKH_02632	5.35e-102	-	-	-	GM	-	-	-	SnoaL-like domain
HECICMKH_02633	0.0	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
HECICMKH_02634	2.52e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HECICMKH_02635	7.9e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_02636	1.34e-05	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HECICMKH_02637	8.53e-45	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HECICMKH_02639	6.79e-53	-	-	-	-	-	-	-	-
HECICMKH_02640	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HECICMKH_02641	9.26e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HECICMKH_02642	7.62e-270	xylR	-	-	GK	-	-	-	ROK family
HECICMKH_02643	4.93e-149	-	-	-	-	-	-	-	-
HECICMKH_02644	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HECICMKH_02645	1.41e-211	-	-	-	-	-	-	-	-
HECICMKH_02646	1.66e-259	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HECICMKH_02647	5.03e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HECICMKH_02648	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HECICMKH_02649	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HECICMKH_02650	2.12e-72	-	-	-	-	-	-	-	-
HECICMKH_02651	1.18e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HECICMKH_02652	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HECICMKH_02653	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HECICMKH_02654	1.66e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HECICMKH_02655	5.36e-305	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HECICMKH_02656	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HECICMKH_02657	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HECICMKH_02658	9.76e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HECICMKH_02659	3.84e-207	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HECICMKH_02660	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HECICMKH_02661	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HECICMKH_02662	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HECICMKH_02663	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HECICMKH_02664	3.98e-200	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HECICMKH_02665	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HECICMKH_02666	7.39e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HECICMKH_02667	3.66e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HECICMKH_02668	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HECICMKH_02669	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HECICMKH_02670	5.43e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HECICMKH_02671	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HECICMKH_02672	5.69e-300	-	-	-	EK	-	-	-	Aminotransferase, class I
HECICMKH_02673	1.29e-168	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HECICMKH_02674	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HECICMKH_02675	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HECICMKH_02676	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HECICMKH_02677	8.83e-127	-	-	-	KT	-	-	-	response to antibiotic
HECICMKH_02678	8.52e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HECICMKH_02679	6.03e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HECICMKH_02680	9.68e-202	-	-	-	S	-	-	-	Putative adhesin
HECICMKH_02681	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HECICMKH_02682	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HECICMKH_02683	1.06e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HECICMKH_02684	4.35e-262	-	-	-	S	-	-	-	DUF218 domain
HECICMKH_02685	9.95e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HECICMKH_02686	1.76e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HECICMKH_02687	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HECICMKH_02688	6.26e-101	-	-	-	-	-	-	-	-
HECICMKH_02689	5.43e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HECICMKH_02690	8.33e-189	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HECICMKH_02691	1.29e-115	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HECICMKH_02692	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HECICMKH_02693	6.69e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HECICMKH_02694	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HECICMKH_02695	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HECICMKH_02696	2.11e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HECICMKH_02697	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HECICMKH_02698	8.79e-199	-	-	-	GM	-	-	-	NmrA-like family
HECICMKH_02699	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HECICMKH_02700	5.93e-163	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HECICMKH_02702	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HECICMKH_02703	3.43e-303	-	-	-	S	-	-	-	module of peptide synthetase
HECICMKH_02704	4.71e-135	-	-	-	-	-	-	-	-
HECICMKH_02705	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HECICMKH_02706	7.43e-77	-	-	-	S	-	-	-	Enterocin A Immunity
HECICMKH_02707	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HECICMKH_02708	7.93e-217	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HECICMKH_02709	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HECICMKH_02710	9.76e-83	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HECICMKH_02711	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HECICMKH_02712	1.9e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HECICMKH_02713	1.03e-34	-	-	-	-	-	-	-	-
HECICMKH_02714	4.23e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HECICMKH_02716	6.99e-41	-	-	-	S	-	-	-	Haemolysin XhlA
HECICMKH_02717	4.06e-224	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HECICMKH_02718	4.46e-74	-	-	-	-	-	-	-	-
HECICMKH_02721	0.0	-	-	-	-	-	-	-	-
HECICMKH_02722	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HECICMKH_02723	2.19e-295	-	-	-	S	-	-	-	Phage tail protein
HECICMKH_02724	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HECICMKH_02725	5.58e-06	-	-	-	-	-	-	-	-
HECICMKH_02727	9.04e-92	-	-	-	S	-	-	-	Phage tail tube protein
HECICMKH_02729	1.62e-51	-	-	-	-	-	-	-	-
HECICMKH_02730	3.45e-32	-	-	-	S	-	-	-	Phage head-tail joining protein
HECICMKH_02731	3.93e-67	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HECICMKH_02732	2.01e-269	-	-	-	S	-	-	-	Phage capsid family
HECICMKH_02733	3.43e-155	-	-	-	S	-	-	-	Clp protease
HECICMKH_02734	4.31e-260	-	-	-	S	-	-	-	Phage portal protein
HECICMKH_02735	1.3e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
HECICMKH_02736	2.36e-219	-	-	-	S	-	-	-	Phage Terminase
HECICMKH_02737	5.71e-60	-	-	-	L	-	-	-	Phage terminase, small subunit
HECICMKH_02740	4.2e-117	-	-	-	L	-	-	-	HNH nucleases
HECICMKH_02741	1.54e-16	-	-	-	V	-	-	-	HNH nucleases
HECICMKH_02742	7.3e-84	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HECICMKH_02743	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HECICMKH_02744	5.87e-62	-	-	-	-	-	-	-	-
HECICMKH_02746	4.05e-209	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HECICMKH_02747	4.64e-98	-	-	-	L	-	-	-	DnaD domain protein
HECICMKH_02758	1.29e-34	-	-	-	S	-	-	-	Domain of unknown function (DUF1883)
HECICMKH_02760	2.64e-117	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
HECICMKH_02762	3.49e-30	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HECICMKH_02763	4.38e-48	-	-	-	S	-	-	-	Pfam:Peptidase_M78
HECICMKH_02764	2.89e-78	dinG	2.7.7.7, 3.6.4.12	-	L	ko:K02342,ko:K03722,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA-directed DNA polymerase activity
HECICMKH_02766	5.86e-31	-	-	-	-	-	-	-	-
HECICMKH_02771	2.13e-38	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HECICMKH_02772	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HECICMKH_02773	4.22e-212	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HECICMKH_02774	4.68e-235	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HECICMKH_02775	5.81e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HECICMKH_02776	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HECICMKH_02777	3.03e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HECICMKH_02778	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HECICMKH_02779	7.21e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HECICMKH_02780	1.45e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HECICMKH_02781	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HECICMKH_02783	1.88e-106	-	-	-	-	-	-	-	-
HECICMKH_02784	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HECICMKH_02786	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HECICMKH_02787	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HECICMKH_02788	1.54e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HECICMKH_02789	1.01e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HECICMKH_02790	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HECICMKH_02791	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HECICMKH_02792	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HECICMKH_02793	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HECICMKH_02794	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HECICMKH_02795	3.28e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HECICMKH_02797	2.77e-30	-	-	-	-	-	-	-	-
HECICMKH_02799	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HECICMKH_02800	4.79e-272	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HECICMKH_02801	4.4e-138	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HECICMKH_02802	1.83e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HECICMKH_02803	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HECICMKH_02804	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HECICMKH_02805	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HECICMKH_02806	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
HECICMKH_02807	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HECICMKH_02808	4.41e-316	-	-	-	EGP	-	-	-	Major Facilitator
HECICMKH_02810	4.54e-54	-	-	-	-	-	-	-	-
HECICMKH_02811	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HECICMKH_02812	3.74e-125	-	-	-	V	-	-	-	VanZ like family
HECICMKH_02813	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
HECICMKH_02814	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HECICMKH_02815	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HECICMKH_02816	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
HECICMKH_02817	1.05e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
HECICMKH_02818	3.15e-38	-	-	-	FG	-	-	-	HIT domain
HECICMKH_02819	3.23e-73	-	-	-	FG	-	-	-	HIT domain
HECICMKH_02820	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HECICMKH_02821	4.29e-101	-	-	-	-	-	-	-	-
HECICMKH_02822	3.73e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HECICMKH_02823	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HECICMKH_02824	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HECICMKH_02826	4.21e-158	-	-	-	S	-	-	-	YjbR
HECICMKH_02827	5.51e-284	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HECICMKH_02828	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HECICMKH_02829	7.12e-256	glmS2	-	-	M	-	-	-	SIS domain
HECICMKH_02830	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HECICMKH_02831	8.81e-37	-	-	-	S	-	-	-	Belongs to the LOG family
HECICMKH_02832	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HECICMKH_02833	2.71e-316	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HECICMKH_02834	2.65e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HECICMKH_02835	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HECICMKH_02836	3.9e-209	-	-	-	GM	-	-	-	NmrA-like family
HECICMKH_02837	2.71e-89	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HECICMKH_02838	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HECICMKH_02839	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HECICMKH_02840	1.7e-70	-	-	-	-	-	-	-	-
HECICMKH_02841	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HECICMKH_02842	2.11e-82	-	-	-	-	-	-	-	-
HECICMKH_02843	1.36e-112	-	-	-	-	-	-	-	-
HECICMKH_02844	3.22e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HECICMKH_02845	2.27e-74	-	-	-	-	-	-	-	-
HECICMKH_02846	4.79e-21	-	-	-	-	-	-	-	-
HECICMKH_02847	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HECICMKH_02848	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HECICMKH_02849	1.63e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HECICMKH_02850	2.66e-155	-	-	-	S	-	-	-	membrane
HECICMKH_02851	2.55e-145	-	-	-	S	-	-	-	VIT family
HECICMKH_02852	5.12e-242	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HECICMKH_02853	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HECICMKH_02854	4.83e-98	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HECICMKH_02855	4.26e-54	-	-	-	-	-	-	-	-
HECICMKH_02856	2.07e-97	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HECICMKH_02857	5.91e-313	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HECICMKH_02858	7.21e-35	-	-	-	-	-	-	-	-
HECICMKH_02859	2.55e-65	-	-	-	-	-	-	-	-
HECICMKH_02860	9.82e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HECICMKH_02861	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HECICMKH_02862	1.77e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HECICMKH_02863	4.21e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HECICMKH_02864	1.44e-99	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HECICMKH_02865	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HECICMKH_02866	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HECICMKH_02867	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HECICMKH_02868	8.02e-205	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HECICMKH_02869	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HECICMKH_02870	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HECICMKH_02871	2.07e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HECICMKH_02872	1.05e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HECICMKH_02873	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HECICMKH_02874	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
HECICMKH_02875	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HECICMKH_02876	1.58e-66	-	-	-	-	-	-	-	-
HECICMKH_02877	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HECICMKH_02878	0.0	-	-	-	-	-	-	-	-
HECICMKH_02879	1.36e-245	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HECICMKH_02880	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HECICMKH_02881	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HECICMKH_02882	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HECICMKH_02883	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_02884	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HECICMKH_02885	4.45e-38	-	-	-	-	-	-	-	-
HECICMKH_02886	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HECICMKH_02887	2.04e-107	-	-	-	M	-	-	-	PFAM NLP P60 protein
HECICMKH_02888	6.18e-71	-	-	-	-	-	-	-	-
HECICMKH_02889	5.77e-81	-	-	-	-	-	-	-	-
HECICMKH_02891	5.13e-138	-	-	-	-	-	-	-	-
HECICMKH_02892	1.43e-67	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HECICMKH_02893	5.87e-207	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HECICMKH_02894	1.37e-135	-	-	-	K	-	-	-	transcriptional regulator
HECICMKH_02895	1.02e-231	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HECICMKH_02896	1.39e-173	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HECICMKH_02897	3.04e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HECICMKH_02898	2.93e-234	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HECICMKH_02899	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HECICMKH_02900	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HECICMKH_02901	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HECICMKH_02902	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HECICMKH_02903	1.01e-26	-	-	-	-	-	-	-	-
HECICMKH_02904	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HECICMKH_02905	2.46e-43	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HECICMKH_02906	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HECICMKH_02907	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HECICMKH_02908	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HECICMKH_02909	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HECICMKH_02910	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HECICMKH_02911	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HECICMKH_02912	7.12e-159	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HECICMKH_02913	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HECICMKH_02914	7.83e-60	-	-	-	-	-	-	-	-
HECICMKH_02915	1.72e-135	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HECICMKH_02916	1.03e-65	-	-	-	-	-	-	-	-
HECICMKH_02917	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
HECICMKH_02918	4.03e-283	-	-	-	S	-	-	-	associated with various cellular activities
HECICMKH_02919	2.78e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HECICMKH_02920	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HECICMKH_02921	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HECICMKH_02922	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HECICMKH_02923	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HECICMKH_02924	4.73e-242	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HECICMKH_02925	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HECICMKH_02926	3.03e-295	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HECICMKH_02927	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HECICMKH_02928	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HECICMKH_02929	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HECICMKH_02930	1.12e-142	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HECICMKH_02931	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HECICMKH_02932	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HECICMKH_02933	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HECICMKH_02934	1.26e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HECICMKH_02935	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HECICMKH_02936	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HECICMKH_02937	6.68e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HECICMKH_02938	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HECICMKH_02939	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HECICMKH_02940	1.43e-251	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HECICMKH_02941	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HECICMKH_02942	5.16e-248	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HECICMKH_02943	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HECICMKH_02944	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HECICMKH_02945	2.49e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HECICMKH_02946	3.65e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HECICMKH_02947	7.89e-213	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HECICMKH_02948	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HECICMKH_02949	1.4e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HECICMKH_02950	2.83e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HECICMKH_02951	3.31e-205	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HECICMKH_02952	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HECICMKH_02953	5.56e-212	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HECICMKH_02954	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HECICMKH_02955	1.12e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HECICMKH_02956	2.09e-83	-	-	-	-	-	-	-	-
HECICMKH_02957	2.63e-200	estA	-	-	S	-	-	-	Putative esterase
HECICMKH_02958	9.03e-173	-	-	-	K	-	-	-	UTRA domain
HECICMKH_02959	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HECICMKH_02960	3.06e-212	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HECICMKH_02961	1.29e-206	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HECICMKH_02962	1.94e-270	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HECICMKH_02963	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HECICMKH_02964	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HECICMKH_02965	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HECICMKH_02966	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HECICMKH_02967	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HECICMKH_02968	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HECICMKH_02969	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HECICMKH_02970	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HECICMKH_02971	2.66e-222	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HECICMKH_02972	7.71e-250	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HECICMKH_02973	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HECICMKH_02975	4.02e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HECICMKH_02976	1.49e-185	yxeH	-	-	S	-	-	-	hydrolase
HECICMKH_02977	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HECICMKH_02978	8.34e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HECICMKH_02979	1.43e-306	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HECICMKH_02980	2.97e-60	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HECICMKH_02981	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HECICMKH_02982	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HECICMKH_02983	4.53e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HECICMKH_02984	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HECICMKH_02985	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HECICMKH_02986	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HECICMKH_02987	1.1e-103	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HECICMKH_02988	3.05e-161	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HECICMKH_02989	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HECICMKH_02990	1.09e-66	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HECICMKH_02991	4.84e-14	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HECICMKH_02992	6.83e-133	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HECICMKH_02993	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HECICMKH_02994	1.06e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HECICMKH_02995	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HECICMKH_02996	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HECICMKH_02997	3.44e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HECICMKH_02998	1.23e-158	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HECICMKH_02999	5.6e-292	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HECICMKH_03000	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HECICMKH_03001	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HECICMKH_03002	1.06e-16	-	-	-	-	-	-	-	-
HECICMKH_03003	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HECICMKH_03004	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HECICMKH_03005	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HECICMKH_03006	3.67e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HECICMKH_03007	7.01e-286	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HECICMKH_03008	7.72e-24	-	-	-	-	-	-	-	-
HECICMKH_03009	2.91e-125	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HECICMKH_03010	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HECICMKH_03012	1.97e-256	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HECICMKH_03013	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HECICMKH_03014	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_03015	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HECICMKH_03016	4.05e-81	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HECICMKH_03017	1.45e-162	-	-	-	S	-	-	-	Membrane
HECICMKH_03018	7.58e-210	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HECICMKH_03019	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
HECICMKH_03020	1.72e-73	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HECICMKH_03021	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HECICMKH_03022	9.42e-314	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HECICMKH_03023	1.44e-230	rhaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HECICMKH_03024	1.28e-180	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HECICMKH_03025	1.46e-60	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HECICMKH_03026	2.72e-126	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HECICMKH_03027	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
HECICMKH_03029	1.08e-208	-	-	-	-	-	-	-	-
HECICMKH_03030	2.76e-28	-	-	-	S	-	-	-	Cell surface protein
HECICMKH_03033	2.03e-12	-	-	-	L	-	-	-	Helix-turn-helix domain
HECICMKH_03034	4.32e-16	-	-	-	L	-	-	-	Helix-turn-helix domain
HECICMKH_03035	2.28e-22	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HECICMKH_03036	2.15e-17	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HECICMKH_03038	3.07e-06	-	-	-	D	-	-	-	Mycoplasma protein of unknown function, DUF285
HECICMKH_03040	1.62e-64	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HECICMKH_03041	3.08e-17	-	-	-	L	ko:K07487	-	ko00000	Transposase
HECICMKH_03043	2.12e-27	-	-	-	L	ko:K07487	-	ko00000	Transposase
HECICMKH_03044	9.07e-22	-	-	-	L	ko:K07487	-	ko00000	Transposase
HECICMKH_03045	9.47e-45	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HECICMKH_03046	9.95e-122	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HECICMKH_03047	1.12e-91	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HECICMKH_03048	3.68e-80	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HECICMKH_03049	1.75e-231	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HECICMKH_03050	4.02e-205	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HECICMKH_03051	0.0	-	2.3.1.204, 3.2.1.170, 3.2.1.24	GH38	G	ko:K01191,ko:K15524,ko:K16869	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolases family 38 N-terminal domain
HECICMKH_03052	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HECICMKH_03053	2.66e-248	-	-	-	K	-	-	-	Transcriptional regulator
HECICMKH_03054	0.0	ypdD	-	-	G	-	-	-	Glycosyl hydrolase family 92
HECICMKH_03055	1.81e-274	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HECICMKH_03056	3.76e-212	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HECICMKH_03057	0.0	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HECICMKH_03058	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HECICMKH_03059	1.71e-139	ypcB	-	-	S	-	-	-	integral membrane protein
HECICMKH_03060	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HECICMKH_03061	0.0	ypcG	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Domain of unknown function (DUF3502)
HECICMKH_03062	6.47e-213	lplC	-	-	U	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECICMKH_03063	1.29e-231	ypdA	-	-	U	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HECICMKH_03064	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HECICMKH_03065	9.5e-200	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HECICMKH_03066	0.0	mdlA2	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HECICMKH_03067	0.0	yknV	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HECICMKH_03068	1.48e-247	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HECICMKH_03069	1.57e-200	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HECICMKH_03070	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HECICMKH_03071	7.17e-234	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HECICMKH_03072	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HECICMKH_03073	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HECICMKH_03074	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HECICMKH_03075	2.21e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HECICMKH_03076	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HECICMKH_03077	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HECICMKH_03078	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HECICMKH_03079	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HECICMKH_03080	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HECICMKH_03081	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HECICMKH_03082	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HECICMKH_03083	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HECICMKH_03084	1.44e-185	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HECICMKH_03085	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HECICMKH_03086	3.3e-202	degV1	-	-	S	-	-	-	DegV family
HECICMKH_03087	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HECICMKH_03088	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HECICMKH_03090	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HECICMKH_03091	0.0	-	-	-	-	-	-	-	-
HECICMKH_03093	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HECICMKH_03094	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
HECICMKH_03095	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HECICMKH_03096	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HECICMKH_03097	2.37e-173	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HECICMKH_03098	2.26e-306	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HECICMKH_03099	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HECICMKH_03100	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HECICMKH_03101	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HECICMKH_03102	2.43e-173	repA	-	-	S	-	-	-	Replication initiator protein A
HECICMKH_03103	7.68e-39	-	-	-	-	-	-	-	-
HECICMKH_03104	1.55e-157	-	-	-	S	-	-	-	Fic/DOC family
HECICMKH_03105	2.01e-53	-	-	-	-	-	-	-	-
HECICMKH_03106	9.79e-37	-	-	-	-	-	-	-	-
HECICMKH_03107	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HECICMKH_03108	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HECICMKH_03109	7.02e-40	-	-	-	-	-	-	-	-
HECICMKH_03110	3.68e-240	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HECICMKH_03111	1.06e-260	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HECICMKH_03112	1.62e-150	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HECICMKH_03113	4.81e-281	-	-	-	EGP	-	-	-	Major Facilitator
HECICMKH_03115	8.76e-169	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
HECICMKH_03116	1.01e-158	-	-	-	E	ko:K03294	-	ko00000	Amino acid permease
HECICMKH_03117	7.14e-60	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HECICMKH_03118	1.17e-86	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HECICMKH_03119	4.45e-258	-	-	-	K	-	-	-	Sigma-54 interaction domain
HECICMKH_03120	7.49e-34	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HECICMKH_03121	5.12e-73	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HECICMKH_03122	2.48e-132	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
HECICMKH_03123	2.95e-143	-	-	-	G	ko:K19509	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HECICMKH_03124	1.33e-284	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HECICMKH_03125	8.43e-282	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HECICMKH_03126	3.04e-241	-	-	-	E	ko:K19956	ko00051,map00051	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HECICMKH_03127	1.5e-87	-	-	-	K	-	-	-	sugar-binding domain protein
HECICMKH_03128	2.36e-131	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HECICMKH_03129	6.03e-47	-	2.7.1.206	-	G	ko:K02812	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HECICMKH_03130	1.25e-83	-	2.7.1.206	-	G	ko:K02813	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HECICMKH_03131	2.89e-134	-	-	-	U	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HECICMKH_03132	5.34e-149	manZ	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HECICMKH_03134	6.46e-38	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HECICMKH_03135	7.7e-226	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HECICMKH_03137	3.75e-129	-	-	-	L	-	-	-	Resolvase, N terminal domain
HECICMKH_03138	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
HECICMKH_03139	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HECICMKH_03140	1.22e-91	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HECICMKH_03141	1.07e-86	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HECICMKH_03142	3.8e-67	-	-	-	L	-	-	-	recombinase activity
HECICMKH_03143	9.68e-15	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HECICMKH_03144	2.52e-213	-	-	-	P	-	-	-	Natural resistance-associated macrophage protein
HECICMKH_03145	2.93e-136	-	-	-	L	-	-	-	Resolvase, N terminal domain
HECICMKH_03146	1.51e-204	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HECICMKH_03147	3.16e-129	-	-	-	-	-	-	-	-
HECICMKH_03148	1.62e-157	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HECICMKH_03149	3.76e-99	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HECICMKH_03150	2.79e-07	-	-	-	-	-	-	-	-
HECICMKH_03151	1.9e-43	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HECICMKH_03152	1.46e-16	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HECICMKH_03155	4.17e-314	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HECICMKH_03157	5.49e-75	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HECICMKH_03158	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HECICMKH_03159	9.14e-64	-	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
HECICMKH_03162	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HECICMKH_03163	4.42e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_03164	8.87e-173	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HECICMKH_03167	1.55e-225	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HECICMKH_03168	9.45e-08	-	-	-	KT	-	-	-	LytTr DNA-binding domain
HECICMKH_03171	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HECICMKH_03172	3.24e-138	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HECICMKH_03173	8.7e-67	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HECICMKH_03174	5.63e-225	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HECICMKH_03175	2.03e-31	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
HECICMKH_03176	1.18e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HECICMKH_03177	5.3e-49	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HECICMKH_03178	6.94e-59	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HECICMKH_03179	1.03e-107	-	-	-	-	-	-	-	-
HECICMKH_03180	5.76e-53	-	-	-	-	-	-	-	-
HECICMKH_03181	6.17e-31	-	-	-	-	-	-	-	-
HECICMKH_03182	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HECICMKH_03184	4.16e-104	-	-	-	-	-	-	-	-
HECICMKH_03185	4.45e-66	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
HECICMKH_03186	2.56e-69	-	-	-	-	-	-	-	-
HECICMKH_03187	3.84e-153	-	-	-	-	-	-	-	-
HECICMKH_03188	0.0	-	-	-	U	-	-	-	AAA-like domain
HECICMKH_03189	0.0	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HECICMKH_03190	4.55e-208	-	-	-	M	-	-	-	CHAP domain
HECICMKH_03191	1.53e-76	-	-	-	-	-	-	-	-
HECICMKH_03192	9.67e-59	-	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HECICMKH_03193	3.88e-87	-	-	-	-	-	-	-	-
HECICMKH_03194	9.16e-295	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
HECICMKH_03196	2.5e-97	-	-	-	-	-	-	-	-
HECICMKH_03197	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HECICMKH_03198	1.85e-44	-	-	-	-	-	-	-	-
HECICMKH_03199	2.43e-245	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HECICMKH_03200	1.91e-215	-	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HECICMKH_03201	2.05e-81	-	-	-	-	-	-	-	-
HECICMKH_03202	3.2e-70	-	-	-	-	-	-	-	-
HECICMKH_03203	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HECICMKH_03205	5.88e-53	-	-	-	-	-	-	-	-
HECICMKH_03206	8.95e-171	-	-	-	L	-	-	-	LlaJI restriction endonuclease
HECICMKH_03207	1.16e-225	-	-	-	V	-	-	-	AAA domain (dynein-related subfamily)
HECICMKH_03208	9.33e-224	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HECICMKH_03210	2.44e-28	-	-	-	L	-	-	-	DNA binding domain, excisionase family
HECICMKH_03211	1.16e-156	-	-	-	L	-	-	-	DNA restriction-modification system
HECICMKH_03212	2.52e-207	-	-	-	H	-	-	-	C-5 cytosine-specific DNA methylase
HECICMKH_03213	9.33e-224	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HECICMKH_03214	4.83e-228	iunH5	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
HECICMKH_03215	5.46e-126	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HECICMKH_03216	1.1e-22	-	-	-	L	-	-	-	Replication protein