ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
DHGIOLOB_00001 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
DHGIOLOB_00002 1.64e-120 - - - M - - - FR47-like protein
DHGIOLOB_00003 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
DHGIOLOB_00004 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
DHGIOLOB_00005 1.95e-109 yuaE - - S - - - DinB superfamily
DHGIOLOB_00006 5.8e-137 yuaD - - - - - - -
DHGIOLOB_00007 1e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
DHGIOLOB_00008 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
DHGIOLOB_00009 3.39e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
DHGIOLOB_00010 5.83e-118 yuaB - - - - - - -
DHGIOLOB_00011 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
DHGIOLOB_00012 3.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
DHGIOLOB_00013 3.31e-52 yubF - - S - - - yiaA/B two helix domain
DHGIOLOB_00014 2.18e-195 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DHGIOLOB_00015 0.0 yubD - - P - - - Major Facilitator Superfamily
DHGIOLOB_00016 6.82e-114 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
DHGIOLOB_00018 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DHGIOLOB_00019 8.95e-255 yubA - - S - - - transporter activity
DHGIOLOB_00020 1.45e-232 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
DHGIOLOB_00021 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
DHGIOLOB_00022 2.86e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
DHGIOLOB_00023 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
DHGIOLOB_00024 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
DHGIOLOB_00025 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
DHGIOLOB_00026 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
DHGIOLOB_00027 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
DHGIOLOB_00028 1.2e-297 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
DHGIOLOB_00029 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
DHGIOLOB_00030 2.41e-178 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
DHGIOLOB_00031 3.52e-48 - - - - - - - -
DHGIOLOB_00032 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
DHGIOLOB_00033 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
DHGIOLOB_00034 5.09e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
DHGIOLOB_00035 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
DHGIOLOB_00036 6.2e-48 - - - - - - - -
DHGIOLOB_00037 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
DHGIOLOB_00038 2.92e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
DHGIOLOB_00039 4.22e-95 yugN - - S - - - YugN-like family
DHGIOLOB_00041 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
DHGIOLOB_00042 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
DHGIOLOB_00043 8.16e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
DHGIOLOB_00044 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
DHGIOLOB_00045 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
DHGIOLOB_00046 1.56e-254 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
DHGIOLOB_00047 6.74e-112 alaR - - K - - - Transcriptional regulator
DHGIOLOB_00048 9.89e-201 yugF - - I - - - Hydrolase
DHGIOLOB_00049 1.53e-52 yugE - - S - - - Domain of unknown function (DUF1871)
DHGIOLOB_00050 9.13e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
DHGIOLOB_00051 3.04e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_00052 2.49e-91 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
DHGIOLOB_00053 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
DHGIOLOB_00055 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
DHGIOLOB_00056 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
DHGIOLOB_00057 1.92e-97 yuxK - - S - - - protein conserved in bacteria
DHGIOLOB_00058 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
DHGIOLOB_00059 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
DHGIOLOB_00060 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
DHGIOLOB_00061 9.13e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
DHGIOLOB_00062 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_00063 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
DHGIOLOB_00064 6.97e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
DHGIOLOB_00065 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
DHGIOLOB_00066 1.73e-22 - - - - - - - -
DHGIOLOB_00067 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
DHGIOLOB_00068 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DHGIOLOB_00069 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DHGIOLOB_00070 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DHGIOLOB_00071 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DHGIOLOB_00072 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
DHGIOLOB_00073 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
DHGIOLOB_00074 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
DHGIOLOB_00075 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DHGIOLOB_00076 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_00078 7.01e-183 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
DHGIOLOB_00079 6.29e-10 - - - S - - - DegQ (SacQ) family
DHGIOLOB_00080 4.38e-09 yuzC - - - - - - -
DHGIOLOB_00081 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
DHGIOLOB_00082 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DHGIOLOB_00083 2.69e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
DHGIOLOB_00084 3.11e-87 - - - S - - - Protein of unknown function (DUF1694)
DHGIOLOB_00085 1.63e-52 yueH - - S - - - YueH-like protein
DHGIOLOB_00086 1.19e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
DHGIOLOB_00087 1.35e-244 yueF - - S - - - transporter activity
DHGIOLOB_00088 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
DHGIOLOB_00089 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
DHGIOLOB_00090 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
DHGIOLOB_00091 3.53e-170 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DHGIOLOB_00092 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
DHGIOLOB_00093 0.0 yueB - - S - - - type VII secretion protein EsaA
DHGIOLOB_00094 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
DHGIOLOB_00095 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
DHGIOLOB_00096 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
DHGIOLOB_00097 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
DHGIOLOB_00098 5.72e-290 yukF - - QT - - - Transcriptional regulator
DHGIOLOB_00099 1.64e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
DHGIOLOB_00100 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
DHGIOLOB_00101 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
DHGIOLOB_00102 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHGIOLOB_00103 6.09e-226 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
DHGIOLOB_00104 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
DHGIOLOB_00105 2.45e-289 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
DHGIOLOB_00106 2.89e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGIOLOB_00107 1.04e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
DHGIOLOB_00108 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
DHGIOLOB_00109 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
DHGIOLOB_00110 4.25e-278 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
DHGIOLOB_00111 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DHGIOLOB_00112 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
DHGIOLOB_00113 1.5e-149 yuiC - - S - - - protein conserved in bacteria
DHGIOLOB_00114 9.78e-47 yuiB - - S - - - Putative membrane protein
DHGIOLOB_00115 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
DHGIOLOB_00116 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
DHGIOLOB_00118 3.7e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DHGIOLOB_00119 2.84e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
DHGIOLOB_00120 1.39e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DHGIOLOB_00121 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
DHGIOLOB_00122 2.25e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DHGIOLOB_00123 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DHGIOLOB_00124 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
DHGIOLOB_00125 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
DHGIOLOB_00126 2.7e-74 yuzD - - S - - - protein conserved in bacteria
DHGIOLOB_00127 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
DHGIOLOB_00128 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
DHGIOLOB_00129 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DHGIOLOB_00130 1.14e-251 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DHGIOLOB_00131 6.79e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
DHGIOLOB_00132 4.63e-255 yutH - - S - - - Spore coat protein
DHGIOLOB_00133 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
DHGIOLOB_00134 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DHGIOLOB_00135 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
DHGIOLOB_00136 3.2e-63 yutD - - S - - - protein conserved in bacteria
DHGIOLOB_00137 2.71e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DHGIOLOB_00138 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DHGIOLOB_00139 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
DHGIOLOB_00140 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
DHGIOLOB_00141 8.06e-64 yunC - - S - - - Domain of unknown function (DUF1805)
DHGIOLOB_00142 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
DHGIOLOB_00143 1.86e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
DHGIOLOB_00144 7.07e-219 yunF - - S - - - Protein of unknown function DUF72
DHGIOLOB_00145 5.95e-77 yunG - - - - - - -
DHGIOLOB_00146 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
DHGIOLOB_00147 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
DHGIOLOB_00148 6.93e-299 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
DHGIOLOB_00149 1.84e-282 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
DHGIOLOB_00150 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
DHGIOLOB_00151 1.47e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
DHGIOLOB_00152 2.95e-123 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
DHGIOLOB_00153 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
DHGIOLOB_00154 4.27e-188 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
DHGIOLOB_00155 7.22e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
DHGIOLOB_00156 4.85e-232 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DHGIOLOB_00157 5.74e-304 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
DHGIOLOB_00158 3.96e-293 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
DHGIOLOB_00159 4.42e-216 bsn - - L - - - Ribonuclease
DHGIOLOB_00160 2.95e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DHGIOLOB_00161 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
DHGIOLOB_00162 7.86e-208 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
DHGIOLOB_00163 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
DHGIOLOB_00164 1.44e-198 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
DHGIOLOB_00165 9.59e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
DHGIOLOB_00166 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
DHGIOLOB_00167 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
DHGIOLOB_00168 4.87e-260 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
DHGIOLOB_00170 3.35e-56 - - - - - - - -
DHGIOLOB_00171 5.06e-86 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DHGIOLOB_00172 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
DHGIOLOB_00173 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
DHGIOLOB_00174 1.14e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DHGIOLOB_00175 3.53e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
DHGIOLOB_00176 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
DHGIOLOB_00177 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DHGIOLOB_00178 8.33e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
DHGIOLOB_00179 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
DHGIOLOB_00180 3.05e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DHGIOLOB_00181 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
DHGIOLOB_00182 8.14e-73 yusE - - CO - - - Thioredoxin
DHGIOLOB_00183 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
DHGIOLOB_00184 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
DHGIOLOB_00185 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
DHGIOLOB_00186 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
DHGIOLOB_00187 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
DHGIOLOB_00188 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
DHGIOLOB_00189 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
DHGIOLOB_00190 1.11e-13 - - - S - - - YuzL-like protein
DHGIOLOB_00191 6.98e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
DHGIOLOB_00192 4.51e-54 - - - - - - - -
DHGIOLOB_00193 8.66e-70 yusN - - M - - - Coat F domain
DHGIOLOB_00194 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
DHGIOLOB_00195 0.0 yusP - - P - - - Major facilitator superfamily
DHGIOLOB_00196 1.7e-84 yusQ - - S - - - Tautomerase enzyme
DHGIOLOB_00197 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGIOLOB_00198 8.42e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
DHGIOLOB_00199 3.01e-63 yusU - - S - - - Protein of unknown function (DUF2573)
DHGIOLOB_00200 2.51e-195 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
DHGIOLOB_00201 3.48e-88 - - - S - - - YusW-like protein
DHGIOLOB_00202 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
DHGIOLOB_00203 7.45e-195 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGIOLOB_00204 2.15e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
DHGIOLOB_00205 1.12e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DHGIOLOB_00206 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DHGIOLOB_00207 2.77e-316 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_00208 3.06e-204 yuxN - - K - - - Transcriptional regulator
DHGIOLOB_00209 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DHGIOLOB_00210 2.6e-33 - - - S - - - Protein of unknown function (DUF3970)
DHGIOLOB_00211 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
DHGIOLOB_00212 9.28e-250 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
DHGIOLOB_00213 1.76e-242 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
DHGIOLOB_00214 6.34e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DHGIOLOB_00215 2.25e-243 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_00216 2.1e-161 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
DHGIOLOB_00217 5.74e-172 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
DHGIOLOB_00218 9.94e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
DHGIOLOB_00219 4.68e-79 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
DHGIOLOB_00220 6.23e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_00221 8.2e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
DHGIOLOB_00222 2.12e-308 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
DHGIOLOB_00223 7.4e-234 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHGIOLOB_00224 1.36e-214 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
DHGIOLOB_00225 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGIOLOB_00226 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
DHGIOLOB_00227 0.0 yvrG - - T - - - Histidine kinase
DHGIOLOB_00228 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DHGIOLOB_00229 6.16e-33 - - - - - - - -
DHGIOLOB_00230 4.06e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
DHGIOLOB_00231 3.46e-26 - - - S - - - YvrJ protein family
DHGIOLOB_00232 2.17e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
DHGIOLOB_00233 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
DHGIOLOB_00234 7.7e-273 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
DHGIOLOB_00235 1.09e-157 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_00236 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
DHGIOLOB_00237 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
DHGIOLOB_00238 3.22e-224 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHGIOLOB_00239 1.72e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHGIOLOB_00240 3.13e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DHGIOLOB_00242 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
DHGIOLOB_00243 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
DHGIOLOB_00244 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
DHGIOLOB_00245 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
DHGIOLOB_00246 4.91e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
DHGIOLOB_00247 1.22e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
DHGIOLOB_00248 1.43e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
DHGIOLOB_00249 1.77e-200 yvgN - - S - - - reductase
DHGIOLOB_00250 9.32e-112 yvgO - - - - - - -
DHGIOLOB_00251 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
DHGIOLOB_00252 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
DHGIOLOB_00253 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DHGIOLOB_00254 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
DHGIOLOB_00256 2.34e-139 yvgT - - S - - - membrane
DHGIOLOB_00257 5.7e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
DHGIOLOB_00258 3.45e-137 bdbD - - O - - - Thioredoxin
DHGIOLOB_00259 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
DHGIOLOB_00260 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
DHGIOLOB_00261 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
DHGIOLOB_00262 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
DHGIOLOB_00263 2.95e-249 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
DHGIOLOB_00264 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DHGIOLOB_00265 0.0 - - - S - - - Fusaric acid resistance protein-like
DHGIOLOB_00266 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
DHGIOLOB_00267 2.38e-69 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
DHGIOLOB_00268 5.77e-127 - - - K - - - Bacterial regulatory proteins, tetR family
DHGIOLOB_00269 2.01e-140 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGIOLOB_00270 1.07e-29 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGIOLOB_00271 4.89e-22 - - - - - - - -
DHGIOLOB_00274 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DHGIOLOB_00275 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DHGIOLOB_00276 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
DHGIOLOB_00277 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
DHGIOLOB_00278 8.14e-196 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
DHGIOLOB_00279 4.9e-48 yvzC - - K - - - transcriptional
DHGIOLOB_00280 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
DHGIOLOB_00281 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
DHGIOLOB_00282 3.85e-72 yvaP - - K - - - transcriptional
DHGIOLOB_00283 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
DHGIOLOB_00284 2.54e-195 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
DHGIOLOB_00285 1.41e-135 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
DHGIOLOB_00286 2.99e-103 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
DHGIOLOB_00287 1.67e-110 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
DHGIOLOB_00288 7.1e-131 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_00291 1.18e-97 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
DHGIOLOB_00292 8.57e-193 - - - V ko:K06147,ko:K06148,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
DHGIOLOB_00293 1.04e-231 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
DHGIOLOB_00294 2.48e-134 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
DHGIOLOB_00295 2.27e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DHGIOLOB_00296 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
DHGIOLOB_00297 2.02e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
DHGIOLOB_00298 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
DHGIOLOB_00299 5.59e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
DHGIOLOB_00300 7.4e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DHGIOLOB_00301 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
DHGIOLOB_00302 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
DHGIOLOB_00303 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
DHGIOLOB_00304 9.68e-136 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
DHGIOLOB_00305 2.96e-145 yvbH - - S - - - YvbH-like oligomerisation region
DHGIOLOB_00306 1.13e-156 yvbI - - M - - - Membrane
DHGIOLOB_00307 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
DHGIOLOB_00308 9.77e-106 yvbK - - K - - - acetyltransferase
DHGIOLOB_00309 3.94e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DHGIOLOB_00310 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
DHGIOLOB_00311 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DHGIOLOB_00312 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
DHGIOLOB_00313 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DHGIOLOB_00314 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
DHGIOLOB_00315 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DHGIOLOB_00316 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
DHGIOLOB_00317 1.21e-244 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DHGIOLOB_00318 4.9e-206 yvbU - - K - - - Transcriptional regulator
DHGIOLOB_00319 2.27e-197 yvbV - - EG - - - EamA-like transporter family
DHGIOLOB_00320 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
DHGIOLOB_00321 7.05e-248 - - - S - - - Glycosyl hydrolase
DHGIOLOB_00322 8.37e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
DHGIOLOB_00323 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
DHGIOLOB_00324 9.08e-175 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
DHGIOLOB_00325 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DHGIOLOB_00326 1.8e-250 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_00327 2.04e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
DHGIOLOB_00328 1.5e-202 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
DHGIOLOB_00330 2.08e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
DHGIOLOB_00331 2.51e-264 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
DHGIOLOB_00332 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
DHGIOLOB_00333 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
DHGIOLOB_00334 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
DHGIOLOB_00335 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
DHGIOLOB_00336 4.62e-292 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
DHGIOLOB_00337 2.72e-234 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_00338 2.79e-145 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
DHGIOLOB_00339 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
DHGIOLOB_00340 6.75e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
DHGIOLOB_00341 5.69e-44 yvfG - - S - - - YvfG protein
DHGIOLOB_00342 1.1e-233 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
DHGIOLOB_00343 1.76e-277 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
DHGIOLOB_00344 1.22e-82 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
DHGIOLOB_00345 9.14e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
DHGIOLOB_00346 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DHGIOLOB_00347 6.76e-246 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
DHGIOLOB_00348 7.76e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
DHGIOLOB_00349 6.04e-249 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
DHGIOLOB_00350 8.82e-265 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
DHGIOLOB_00351 4.67e-280 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
DHGIOLOB_00352 1.25e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
DHGIOLOB_00353 1.28e-213 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
DHGIOLOB_00354 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
DHGIOLOB_00355 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
DHGIOLOB_00356 1.61e-157 epsA - - M ko:K19420 - ko00000 biosynthesis protein
DHGIOLOB_00357 1.24e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
DHGIOLOB_00358 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
DHGIOLOB_00360 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
DHGIOLOB_00361 1.75e-93 - - - S - - - Protein of unknown function (DUF3237)
DHGIOLOB_00362 2.06e-161 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
DHGIOLOB_00363 0.0 pbpE - - V - - - Beta-lactamase
DHGIOLOB_00364 7.19e-86 - - - - - - - -
DHGIOLOB_00365 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
DHGIOLOB_00366 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
DHGIOLOB_00367 0.0 ybeC - - E - - - amino acid
DHGIOLOB_00368 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
DHGIOLOB_00369 1.49e-66 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
DHGIOLOB_00370 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
DHGIOLOB_00371 1.12e-121 yvdQ - - S - - - Protein of unknown function (DUF3231)
DHGIOLOB_00373 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DHGIOLOB_00374 2.27e-148 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
DHGIOLOB_00375 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
DHGIOLOB_00376 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
DHGIOLOB_00377 5.26e-202 malA - - S - - - Protein of unknown function (DUF1189)
DHGIOLOB_00378 6.84e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
DHGIOLOB_00379 3.37e-308 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
DHGIOLOB_00380 4.02e-300 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
DHGIOLOB_00381 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
DHGIOLOB_00382 1.54e-221 yvdE - - K - - - Transcriptional regulator
DHGIOLOB_00383 6.28e-136 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
DHGIOLOB_00384 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
DHGIOLOB_00385 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
DHGIOLOB_00386 8.79e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
DHGIOLOB_00387 2.7e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHGIOLOB_00388 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
DHGIOLOB_00389 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_00390 9.29e-250 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
DHGIOLOB_00391 3.84e-171 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DHGIOLOB_00392 7.95e-45 - - - - - - - -
DHGIOLOB_00393 8.02e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
DHGIOLOB_00394 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
DHGIOLOB_00395 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
DHGIOLOB_00396 3.19e-225 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
DHGIOLOB_00397 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
DHGIOLOB_00398 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
DHGIOLOB_00399 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DHGIOLOB_00400 3.05e-190 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
DHGIOLOB_00401 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
DHGIOLOB_00402 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
DHGIOLOB_00404 0.0 - - - - - - - -
DHGIOLOB_00405 2.8e-27 - - - - - - - -
DHGIOLOB_00406 1.06e-110 - - - - - - - -
DHGIOLOB_00407 2e-72 - - - - - - - -
DHGIOLOB_00408 1.34e-75 - - - - - - - -
DHGIOLOB_00409 7.95e-116 - - - S - - - Predicted membrane protein (DUF2339)
DHGIOLOB_00410 3.68e-141 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
DHGIOLOB_00411 2.29e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DHGIOLOB_00412 7.64e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DHGIOLOB_00413 8.08e-147 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DHGIOLOB_00414 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
DHGIOLOB_00415 1.05e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DHGIOLOB_00416 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
DHGIOLOB_00417 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DHGIOLOB_00418 2.14e-179 yvpB - - NU - - - protein conserved in bacteria
DHGIOLOB_00419 1.05e-151 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
DHGIOLOB_00420 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
DHGIOLOB_00421 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
DHGIOLOB_00422 2.06e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
DHGIOLOB_00423 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DHGIOLOB_00424 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DHGIOLOB_00425 2.81e-278 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
DHGIOLOB_00426 1.95e-162 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DHGIOLOB_00427 3.02e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
DHGIOLOB_00428 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
DHGIOLOB_00429 4.13e-104 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
DHGIOLOB_00430 9.32e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
DHGIOLOB_00431 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
DHGIOLOB_00432 1.03e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
DHGIOLOB_00433 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
DHGIOLOB_00434 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
DHGIOLOB_00435 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
DHGIOLOB_00436 5.54e-219 yvlB - - S - - - Putative adhesin
DHGIOLOB_00437 8.09e-65 yvlA - - - - - - -
DHGIOLOB_00438 2.25e-45 yvkN - - - - - - -
DHGIOLOB_00439 1.68e-157 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DHGIOLOB_00440 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DHGIOLOB_00441 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DHGIOLOB_00442 2.54e-42 csbA - - S - - - protein conserved in bacteria
DHGIOLOB_00443 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
DHGIOLOB_00444 4.09e-131 yvkB - - K - - - Transcriptional regulator
DHGIOLOB_00445 1.23e-294 yvkA - - P - - - -transporter
DHGIOLOB_00446 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DHGIOLOB_00447 1.38e-73 swrA - - S - - - Swarming motility protein
DHGIOLOB_00448 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
DHGIOLOB_00449 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
DHGIOLOB_00450 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
DHGIOLOB_00451 3.78e-74 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
DHGIOLOB_00452 1.86e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
DHGIOLOB_00453 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DHGIOLOB_00454 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DHGIOLOB_00455 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DHGIOLOB_00456 9.14e-88 - - - - - - - -
DHGIOLOB_00457 1.73e-08 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
DHGIOLOB_00458 2.1e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
DHGIOLOB_00459 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DHGIOLOB_00460 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
DHGIOLOB_00461 3.11e-143 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DHGIOLOB_00462 1.23e-39 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DHGIOLOB_00463 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DHGIOLOB_00464 1.7e-92 yviE - - - - - - -
DHGIOLOB_00465 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
DHGIOLOB_00466 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
DHGIOLOB_00467 9.24e-98 yvyG - - NOU - - - FlgN protein
DHGIOLOB_00468 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
DHGIOLOB_00469 1.83e-96 yvyF - - S - - - flagellar protein
DHGIOLOB_00470 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
DHGIOLOB_00471 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
DHGIOLOB_00472 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DHGIOLOB_00473 2.51e-198 degV - - S - - - protein conserved in bacteria
DHGIOLOB_00474 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DHGIOLOB_00475 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
DHGIOLOB_00476 1.94e-136 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
DHGIOLOB_00477 1.23e-151 - - - K - - - Transcriptional regulator
DHGIOLOB_00481 2.9e-50 - - - S - - - Psort location CytoplasmicMembrane, score
DHGIOLOB_00484 6.05e-100 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_00486 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
DHGIOLOB_00487 3.69e-300 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
DHGIOLOB_00488 7.68e-174 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
DHGIOLOB_00489 9.78e-136 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
DHGIOLOB_00490 9.1e-315 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
DHGIOLOB_00491 2.01e-302 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DHGIOLOB_00492 4.27e-257 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
DHGIOLOB_00493 1.28e-300 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DHGIOLOB_00494 2.13e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
DHGIOLOB_00495 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
DHGIOLOB_00496 0.0 lytB - - D - - - Stage II sporulation protein
DHGIOLOB_00497 1.39e-15 - - - - - - - -
DHGIOLOB_00498 2.52e-40 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
DHGIOLOB_00499 4.48e-22 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
DHGIOLOB_00500 2.43e-264 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DHGIOLOB_00501 1.64e-204 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
DHGIOLOB_00502 1.74e-13 - - - L - - - COG2963 Transposase and inactivated derivatives
DHGIOLOB_00503 2.7e-204 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
DHGIOLOB_00504 3.02e-171 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
DHGIOLOB_00507 0.0 tagF2 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DHGIOLOB_00508 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DHGIOLOB_00509 2.4e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
DHGIOLOB_00510 5.03e-183 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
DHGIOLOB_00511 1.5e-257 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DHGIOLOB_00512 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DHGIOLOB_00513 4.34e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
DHGIOLOB_00514 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
DHGIOLOB_00515 1.48e-248 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
DHGIOLOB_00516 1.03e-262 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
DHGIOLOB_00517 1.06e-313 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DHGIOLOB_00518 1.67e-176 ywtF_2 - - K - - - Transcriptional regulator
DHGIOLOB_00519 3.3e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
DHGIOLOB_00520 5.14e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
DHGIOLOB_00521 2.29e-29 ywtC - - - - - - -
DHGIOLOB_00522 1.1e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
DHGIOLOB_00523 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
DHGIOLOB_00524 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
DHGIOLOB_00525 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
DHGIOLOB_00526 6.18e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DHGIOLOB_00527 6.55e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
DHGIOLOB_00528 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
DHGIOLOB_00529 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
DHGIOLOB_00530 2.59e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
DHGIOLOB_00531 4.83e-120 batE - - T - - - Sh3 type 3 domain protein
DHGIOLOB_00532 1.53e-62 ywsA - - S - - - Protein of unknown function (DUF3892)
DHGIOLOB_00533 2.15e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
DHGIOLOB_00534 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
DHGIOLOB_00535 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
DHGIOLOB_00536 9.64e-218 alsR - - K - - - LysR substrate binding domain
DHGIOLOB_00537 4.82e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DHGIOLOB_00538 2.5e-161 ywrJ - - - - - - -
DHGIOLOB_00539 1.95e-194 cotB - - - ko:K06325 - ko00000 -
DHGIOLOB_00540 1.2e-264 cotH - - M ko:K06330 - ko00000 Spore Coat
DHGIOLOB_00541 1.03e-17 - - - - - - - -
DHGIOLOB_00542 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DHGIOLOB_00543 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
DHGIOLOB_00544 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
DHGIOLOB_00545 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
DHGIOLOB_00546 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
DHGIOLOB_00547 4.99e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
DHGIOLOB_00549 3.68e-130 ywqN - - S - - - NAD(P)H-dependent
DHGIOLOB_00550 2.34e-209 - - - K - - - Transcriptional regulator
DHGIOLOB_00551 4.92e-154 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
DHGIOLOB_00552 1.15e-67 - - - - - - - -
DHGIOLOB_00553 4.03e-10 - - - - - - - -
DHGIOLOB_00555 4.61e-66 - - - - - - - -
DHGIOLOB_00556 1.01e-61 - - - - - - - -
DHGIOLOB_00557 2.05e-312 ywqJ - - S - - - Pre-toxin TG
DHGIOLOB_00558 2.17e-52 ywqI - - S - - - Family of unknown function (DUF5344)
DHGIOLOB_00560 4.19e-196 ywqG - - S - - - Domain of unknown function (DUF1963)
DHGIOLOB_00561 4.66e-313 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DHGIOLOB_00562 5.87e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
DHGIOLOB_00563 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
DHGIOLOB_00564 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
DHGIOLOB_00565 3.6e-25 - - - - - - - -
DHGIOLOB_00566 0.0 ywqB - - S - - - SWIM zinc finger
DHGIOLOB_00567 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
DHGIOLOB_00568 5.07e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
DHGIOLOB_00569 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
DHGIOLOB_00570 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
DHGIOLOB_00571 5.26e-88 ywpG - - - - - - -
DHGIOLOB_00572 2.53e-88 ywpF - - S - - - YwpF-like protein
DHGIOLOB_00573 5.03e-108 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
DHGIOLOB_00574 0.0 - - - M - - - cell wall anchor domain
DHGIOLOB_00575 4.13e-222 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
DHGIOLOB_00576 0.0 ywpD - - T - - - Histidine kinase
DHGIOLOB_00577 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DHGIOLOB_00578 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DHGIOLOB_00579 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
DHGIOLOB_00580 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
DHGIOLOB_00581 9.79e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
DHGIOLOB_00582 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
DHGIOLOB_00583 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
DHGIOLOB_00584 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
DHGIOLOB_00585 5.56e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_00586 1.19e-311 ywoF - - P - - - Right handed beta helix region
DHGIOLOB_00587 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
DHGIOLOB_00588 8.92e-306 ywoD - - EGP - - - Major facilitator superfamily
DHGIOLOB_00589 2.56e-134 yjgF - - Q - - - Isochorismatase family
DHGIOLOB_00590 2.4e-101 - - - - - - - -
DHGIOLOB_00591 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
DHGIOLOB_00592 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
DHGIOLOB_00593 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
DHGIOLOB_00594 4.49e-93 ywnJ - - S - - - VanZ like family
DHGIOLOB_00595 2.63e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
DHGIOLOB_00596 3.65e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
DHGIOLOB_00597 6.95e-21 ywnC - - S - - - Family of unknown function (DUF5362)
DHGIOLOB_00598 4.73e-234 - - - M - - - NeuB family
DHGIOLOB_00599 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
DHGIOLOB_00600 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DHGIOLOB_00601 4.46e-180 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
DHGIOLOB_00602 1.24e-77 ywnC - - S - - - Family of unknown function (DUF5362)
DHGIOLOB_00603 1.69e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
DHGIOLOB_00604 4.58e-85 ywnA - - K - - - Transcriptional regulator
DHGIOLOB_00605 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
DHGIOLOB_00606 3.2e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
DHGIOLOB_00607 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
DHGIOLOB_00608 5.51e-28 - - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
DHGIOLOB_00609 1.11e-21 csbD - - K - - - CsbD-like
DHGIOLOB_00610 7.7e-110 ywmF - - S - - - Peptidase M50
DHGIOLOB_00612 3.1e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
DHGIOLOB_00613 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DHGIOLOB_00614 5.24e-186 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DHGIOLOB_00616 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
DHGIOLOB_00617 1.56e-156 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
DHGIOLOB_00618 1.97e-233 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
DHGIOLOB_00619 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DHGIOLOB_00620 8.01e-173 ywmB - - S - - - TATA-box binding
DHGIOLOB_00621 4.54e-45 ywzB - - S - - - membrane
DHGIOLOB_00622 1.76e-114 ywmA - - - - - - -
DHGIOLOB_00623 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
DHGIOLOB_00624 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DHGIOLOB_00625 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DHGIOLOB_00626 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DHGIOLOB_00627 7.94e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DHGIOLOB_00628 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DHGIOLOB_00629 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DHGIOLOB_00630 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
DHGIOLOB_00631 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
DHGIOLOB_00632 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DHGIOLOB_00633 5.09e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DHGIOLOB_00634 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
DHGIOLOB_00635 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
DHGIOLOB_00636 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DHGIOLOB_00637 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
DHGIOLOB_00638 8.25e-248 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DHGIOLOB_00639 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
DHGIOLOB_00640 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
DHGIOLOB_00641 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
DHGIOLOB_00643 8.46e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DHGIOLOB_00644 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DHGIOLOB_00645 6.62e-87 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DHGIOLOB_00646 2.93e-108 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
DHGIOLOB_00647 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
DHGIOLOB_00648 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
DHGIOLOB_00649 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
DHGIOLOB_00650 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
DHGIOLOB_00651 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DHGIOLOB_00652 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
DHGIOLOB_00653 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DHGIOLOB_00654 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DHGIOLOB_00655 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
DHGIOLOB_00656 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
DHGIOLOB_00657 3.86e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
DHGIOLOB_00658 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DHGIOLOB_00659 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DHGIOLOB_00660 2.98e-269 acdA - - I - - - acyl-CoA dehydrogenase
DHGIOLOB_00661 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
DHGIOLOB_00662 1.42e-288 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
DHGIOLOB_00663 6.65e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
DHGIOLOB_00664 1.32e-57 ywjC - - - - - - -
DHGIOLOB_00665 2.08e-117 ywjB - - H - - - RibD C-terminal domain
DHGIOLOB_00666 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
DHGIOLOB_00667 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DHGIOLOB_00668 2.06e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
DHGIOLOB_00669 2.28e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
DHGIOLOB_00670 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
DHGIOLOB_00671 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DHGIOLOB_00672 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
DHGIOLOB_00673 1.84e-179 ywiC - - S - - - YwiC-like protein
DHGIOLOB_00674 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
DHGIOLOB_00675 1.2e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
DHGIOLOB_00676 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
DHGIOLOB_00677 1.51e-66 ywiB - - S - - - protein conserved in bacteria
DHGIOLOB_00678 3.71e-12 - - - S - - - Bacteriocin subtilosin A
DHGIOLOB_00679 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
DHGIOLOB_00681 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
DHGIOLOB_00682 5.92e-298 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
DHGIOLOB_00683 1.7e-276 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
DHGIOLOB_00684 1.09e-313 - - - L - - - Peptidase, M16
DHGIOLOB_00686 3.67e-272 ywhK - - CO - - - amine dehydrogenase activity
DHGIOLOB_00687 9.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
DHGIOLOB_00689 1.09e-32 - - - S - - - Aminoacyl-tRNA editing domain
DHGIOLOB_00690 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
DHGIOLOB_00691 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DHGIOLOB_00692 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
DHGIOLOB_00693 1.21e-63 - - - - - - - -
DHGIOLOB_00694 9.14e-122 ywhD - - S - - - YwhD family
DHGIOLOB_00695 3.29e-154 ywhC - - S - - - Peptidase family M50
DHGIOLOB_00696 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
DHGIOLOB_00697 1.45e-93 ywhA - - K - - - Transcriptional regulator
DHGIOLOB_00698 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DHGIOLOB_00700 1.15e-301 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
DHGIOLOB_00701 4.3e-101 yffB - - K - - - Transcriptional regulator
DHGIOLOB_00702 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
DHGIOLOB_00703 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
DHGIOLOB_00704 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
DHGIOLOB_00705 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
DHGIOLOB_00706 3.8e-196 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
DHGIOLOB_00707 1.77e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
DHGIOLOB_00708 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_00709 1.37e-223 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
DHGIOLOB_00710 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
DHGIOLOB_00711 2.37e-176 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
DHGIOLOB_00712 2.21e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
DHGIOLOB_00713 3.74e-266 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
DHGIOLOB_00714 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
DHGIOLOB_00715 3.14e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DHGIOLOB_00716 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
DHGIOLOB_00717 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
DHGIOLOB_00718 4.44e-274 ywfA - - EGP - - - -transporter
DHGIOLOB_00719 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
DHGIOLOB_00720 0.0 rocB - - E - - - arginine degradation protein
DHGIOLOB_00721 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
DHGIOLOB_00722 6.05e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
DHGIOLOB_00723 1.51e-100 - - - - - - - -
DHGIOLOB_00724 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
DHGIOLOB_00725 2.44e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DHGIOLOB_00726 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DHGIOLOB_00727 6.13e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DHGIOLOB_00728 5.26e-236 spsG - - M - - - Spore Coat
DHGIOLOB_00729 1.23e-164 spsF - - M ko:K07257 - ko00000 Spore Coat
DHGIOLOB_00730 2.27e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
DHGIOLOB_00731 4.22e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
DHGIOLOB_00732 3.73e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
DHGIOLOB_00733 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
DHGIOLOB_00734 8.08e-187 spsA - - M - - - Spore Coat
DHGIOLOB_00735 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
DHGIOLOB_00736 1.59e-78 ywdK - - S - - - small membrane protein
DHGIOLOB_00737 1.86e-303 ywdJ - - F - - - Xanthine uracil
DHGIOLOB_00738 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
DHGIOLOB_00739 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
DHGIOLOB_00740 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DHGIOLOB_00741 3.84e-191 ywdF - - S - - - Glycosyltransferase like family 2
DHGIOLOB_00742 6.07e-185 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
DHGIOLOB_00743 6.19e-39 ywdA - - - - - - -
DHGIOLOB_00744 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
DHGIOLOB_00745 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DHGIOLOB_00746 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
DHGIOLOB_00747 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
DHGIOLOB_00749 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
DHGIOLOB_00750 4.19e-239 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DHGIOLOB_00751 1.98e-179 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
DHGIOLOB_00752 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
DHGIOLOB_00753 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
DHGIOLOB_00754 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
DHGIOLOB_00755 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
DHGIOLOB_00756 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DHGIOLOB_00757 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
DHGIOLOB_00758 5.11e-49 ydaS - - S - - - membrane
DHGIOLOB_00759 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
DHGIOLOB_00760 5.56e-291 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DHGIOLOB_00761 3.33e-77 gtcA - - S - - - GtrA-like protein
DHGIOLOB_00762 2.41e-158 ywcC - - K - - - transcriptional regulator
DHGIOLOB_00764 1.23e-63 ywcB - - S - - - Protein of unknown function, DUF485
DHGIOLOB_00765 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DHGIOLOB_00766 7.65e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
DHGIOLOB_00767 1.26e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
DHGIOLOB_00768 4.87e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
DHGIOLOB_00769 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
DHGIOLOB_00770 2.57e-148 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DHGIOLOB_00771 6.56e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DHGIOLOB_00772 2.7e-203 ywbI - - K - - - Transcriptional regulator
DHGIOLOB_00773 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
DHGIOLOB_00774 1.21e-143 ywbG - - M - - - effector of murein hydrolase
DHGIOLOB_00775 1.29e-280 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
DHGIOLOB_00776 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
DHGIOLOB_00777 1.15e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
DHGIOLOB_00778 4.01e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
DHGIOLOB_00779 3.56e-161 ywbB - - S - - - Protein of unknown function (DUF2711)
DHGIOLOB_00780 1.22e-309 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHGIOLOB_00781 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
DHGIOLOB_00782 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DHGIOLOB_00783 9.07e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
DHGIOLOB_00784 6.53e-217 gspA - - M - - - General stress
DHGIOLOB_00785 8.81e-152 ywaF - - S - - - Integral membrane protein
DHGIOLOB_00786 1.25e-114 ywaE - - K - - - Transcriptional regulator
DHGIOLOB_00787 8.66e-295 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DHGIOLOB_00788 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
DHGIOLOB_00789 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
DHGIOLOB_00790 5.1e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
DHGIOLOB_00791 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
DHGIOLOB_00792 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHGIOLOB_00793 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
DHGIOLOB_00794 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHGIOLOB_00795 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DHGIOLOB_00796 2.91e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGIOLOB_00797 1.77e-262 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
DHGIOLOB_00798 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
DHGIOLOB_00799 1.3e-49 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DHGIOLOB_00800 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHGIOLOB_00801 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
DHGIOLOB_00802 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
DHGIOLOB_00803 8.94e-28 yxzF - - - - - - -
DHGIOLOB_00804 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
DHGIOLOB_00805 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
DHGIOLOB_00806 1.95e-271 yxlH - - EGP - - - Major Facilitator Superfamily
DHGIOLOB_00807 9.33e-178 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
DHGIOLOB_00808 8.18e-211 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_00809 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
DHGIOLOB_00810 1.63e-39 - - - - - - - -
DHGIOLOB_00811 5.53e-62 yxlC - - S - - - Family of unknown function (DUF5345)
DHGIOLOB_00812 1.29e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DHGIOLOB_00813 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
DHGIOLOB_00814 9.16e-203 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DHGIOLOB_00815 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
DHGIOLOB_00816 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
DHGIOLOB_00817 9.56e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
DHGIOLOB_00818 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
DHGIOLOB_00819 2.67e-308 cimH - - C - - - COG3493 Na citrate symporter
DHGIOLOB_00820 0.0 - - - O - - - Peptidase family M48
DHGIOLOB_00822 5.28e-199 yxkH - - G - - - Polysaccharide deacetylase
DHGIOLOB_00823 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DHGIOLOB_00824 1.58e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
DHGIOLOB_00825 1.64e-166 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DHGIOLOB_00826 8.4e-133 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DHGIOLOB_00827 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
DHGIOLOB_00828 1.74e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
DHGIOLOB_00829 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
DHGIOLOB_00830 2.09e-244 - - - T - - - Signal transduction histidine kinase
DHGIOLOB_00831 1.23e-144 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
DHGIOLOB_00832 1.83e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
DHGIOLOB_00834 4.98e-112 yxjI - - S - - - LURP-one-related
DHGIOLOB_00835 2.48e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
DHGIOLOB_00836 1.49e-273 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
DHGIOLOB_00837 2.77e-174 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
DHGIOLOB_00838 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
DHGIOLOB_00839 4.46e-166 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DHGIOLOB_00840 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
DHGIOLOB_00841 1.63e-199 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
DHGIOLOB_00842 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DHGIOLOB_00843 1.47e-133 - - - T - - - Domain of unknown function (DUF4163)
DHGIOLOB_00844 6.3e-61 yxiS - - - - - - -
DHGIOLOB_00845 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
DHGIOLOB_00846 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
DHGIOLOB_00847 2.07e-182 bglS - - M - - - licheninase activity
DHGIOLOB_00848 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
DHGIOLOB_00849 5.32e-143 - - - - - - - -
DHGIOLOB_00850 3.8e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
DHGIOLOB_00851 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
DHGIOLOB_00852 6.52e-270 - - - E - - - GDSL-like Lipase/Acylhydrolase
DHGIOLOB_00855 3.48e-59 yxiJ - - S - - - YxiJ-like protein
DHGIOLOB_00858 7.33e-43 - - - - - - - -
DHGIOLOB_00859 4.1e-111 yxiI - - S - - - Protein of unknown function (DUF2716)
DHGIOLOB_00860 2.41e-173 - - - - - - - -
DHGIOLOB_00863 6.09e-50 - - - S - - - Protein of unknown function (DUF2750)
DHGIOLOB_00864 3.95e-67 yxxG - - - - - - -
DHGIOLOB_00865 1.9e-88 yxiG - - - - - - -
DHGIOLOB_00866 3.76e-66 - - - - - - - -
DHGIOLOB_00867 3.53e-100 - - - - - - - -
DHGIOLOB_00868 8.9e-119 - - - S - - - Protein of unknown function (DUF4240)
DHGIOLOB_00869 8.76e-176 - - - - - - - -
DHGIOLOB_00872 5.46e-101 wapA - - M - - - COG3209 Rhs family protein
DHGIOLOB_00873 3.29e-19 yxiJ - - S - - - YxiJ-like protein
DHGIOLOB_00874 0.0 wapA - - M - - - COG3209 Rhs family protein
DHGIOLOB_00875 2.94e-210 yxxF - - EG - - - EamA-like transporter family
DHGIOLOB_00876 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
DHGIOLOB_00877 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
DHGIOLOB_00878 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DHGIOLOB_00879 9.21e-44 - - - - - - - -
DHGIOLOB_00880 1.03e-167 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
DHGIOLOB_00881 3.27e-53 yxiC - - S - - - Family of unknown function (DUF5344)
DHGIOLOB_00882 5.38e-37 - - - S - - - Domain of unknown function (DUF5082)
DHGIOLOB_00883 0.0 - - - L - - - HKD family nuclease
DHGIOLOB_00884 1.23e-78 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
DHGIOLOB_00885 3.11e-193 - - - L - - - Protein of unknown function (DUF2726)
DHGIOLOB_00886 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
DHGIOLOB_00887 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
DHGIOLOB_00888 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
DHGIOLOB_00889 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DHGIOLOB_00890 8.72e-297 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
DHGIOLOB_00891 8.04e-230 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
DHGIOLOB_00892 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
DHGIOLOB_00893 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
DHGIOLOB_00894 2.72e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DHGIOLOB_00895 2.38e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DHGIOLOB_00896 4.26e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
DHGIOLOB_00897 1.51e-196 - - - S - - - Domain of Unknown Function (DUF1206)
DHGIOLOB_00898 2.21e-255 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
DHGIOLOB_00899 1.33e-310 yxeQ - - S - - - MmgE/PrpD family
DHGIOLOB_00900 3.37e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
DHGIOLOB_00901 6.82e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_00902 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
DHGIOLOB_00903 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
DHGIOLOB_00904 2.19e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DHGIOLOB_00905 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DHGIOLOB_00906 2.61e-235 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
DHGIOLOB_00907 2.71e-192 yxeH - - S - - - hydrolases of the HAD superfamily
DHGIOLOB_00910 7.32e-42 yxeE - - - - - - -
DHGIOLOB_00911 7.57e-28 yxeD - - - - - - -
DHGIOLOB_00912 9.65e-91 - - - - - - - -
DHGIOLOB_00913 9.65e-223 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DHGIOLOB_00914 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
DHGIOLOB_00915 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
DHGIOLOB_00916 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_00917 4.47e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_00918 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DHGIOLOB_00919 2.83e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
DHGIOLOB_00920 3.26e-193 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
DHGIOLOB_00921 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
DHGIOLOB_00922 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
DHGIOLOB_00923 4.19e-298 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
DHGIOLOB_00924 4.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
DHGIOLOB_00925 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
DHGIOLOB_00926 1.23e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
DHGIOLOB_00927 4.9e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
DHGIOLOB_00928 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DHGIOLOB_00929 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
DHGIOLOB_00930 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
DHGIOLOB_00932 1.23e-63 yxcD - - S - - - Protein of unknown function (DUF2653)
DHGIOLOB_00933 4.16e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DHGIOLOB_00934 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
DHGIOLOB_00936 8.38e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
DHGIOLOB_00937 1.03e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
DHGIOLOB_00938 2.4e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
DHGIOLOB_00939 1.79e-43 yxaI - - S - - - membrane protein domain
DHGIOLOB_00940 4.24e-78 - - - S - - - Family of unknown function (DUF5391)
DHGIOLOB_00941 2.49e-31 yxaI - - S - - - membrane protein domain
DHGIOLOB_00942 8.75e-51 yxaI - - S - - - membrane protein domain
DHGIOLOB_00943 4.89e-282 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
DHGIOLOB_00944 3.65e-251 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
DHGIOLOB_00945 9.61e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
DHGIOLOB_00946 1.5e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGIOLOB_00947 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
DHGIOLOB_00948 5.96e-77 - - - S ko:K06518 - ko00000,ko02000 LrgA family
DHGIOLOB_00949 5.16e-152 yxaC - - M - - - effector of murein hydrolase
DHGIOLOB_00950 2.01e-242 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
DHGIOLOB_00951 1.35e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
DHGIOLOB_00952 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
DHGIOLOB_00953 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
DHGIOLOB_00954 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
DHGIOLOB_00955 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DHGIOLOB_00956 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
DHGIOLOB_00957 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
DHGIOLOB_00958 9.2e-197 - - - - - - - -
DHGIOLOB_00959 3.34e-24 - - - - - - - -
DHGIOLOB_00960 1.44e-24 - - - - - - - -
DHGIOLOB_00961 1.11e-151 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
DHGIOLOB_00962 2.41e-142 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DHGIOLOB_00963 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
DHGIOLOB_00964 2.9e-64 - - - L - - - Recombinase zinc beta ribbon domain
DHGIOLOB_00965 3.23e-220 - - - V ko:K07448 - ko00000,ko02048 Restriction endonuclease
DHGIOLOB_00966 2.23e-11 spoIVCA - - L ko:K06400 - ko00000 Recombinase
DHGIOLOB_00967 1.17e-90 spoIVCA - - L ko:K06400 - ko00000 Recombinase
DHGIOLOB_00968 8.44e-21 spoIVCA - - L ko:K06400 - ko00000 Recombinase
DHGIOLOB_00969 7.1e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DHGIOLOB_00971 6.92e-82 - - - - - - - -
DHGIOLOB_00972 4.43e-89 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
DHGIOLOB_00973 1.96e-169 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
DHGIOLOB_00975 8.79e-38 yycQ - - S - - - Protein of unknown function (DUF2651)
DHGIOLOB_00976 2.39e-258 yycP - - - - - - -
DHGIOLOB_00977 2.78e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DHGIOLOB_00978 2.6e-111 yycN - - K - - - Acetyltransferase
DHGIOLOB_00979 2.38e-236 - - - S - - - aspartate phosphatase
DHGIOLOB_00981 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
DHGIOLOB_00982 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
DHGIOLOB_00983 2.89e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
DHGIOLOB_00984 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
DHGIOLOB_00985 9.43e-279 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DHGIOLOB_00986 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
DHGIOLOB_00987 1.2e-200 yycI - - S - - - protein conserved in bacteria
DHGIOLOB_00988 0.0 yycH - - S - - - protein conserved in bacteria
DHGIOLOB_00989 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_00990 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DHGIOLOB_00995 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DHGIOLOB_00996 1.34e-98 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DHGIOLOB_00997 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
DHGIOLOB_00998 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
DHGIOLOB_01000 1.89e-22 yycC - - K - - - YycC-like protein
DHGIOLOB_01001 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
DHGIOLOB_01002 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DHGIOLOB_01003 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
DHGIOLOB_01004 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
DHGIOLOB_01005 7.43e-205 yybS - - S - - - membrane
DHGIOLOB_01007 5.61e-108 cotF - - M ko:K06329 - ko00000 Spore coat protein
DHGIOLOB_01008 6.68e-90 yybR - - K - - - Transcriptional regulator
DHGIOLOB_01009 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
DHGIOLOB_01010 2.34e-92 - - - - - - - -
DHGIOLOB_01012 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_01013 4.38e-142 - - - K - - - TipAS antibiotic-recognition domain
DHGIOLOB_01014 6.12e-185 - - - - - - - -
DHGIOLOB_01015 3.02e-88 - - - S - - - SnoaL-like domain
DHGIOLOB_01016 1.89e-160 yybG - - S - - - Pentapeptide repeat-containing protein
DHGIOLOB_01017 4.31e-277 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_01018 2.53e-208 yybE - - K - - - Transcriptional regulator
DHGIOLOB_01019 2.55e-100 yjcF - - S - - - Acetyltransferase (GNAT) domain
DHGIOLOB_01020 1.22e-97 yybC - - - - - - -
DHGIOLOB_01021 2.16e-164 - - - S - - - Metallo-beta-lactamase superfamily
DHGIOLOB_01022 4.54e-100 yybA - - K - - - transcriptional
DHGIOLOB_01023 1.16e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
DHGIOLOB_01024 4.28e-125 yyaS - - S ko:K07149 - ko00000 Membrane
DHGIOLOB_01025 2.07e-123 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
DHGIOLOB_01026 1.09e-87 - - - S - - - YjbR
DHGIOLOB_01027 2.2e-139 yyaP - - H - - - RibD C-terminal domain
DHGIOLOB_01028 1.29e-18 yddB - - S - - - Conjugative transposon protein TcpC
DHGIOLOB_01031 1.3e-58 yddA - - - - - - -
DHGIOLOB_01036 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
DHGIOLOB_01037 8.91e-217 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
DHGIOLOB_01038 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
DHGIOLOB_01039 1.14e-130 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
DHGIOLOB_01040 7.2e-90 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DHGIOLOB_01041 3.03e-230 ccpB - - K - - - Transcriptional regulator
DHGIOLOB_01042 2.07e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
DHGIOLOB_01043 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DHGIOLOB_01044 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DHGIOLOB_01045 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
DHGIOLOB_01046 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DHGIOLOB_01047 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DHGIOLOB_01048 7.41e-45 yyzM - - S - - - protein conserved in bacteria
DHGIOLOB_01049 5.34e-227 yyaD - - S - - - Membrane
DHGIOLOB_01050 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
DHGIOLOB_01051 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
DHGIOLOB_01052 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
DHGIOLOB_01053 2.27e-98 - - - S - - - Bacterial PH domain
DHGIOLOB_01054 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
DHGIOLOB_01055 1.68e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
DHGIOLOB_01056 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DHGIOLOB_01057 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DHGIOLOB_01058 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
DHGIOLOB_01059 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DHGIOLOB_01060 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DHGIOLOB_01061 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DHGIOLOB_01062 2.06e-258 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DHGIOLOB_01063 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
DHGIOLOB_01064 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DHGIOLOB_01065 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
DHGIOLOB_01066 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DHGIOLOB_01067 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DHGIOLOB_01068 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
DHGIOLOB_01069 2.72e-148 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
DHGIOLOB_01070 1.76e-138 - - - - - - - -
DHGIOLOB_01071 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DHGIOLOB_01072 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DHGIOLOB_01073 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
DHGIOLOB_01074 1.2e-30 ymzA - - - - - - -
DHGIOLOB_01075 1.63e-31 - - - - - - - -
DHGIOLOB_01076 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
DHGIOLOB_01077 1.38e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DHGIOLOB_01078 5.41e-76 ymaF - - S - - - YmaF family
DHGIOLOB_01080 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
DHGIOLOB_01081 2.23e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
DHGIOLOB_01082 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
DHGIOLOB_01083 3.96e-163 ymaC - - S - - - Replication protein
DHGIOLOB_01085 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
DHGIOLOB_01086 2.67e-207 - - - S - - - Metallo-beta-lactamase superfamily
DHGIOLOB_01087 8.03e-81 ymzB - - - - - - -
DHGIOLOB_01088 1.24e-135 pksA - - K - - - Transcriptional regulator
DHGIOLOB_01089 2.67e-125 ymcC - - S - - - Membrane
DHGIOLOB_01091 1.91e-91 - - - S - - - Regulatory protein YrvL
DHGIOLOB_01092 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DHGIOLOB_01093 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DHGIOLOB_01094 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
DHGIOLOB_01095 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
DHGIOLOB_01096 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DHGIOLOB_01097 1.89e-274 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
DHGIOLOB_01098 8.31e-253 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
DHGIOLOB_01099 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
DHGIOLOB_01100 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
DHGIOLOB_01101 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
DHGIOLOB_01102 1.82e-276 pbpX - - V - - - Beta-lactamase
DHGIOLOB_01103 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DHGIOLOB_01104 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
DHGIOLOB_01105 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DHGIOLOB_01106 8.75e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
DHGIOLOB_01107 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
DHGIOLOB_01108 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
DHGIOLOB_01109 1.49e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
DHGIOLOB_01110 5.35e-306 ymfH - - S - - - zinc protease
DHGIOLOB_01111 3.31e-299 albE - - S - - - Peptidase M16
DHGIOLOB_01112 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_01113 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_01114 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
DHGIOLOB_01115 4.94e-44 - - - S - - - YlzJ-like protein
DHGIOLOB_01116 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
DHGIOLOB_01117 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DHGIOLOB_01118 6.39e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DHGIOLOB_01119 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
DHGIOLOB_01120 5.56e-246 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DHGIOLOB_01121 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
DHGIOLOB_01122 1.52e-207 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
DHGIOLOB_01123 1.53e-56 ymxH - - S - - - YlmC YmxH family
DHGIOLOB_01124 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
DHGIOLOB_01125 2.4e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
DHGIOLOB_01126 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DHGIOLOB_01127 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DHGIOLOB_01128 2.22e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
DHGIOLOB_01129 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DHGIOLOB_01130 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DHGIOLOB_01131 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
DHGIOLOB_01132 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DHGIOLOB_01133 6.16e-63 ylxQ - - J - - - ribosomal protein
DHGIOLOB_01134 1.66e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
DHGIOLOB_01135 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
DHGIOLOB_01136 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
DHGIOLOB_01137 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DHGIOLOB_01138 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DHGIOLOB_01139 4.72e-285 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
DHGIOLOB_01140 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
DHGIOLOB_01141 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
DHGIOLOB_01142 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DHGIOLOB_01143 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DHGIOLOB_01144 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
DHGIOLOB_01145 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DHGIOLOB_01146 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
DHGIOLOB_01147 1.15e-99 ylxL - - - - - - -
DHGIOLOB_01148 1.33e-175 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DHGIOLOB_01149 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
DHGIOLOB_01150 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
DHGIOLOB_01151 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
DHGIOLOB_01152 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
DHGIOLOB_01153 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
DHGIOLOB_01154 4.46e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
DHGIOLOB_01155 5.42e-254 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
DHGIOLOB_01156 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DHGIOLOB_01157 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DHGIOLOB_01158 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
DHGIOLOB_01159 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
DHGIOLOB_01160 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
DHGIOLOB_01161 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
DHGIOLOB_01162 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
DHGIOLOB_01163 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DHGIOLOB_01164 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
DHGIOLOB_01165 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
DHGIOLOB_01166 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
DHGIOLOB_01167 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
DHGIOLOB_01168 2.61e-304 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
DHGIOLOB_01169 1.51e-78 ylxF - - S - - - MgtE intracellular N domain
DHGIOLOB_01170 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
DHGIOLOB_01171 1e-306 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
DHGIOLOB_01172 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
DHGIOLOB_01173 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
DHGIOLOB_01174 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
DHGIOLOB_01175 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
DHGIOLOB_01176 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
DHGIOLOB_01177 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
DHGIOLOB_01178 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DHGIOLOB_01179 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DHGIOLOB_01180 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DHGIOLOB_01181 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
DHGIOLOB_01182 2.59e-312 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DHGIOLOB_01183 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DHGIOLOB_01184 3.62e-215 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
DHGIOLOB_01185 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DHGIOLOB_01186 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
DHGIOLOB_01187 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
DHGIOLOB_01188 0.0 ylqG - - - - - - -
DHGIOLOB_01189 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DHGIOLOB_01190 2.83e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DHGIOLOB_01191 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DHGIOLOB_01192 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
DHGIOLOB_01193 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DHGIOLOB_01194 9.77e-80 ylqD - - S - - - YlqD protein
DHGIOLOB_01195 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
DHGIOLOB_01196 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
DHGIOLOB_01197 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DHGIOLOB_01198 8.01e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DHGIOLOB_01199 1.67e-114 - - - - - - - -
DHGIOLOB_01200 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DHGIOLOB_01201 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
DHGIOLOB_01202 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DHGIOLOB_01203 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
DHGIOLOB_01204 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
DHGIOLOB_01205 4.39e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
DHGIOLOB_01206 3.39e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DHGIOLOB_01207 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
DHGIOLOB_01208 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DHGIOLOB_01209 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
DHGIOLOB_01210 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
DHGIOLOB_01211 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
DHGIOLOB_01212 3.65e-78 yloU - - S - - - protein conserved in bacteria
DHGIOLOB_01213 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
DHGIOLOB_01214 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
DHGIOLOB_01215 9.44e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
DHGIOLOB_01216 4.57e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DHGIOLOB_01217 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
DHGIOLOB_01218 2.05e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
DHGIOLOB_01219 3.07e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DHGIOLOB_01220 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DHGIOLOB_01221 1.05e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DHGIOLOB_01222 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DHGIOLOB_01223 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DHGIOLOB_01224 4.21e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DHGIOLOB_01225 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DHGIOLOB_01226 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
DHGIOLOB_01227 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
DHGIOLOB_01228 8.41e-202 yloC - - S - - - stress-induced protein
DHGIOLOB_01229 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
DHGIOLOB_01230 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
DHGIOLOB_01231 5.37e-107 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
DHGIOLOB_01232 2.5e-188 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
DHGIOLOB_01233 4.85e-184 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
DHGIOLOB_01234 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
DHGIOLOB_01235 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
DHGIOLOB_01236 1.41e-227 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
DHGIOLOB_01237 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
DHGIOLOB_01239 1.27e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DHGIOLOB_01240 2.67e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DHGIOLOB_01241 2.46e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DHGIOLOB_01242 4.31e-182 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
DHGIOLOB_01243 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
DHGIOLOB_01244 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
DHGIOLOB_01245 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DHGIOLOB_01246 2.97e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
DHGIOLOB_01247 2.24e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
DHGIOLOB_01248 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DHGIOLOB_01249 8.3e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
DHGIOLOB_01250 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DHGIOLOB_01251 2.63e-82 ylyA - - T - - - COG1734 DnaK suppressor protein
DHGIOLOB_01252 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DHGIOLOB_01253 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
DHGIOLOB_01254 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
DHGIOLOB_01255 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
DHGIOLOB_01256 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DHGIOLOB_01257 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DHGIOLOB_01258 3.73e-203 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
DHGIOLOB_01259 3.58e-51 ylmC - - S - - - sporulation protein
DHGIOLOB_01260 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
DHGIOLOB_01261 1.1e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
DHGIOLOB_01262 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DHGIOLOB_01263 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DHGIOLOB_01264 2.05e-218 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
DHGIOLOB_01265 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
DHGIOLOB_01266 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DHGIOLOB_01267 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DHGIOLOB_01268 5.37e-76 sbp - - S - - - small basic protein
DHGIOLOB_01269 1.5e-132 ylxX - - S - - - protein conserved in bacteria
DHGIOLOB_01270 1.35e-143 ylxW - - S - - - protein conserved in bacteria
DHGIOLOB_01271 3.37e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DHGIOLOB_01272 3.74e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
DHGIOLOB_01273 1.82e-255 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DHGIOLOB_01274 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
DHGIOLOB_01275 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DHGIOLOB_01276 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DHGIOLOB_01277 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DHGIOLOB_01278 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
DHGIOLOB_01279 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
DHGIOLOB_01280 3.42e-68 ftsL - - D - - - Essential cell division protein
DHGIOLOB_01281 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DHGIOLOB_01282 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
DHGIOLOB_01283 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DHGIOLOB_01284 5.34e-213 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DHGIOLOB_01285 1.33e-115 ylbP - - K - - - n-acetyltransferase
DHGIOLOB_01286 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
DHGIOLOB_01287 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
DHGIOLOB_01288 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
DHGIOLOB_01290 7.11e-293 ylbM - - S - - - Belongs to the UPF0348 family
DHGIOLOB_01291 2.24e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
DHGIOLOB_01292 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
DHGIOLOB_01293 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
DHGIOLOB_01294 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DHGIOLOB_01295 6.07e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
DHGIOLOB_01296 4.36e-52 ylbG - - S - - - UPF0298 protein
DHGIOLOB_01297 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
DHGIOLOB_01298 1.73e-48 ylbE - - S - - - YlbE-like protein
DHGIOLOB_01299 9.28e-89 ylbD - - S - - - Putative coat protein
DHGIOLOB_01300 4.39e-256 ylbC - - S - - - protein with SCP PR1 domains
DHGIOLOB_01301 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
DHGIOLOB_01302 1.61e-81 ylbA - - S - - - YugN-like family
DHGIOLOB_01303 1.21e-213 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
DHGIOLOB_01304 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
DHGIOLOB_01305 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
DHGIOLOB_01306 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DHGIOLOB_01307 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
DHGIOLOB_01308 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
DHGIOLOB_01309 2.85e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
DHGIOLOB_01310 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DHGIOLOB_01311 7.05e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
DHGIOLOB_01312 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
DHGIOLOB_01313 2.87e-218 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
DHGIOLOB_01314 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DHGIOLOB_01315 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
DHGIOLOB_01316 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DHGIOLOB_01317 8.92e-44 ylaI - - S - - - protein conserved in bacteria
DHGIOLOB_01318 4.4e-63 ylaH - - S - - - YlaH-like protein
DHGIOLOB_01319 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
DHGIOLOB_01320 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
DHGIOLOB_01321 1.74e-57 ylaE - - - - - - -
DHGIOLOB_01323 3.56e-115 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DHGIOLOB_01324 1.44e-56 ylaB - - - - - - -
DHGIOLOB_01325 0.0 ylaA - - - - - - -
DHGIOLOB_01326 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
DHGIOLOB_01327 7.08e-221 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DHGIOLOB_01328 2.45e-99 ykzC - - S - - - Acetyltransferase (GNAT) family
DHGIOLOB_01329 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
DHGIOLOB_01330 4.48e-35 ykzI - - - - - - -
DHGIOLOB_01331 1.25e-150 yktB - - S - - - Belongs to the UPF0637 family
DHGIOLOB_01332 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
DHGIOLOB_01333 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
DHGIOLOB_01334 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
DHGIOLOB_01335 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
DHGIOLOB_01336 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DHGIOLOB_01337 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DHGIOLOB_01338 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
DHGIOLOB_01339 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
DHGIOLOB_01340 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
DHGIOLOB_01341 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DHGIOLOB_01342 4.79e-186 ykrA - - S - - - hydrolases of the HAD superfamily
DHGIOLOB_01343 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
DHGIOLOB_01344 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DHGIOLOB_01345 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DHGIOLOB_01346 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
DHGIOLOB_01347 2.41e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
DHGIOLOB_01348 2.65e-306 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
DHGIOLOB_01349 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
DHGIOLOB_01350 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
DHGIOLOB_01351 6.35e-18 - - - S - - - Uncharacterized protein YkpC
DHGIOLOB_01352 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
DHGIOLOB_01353 7.87e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DHGIOLOB_01354 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
DHGIOLOB_01355 5.43e-52 ykoA - - - - - - -
DHGIOLOB_01356 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
DHGIOLOB_01357 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
DHGIOLOB_01358 4.07e-215 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
DHGIOLOB_01359 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_01360 1.11e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
DHGIOLOB_01361 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_01362 1.16e-233 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DHGIOLOB_01363 5.97e-147 yknW - - S - - - Yip1 domain
DHGIOLOB_01364 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
DHGIOLOB_01365 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
DHGIOLOB_01366 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DHGIOLOB_01367 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
DHGIOLOB_01368 1.99e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
DHGIOLOB_01369 4.29e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
DHGIOLOB_01370 2.54e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
DHGIOLOB_01371 2.17e-140 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
DHGIOLOB_01372 3.3e-198 yknT - - - ko:K06437 - ko00000 -
DHGIOLOB_01373 1.78e-120 rok - - K - - - Repressor of ComK
DHGIOLOB_01374 6.01e-104 ykuV - - CO - - - thiol-disulfide
DHGIOLOB_01375 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
DHGIOLOB_01376 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
DHGIOLOB_01377 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
DHGIOLOB_01378 1.27e-272 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DHGIOLOB_01379 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DHGIOLOB_01380 1.2e-100 fld - - C ko:K03839 - ko00000 Flavodoxin
DHGIOLOB_01381 1.18e-220 ykuO - - - - - - -
DHGIOLOB_01382 1.44e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
DHGIOLOB_01383 6.52e-216 ccpC - - K - - - Transcriptional regulator
DHGIOLOB_01384 5.15e-100 ykuL - - S - - - CBS domain
DHGIOLOB_01385 7.83e-38 ykzF - - S - - - Antirepressor AbbA
DHGIOLOB_01386 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
DHGIOLOB_01387 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
DHGIOLOB_01388 7.16e-298 ykuI - - T - - - Diguanylate phosphodiesterase
DHGIOLOB_01389 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DHGIOLOB_01390 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
DHGIOLOB_01391 5.84e-115 ykuD - - S - - - protein conserved in bacteria
DHGIOLOB_01392 3.62e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_01393 7.49e-110 ykyB - - S - - - YkyB-like protein
DHGIOLOB_01394 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
DHGIOLOB_01395 1.05e-22 - - - - - - - -
DHGIOLOB_01396 3.44e-282 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
DHGIOLOB_01397 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_01398 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
DHGIOLOB_01399 1.04e-169 ykwD - - J - - - protein with SCP PR1 domains
DHGIOLOB_01400 1.68e-17 vgb - - H ko:K18235 - ko00000,ko01000,ko01504 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
DHGIOLOB_01401 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
DHGIOLOB_01402 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
DHGIOLOB_01403 4.2e-160 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DHGIOLOB_01404 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
DHGIOLOB_01405 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_01406 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DHGIOLOB_01407 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
DHGIOLOB_01408 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DHGIOLOB_01409 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
DHGIOLOB_01411 5.43e-229 ykvZ - - K - - - Transcriptional regulator
DHGIOLOB_01413 1.93e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
DHGIOLOB_01414 3.99e-09 - - - - - - - -
DHGIOLOB_01415 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
DHGIOLOB_01416 5.79e-117 stoA - - CO - - - thiol-disulfide
DHGIOLOB_01417 9.18e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DHGIOLOB_01418 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
DHGIOLOB_01419 2.5e-39 - - - - - - - -
DHGIOLOB_01420 5.43e-35 ykvS - - S - - - protein conserved in bacteria
DHGIOLOB_01421 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
DHGIOLOB_01422 7.68e-172 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
DHGIOLOB_01423 2.8e-81 ykvN - - K - - - Transcriptional regulator
DHGIOLOB_01424 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DHGIOLOB_01425 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
DHGIOLOB_01426 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
DHGIOLOB_01427 6.42e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DHGIOLOB_01428 3.35e-227 ykvI - - S - - - membrane
DHGIOLOB_01429 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
DHGIOLOB_01430 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
DHGIOLOB_01431 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
DHGIOLOB_01432 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
DHGIOLOB_01433 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
DHGIOLOB_01434 5.84e-95 eag - - - - - - -
DHGIOLOB_01436 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
DHGIOLOB_01437 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DHGIOLOB_01438 4.34e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
DHGIOLOB_01439 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
DHGIOLOB_01440 9.72e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
DHGIOLOB_01441 1.96e-295 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
DHGIOLOB_01442 4.7e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
DHGIOLOB_01443 1.43e-292 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
DHGIOLOB_01444 3.8e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DHGIOLOB_01446 4.58e-114 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DHGIOLOB_01447 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_01448 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
DHGIOLOB_01449 1.77e-28 ykzE - - - - - - -
DHGIOLOB_01451 2.58e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
DHGIOLOB_01452 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
DHGIOLOB_01453 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
DHGIOLOB_01454 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
DHGIOLOB_01455 9.93e-200 rsgI - - S - - - Anti-sigma factor N-terminus
DHGIOLOB_01456 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DHGIOLOB_01457 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
DHGIOLOB_01458 1.71e-143 ykoX - - S - - - membrane-associated protein
DHGIOLOB_01459 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
DHGIOLOB_01460 5.94e-203 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DHGIOLOB_01461 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
DHGIOLOB_01462 3.17e-236 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
DHGIOLOB_01463 0.0 ykoS - - - - - - -
DHGIOLOB_01464 1.77e-197 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
DHGIOLOB_01465 2.38e-127 ykoP - - G - - - polysaccharide deacetylase
DHGIOLOB_01466 3.68e-275 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
DHGIOLOB_01467 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
DHGIOLOB_01468 2.51e-35 ykoL - - - - - - -
DHGIOLOB_01469 3.3e-25 - - - - - - - -
DHGIOLOB_01470 1.49e-70 tnrA - - K - - - transcriptional
DHGIOLOB_01471 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
DHGIOLOB_01473 1.45e-08 - - - - - - - -
DHGIOLOB_01474 5.28e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
DHGIOLOB_01475 9.6e-146 ykoI - - S - - - Peptidase propeptide and YPEB domain
DHGIOLOB_01476 1.42e-305 ykoH - - T - - - Histidine kinase
DHGIOLOB_01477 1.01e-157 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DHGIOLOB_01478 3.73e-137 ykoF - - S - - - YKOF-related Family
DHGIOLOB_01479 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
DHGIOLOB_01480 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_01481 7.36e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
DHGIOLOB_01482 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DHGIOLOB_01483 8.62e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
DHGIOLOB_01484 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DHGIOLOB_01485 1.9e-113 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
DHGIOLOB_01486 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
DHGIOLOB_01487 2.86e-97 ohrR - - K - - - COG1846 Transcriptional regulators
DHGIOLOB_01488 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
DHGIOLOB_01489 1.32e-288 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DHGIOLOB_01490 4.3e-255 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DHGIOLOB_01491 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
DHGIOLOB_01492 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
DHGIOLOB_01493 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
DHGIOLOB_01494 2.43e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DHGIOLOB_01495 6.42e-128 ykkA - - S - - - Protein of unknown function (DUF664)
DHGIOLOB_01496 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
DHGIOLOB_01497 2.11e-16 - - - - - - - -
DHGIOLOB_01498 1.26e-287 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DHGIOLOB_01499 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
DHGIOLOB_01500 1.78e-205 ykgA - - E - - - Amidinotransferase
DHGIOLOB_01501 3.16e-258 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
DHGIOLOB_01502 8.09e-235 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DHGIOLOB_01503 1.78e-210 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
DHGIOLOB_01504 1.55e-253 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
DHGIOLOB_01505 2.64e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
DHGIOLOB_01507 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
DHGIOLOB_01508 1.29e-234 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DHGIOLOB_01509 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DHGIOLOB_01510 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DHGIOLOB_01511 1.15e-195 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
DHGIOLOB_01512 3.2e-176 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
DHGIOLOB_01513 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DHGIOLOB_01515 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
DHGIOLOB_01516 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DHGIOLOB_01518 1.9e-231 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
DHGIOLOB_01519 2.57e-309 steT - - E ko:K03294 - ko00000 amino acid
DHGIOLOB_01520 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
DHGIOLOB_01521 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
DHGIOLOB_01522 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
DHGIOLOB_01523 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
DHGIOLOB_01524 5.76e-212 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
DHGIOLOB_01525 8.12e-53 xhlB - - S - - - SPP1 phage holin
DHGIOLOB_01526 7.71e-52 xhlA - - S - - - Haemolysin XhlA
DHGIOLOB_01527 6.16e-198 xepA - - - - - - -
DHGIOLOB_01528 1.1e-31 xkdX - - - - - - -
DHGIOLOB_01529 5.66e-70 xkdW - - S - - - XkdW protein
DHGIOLOB_01530 0.0 - - - - - - - -
DHGIOLOB_01531 4.43e-56 - - - - - - - -
DHGIOLOB_01532 6.51e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
DHGIOLOB_01533 1.26e-243 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
DHGIOLOB_01534 3.82e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
DHGIOLOB_01535 1.45e-51 xkdR - - S - - - Protein of unknown function (DUF2577)
DHGIOLOB_01536 2.31e-232 xkdQ - - G - - - NLP P60 protein
DHGIOLOB_01537 4.25e-152 xkdP - - S - - - Lysin motif
DHGIOLOB_01538 0.0 xkdO - - L - - - Transglycosylase SLT domain
DHGIOLOB_01539 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
DHGIOLOB_01540 6.01e-99 xkdM - - S - - - Phage tail tube protein
DHGIOLOB_01541 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
DHGIOLOB_01542 2.87e-101 xkdJ - - - - - - -
DHGIOLOB_01543 2.38e-114 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
DHGIOLOB_01544 2.91e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
DHGIOLOB_01545 6.64e-82 yqbG - - S - - - Protein of unknown function (DUF3199)
DHGIOLOB_01546 3.91e-217 xkdG - - S - - - Phage capsid family
DHGIOLOB_01547 1.4e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
DHGIOLOB_01548 0.0 yqbA - - S - - - portal protein
DHGIOLOB_01549 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
DHGIOLOB_01550 4.58e-177 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
DHGIOLOB_01551 8.12e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
DHGIOLOB_01556 7.48e-153 xkdC - - L - - - Bacterial dnaA protein
DHGIOLOB_01557 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
DHGIOLOB_01559 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
DHGIOLOB_01560 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
DHGIOLOB_01561 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
DHGIOLOB_01562 1.3e-137 yjqB - - S - - - Pfam:DUF867
DHGIOLOB_01563 1.35e-80 yjqA - - S - - - Bacterial PH domain
DHGIOLOB_01564 5.34e-218 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
DHGIOLOB_01565 1.79e-55 - - - S - - - YCII-related domain
DHGIOLOB_01567 7.06e-271 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
DHGIOLOB_01568 1.23e-313 VCP - - O - - - AAA domain (dynein-related subfamily)
DHGIOLOB_01569 2.71e-103 yjoA - - S - - - DinB family
DHGIOLOB_01570 1.31e-166 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
DHGIOLOB_01571 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
DHGIOLOB_01572 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
DHGIOLOB_01573 6.95e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
DHGIOLOB_01574 1.08e-286 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
DHGIOLOB_01575 2.23e-195 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGIOLOB_01576 1.08e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
DHGIOLOB_01577 1.86e-245 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
DHGIOLOB_01578 1.2e-240 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
DHGIOLOB_01579 1.19e-311 - - - G ko:K03292 - ko00000 symporter YjmB
DHGIOLOB_01580 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
DHGIOLOB_01581 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
DHGIOLOB_01582 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
DHGIOLOB_01583 2.36e-116 yjlB - - S - - - Cupin domain
DHGIOLOB_01584 8.95e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
DHGIOLOB_01585 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
DHGIOLOB_01586 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
DHGIOLOB_01587 8.69e-189 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
DHGIOLOB_01588 1.11e-41 - - - - - - - -
DHGIOLOB_01589 1.19e-277 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
DHGIOLOB_01590 1.16e-286 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
DHGIOLOB_01592 1.45e-144 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
DHGIOLOB_01594 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
DHGIOLOB_01595 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
DHGIOLOB_01596 5.79e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
DHGIOLOB_01597 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
DHGIOLOB_01598 1.36e-211 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
DHGIOLOB_01599 1.13e-29 yjfB - - S - - - Putative motility protein
DHGIOLOB_01600 8.68e-106 - - - S - - - Protein of unknown function (DUF2690)
DHGIOLOB_01601 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
DHGIOLOB_01603 5.08e-222 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
DHGIOLOB_01604 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
DHGIOLOB_01605 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
DHGIOLOB_01606 8.3e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DHGIOLOB_01608 1.47e-116 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
DHGIOLOB_01609 7.58e-75 yjdF3 - - S - - - Protein of unknown function (DUF2992)
DHGIOLOB_01610 3.58e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
DHGIOLOB_01611 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DHGIOLOB_01612 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
DHGIOLOB_01613 8.47e-59 yjcN - - - - - - -
DHGIOLOB_01614 2.59e-22 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
DHGIOLOB_01615 4.48e-23 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
DHGIOLOB_01616 2.49e-07 - - - - - - - -
DHGIOLOB_01617 2.28e-25 - - - - - - - -
DHGIOLOB_01618 1.92e-47 - - - - - - - -
DHGIOLOB_01622 2.51e-19 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_01624 6.79e-11 - - - S - - - Family of unknown function (DUF5316)
DHGIOLOB_01626 1.8e-87 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
DHGIOLOB_01627 2.27e-104 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
DHGIOLOB_01628 2.83e-198 - - - M - - - nucleic acid phosphodiester bond hydrolysis
DHGIOLOB_01629 4.49e-136 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
DHGIOLOB_01635 4.34e-94 - - - S - - - peptidoglycan catabolic process
DHGIOLOB_01637 9.06e-82 - - - - - - - -
DHGIOLOB_01639 2.3e-41 - - - - - - - -
DHGIOLOB_01640 2.53e-23 - - - - - - - -
DHGIOLOB_01645 2.21e-56 - - - - - - - -
DHGIOLOB_01646 1.6e-309 - - - I - - - Pfam Lipase (class 3)
DHGIOLOB_01647 2.11e-66 - - - S - - - Protein of unknown function (DUF1433)
DHGIOLOB_01648 3.64e-158 ynaC - - - - - - -
DHGIOLOB_01649 8.25e-61 - - - S - - - Restriction endonuclease
DHGIOLOB_01650 3.17e-32 - - - - - - - -
DHGIOLOB_01651 1.14e-20 - - - S - - - peptidoglycan catabolic process
DHGIOLOB_01652 5.35e-61 - - - K - - - Helix-turn-helix domain
DHGIOLOB_01653 8.18e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
DHGIOLOB_01654 3.71e-96 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
DHGIOLOB_01655 7.5e-80 - - - L ko:K07497 - ko00000 Integrase core domain
DHGIOLOB_01656 1.38e-66 - - - L - - - COG2963 Transposase and inactivated derivatives
DHGIOLOB_01657 4.17e-103 - - - - - - - -
DHGIOLOB_01658 3.77e-12 - - - S - - - Helix-turn-helix domain
DHGIOLOB_01659 4.52e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
DHGIOLOB_01660 6.49e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
DHGIOLOB_01663 1.05e-273 yjcL - - S - - - Protein of unknown function (DUF819)
DHGIOLOB_01664 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
DHGIOLOB_01665 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
DHGIOLOB_01666 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
DHGIOLOB_01667 1.91e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
DHGIOLOB_01668 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
DHGIOLOB_01669 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DHGIOLOB_01670 6.31e-51 - - - - - - - -
DHGIOLOB_01671 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
DHGIOLOB_01672 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
DHGIOLOB_01675 3.03e-76 yjcA - - S - - - Protein of unknown function (DUF1360)
DHGIOLOB_01676 1.44e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
DHGIOLOB_01677 1.08e-54 cotW - - - ko:K06341 - ko00000 -
DHGIOLOB_01678 3.55e-110 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
DHGIOLOB_01679 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
DHGIOLOB_01680 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
DHGIOLOB_01681 1.47e-103 yjbX - - S - - - Spore coat protein
DHGIOLOB_01682 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
DHGIOLOB_01683 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
DHGIOLOB_01684 1.52e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
DHGIOLOB_01685 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
DHGIOLOB_01686 5.35e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
DHGIOLOB_01687 1.33e-276 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
DHGIOLOB_01688 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
DHGIOLOB_01689 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DHGIOLOB_01690 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DHGIOLOB_01691 6.65e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
DHGIOLOB_01692 4.28e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
DHGIOLOB_01693 4.17e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DHGIOLOB_01694 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
DHGIOLOB_01695 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
DHGIOLOB_01696 7.32e-130 yjbK - - S - - - protein conserved in bacteria
DHGIOLOB_01697 4.85e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
DHGIOLOB_01698 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
DHGIOLOB_01699 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
DHGIOLOB_01700 2.68e-28 - - - - - - - -
DHGIOLOB_01701 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
DHGIOLOB_01702 4.7e-277 coiA - - S ko:K06198 - ko00000 Competence protein
DHGIOLOB_01703 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
DHGIOLOB_01704 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
DHGIOLOB_01705 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DHGIOLOB_01706 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DHGIOLOB_01707 3.35e-260 yjbB - - EGP - - - Major Facilitator Superfamily
DHGIOLOB_01708 1.27e-219 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DHGIOLOB_01709 1.12e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DHGIOLOB_01710 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DHGIOLOB_01711 4.89e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DHGIOLOB_01712 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
DHGIOLOB_01713 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
DHGIOLOB_01714 7.51e-189 yjbA - - S - - - Belongs to the UPF0736 family
DHGIOLOB_01715 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DHGIOLOB_01716 3.73e-213 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DHGIOLOB_01717 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
DHGIOLOB_01718 1.99e-235 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DHGIOLOB_01719 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
DHGIOLOB_01720 9.48e-193 yjaZ - - O - - - Zn-dependent protease
DHGIOLOB_01721 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DHGIOLOB_01722 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DHGIOLOB_01723 2.67e-38 yjzB - - - - - - -
DHGIOLOB_01724 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
DHGIOLOB_01725 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
DHGIOLOB_01726 5.41e-134 yjaV - - - - - - -
DHGIOLOB_01727 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
DHGIOLOB_01728 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
DHGIOLOB_01729 2.51e-39 yjzC - - S - - - YjzC-like protein
DHGIOLOB_01730 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DHGIOLOB_01731 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
DHGIOLOB_01732 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
DHGIOLOB_01733 1.69e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
DHGIOLOB_01734 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
DHGIOLOB_01735 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DHGIOLOB_01736 7.41e-255 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DHGIOLOB_01737 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
DHGIOLOB_01738 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
DHGIOLOB_01739 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
DHGIOLOB_01740 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
DHGIOLOB_01741 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
DHGIOLOB_01742 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
DHGIOLOB_01743 1.92e-08 - - - - - - - -
DHGIOLOB_01744 4.11e-25 - - - S - - - Protein of unknown function (DUF3813)
DHGIOLOB_01745 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
DHGIOLOB_01746 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
DHGIOLOB_01747 6.16e-200 yitS - - S - - - protein conserved in bacteria
DHGIOLOB_01748 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
DHGIOLOB_01749 5.37e-58 yitR - - S - - - Domain of unknown function (DUF3784)
DHGIOLOB_01750 5.02e-119 - - - - - - - -
DHGIOLOB_01751 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
DHGIOLOB_01752 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
DHGIOLOB_01753 4.76e-217 - - - - - - - -
DHGIOLOB_01754 4.16e-122 - - - - - - - -
DHGIOLOB_01755 2.75e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
DHGIOLOB_01756 4.29e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
DHGIOLOB_01757 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
DHGIOLOB_01758 8.44e-91 - - - S - - - Acetyltransferase (GNAT) domain
DHGIOLOB_01759 2.39e-192 yitH - - K - - - Acetyltransferase (GNAT) domain
DHGIOLOB_01760 8.28e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_01761 6.13e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
DHGIOLOB_01762 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
DHGIOLOB_01763 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
DHGIOLOB_01764 3.84e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
DHGIOLOB_01765 9.51e-185 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
DHGIOLOB_01766 1.37e-295 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
DHGIOLOB_01767 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
DHGIOLOB_01768 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DHGIOLOB_01769 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
DHGIOLOB_01770 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DHGIOLOB_01771 5.19e-138 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
DHGIOLOB_01772 1.72e-120 yisT - - S - - - DinB family
DHGIOLOB_01773 1.73e-247 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
DHGIOLOB_01774 3.04e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
DHGIOLOB_01775 1.41e-207 yisR - - K - - - Transcriptional regulator
DHGIOLOB_01776 2.91e-310 yisQ - - V - - - Mate efflux family protein
DHGIOLOB_01777 8.91e-189 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
DHGIOLOB_01778 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
DHGIOLOB_01779 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
DHGIOLOB_01780 2.49e-130 yisN - - S - - - Protein of unknown function (DUF2777)
DHGIOLOB_01781 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
DHGIOLOB_01782 1.02e-74 yisL - - S - - - UPF0344 protein
DHGIOLOB_01783 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
DHGIOLOB_01784 2.11e-219 cotH - - M ko:K06330 - ko00000 Spore Coat
DHGIOLOB_01785 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
DHGIOLOB_01786 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
DHGIOLOB_01787 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
DHGIOLOB_01788 3.34e-92 gerPC - - S ko:K06301 - ko00000 Spore germination protein
DHGIOLOB_01789 1.49e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
DHGIOLOB_01790 4.58e-85 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
DHGIOLOB_01791 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
DHGIOLOB_01792 1.84e-64 yisB - - V - - - COG1403 Restriction endonuclease
DHGIOLOB_01793 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
DHGIOLOB_01794 1.4e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DHGIOLOB_01795 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
DHGIOLOB_01796 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
DHGIOLOB_01797 3e-98 yhjR - - S - - - Rubrerythrin
DHGIOLOB_01798 3.54e-77 yhjQ - - C - - - COG1145 Ferredoxin
DHGIOLOB_01799 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
DHGIOLOB_01800 9.56e-268 - - - EGP - - - Transmembrane secretion effector
DHGIOLOB_01801 2.5e-259 yhjN - - S ko:K07120 - ko00000 membrane
DHGIOLOB_01802 2.07e-237 yhjM - - K - - - Transcriptional regulator
DHGIOLOB_01803 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
DHGIOLOB_01804 1.07e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
DHGIOLOB_01805 1.14e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
DHGIOLOB_01806 1.49e-270 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
DHGIOLOB_01809 4.01e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
DHGIOLOB_01810 0.0 yhjG - - CH - - - FAD binding domain
DHGIOLOB_01811 1.79e-117 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
DHGIOLOB_01812 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
DHGIOLOB_01813 4.13e-78 yhjD - - - - - - -
DHGIOLOB_01814 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
DHGIOLOB_01815 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DHGIOLOB_01816 2.04e-56 yhjA - - S - - - Excalibur calcium-binding domain
DHGIOLOB_01817 1.04e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
DHGIOLOB_01818 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
DHGIOLOB_01819 9.84e-45 yhzC - - S - - - IDEAL
DHGIOLOB_01820 2.24e-203 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DHGIOLOB_01821 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
DHGIOLOB_01822 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
DHGIOLOB_01823 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
DHGIOLOB_01824 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
DHGIOLOB_01825 1.39e-255 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
DHGIOLOB_01826 1.95e-140 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
DHGIOLOB_01827 1.53e-220 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
DHGIOLOB_01828 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
DHGIOLOB_01829 2.17e-102 - - - K - - - acetyltransferase
DHGIOLOB_01830 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
DHGIOLOB_01831 5.76e-301 yhfN - - O - - - Peptidase M48
DHGIOLOB_01832 2.78e-85 yhfM - - - - - - -
DHGIOLOB_01833 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
DHGIOLOB_01834 1.18e-140 yhfK - - GM - - - NmrA-like family
DHGIOLOB_01835 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
DHGIOLOB_01836 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
DHGIOLOB_01837 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DHGIOLOB_01838 1.53e-93 - - - S - - - ASCH
DHGIOLOB_01839 1.27e-251 yhfE - - G - - - peptidase M42
DHGIOLOB_01840 2.11e-174 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
DHGIOLOB_01841 1.77e-236 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DHGIOLOB_01842 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
DHGIOLOB_01843 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_01844 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DHGIOLOB_01845 4.65e-229 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
DHGIOLOB_01846 1.24e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DHGIOLOB_01847 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
DHGIOLOB_01848 1.53e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
DHGIOLOB_01849 5.85e-38 - - - C - - - Rubrerythrin
DHGIOLOB_01850 9.42e-313 yhfA - - C - - - membrane
DHGIOLOB_01851 6.27e-291 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
DHGIOLOB_01852 4.11e-161 ecsC - - S - - - EcsC protein family
DHGIOLOB_01853 1.27e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
DHGIOLOB_01854 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
DHGIOLOB_01855 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
DHGIOLOB_01856 1.24e-260 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DHGIOLOB_01857 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
DHGIOLOB_01858 1.74e-54 yhaH - - S - - - YtxH-like protein
DHGIOLOB_01859 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
DHGIOLOB_01860 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
DHGIOLOB_01861 3.3e-115 yhaK - - S - - - Putative zincin peptidase
DHGIOLOB_01862 2.33e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DHGIOLOB_01863 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
DHGIOLOB_01864 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
DHGIOLOB_01865 0.0 yhaN - - L - - - AAA domain
DHGIOLOB_01866 9.44e-301 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
DHGIOLOB_01867 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
DHGIOLOB_01868 3.22e-214 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_01869 2.29e-36 - - - S - - - YhzD-like protein
DHGIOLOB_01870 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
DHGIOLOB_01872 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
DHGIOLOB_01873 2.63e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
DHGIOLOB_01874 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
DHGIOLOB_01875 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
DHGIOLOB_01876 1.06e-260 yhaZ - - L - - - DNA alkylation repair enzyme
DHGIOLOB_01877 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
DHGIOLOB_01878 1.45e-259 yheB - - S - - - Belongs to the UPF0754 family
DHGIOLOB_01879 1.6e-274 yheC - - HJ - - - YheC/D like ATP-grasp
DHGIOLOB_01880 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
DHGIOLOB_01881 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
DHGIOLOB_01882 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
DHGIOLOB_01883 1.11e-141 yheG - - GM - - - NAD(P)H-binding
DHGIOLOB_01884 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
DHGIOLOB_01885 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
DHGIOLOB_01886 9.07e-108 nhaX - - T - - - Belongs to the universal stress protein A family
DHGIOLOB_01887 3.77e-305 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
DHGIOLOB_01888 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
DHGIOLOB_01889 1.18e-192 nodB1 - - G - - - deacetylase
DHGIOLOB_01890 2.7e-176 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
DHGIOLOB_01891 1.06e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
DHGIOLOB_01892 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
DHGIOLOB_01893 1.05e-171 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
DHGIOLOB_01894 1.38e-85 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DHGIOLOB_01895 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DHGIOLOB_01896 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
DHGIOLOB_01897 2.08e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
DHGIOLOB_01898 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
DHGIOLOB_01899 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
DHGIOLOB_01900 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
DHGIOLOB_01901 6.74e-244 yhdN - - C - - - Aldo keto reductase
DHGIOLOB_01902 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DHGIOLOB_01903 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
DHGIOLOB_01904 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
DHGIOLOB_01905 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DHGIOLOB_01906 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DHGIOLOB_01907 2.04e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
DHGIOLOB_01908 7.15e-316 yhdG - - E ko:K03294 - ko00000 amino acid
DHGIOLOB_01909 4.53e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DHGIOLOB_01910 7.18e-259 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
DHGIOLOB_01911 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_01912 1.45e-203 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
DHGIOLOB_01913 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
DHGIOLOB_01914 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
DHGIOLOB_01915 4.33e-306 ygxB - - M - - - Conserved TM helix
DHGIOLOB_01916 1.37e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
DHGIOLOB_01917 4.84e-275 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
DHGIOLOB_01918 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
DHGIOLOB_01919 1.65e-51 yhdB - - S - - - YhdB-like protein
DHGIOLOB_01920 1.1e-114 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
DHGIOLOB_01921 5.44e-144 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DHGIOLOB_01922 8.92e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_01923 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
DHGIOLOB_01924 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DHGIOLOB_01925 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DHGIOLOB_01926 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
DHGIOLOB_01927 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DHGIOLOB_01928 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DHGIOLOB_01929 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
DHGIOLOB_01930 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
DHGIOLOB_01931 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
DHGIOLOB_01932 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
DHGIOLOB_01933 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
DHGIOLOB_01934 5.1e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
DHGIOLOB_01935 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
DHGIOLOB_01936 2.39e-146 yhcQ - - M - - - Spore coat protein
DHGIOLOB_01937 5.17e-223 yhcP - - - - - - -
DHGIOLOB_01938 8.53e-104 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DHGIOLOB_01939 1.09e-61 yhcM - - - - - - -
DHGIOLOB_01940 3.22e-65 - - - K - - - Transcriptional regulator PadR-like family
DHGIOLOB_01941 9.8e-114 - - - S - - - Protein of unknown function (DUF2812)
DHGIOLOB_01942 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DHGIOLOB_01943 3.36e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
DHGIOLOB_01944 9.06e-194 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
DHGIOLOB_01945 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
DHGIOLOB_01946 1.99e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
DHGIOLOB_01947 3.59e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_01948 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_01949 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_01950 4.14e-69 - - - - - - - -
DHGIOLOB_01951 3.95e-59 yhcC - - - - - - -
DHGIOLOB_01952 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
DHGIOLOB_01953 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
DHGIOLOB_01954 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
DHGIOLOB_01955 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
DHGIOLOB_01956 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
DHGIOLOB_01957 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
DHGIOLOB_01958 4.28e-105 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
DHGIOLOB_01959 2.66e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
DHGIOLOB_01960 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
DHGIOLOB_01961 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DHGIOLOB_01962 2.77e-225 yhbB - - S - - - Putative amidase domain
DHGIOLOB_01963 1.2e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DHGIOLOB_01964 1.11e-146 yhzB - - S - - - B3/4 domain
DHGIOLOB_01966 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_01967 2.79e-102 ygaO - - - - - - -
DHGIOLOB_01968 3.97e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DHGIOLOB_01970 5.41e-275 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
DHGIOLOB_01971 4.82e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
DHGIOLOB_01972 4.88e-217 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
DHGIOLOB_01973 9.01e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
DHGIOLOB_01974 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
DHGIOLOB_01976 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DHGIOLOB_01977 3.56e-166 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
DHGIOLOB_01978 1.58e-36 - - - - - - - -
DHGIOLOB_01979 6.37e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
DHGIOLOB_01996 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
DHGIOLOB_01998 7.61e-203 ybaS - - S - - - Na -dependent transporter
DHGIOLOB_01999 7.15e-178 ybbA - - S ko:K07017 - ko00000 Putative esterase
DHGIOLOB_02000 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHGIOLOB_02001 1.17e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHGIOLOB_02002 2.54e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
DHGIOLOB_02003 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
DHGIOLOB_02004 8.49e-305 ybbC - - S - - - protein conserved in bacteria
DHGIOLOB_02005 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
DHGIOLOB_02006 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
DHGIOLOB_02007 2.09e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DHGIOLOB_02008 1.1e-193 ybbH - - K - - - transcriptional
DHGIOLOB_02009 4.52e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DHGIOLOB_02010 3.13e-114 ybbJ - - J - - - acetyltransferase
DHGIOLOB_02011 2.43e-100 ybbK - - S - - - Protein of unknown function (DUF523)
DHGIOLOB_02017 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DHGIOLOB_02018 1.3e-150 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
DHGIOLOB_02019 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DHGIOLOB_02020 8.33e-290 ybbR - - S - - - protein conserved in bacteria
DHGIOLOB_02021 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DHGIOLOB_02022 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DHGIOLOB_02023 3.67e-227 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DHGIOLOB_02024 6.9e-77 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
DHGIOLOB_02025 4.32e-126 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DHGIOLOB_02026 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
DHGIOLOB_02027 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
DHGIOLOB_02028 2.32e-119 ybcF - - P - - - carbonic anhydrase
DHGIOLOB_02030 1.6e-63 - - - - - - - -
DHGIOLOB_02031 7.26e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
DHGIOLOB_02032 3.85e-66 - - - K - - - Helix-turn-helix domain
DHGIOLOB_02033 6.59e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
DHGIOLOB_02034 9.98e-75 - - - - - - - -
DHGIOLOB_02036 1.14e-177 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
DHGIOLOB_02037 1.05e-192 ybdN - - - - - - -
DHGIOLOB_02038 4.76e-269 ybdO - - S - - - Domain of unknown function (DUF4885)
DHGIOLOB_02039 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
DHGIOLOB_02040 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
DHGIOLOB_02041 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
DHGIOLOB_02042 7.18e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
DHGIOLOB_02043 3.8e-314 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
DHGIOLOB_02044 1.3e-53 ybyB - - - - - - -
DHGIOLOB_02045 0.0 ybeC - - E - - - amino acid
DHGIOLOB_02046 1.36e-208 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
DHGIOLOB_02047 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
DHGIOLOB_02048 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
DHGIOLOB_02049 7.04e-217 ybfA - - K - - - FR47-like protein
DHGIOLOB_02050 2.63e-284 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_02053 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
DHGIOLOB_02054 3.56e-206 ybfH - - EG - - - EamA-like transporter family
DHGIOLOB_02055 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
DHGIOLOB_02056 1.27e-43 - - - K - - - sigma factor activity
DHGIOLOB_02057 2.73e-28 xhlB - - S - - - SPP1 phage holin
DHGIOLOB_02058 1.93e-122 - - GH19 M ko:K03791 - ko00000 Lysin motif
DHGIOLOB_02059 4.12e-73 - - - - - - - -
DHGIOLOB_02060 1.46e-267 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DHGIOLOB_02061 6.86e-228 mpr - - M - - - Belongs to the peptidase S1B family
DHGIOLOB_02063 5.56e-214 - - - S - - - Alpha/beta hydrolase family
DHGIOLOB_02064 2.81e-123 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DHGIOLOB_02065 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
DHGIOLOB_02066 2.06e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
DHGIOLOB_02067 1.58e-59 ybfN - - - - - - -
DHGIOLOB_02068 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
DHGIOLOB_02069 6.73e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
DHGIOLOB_02070 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DHGIOLOB_02071 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DHGIOLOB_02072 3.52e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DHGIOLOB_02073 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
DHGIOLOB_02075 3.44e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
DHGIOLOB_02076 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
DHGIOLOB_02077 8.72e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
DHGIOLOB_02078 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
DHGIOLOB_02079 5.08e-237 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
DHGIOLOB_02080 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_02081 9.96e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
DHGIOLOB_02082 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
DHGIOLOB_02083 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DHGIOLOB_02084 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_02085 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
DHGIOLOB_02086 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
DHGIOLOB_02087 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
DHGIOLOB_02088 1.74e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
DHGIOLOB_02089 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
DHGIOLOB_02090 9.95e-216 eamA1 - - EG - - - spore germination
DHGIOLOB_02091 2.61e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DHGIOLOB_02092 1.46e-212 ycbM - - T - - - Histidine kinase
DHGIOLOB_02093 1.52e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_02094 2.87e-148 - - - S - - - ABC-2 family transporter protein
DHGIOLOB_02095 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
DHGIOLOB_02096 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
DHGIOLOB_02097 4.66e-175 ycbR - - T - - - vWA found in TerF C terminus
DHGIOLOB_02098 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
DHGIOLOB_02099 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
DHGIOLOB_02100 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DHGIOLOB_02101 5.7e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DHGIOLOB_02102 2.16e-262 ycbU - - E - - - Selenocysteine lyase
DHGIOLOB_02103 1.24e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
DHGIOLOB_02104 1.54e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
DHGIOLOB_02105 1.69e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
DHGIOLOB_02106 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
DHGIOLOB_02107 8.72e-78 - - - S - - - RDD family
DHGIOLOB_02108 8.33e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
DHGIOLOB_02109 2.3e-208 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
DHGIOLOB_02110 5.64e-162 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
DHGIOLOB_02111 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
DHGIOLOB_02112 4.43e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
DHGIOLOB_02113 1.13e-220 yccK - - C - - - Aldo keto reductase
DHGIOLOB_02114 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
DHGIOLOB_02115 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DHGIOLOB_02116 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DHGIOLOB_02117 2.18e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
DHGIOLOB_02118 1.16e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
DHGIOLOB_02119 6.85e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
DHGIOLOB_02120 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
DHGIOLOB_02121 4.58e-220 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
DHGIOLOB_02122 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
DHGIOLOB_02123 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
DHGIOLOB_02124 6.65e-235 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DHGIOLOB_02125 3.75e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
DHGIOLOB_02126 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
DHGIOLOB_02127 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
DHGIOLOB_02128 4.1e-176 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
DHGIOLOB_02129 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
DHGIOLOB_02130 2.96e-245 yceH - - P - - - Belongs to the TelA family
DHGIOLOB_02131 1.9e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
DHGIOLOB_02132 1.42e-204 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
DHGIOLOB_02133 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
DHGIOLOB_02134 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
DHGIOLOB_02135 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
DHGIOLOB_02136 1.65e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
DHGIOLOB_02137 1.69e-277 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
DHGIOLOB_02138 0.0 ycgA - - S - - - Membrane
DHGIOLOB_02139 1.25e-127 ycgB - - - - - - -
DHGIOLOB_02140 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
DHGIOLOB_02141 1.19e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
DHGIOLOB_02142 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
DHGIOLOB_02143 0.0 mdr - - EGP - - - the major facilitator superfamily
DHGIOLOB_02144 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
DHGIOLOB_02145 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
DHGIOLOB_02146 1.85e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
DHGIOLOB_02147 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
DHGIOLOB_02148 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
DHGIOLOB_02149 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DHGIOLOB_02150 1.31e-140 tmrB - - S - - - AAA domain
DHGIOLOB_02151 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DHGIOLOB_02152 3.05e-185 - - - Q - - - ubiE/COQ5 methyltransferase family
DHGIOLOB_02153 5.4e-226 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
DHGIOLOB_02154 1.29e-230 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
DHGIOLOB_02155 4.49e-186 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
DHGIOLOB_02156 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
DHGIOLOB_02157 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
DHGIOLOB_02158 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DHGIOLOB_02159 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
DHGIOLOB_02160 3.14e-194 ycgQ - - S ko:K08986 - ko00000 membrane
DHGIOLOB_02161 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
DHGIOLOB_02162 1.46e-203 ycgS - - I - - - alpha/beta hydrolase fold
DHGIOLOB_02163 5.3e-239 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
DHGIOLOB_02164 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
DHGIOLOB_02165 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
DHGIOLOB_02166 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DHGIOLOB_02167 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DHGIOLOB_02168 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
DHGIOLOB_02169 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
DHGIOLOB_02170 2.76e-218 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
DHGIOLOB_02171 2.1e-140 - - - M - - - ErfK YbiS YcfS YnhG
DHGIOLOB_02172 6.78e-291 yciC - - S - - - GTPases (G3E family)
DHGIOLOB_02173 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
DHGIOLOB_02174 3.09e-186 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
DHGIOLOB_02176 1.38e-47 yckC - - S - - - membrane
DHGIOLOB_02177 4.82e-67 yckD - - S - - - Protein of unknown function (DUF2680)
DHGIOLOB_02178 7.43e-58 - - - K - - - MarR family
DHGIOLOB_02179 9e-32 - - - - - - - -
DHGIOLOB_02180 1.16e-154 - - - S - - - AAA domain
DHGIOLOB_02181 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
DHGIOLOB_02182 4.78e-91 nin - - S - - - Competence protein J (ComJ)
DHGIOLOB_02183 3.23e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
DHGIOLOB_02184 1.52e-267 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
DHGIOLOB_02185 1.54e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
DHGIOLOB_02186 8e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
DHGIOLOB_02187 6.05e-86 hxlR - - K - - - transcriptional
DHGIOLOB_02188 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHGIOLOB_02189 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHGIOLOB_02190 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
DHGIOLOB_02191 3.3e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
DHGIOLOB_02192 2.55e-287 - - - EGP - - - Major Facilitator Superfamily
DHGIOLOB_02193 2.99e-122 - - - S - - - YcxB-like protein
DHGIOLOB_02194 3.27e-205 ycxC - - EG - - - EamA-like transporter family
DHGIOLOB_02195 0.0 ycxD - - K - - - GntR family transcriptional regulator
DHGIOLOB_02196 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
DHGIOLOB_02197 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
DHGIOLOB_02198 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
DHGIOLOB_02199 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
DHGIOLOB_02200 3.03e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
DHGIOLOB_02201 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
DHGIOLOB_02202 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
DHGIOLOB_02203 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
DHGIOLOB_02204 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
DHGIOLOB_02205 2.32e-104 yclD - - - - - - -
DHGIOLOB_02206 5.5e-202 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
DHGIOLOB_02207 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
DHGIOLOB_02208 0.0 yclG - - M - - - Pectate lyase superfamily protein
DHGIOLOB_02210 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
DHGIOLOB_02211 1.97e-295 gerKC - - S ko:K06297 - ko00000 spore germination
DHGIOLOB_02212 1.33e-253 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
DHGIOLOB_02213 5.87e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
DHGIOLOB_02214 6.2e-277 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
DHGIOLOB_02215 4.5e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DHGIOLOB_02216 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
DHGIOLOB_02217 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
DHGIOLOB_02219 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
DHGIOLOB_02220 7.93e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
DHGIOLOB_02221 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
DHGIOLOB_02222 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHGIOLOB_02223 4.49e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHGIOLOB_02224 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_02225 5.72e-213 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
DHGIOLOB_02226 0.0 ycnB - - EGP - - - the major facilitator superfamily
DHGIOLOB_02227 2.91e-198 ycnC - - K - - - Transcriptional regulator
DHGIOLOB_02228 8.65e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
DHGIOLOB_02229 1.68e-60 ycnE - - S - - - Monooxygenase
DHGIOLOB_02230 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
DHGIOLOB_02231 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DHGIOLOB_02232 9.35e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DHGIOLOB_02233 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DHGIOLOB_02234 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
DHGIOLOB_02235 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DHGIOLOB_02236 8.06e-134 ycnI - - S - - - protein conserved in bacteria
DHGIOLOB_02237 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
DHGIOLOB_02238 4.98e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
DHGIOLOB_02239 9.44e-75 - - - - - - - -
DHGIOLOB_02240 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
DHGIOLOB_02241 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
DHGIOLOB_02242 1.21e-265 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
DHGIOLOB_02243 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
DHGIOLOB_02245 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
DHGIOLOB_02246 3.32e-141 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
DHGIOLOB_02247 1.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
DHGIOLOB_02249 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
DHGIOLOB_02250 3.14e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
DHGIOLOB_02251 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
DHGIOLOB_02252 2.01e-189 ycsI - - S - - - Belongs to the D-glutamate cyclase family
DHGIOLOB_02253 2.05e-172 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
DHGIOLOB_02254 1.91e-236 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
DHGIOLOB_02255 3.8e-171 kipR - - K - - - Transcriptional regulator
DHGIOLOB_02256 1.91e-150 ycsK - - E - - - anatomical structure formation involved in morphogenesis
DHGIOLOB_02258 8.97e-65 yczJ - - S - - - biosynthesis
DHGIOLOB_02259 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
DHGIOLOB_02260 2.57e-221 ycsN - - S - - - Oxidoreductase
DHGIOLOB_02261 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
DHGIOLOB_02262 0.0 ydaB - - IQ - - - acyl-CoA ligase
DHGIOLOB_02263 6.78e-126 ydaC - - Q - - - Methyltransferase domain
DHGIOLOB_02264 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DHGIOLOB_02265 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
DHGIOLOB_02266 2.58e-131 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DHGIOLOB_02267 5.24e-101 ydaG - - S - - - general stress protein
DHGIOLOB_02268 1.87e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
DHGIOLOB_02269 3.12e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
DHGIOLOB_02270 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
DHGIOLOB_02271 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DHGIOLOB_02272 1.03e-265 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
DHGIOLOB_02273 9.39e-195 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
DHGIOLOB_02274 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
DHGIOLOB_02275 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
DHGIOLOB_02276 1.73e-143 ydaN - - S - - - Bacterial cellulose synthase subunit
DHGIOLOB_02277 2.66e-310 ydaN - - S - - - Bacterial cellulose synthase subunit
DHGIOLOB_02278 0.0 ydaO - - E - - - amino acid
DHGIOLOB_02279 1.79e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
DHGIOLOB_02280 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
DHGIOLOB_02282 1.84e-34 - - - - - - - -
DHGIOLOB_02283 2.18e-90 sdpB - - S - - - Protein conserved in bacteria
DHGIOLOB_02285 2.14e-53 - - - - - - - -
DHGIOLOB_02286 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
DHGIOLOB_02287 1.67e-42 ydaS - - S - - - membrane
DHGIOLOB_02288 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
DHGIOLOB_02289 2.49e-189 ydbA - - P - - - EcsC protein family
DHGIOLOB_02290 3.3e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
DHGIOLOB_02291 1.25e-74 ydbB - - G - - - Cupin domain
DHGIOLOB_02292 3.53e-80 ydbC - - S - - - Domain of unknown function (DUF4937
DHGIOLOB_02293 2.24e-197 ydbD - - P ko:K07217 - ko00000 Catalase
DHGIOLOB_02294 3.66e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
DHGIOLOB_02295 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
DHGIOLOB_02296 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
DHGIOLOB_02297 1.27e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DHGIOLOB_02298 1.32e-230 ydbI - - S - - - AI-2E family transporter
DHGIOLOB_02299 2.66e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_02300 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
DHGIOLOB_02301 9.32e-70 ydbL - - - - - - -
DHGIOLOB_02302 1.5e-279 ydbM - - I - - - acyl-CoA dehydrogenase
DHGIOLOB_02303 1.49e-26 - - - S - - - Fur-regulated basic protein B
DHGIOLOB_02305 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DHGIOLOB_02306 4.19e-75 ydbP - - CO - - - Thioredoxin
DHGIOLOB_02307 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
DHGIOLOB_02308 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DHGIOLOB_02309 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DHGIOLOB_02310 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
DHGIOLOB_02311 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
DHGIOLOB_02312 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
DHGIOLOB_02313 1.95e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DHGIOLOB_02314 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
DHGIOLOB_02315 5.29e-284 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DHGIOLOB_02316 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
DHGIOLOB_02317 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
DHGIOLOB_02318 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
DHGIOLOB_02319 7.34e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
DHGIOLOB_02320 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
DHGIOLOB_02321 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
DHGIOLOB_02322 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
DHGIOLOB_02323 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
DHGIOLOB_02324 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DHGIOLOB_02325 4.38e-140 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
DHGIOLOB_02328 1.32e-106 ydcG - - S - - - EVE domain
DHGIOLOB_02329 1.04e-99 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
DHGIOLOB_02330 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
DHGIOLOB_02331 1.53e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
DHGIOLOB_02339 2.85e-266 ydcL - - L - - - Belongs to the 'phage' integrase family
DHGIOLOB_02340 7.82e-118 - - - E - - - Pfam:DUF955
DHGIOLOB_02341 9.07e-80 - - - K - - - Transcriptional
DHGIOLOB_02342 4.71e-47 - - - - - - - -
DHGIOLOB_02343 4.06e-48 - - - - - - - -
DHGIOLOB_02345 7.79e-85 - - - S - - - Bacterial protein of unknown function (DUF961)
DHGIOLOB_02346 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
DHGIOLOB_02347 2.93e-260 nicK - - L ko:K07467 - ko00000 Replication initiation factor
DHGIOLOB_02348 3.97e-49 - - - - - - - -
DHGIOLOB_02350 8.25e-63 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
DHGIOLOB_02351 2.33e-57 - - - - - - - -
DHGIOLOB_02352 1.05e-51 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
DHGIOLOB_02353 1.68e-82 - - - M - - - nucleic acid phosphodiester bond hydrolysis
DHGIOLOB_02355 4.75e-245 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
DHGIOLOB_02356 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
DHGIOLOB_02357 1.45e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
DHGIOLOB_02358 6.72e-41 ydzE - - EG - - - spore germination
DHGIOLOB_02359 1.08e-209 - - - K - - - AraC-like ligand binding domain
DHGIOLOB_02360 3.37e-222 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
DHGIOLOB_02361 9.2e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
DHGIOLOB_02362 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DHGIOLOB_02363 1.27e-275 ydeG - - EGP - - - Major facilitator superfamily
DHGIOLOB_02364 3.21e-70 ydeH - - - - - - -
DHGIOLOB_02365 5.52e-133 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
DHGIOLOB_02366 2.67e-144 - - - - - - - -
DHGIOLOB_02367 1.28e-194 ydeK - - EG - - - -transporter
DHGIOLOB_02368 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DHGIOLOB_02369 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
DHGIOLOB_02370 1.56e-131 - - - S ko:K07002 - ko00000 Serine hydrolase
DHGIOLOB_02371 1.02e-72 - - - K - - - HxlR-like helix-turn-helix
DHGIOLOB_02372 6.56e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
DHGIOLOB_02373 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
DHGIOLOB_02374 7.13e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DHGIOLOB_02375 5.44e-189 - - - J - - - GNAT acetyltransferase
DHGIOLOB_02376 1.45e-205 - - - EG - - - EamA-like transporter family
DHGIOLOB_02377 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DHGIOLOB_02378 1.54e-232 - 4.1.1.86 - E ko:K13745 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
DHGIOLOB_02379 4.04e-149 ydfE - - S - - - Flavin reductase like domain
DHGIOLOB_02380 1.23e-157 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
DHGIOLOB_02381 3.92e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DHGIOLOB_02382 2.77e-251 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_02383 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DHGIOLOB_02384 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
DHGIOLOB_02385 8.25e-218 - - - S - - - Alpha/beta hydrolase family
DHGIOLOB_02386 3.77e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
DHGIOLOB_02387 3.54e-188 - - - K - - - Bacterial transcription activator, effector binding domain
DHGIOLOB_02388 5.22e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DHGIOLOB_02389 4.7e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
DHGIOLOB_02390 1.11e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
DHGIOLOB_02391 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
DHGIOLOB_02392 3.78e-74 ydfQ - - CO - - - Thioredoxin
DHGIOLOB_02393 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
DHGIOLOB_02394 5.33e-39 - - - - - - - -
DHGIOLOB_02396 1.74e-152 ydfR - - S - - - Protein of unknown function (DUF421)
DHGIOLOB_02397 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
DHGIOLOB_02398 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
DHGIOLOB_02399 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
DHGIOLOB_02400 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
DHGIOLOB_02401 2.85e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
DHGIOLOB_02402 5.76e-70 - - - S - - - DoxX-like family
DHGIOLOB_02403 2.49e-114 yycN - - K - - - Acetyltransferase
DHGIOLOB_02404 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
DHGIOLOB_02405 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
DHGIOLOB_02406 1.2e-117 - - - S - - - DinB family
DHGIOLOB_02407 2.92e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
DHGIOLOB_02408 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
DHGIOLOB_02409 6.42e-147 ydgI - - C - - - nitroreductase
DHGIOLOB_02410 3.29e-90 - - - K - - - Winged helix DNA-binding domain
DHGIOLOB_02411 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
DHGIOLOB_02412 1.02e-154 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
DHGIOLOB_02413 4.31e-157 ydhC - - K - - - FCD
DHGIOLOB_02414 5.16e-309 ydhD - - M - - - Glycosyl hydrolase
DHGIOLOB_02415 3.91e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
DHGIOLOB_02416 1.43e-161 - - - - - - - -
DHGIOLOB_02417 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
DHGIOLOB_02418 2.74e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
DHGIOLOB_02420 7.65e-108 - - - K - - - Acetyltransferase (GNAT) domain
DHGIOLOB_02421 1.56e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
DHGIOLOB_02422 2.59e-126 ydhK - - M - - - Protein of unknown function (DUF1541)
DHGIOLOB_02423 2.56e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
DHGIOLOB_02424 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DHGIOLOB_02425 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DHGIOLOB_02426 3.76e-304 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DHGIOLOB_02427 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
DHGIOLOB_02428 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
DHGIOLOB_02429 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
DHGIOLOB_02430 3.44e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
DHGIOLOB_02431 2.64e-268 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
DHGIOLOB_02432 4.79e-100 ydhU - - P ko:K07217 - ko00000 Catalase
DHGIOLOB_02433 7.94e-22 ydhU - - P ko:K07217 - ko00000 Manganese containing catalase
DHGIOLOB_02436 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
DHGIOLOB_02437 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
DHGIOLOB_02438 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
DHGIOLOB_02439 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
DHGIOLOB_02440 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
DHGIOLOB_02441 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
DHGIOLOB_02442 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
DHGIOLOB_02443 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DHGIOLOB_02444 1.37e-99 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
DHGIOLOB_02445 3e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
DHGIOLOB_02446 2.37e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
DHGIOLOB_02447 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DHGIOLOB_02448 6.8e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
DHGIOLOB_02449 1.86e-212 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
DHGIOLOB_02450 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
DHGIOLOB_02451 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
DHGIOLOB_02452 2.78e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
DHGIOLOB_02453 7.27e-42 yqkK - - - - - - -
DHGIOLOB_02454 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
DHGIOLOB_02455 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
DHGIOLOB_02456 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
DHGIOLOB_02457 7.23e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
DHGIOLOB_02458 3.18e-77 ansR - - K - - - Transcriptional regulator
DHGIOLOB_02459 1.19e-279 yqxK - - L - - - DNA helicase
DHGIOLOB_02460 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
DHGIOLOB_02461 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
DHGIOLOB_02462 1.04e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
DHGIOLOB_02463 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
DHGIOLOB_02464 5.61e-221 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
DHGIOLOB_02465 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
DHGIOLOB_02466 1.25e-72 yqkB - - S - - - Belongs to the HesB IscA family
DHGIOLOB_02467 2.28e-248 yqkA - - K - - - GrpB protein
DHGIOLOB_02468 2.25e-78 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
DHGIOLOB_02469 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
DHGIOLOB_02470 3.23e-66 yqiX - - S - - - YolD-like protein
DHGIOLOB_02471 1.46e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DHGIOLOB_02473 7.96e-287 yqjV - - G - - - Major Facilitator Superfamily
DHGIOLOB_02475 5.43e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DHGIOLOB_02476 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
DHGIOLOB_02477 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
DHGIOLOB_02478 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGIOLOB_02479 5.2e-226 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
DHGIOLOB_02480 1.96e-189 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DHGIOLOB_02481 0.0 rocB - - E - - - arginine degradation protein
DHGIOLOB_02482 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
DHGIOLOB_02483 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DHGIOLOB_02484 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
DHGIOLOB_02485 2.2e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DHGIOLOB_02486 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DHGIOLOB_02487 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DHGIOLOB_02488 3.18e-300 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DHGIOLOB_02489 1.77e-32 yqzJ - - - - - - -
DHGIOLOB_02490 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DHGIOLOB_02491 5.7e-180 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
DHGIOLOB_02492 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
DHGIOLOB_02493 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
DHGIOLOB_02494 2.22e-93 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
DHGIOLOB_02496 9.84e-128 yqjB - - S - - - protein conserved in bacteria
DHGIOLOB_02497 3.49e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
DHGIOLOB_02498 1.49e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
DHGIOLOB_02499 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
DHGIOLOB_02500 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
DHGIOLOB_02501 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
DHGIOLOB_02502 1.21e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
DHGIOLOB_02503 1.79e-266 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_02504 3.03e-193 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
DHGIOLOB_02505 2.09e-285 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DHGIOLOB_02506 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DHGIOLOB_02507 1.11e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
DHGIOLOB_02508 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
DHGIOLOB_02509 1.96e-254 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
DHGIOLOB_02510 6.41e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
DHGIOLOB_02511 3.52e-198 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
DHGIOLOB_02512 0.0 bkdR - - KT - - - Transcriptional regulator
DHGIOLOB_02513 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
DHGIOLOB_02514 8.8e-209 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DHGIOLOB_02515 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
DHGIOLOB_02516 1.85e-264 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
DHGIOLOB_02517 2.86e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
DHGIOLOB_02518 6.9e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
DHGIOLOB_02519 1.83e-277 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
DHGIOLOB_02520 3.39e-168 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
DHGIOLOB_02521 9.4e-138 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
DHGIOLOB_02522 2.26e-37 - - - - - - - -
DHGIOLOB_02523 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
DHGIOLOB_02525 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
DHGIOLOB_02526 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
DHGIOLOB_02527 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
DHGIOLOB_02528 3.08e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
DHGIOLOB_02529 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
DHGIOLOB_02530 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DHGIOLOB_02531 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
DHGIOLOB_02532 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DHGIOLOB_02533 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DHGIOLOB_02534 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DHGIOLOB_02535 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DHGIOLOB_02536 9.55e-88 yqhY - - S - - - protein conserved in bacteria
DHGIOLOB_02537 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
DHGIOLOB_02538 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DHGIOLOB_02539 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
DHGIOLOB_02540 1.08e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
DHGIOLOB_02541 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
DHGIOLOB_02542 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
DHGIOLOB_02543 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
DHGIOLOB_02544 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
DHGIOLOB_02545 9.44e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
DHGIOLOB_02546 1.66e-216 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
DHGIOLOB_02547 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
DHGIOLOB_02548 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DHGIOLOB_02549 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
DHGIOLOB_02550 2.75e-100 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
DHGIOLOB_02551 9.37e-120 yqhR - - S - - - Conserved membrane protein YqhR
DHGIOLOB_02552 2.98e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
DHGIOLOB_02553 5.18e-81 yqhP - - - - - - -
DHGIOLOB_02554 4.93e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
DHGIOLOB_02555 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
DHGIOLOB_02556 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
DHGIOLOB_02557 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
DHGIOLOB_02558 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DHGIOLOB_02559 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DHGIOLOB_02560 7.79e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
DHGIOLOB_02561 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
DHGIOLOB_02562 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
DHGIOLOB_02563 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
DHGIOLOB_02564 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
DHGIOLOB_02565 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
DHGIOLOB_02566 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
DHGIOLOB_02567 4.43e-153 yqxM - - - ko:K19433 - ko00000 -
DHGIOLOB_02568 3.05e-69 yqzG - - S - - - Protein of unknown function (DUF3889)
DHGIOLOB_02569 4.9e-37 yqzE - - S - - - YqzE-like protein
DHGIOLOB_02570 1.08e-56 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
DHGIOLOB_02571 1.67e-45 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
DHGIOLOB_02572 7.23e-78 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
DHGIOLOB_02573 9.32e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
DHGIOLOB_02574 1.53e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
DHGIOLOB_02575 6.56e-214 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
DHGIOLOB_02576 2.13e-255 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DHGIOLOB_02577 2.13e-05 - - - T - - - CBS domain
DHGIOLOB_02578 7.17e-232 yqxL - - P - - - Mg2 transporter protein
DHGIOLOB_02579 1.36e-303 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
DHGIOLOB_02580 8.33e-191 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DHGIOLOB_02582 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
DHGIOLOB_02583 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
DHGIOLOB_02584 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
DHGIOLOB_02585 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
DHGIOLOB_02586 7.34e-66 yqgV - - S - - - Thiamine-binding protein
DHGIOLOB_02587 5.42e-256 yqgU - - - - - - -
DHGIOLOB_02588 4.14e-281 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
DHGIOLOB_02589 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
DHGIOLOB_02590 2.31e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
DHGIOLOB_02591 1.07e-43 yqgQ - - S - - - Protein conserved in bacteria
DHGIOLOB_02592 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
DHGIOLOB_02593 3.38e-14 yqgO - - - - - - -
DHGIOLOB_02594 4.27e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DHGIOLOB_02595 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
DHGIOLOB_02596 1.05e-252 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
DHGIOLOB_02598 3.42e-68 yqzD - - - - - - -
DHGIOLOB_02599 6.33e-93 yqzC - - S - - - YceG-like family
DHGIOLOB_02600 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DHGIOLOB_02601 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DHGIOLOB_02602 8.71e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
DHGIOLOB_02603 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
DHGIOLOB_02604 4.32e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
DHGIOLOB_02605 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
DHGIOLOB_02606 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
DHGIOLOB_02607 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
DHGIOLOB_02608 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
DHGIOLOB_02609 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
DHGIOLOB_02610 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
DHGIOLOB_02611 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DHGIOLOB_02612 2.04e-81 yqfX - - S - - - membrane
DHGIOLOB_02613 4.78e-141 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
DHGIOLOB_02614 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
DHGIOLOB_02615 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
DHGIOLOB_02616 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
DHGIOLOB_02617 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DHGIOLOB_02618 3.13e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DHGIOLOB_02619 3.36e-49 yqfQ - - S - - - YqfQ-like protein
DHGIOLOB_02620 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DHGIOLOB_02621 1.08e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DHGIOLOB_02622 1.1e-146 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
DHGIOLOB_02623 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
DHGIOLOB_02624 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DHGIOLOB_02625 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DHGIOLOB_02626 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
DHGIOLOB_02627 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DHGIOLOB_02628 3.29e-144 ccpN - - K - - - CBS domain
DHGIOLOB_02629 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
DHGIOLOB_02630 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
DHGIOLOB_02631 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
DHGIOLOB_02632 5.29e-27 - - - S - - - YqzL-like protein
DHGIOLOB_02633 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DHGIOLOB_02634 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
DHGIOLOB_02635 2.75e-79 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
DHGIOLOB_02636 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DHGIOLOB_02637 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
DHGIOLOB_02639 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
DHGIOLOB_02640 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
DHGIOLOB_02641 2.07e-60 yqfC - - S - - - sporulation protein YqfC
DHGIOLOB_02642 5.2e-78 yqfB - - - - - - -
DHGIOLOB_02643 4.35e-192 yqfA - - S - - - UPF0365 protein
DHGIOLOB_02644 5.14e-288 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
DHGIOLOB_02645 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
DHGIOLOB_02646 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
DHGIOLOB_02647 3.45e-202 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
DHGIOLOB_02648 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
DHGIOLOB_02649 1.01e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DHGIOLOB_02650 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
DHGIOLOB_02651 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DHGIOLOB_02652 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
DHGIOLOB_02653 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DHGIOLOB_02654 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DHGIOLOB_02655 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
DHGIOLOB_02656 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DHGIOLOB_02657 6.28e-73 yqxA - - S - - - Protein of unknown function (DUF3679)
DHGIOLOB_02658 9.53e-284 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
DHGIOLOB_02659 4.16e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DHGIOLOB_02660 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
DHGIOLOB_02661 9.55e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
DHGIOLOB_02662 2.36e-22 - - - S - - - YqzM-like protein
DHGIOLOB_02663 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
DHGIOLOB_02664 2.67e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
DHGIOLOB_02665 2.35e-127 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
DHGIOLOB_02666 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DHGIOLOB_02667 4.66e-177 yqeM - - Q - - - Methyltransferase
DHGIOLOB_02668 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DHGIOLOB_02669 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
DHGIOLOB_02670 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DHGIOLOB_02671 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
DHGIOLOB_02672 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DHGIOLOB_02673 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
DHGIOLOB_02674 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
DHGIOLOB_02676 1.84e-181 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
DHGIOLOB_02677 2.05e-177 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
DHGIOLOB_02678 8.6e-131 yqeD - - S - - - SNARE associated Golgi protein
DHGIOLOB_02679 8.54e-214 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
DHGIOLOB_02680 5.21e-168 - - - - - - - -
DHGIOLOB_02681 7.25e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
DHGIOLOB_02682 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DHGIOLOB_02683 0.0 - - - L ko:K06400 - ko00000 Recombinase
DHGIOLOB_02684 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
DHGIOLOB_02685 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
DHGIOLOB_02686 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DHGIOLOB_02687 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
DHGIOLOB_02688 1.7e-187 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
DHGIOLOB_02689 3.5e-119 - - - S - - - Tetratricopeptide repeat
DHGIOLOB_02692 1.13e-199 - - - S - - - Bacterial EndoU nuclease
DHGIOLOB_02693 8.71e-20 - - - S - - - SMI1 / KNR4 family
DHGIOLOB_02694 2.88e-61 - - - - - - - -
DHGIOLOB_02695 7.3e-131 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
DHGIOLOB_02697 5.4e-80 - - - - - - - -
DHGIOLOB_02699 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
DHGIOLOB_02700 1.19e-88 - - - S - - - Bacteriophage holin family
DHGIOLOB_02701 2.45e-213 xepA - - - - - - -
DHGIOLOB_02702 2.51e-28 - - - - - - - -
DHGIOLOB_02703 1.38e-71 xkdW - - S - - - XkdW protein
DHGIOLOB_02704 2.96e-246 - - - - - - - -
DHGIOLOB_02705 4.62e-49 - - - - - - - -
DHGIOLOB_02706 2.74e-126 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
DHGIOLOB_02707 6.67e-239 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
DHGIOLOB_02708 6.6e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
DHGIOLOB_02709 8.16e-42 xkdR - - S - - - Protein of unknown function (DUF2577)
DHGIOLOB_02710 8.96e-226 xkdQ - - G - - - NLP P60 protein
DHGIOLOB_02711 6.29e-154 xkdP - - S - - - Lysin motif
DHGIOLOB_02712 0.0 xkdO - - L - - - Transglycosylase SLT domain
DHGIOLOB_02713 1.12e-23 - - - - - - - -
DHGIOLOB_02714 1.27e-89 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
DHGIOLOB_02715 4.23e-99 xkdM - - S - - - Phage tail tube protein
DHGIOLOB_02716 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
DHGIOLOB_02717 1.21e-34 - - - - - - - -
DHGIOLOB_02718 1.48e-98 yqbJ - - - - - - -
DHGIOLOB_02719 8.84e-113 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
DHGIOLOB_02720 3.38e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
DHGIOLOB_02721 1.43e-87 - - - S - - - Protein of unknown function (DUF3199)
DHGIOLOB_02722 2.12e-60 - - - S - - - YqbF, hypothetical protein domain
DHGIOLOB_02723 7.57e-215 xkdG - - S - - - Phage capsid family
DHGIOLOB_02724 4.23e-158 yqbD - - L - - - Putative phage serine protease XkdF
DHGIOLOB_02725 5.03e-90 - - - S - - - Phage Mu protein F like protein
DHGIOLOB_02726 2.65e-196 - - - S - - - Phage Mu protein F like protein
DHGIOLOB_02727 0.0 yqbA - - S - - - portal protein
DHGIOLOB_02728 1.33e-312 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
DHGIOLOB_02729 5.28e-112 yqaS - - L - - - DNA packaging
DHGIOLOB_02730 1.19e-85 - - - S - - - Region found in RelA / SpoT proteins
DHGIOLOB_02735 1.25e-102 yqaQ - - L - - - Transposase
DHGIOLOB_02736 2.06e-61 - - - S - - - Beta protein
DHGIOLOB_02737 4.33e-70 - - - S - - - Psort location Cytoplasmic, score
DHGIOLOB_02738 2.4e-41 yqaO - - S - - - Phage-like element PBSX protein XtrA
DHGIOLOB_02739 9.37e-96 rusA - - L - - - Endodeoxyribonuclease RusA
DHGIOLOB_02741 3.55e-207 yqaM - - L - - - IstB-like ATP binding protein
DHGIOLOB_02742 5.29e-156 yqaL - - L - - - DnaD domain protein
DHGIOLOB_02743 2.79e-192 recT - - L ko:K07455 - ko00000,ko03400 RecT family
DHGIOLOB_02744 3.18e-213 yqaJ - - L - - - YqaJ-like viral recombinase domain
DHGIOLOB_02748 1.27e-134 - - - - - - - -
DHGIOLOB_02750 5.37e-25 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
DHGIOLOB_02751 1.88e-42 - - - K - - - sequence-specific DNA binding
DHGIOLOB_02753 6.63e-127 yqaC - - F - - - adenylate kinase activity
DHGIOLOB_02755 5.51e-123 xkdA - - E - - - IrrE N-terminal-like domain
DHGIOLOB_02756 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DHGIOLOB_02757 1.48e-81 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
DHGIOLOB_02758 4.05e-303 yrkQ - - T - - - Histidine kinase
DHGIOLOB_02759 7.15e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
DHGIOLOB_02760 7.21e-281 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
DHGIOLOB_02761 8.99e-133 yrkN - - K - - - Acetyltransferase (GNAT) family
DHGIOLOB_02762 4.7e-125 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
DHGIOLOB_02763 2.21e-102 - - - S - - - Protein of unknown function with HXXEE motif
DHGIOLOB_02764 6.63e-162 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
DHGIOLOB_02765 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
DHGIOLOB_02766 9.59e-269 yrkH - - P - - - Rhodanese Homology Domain
DHGIOLOB_02767 0.000112 perX - - S - - - DsrE/DsrF-like family
DHGIOLOB_02768 4.61e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
DHGIOLOB_02769 6.83e-109 yrkE - - O - - - DsrE/DsrF/DrsH-like family
DHGIOLOB_02770 4.38e-52 yrkD - - S - - - protein conserved in bacteria
DHGIOLOB_02771 3.32e-28 - - - - - - - -
DHGIOLOB_02772 1.28e-137 yrkC - - G - - - Cupin domain
DHGIOLOB_02773 4.42e-185 bltR - - K - - - helix_turn_helix, mercury resistance
DHGIOLOB_02774 2.17e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_02775 2.16e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
DHGIOLOB_02776 1.33e-293 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
DHGIOLOB_02777 2.45e-23 - - - S - - - YrzO-like protein
DHGIOLOB_02778 2.84e-215 yrdR - - EG - - - EamA-like transporter family
DHGIOLOB_02779 1.15e-202 - - - K - - - Transcriptional regulator
DHGIOLOB_02780 1.23e-253 trkA - - P ko:K07222 - ko00000 Oxidoreductase
DHGIOLOB_02781 1.88e-200 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
DHGIOLOB_02783 1.01e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
DHGIOLOB_02784 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
DHGIOLOB_02785 9.34e-176 azlC - - E - - - AzlC protein
DHGIOLOB_02786 4.13e-104 bkdR - - K - - - helix_turn_helix ASNC type
DHGIOLOB_02787 1.76e-22 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
DHGIOLOB_02788 1.08e-289 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
DHGIOLOB_02790 4.27e-130 yrdC - - Q - - - Isochorismatase family
DHGIOLOB_02791 1.04e-71 - - - S - - - Protein of unknown function (DUF2568)
DHGIOLOB_02792 2.01e-118 yrdA - - S - - - DinB family
DHGIOLOB_02793 8.54e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
DHGIOLOB_02794 4.23e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
DHGIOLOB_02795 1.56e-184 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
DHGIOLOB_02796 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
DHGIOLOB_02797 2.34e-128 - - - K ko:K05799 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
DHGIOLOB_02799 1.94e-266 - - - P - - - Major Facilitator Superfamily
DHGIOLOB_02800 1.7e-145 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DHGIOLOB_02801 6.83e-191 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
DHGIOLOB_02802 3.67e-174 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG3959 Transketolase, N-terminal subunit
DHGIOLOB_02804 7.88e-281 yfjF - - EGP - - - Belongs to the major facilitator superfamily
DHGIOLOB_02805 1.51e-85 napB - - K - - - MarR family transcriptional regulator
DHGIOLOB_02806 1.26e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
DHGIOLOB_02807 1.1e-124 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DHGIOLOB_02808 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
DHGIOLOB_02809 2.63e-286 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
DHGIOLOB_02810 2.97e-210 yraN - - K - - - Transcriptional regulator
DHGIOLOB_02811 5.95e-263 yraM - - S - - - PrpF protein
DHGIOLOB_02812 3.87e-200 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
DHGIOLOB_02813 1.45e-55 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DHGIOLOB_02814 6.66e-192 - - - S - - - Alpha beta hydrolase
DHGIOLOB_02815 7.73e-79 - - - T - - - sh3 domain protein
DHGIOLOB_02816 1.44e-79 - - - T - - - sh3 domain protein
DHGIOLOB_02817 3.15e-85 - - - E - - - Glyoxalase-like domain
DHGIOLOB_02818 4.19e-50 yraG - - - ko:K06440 - ko00000 -
DHGIOLOB_02819 9.61e-84 yraF - - M - - - Spore coat protein
DHGIOLOB_02820 4.84e-279 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
DHGIOLOB_02821 1.23e-35 yraE - - - ko:K06440 - ko00000 -
DHGIOLOB_02822 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
DHGIOLOB_02823 1.83e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
DHGIOLOB_02824 2.9e-10 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
DHGIOLOB_02825 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
DHGIOLOB_02826 2.25e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
DHGIOLOB_02827 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
DHGIOLOB_02828 3.27e-191 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
DHGIOLOB_02829 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
DHGIOLOB_02830 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
DHGIOLOB_02831 5.36e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
DHGIOLOB_02832 0.0 levR - - K - - - PTS system fructose IIA component
DHGIOLOB_02833 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
DHGIOLOB_02834 4.63e-136 yrhP - - E - - - LysE type translocator
DHGIOLOB_02835 5.9e-194 yrhO - - K - - - Archaeal transcriptional regulator TrmB
DHGIOLOB_02836 2.37e-185 rsiV - - S - - - Protein of unknown function (DUF3298)
DHGIOLOB_02837 0.0 oatA - - I - - - Acyltransferase family
DHGIOLOB_02838 6.32e-59 yrhK - - S - - - YrhK-like protein
DHGIOLOB_02839 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
DHGIOLOB_02840 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
DHGIOLOB_02841 8.67e-124 yrhH - - Q - - - methyltransferase
DHGIOLOB_02842 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
DHGIOLOB_02844 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
DHGIOLOB_02845 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
DHGIOLOB_02846 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
DHGIOLOB_02847 6.05e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
DHGIOLOB_02848 6.93e-49 yrhC - - S - - - YrhC-like protein
DHGIOLOB_02849 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
DHGIOLOB_02850 1.66e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
DHGIOLOB_02851 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DHGIOLOB_02852 3.44e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
DHGIOLOB_02853 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
DHGIOLOB_02854 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
DHGIOLOB_02855 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
DHGIOLOB_02856 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DHGIOLOB_02857 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
DHGIOLOB_02858 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
DHGIOLOB_02859 6.3e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
DHGIOLOB_02860 1.98e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
DHGIOLOB_02861 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DHGIOLOB_02862 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
DHGIOLOB_02863 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DHGIOLOB_02864 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
DHGIOLOB_02865 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DHGIOLOB_02866 1.25e-241 yrrI - - S - - - AI-2E family transporter
DHGIOLOB_02867 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
DHGIOLOB_02868 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
DHGIOLOB_02869 2.28e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DHGIOLOB_02870 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DHGIOLOB_02871 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
DHGIOLOB_02872 8.4e-42 yrzR - - - - - - -
DHGIOLOB_02873 1.44e-107 yrrD - - S - - - protein conserved in bacteria
DHGIOLOB_02874 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DHGIOLOB_02875 1.02e-38 yrrB - - S - - - COG0457 FOG TPR repeat
DHGIOLOB_02876 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DHGIOLOB_02877 2.98e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
DHGIOLOB_02878 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_02879 6.69e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
DHGIOLOB_02880 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
DHGIOLOB_02881 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DHGIOLOB_02882 7.06e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
DHGIOLOB_02884 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
DHGIOLOB_02885 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DHGIOLOB_02886 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DHGIOLOB_02887 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DHGIOLOB_02888 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
DHGIOLOB_02889 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
DHGIOLOB_02890 2.65e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
DHGIOLOB_02891 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DHGIOLOB_02892 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
DHGIOLOB_02893 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DHGIOLOB_02894 5.83e-143 yrbG - - S - - - membrane
DHGIOLOB_02895 1.46e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
DHGIOLOB_02896 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
DHGIOLOB_02897 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DHGIOLOB_02898 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DHGIOLOB_02899 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
DHGIOLOB_02900 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DHGIOLOB_02901 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DHGIOLOB_02902 1.85e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
DHGIOLOB_02903 0.0 csbX - - EGP - - - the major facilitator superfamily
DHGIOLOB_02904 4.59e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
DHGIOLOB_02905 1.91e-151 yrzF - - T - - - serine threonine protein kinase
DHGIOLOB_02907 6.26e-68 - - - S - - - Family of unknown function (DUF5412)
DHGIOLOB_02908 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
DHGIOLOB_02909 8.63e-165 yebC - - K - - - transcriptional regulatory protein
DHGIOLOB_02910 2.55e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
DHGIOLOB_02911 2.43e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
DHGIOLOB_02912 1.32e-271 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DHGIOLOB_02913 8.4e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
DHGIOLOB_02914 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
DHGIOLOB_02915 2.36e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
DHGIOLOB_02916 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
DHGIOLOB_02917 5.59e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DHGIOLOB_02918 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
DHGIOLOB_02919 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
DHGIOLOB_02920 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
DHGIOLOB_02921 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
DHGIOLOB_02922 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
DHGIOLOB_02923 1.23e-185 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
DHGIOLOB_02924 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
DHGIOLOB_02925 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
DHGIOLOB_02926 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
DHGIOLOB_02927 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
DHGIOLOB_02928 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
DHGIOLOB_02929 5.34e-66 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
DHGIOLOB_02930 2.51e-13 - - - - - - - -
DHGIOLOB_02932 1.66e-22 - - - K - - - Helix-turn-helix domain
DHGIOLOB_02934 1.88e-154 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
DHGIOLOB_02935 2.18e-75 - - - S - - - Bacteriophage holin family
DHGIOLOB_02938 7.33e-230 - - - S - - - Domain of unknown function (DUF2479)
DHGIOLOB_02939 0.0 - - - - - - - -
DHGIOLOB_02940 6.01e-134 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
DHGIOLOB_02942 0.0 - - - D - - - Phage tail tape measure protein
DHGIOLOB_02945 1.46e-33 - - - - - - - -
DHGIOLOB_02947 8.3e-40 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
DHGIOLOB_02948 8.17e-38 - - - S - - - Phage head-tail joining protein
DHGIOLOB_02950 2.16e-12 - - - - - - - -
DHGIOLOB_02951 7.58e-162 - - - S - - - capsid protein
DHGIOLOB_02952 1.32e-92 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
DHGIOLOB_02953 1.09e-215 - - - S - - - portal protein
DHGIOLOB_02955 0.0 terL - - S - - - Terminase
DHGIOLOB_02956 1.34e-77 - - - L - - - Terminase, small subunit
DHGIOLOB_02959 4.65e-60 - - - - - - - -
DHGIOLOB_02960 2.58e-65 - - - - - - - -
DHGIOLOB_02961 1.12e-289 - - - KL - - - SNF2 family N-terminal domain
DHGIOLOB_02962 3.23e-42 - - - S - - - VRR_NUC
DHGIOLOB_02963 0.0 - - - L - - - Virulence-associated protein E
DHGIOLOB_02966 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase A domain
DHGIOLOB_02967 1.07e-05 - - - - - - - -
DHGIOLOB_02968 1.57e-114 - - - S - - - Protein of unknown function (DUF2815)
DHGIOLOB_02969 3.86e-209 - - - L - - - Protein of unknown function (DUF2800)
DHGIOLOB_02970 1.04e-14 - - - - - - - -
DHGIOLOB_02971 1.01e-63 - - - - - - - -
DHGIOLOB_02974 6.56e-12 - - - K - - - helix-turn-helix
DHGIOLOB_02975 8.53e-84 - - - S - - - sequence-specific DNA binding
DHGIOLOB_02976 2.85e-93 - - - S - - - Pfam:Peptidase_M78
DHGIOLOB_02977 1.77e-291 - - - S - - - Recombinase
DHGIOLOB_02978 5.54e-86 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
DHGIOLOB_02979 1.66e-130 maf - - D ko:K06287 - ko00000 septum formation protein Maf
DHGIOLOB_02980 3.91e-207 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
DHGIOLOB_02981 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
DHGIOLOB_02982 1.83e-314 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
DHGIOLOB_02983 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DHGIOLOB_02984 1.53e-35 - - - - - - - -
DHGIOLOB_02985 2.79e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DHGIOLOB_02986 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
DHGIOLOB_02987 3.53e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
DHGIOLOB_02988 3.7e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
DHGIOLOB_02989 1.23e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
DHGIOLOB_02990 8.91e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
DHGIOLOB_02991 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
DHGIOLOB_02992 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DHGIOLOB_02993 4.77e-116 ysxD - - - - - - -
DHGIOLOB_02994 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
DHGIOLOB_02995 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DHGIOLOB_02996 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
DHGIOLOB_02997 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DHGIOLOB_02998 2.54e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DHGIOLOB_02999 3.19e-239 ysoA - - H - - - Tetratricopeptide repeat
DHGIOLOB_03000 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DHGIOLOB_03001 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DHGIOLOB_03002 8.67e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DHGIOLOB_03003 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DHGIOLOB_03004 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DHGIOLOB_03005 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
DHGIOLOB_03006 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
DHGIOLOB_03008 1.55e-44 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
DHGIOLOB_03009 6.77e-181 ysnF - - S - - - protein conserved in bacteria
DHGIOLOB_03011 1.65e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
DHGIOLOB_03012 7.86e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DHGIOLOB_03013 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DHGIOLOB_03014 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
DHGIOLOB_03015 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
DHGIOLOB_03016 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
DHGIOLOB_03017 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_03018 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
DHGIOLOB_03019 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
DHGIOLOB_03020 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
DHGIOLOB_03021 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
DHGIOLOB_03022 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
DHGIOLOB_03023 6.56e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
DHGIOLOB_03024 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DHGIOLOB_03025 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
DHGIOLOB_03026 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
DHGIOLOB_03027 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
DHGIOLOB_03028 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
DHGIOLOB_03029 1.81e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
DHGIOLOB_03030 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_03031 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
DHGIOLOB_03032 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
DHGIOLOB_03033 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DHGIOLOB_03034 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
DHGIOLOB_03035 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
DHGIOLOB_03036 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DHGIOLOB_03037 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DHGIOLOB_03038 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DHGIOLOB_03039 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DHGIOLOB_03040 1.81e-170 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DHGIOLOB_03041 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
DHGIOLOB_03042 1.45e-259 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
DHGIOLOB_03043 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
DHGIOLOB_03044 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
DHGIOLOB_03045 2.07e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
DHGIOLOB_03046 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
DHGIOLOB_03047 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
DHGIOLOB_03048 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
DHGIOLOB_03049 1.94e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
DHGIOLOB_03050 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
DHGIOLOB_03051 7.5e-282 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
DHGIOLOB_03052 1.67e-184 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
DHGIOLOB_03053 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
DHGIOLOB_03054 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
DHGIOLOB_03055 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
DHGIOLOB_03056 9.92e-242 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
DHGIOLOB_03057 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
DHGIOLOB_03058 3.26e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
DHGIOLOB_03059 3.65e-59 ysdA - - S - - - Membrane
DHGIOLOB_03060 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DHGIOLOB_03061 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
DHGIOLOB_03062 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DHGIOLOB_03064 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
DHGIOLOB_03065 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
DHGIOLOB_03066 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
DHGIOLOB_03067 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_03068 1.98e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
DHGIOLOB_03069 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DHGIOLOB_03071 3.46e-205 ytxC - - S - - - YtxC-like family
DHGIOLOB_03072 1.33e-141 ytxB - - S - - - SNARE associated Golgi protein
DHGIOLOB_03073 1e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
DHGIOLOB_03074 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
DHGIOLOB_03075 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DHGIOLOB_03076 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DHGIOLOB_03077 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DHGIOLOB_03078 1.15e-86 ytcD - - K - - - Transcriptional regulator
DHGIOLOB_03079 5.2e-258 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
DHGIOLOB_03080 4.54e-205 ytbE - - S - - - reductase
DHGIOLOB_03081 4e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DHGIOLOB_03082 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
DHGIOLOB_03083 4.05e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DHGIOLOB_03084 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DHGIOLOB_03085 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
DHGIOLOB_03086 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DHGIOLOB_03087 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
DHGIOLOB_03088 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
DHGIOLOB_03089 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
DHGIOLOB_03090 9.38e-95 ytwI - - S - - - membrane
DHGIOLOB_03091 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
DHGIOLOB_03092 3.16e-80 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
DHGIOLOB_03093 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
DHGIOLOB_03094 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DHGIOLOB_03095 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
DHGIOLOB_03096 8.83e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DHGIOLOB_03097 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
DHGIOLOB_03098 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
DHGIOLOB_03099 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
DHGIOLOB_03100 5.12e-112 ytrI - - - - - - -
DHGIOLOB_03101 1.15e-39 - - - - - - - -
DHGIOLOB_03102 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
DHGIOLOB_03103 2.15e-63 ytpI - - S - - - YtpI-like protein
DHGIOLOB_03104 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
DHGIOLOB_03105 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
DHGIOLOB_03106 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DHGIOLOB_03108 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
DHGIOLOB_03109 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
DHGIOLOB_03110 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
DHGIOLOB_03111 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DHGIOLOB_03112 1.08e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
DHGIOLOB_03113 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DHGIOLOB_03114 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
DHGIOLOB_03115 8.34e-149 ytfI - - S - - - Protein of unknown function (DUF2953)
DHGIOLOB_03116 1.37e-110 yteJ - - S - - - RDD family
DHGIOLOB_03117 9.73e-230 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
DHGIOLOB_03118 8.38e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DHGIOLOB_03119 0.0 ytcJ - - S - - - amidohydrolase
DHGIOLOB_03120 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
DHGIOLOB_03121 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
DHGIOLOB_03122 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DHGIOLOB_03123 1.3e-264 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
DHGIOLOB_03124 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
DHGIOLOB_03125 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DHGIOLOB_03126 5.29e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
DHGIOLOB_03127 4.87e-141 yttP - - K - - - Transcriptional regulator
DHGIOLOB_03128 3.24e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
DHGIOLOB_03129 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
DHGIOLOB_03130 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DHGIOLOB_03131 2.47e-08 - - - - - - - -
DHGIOLOB_03135 1.94e-137 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
DHGIOLOB_03136 4.91e-235 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
DHGIOLOB_03137 1.47e-85 - - - S - - - Immunity protein 70
DHGIOLOB_03138 1.13e-144 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
DHGIOLOB_03139 1.54e-75 - - - S - - - Bacteriophage holin family
DHGIOLOB_03142 1.93e-246 - - - S - - - Domain of unknown function (DUF2479)
DHGIOLOB_03143 0.0 - - - - - - - -
DHGIOLOB_03144 2.88e-277 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
DHGIOLOB_03145 1.19e-135 - - - S - - - Phage tail protein
DHGIOLOB_03146 0.0 - - - D - - - phage tail tape measure protein
DHGIOLOB_03149 2.65e-100 - - - S - - - Phage tail tube protein
DHGIOLOB_03151 1.19e-66 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
DHGIOLOB_03152 2.13e-51 - - - S - - - Phage head-tail joining protein
DHGIOLOB_03153 1.4e-50 - - - S - - - Phage gp6-like head-tail connector protein
DHGIOLOB_03154 1.89e-34 - - - - - - - -
DHGIOLOB_03155 1.06e-266 - - - S - - - capsid protein
DHGIOLOB_03156 6.14e-151 - - - OU - - - Belongs to the peptidase S14 family
DHGIOLOB_03157 2.64e-303 - - - S - - - Phage portal protein
DHGIOLOB_03159 0.0 - - - S - - - Terminase
DHGIOLOB_03160 6.85e-103 - - - L - - - phage terminase small subunit
DHGIOLOB_03161 6.88e-66 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
DHGIOLOB_03163 5.07e-14 - - - - - - - -
DHGIOLOB_03171 4.9e-66 - - - M - - - ArpU family transcriptional regulator
DHGIOLOB_03172 3.01e-12 - - - S - - - Phage-like element PBSX protein XtrA
DHGIOLOB_03173 7.58e-31 - - - - - - - -
DHGIOLOB_03174 3.8e-211 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 replicative DNA helicase
DHGIOLOB_03175 9.77e-18 - - - S - - - Loader and inhibitor of phage G40P
DHGIOLOB_03176 2.7e-128 - - - L - - - DnaD domain protein
DHGIOLOB_03179 1.42e-101 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
DHGIOLOB_03180 3.31e-26 - - - - - - - -
DHGIOLOB_03183 7.96e-41 - - - - - - - -
DHGIOLOB_03185 1.05e-18 yvaO - - K ko:K22299 - ko00000,ko03000 sequence-specific DNA binding
DHGIOLOB_03186 9.97e-59 - - - E - - - IrrE N-terminal-like domain
DHGIOLOB_03187 3.83e-202 - - - L - - - Belongs to the 'phage' integrase family
DHGIOLOB_03189 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DHGIOLOB_03190 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
DHGIOLOB_03191 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
DHGIOLOB_03192 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
DHGIOLOB_03193 1.81e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
DHGIOLOB_03194 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
DHGIOLOB_03195 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
DHGIOLOB_03196 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
DHGIOLOB_03197 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
DHGIOLOB_03198 2.23e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
DHGIOLOB_03199 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
DHGIOLOB_03200 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DHGIOLOB_03201 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
DHGIOLOB_03202 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
DHGIOLOB_03203 1.03e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DHGIOLOB_03204 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
DHGIOLOB_03205 3.17e-75 ytpP - - CO - - - Thioredoxin
DHGIOLOB_03206 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
DHGIOLOB_03207 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
DHGIOLOB_03208 3.34e-67 ytzB - - S - - - small secreted protein
DHGIOLOB_03209 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
DHGIOLOB_03210 1.3e-191 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
DHGIOLOB_03211 8.79e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DHGIOLOB_03212 9.51e-61 ytzH - - S - - - YtzH-like protein
DHGIOLOB_03213 3.02e-192 ytmP - - M - - - Phosphotransferase
DHGIOLOB_03214 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
DHGIOLOB_03215 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
DHGIOLOB_03216 8.15e-211 ytlQ - - - - - - -
DHGIOLOB_03217 2.04e-128 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DHGIOLOB_03218 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
DHGIOLOB_03219 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
DHGIOLOB_03220 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
DHGIOLOB_03221 4.99e-255 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
DHGIOLOB_03222 2.8e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
DHGIOLOB_03223 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
DHGIOLOB_03224 1.75e-168 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
DHGIOLOB_03225 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DHGIOLOB_03226 5.74e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
DHGIOLOB_03227 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
DHGIOLOB_03228 2.14e-36 yteV - - S - - - Sporulation protein Cse60
DHGIOLOB_03229 3.13e-149 yteU - - S - - - Integral membrane protein
DHGIOLOB_03230 1.2e-314 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
DHGIOLOB_03231 6.78e-94 yteS - - G - - - transport
DHGIOLOB_03232 1.18e-278 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
DHGIOLOB_03233 1.31e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
DHGIOLOB_03234 0.0 ytdP - - K - - - Transcriptional regulator
DHGIOLOB_03235 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
DHGIOLOB_03236 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
DHGIOLOB_03237 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
DHGIOLOB_03238 3.75e-287 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
DHGIOLOB_03239 1.46e-240 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DHGIOLOB_03240 2.68e-159 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DHGIOLOB_03241 2.58e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
DHGIOLOB_03242 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
DHGIOLOB_03243 7.51e-178 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
DHGIOLOB_03244 2.66e-218 - - - S - - - Acetyl xylan esterase (AXE1)
DHGIOLOB_03245 1.31e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_03246 8.99e-313 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
DHGIOLOB_03247 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
DHGIOLOB_03248 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
DHGIOLOB_03249 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
DHGIOLOB_03250 4.98e-68 ytwF - - P - - - Sulfurtransferase
DHGIOLOB_03251 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
DHGIOLOB_03252 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
DHGIOLOB_03253 1.56e-182 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
DHGIOLOB_03254 2.45e-268 yttB - - EGP - - - Major facilitator superfamily
DHGIOLOB_03255 2.67e-76 yttA - - S - - - Pfam Transposase IS66
DHGIOLOB_03256 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
DHGIOLOB_03257 1.56e-178 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_03258 6.9e-234 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
DHGIOLOB_03259 1.7e-165 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DHGIOLOB_03260 1.39e-296 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
DHGIOLOB_03261 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_03262 4.77e-193 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
DHGIOLOB_03263 1.98e-214 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
DHGIOLOB_03264 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_03265 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
DHGIOLOB_03267 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
DHGIOLOB_03268 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
DHGIOLOB_03269 1.17e-133 ytqB - - J - - - Putative rRNA methylase
DHGIOLOB_03270 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
DHGIOLOB_03271 4.7e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
DHGIOLOB_03272 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DHGIOLOB_03273 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
DHGIOLOB_03274 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
DHGIOLOB_03275 1.86e-285 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DHGIOLOB_03276 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DHGIOLOB_03277 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
DHGIOLOB_03278 5.48e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
DHGIOLOB_03279 1.87e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
DHGIOLOB_03280 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
DHGIOLOB_03281 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
DHGIOLOB_03282 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
DHGIOLOB_03283 3.2e-81 ytkC - - S - - - Bacteriophage holin family
DHGIOLOB_03284 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
DHGIOLOB_03286 4.78e-95 ytkA - - S - - - YtkA-like
DHGIOLOB_03287 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DHGIOLOB_03288 1.27e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
DHGIOLOB_03289 1.44e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
DHGIOLOB_03290 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
DHGIOLOB_03291 1.15e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
DHGIOLOB_03292 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
DHGIOLOB_03293 9.24e-192 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
DHGIOLOB_03294 4.31e-295 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
DHGIOLOB_03295 1.97e-175 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
DHGIOLOB_03296 1.79e-215 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
DHGIOLOB_03297 5.81e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
DHGIOLOB_03298 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
DHGIOLOB_03299 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DHGIOLOB_03300 6.65e-195 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
DHGIOLOB_03301 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DHGIOLOB_03302 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
DHGIOLOB_03303 3.53e-168 yteA - - T - - - COG1734 DnaK suppressor protein
DHGIOLOB_03304 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
DHGIOLOB_03305 7.94e-308 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DHGIOLOB_03306 5.23e-229 ytcB - - M - - - NAD-dependent epimerase dehydratase
DHGIOLOB_03307 6.86e-296 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
DHGIOLOB_03309 2.82e-262 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
DHGIOLOB_03310 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
DHGIOLOB_03311 2.59e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
DHGIOLOB_03312 8.04e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
DHGIOLOB_03313 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DHGIOLOB_03314 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
DHGIOLOB_03315 3.72e-238 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
DHGIOLOB_03316 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DHGIOLOB_03317 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DHGIOLOB_03334 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
DHGIOLOB_03335 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
DHGIOLOB_03336 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DHGIOLOB_03337 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
DHGIOLOB_03338 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DHGIOLOB_03339 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
DHGIOLOB_03340 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
DHGIOLOB_03341 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DHGIOLOB_03342 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DHGIOLOB_03344 1.93e-53 - - - - - - - -
DHGIOLOB_03345 7.05e-293 - - - S - - - Bacterial EndoU nuclease
DHGIOLOB_03348 4.31e-82 yozB - - S ko:K08976 - ko00000 Membrane
DHGIOLOB_03349 1.19e-30 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
DHGIOLOB_03350 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
DHGIOLOB_03351 1.51e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
DHGIOLOB_03352 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
DHGIOLOB_03353 1.73e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
DHGIOLOB_03354 3.1e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
DHGIOLOB_03355 4.25e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DHGIOLOB_03356 8.23e-170 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
DHGIOLOB_03357 4.21e-202 ydjI - - S - - - virion core protein (lumpy skin disease virus)
DHGIOLOB_03358 5.58e-248 - - - S - - - Ion transport 2 domain protein
DHGIOLOB_03359 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DHGIOLOB_03360 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
DHGIOLOB_03361 1.79e-84 ydjM - - M - - - Lytic transglycolase
DHGIOLOB_03362 2.81e-208 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
DHGIOLOB_03364 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
DHGIOLOB_03365 3.21e-205 - - - I - - - Alpha/beta hydrolase family
DHGIOLOB_03366 7.12e-229 yeaA - - S - - - Protein of unknown function (DUF4003)
DHGIOLOB_03367 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
DHGIOLOB_03368 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
DHGIOLOB_03369 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DHGIOLOB_03370 3.25e-225 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
DHGIOLOB_03371 5.31e-284 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
DHGIOLOB_03372 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
DHGIOLOB_03373 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
DHGIOLOB_03374 3.8e-112 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DHGIOLOB_03375 3.66e-311 - - - S - - - Domain of unknown function (DUF4179)
DHGIOLOB_03376 4.86e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
DHGIOLOB_03377 5.85e-165 yebC - - M - - - Membrane
DHGIOLOB_03379 2.66e-120 yebE - - S - - - UPF0316 protein
DHGIOLOB_03380 3.13e-38 yebG - - S - - - NETI protein
DHGIOLOB_03381 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DHGIOLOB_03382 7.39e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DHGIOLOB_03383 8.03e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DHGIOLOB_03384 1.18e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
DHGIOLOB_03385 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DHGIOLOB_03386 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DHGIOLOB_03387 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DHGIOLOB_03388 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DHGIOLOB_03389 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
DHGIOLOB_03390 7.3e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DHGIOLOB_03391 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
DHGIOLOB_03392 1.63e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
DHGIOLOB_03393 1.06e-95 - - - K - - - helix_turn_helix ASNC type
DHGIOLOB_03394 1.67e-291 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
DHGIOLOB_03395 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
DHGIOLOB_03396 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
DHGIOLOB_03397 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
DHGIOLOB_03398 7.62e-68 yerC - - S - - - protein conserved in bacteria
DHGIOLOB_03399 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
DHGIOLOB_03401 9.04e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DHGIOLOB_03402 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
DHGIOLOB_03403 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DHGIOLOB_03404 3.57e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
DHGIOLOB_03405 2.99e-251 yerI - - S - - - homoserine kinase type II (protein kinase fold)
DHGIOLOB_03406 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
DHGIOLOB_03407 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DHGIOLOB_03408 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DHGIOLOB_03410 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DHGIOLOB_03411 4.91e-189 yerO - - K - - - Transcriptional regulator
DHGIOLOB_03412 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DHGIOLOB_03413 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
DHGIOLOB_03414 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DHGIOLOB_03415 8.51e-06 - - - - - - - -
DHGIOLOB_03416 2.52e-102 - - - S - - - Protein of unknown function, DUF600
DHGIOLOB_03417 2.39e-68 - - - S - - - Protein of unknown function, DUF600
DHGIOLOB_03418 2.48e-66 - - - S - - - Protein of unknown function, DUF600
DHGIOLOB_03419 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
DHGIOLOB_03421 8.06e-126 - - - L - - - endonuclease activity
DHGIOLOB_03422 4.98e-15 - - - S - - - Lysozyme inhibitor LprI
DHGIOLOB_03423 2.57e-273 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
DHGIOLOB_03425 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
DHGIOLOB_03427 2.44e-130 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_03428 4.95e-107 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
DHGIOLOB_03429 5.83e-194 yesF - - GM - - - NAD(P)H-binding
DHGIOLOB_03430 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
DHGIOLOB_03431 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
DHGIOLOB_03432 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
DHGIOLOB_03433 9.78e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
DHGIOLOB_03435 1.95e-132 yesL - - S - - - Protein of unknown function, DUF624
DHGIOLOB_03436 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_03437 2.93e-259 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
DHGIOLOB_03438 4.13e-314 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
DHGIOLOB_03439 4.76e-217 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
DHGIOLOB_03440 5.33e-212 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
DHGIOLOB_03441 3.26e-253 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
DHGIOLOB_03442 0.0 yesS - - K - - - Transcriptional regulator
DHGIOLOB_03443 1.19e-169 - - - E - - - GDSL-like Lipase/Acylhydrolase
DHGIOLOB_03444 1.25e-163 yesU - - S - - - Domain of unknown function (DUF1961)
DHGIOLOB_03445 4.02e-145 - - - S - - - Protein of unknown function, DUF624
DHGIOLOB_03446 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
DHGIOLOB_03447 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
DHGIOLOB_03449 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
DHGIOLOB_03450 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
DHGIOLOB_03451 0.0 yetA - - - - - - -
DHGIOLOB_03452 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
DHGIOLOB_03453 2.78e-225 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
DHGIOLOB_03454 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
DHGIOLOB_03455 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
DHGIOLOB_03456 1.81e-157 yetF - - S - - - membrane
DHGIOLOB_03457 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
DHGIOLOB_03458 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DHGIOLOB_03459 1.75e-44 - - - - - - - -
DHGIOLOB_03460 7.23e-184 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DHGIOLOB_03461 4.46e-27 yezD - - S - - - Uncharacterized small protein (DUF2292)
DHGIOLOB_03462 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
DHGIOLOB_03463 1.42e-200 - - - EG - - - EamA-like transporter family
DHGIOLOB_03464 1.86e-114 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
DHGIOLOB_03465 2.43e-263 yetM - - CH - - - FAD binding domain
DHGIOLOB_03466 2.55e-65 - - - - - - - -
DHGIOLOB_03467 7.06e-251 yetN - - S - - - Protein of unknown function (DUF3900)
DHGIOLOB_03468 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
DHGIOLOB_03469 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
DHGIOLOB_03470 9.83e-187 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
DHGIOLOB_03471 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
DHGIOLOB_03472 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
DHGIOLOB_03473 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
DHGIOLOB_03474 3.88e-242 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
DHGIOLOB_03475 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_03476 2.49e-166 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
DHGIOLOB_03477 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
DHGIOLOB_03478 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
DHGIOLOB_03479 7.3e-161 yfmS - - NT - - - chemotaxis protein
DHGIOLOB_03480 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
DHGIOLOB_03481 7.28e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
DHGIOLOB_03482 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
DHGIOLOB_03483 7.24e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
DHGIOLOB_03484 5.23e-35 - - - - - - - -
DHGIOLOB_03485 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
DHGIOLOB_03486 4.19e-263 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
DHGIOLOB_03487 1.53e-97 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
DHGIOLOB_03488 9.5e-239 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
DHGIOLOB_03489 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
DHGIOLOB_03490 2.01e-221 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHGIOLOB_03491 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHGIOLOB_03492 1.17e-220 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
DHGIOLOB_03493 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
DHGIOLOB_03494 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
DHGIOLOB_03495 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
DHGIOLOB_03496 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
DHGIOLOB_03497 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
DHGIOLOB_03498 2.2e-151 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
DHGIOLOB_03499 1.62e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
DHGIOLOB_03500 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
DHGIOLOB_03501 1.7e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
DHGIOLOB_03502 5.59e-275 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DHGIOLOB_03503 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
DHGIOLOB_03504 3.42e-157 yflK - - S - - - protein conserved in bacteria
DHGIOLOB_03505 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
DHGIOLOB_03506 6.9e-27 yflI - - - - - - -
DHGIOLOB_03507 1.48e-65 yflH - - S - - - Protein of unknown function (DUF3243)
DHGIOLOB_03508 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
DHGIOLOB_03509 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
DHGIOLOB_03510 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
DHGIOLOB_03511 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
DHGIOLOB_03512 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
DHGIOLOB_03513 1.36e-32 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
DHGIOLOB_03514 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DHGIOLOB_03515 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
DHGIOLOB_03516 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
DHGIOLOB_03517 6.16e-160 frp - - C - - - nitroreductase
DHGIOLOB_03518 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
DHGIOLOB_03519 2.23e-113 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
DHGIOLOB_03520 5.1e-265 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_03521 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
DHGIOLOB_03522 9.78e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DHGIOLOB_03523 1.03e-66 yfkI - - S - - - gas vesicle protein
DHGIOLOB_03524 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
DHGIOLOB_03525 1.64e-12 - - - - - - - -
DHGIOLOB_03526 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
DHGIOLOB_03527 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
DHGIOLOB_03528 3.69e-189 yfkD - - S - - - YfkD-like protein
DHGIOLOB_03529 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
DHGIOLOB_03530 1.19e-281 yfkA - - S - - - YfkB-like domain
DHGIOLOB_03531 3.26e-36 yfjT - - - - - - -
DHGIOLOB_03532 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
DHGIOLOB_03533 4.43e-190 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
DHGIOLOB_03534 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
DHGIOLOB_03535 7.91e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DHGIOLOB_03536 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DHGIOLOB_03537 3.04e-59 - - - S - - - YfzA-like protein
DHGIOLOB_03538 9.53e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DHGIOLOB_03539 2.53e-106 yfjM - - S - - - Psort location Cytoplasmic, score
DHGIOLOB_03541 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
DHGIOLOB_03542 6.47e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DHGIOLOB_03543 2.22e-260 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DHGIOLOB_03544 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
DHGIOLOB_03545 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
DHGIOLOB_03546 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
DHGIOLOB_03547 1.05e-74 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
DHGIOLOB_03548 1.07e-100 - - - S - - - Family of unknown function (DUF5381)
DHGIOLOB_03549 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
DHGIOLOB_03550 2.5e-185 yfjC - - - - - - -
DHGIOLOB_03551 2.26e-269 yfjB - - - - - - -
DHGIOLOB_03552 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
DHGIOLOB_03555 6.81e-25 - - - S - - - protein conserved in bacteria
DHGIOLOB_03557 4.94e-88 - - - S - - - LXG domain of WXG superfamily
DHGIOLOB_03560 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
DHGIOLOB_03561 8.69e-181 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
DHGIOLOB_03562 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
DHGIOLOB_03563 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
DHGIOLOB_03564 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
DHGIOLOB_03565 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
DHGIOLOB_03566 2.01e-84 yfiD3 - - S - - - DoxX
DHGIOLOB_03567 2e-206 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
DHGIOLOB_03568 4.15e-240 baeS - - T - - - Histidine kinase
DHGIOLOB_03569 1.01e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
DHGIOLOB_03570 5.1e-213 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
DHGIOLOB_03571 1.78e-265 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
DHGIOLOB_03572 4.19e-263 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
DHGIOLOB_03573 1.89e-128 padR - - K - - - transcriptional
DHGIOLOB_03574 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
DHGIOLOB_03575 1.33e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
DHGIOLOB_03576 1.34e-137 yfiR - - K - - - Transcriptional regulator
DHGIOLOB_03577 2.54e-271 yfiS - - EGP - - - Major facilitator superfamily
DHGIOLOB_03578 1.15e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
DHGIOLOB_03579 0.0 yfiU - - EGP - - - the major facilitator superfamily
DHGIOLOB_03580 2.11e-103 yfiV - - K - - - transcriptional
DHGIOLOB_03581 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DHGIOLOB_03582 3.83e-231 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
DHGIOLOB_03583 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHGIOLOB_03584 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DHGIOLOB_03585 1.26e-213 yfhB - - S - - - PhzF family
DHGIOLOB_03586 1.66e-137 yfhC - - C - - - nitroreductase
DHGIOLOB_03587 8.86e-35 yfhD - - S - - - YfhD-like protein
DHGIOLOB_03589 8.92e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
DHGIOLOB_03590 9.32e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
DHGIOLOB_03591 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
DHGIOLOB_03593 2.45e-268 yfhI - - EGP - - - -transporter
DHGIOLOB_03594 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
DHGIOLOB_03595 8.95e-60 yfhJ - - S - - - WVELL protein
DHGIOLOB_03596 1.91e-114 yfhK - - T - - - Bacterial SH3 domain homologues
DHGIOLOB_03597 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
DHGIOLOB_03598 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
DHGIOLOB_03599 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
DHGIOLOB_03600 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
DHGIOLOB_03601 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
DHGIOLOB_03602 1.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
DHGIOLOB_03603 1.73e-48 yfhS - - - - - - -
DHGIOLOB_03604 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DHGIOLOB_03605 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
DHGIOLOB_03606 8.19e-49 ygaB - - S - - - YgaB-like protein
DHGIOLOB_03607 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
DHGIOLOB_03608 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
DHGIOLOB_03609 1.87e-238 ygaE - - S - - - Membrane
DHGIOLOB_03610 1.33e-311 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
DHGIOLOB_03611 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
DHGIOLOB_03612 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
DHGIOLOB_03613 3.38e-73 ygzB - - S - - - UPF0295 protein
DHGIOLOB_03614 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
DHGIOLOB_03615 1.41e-266 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
DHGIOLOB_03616 1.76e-277 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DHGIOLOB_03617 1.98e-233 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DHGIOLOB_03618 5.66e-193 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
DHGIOLOB_03619 5.47e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DHGIOLOB_03620 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DHGIOLOB_03621 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
DHGIOLOB_03622 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
DHGIOLOB_03623 2.66e-102 ypmB - - S - - - protein conserved in bacteria
DHGIOLOB_03624 2.53e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
DHGIOLOB_03625 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
DHGIOLOB_03626 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
DHGIOLOB_03627 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DHGIOLOB_03628 2.37e-120 ypoC - - - - - - -
DHGIOLOB_03629 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
DHGIOLOB_03630 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DHGIOLOB_03631 6.93e-236 yppC - - S - - - Protein of unknown function (DUF2515)
DHGIOLOB_03634 1.42e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
DHGIOLOB_03635 9.21e-11 - - - S - - - YppF-like protein
DHGIOLOB_03636 8.72e-68 yppG - - S - - - YppG-like protein
DHGIOLOB_03637 1.19e-92 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
DHGIOLOB_03638 5.3e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
DHGIOLOB_03639 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
DHGIOLOB_03640 1.7e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
DHGIOLOB_03641 9.4e-128 ypsA - - S - - - Belongs to the UPF0398 family
DHGIOLOB_03642 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DHGIOLOB_03643 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
DHGIOLOB_03645 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
DHGIOLOB_03646 1.88e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DHGIOLOB_03647 1.2e-202 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DHGIOLOB_03648 3.18e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
DHGIOLOB_03649 5.71e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
DHGIOLOB_03650 1.2e-131 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
DHGIOLOB_03651 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
DHGIOLOB_03652 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DHGIOLOB_03653 1.11e-126 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DHGIOLOB_03654 1e-290 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
DHGIOLOB_03655 2.63e-265 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
DHGIOLOB_03656 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
DHGIOLOB_03658 0.0 ypbR - - S - - - Dynamin family
DHGIOLOB_03659 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
DHGIOLOB_03660 1.08e-11 - - - - - - - -
DHGIOLOB_03661 2.26e-213 ypcP - - L - - - 5'3' exonuclease
DHGIOLOB_03662 5.23e-05 - - - - ko:K06429 - ko00000 -
DHGIOLOB_03663 1.6e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
DHGIOLOB_03664 5.2e-156 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DHGIOLOB_03665 2.31e-162 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
DHGIOLOB_03666 1.54e-37 ypeQ - - S - - - Zinc-finger
DHGIOLOB_03667 1.23e-39 - - - S - - - Protein of unknown function (DUF2564)
DHGIOLOB_03668 1.17e-22 degR - - - - - - -
DHGIOLOB_03669 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
DHGIOLOB_03670 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
DHGIOLOB_03671 6.09e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DHGIOLOB_03672 3.66e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
DHGIOLOB_03673 2.94e-141 yagB - - S ko:K06950 - ko00000 phosphohydrolase
DHGIOLOB_03674 4.02e-204 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
DHGIOLOB_03675 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
DHGIOLOB_03676 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
DHGIOLOB_03677 1.19e-184 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
DHGIOLOB_03678 1.41e-147 ypjP - - S - - - YpjP-like protein
DHGIOLOB_03679 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
DHGIOLOB_03680 7.88e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DHGIOLOB_03681 2.24e-141 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
DHGIOLOB_03682 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
DHGIOLOB_03683 1.4e-236 yplP - - K - - - Transcriptional regulator
DHGIOLOB_03684 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DHGIOLOB_03685 2.12e-53 ypmP - - S - - - Protein of unknown function (DUF2535)
DHGIOLOB_03686 7.93e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
DHGIOLOB_03687 1.82e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
DHGIOLOB_03688 1.95e-128 ypmS - - S - - - protein conserved in bacteria
DHGIOLOB_03689 8.69e-40 ypmT - - S - - - Uncharacterized ympT
DHGIOLOB_03690 9.99e-290 mepA - - V - - - MATE efflux family protein
DHGIOLOB_03691 4.14e-94 ypoP - - K - - - transcriptional
DHGIOLOB_03692 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DHGIOLOB_03693 4.13e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
DHGIOLOB_03694 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
DHGIOLOB_03695 9.41e-279 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
DHGIOLOB_03696 2.69e-227 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
DHGIOLOB_03697 1.79e-82 cgeA - - - ko:K06319 - ko00000 -
DHGIOLOB_03698 9.46e-29 cgeC - - - ko:K06321 - ko00000 -
DHGIOLOB_03699 9.12e-13 cgeC - - - ko:K06321 - ko00000 -
DHGIOLOB_03700 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
DHGIOLOB_03701 2.81e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
DHGIOLOB_03702 3.85e-314 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DHGIOLOB_03703 1.62e-159 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DHGIOLOB_03704 3.85e-152 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
DHGIOLOB_03705 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
DHGIOLOB_03706 2.15e-196 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
DHGIOLOB_03707 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
DHGIOLOB_03708 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
DHGIOLOB_03709 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
DHGIOLOB_03710 7.44e-159 yodN - - - - - - -
DHGIOLOB_03712 5.18e-34 yozD - - S - - - YozD-like protein
DHGIOLOB_03713 1.35e-136 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
DHGIOLOB_03714 1.17e-71 yodL - - S - - - YodL-like
DHGIOLOB_03715 2.08e-12 - - - - - - - -
DHGIOLOB_03716 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
DHGIOLOB_03717 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
DHGIOLOB_03718 4.86e-41 yodI - - - - - - -
DHGIOLOB_03719 1.24e-165 yodH - - Q - - - Methyltransferase
DHGIOLOB_03720 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
DHGIOLOB_03721 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DHGIOLOB_03722 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
DHGIOLOB_03723 8.09e-215 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
DHGIOLOB_03724 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
DHGIOLOB_03725 4.53e-139 yodC - - C - - - nitroreductase
DHGIOLOB_03726 2.63e-73 yodB - - K - - - transcriptional
DHGIOLOB_03727 5.64e-84 iolK - - S - - - tautomerase
DHGIOLOB_03728 1.31e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
DHGIOLOB_03729 1.95e-14 - - - - - - - -
DHGIOLOB_03730 8.34e-104 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
DHGIOLOB_03731 2.33e-207 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
DHGIOLOB_03732 1.52e-57 - - - - - - - -
DHGIOLOB_03733 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
DHGIOLOB_03734 3.71e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
DHGIOLOB_03735 1.44e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
DHGIOLOB_03736 1.69e-312 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
DHGIOLOB_03738 3.54e-140 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DHGIOLOB_03739 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
DHGIOLOB_03740 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
DHGIOLOB_03741 1.04e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DHGIOLOB_03742 1.55e-206 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
DHGIOLOB_03743 0.0 yojO - - P - - - Von Willebrand factor
DHGIOLOB_03744 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
DHGIOLOB_03745 2.59e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
DHGIOLOB_03746 3.31e-214 yocS - - S ko:K03453 - ko00000 -transporter
DHGIOLOB_03747 4.35e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
DHGIOLOB_03748 1.12e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
DHGIOLOB_03749 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
DHGIOLOB_03750 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
DHGIOLOB_03751 1.91e-42 yozC - - - - - - -
DHGIOLOB_03752 2.17e-74 yozO - - S - - - Bacterial PH domain
DHGIOLOB_03753 1.83e-49 yocN - - - - - - -
DHGIOLOB_03754 2.94e-55 yozN - - - - - - -
DHGIOLOB_03755 2.69e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
DHGIOLOB_03756 2.02e-43 - - - - - - - -
DHGIOLOB_03757 3.02e-70 yocL - - - - - - -
DHGIOLOB_03758 1.42e-107 yocK - - T - - - general stress protein
DHGIOLOB_03759 5.95e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DHGIOLOB_03760 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
DHGIOLOB_03761 6.78e-174 yocH - - M - - - COG1388 FOG LysM repeat
DHGIOLOB_03762 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DHGIOLOB_03763 4.09e-251 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_03764 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
DHGIOLOB_03765 6.44e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
DHGIOLOB_03766 1.32e-122 yocC - - - - - - -
DHGIOLOB_03767 6.12e-184 - - - - - - - -
DHGIOLOB_03768 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
DHGIOLOB_03769 9.39e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
DHGIOLOB_03770 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
DHGIOLOB_03771 5.2e-121 yobW - - - - - - -
DHGIOLOB_03772 1.37e-220 yobV - - K - - - WYL domain
DHGIOLOB_03773 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
DHGIOLOB_03774 4.49e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
DHGIOLOB_03775 1.26e-126 yobS - - K - - - Transcriptional regulator
DHGIOLOB_03776 5.06e-181 - - - J - - - FR47-like protein
DHGIOLOB_03777 2.39e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
DHGIOLOB_03778 5.01e-69 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
DHGIOLOB_03779 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
DHGIOLOB_03780 1.12e-115 yokH - - G - - - SMI1 / KNR4 family
DHGIOLOB_03781 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
DHGIOLOB_03782 6.69e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
DHGIOLOB_03783 1.66e-52 - - - S - - - SMI1-KNR4 cell-wall
DHGIOLOB_03784 1.65e-127 yokK - - S - - - SMI1 / KNR4 family
DHGIOLOB_03785 1.76e-126 - - - J - - - Acetyltransferase (GNAT) domain
DHGIOLOB_03787 9.73e-49 - - - - - - - -
DHGIOLOB_03789 9.74e-67 - - - S - - - YolD-like protein
DHGIOLOB_03790 2.3e-294 - - - S - - - damaged DNA binding
DHGIOLOB_03792 2.14e-17 - - - Q - - - methyltransferase
DHGIOLOB_03793 4.01e-33 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
DHGIOLOB_03794 0.000751 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
DHGIOLOB_03795 3.91e-52 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DHGIOLOB_03797 1.57e-121 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
DHGIOLOB_03799 9.95e-23 - - - - - - - -
DHGIOLOB_03800 3.23e-86 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
DHGIOLOB_03801 3.12e-98 - - - - - - - -
DHGIOLOB_03803 3.46e-10 ywlA - - S - - - Uncharacterised protein family (UPF0715)
DHGIOLOB_03804 4.98e-106 yoaW - - - - - - -
DHGIOLOB_03805 2.82e-36 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
DHGIOLOB_03806 6.23e-131 - - - S - - - Domain of unknown function (DUF3885)
DHGIOLOB_03807 3.25e-67 ynaF - - - - - - -
DHGIOLOB_03814 1.15e-22 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
DHGIOLOB_03815 1.38e-172 - - - - - - - -
DHGIOLOB_03816 2.49e-43 yoaF - - - - - - -
DHGIOLOB_03818 2.11e-49 - - - S - - - TM2 domain
DHGIOLOB_03819 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
DHGIOLOB_03820 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
DHGIOLOB_03823 2.54e-215 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
DHGIOLOB_03824 2.07e-148 lin0465 - - S - - - DJ-1/PfpI family
DHGIOLOB_03825 3.55e-47 yoaW - - - - - - -
DHGIOLOB_03826 1.4e-42 yoaW - - - - - - -
DHGIOLOB_03827 1.11e-202 yoaV - - EG - - - EamA-like transporter family
DHGIOLOB_03828 5.48e-202 yoaU - - K - - - LysR substrate binding domain
DHGIOLOB_03829 1.63e-190 yoaT - - S - - - Protein of unknown function (DUF817)
DHGIOLOB_03830 1.21e-40 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_03831 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
DHGIOLOB_03832 1.04e-217 yoaR - - V - - - vancomycin resistance protein
DHGIOLOB_03833 2.09e-110 - - - - - - - -
DHGIOLOB_03835 4.41e-293 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
DHGIOLOB_03838 1.7e-169 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
DHGIOLOB_03839 9.68e-251 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
DHGIOLOB_03840 1.79e-145 yoaK - - S - - - Membrane
DHGIOLOB_03841 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
DHGIOLOB_03842 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
DHGIOLOB_03843 2.74e-283 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
DHGIOLOB_03844 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
DHGIOLOB_03845 1.46e-19 - - - - - - - -
DHGIOLOB_03847 1.03e-44 yoaF - - - - - - -
DHGIOLOB_03848 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DHGIOLOB_03849 9.23e-232 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHGIOLOB_03850 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
DHGIOLOB_03851 2.24e-300 yoaB - - EGP - - - the major facilitator superfamily
DHGIOLOB_03852 2.06e-106 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
DHGIOLOB_03853 4.25e-173 yoxB - - - - - - -
DHGIOLOB_03854 5.68e-53 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
DHGIOLOB_03855 2.28e-159 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
DHGIOLOB_03856 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
DHGIOLOB_03857 2.24e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DHGIOLOB_03858 3.04e-258 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DHGIOLOB_03859 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_03860 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
DHGIOLOB_03861 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
DHGIOLOB_03862 1.63e-234 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
DHGIOLOB_03863 2.41e-198 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
DHGIOLOB_03864 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
DHGIOLOB_03865 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
DHGIOLOB_03866 1.14e-124 - - - L - - - Integrase
DHGIOLOB_03868 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
DHGIOLOB_03869 9.8e-313 yoeA - - V - - - MATE efflux family protein
DHGIOLOB_03870 6.71e-241 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
DHGIOLOB_03871 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
DHGIOLOB_03872 2.12e-86 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DHGIOLOB_03873 8.93e-192 ypuA - - S - - - Secreted protein
DHGIOLOB_03874 4.66e-41 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DHGIOLOB_03875 8.64e-97 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DHGIOLOB_03880 7.27e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
DHGIOLOB_03882 7.72e-57 - - - - - - - -
DHGIOLOB_03883 1.15e-302 - - - I - - - Pfam Lipase (class 3)
DHGIOLOB_03884 1.62e-37 - - - S - - - Protein of unknown function (DUF1433)
DHGIOLOB_03886 3.29e-104 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
DHGIOLOB_03887 4.49e-136 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
DHGIOLOB_03891 1.87e-107 - - - S - - - Protein of unknown function (DUF3800)
DHGIOLOB_03892 1.73e-13 - - - - - - - -
DHGIOLOB_03893 3.96e-84 - - - O - - - Papain family cysteine protease
DHGIOLOB_03895 1.22e-29 - - - L ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 DNA/RNA non-specific endonuclease
DHGIOLOB_03896 3.82e-37 - - - - - - - -
DHGIOLOB_03898 8.28e-56 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DHGIOLOB_03900 6.74e-30 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
DHGIOLOB_03902 2.66e-122 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
DHGIOLOB_03903 5.98e-72 ypuD - - - - - - -
DHGIOLOB_03904 1.39e-258 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DHGIOLOB_03905 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
DHGIOLOB_03906 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DHGIOLOB_03907 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
DHGIOLOB_03908 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DHGIOLOB_03909 1.19e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
DHGIOLOB_03910 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DHGIOLOB_03911 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DHGIOLOB_03912 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
DHGIOLOB_03913 9.67e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
DHGIOLOB_03914 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
DHGIOLOB_03915 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
DHGIOLOB_03916 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
DHGIOLOB_03917 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
DHGIOLOB_03918 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
DHGIOLOB_03919 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
DHGIOLOB_03920 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DHGIOLOB_03921 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
DHGIOLOB_03922 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
DHGIOLOB_03923 1.95e-236 rsiX - - - - - - -
DHGIOLOB_03924 4.79e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DHGIOLOB_03925 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHGIOLOB_03926 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DHGIOLOB_03927 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
DHGIOLOB_03928 4.47e-255 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
DHGIOLOB_03929 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
DHGIOLOB_03930 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
DHGIOLOB_03931 8.27e-143 ypbE - - M - - - Lysin motif
DHGIOLOB_03932 4.08e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
DHGIOLOB_03933 6.15e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
DHGIOLOB_03934 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
DHGIOLOB_03935 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
DHGIOLOB_03936 6.04e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
DHGIOLOB_03937 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
DHGIOLOB_03938 1.1e-204 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
DHGIOLOB_03939 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
DHGIOLOB_03940 8.95e-142 ypfA - - M - - - Flagellar protein YcgR
DHGIOLOB_03941 2.48e-32 - - - S - - - Family of unknown function (DUF5359)
DHGIOLOB_03942 3.91e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
DHGIOLOB_03943 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
DHGIOLOB_03944 5.43e-234 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DHGIOLOB_03945 1.13e-11 - - - S - - - YpzI-like protein
DHGIOLOB_03946 3.87e-134 yphA - - - - - - -
DHGIOLOB_03947 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
DHGIOLOB_03948 2.06e-38 ypzH - - - - - - -
DHGIOLOB_03949 1.72e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
DHGIOLOB_03950 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
DHGIOLOB_03951 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
DHGIOLOB_03952 4.31e-176 yphF - - - - - - -
DHGIOLOB_03953 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DHGIOLOB_03954 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DHGIOLOB_03955 2.55e-130 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
DHGIOLOB_03956 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
DHGIOLOB_03957 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
DHGIOLOB_03958 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
DHGIOLOB_03959 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
DHGIOLOB_03960 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
DHGIOLOB_03961 2.13e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
DHGIOLOB_03962 5.88e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DHGIOLOB_03963 5.72e-263 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DHGIOLOB_03964 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
DHGIOLOB_03965 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DHGIOLOB_03966 8.47e-221 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DHGIOLOB_03967 4.18e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
DHGIOLOB_03968 8.71e-148 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
DHGIOLOB_03969 1.81e-292 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DHGIOLOB_03970 3.82e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DHGIOLOB_03971 3.7e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DHGIOLOB_03972 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
DHGIOLOB_03973 1.64e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DHGIOLOB_03974 3.56e-297 ypiA - - S - - - COG0457 FOG TPR repeat
DHGIOLOB_03975 1.83e-129 ypiB - - S - - - Belongs to the UPF0302 family
DHGIOLOB_03976 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
DHGIOLOB_03977 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
DHGIOLOB_03978 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
DHGIOLOB_03979 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
DHGIOLOB_03980 6.63e-125 ypjA - - S - - - membrane
DHGIOLOB_03981 2.79e-182 ypjB - - S - - - sporulation protein
DHGIOLOB_03982 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
DHGIOLOB_03983 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
DHGIOLOB_03984 4.78e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
DHGIOLOB_03985 4.05e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
DHGIOLOB_03986 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
DHGIOLOB_03988 2.16e-14 - - - - - - - -
DHGIOLOB_03990 2.44e-155 - - - - - - - -
DHGIOLOB_03991 4.15e-49 - - - - - - - -
DHGIOLOB_03992 6.63e-122 - - - G - - - SMI1-KNR4 cell-wall
DHGIOLOB_03993 5.75e-124 ynaD - - J - - - Acetyltransferase (GNAT) domain
DHGIOLOB_03994 9.53e-160 - - - S - - - Domain of unknown function (DUF3885)
DHGIOLOB_03995 1.56e-103 - - - E - - - phosphoribosylanthranilate isomerase activity
DHGIOLOB_03996 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
DHGIOLOB_03997 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
DHGIOLOB_03998 5.23e-277 xylR - - GK - - - ROK family
DHGIOLOB_03999 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
DHGIOLOB_04000 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
DHGIOLOB_04001 7.18e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
DHGIOLOB_04002 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DHGIOLOB_04003 5.91e-279 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DHGIOLOB_04005 9.48e-108 - - - S - - - Protein of unknown function (DUF2691)
DHGIOLOB_04006 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
DHGIOLOB_04009 3.91e-210 - - - S - - - Thymidylate synthase
DHGIOLOB_04011 2.17e-165 - - - S - - - Domain of unknown function, YrpD
DHGIOLOB_04014 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
DHGIOLOB_04015 1.04e-94 - - - - - - - -
DHGIOLOB_04016 1.81e-103 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
DHGIOLOB_04019 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
DHGIOLOB_04020 9.26e-249 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
DHGIOLOB_04021 5.12e-285 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
DHGIOLOB_04022 1.2e-194 yndG - - S - - - DoxX-like family
DHGIOLOB_04023 1.21e-149 - - - S - - - Domain of unknown function (DUF4166)
DHGIOLOB_04024 0.0 yndJ - - S - - - YndJ-like protein
DHGIOLOB_04026 2.57e-172 yndL - - S - - - Replication protein
DHGIOLOB_04027 3.79e-96 yndM - - S - - - Protein of unknown function (DUF2512)
DHGIOLOB_04028 2.47e-101 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
DHGIOLOB_04029 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DHGIOLOB_04030 2.44e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
DHGIOLOB_04031 2.29e-144 yneB - - L - - - resolvase
DHGIOLOB_04032 1.15e-43 ynzC - - S - - - UPF0291 protein
DHGIOLOB_04033 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DHGIOLOB_04034 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
DHGIOLOB_04035 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
DHGIOLOB_04036 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
DHGIOLOB_04037 1.68e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
DHGIOLOB_04038 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
DHGIOLOB_04039 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
DHGIOLOB_04040 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
DHGIOLOB_04041 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
DHGIOLOB_04042 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
DHGIOLOB_04043 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
DHGIOLOB_04044 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DHGIOLOB_04045 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DHGIOLOB_04046 9.26e-10 - - - S - - - Fur-regulated basic protein B
DHGIOLOB_04048 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
DHGIOLOB_04049 2.72e-93 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
DHGIOLOB_04050 5.48e-70 yneQ - - - - - - -
DHGIOLOB_04051 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
DHGIOLOB_04052 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DHGIOLOB_04053 1.72e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
DHGIOLOB_04054 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DHGIOLOB_04055 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DHGIOLOB_04056 7.45e-18 - - - - - - - -
DHGIOLOB_04057 8.74e-75 ynfC - - - - - - -
DHGIOLOB_04058 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
DHGIOLOB_04059 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
DHGIOLOB_04061 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
DHGIOLOB_04062 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
DHGIOLOB_04063 9.97e-103 yngA - - S - - - membrane
DHGIOLOB_04064 5.53e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
DHGIOLOB_04065 2.01e-134 yngC - - S - - - membrane-associated protein
DHGIOLOB_04066 7.39e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
DHGIOLOB_04067 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
DHGIOLOB_04068 6.03e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
DHGIOLOB_04069 9.56e-212 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
DHGIOLOB_04070 8.37e-42 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
DHGIOLOB_04071 6.65e-315 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
DHGIOLOB_04072 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
DHGIOLOB_04073 5.35e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
DHGIOLOB_04074 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
DHGIOLOB_04075 2.48e-83 yngL - - S - - - Protein of unknown function (DUF1360)
DHGIOLOB_04076 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
DHGIOLOB_04077 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHGIOLOB_04078 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
DHGIOLOB_04079 2.7e-132 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
DHGIOLOB_04080 8.37e-259 yaaN - - P - - - Belongs to the TelA family
DHGIOLOB_04081 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
DHGIOLOB_04082 1.63e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DHGIOLOB_04083 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
DHGIOLOB_04084 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
DHGIOLOB_04085 9.28e-230 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
DHGIOLOB_04086 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
DHGIOLOB_04087 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
DHGIOLOB_04088 3.28e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
DHGIOLOB_04089 9.89e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
DHGIOLOB_04090 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DHGIOLOB_04091 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
DHGIOLOB_04092 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DHGIOLOB_04093 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
DHGIOLOB_04094 5.57e-276 yabE - - T - - - protein conserved in bacteria
DHGIOLOB_04095 2.03e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DHGIOLOB_04096 2.05e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DHGIOLOB_04097 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
DHGIOLOB_04098 5.32e-53 veg - - S - - - protein conserved in bacteria
DHGIOLOB_04099 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DHGIOLOB_04100 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
DHGIOLOB_04101 1.4e-82 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
DHGIOLOB_04102 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
DHGIOLOB_04103 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DHGIOLOB_04104 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DHGIOLOB_04105 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DHGIOLOB_04106 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DHGIOLOB_04107 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
DHGIOLOB_04108 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DHGIOLOB_04109 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
DHGIOLOB_04110 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
DHGIOLOB_04111 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
DHGIOLOB_04112 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
DHGIOLOB_04113 1.91e-66 yabP - - S - - - Sporulation protein YabP
DHGIOLOB_04114 1.49e-137 yabQ - - S - - - spore cortex biosynthesis protein
DHGIOLOB_04115 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
DHGIOLOB_04116 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
DHGIOLOB_04119 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
DHGIOLOB_04120 1.61e-167 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
DHGIOLOB_04121 1.2e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
DHGIOLOB_04122 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DHGIOLOB_04123 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
DHGIOLOB_04124 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DHGIOLOB_04125 8.08e-188 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DHGIOLOB_04126 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DHGIOLOB_04127 2.07e-205 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
DHGIOLOB_04128 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
DHGIOLOB_04129 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DHGIOLOB_04130 4.92e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
DHGIOLOB_04131 1.32e-215 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
DHGIOLOB_04132 1.11e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DHGIOLOB_04133 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DHGIOLOB_04134 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DHGIOLOB_04135 1.81e-41 yazB - - K - - - transcriptional
DHGIOLOB_04136 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DHGIOLOB_04137 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
DHGIOLOB_04138 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DHGIOLOB_04139 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
DHGIOLOB_04140 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
DHGIOLOB_04141 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DHGIOLOB_04142 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DHGIOLOB_04143 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DHGIOLOB_04144 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DHGIOLOB_04145 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DHGIOLOB_04146 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DHGIOLOB_04147 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DHGIOLOB_04148 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DHGIOLOB_04149 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DHGIOLOB_04150 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
DHGIOLOB_04151 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DHGIOLOB_04152 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DHGIOLOB_04153 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DHGIOLOB_04154 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DHGIOLOB_04155 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DHGIOLOB_04156 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DHGIOLOB_04157 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
DHGIOLOB_04158 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DHGIOLOB_04159 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
DHGIOLOB_04160 2.13e-229 ybaC - - S - - - Alpha/beta hydrolase family
DHGIOLOB_04161 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DHGIOLOB_04162 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DHGIOLOB_04163 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DHGIOLOB_04164 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DHGIOLOB_04165 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
DHGIOLOB_04166 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DHGIOLOB_04167 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DHGIOLOB_04168 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
DHGIOLOB_04169 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DHGIOLOB_04170 5.72e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DHGIOLOB_04171 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DHGIOLOB_04172 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DHGIOLOB_04173 1.19e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
DHGIOLOB_04174 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DHGIOLOB_04175 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
DHGIOLOB_04176 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
DHGIOLOB_04177 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DHGIOLOB_04178 2.04e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DHGIOLOB_04179 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
DHGIOLOB_04180 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
DHGIOLOB_04181 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DHGIOLOB_04182 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
DHGIOLOB_04183 4.29e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DHGIOLOB_04184 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
DHGIOLOB_04185 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DHGIOLOB_04186 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DHGIOLOB_04187 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
DHGIOLOB_04188 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
DHGIOLOB_04189 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
DHGIOLOB_04190 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
DHGIOLOB_04191 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHGIOLOB_04192 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHGIOLOB_04193 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DHGIOLOB_04194 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
DHGIOLOB_04195 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
DHGIOLOB_04196 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DHGIOLOB_04197 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DHGIOLOB_04198 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DHGIOLOB_04199 2.88e-106 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DHGIOLOB_04200 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
DHGIOLOB_04201 4.25e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
DHGIOLOB_04202 8.15e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
DHGIOLOB_04203 3.06e-158 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
DHGIOLOB_04205 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DHGIOLOB_04206 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DHGIOLOB_04207 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DHGIOLOB_04208 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
DHGIOLOB_04209 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DHGIOLOB_04210 2.05e-230 yaaC - - S - - - YaaC-like Protein
DHGIOLOB_04211 8.69e-181 pdaB - - G - - - Polysaccharide deacetylase
DHGIOLOB_04212 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
DHGIOLOB_04213 1.04e-122 gerD - - - ko:K06294 - ko00000 -
DHGIOLOB_04214 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
DHGIOLOB_04215 1.23e-167 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
DHGIOLOB_04216 1.47e-90 ybaK - - S - - - Protein of unknown function (DUF2521)
DHGIOLOB_04217 1.69e-183 ybaJ - - Q - - - Methyltransferase domain
DHGIOLOB_04218 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
DHGIOLOB_04219 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DHGIOLOB_04220 4.33e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DHGIOLOB_04221 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DHGIOLOB_04222 6.34e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DHGIOLOB_04223 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DHGIOLOB_04224 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
DHGIOLOB_04225 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
DHGIOLOB_04226 3.98e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
DHGIOLOB_04227 3.68e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
DHGIOLOB_04228 1.23e-227 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DHGIOLOB_04231 3.84e-255 - - - L - - - COG3666 Transposase and inactivated derivatives
DHGIOLOB_04232 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DHGIOLOB_04233 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
DHGIOLOB_04234 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DHGIOLOB_04235 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DHGIOLOB_04236 1.78e-174 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DHGIOLOB_04237 3.19e-81 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)