ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LHCGIODF_00001 3.97e-49 - - - - - - - -
LHCGIODF_00002 2.93e-260 nicK - - L ko:K07467 - ko00000 Replication initiation factor
LHCGIODF_00003 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
LHCGIODF_00004 7.79e-85 - - - S - - - Bacterial protein of unknown function (DUF961)
LHCGIODF_00006 4.06e-48 - - - - - - - -
LHCGIODF_00007 4.71e-47 - - - - - - - -
LHCGIODF_00008 9.07e-80 - - - K - - - Transcriptional
LHCGIODF_00009 7.82e-118 - - - E - - - Pfam:DUF955
LHCGIODF_00010 2.85e-266 ydcL - - L - - - Belongs to the 'phage' integrase family
LHCGIODF_00018 1.53e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LHCGIODF_00019 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
LHCGIODF_00020 1.04e-99 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHCGIODF_00021 1.32e-106 ydcG - - S - - - EVE domain
LHCGIODF_00024 4.38e-140 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
LHCGIODF_00025 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHCGIODF_00026 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LHCGIODF_00027 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
LHCGIODF_00028 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
LHCGIODF_00029 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LHCGIODF_00030 7.34e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
LHCGIODF_00031 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
LHCGIODF_00032 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LHCGIODF_00033 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LHCGIODF_00034 5.29e-284 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LHCGIODF_00035 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
LHCGIODF_00036 1.95e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LHCGIODF_00037 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
LHCGIODF_00038 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
LHCGIODF_00039 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
LHCGIODF_00040 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LHCGIODF_00041 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LHCGIODF_00042 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LHCGIODF_00043 4.19e-75 ydbP - - CO - - - Thioredoxin
LHCGIODF_00044 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LHCGIODF_00046 1.49e-26 - - - S - - - Fur-regulated basic protein B
LHCGIODF_00047 1.5e-279 ydbM - - I - - - acyl-CoA dehydrogenase
LHCGIODF_00048 9.32e-70 ydbL - - - - - - -
LHCGIODF_00049 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LHCGIODF_00050 2.66e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_00051 1.32e-230 ydbI - - S - - - AI-2E family transporter
LHCGIODF_00052 1.27e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LHCGIODF_00053 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LHCGIODF_00054 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LHCGIODF_00055 3.66e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LHCGIODF_00056 2.24e-197 ydbD - - P ko:K07217 - ko00000 Catalase
LHCGIODF_00057 3.53e-80 ydbC - - S - - - Domain of unknown function (DUF4937
LHCGIODF_00058 1.25e-74 ydbB - - G - - - Cupin domain
LHCGIODF_00059 3.3e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
LHCGIODF_00060 2.49e-189 ydbA - - P - - - EcsC protein family
LHCGIODF_00061 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
LHCGIODF_00062 1.67e-42 ydaS - - S - - - membrane
LHCGIODF_00063 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LHCGIODF_00064 2.14e-53 - - - - - - - -
LHCGIODF_00066 2.18e-90 sdpB - - S - - - Protein conserved in bacteria
LHCGIODF_00067 1.84e-34 - - - - - - - -
LHCGIODF_00069 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LHCGIODF_00070 1.79e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LHCGIODF_00071 0.0 ydaO - - E - - - amino acid
LHCGIODF_00072 2.66e-310 ydaN - - S - - - Bacterial cellulose synthase subunit
LHCGIODF_00073 1.73e-143 ydaN - - S - - - Bacterial cellulose synthase subunit
LHCGIODF_00074 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
LHCGIODF_00075 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
LHCGIODF_00076 9.39e-195 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
LHCGIODF_00077 1.03e-265 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
LHCGIODF_00078 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LHCGIODF_00079 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LHCGIODF_00080 3.12e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
LHCGIODF_00081 1.87e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LHCGIODF_00082 5.24e-101 ydaG - - S - - - general stress protein
LHCGIODF_00083 2.58e-131 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LHCGIODF_00084 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
LHCGIODF_00085 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHCGIODF_00086 6.78e-126 ydaC - - Q - - - Methyltransferase domain
LHCGIODF_00087 0.0 ydaB - - IQ - - - acyl-CoA ligase
LHCGIODF_00088 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
LHCGIODF_00089 2.57e-221 ycsN - - S - - - Oxidoreductase
LHCGIODF_00090 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
LHCGIODF_00091 8.97e-65 yczJ - - S - - - biosynthesis
LHCGIODF_00093 1.91e-150 ycsK - - E - - - anatomical structure formation involved in morphogenesis
LHCGIODF_00094 3.8e-171 kipR - - K - - - Transcriptional regulator
LHCGIODF_00095 1.91e-236 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
LHCGIODF_00096 2.05e-172 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
LHCGIODF_00097 2.01e-189 ycsI - - S - - - Belongs to the D-glutamate cyclase family
LHCGIODF_00098 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
LHCGIODF_00099 3.14e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
LHCGIODF_00100 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LHCGIODF_00102 1.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
LHCGIODF_00103 3.32e-141 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
LHCGIODF_00104 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LHCGIODF_00106 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
LHCGIODF_00107 1.21e-265 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
LHCGIODF_00108 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LHCGIODF_00109 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
LHCGIODF_00110 9.44e-75 - - - - - - - -
LHCGIODF_00111 4.98e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LHCGIODF_00112 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
LHCGIODF_00113 8.06e-134 ycnI - - S - - - protein conserved in bacteria
LHCGIODF_00114 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHCGIODF_00115 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
LHCGIODF_00116 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LHCGIODF_00117 9.35e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LHCGIODF_00118 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LHCGIODF_00119 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LHCGIODF_00120 1.68e-60 ycnE - - S - - - Monooxygenase
LHCGIODF_00121 8.65e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LHCGIODF_00122 2.91e-198 ycnC - - K - - - Transcriptional regulator
LHCGIODF_00123 0.0 ycnB - - EGP - - - the major facilitator superfamily
LHCGIODF_00124 5.72e-213 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
LHCGIODF_00125 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_00126 4.49e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHCGIODF_00127 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHCGIODF_00128 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LHCGIODF_00129 7.93e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LHCGIODF_00130 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LHCGIODF_00132 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LHCGIODF_00133 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LHCGIODF_00134 4.5e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHCGIODF_00135 6.2e-277 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
LHCGIODF_00136 5.87e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LHCGIODF_00137 1.33e-253 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
LHCGIODF_00138 1.97e-295 gerKC - - S ko:K06297 - ko00000 spore germination
LHCGIODF_00139 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
LHCGIODF_00141 0.0 yclG - - M - - - Pectate lyase superfamily protein
LHCGIODF_00142 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
LHCGIODF_00143 5.5e-202 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
LHCGIODF_00144 2.32e-104 yclD - - - - - - -
LHCGIODF_00145 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
LHCGIODF_00146 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LHCGIODF_00147 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LHCGIODF_00148 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
LHCGIODF_00149 3.03e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LHCGIODF_00150 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LHCGIODF_00151 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LHCGIODF_00152 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
LHCGIODF_00153 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
LHCGIODF_00154 0.0 ycxD - - K - - - GntR family transcriptional regulator
LHCGIODF_00155 3.27e-205 ycxC - - EG - - - EamA-like transporter family
LHCGIODF_00156 2.99e-122 - - - S - - - YcxB-like protein
LHCGIODF_00157 2.55e-287 - - - EGP - - - Major Facilitator Superfamily
LHCGIODF_00158 3.3e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
LHCGIODF_00159 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
LHCGIODF_00160 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHCGIODF_00161 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHCGIODF_00162 6.05e-86 hxlR - - K - - - transcriptional
LHCGIODF_00163 8e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
LHCGIODF_00164 1.54e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
LHCGIODF_00165 1.52e-267 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHCGIODF_00166 3.23e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
LHCGIODF_00167 4.78e-91 nin - - S - - - Competence protein J (ComJ)
LHCGIODF_00168 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHCGIODF_00169 1.16e-154 - - - S - - - AAA domain
LHCGIODF_00170 9e-32 - - - - - - - -
LHCGIODF_00171 7.43e-58 - - - K - - - MarR family
LHCGIODF_00172 4.82e-67 yckD - - S - - - Protein of unknown function (DUF2680)
LHCGIODF_00173 1.38e-47 yckC - - S - - - membrane
LHCGIODF_00175 3.09e-186 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
LHCGIODF_00176 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LHCGIODF_00177 6.78e-291 yciC - - S - - - GTPases (G3E family)
LHCGIODF_00178 2.1e-140 - - - M - - - ErfK YbiS YcfS YnhG
LHCGIODF_00179 2.76e-218 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
LHCGIODF_00180 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LHCGIODF_00181 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
LHCGIODF_00182 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LHCGIODF_00183 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LHCGIODF_00184 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
LHCGIODF_00185 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LHCGIODF_00186 5.3e-239 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LHCGIODF_00187 1.46e-203 ycgS - - I - - - alpha/beta hydrolase fold
LHCGIODF_00188 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
LHCGIODF_00189 3.14e-194 ycgQ - - S ko:K08986 - ko00000 membrane
LHCGIODF_00190 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
LHCGIODF_00191 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LHCGIODF_00192 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LHCGIODF_00193 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LHCGIODF_00194 4.49e-186 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
LHCGIODF_00195 1.29e-230 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
LHCGIODF_00196 5.4e-226 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
LHCGIODF_00197 3.05e-185 - - - Q - - - ubiE/COQ5 methyltransferase family
LHCGIODF_00198 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LHCGIODF_00199 1.31e-140 tmrB - - S - - - AAA domain
LHCGIODF_00200 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LHCGIODF_00201 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
LHCGIODF_00202 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LHCGIODF_00203 1.85e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
LHCGIODF_00204 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
LHCGIODF_00205 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHCGIODF_00206 0.0 mdr - - EGP - - - the major facilitator superfamily
LHCGIODF_00207 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LHCGIODF_00208 1.19e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LHCGIODF_00209 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
LHCGIODF_00210 1.25e-127 ycgB - - - - - - -
LHCGIODF_00211 0.0 ycgA - - S - - - Membrane
LHCGIODF_00212 1.69e-277 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
LHCGIODF_00213 1.65e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LHCGIODF_00214 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LHCGIODF_00215 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
LHCGIODF_00216 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LHCGIODF_00217 1.42e-204 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
LHCGIODF_00218 1.9e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
LHCGIODF_00219 2.96e-245 yceH - - P - - - Belongs to the TelA family
LHCGIODF_00220 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
LHCGIODF_00221 4.1e-176 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
LHCGIODF_00222 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LHCGIODF_00223 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LHCGIODF_00224 3.75e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
LHCGIODF_00225 6.65e-235 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHCGIODF_00226 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LHCGIODF_00227 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LHCGIODF_00228 4.58e-220 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LHCGIODF_00229 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LHCGIODF_00230 6.85e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
LHCGIODF_00231 1.16e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
LHCGIODF_00232 2.18e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LHCGIODF_00233 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHCGIODF_00234 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHCGIODF_00235 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
LHCGIODF_00236 1.13e-220 yccK - - C - - - Aldo keto reductase
LHCGIODF_00237 4.43e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LHCGIODF_00238 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LHCGIODF_00239 5.64e-162 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LHCGIODF_00240 2.3e-208 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LHCGIODF_00241 8.33e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
LHCGIODF_00242 8.72e-78 - - - S - - - RDD family
LHCGIODF_00243 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
LHCGIODF_00244 1.69e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LHCGIODF_00245 1.54e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LHCGIODF_00246 1.24e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
LHCGIODF_00247 2.16e-262 ycbU - - E - - - Selenocysteine lyase
LHCGIODF_00248 5.7e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LHCGIODF_00249 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LHCGIODF_00250 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LHCGIODF_00251 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
LHCGIODF_00252 4.66e-175 ycbR - - T - - - vWA found in TerF C terminus
LHCGIODF_00253 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
LHCGIODF_00254 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
LHCGIODF_00255 2.87e-148 - - - S - - - ABC-2 family transporter protein
LHCGIODF_00256 1.52e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_00257 1.46e-212 ycbM - - T - - - Histidine kinase
LHCGIODF_00258 2.61e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHCGIODF_00259 9.95e-216 eamA1 - - EG - - - spore germination
LHCGIODF_00260 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
LHCGIODF_00261 1.74e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
LHCGIODF_00262 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
LHCGIODF_00263 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
LHCGIODF_00264 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LHCGIODF_00265 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LHCGIODF_00266 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LHCGIODF_00267 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
LHCGIODF_00268 9.96e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
LHCGIODF_00269 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_00270 5.08e-237 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LHCGIODF_00271 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LHCGIODF_00272 8.72e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
LHCGIODF_00273 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LHCGIODF_00274 3.44e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LHCGIODF_00276 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
LHCGIODF_00277 3.52e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LHCGIODF_00278 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHCGIODF_00279 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LHCGIODF_00280 6.73e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
LHCGIODF_00281 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
LHCGIODF_00282 1.58e-59 ybfN - - - - - - -
LHCGIODF_00283 2.06e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LHCGIODF_00284 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
LHCGIODF_00285 2.81e-123 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LHCGIODF_00286 5.56e-214 - - - S - - - Alpha/beta hydrolase family
LHCGIODF_00288 6.86e-228 mpr - - M - - - Belongs to the peptidase S1B family
LHCGIODF_00289 1.46e-267 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LHCGIODF_00290 4.12e-73 - - - - - - - -
LHCGIODF_00291 1.93e-122 - - GH19 M ko:K03791 - ko00000 Lysin motif
LHCGIODF_00292 2.73e-28 xhlB - - S - - - SPP1 phage holin
LHCGIODF_00293 1.27e-43 - - - K - - - sigma factor activity
LHCGIODF_00294 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
LHCGIODF_00295 3.56e-206 ybfH - - EG - - - EamA-like transporter family
LHCGIODF_00296 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
LHCGIODF_00299 2.63e-284 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
LHCGIODF_00300 7.04e-217 ybfA - - K - - - FR47-like protein
LHCGIODF_00301 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
LHCGIODF_00302 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
LHCGIODF_00303 1.36e-208 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
LHCGIODF_00304 0.0 ybeC - - E - - - amino acid
LHCGIODF_00305 1.3e-53 ybyB - - - - - - -
LHCGIODF_00306 3.8e-314 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
LHCGIODF_00307 7.18e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
LHCGIODF_00308 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
LHCGIODF_00309 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
LHCGIODF_00310 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LHCGIODF_00311 3.18e-300 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LHCGIODF_00312 1.77e-32 yqzJ - - - - - - -
LHCGIODF_00313 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LHCGIODF_00314 5.7e-180 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
LHCGIODF_00315 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
LHCGIODF_00316 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LHCGIODF_00317 2.22e-93 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
LHCGIODF_00319 9.84e-128 yqjB - - S - - - protein conserved in bacteria
LHCGIODF_00320 3.49e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
LHCGIODF_00321 1.49e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LHCGIODF_00322 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LHCGIODF_00323 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LHCGIODF_00324 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
LHCGIODF_00325 1.21e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LHCGIODF_00326 1.79e-266 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LHCGIODF_00327 3.03e-193 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
LHCGIODF_00328 2.09e-285 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LHCGIODF_00329 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LHCGIODF_00330 1.11e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LHCGIODF_00331 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LHCGIODF_00332 1.96e-254 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
LHCGIODF_00333 6.41e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LHCGIODF_00334 3.52e-198 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
LHCGIODF_00335 0.0 bkdR - - KT - - - Transcriptional regulator
LHCGIODF_00336 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
LHCGIODF_00337 8.8e-209 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LHCGIODF_00338 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
LHCGIODF_00339 1.85e-264 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LHCGIODF_00340 2.86e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
LHCGIODF_00341 6.9e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
LHCGIODF_00342 1.83e-277 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LHCGIODF_00343 3.39e-168 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LHCGIODF_00344 9.4e-138 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
LHCGIODF_00345 2.26e-37 - - - - - - - -
LHCGIODF_00346 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LHCGIODF_00348 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LHCGIODF_00349 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
LHCGIODF_00350 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LHCGIODF_00351 3.08e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LHCGIODF_00352 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
LHCGIODF_00353 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LHCGIODF_00354 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LHCGIODF_00355 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LHCGIODF_00356 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LHCGIODF_00357 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LHCGIODF_00358 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LHCGIODF_00359 9.55e-88 yqhY - - S - - - protein conserved in bacteria
LHCGIODF_00360 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LHCGIODF_00361 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LHCGIODF_00362 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
LHCGIODF_00363 1.08e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
LHCGIODF_00364 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
LHCGIODF_00365 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
LHCGIODF_00366 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
LHCGIODF_00367 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
LHCGIODF_00368 9.44e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
LHCGIODF_00369 1.66e-216 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
LHCGIODF_00370 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
LHCGIODF_00371 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LHCGIODF_00372 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LHCGIODF_00373 2.75e-100 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
LHCGIODF_00374 9.37e-120 yqhR - - S - - - Conserved membrane protein YqhR
LHCGIODF_00375 2.98e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
LHCGIODF_00376 5.18e-81 yqhP - - - - - - -
LHCGIODF_00377 4.93e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LHCGIODF_00378 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LHCGIODF_00379 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LHCGIODF_00380 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
LHCGIODF_00381 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LHCGIODF_00382 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LHCGIODF_00383 7.79e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
LHCGIODF_00384 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LHCGIODF_00385 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
LHCGIODF_00386 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
LHCGIODF_00387 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
LHCGIODF_00388 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
LHCGIODF_00389 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
LHCGIODF_00390 4.43e-153 yqxM - - - ko:K19433 - ko00000 -
LHCGIODF_00391 3.05e-69 yqzG - - S - - - Protein of unknown function (DUF3889)
LHCGIODF_00392 4.9e-37 yqzE - - S - - - YqzE-like protein
LHCGIODF_00393 1.08e-56 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
LHCGIODF_00394 1.67e-45 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
LHCGIODF_00395 7.23e-78 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
LHCGIODF_00396 9.32e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
LHCGIODF_00397 1.53e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
LHCGIODF_00398 6.56e-214 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
LHCGIODF_00399 2.13e-255 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LHCGIODF_00400 2.13e-05 - - - T - - - CBS domain
LHCGIODF_00401 7.17e-232 yqxL - - P - - - Mg2 transporter protein
LHCGIODF_00402 1.36e-303 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LHCGIODF_00403 8.33e-191 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LHCGIODF_00405 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
LHCGIODF_00406 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
LHCGIODF_00407 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
LHCGIODF_00408 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
LHCGIODF_00409 7.34e-66 yqgV - - S - - - Thiamine-binding protein
LHCGIODF_00410 5.42e-256 yqgU - - - - - - -
LHCGIODF_00411 4.14e-281 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
LHCGIODF_00412 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LHCGIODF_00413 2.31e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LHCGIODF_00414 1.07e-43 yqgQ - - S - - - Protein conserved in bacteria
LHCGIODF_00415 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
LHCGIODF_00416 3.38e-14 yqgO - - - - - - -
LHCGIODF_00417 4.27e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LHCGIODF_00418 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LHCGIODF_00419 1.05e-252 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
LHCGIODF_00421 3.42e-68 yqzD - - - - - - -
LHCGIODF_00422 6.33e-93 yqzC - - S - - - YceG-like family
LHCGIODF_00423 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LHCGIODF_00424 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LHCGIODF_00425 8.71e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
LHCGIODF_00426 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LHCGIODF_00427 4.32e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LHCGIODF_00428 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
LHCGIODF_00429 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
LHCGIODF_00430 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
LHCGIODF_00431 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
LHCGIODF_00432 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
LHCGIODF_00433 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
LHCGIODF_00434 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LHCGIODF_00435 2.04e-81 yqfX - - S - - - membrane
LHCGIODF_00436 4.78e-141 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
LHCGIODF_00437 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
LHCGIODF_00438 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LHCGIODF_00439 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
LHCGIODF_00440 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LHCGIODF_00441 3.13e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LHCGIODF_00442 3.36e-49 yqfQ - - S - - - YqfQ-like protein
LHCGIODF_00443 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LHCGIODF_00444 1.08e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LHCGIODF_00445 1.1e-146 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LHCGIODF_00446 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LHCGIODF_00447 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LHCGIODF_00448 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LHCGIODF_00449 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
LHCGIODF_00450 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LHCGIODF_00451 3.29e-144 ccpN - - K - - - CBS domain
LHCGIODF_00452 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LHCGIODF_00453 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LHCGIODF_00454 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LHCGIODF_00455 5.29e-27 - - - S - - - YqzL-like protein
LHCGIODF_00456 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LHCGIODF_00457 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LHCGIODF_00458 2.75e-79 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LHCGIODF_00459 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LHCGIODF_00460 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
LHCGIODF_00462 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
LHCGIODF_00463 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
LHCGIODF_00464 2.07e-60 yqfC - - S - - - sporulation protein YqfC
LHCGIODF_00465 5.2e-78 yqfB - - - - - - -
LHCGIODF_00466 4.35e-192 yqfA - - S - - - UPF0365 protein
LHCGIODF_00467 5.14e-288 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
LHCGIODF_00468 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
LHCGIODF_00469 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LHCGIODF_00470 3.45e-202 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
LHCGIODF_00471 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
LHCGIODF_00472 1.01e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LHCGIODF_00473 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
LHCGIODF_00474 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LHCGIODF_00475 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LHCGIODF_00476 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LHCGIODF_00477 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LHCGIODF_00478 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
LHCGIODF_00479 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LHCGIODF_00480 6.28e-73 yqxA - - S - - - Protein of unknown function (DUF3679)
LHCGIODF_00481 9.53e-284 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
LHCGIODF_00482 4.16e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LHCGIODF_00483 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LHCGIODF_00484 9.55e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LHCGIODF_00485 2.36e-22 - - - S - - - YqzM-like protein
LHCGIODF_00486 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LHCGIODF_00487 2.67e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
LHCGIODF_00488 2.35e-127 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
LHCGIODF_00489 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LHCGIODF_00490 4.66e-177 yqeM - - Q - - - Methyltransferase
LHCGIODF_00491 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LHCGIODF_00492 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
LHCGIODF_00493 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LHCGIODF_00494 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
LHCGIODF_00495 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LHCGIODF_00496 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LHCGIODF_00497 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
LHCGIODF_00499 1.84e-181 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
LHCGIODF_00500 2.05e-177 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
LHCGIODF_00501 8.6e-131 yqeD - - S - - - SNARE associated Golgi protein
LHCGIODF_00502 8.54e-214 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
LHCGIODF_00503 5.21e-168 - - - - - - - -
LHCGIODF_00504 7.25e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
LHCGIODF_00505 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHCGIODF_00506 0.0 - - - L ko:K06400 - ko00000 Recombinase
LHCGIODF_00507 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
LHCGIODF_00508 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
LHCGIODF_00509 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHCGIODF_00510 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
LHCGIODF_00511 1.7e-187 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
LHCGIODF_00512 3.5e-119 - - - S - - - Tetratricopeptide repeat
LHCGIODF_00515 1.13e-199 - - - S - - - Bacterial EndoU nuclease
LHCGIODF_00516 8.71e-20 - - - S - - - SMI1 / KNR4 family
LHCGIODF_00517 2.88e-61 - - - - - - - -
LHCGIODF_00518 7.3e-131 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
LHCGIODF_00520 5.4e-80 - - - - - - - -
LHCGIODF_00522 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LHCGIODF_00523 1.19e-88 - - - S - - - Bacteriophage holin family
LHCGIODF_00524 2.45e-213 xepA - - - - - - -
LHCGIODF_00525 2.51e-28 - - - - - - - -
LHCGIODF_00526 1.38e-71 xkdW - - S - - - XkdW protein
LHCGIODF_00527 2.96e-246 - - - - - - - -
LHCGIODF_00528 4.62e-49 - - - - - - - -
LHCGIODF_00529 2.74e-126 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
LHCGIODF_00530 6.67e-239 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LHCGIODF_00531 6.6e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
LHCGIODF_00532 8.16e-42 xkdR - - S - - - Protein of unknown function (DUF2577)
LHCGIODF_00533 8.96e-226 xkdQ - - G - - - NLP P60 protein
LHCGIODF_00534 6.29e-154 xkdP - - S - - - Lysin motif
LHCGIODF_00535 0.0 xkdO - - L - - - Transglycosylase SLT domain
LHCGIODF_00536 1.12e-23 - - - - - - - -
LHCGIODF_00537 1.27e-89 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
LHCGIODF_00538 4.23e-99 xkdM - - S - - - Phage tail tube protein
LHCGIODF_00539 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
LHCGIODF_00540 1.21e-34 - - - - - - - -
LHCGIODF_00541 1.48e-98 yqbJ - - - - - - -
LHCGIODF_00542 8.84e-113 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LHCGIODF_00543 3.38e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
LHCGIODF_00544 1.43e-87 - - - S - - - Protein of unknown function (DUF3199)
LHCGIODF_00545 2.12e-60 - - - S - - - YqbF, hypothetical protein domain
LHCGIODF_00546 7.57e-215 xkdG - - S - - - Phage capsid family
LHCGIODF_00547 4.23e-158 yqbD - - L - - - Putative phage serine protease XkdF
LHCGIODF_00548 5.03e-90 - - - S - - - Phage Mu protein F like protein
LHCGIODF_00549 2.65e-196 - - - S - - - Phage Mu protein F like protein
LHCGIODF_00550 0.0 yqbA - - S - - - portal protein
LHCGIODF_00551 1.33e-312 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
LHCGIODF_00552 5.28e-112 yqaS - - L - - - DNA packaging
LHCGIODF_00553 1.19e-85 - - - S - - - Region found in RelA / SpoT proteins
LHCGIODF_00558 1.25e-102 yqaQ - - L - - - Transposase
LHCGIODF_00559 2.06e-61 - - - S - - - Beta protein
LHCGIODF_00560 4.33e-70 - - - S - - - Psort location Cytoplasmic, score
LHCGIODF_00561 2.4e-41 yqaO - - S - - - Phage-like element PBSX protein XtrA
LHCGIODF_00562 9.37e-96 rusA - - L - - - Endodeoxyribonuclease RusA
LHCGIODF_00564 3.55e-207 yqaM - - L - - - IstB-like ATP binding protein
LHCGIODF_00565 5.29e-156 yqaL - - L - - - DnaD domain protein
LHCGIODF_00566 2.79e-192 recT - - L ko:K07455 - ko00000,ko03400 RecT family
LHCGIODF_00567 3.18e-213 yqaJ - - L - - - YqaJ-like viral recombinase domain
LHCGIODF_00571 1.27e-134 - - - - - - - -
LHCGIODF_00573 5.37e-25 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
LHCGIODF_00574 1.88e-42 - - - K - - - sequence-specific DNA binding
LHCGIODF_00576 6.63e-127 yqaC - - F - - - adenylate kinase activity
LHCGIODF_00577 5.51e-123 xkdA - - E - - - IrrE N-terminal-like domain
LHCGIODF_00578 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHCGIODF_00579 1.48e-81 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
LHCGIODF_00580 4.05e-303 yrkQ - - T - - - Histidine kinase
LHCGIODF_00581 7.15e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
LHCGIODF_00582 7.21e-281 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
LHCGIODF_00583 8.99e-133 yrkN - - K - - - Acetyltransferase (GNAT) family
LHCGIODF_00584 4.7e-125 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
LHCGIODF_00585 2.21e-102 - - - S - - - Protein of unknown function with HXXEE motif
LHCGIODF_00586 6.63e-162 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
LHCGIODF_00587 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
LHCGIODF_00588 9.59e-269 yrkH - - P - - - Rhodanese Homology Domain
LHCGIODF_00589 0.000112 perX - - S - - - DsrE/DsrF-like family
LHCGIODF_00590 4.61e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
LHCGIODF_00591 6.83e-109 yrkE - - O - - - DsrE/DsrF/DrsH-like family
LHCGIODF_00592 4.38e-52 yrkD - - S - - - protein conserved in bacteria
LHCGIODF_00593 3.32e-28 - - - - - - - -
LHCGIODF_00594 1.28e-137 yrkC - - G - - - Cupin domain
LHCGIODF_00595 4.42e-185 bltR - - K - - - helix_turn_helix, mercury resistance
LHCGIODF_00596 2.17e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LHCGIODF_00597 2.16e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
LHCGIODF_00598 1.33e-293 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LHCGIODF_00599 2.45e-23 - - - S - - - YrzO-like protein
LHCGIODF_00600 2.84e-215 yrdR - - EG - - - EamA-like transporter family
LHCGIODF_00601 1.15e-202 - - - K - - - Transcriptional regulator
LHCGIODF_00602 1.23e-253 trkA - - P ko:K07222 - ko00000 Oxidoreductase
LHCGIODF_00603 1.88e-200 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
LHCGIODF_00605 1.01e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LHCGIODF_00606 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
LHCGIODF_00607 9.34e-176 azlC - - E - - - AzlC protein
LHCGIODF_00608 4.13e-104 bkdR - - K - - - helix_turn_helix ASNC type
LHCGIODF_00609 1.76e-22 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
LHCGIODF_00610 1.08e-289 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LHCGIODF_00612 4.27e-130 yrdC - - Q - - - Isochorismatase family
LHCGIODF_00613 1.04e-71 - - - S - - - Protein of unknown function (DUF2568)
LHCGIODF_00614 2.01e-118 yrdA - - S - - - DinB family
LHCGIODF_00615 8.54e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
LHCGIODF_00616 4.23e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LHCGIODF_00617 1.56e-184 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LHCGIODF_00618 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
LHCGIODF_00619 2.34e-128 - - - K ko:K05799 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
LHCGIODF_00621 1.94e-266 - - - P - - - Major Facilitator Superfamily
LHCGIODF_00622 1.7e-145 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHCGIODF_00623 6.83e-191 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
LHCGIODF_00624 3.67e-174 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG3959 Transketolase, N-terminal subunit
LHCGIODF_00626 7.88e-281 yfjF - - EGP - - - Belongs to the major facilitator superfamily
LHCGIODF_00627 1.51e-85 napB - - K - - - MarR family transcriptional regulator
LHCGIODF_00628 1.26e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
LHCGIODF_00629 1.1e-124 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHCGIODF_00630 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
LHCGIODF_00631 2.63e-286 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LHCGIODF_00632 2.97e-210 yraN - - K - - - Transcriptional regulator
LHCGIODF_00633 7.18e-259 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LHCGIODF_00634 4.53e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHCGIODF_00635 7.15e-316 yhdG - - E ko:K03294 - ko00000 amino acid
LHCGIODF_00636 2.04e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LHCGIODF_00637 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LHCGIODF_00638 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHCGIODF_00639 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
LHCGIODF_00640 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
LHCGIODF_00641 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHCGIODF_00642 6.74e-244 yhdN - - C - - - Aldo keto reductase
LHCGIODF_00643 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LHCGIODF_00644 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LHCGIODF_00645 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
LHCGIODF_00646 2.08e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LHCGIODF_00647 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
LHCGIODF_00648 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LHCGIODF_00649 1.38e-85 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LHCGIODF_00650 1.05e-171 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LHCGIODF_00651 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
LHCGIODF_00652 1.06e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
LHCGIODF_00653 2.7e-176 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LHCGIODF_00654 1.18e-192 nodB1 - - G - - - deacetylase
LHCGIODF_00655 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LHCGIODF_00656 3.77e-305 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LHCGIODF_00657 9.07e-108 nhaX - - T - - - Belongs to the universal stress protein A family
LHCGIODF_00658 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LHCGIODF_00659 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LHCGIODF_00660 1.11e-141 yheG - - GM - - - NAD(P)H-binding
LHCGIODF_00661 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
LHCGIODF_00662 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
LHCGIODF_00663 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
LHCGIODF_00664 1.6e-274 yheC - - HJ - - - YheC/D like ATP-grasp
LHCGIODF_00665 1.45e-259 yheB - - S - - - Belongs to the UPF0754 family
LHCGIODF_00666 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
LHCGIODF_00667 1.06e-260 yhaZ - - L - - - DNA alkylation repair enzyme
LHCGIODF_00668 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
LHCGIODF_00669 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
LHCGIODF_00670 2.63e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
LHCGIODF_00671 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LHCGIODF_00673 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
LHCGIODF_00674 2.29e-36 - - - S - - - YhzD-like protein
LHCGIODF_00675 3.22e-214 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_00676 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
LHCGIODF_00677 9.44e-301 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
LHCGIODF_00678 0.0 yhaN - - L - - - AAA domain
LHCGIODF_00679 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
LHCGIODF_00680 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
LHCGIODF_00681 2.33e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LHCGIODF_00682 3.3e-115 yhaK - - S - - - Putative zincin peptidase
LHCGIODF_00683 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
LHCGIODF_00684 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
LHCGIODF_00685 1.74e-54 yhaH - - S - - - YtxH-like protein
LHCGIODF_00686 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
LHCGIODF_00687 1.24e-260 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LHCGIODF_00688 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LHCGIODF_00689 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
LHCGIODF_00690 1.27e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LHCGIODF_00691 4.11e-161 ecsC - - S - - - EcsC protein family
LHCGIODF_00692 6.27e-291 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LHCGIODF_00693 9.42e-313 yhfA - - C - - - membrane
LHCGIODF_00694 5.85e-38 - - - C - - - Rubrerythrin
LHCGIODF_00695 1.53e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
LHCGIODF_00696 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LHCGIODF_00697 1.24e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LHCGIODF_00698 4.65e-229 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
LHCGIODF_00699 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LHCGIODF_00700 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_00701 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
LHCGIODF_00702 1.77e-236 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LHCGIODF_00703 2.11e-174 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
LHCGIODF_00705 1.27e-251 yhfE - - G - - - peptidase M42
LHCGIODF_00706 1.53e-93 - - - S - - - ASCH
LHCGIODF_00707 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LHCGIODF_00708 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LHCGIODF_00709 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LHCGIODF_00710 1.18e-140 yhfK - - GM - - - NmrA-like family
LHCGIODF_00711 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LHCGIODF_00712 2.78e-85 yhfM - - - - - - -
LHCGIODF_00713 5.76e-301 yhfN - - O - - - Peptidase M48
LHCGIODF_00714 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LHCGIODF_00715 2.17e-102 - - - K - - - acetyltransferase
LHCGIODF_00716 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
LHCGIODF_00717 1.53e-220 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LHCGIODF_00718 1.95e-140 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
LHCGIODF_00719 1.39e-255 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LHCGIODF_00720 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LHCGIODF_00721 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LHCGIODF_00722 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
LHCGIODF_00723 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
LHCGIODF_00724 2.24e-203 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHCGIODF_00725 9.84e-45 yhzC - - S - - - IDEAL
LHCGIODF_00726 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
LHCGIODF_00727 1.04e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LHCGIODF_00728 2.04e-56 yhjA - - S - - - Excalibur calcium-binding domain
LHCGIODF_00729 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LHCGIODF_00730 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
LHCGIODF_00731 4.13e-78 yhjD - - - - - - -
LHCGIODF_00732 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
LHCGIODF_00733 1.79e-117 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LHCGIODF_00734 0.0 yhjG - - CH - - - FAD binding domain
LHCGIODF_00735 4.01e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHCGIODF_00738 1.49e-270 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
LHCGIODF_00739 1.14e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LHCGIODF_00740 1.07e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
LHCGIODF_00741 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
LHCGIODF_00742 2.07e-237 yhjM - - K - - - Transcriptional regulator
LHCGIODF_00743 2.5e-259 yhjN - - S ko:K07120 - ko00000 membrane
LHCGIODF_00744 9.56e-268 - - - EGP - - - Transmembrane secretion effector
LHCGIODF_00745 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
LHCGIODF_00746 3.54e-77 yhjQ - - C - - - COG1145 Ferredoxin
LHCGIODF_00747 3e-98 yhjR - - S - - - Rubrerythrin
LHCGIODF_00748 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
LHCGIODF_00749 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LHCGIODF_00750 1.4e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LHCGIODF_00751 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
LHCGIODF_00752 1.84e-64 yisB - - V - - - COG1403 Restriction endonuclease
LHCGIODF_00753 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
LHCGIODF_00754 4.58e-85 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
LHCGIODF_00755 1.49e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
LHCGIODF_00756 3.34e-92 gerPC - - S ko:K06301 - ko00000 Spore germination protein
LHCGIODF_00757 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
LHCGIODF_00758 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
LHCGIODF_00759 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
LHCGIODF_00760 2.11e-219 cotH - - M ko:K06330 - ko00000 Spore Coat
LHCGIODF_00761 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LHCGIODF_00762 1.02e-74 yisL - - S - - - UPF0344 protein
LHCGIODF_00763 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LHCGIODF_00764 2.49e-130 yisN - - S - - - Protein of unknown function (DUF2777)
LHCGIODF_00765 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LHCGIODF_00766 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
LHCGIODF_00767 8.91e-189 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
LHCGIODF_00768 2.91e-310 yisQ - - V - - - Mate efflux family protein
LHCGIODF_00769 1.41e-207 yisR - - K - - - Transcriptional regulator
LHCGIODF_00770 3.04e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LHCGIODF_00771 1.73e-247 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LHCGIODF_00772 1.72e-120 yisT - - S - - - DinB family
LHCGIODF_00773 5.19e-138 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
LHCGIODF_00774 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LHCGIODF_00775 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
LHCGIODF_00776 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LHCGIODF_00777 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
LHCGIODF_00778 1.37e-295 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
LHCGIODF_00779 9.51e-185 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
LHCGIODF_00780 3.84e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
LHCGIODF_00781 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
LHCGIODF_00782 6.62e-140 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LHCGIODF_00783 6.13e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LHCGIODF_00784 8.28e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LHCGIODF_00785 2.39e-192 yitH - - K - - - Acetyltransferase (GNAT) domain
LHCGIODF_00786 8.44e-91 - - - S - - - Acetyltransferase (GNAT) domain
LHCGIODF_00787 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LHCGIODF_00788 4.29e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
LHCGIODF_00789 2.75e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
LHCGIODF_00790 4.16e-122 - - - - - - - -
LHCGIODF_00791 4.76e-217 - - - - - - - -
LHCGIODF_00792 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
LHCGIODF_00793 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
LHCGIODF_00794 5.02e-119 - - - - - - - -
LHCGIODF_00795 5.37e-58 yitR - - S - - - Domain of unknown function (DUF3784)
LHCGIODF_00796 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
LHCGIODF_00797 6.16e-200 yitS - - S - - - protein conserved in bacteria
LHCGIODF_00798 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LHCGIODF_00799 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
LHCGIODF_00800 4.11e-25 - - - S - - - Protein of unknown function (DUF3813)
LHCGIODF_00801 1.92e-08 - - - - - - - -
LHCGIODF_00802 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LHCGIODF_00803 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LHCGIODF_00804 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
LHCGIODF_00805 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
LHCGIODF_00806 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
LHCGIODF_00807 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
LHCGIODF_00808 7.41e-255 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LHCGIODF_00809 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LHCGIODF_00810 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
LHCGIODF_00811 1.69e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
LHCGIODF_00812 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LHCGIODF_00813 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
LHCGIODF_00814 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LHCGIODF_00815 2.51e-39 yjzC - - S - - - YjzC-like protein
LHCGIODF_00816 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
LHCGIODF_00817 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
LHCGIODF_00818 5.41e-134 yjaV - - - - - - -
LHCGIODF_00819 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
LHCGIODF_00820 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
LHCGIODF_00821 2.67e-38 yjzB - - - - - - -
LHCGIODF_00822 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LHCGIODF_00823 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LHCGIODF_00824 9.48e-193 yjaZ - - O - - - Zn-dependent protease
LHCGIODF_00825 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHCGIODF_00826 1.99e-235 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHCGIODF_00827 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
LHCGIODF_00828 3.73e-213 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHCGIODF_00829 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHCGIODF_00830 7.51e-189 yjbA - - S - - - Belongs to the UPF0736 family
LHCGIODF_00831 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
LHCGIODF_00832 1.49e-250 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LHCGIODF_00833 3.69e-144 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LHCGIODF_00834 4.89e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHCGIODF_00835 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHCGIODF_00836 1.12e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHCGIODF_00837 1.27e-219 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHCGIODF_00838 3.35e-260 yjbB - - EGP - - - Major Facilitator Superfamily
LHCGIODF_00839 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHCGIODF_00840 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LHCGIODF_00841 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
LHCGIODF_00842 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LHCGIODF_00843 4.7e-277 coiA - - S ko:K06198 - ko00000 Competence protein
LHCGIODF_00844 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LHCGIODF_00845 2.68e-28 - - - - - - - -
LHCGIODF_00846 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LHCGIODF_00847 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
LHCGIODF_00848 4.85e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LHCGIODF_00849 7.32e-130 yjbK - - S - - - protein conserved in bacteria
LHCGIODF_00850 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
LHCGIODF_00851 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
LHCGIODF_00852 4.17e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LHCGIODF_00853 4.28e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LHCGIODF_00854 6.65e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LHCGIODF_00855 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LHCGIODF_00856 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LHCGIODF_00857 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
LHCGIODF_00858 1.33e-276 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
LHCGIODF_00859 5.35e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
LHCGIODF_00860 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LHCGIODF_00861 1.52e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LHCGIODF_00862 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LHCGIODF_00863 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LHCGIODF_00864 1.47e-103 yjbX - - S - - - Spore coat protein
LHCGIODF_00865 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
LHCGIODF_00866 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
LHCGIODF_00867 3.55e-110 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
LHCGIODF_00868 1.08e-54 cotW - - - ko:K06341 - ko00000 -
LHCGIODF_00869 1.44e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
LHCGIODF_00870 3.03e-76 yjcA - - S - - - Protein of unknown function (DUF1360)
LHCGIODF_00873 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
LHCGIODF_00874 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LHCGIODF_00875 6.31e-51 - - - - - - - -
LHCGIODF_00876 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHCGIODF_00877 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
LHCGIODF_00878 1.91e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
LHCGIODF_00879 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LHCGIODF_00880 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LHCGIODF_00881 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
LHCGIODF_00882 1.05e-273 yjcL - - S - - - Protein of unknown function (DUF819)
LHCGIODF_00885 6.49e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
LHCGIODF_00886 4.52e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
LHCGIODF_00887 3.77e-12 - - - S - - - Helix-turn-helix domain
LHCGIODF_00888 4.17e-103 - - - - - - - -
LHCGIODF_00889 1.38e-66 - - - L - - - COG2963 Transposase and inactivated derivatives
LHCGIODF_00890 7.5e-80 - - - L ko:K07497 - ko00000 Integrase core domain
LHCGIODF_00891 3.71e-96 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LHCGIODF_00892 8.18e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
LHCGIODF_00893 5.35e-61 - - - K - - - Helix-turn-helix domain
LHCGIODF_00894 2.05e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LHCGIODF_00895 3.07e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LHCGIODF_00896 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LHCGIODF_00897 1.05e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LHCGIODF_00898 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LHCGIODF_00899 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LHCGIODF_00900 4.21e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LHCGIODF_00901 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LHCGIODF_00902 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LHCGIODF_00903 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
LHCGIODF_00904 8.41e-202 yloC - - S - - - stress-induced protein
LHCGIODF_00905 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
LHCGIODF_00906 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
LHCGIODF_00907 5.37e-107 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
LHCGIODF_00908 2.5e-188 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
LHCGIODF_00909 4.85e-184 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LHCGIODF_00910 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
LHCGIODF_00911 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
LHCGIODF_00912 1.41e-227 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
LHCGIODF_00913 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
LHCGIODF_00915 1.27e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LHCGIODF_00916 2.67e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LHCGIODF_00917 2.46e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LHCGIODF_00918 4.31e-182 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LHCGIODF_00919 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
LHCGIODF_00920 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LHCGIODF_00921 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LHCGIODF_00922 2.97e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LHCGIODF_00923 2.24e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
LHCGIODF_00924 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LHCGIODF_00925 8.3e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LHCGIODF_00926 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LHCGIODF_00927 2.63e-82 ylyA - - T - - - COG1734 DnaK suppressor protein
LHCGIODF_00928 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LHCGIODF_00929 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
LHCGIODF_00930 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
LHCGIODF_00931 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
LHCGIODF_00932 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LHCGIODF_00933 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LHCGIODF_00934 3.73e-203 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
LHCGIODF_00935 3.58e-51 ylmC - - S - - - sporulation protein
LHCGIODF_00936 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
LHCGIODF_00937 1.1e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LHCGIODF_00938 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHCGIODF_00939 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHCGIODF_00940 2.05e-218 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LHCGIODF_00941 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
LHCGIODF_00942 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LHCGIODF_00943 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LHCGIODF_00944 5.37e-76 sbp - - S - - - small basic protein
LHCGIODF_00945 1.5e-132 ylxX - - S - - - protein conserved in bacteria
LHCGIODF_00946 1.35e-143 ylxW - - S - - - protein conserved in bacteria
LHCGIODF_00947 3.37e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LHCGIODF_00948 3.74e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
LHCGIODF_00949 1.82e-255 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LHCGIODF_00950 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LHCGIODF_00951 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LHCGIODF_00952 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LHCGIODF_00953 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LHCGIODF_00954 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
LHCGIODF_00955 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LHCGIODF_00956 3.42e-68 ftsL - - D - - - Essential cell division protein
LHCGIODF_00957 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LHCGIODF_00958 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LHCGIODF_00959 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LHCGIODF_00960 5.34e-213 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LHCGIODF_00961 1.33e-115 ylbP - - K - - - n-acetyltransferase
LHCGIODF_00962 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LHCGIODF_00963 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LHCGIODF_00964 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
LHCGIODF_00966 7.11e-293 ylbM - - S - - - Belongs to the UPF0348 family
LHCGIODF_00967 2.24e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LHCGIODF_00968 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LHCGIODF_00969 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
LHCGIODF_00970 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LHCGIODF_00971 6.07e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
LHCGIODF_00972 4.36e-52 ylbG - - S - - - UPF0298 protein
LHCGIODF_00973 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
LHCGIODF_00974 1.73e-48 ylbE - - S - - - YlbE-like protein
LHCGIODF_00975 9.28e-89 ylbD - - S - - - Putative coat protein
LHCGIODF_00976 4.39e-256 ylbC - - S - - - protein with SCP PR1 domains
LHCGIODF_00977 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
LHCGIODF_00978 1.61e-81 ylbA - - S - - - YugN-like family
LHCGIODF_00979 1.21e-213 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
LHCGIODF_00980 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LHCGIODF_00981 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LHCGIODF_00982 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LHCGIODF_00983 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LHCGIODF_00984 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LHCGIODF_00985 2.85e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LHCGIODF_00986 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LHCGIODF_00987 7.05e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LHCGIODF_00988 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
LHCGIODF_00989 2.87e-218 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LHCGIODF_00990 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LHCGIODF_00991 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
LHCGIODF_00992 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LHCGIODF_00993 8.92e-44 ylaI - - S - - - protein conserved in bacteria
LHCGIODF_00994 4.4e-63 ylaH - - S - - - YlaH-like protein
LHCGIODF_00995 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LHCGIODF_00996 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
LHCGIODF_00997 1.74e-57 ylaE - - - - - - -
LHCGIODF_00999 3.56e-115 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHCGIODF_01000 1.44e-56 ylaB - - - - - - -
LHCGIODF_01001 0.0 ylaA - - - - - - -
LHCGIODF_01002 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
LHCGIODF_01003 7.08e-221 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LHCGIODF_01004 2.45e-99 ykzC - - S - - - Acetyltransferase (GNAT) family
LHCGIODF_01005 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
LHCGIODF_01006 4.48e-35 ykzI - - - - - - -
LHCGIODF_01007 1.25e-150 yktB - - S - - - Belongs to the UPF0637 family
LHCGIODF_01008 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
LHCGIODF_01009 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
LHCGIODF_01010 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
LHCGIODF_01011 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LHCGIODF_01012 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LHCGIODF_01013 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LHCGIODF_01014 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LHCGIODF_01015 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
LHCGIODF_01016 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LHCGIODF_01017 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LHCGIODF_01018 4.79e-186 ykrA - - S - - - hydrolases of the HAD superfamily
LHCGIODF_01019 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
LHCGIODF_01020 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LHCGIODF_01021 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LHCGIODF_01022 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LHCGIODF_01023 2.41e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
LHCGIODF_01024 2.65e-306 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LHCGIODF_01025 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
LHCGIODF_01026 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
LHCGIODF_01027 6.35e-18 - - - S - - - Uncharacterized protein YkpC
LHCGIODF_01028 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
LHCGIODF_01029 7.87e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LHCGIODF_01030 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LHCGIODF_01031 5.43e-52 ykoA - - - - - - -
LHCGIODF_01032 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LHCGIODF_01033 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LHCGIODF_01034 4.07e-215 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
LHCGIODF_01035 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_01036 1.11e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LHCGIODF_01037 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_01038 1.16e-233 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LHCGIODF_01039 5.97e-147 yknW - - S - - - Yip1 domain
LHCGIODF_01040 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LHCGIODF_01041 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LHCGIODF_01042 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LHCGIODF_01043 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
LHCGIODF_01044 1.99e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
LHCGIODF_01045 4.29e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
LHCGIODF_01046 2.54e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LHCGIODF_01047 2.17e-140 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LHCGIODF_01048 3.3e-198 yknT - - - ko:K06437 - ko00000 -
LHCGIODF_01049 1.78e-120 rok - - K - - - Repressor of ComK
LHCGIODF_01050 6.01e-104 ykuV - - CO - - - thiol-disulfide
LHCGIODF_01051 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
LHCGIODF_01052 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
LHCGIODF_01053 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
LHCGIODF_01054 1.27e-272 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LHCGIODF_01055 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LHCGIODF_01056 1.2e-100 fld - - C ko:K03839 - ko00000 Flavodoxin
LHCGIODF_01057 1.18e-220 ykuO - - - - - - -
LHCGIODF_01058 1.44e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
LHCGIODF_01059 6.52e-216 ccpC - - K - - - Transcriptional regulator
LHCGIODF_01060 5.15e-100 ykuL - - S - - - CBS domain
LHCGIODF_01061 7.83e-38 ykzF - - S - - - Antirepressor AbbA
LHCGIODF_01062 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
LHCGIODF_01063 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
LHCGIODF_01064 7.16e-298 ykuI - - T - - - Diguanylate phosphodiesterase
LHCGIODF_01065 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHCGIODF_01066 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
LHCGIODF_01067 5.84e-115 ykuD - - S - - - protein conserved in bacteria
LHCGIODF_01068 3.62e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LHCGIODF_01069 7.49e-110 ykyB - - S - - - YkyB-like protein
LHCGIODF_01070 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
LHCGIODF_01071 1.05e-22 - - - - - - - -
LHCGIODF_01072 3.44e-282 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LHCGIODF_01073 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_01074 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LHCGIODF_01075 1.04e-169 ykwD - - J - - - protein with SCP PR1 domains
LHCGIODF_01076 1.68e-17 vgb - - H ko:K18235 - ko00000,ko01000,ko01504 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
LHCGIODF_01077 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LHCGIODF_01078 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHCGIODF_01079 4.2e-160 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHCGIODF_01080 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
LHCGIODF_01081 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_01082 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LHCGIODF_01083 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
LHCGIODF_01084 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHCGIODF_01085 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
LHCGIODF_01087 5.43e-229 ykvZ - - K - - - Transcriptional regulator
LHCGIODF_01089 1.93e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LHCGIODF_01090 3.99e-09 - - - - - - - -
LHCGIODF_01091 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LHCGIODF_01092 5.79e-117 stoA - - CO - - - thiol-disulfide
LHCGIODF_01093 9.18e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LHCGIODF_01094 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
LHCGIODF_01095 2.5e-39 - - - - - - - -
LHCGIODF_01096 5.43e-35 ykvS - - S - - - protein conserved in bacteria
LHCGIODF_01097 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
LHCGIODF_01098 7.68e-172 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LHCGIODF_01099 2.8e-81 ykvN - - K - - - Transcriptional regulator
LHCGIODF_01100 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LHCGIODF_01101 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LHCGIODF_01102 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
LHCGIODF_01103 6.42e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LHCGIODF_01104 3.35e-227 ykvI - - S - - - membrane
LHCGIODF_01105 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
LHCGIODF_01106 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LHCGIODF_01107 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LHCGIODF_01108 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
LHCGIODF_01109 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LHCGIODF_01110 5.84e-95 eag - - - - - - -
LHCGIODF_01112 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
LHCGIODF_01113 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LHCGIODF_01114 4.34e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LHCGIODF_01115 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LHCGIODF_01116 9.72e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LHCGIODF_01117 1.96e-295 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LHCGIODF_01118 4.7e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LHCGIODF_01119 1.43e-292 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LHCGIODF_01120 3.8e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LHCGIODF_01122 4.58e-114 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LHCGIODF_01123 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_01124 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
LHCGIODF_01125 1.77e-28 ykzE - - - - - - -
LHCGIODF_01127 2.58e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
LHCGIODF_01128 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LHCGIODF_01129 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
LHCGIODF_01130 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
LHCGIODF_01131 9.93e-200 rsgI - - S - - - Anti-sigma factor N-terminus
LHCGIODF_01132 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHCGIODF_01133 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LHCGIODF_01134 1.71e-143 ykoX - - S - - - membrane-associated protein
LHCGIODF_01135 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
LHCGIODF_01136 5.94e-203 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LHCGIODF_01137 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
LHCGIODF_01138 3.17e-236 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
LHCGIODF_01139 0.0 ykoS - - - - - - -
LHCGIODF_01140 1.77e-197 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
LHCGIODF_01141 2.38e-127 ykoP - - G - - - polysaccharide deacetylase
LHCGIODF_01142 3.68e-275 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
LHCGIODF_01143 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
LHCGIODF_01144 2.51e-35 ykoL - - - - - - -
LHCGIODF_01145 3.3e-25 - - - - - - - -
LHCGIODF_01146 1.49e-70 tnrA - - K - - - transcriptional
LHCGIODF_01147 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
LHCGIODF_01149 1.45e-08 - - - - - - - -
LHCGIODF_01150 5.28e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
LHCGIODF_01151 9.6e-146 ykoI - - S - - - Peptidase propeptide and YPEB domain
LHCGIODF_01152 1.42e-305 ykoH - - T - - - Histidine kinase
LHCGIODF_01153 1.01e-157 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHCGIODF_01154 3.73e-137 ykoF - - S - - - YKOF-related Family
LHCGIODF_01155 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
LHCGIODF_01156 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_01157 7.36e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
LHCGIODF_01158 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LHCGIODF_01159 8.62e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LHCGIODF_01160 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LHCGIODF_01161 1.9e-113 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
LHCGIODF_01162 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
LHCGIODF_01163 2.86e-97 ohrR - - K - - - COG1846 Transcriptional regulators
LHCGIODF_01164 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
LHCGIODF_01165 1.32e-288 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LHCGIODF_01166 4.3e-255 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LHCGIODF_01167 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LHCGIODF_01168 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
LHCGIODF_01169 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
LHCGIODF_01170 2.43e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LHCGIODF_01171 6.42e-128 ykkA - - S - - - Protein of unknown function (DUF664)
LHCGIODF_01172 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
LHCGIODF_01173 2.11e-16 - - - - - - - -
LHCGIODF_01174 1.26e-287 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LHCGIODF_01175 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
LHCGIODF_01176 1.78e-205 ykgA - - E - - - Amidinotransferase
LHCGIODF_01177 3.16e-258 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
LHCGIODF_01178 8.09e-235 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHCGIODF_01179 1.78e-210 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LHCGIODF_01180 1.55e-253 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LHCGIODF_01181 2.64e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
LHCGIODF_01183 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LHCGIODF_01184 1.29e-234 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHCGIODF_01185 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHCGIODF_01186 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHCGIODF_01187 1.15e-195 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
LHCGIODF_01188 3.2e-176 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
LHCGIODF_01189 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LHCGIODF_01191 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LHCGIODF_01192 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LHCGIODF_01194 1.9e-231 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LHCGIODF_01195 2.57e-309 steT - - E ko:K03294 - ko00000 amino acid
LHCGIODF_01196 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
LHCGIODF_01197 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
LHCGIODF_01198 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
LHCGIODF_01199 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
LHCGIODF_01200 5.76e-212 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
LHCGIODF_01201 8.12e-53 xhlB - - S - - - SPP1 phage holin
LHCGIODF_01202 7.71e-52 xhlA - - S - - - Haemolysin XhlA
LHCGIODF_01203 6.16e-198 xepA - - - - - - -
LHCGIODF_01204 1.1e-31 xkdX - - - - - - -
LHCGIODF_01205 5.66e-70 xkdW - - S - - - XkdW protein
LHCGIODF_01206 0.0 - - - - - - - -
LHCGIODF_01207 4.43e-56 - - - - - - - -
LHCGIODF_01208 6.51e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
LHCGIODF_01209 1.26e-243 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LHCGIODF_01210 3.82e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
LHCGIODF_01211 1.45e-51 xkdR - - S - - - Protein of unknown function (DUF2577)
LHCGIODF_01212 2.31e-232 xkdQ - - G - - - NLP P60 protein
LHCGIODF_01213 4.25e-152 xkdP - - S - - - Lysin motif
LHCGIODF_01214 0.0 xkdO - - L - - - Transglycosylase SLT domain
LHCGIODF_01215 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
LHCGIODF_01216 6.01e-99 xkdM - - S - - - Phage tail tube protein
LHCGIODF_01217 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
LHCGIODF_01218 2.87e-101 xkdJ - - - - - - -
LHCGIODF_01219 2.38e-114 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
LHCGIODF_01220 2.91e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
LHCGIODF_01221 6.64e-82 yqbG - - S - - - Protein of unknown function (DUF3199)
LHCGIODF_01222 3.91e-217 xkdG - - S - - - Phage capsid family
LHCGIODF_01223 1.4e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
LHCGIODF_01224 0.0 yqbA - - S - - - portal protein
LHCGIODF_01225 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
LHCGIODF_01226 4.58e-177 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
LHCGIODF_01227 8.12e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LHCGIODF_01231 7.48e-153 xkdC - - L - - - Bacterial dnaA protein
LHCGIODF_01232 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
LHCGIODF_01234 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
LHCGIODF_01235 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
LHCGIODF_01236 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
LHCGIODF_01237 1.3e-137 yjqB - - S - - - Pfam:DUF867
LHCGIODF_01238 1.35e-80 yjqA - - S - - - Bacterial PH domain
LHCGIODF_01239 5.34e-218 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LHCGIODF_01240 1.79e-55 - - - S - - - YCII-related domain
LHCGIODF_01242 7.06e-271 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LHCGIODF_01243 1.23e-313 VCP - - O - - - AAA domain (dynein-related subfamily)
LHCGIODF_01244 2.71e-103 yjoA - - S - - - DinB family
LHCGIODF_01245 1.31e-166 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
LHCGIODF_01246 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
LHCGIODF_01247 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
LHCGIODF_01248 6.95e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
LHCGIODF_01249 1.08e-286 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
LHCGIODF_01250 2.23e-195 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LHCGIODF_01251 1.08e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
LHCGIODF_01252 1.86e-245 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
LHCGIODF_01253 1.2e-240 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
LHCGIODF_01254 1.19e-311 - - - G ko:K03292 - ko00000 symporter YjmB
LHCGIODF_01255 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
LHCGIODF_01256 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LHCGIODF_01257 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
LHCGIODF_01258 2.36e-116 yjlB - - S - - - Cupin domain
LHCGIODF_01259 8.95e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
LHCGIODF_01260 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LHCGIODF_01261 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
LHCGIODF_01262 8.69e-189 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LHCGIODF_01263 1.11e-41 - - - - - - - -
LHCGIODF_01264 1.19e-277 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LHCGIODF_01265 1.16e-286 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LHCGIODF_01267 1.45e-144 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LHCGIODF_01269 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
LHCGIODF_01270 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
LHCGIODF_01271 5.79e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
LHCGIODF_01272 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
LHCGIODF_01273 1.36e-211 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
LHCGIODF_01274 1.13e-29 yjfB - - S - - - Putative motility protein
LHCGIODF_01275 8.68e-106 - - - S - - - Protein of unknown function (DUF2690)
LHCGIODF_01276 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
LHCGIODF_01278 5.08e-222 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LHCGIODF_01279 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
LHCGIODF_01280 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
LHCGIODF_01281 8.3e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LHCGIODF_01283 1.47e-116 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LHCGIODF_01284 7.58e-75 yjdF3 - - S - - - Protein of unknown function (DUF2992)
LHCGIODF_01285 3.58e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LHCGIODF_01286 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHCGIODF_01287 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
LHCGIODF_01288 8.47e-59 yjcN - - - - - - -
LHCGIODF_01289 2.59e-22 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
LHCGIODF_01290 4.48e-23 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
LHCGIODF_01291 2.49e-07 - - - - - - - -
LHCGIODF_01292 2.28e-25 - - - - - - - -
LHCGIODF_01293 1.92e-47 - - - - - - - -
LHCGIODF_01297 2.51e-19 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_01299 6.79e-11 - - - S - - - Family of unknown function (DUF5316)
LHCGIODF_01301 1.8e-87 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LHCGIODF_01302 2.27e-104 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LHCGIODF_01303 2.83e-198 - - - M - - - nucleic acid phosphodiester bond hydrolysis
LHCGIODF_01304 2.15e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
LHCGIODF_01305 1.12e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LHCGIODF_01306 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHCGIODF_01307 2.77e-316 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_01308 3.06e-204 yuxN - - K - - - Transcriptional regulator
LHCGIODF_01309 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LHCGIODF_01310 2.6e-33 - - - S - - - Protein of unknown function (DUF3970)
LHCGIODF_01311 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LHCGIODF_01312 9.28e-250 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LHCGIODF_01313 1.76e-242 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
LHCGIODF_01314 6.34e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHCGIODF_01315 2.25e-243 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_01316 2.1e-161 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
LHCGIODF_01317 5.74e-172 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
LHCGIODF_01318 9.94e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LHCGIODF_01319 4.68e-79 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
LHCGIODF_01320 6.23e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LHCGIODF_01321 8.2e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
LHCGIODF_01322 2.12e-308 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LHCGIODF_01323 7.4e-234 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHCGIODF_01324 1.36e-214 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
LHCGIODF_01325 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LHCGIODF_01326 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
LHCGIODF_01327 0.0 yvrG - - T - - - Histidine kinase
LHCGIODF_01328 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHCGIODF_01329 6.16e-33 - - - - - - - -
LHCGIODF_01330 4.06e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
LHCGIODF_01331 3.46e-26 - - - S - - - YvrJ protein family
LHCGIODF_01332 2.17e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LHCGIODF_01333 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
LHCGIODF_01334 7.7e-273 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LHCGIODF_01335 1.09e-157 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_01336 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
LHCGIODF_01337 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LHCGIODF_01338 3.22e-224 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHCGIODF_01339 1.72e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHCGIODF_01340 3.13e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHCGIODF_01342 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
LHCGIODF_01343 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
LHCGIODF_01344 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
LHCGIODF_01345 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
LHCGIODF_01346 4.91e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
LHCGIODF_01347 1.22e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
LHCGIODF_01348 1.43e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
LHCGIODF_01349 1.77e-200 yvgN - - S - - - reductase
LHCGIODF_01350 9.32e-112 yvgO - - - - - - -
LHCGIODF_01351 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
LHCGIODF_01352 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LHCGIODF_01353 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LHCGIODF_01354 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LHCGIODF_01356 2.34e-139 yvgT - - S - - - membrane
LHCGIODF_01357 5.7e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
LHCGIODF_01358 3.45e-137 bdbD - - O - - - Thioredoxin
LHCGIODF_01359 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LHCGIODF_01360 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LHCGIODF_01361 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
LHCGIODF_01362 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
LHCGIODF_01363 2.95e-249 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LHCGIODF_01364 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LHCGIODF_01365 0.0 - - - S - - - Fusaric acid resistance protein-like
LHCGIODF_01366 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
LHCGIODF_01367 2.38e-69 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
LHCGIODF_01368 5.77e-127 - - - K - - - Bacterial regulatory proteins, tetR family
LHCGIODF_01369 2.01e-140 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHCGIODF_01370 1.07e-29 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHCGIODF_01371 4.89e-22 - - - - - - - -
LHCGIODF_01374 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LHCGIODF_01375 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LHCGIODF_01376 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
LHCGIODF_01377 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
LHCGIODF_01378 8.14e-196 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
LHCGIODF_01379 4.9e-48 yvzC - - K - - - transcriptional
LHCGIODF_01380 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
LHCGIODF_01381 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
LHCGIODF_01382 3.85e-72 yvaP - - K - - - transcriptional
LHCGIODF_01383 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHCGIODF_01384 2.54e-195 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
LHCGIODF_01385 1.41e-135 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
LHCGIODF_01386 2.99e-103 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LHCGIODF_01387 1.67e-110 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LHCGIODF_01388 7.1e-131 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_01391 1.18e-97 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
LHCGIODF_01392 8.57e-193 - - - V ko:K06147,ko:K06148,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
LHCGIODF_01393 1.04e-231 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
LHCGIODF_01394 2.48e-134 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LHCGIODF_01395 2.27e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LHCGIODF_01396 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LHCGIODF_01397 2.02e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LHCGIODF_01398 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LHCGIODF_01399 5.59e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LHCGIODF_01400 7.4e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LHCGIODF_01401 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LHCGIODF_01402 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LHCGIODF_01403 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LHCGIODF_01404 9.68e-136 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
LHCGIODF_01405 2.96e-145 yvbH - - S - - - YvbH-like oligomerisation region
LHCGIODF_01406 1.13e-156 yvbI - - M - - - Membrane
LHCGIODF_01407 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LHCGIODF_01408 9.77e-106 yvbK - - K - - - acetyltransferase
LHCGIODF_01409 3.94e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LHCGIODF_01410 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
LHCGIODF_01411 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LHCGIODF_01412 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LHCGIODF_01413 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LHCGIODF_01414 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LHCGIODF_01415 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHCGIODF_01416 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
LHCGIODF_01417 1.21e-244 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHCGIODF_01418 4.9e-206 yvbU - - K - - - Transcriptional regulator
LHCGIODF_01419 2.27e-197 yvbV - - EG - - - EamA-like transporter family
LHCGIODF_01420 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LHCGIODF_01421 7.05e-248 - - - S - - - Glycosyl hydrolase
LHCGIODF_01422 8.37e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LHCGIODF_01423 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LHCGIODF_01424 9.08e-175 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LHCGIODF_01425 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHCGIODF_01426 1.8e-250 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_01427 2.04e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LHCGIODF_01428 1.5e-202 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
LHCGIODF_01430 2.08e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
LHCGIODF_01431 2.51e-264 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
LHCGIODF_01432 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
LHCGIODF_01433 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
LHCGIODF_01434 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
LHCGIODF_01435 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
LHCGIODF_01436 4.62e-292 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
LHCGIODF_01437 2.72e-234 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_01438 2.79e-145 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
LHCGIODF_01439 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LHCGIODF_01440 6.75e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LHCGIODF_01441 5.69e-44 yvfG - - S - - - YvfG protein
LHCGIODF_01442 1.1e-233 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
LHCGIODF_01443 1.76e-277 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
LHCGIODF_01444 1.22e-82 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LHCGIODF_01445 9.14e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LHCGIODF_01446 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LHCGIODF_01447 6.76e-246 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LHCGIODF_01448 7.76e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
LHCGIODF_01449 6.04e-249 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LHCGIODF_01450 8.82e-265 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
LHCGIODF_01451 7.49e-280 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LHCGIODF_01452 1.25e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
LHCGIODF_01453 1.28e-213 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
LHCGIODF_01454 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LHCGIODF_01455 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LHCGIODF_01456 1.61e-157 epsA - - M ko:K19420 - ko00000 biosynthesis protein
LHCGIODF_01457 1.24e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
LHCGIODF_01458 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
LHCGIODF_01460 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
LHCGIODF_01461 1.75e-93 - - - S - - - Protein of unknown function (DUF3237)
LHCGIODF_01462 2.06e-161 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LHCGIODF_01463 0.0 pbpE - - V - - - Beta-lactamase
LHCGIODF_01464 7.19e-86 - - - - - - - -
LHCGIODF_01465 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
LHCGIODF_01466 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
LHCGIODF_01467 0.0 ybeC - - E - - - amino acid
LHCGIODF_01468 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
LHCGIODF_01469 1.49e-66 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LHCGIODF_01470 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
LHCGIODF_01471 1.12e-121 yvdQ - - S - - - Protein of unknown function (DUF3231)
LHCGIODF_01473 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LHCGIODF_01474 2.27e-148 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LHCGIODF_01475 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LHCGIODF_01476 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
LHCGIODF_01477 5.26e-202 malA - - S - - - Protein of unknown function (DUF1189)
LHCGIODF_01478 6.84e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
LHCGIODF_01479 3.37e-308 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
LHCGIODF_01480 4.02e-300 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
LHCGIODF_01481 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
LHCGIODF_01482 1.54e-221 yvdE - - K - - - Transcriptional regulator
LHCGIODF_01483 6.28e-136 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
LHCGIODF_01484 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
LHCGIODF_01485 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LHCGIODF_01486 8.79e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LHCGIODF_01487 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LHCGIODF_01488 9.56e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
LHCGIODF_01489 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
LHCGIODF_01490 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
LHCGIODF_01491 9.16e-203 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LHCGIODF_01492 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
LHCGIODF_01493 1.29e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHCGIODF_01494 5.53e-62 yxlC - - S - - - Family of unknown function (DUF5345)
LHCGIODF_01495 1.63e-39 - - - - - - - -
LHCGIODF_01496 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
LHCGIODF_01497 8.18e-211 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_01498 9.33e-178 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LHCGIODF_01499 1.95e-271 yxlH - - EGP - - - Major Facilitator Superfamily
LHCGIODF_01500 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LHCGIODF_01501 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LHCGIODF_01502 8.94e-28 yxzF - - - - - - -
LHCGIODF_01503 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
LHCGIODF_01504 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
LHCGIODF_01505 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHCGIODF_01506 1.3e-49 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHCGIODF_01507 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LHCGIODF_01508 1.77e-262 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LHCGIODF_01509 2.91e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHCGIODF_01510 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LHCGIODF_01511 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHCGIODF_01512 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
LHCGIODF_01513 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHCGIODF_01514 5.1e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
LHCGIODF_01515 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
LHCGIODF_01516 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
LHCGIODF_01517 8.66e-295 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LHCGIODF_01518 1.25e-114 ywaE - - K - - - Transcriptional regulator
LHCGIODF_01519 8.81e-152 ywaF - - S - - - Integral membrane protein
LHCGIODF_01520 6.53e-217 gspA - - M - - - General stress
LHCGIODF_01521 9.07e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LHCGIODF_01522 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHCGIODF_01523 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LHCGIODF_01524 1.22e-309 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHCGIODF_01525 3.56e-161 ywbB - - S - - - Protein of unknown function (DUF2711)
LHCGIODF_01526 4.01e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
LHCGIODF_01527 1.15e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
LHCGIODF_01528 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
LHCGIODF_01529 1.29e-280 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
LHCGIODF_01530 1.21e-143 ywbG - - M - - - effector of murein hydrolase
LHCGIODF_01531 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LHCGIODF_01532 2.7e-203 ywbI - - K - - - Transcriptional regulator
LHCGIODF_01533 6.56e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LHCGIODF_01534 2.57e-148 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LHCGIODF_01535 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
LHCGIODF_01536 4.87e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
LHCGIODF_01537 1.26e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
LHCGIODF_01538 7.65e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LHCGIODF_01539 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LHCGIODF_01540 1.23e-63 ywcB - - S - - - Protein of unknown function, DUF485
LHCGIODF_01542 2.41e-158 ywcC - - K - - - transcriptional regulator
LHCGIODF_01543 3.33e-77 gtcA - - S - - - GtrA-like protein
LHCGIODF_01544 5.56e-291 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LHCGIODF_01545 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LHCGIODF_01546 5.11e-49 ydaS - - S - - - membrane
LHCGIODF_01547 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LHCGIODF_01548 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LHCGIODF_01549 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LHCGIODF_01550 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LHCGIODF_01551 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
LHCGIODF_01552 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LHCGIODF_01553 1.98e-179 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
LHCGIODF_01554 4.19e-239 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHCGIODF_01555 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LHCGIODF_01557 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LHCGIODF_01558 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
LHCGIODF_01559 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHCGIODF_01560 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LHCGIODF_01561 6.19e-39 ywdA - - - - - - -
LHCGIODF_01562 6.07e-185 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LHCGIODF_01563 3.84e-191 ywdF - - S - - - Glycosyltransferase like family 2
LHCGIODF_01564 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LHCGIODF_01565 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LHCGIODF_01566 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
LHCGIODF_01567 1.86e-303 ywdJ - - F - - - Xanthine uracil
LHCGIODF_01568 1.59e-78 ywdK - - S - - - small membrane protein
LHCGIODF_01569 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LHCGIODF_01570 8.08e-187 spsA - - M - - - Spore Coat
LHCGIODF_01571 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
LHCGIODF_01572 3.73e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
LHCGIODF_01573 4.22e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
LHCGIODF_01574 2.27e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
LHCGIODF_01575 1.23e-164 spsF - - M ko:K07257 - ko00000 Spore Coat
LHCGIODF_01576 5.26e-236 spsG - - M - - - Spore Coat
LHCGIODF_01577 6.13e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LHCGIODF_01578 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LHCGIODF_01579 2.44e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LHCGIODF_01580 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
LHCGIODF_01581 1.51e-100 - - - - - - - -
LHCGIODF_01582 6.05e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LHCGIODF_01583 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LHCGIODF_01584 0.0 rocB - - E - - - arginine degradation protein
LHCGIODF_01585 8.84e-317 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LHCGIODF_01586 4.44e-274 ywfA - - EGP - - - -transporter
LHCGIODF_01587 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LHCGIODF_01588 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LHCGIODF_01589 3.14e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHCGIODF_01590 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LHCGIODF_01591 3.74e-266 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
LHCGIODF_01592 2.21e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
LHCGIODF_01593 2.37e-176 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
LHCGIODF_01594 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
LHCGIODF_01595 1.37e-223 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
LHCGIODF_01596 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_01597 1.77e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LHCGIODF_01598 3.8e-196 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
LHCGIODF_01599 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
LHCGIODF_01600 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
LHCGIODF_01601 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
LHCGIODF_01602 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
LHCGIODF_01603 4.3e-101 yffB - - K - - - Transcriptional regulator
LHCGIODF_01604 1.15e-301 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
LHCGIODF_01606 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LHCGIODF_01607 1.45e-93 ywhA - - K - - - Transcriptional regulator
LHCGIODF_01608 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
LHCGIODF_01609 3.29e-154 ywhC - - S - - - Peptidase family M50
LHCGIODF_01610 9.14e-122 ywhD - - S - - - YwhD family
LHCGIODF_01611 1.21e-63 - - - - - - - -
LHCGIODF_01612 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LHCGIODF_01613 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LHCGIODF_01614 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LHCGIODF_01615 1.09e-32 - - - S - - - Aminoacyl-tRNA editing domain
LHCGIODF_01617 9.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LHCGIODF_01618 3.67e-272 ywhK - - CO - - - amine dehydrogenase activity
LHCGIODF_01620 1.09e-313 - - - L - - - Peptidase, M16
LHCGIODF_01621 1.7e-276 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
LHCGIODF_01622 5.92e-298 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
LHCGIODF_01623 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LHCGIODF_01625 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
LHCGIODF_01626 3.71e-12 - - - S - - - Bacteriocin subtilosin A
LHCGIODF_01627 4.64e-96 ywiB - - S - - - protein conserved in bacteria
LHCGIODF_01628 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LHCGIODF_01629 1.2e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LHCGIODF_01630 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
LHCGIODF_01631 1.84e-179 ywiC - - S - - - YwiC-like protein
LHCGIODF_01632 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
LHCGIODF_01633 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LHCGIODF_01634 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
LHCGIODF_01635 2.28e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
LHCGIODF_01636 2.06e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
LHCGIODF_01637 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LHCGIODF_01638 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
LHCGIODF_01639 2.08e-117 ywjB - - H - - - RibD C-terminal domain
LHCGIODF_01640 1.32e-57 ywjC - - - - - - -
LHCGIODF_01641 6.65e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LHCGIODF_01642 1.42e-288 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LHCGIODF_01643 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
LHCGIODF_01644 2.98e-269 acdA - - I - - - acyl-CoA dehydrogenase
LHCGIODF_01645 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LHCGIODF_01646 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LHCGIODF_01647 3.86e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
LHCGIODF_01648 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
LHCGIODF_01649 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
LHCGIODF_01650 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LHCGIODF_01651 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LHCGIODF_01652 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
LHCGIODF_01653 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LHCGIODF_01654 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
LHCGIODF_01655 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LHCGIODF_01656 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LHCGIODF_01657 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LHCGIODF_01659 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHCGIODF_01660 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
LHCGIODF_01661 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
LHCGIODF_01662 2.15e-63 ytpI - - S - - - YtpI-like protein
LHCGIODF_01663 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
LHCGIODF_01664 1.15e-39 - - - - - - - -
LHCGIODF_01665 5.12e-112 ytrI - - - - - - -
LHCGIODF_01666 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
LHCGIODF_01667 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LHCGIODF_01668 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LHCGIODF_01669 8.83e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LHCGIODF_01670 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LHCGIODF_01671 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LHCGIODF_01672 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LHCGIODF_01673 3.16e-80 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
LHCGIODF_01674 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
LHCGIODF_01675 9.38e-95 ytwI - - S - - - membrane
LHCGIODF_01676 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LHCGIODF_01677 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
LHCGIODF_01678 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
LHCGIODF_01679 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHCGIODF_01680 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
LHCGIODF_01681 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LHCGIODF_01682 4.05e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LHCGIODF_01683 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
LHCGIODF_01684 4e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LHCGIODF_01685 4.54e-205 ytbE - - S - - - reductase
LHCGIODF_01686 5.2e-258 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
LHCGIODF_01687 1.15e-86 ytcD - - K - - - Transcriptional regulator
LHCGIODF_01688 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LHCGIODF_01689 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LHCGIODF_01690 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LHCGIODF_01691 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
LHCGIODF_01692 1e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LHCGIODF_01693 1.33e-141 ytxB - - S - - - SNARE associated Golgi protein
LHCGIODF_01694 3.46e-205 ytxC - - S - - - YtxC-like family
LHCGIODF_01696 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LHCGIODF_01697 1.98e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
LHCGIODF_01698 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_01699 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
LHCGIODF_01700 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LHCGIODF_01701 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LHCGIODF_01703 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LHCGIODF_01704 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LHCGIODF_01705 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LHCGIODF_01706 3.65e-59 ysdA - - S - - - Membrane
LHCGIODF_01707 3.26e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
LHCGIODF_01708 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
LHCGIODF_01709 9.92e-242 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LHCGIODF_01710 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
LHCGIODF_01711 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
LHCGIODF_01712 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LHCGIODF_01713 1.67e-184 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
LHCGIODF_01714 7.5e-282 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LHCGIODF_01715 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
LHCGIODF_01716 1.94e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
LHCGIODF_01717 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
LHCGIODF_01718 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
LHCGIODF_01719 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
LHCGIODF_01720 2.07e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
LHCGIODF_01721 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
LHCGIODF_01722 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
LHCGIODF_01723 1.45e-259 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
LHCGIODF_01724 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
LHCGIODF_01725 1.81e-170 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHCGIODF_01726 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LHCGIODF_01727 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LHCGIODF_01728 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LHCGIODF_01729 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LHCGIODF_01730 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
LHCGIODF_01731 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
LHCGIODF_01732 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LHCGIODF_01733 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
LHCGIODF_01734 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LHCGIODF_01735 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_01736 1.81e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
LHCGIODF_01737 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
LHCGIODF_01738 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
LHCGIODF_01739 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
LHCGIODF_01740 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LHCGIODF_01741 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LHCGIODF_01742 6.56e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LHCGIODF_01743 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
LHCGIODF_01744 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
LHCGIODF_01745 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LHCGIODF_01746 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LHCGIODF_01747 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
LHCGIODF_01748 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_01749 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHCGIODF_01750 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LHCGIODF_01751 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
LHCGIODF_01752 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LHCGIODF_01753 7.86e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LHCGIODF_01754 1.65e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
LHCGIODF_01756 6.77e-181 ysnF - - S - - - protein conserved in bacteria
LHCGIODF_01757 1.55e-44 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
LHCGIODF_01759 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LHCGIODF_01760 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LHCGIODF_01761 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LHCGIODF_01762 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LHCGIODF_01763 8.67e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LHCGIODF_01764 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LHCGIODF_01765 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LHCGIODF_01766 3.19e-239 ysoA - - H - - - Tetratricopeptide repeat
LHCGIODF_01767 2.54e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LHCGIODF_01768 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LHCGIODF_01769 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
LHCGIODF_01770 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LHCGIODF_01771 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LHCGIODF_01772 4.77e-116 ysxD - - - - - - -
LHCGIODF_01773 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LHCGIODF_01774 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
LHCGIODF_01775 8.91e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LHCGIODF_01776 1.23e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LHCGIODF_01777 3.7e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
LHCGIODF_01778 3.53e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LHCGIODF_01779 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
LHCGIODF_01780 2.79e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LHCGIODF_01781 1.53e-35 - - - - - - - -
LHCGIODF_01782 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LHCGIODF_01783 1.83e-314 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LHCGIODF_01784 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LHCGIODF_01785 3.91e-207 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
LHCGIODF_01786 1.66e-130 maf - - D ko:K06287 - ko00000 septum formation protein Maf
LHCGIODF_01787 5.54e-86 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
LHCGIODF_01788 1.77e-291 - - - S - - - Recombinase
LHCGIODF_01789 2.85e-93 - - - S - - - Pfam:Peptidase_M78
LHCGIODF_01790 8.53e-84 - - - S - - - sequence-specific DNA binding
LHCGIODF_01791 6.56e-12 - - - K - - - helix-turn-helix
LHCGIODF_01794 1.01e-63 - - - - - - - -
LHCGIODF_01795 1.04e-14 - - - - - - - -
LHCGIODF_01796 3.86e-209 - - - L - - - Protein of unknown function (DUF2800)
LHCGIODF_01797 1.57e-114 - - - S - - - Protein of unknown function (DUF2815)
LHCGIODF_01798 1.07e-05 - - - - - - - -
LHCGIODF_01799 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase A domain
LHCGIODF_01802 0.0 - - - L - - - Virulence-associated protein E
LHCGIODF_01819 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LHCGIODF_01820 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LHCGIODF_01821 3.72e-238 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
LHCGIODF_01822 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
LHCGIODF_01823 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LHCGIODF_01824 8.04e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
LHCGIODF_01825 2.59e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
LHCGIODF_01826 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
LHCGIODF_01827 2.82e-262 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
LHCGIODF_01829 6.86e-296 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
LHCGIODF_01830 5.23e-229 ytcB - - M - - - NAD-dependent epimerase dehydratase
LHCGIODF_01831 7.94e-308 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LHCGIODF_01832 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
LHCGIODF_01833 3.53e-168 yteA - - T - - - COG1734 DnaK suppressor protein
LHCGIODF_01834 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LHCGIODF_01835 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LHCGIODF_01836 6.65e-195 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LHCGIODF_01837 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LHCGIODF_01838 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LHCGIODF_01839 5.81e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LHCGIODF_01840 1.79e-215 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LHCGIODF_01841 1.97e-175 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LHCGIODF_01842 4.31e-295 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LHCGIODF_01843 9.24e-192 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
LHCGIODF_01844 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
LHCGIODF_01845 1.15e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LHCGIODF_01846 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LHCGIODF_01847 1.44e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LHCGIODF_01848 1.27e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LHCGIODF_01849 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LHCGIODF_01850 4.78e-95 ytkA - - S - - - YtkA-like
LHCGIODF_01852 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LHCGIODF_01853 3.2e-81 ytkC - - S - - - Bacteriophage holin family
LHCGIODF_01854 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LHCGIODF_01855 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LHCGIODF_01856 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LHCGIODF_01857 1.87e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LHCGIODF_01858 5.48e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LHCGIODF_01859 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
LHCGIODF_01860 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LHCGIODF_01861 1.86e-285 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LHCGIODF_01862 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LHCGIODF_01863 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LHCGIODF_01864 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LHCGIODF_01865 4.7e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
LHCGIODF_01866 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
LHCGIODF_01867 1.17e-133 ytqB - - J - - - Putative rRNA methylase
LHCGIODF_01868 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
LHCGIODF_01869 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
LHCGIODF_01871 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
LHCGIODF_01872 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_01873 1.98e-214 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LHCGIODF_01874 4.77e-193 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
LHCGIODF_01875 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_01876 1.39e-296 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LHCGIODF_01877 1.7e-165 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHCGIODF_01878 6.9e-234 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
LHCGIODF_01879 1.56e-178 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_01880 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
LHCGIODF_01881 2.67e-76 yttA - - S - - - Pfam Transposase IS66
LHCGIODF_01882 2.45e-268 yttB - - EGP - - - Major facilitator superfamily
LHCGIODF_01883 1.56e-182 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LHCGIODF_01884 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
LHCGIODF_01885 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LHCGIODF_01886 4.98e-68 ytwF - - P - - - Sulfurtransferase
LHCGIODF_01887 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
LHCGIODF_01888 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LHCGIODF_01889 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHCGIODF_01890 8.99e-313 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LHCGIODF_01891 1.31e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_01892 2.66e-218 - - - S - - - Acetyl xylan esterase (AXE1)
LHCGIODF_01893 7.51e-178 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LHCGIODF_01894 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LHCGIODF_01895 2.58e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LHCGIODF_01896 2.68e-159 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LHCGIODF_01897 1.46e-240 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LHCGIODF_01898 3.75e-287 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LHCGIODF_01899 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
LHCGIODF_01900 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
LHCGIODF_01901 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
LHCGIODF_01902 0.0 ytdP - - K - - - Transcriptional regulator
LHCGIODF_01903 1.31e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
LHCGIODF_01904 1.18e-278 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
LHCGIODF_01905 6.78e-94 yteS - - G - - - transport
LHCGIODF_01906 1.2e-314 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
LHCGIODF_01907 3.13e-149 yteU - - S - - - Integral membrane protein
LHCGIODF_01908 2.14e-36 yteV - - S - - - Sporulation protein Cse60
LHCGIODF_01909 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
LHCGIODF_01910 5.74e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
LHCGIODF_01911 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LHCGIODF_01912 1.75e-168 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LHCGIODF_01913 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
LHCGIODF_01914 2.8e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LHCGIODF_01915 4.99e-255 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
LHCGIODF_01916 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
LHCGIODF_01917 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
LHCGIODF_01918 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LHCGIODF_01919 2.04e-128 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LHCGIODF_01920 8.15e-211 ytlQ - - - - - - -
LHCGIODF_01921 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LHCGIODF_01922 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LHCGIODF_01923 3.02e-192 ytmP - - M - - - Phosphotransferase
LHCGIODF_01924 9.51e-61 ytzH - - S - - - YtzH-like protein
LHCGIODF_01925 8.79e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LHCGIODF_01926 1.3e-191 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LHCGIODF_01927 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LHCGIODF_01928 3.34e-67 ytzB - - S - - - small secreted protein
LHCGIODF_01929 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
LHCGIODF_01930 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
LHCGIODF_01931 3.17e-75 ytpP - - CO - - - Thioredoxin
LHCGIODF_01932 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
LHCGIODF_01933 1.03e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LHCGIODF_01934 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LHCGIODF_01935 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LHCGIODF_01936 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LHCGIODF_01937 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
LHCGIODF_01938 2.23e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
LHCGIODF_01939 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LHCGIODF_01940 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LHCGIODF_01941 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LHCGIODF_01942 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LHCGIODF_01943 1.81e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
LHCGIODF_01944 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
LHCGIODF_01945 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LHCGIODF_01946 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LHCGIODF_01947 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LHCGIODF_01949 3.83e-202 - - - L - - - Belongs to the 'phage' integrase family
LHCGIODF_01950 9.97e-59 - - - E - - - IrrE N-terminal-like domain
LHCGIODF_01951 1.05e-18 yvaO - - K ko:K22299 - ko00000,ko03000 sequence-specific DNA binding
LHCGIODF_01953 7.96e-41 - - - - - - - -
LHCGIODF_01956 3.31e-26 - - - - - - - -
LHCGIODF_01957 1.42e-101 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
LHCGIODF_01960 2.7e-128 - - - L - - - DnaD domain protein
LHCGIODF_01961 9.77e-18 - - - S - - - Loader and inhibitor of phage G40P
LHCGIODF_01962 3.8e-211 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 replicative DNA helicase
LHCGIODF_01963 7.58e-31 - - - - - - - -
LHCGIODF_01964 3.01e-12 - - - S - - - Phage-like element PBSX protein XtrA
LHCGIODF_01965 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
LHCGIODF_01966 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LHCGIODF_01967 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LHCGIODF_01968 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LHCGIODF_01969 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LHCGIODF_01970 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
LHCGIODF_01971 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
LHCGIODF_01972 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LHCGIODF_01973 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LHCGIODF_01975 1.93e-53 - - - - - - - -
LHCGIODF_01976 7.05e-293 - - - S - - - Bacterial EndoU nuclease
LHCGIODF_01979 4.31e-82 yozB - - S ko:K08976 - ko00000 Membrane
LHCGIODF_01980 1.19e-30 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
LHCGIODF_01981 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
LHCGIODF_01982 1.51e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
LHCGIODF_01983 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
LHCGIODF_01984 1.73e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
LHCGIODF_01985 3.1e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
LHCGIODF_01986 4.25e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LHCGIODF_01987 8.23e-170 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
LHCGIODF_01988 4.21e-202 ydjI - - S - - - virion core protein (lumpy skin disease virus)
LHCGIODF_01989 5.58e-248 - - - S - - - Ion transport 2 domain protein
LHCGIODF_01990 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHCGIODF_01991 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
LHCGIODF_01992 1.79e-84 ydjM - - M - - - Lytic transglycolase
LHCGIODF_01993 2.81e-208 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
LHCGIODF_01995 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
LHCGIODF_01996 3.21e-205 - - - I - - - Alpha/beta hydrolase family
LHCGIODF_01997 7.12e-229 yeaA - - S - - - Protein of unknown function (DUF4003)
LHCGIODF_01998 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
LHCGIODF_01999 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LHCGIODF_02000 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LHCGIODF_02001 3.25e-225 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
LHCGIODF_02002 5.31e-284 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LHCGIODF_02003 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
LHCGIODF_02004 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LHCGIODF_02005 3.8e-112 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHCGIODF_02006 3.66e-311 - - - S - - - Domain of unknown function (DUF4179)
LHCGIODF_02007 4.86e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LHCGIODF_02008 5.85e-165 yebC - - M - - - Membrane
LHCGIODF_02010 2.66e-120 yebE - - S - - - UPF0316 protein
LHCGIODF_02011 3.13e-38 yebG - - S - - - NETI protein
LHCGIODF_02012 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LHCGIODF_02013 7.39e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LHCGIODF_02014 8.03e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LHCGIODF_02015 1.18e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LHCGIODF_02016 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHCGIODF_02017 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHCGIODF_02018 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHCGIODF_02019 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LHCGIODF_02020 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LHCGIODF_02021 7.3e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LHCGIODF_02022 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LHCGIODF_02023 1.63e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LHCGIODF_02024 1.06e-95 - - - K - - - helix_turn_helix ASNC type
LHCGIODF_02025 1.67e-291 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
LHCGIODF_02026 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
LHCGIODF_02027 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
LHCGIODF_02028 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
LHCGIODF_02029 7.62e-68 yerC - - S - - - protein conserved in bacteria
LHCGIODF_02030 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
LHCGIODF_02032 9.04e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LHCGIODF_02033 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LHCGIODF_02034 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LHCGIODF_02035 3.57e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
LHCGIODF_02036 2.99e-251 yerI - - S - - - homoserine kinase type II (protein kinase fold)
LHCGIODF_02037 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
LHCGIODF_02038 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LHCGIODF_02039 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHCGIODF_02041 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHCGIODF_02042 4.91e-189 yerO - - K - - - Transcriptional regulator
LHCGIODF_02043 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LHCGIODF_02044 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LHCGIODF_02045 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LHCGIODF_02046 8.51e-06 - - - - - - - -
LHCGIODF_02047 2.52e-102 - - - S - - - Protein of unknown function, DUF600
LHCGIODF_02048 2.39e-68 - - - S - - - Protein of unknown function, DUF600
LHCGIODF_02049 2.48e-66 - - - S - - - Protein of unknown function, DUF600
LHCGIODF_02050 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
LHCGIODF_02052 8.06e-126 - - - L - - - endonuclease activity
LHCGIODF_02053 4.98e-15 - - - S - - - Lysozyme inhibitor LprI
LHCGIODF_02054 2.57e-273 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
LHCGIODF_02056 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
LHCGIODF_02058 2.44e-130 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_02059 4.95e-107 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
LHCGIODF_02060 5.83e-194 yesF - - GM - - - NAD(P)H-binding
LHCGIODF_02061 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
LHCGIODF_02062 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
LHCGIODF_02063 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
LHCGIODF_02064 9.78e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
LHCGIODF_02066 1.95e-132 yesL - - S - - - Protein of unknown function, DUF624
LHCGIODF_02067 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_02068 2.93e-259 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
LHCGIODF_02069 4.13e-314 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LHCGIODF_02070 4.76e-217 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHCGIODF_02071 5.33e-212 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHCGIODF_02072 3.26e-253 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
LHCGIODF_02073 0.0 yesS - - K - - - Transcriptional regulator
LHCGIODF_02074 1.19e-169 - - - E - - - GDSL-like Lipase/Acylhydrolase
LHCGIODF_02075 1.25e-163 yesU - - S - - - Domain of unknown function (DUF1961)
LHCGIODF_02076 4.02e-145 - - - S - - - Protein of unknown function, DUF624
LHCGIODF_02077 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
LHCGIODF_02078 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
LHCGIODF_02080 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
LHCGIODF_02081 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
LHCGIODF_02082 0.0 yetA - - - - - - -
LHCGIODF_02083 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LHCGIODF_02084 2.78e-225 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
LHCGIODF_02085 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHCGIODF_02086 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
LHCGIODF_02087 1.81e-157 yetF - - S - - - membrane
LHCGIODF_02088 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
LHCGIODF_02089 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHCGIODF_02090 1.75e-44 - - - - - - - -
LHCGIODF_02091 7.23e-184 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LHCGIODF_02092 4.46e-27 yezD - - S - - - Uncharacterized small protein (DUF2292)
LHCGIODF_02093 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
LHCGIODF_02094 1.42e-200 - - - EG - - - EamA-like transporter family
LHCGIODF_02095 1.86e-114 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHCGIODF_02096 2.43e-263 yetM - - CH - - - FAD binding domain
LHCGIODF_02097 2.55e-65 - - - - - - - -
LHCGIODF_02098 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHCGIODF_02099 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHCGIODF_02100 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHCGIODF_02101 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHCGIODF_02102 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
LHCGIODF_02103 2.48e-83 yngL - - S - - - Protein of unknown function (DUF1360)
LHCGIODF_02104 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
LHCGIODF_02105 5.35e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LHCGIODF_02106 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LHCGIODF_02107 6.65e-315 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
LHCGIODF_02108 8.37e-42 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
LHCGIODF_02109 9.56e-212 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
LHCGIODF_02110 6.03e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
LHCGIODF_02111 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LHCGIODF_02112 7.39e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
LHCGIODF_02113 2.01e-134 yngC - - S - - - membrane-associated protein
LHCGIODF_02114 5.53e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LHCGIODF_02115 9.97e-103 yngA - - S - - - membrane
LHCGIODF_02116 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LHCGIODF_02117 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
LHCGIODF_02119 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
LHCGIODF_02120 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LHCGIODF_02121 8.74e-75 ynfC - - - - - - -
LHCGIODF_02122 7.45e-18 - - - - - - - -
LHCGIODF_02123 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LHCGIODF_02124 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LHCGIODF_02125 1.72e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
LHCGIODF_02126 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LHCGIODF_02127 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
LHCGIODF_02128 5.48e-70 yneQ - - - - - - -
LHCGIODF_02129 2.72e-93 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
LHCGIODF_02130 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
LHCGIODF_02132 9.26e-10 - - - S - - - Fur-regulated basic protein B
LHCGIODF_02133 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LHCGIODF_02134 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LHCGIODF_02135 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
LHCGIODF_02136 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
LHCGIODF_02137 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
LHCGIODF_02138 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
LHCGIODF_02139 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
LHCGIODF_02140 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
LHCGIODF_02141 1.68e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
LHCGIODF_02142 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
LHCGIODF_02143 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
LHCGIODF_02144 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
LHCGIODF_02145 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LHCGIODF_02146 1.15e-43 ynzC - - S - - - UPF0291 protein
LHCGIODF_02147 2.29e-144 yneB - - L - - - resolvase
LHCGIODF_02148 2.44e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LHCGIODF_02149 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LHCGIODF_02150 2.47e-101 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LHCGIODF_02151 3.79e-96 yndM - - S - - - Protein of unknown function (DUF2512)
LHCGIODF_02152 2.57e-172 yndL - - S - - - Replication protein
LHCGIODF_02154 0.0 yndJ - - S - - - YndJ-like protein
LHCGIODF_02155 1.21e-149 - - - S - - - Domain of unknown function (DUF4166)
LHCGIODF_02156 1.2e-194 yndG - - S - - - DoxX-like family
LHCGIODF_02157 5.12e-285 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
LHCGIODF_02158 9.26e-249 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
LHCGIODF_02159 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LHCGIODF_02162 1.81e-103 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
LHCGIODF_02163 1.04e-94 - - - - - - - -
LHCGIODF_02164 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
LHCGIODF_02167 2.17e-165 - - - S - - - Domain of unknown function, YrpD
LHCGIODF_02169 3.91e-210 - - - S - - - Thymidylate synthase
LHCGIODF_02171 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
LHCGIODF_02172 9.48e-108 - - - S - - - Protein of unknown function (DUF2691)
LHCGIODF_02174 5.91e-279 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LHCGIODF_02175 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHCGIODF_02176 7.18e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
LHCGIODF_02177 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
LHCGIODF_02178 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
LHCGIODF_02179 5.23e-277 xylR - - GK - - - ROK family
LHCGIODF_02180 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LHCGIODF_02181 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
LHCGIODF_02182 1.56e-103 - - - E - - - phosphoribosylanthranilate isomerase activity
LHCGIODF_02183 9.53e-160 - - - S - - - Domain of unknown function (DUF3885)
LHCGIODF_02184 5.75e-124 ynaD - - J - - - Acetyltransferase (GNAT) domain
LHCGIODF_02185 6.63e-122 - - - G - - - SMI1-KNR4 cell-wall
LHCGIODF_02186 4.15e-49 - - - - - - - -
LHCGIODF_02187 2.44e-155 - - - - - - - -
LHCGIODF_02189 2.16e-14 - - - - - - - -
LHCGIODF_02191 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LHCGIODF_02192 4.05e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
LHCGIODF_02193 4.78e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LHCGIODF_02194 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LHCGIODF_02195 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
LHCGIODF_02196 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
LHCGIODF_02197 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
LHCGIODF_02198 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LHCGIODF_02199 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
LHCGIODF_02200 1e-306 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LHCGIODF_02201 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
LHCGIODF_02202 1.51e-78 ylxF - - S - - - MgtE intracellular N domain
LHCGIODF_02203 2.61e-304 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
LHCGIODF_02204 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
LHCGIODF_02205 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
LHCGIODF_02206 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
LHCGIODF_02207 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LHCGIODF_02208 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LHCGIODF_02209 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
LHCGIODF_02210 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
LHCGIODF_02211 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
LHCGIODF_02212 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
LHCGIODF_02213 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
LHCGIODF_02214 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LHCGIODF_02215 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LHCGIODF_02216 5.42e-254 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
LHCGIODF_02217 4.46e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
LHCGIODF_02218 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LHCGIODF_02219 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
LHCGIODF_02220 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
LHCGIODF_02221 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LHCGIODF_02222 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LHCGIODF_02223 1.33e-175 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHCGIODF_02224 1.15e-99 ylxL - - - - - - -
LHCGIODF_02225 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LHCGIODF_02226 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LHCGIODF_02227 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LHCGIODF_02228 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LHCGIODF_02229 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LHCGIODF_02230 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LHCGIODF_02231 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LHCGIODF_02232 4.72e-285 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LHCGIODF_02233 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LHCGIODF_02234 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LHCGIODF_02235 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LHCGIODF_02236 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LHCGIODF_02237 1.66e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
LHCGIODF_02238 6.16e-63 ylxQ - - J - - - ribosomal protein
LHCGIODF_02239 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LHCGIODF_02240 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
LHCGIODF_02241 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LHCGIODF_02242 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LHCGIODF_02243 2.22e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LHCGIODF_02244 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LHCGIODF_02245 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LHCGIODF_02246 2.4e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
LHCGIODF_02247 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
LHCGIODF_02248 1.53e-56 ymxH - - S - - - YlmC YmxH family
LHCGIODF_02249 1.52e-207 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
LHCGIODF_02250 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LHCGIODF_02251 5.56e-246 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LHCGIODF_02252 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LHCGIODF_02253 6.39e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LHCGIODF_02254 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LHCGIODF_02255 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
LHCGIODF_02256 4.94e-44 - - - S - - - YlzJ-like protein
LHCGIODF_02257 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LHCGIODF_02258 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_02259 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LHCGIODF_02260 3.31e-299 albE - - S - - - Peptidase M16
LHCGIODF_02261 5.35e-306 ymfH - - S - - - zinc protease
LHCGIODF_02262 1.49e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LHCGIODF_02263 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
LHCGIODF_02264 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
LHCGIODF_02265 8.75e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
LHCGIODF_02266 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LHCGIODF_02267 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
LHCGIODF_02268 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LHCGIODF_02269 1.82e-276 pbpX - - V - - - Beta-lactamase
LHCGIODF_02270 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LHCGIODF_02271 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
LHCGIODF_02272 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
LHCGIODF_02273 8.31e-253 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LHCGIODF_02274 1.89e-274 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LHCGIODF_02275 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LHCGIODF_02276 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
LHCGIODF_02277 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
LHCGIODF_02278 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LHCGIODF_02279 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LHCGIODF_02280 1.91e-91 - - - S - - - Regulatory protein YrvL
LHCGIODF_02282 2.67e-125 ymcC - - S - - - Membrane
LHCGIODF_02283 1.24e-135 pksA - - K - - - Transcriptional regulator
LHCGIODF_02284 8.03e-81 ymzB - - - - - - -
LHCGIODF_02285 2.67e-207 - - - S - - - Metallo-beta-lactamase superfamily
LHCGIODF_02286 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
LHCGIODF_02288 3.96e-163 ymaC - - S - - - Replication protein
LHCGIODF_02289 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
LHCGIODF_02290 2.23e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
LHCGIODF_02291 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LHCGIODF_02293 5.41e-76 ymaF - - S - - - YmaF family
LHCGIODF_02294 1.38e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LHCGIODF_02295 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LHCGIODF_02296 1.63e-31 - - - - - - - -
LHCGIODF_02297 1.2e-30 ymzA - - - - - - -
LHCGIODF_02298 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
LHCGIODF_02299 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LHCGIODF_02300 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LHCGIODF_02301 1.76e-138 - - - - - - - -
LHCGIODF_02302 2.72e-148 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LHCGIODF_02303 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
LHCGIODF_02304 5.95e-263 yraM - - S - - - PrpF protein
LHCGIODF_02305 3.87e-200 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LHCGIODF_02306 1.45e-55 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHCGIODF_02307 6.66e-192 - - - S - - - Alpha beta hydrolase
LHCGIODF_02308 7.73e-79 - - - T - - - sh3 domain protein
LHCGIODF_02309 1.44e-79 - - - T - - - sh3 domain protein
LHCGIODF_02310 3.15e-85 - - - E - - - Glyoxalase-like domain
LHCGIODF_02311 4.19e-50 yraG - - - ko:K06440 - ko00000 -
LHCGIODF_02312 9.61e-84 yraF - - M - - - Spore coat protein
LHCGIODF_02313 4.84e-279 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LHCGIODF_02314 1.23e-35 yraE - - - ko:K06440 - ko00000 -
LHCGIODF_02315 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
LHCGIODF_02316 1.83e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
LHCGIODF_02317 2.9e-10 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
LHCGIODF_02318 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
LHCGIODF_02319 2.25e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LHCGIODF_02320 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
LHCGIODF_02321 3.27e-191 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
LHCGIODF_02322 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
LHCGIODF_02323 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
LHCGIODF_02324 5.36e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LHCGIODF_02325 0.0 levR - - K - - - PTS system fructose IIA component
LHCGIODF_02326 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LHCGIODF_02327 4.63e-136 yrhP - - E - - - LysE type translocator
LHCGIODF_02328 5.9e-194 yrhO - - K - - - Archaeal transcriptional regulator TrmB
LHCGIODF_02329 2.37e-185 rsiV - - S - - - Protein of unknown function (DUF3298)
LHCGIODF_02330 0.0 oatA - - I - - - Acyltransferase family
LHCGIODF_02331 6.32e-59 yrhK - - S - - - YrhK-like protein
LHCGIODF_02332 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LHCGIODF_02333 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
LHCGIODF_02334 8.67e-124 yrhH - - Q - - - methyltransferase
LHCGIODF_02335 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
LHCGIODF_02337 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
LHCGIODF_02338 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
LHCGIODF_02339 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
LHCGIODF_02340 6.05e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
LHCGIODF_02341 6.93e-49 yrhC - - S - - - YrhC-like protein
LHCGIODF_02342 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LHCGIODF_02343 1.66e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
LHCGIODF_02344 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LHCGIODF_02345 3.44e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
LHCGIODF_02346 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
LHCGIODF_02347 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
LHCGIODF_02348 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
LHCGIODF_02349 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LHCGIODF_02350 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LHCGIODF_02351 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
LHCGIODF_02352 6.3e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
LHCGIODF_02353 1.98e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
LHCGIODF_02354 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LHCGIODF_02355 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
LHCGIODF_02356 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LHCGIODF_02357 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
LHCGIODF_02358 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LHCGIODF_02359 1.25e-241 yrrI - - S - - - AI-2E family transporter
LHCGIODF_02360 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LHCGIODF_02361 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LHCGIODF_02362 2.28e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHCGIODF_02363 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHCGIODF_02364 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
LHCGIODF_02365 8.4e-42 yrzR - - - - - - -
LHCGIODF_02366 1.44e-107 yrrD - - S - - - protein conserved in bacteria
LHCGIODF_02367 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LHCGIODF_02368 1.02e-38 yrrB - - S - - - COG0457 FOG TPR repeat
LHCGIODF_02369 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LHCGIODF_02370 2.98e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LHCGIODF_02371 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_02372 6.69e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LHCGIODF_02373 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LHCGIODF_02374 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LHCGIODF_02375 7.06e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LHCGIODF_02377 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
LHCGIODF_02378 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LHCGIODF_02379 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LHCGIODF_02380 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LHCGIODF_02381 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LHCGIODF_02382 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
LHCGIODF_02383 2.65e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LHCGIODF_02384 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LHCGIODF_02385 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
LHCGIODF_02386 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LHCGIODF_02387 5.83e-143 yrbG - - S - - - membrane
LHCGIODF_02388 1.46e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
LHCGIODF_02389 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
LHCGIODF_02390 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LHCGIODF_02391 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LHCGIODF_02392 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
LHCGIODF_02393 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LHCGIODF_02394 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LHCGIODF_02395 1.85e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
LHCGIODF_02396 0.0 csbX - - EGP - - - the major facilitator superfamily
LHCGIODF_02397 4.59e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
LHCGIODF_02398 1.91e-151 yrzF - - T - - - serine threonine protein kinase
LHCGIODF_02400 6.26e-68 - - - S - - - Family of unknown function (DUF5412)
LHCGIODF_02401 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
LHCGIODF_02402 8.63e-165 yebC - - K - - - transcriptional regulatory protein
LHCGIODF_02403 2.55e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LHCGIODF_02404 2.43e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
LHCGIODF_02405 1.32e-271 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LHCGIODF_02406 8.4e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
LHCGIODF_02407 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
LHCGIODF_02408 2.36e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LHCGIODF_02409 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
LHCGIODF_02410 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
LHCGIODF_02411 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
LHCGIODF_02412 9.2e-197 - - - - - - - -
LHCGIODF_02413 3.34e-24 - - - - - - - -
LHCGIODF_02414 1.44e-24 - - - - - - - -
LHCGIODF_02415 1.11e-151 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LHCGIODF_02416 2.41e-142 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHCGIODF_02417 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
LHCGIODF_02418 2.9e-64 - - - L - - - Recombinase zinc beta ribbon domain
LHCGIODF_02419 3.23e-220 - - - V ko:K07448 - ko00000,ko02048 Restriction endonuclease
LHCGIODF_02420 2.23e-11 spoIVCA - - L ko:K06400 - ko00000 Recombinase
LHCGIODF_02421 1.17e-90 spoIVCA - - L ko:K06400 - ko00000 Recombinase
LHCGIODF_02422 8.44e-21 spoIVCA - - L ko:K06400 - ko00000 Recombinase
LHCGIODF_02423 7.1e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LHCGIODF_02425 6.92e-82 - - - - - - - -
LHCGIODF_02426 4.43e-89 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LHCGIODF_02427 1.96e-169 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LHCGIODF_02429 8.79e-38 yycQ - - S - - - Protein of unknown function (DUF2651)
LHCGIODF_02430 2.39e-258 yycP - - - - - - -
LHCGIODF_02431 2.78e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LHCGIODF_02432 2.6e-111 yycN - - K - - - Acetyltransferase
LHCGIODF_02433 2.38e-236 - - - S - - - aspartate phosphatase
LHCGIODF_02435 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LHCGIODF_02436 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LHCGIODF_02437 2.89e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
LHCGIODF_02438 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LHCGIODF_02439 9.43e-279 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LHCGIODF_02440 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LHCGIODF_02441 1.2e-200 yycI - - S - - - protein conserved in bacteria
LHCGIODF_02442 0.0 yycH - - S - - - protein conserved in bacteria
LHCGIODF_02443 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_02444 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHCGIODF_02449 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LHCGIODF_02450 1.34e-98 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHCGIODF_02451 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LHCGIODF_02452 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
LHCGIODF_02454 1.89e-22 yycC - - K - - - YycC-like protein
LHCGIODF_02455 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
LHCGIODF_02456 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LHCGIODF_02457 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LHCGIODF_02458 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LHCGIODF_02459 7.43e-205 yybS - - S - - - membrane
LHCGIODF_02461 5.61e-108 cotF - - M ko:K06329 - ko00000 Spore coat protein
LHCGIODF_02462 6.68e-90 yybR - - K - - - Transcriptional regulator
LHCGIODF_02463 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
LHCGIODF_02464 2.34e-92 - - - - - - - -
LHCGIODF_02466 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LHCGIODF_02467 4.38e-142 - - - K - - - TipAS antibiotic-recognition domain
LHCGIODF_02468 6.12e-185 - - - - - - - -
LHCGIODF_02469 3.02e-88 - - - S - - - SnoaL-like domain
LHCGIODF_02470 1.89e-160 yybG - - S - - - Pentapeptide repeat-containing protein
LHCGIODF_02471 4.31e-277 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LHCGIODF_02472 2.53e-208 yybE - - K - - - Transcriptional regulator
LHCGIODF_02473 2.55e-100 yjcF - - S - - - Acetyltransferase (GNAT) domain
LHCGIODF_02474 1.22e-97 yybC - - - - - - -
LHCGIODF_02475 2.16e-164 - - - S - - - Metallo-beta-lactamase superfamily
LHCGIODF_02476 4.54e-100 yybA - - K - - - transcriptional
LHCGIODF_02477 1.16e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
LHCGIODF_02478 4.28e-125 yyaS - - S ko:K07149 - ko00000 Membrane
LHCGIODF_02479 2.07e-123 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
LHCGIODF_02480 1.09e-87 - - - S - - - YjbR
LHCGIODF_02481 2.2e-139 yyaP - - H - - - RibD C-terminal domain
LHCGIODF_02482 1.29e-18 yddB - - S - - - Conjugative transposon protein TcpC
LHCGIODF_02485 1.3e-58 yddA - - - - - - -
LHCGIODF_02490 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
LHCGIODF_02491 8.91e-217 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
LHCGIODF_02492 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
LHCGIODF_02493 1.14e-130 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
LHCGIODF_02494 7.2e-90 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHCGIODF_02495 3.03e-230 ccpB - - K - - - Transcriptional regulator
LHCGIODF_02496 2.07e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LHCGIODF_02497 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LHCGIODF_02498 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LHCGIODF_02499 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LHCGIODF_02500 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LHCGIODF_02501 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LHCGIODF_02502 7.41e-45 yyzM - - S - - - protein conserved in bacteria
LHCGIODF_02503 5.34e-227 yyaD - - S - - - Membrane
LHCGIODF_02504 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
LHCGIODF_02505 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LHCGIODF_02506 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
LHCGIODF_02507 2.27e-98 - - - S - - - Bacterial PH domain
LHCGIODF_02508 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LHCGIODF_02509 1.68e-166 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LHCGIODF_02510 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LHCGIODF_02511 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LHCGIODF_02512 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
LHCGIODF_02513 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LHCGIODF_02514 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LHCGIODF_02515 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LHCGIODF_02516 3.03e-257 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LHCGIODF_02517 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
LHCGIODF_02518 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LHCGIODF_02519 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
LHCGIODF_02520 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LHCGIODF_02521 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LHCGIODF_02522 3.05e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LHCGIODF_02523 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
LHCGIODF_02524 8.33e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
LHCGIODF_02525 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LHCGIODF_02526 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LHCGIODF_02527 3.53e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
LHCGIODF_02528 1.14e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LHCGIODF_02529 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
LHCGIODF_02530 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
LHCGIODF_02531 5.06e-86 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHCGIODF_02532 3.35e-56 - - - - - - - -
LHCGIODF_02534 4.87e-260 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
LHCGIODF_02535 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
LHCGIODF_02536 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LHCGIODF_02537 9.59e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
LHCGIODF_02538 1.44e-198 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHCGIODF_02539 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
LHCGIODF_02540 7.86e-208 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
LHCGIODF_02541 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
LHCGIODF_02542 2.95e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHCGIODF_02543 4.42e-216 bsn - - L - - - Ribonuclease
LHCGIODF_02544 3.96e-293 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LHCGIODF_02545 5.74e-304 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LHCGIODF_02546 4.85e-232 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LHCGIODF_02547 7.22e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
LHCGIODF_02548 4.27e-188 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LHCGIODF_02549 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LHCGIODF_02550 2.95e-123 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LHCGIODF_02551 1.47e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
LHCGIODF_02552 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
LHCGIODF_02553 1.84e-282 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
LHCGIODF_02554 6.93e-299 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
LHCGIODF_02555 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
LHCGIODF_02556 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LHCGIODF_02557 5.95e-77 yunG - - - - - - -
LHCGIODF_02558 7.07e-219 yunF - - S - - - Protein of unknown function DUF72
LHCGIODF_02559 1.86e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
LHCGIODF_02560 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LHCGIODF_02561 8.06e-64 yunC - - S - - - Domain of unknown function (DUF1805)
LHCGIODF_02562 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
LHCGIODF_02563 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
LHCGIODF_02564 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LHCGIODF_02565 2.71e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LHCGIODF_02566 3.2e-63 yutD - - S - - - protein conserved in bacteria
LHCGIODF_02567 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
LHCGIODF_02568 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LHCGIODF_02569 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
LHCGIODF_02570 4.63e-255 yutH - - S - - - Spore coat protein
LHCGIODF_02571 6.79e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LHCGIODF_02572 1.14e-251 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LHCGIODF_02573 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LHCGIODF_02574 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
LHCGIODF_02575 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
LHCGIODF_02576 2.7e-74 yuzD - - S - - - protein conserved in bacteria
LHCGIODF_02577 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LHCGIODF_02578 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
LHCGIODF_02579 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LHCGIODF_02580 2.25e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LHCGIODF_02581 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
LHCGIODF_02582 1.39e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHCGIODF_02583 2.84e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
LHCGIODF_02584 3.7e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LHCGIODF_02586 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
LHCGIODF_02587 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LHCGIODF_02588 9.78e-47 yuiB - - S - - - Putative membrane protein
LHCGIODF_02589 1.5e-149 yuiC - - S - - - protein conserved in bacteria
LHCGIODF_02590 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
LHCGIODF_02591 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LHCGIODF_02592 4.25e-278 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
LHCGIODF_02593 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
LHCGIODF_02594 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
LHCGIODF_02595 1.04e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
LHCGIODF_02596 2.89e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHCGIODF_02597 2.45e-289 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LHCGIODF_02598 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
LHCGIODF_02599 6.09e-226 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
LHCGIODF_02600 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHCGIODF_02601 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
LHCGIODF_02602 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
LHCGIODF_02603 1.64e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
LHCGIODF_02604 5.72e-290 yukF - - QT - - - Transcriptional regulator
LHCGIODF_02605 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
LHCGIODF_02606 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
LHCGIODF_02607 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
LHCGIODF_02608 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LHCGIODF_02610 2.7e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LHCGIODF_02611 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
LHCGIODF_02612 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_02613 9.29e-250 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
LHCGIODF_02614 3.84e-171 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHCGIODF_02615 7.95e-45 - - - - - - - -
LHCGIODF_02616 8.02e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
LHCGIODF_02617 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
LHCGIODF_02618 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LHCGIODF_02619 3.19e-225 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LHCGIODF_02620 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LHCGIODF_02621 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LHCGIODF_02622 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LHCGIODF_02623 3.05e-190 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
LHCGIODF_02624 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
LHCGIODF_02625 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LHCGIODF_02627 0.0 - - - - - - - -
LHCGIODF_02628 2.8e-27 - - - - - - - -
LHCGIODF_02629 1.06e-110 - - - - - - - -
LHCGIODF_02630 2e-72 - - - - - - - -
LHCGIODF_02631 1.34e-75 - - - - - - - -
LHCGIODF_02632 7.95e-116 - - - S - - - Predicted membrane protein (DUF2339)
LHCGIODF_02633 3.68e-141 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
LHCGIODF_02634 2.29e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LHCGIODF_02635 7.64e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LHCGIODF_02636 8.08e-147 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LHCGIODF_02637 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
LHCGIODF_02638 1.05e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LHCGIODF_02639 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LHCGIODF_02640 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LHCGIODF_02641 2.14e-179 yvpB - - NU - - - protein conserved in bacteria
LHCGIODF_02642 1.05e-151 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
LHCGIODF_02643 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LHCGIODF_02644 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LHCGIODF_02645 2.06e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
LHCGIODF_02646 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LHCGIODF_02647 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LHCGIODF_02648 2.81e-278 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LHCGIODF_02649 1.95e-162 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LHCGIODF_02650 3.02e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
LHCGIODF_02651 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
LHCGIODF_02652 4.13e-104 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHCGIODF_02653 9.32e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LHCGIODF_02654 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
LHCGIODF_02655 1.03e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHCGIODF_02656 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
LHCGIODF_02657 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
LHCGIODF_02658 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LHCGIODF_02659 5.54e-219 yvlB - - S - - - Putative adhesin
LHCGIODF_02660 8.09e-65 yvlA - - - - - - -
LHCGIODF_02661 2.25e-45 yvkN - - - - - - -
LHCGIODF_02662 1.68e-157 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LHCGIODF_02663 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LHCGIODF_02664 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LHCGIODF_02665 2.54e-42 csbA - - S - - - protein conserved in bacteria
LHCGIODF_02666 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
LHCGIODF_02667 4.09e-131 yvkB - - K - - - Transcriptional regulator
LHCGIODF_02668 1.23e-294 yvkA - - P - - - -transporter
LHCGIODF_02669 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LHCGIODF_02670 1.38e-73 swrA - - S - - - Swarming motility protein
LHCGIODF_02671 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LHCGIODF_02672 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LHCGIODF_02673 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
LHCGIODF_02674 3.78e-74 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LHCGIODF_02675 1.86e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LHCGIODF_02676 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LHCGIODF_02677 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LHCGIODF_02678 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LHCGIODF_02679 9.14e-88 - - - - - - - -
LHCGIODF_02680 1.73e-08 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
LHCGIODF_02681 2.1e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
LHCGIODF_02682 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LHCGIODF_02683 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
LHCGIODF_02684 3.11e-143 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LHCGIODF_02685 1.23e-39 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LHCGIODF_02686 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LHCGIODF_02687 1.7e-92 yviE - - - - - - -
LHCGIODF_02688 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
LHCGIODF_02689 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
LHCGIODF_02690 9.24e-98 yvyG - - NOU - - - FlgN protein
LHCGIODF_02691 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
LHCGIODF_02692 1.83e-96 yvyF - - S - - - flagellar protein
LHCGIODF_02693 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
LHCGIODF_02694 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
LHCGIODF_02695 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LHCGIODF_02696 2.51e-198 degV - - S - - - protein conserved in bacteria
LHCGIODF_02697 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHCGIODF_02698 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LHCGIODF_02699 1.94e-136 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
LHCGIODF_02700 1.23e-151 - - - K - - - Transcriptional regulator
LHCGIODF_02704 6.81e-25 - - - S - - - protein conserved in bacteria
LHCGIODF_02707 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
LHCGIODF_02708 2.26e-269 yfjB - - - - - - -
LHCGIODF_02709 2.5e-185 yfjC - - - - - - -
LHCGIODF_02710 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
LHCGIODF_02711 1.07e-100 - - - S - - - Family of unknown function (DUF5381)
LHCGIODF_02712 1.05e-74 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
LHCGIODF_02713 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
LHCGIODF_02714 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
LHCGIODF_02715 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LHCGIODF_02716 2.22e-260 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LHCGIODF_02717 6.47e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LHCGIODF_02718 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LHCGIODF_02720 2.53e-106 yfjM - - S - - - Psort location Cytoplasmic, score
LHCGIODF_02721 9.53e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LHCGIODF_02722 3.04e-59 - - - S - - - YfzA-like protein
LHCGIODF_02723 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LHCGIODF_02724 7.91e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LHCGIODF_02725 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
LHCGIODF_02726 4.43e-190 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LHCGIODF_02727 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
LHCGIODF_02728 3.26e-36 yfjT - - - - - - -
LHCGIODF_02729 1.19e-281 yfkA - - S - - - YfkB-like domain
LHCGIODF_02730 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
LHCGIODF_02731 3.69e-189 yfkD - - S - - - YfkD-like protein
LHCGIODF_02732 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
LHCGIODF_02733 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LHCGIODF_02734 1.64e-12 - - - - - - - -
LHCGIODF_02735 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LHCGIODF_02736 1.03e-66 yfkI - - S - - - gas vesicle protein
LHCGIODF_02737 9.78e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LHCGIODF_02738 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
LHCGIODF_02739 5.1e-265 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LHCGIODF_02740 2.23e-113 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LHCGIODF_02741 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LHCGIODF_02742 6.16e-160 frp - - C - - - nitroreductase
LHCGIODF_02743 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
LHCGIODF_02744 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
LHCGIODF_02745 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHCGIODF_02746 1.36e-32 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
LHCGIODF_02747 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
LHCGIODF_02748 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
LHCGIODF_02749 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LHCGIODF_02750 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LHCGIODF_02751 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LHCGIODF_02752 1.48e-65 yflH - - S - - - Protein of unknown function (DUF3243)
LHCGIODF_02753 6.9e-27 yflI - - - - - - -
LHCGIODF_02754 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
LHCGIODF_02755 3.42e-157 yflK - - S - - - protein conserved in bacteria
LHCGIODF_02756 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LHCGIODF_02757 5.59e-275 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LHCGIODF_02758 1.7e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LHCGIODF_02759 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LHCGIODF_02760 1.62e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
LHCGIODF_02761 2.2e-151 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LHCGIODF_02762 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LHCGIODF_02763 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LHCGIODF_02764 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
LHCGIODF_02765 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
LHCGIODF_02766 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
LHCGIODF_02767 1.17e-220 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LHCGIODF_02768 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHCGIODF_02769 2.01e-221 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHCGIODF_02770 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LHCGIODF_02771 9.5e-239 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
LHCGIODF_02772 1.53e-97 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
LHCGIODF_02773 4.19e-263 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
LHCGIODF_02774 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LHCGIODF_02775 5.23e-35 - - - - - - - -
LHCGIODF_02776 7.24e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
LHCGIODF_02777 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
LHCGIODF_02778 7.28e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
LHCGIODF_02779 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LHCGIODF_02780 7.3e-161 yfmS - - NT - - - chemotaxis protein
LHCGIODF_02781 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LHCGIODF_02782 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
LHCGIODF_02783 2.49e-166 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LHCGIODF_02784 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LHCGIODF_02785 3.88e-242 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
LHCGIODF_02786 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
LHCGIODF_02787 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
LHCGIODF_02788 2.95e-238 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
LHCGIODF_02789 9.83e-187 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
LHCGIODF_02790 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LHCGIODF_02791 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LHCGIODF_02792 7.06e-251 yetN - - S - - - Protein of unknown function (DUF3900)
LHCGIODF_02793 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LHCGIODF_02794 5.07e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LHCGIODF_02795 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LHCGIODF_02796 0.0 ywqB - - S - - - SWIM zinc finger
LHCGIODF_02797 3.6e-25 - - - - - - - -
LHCGIODF_02798 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
LHCGIODF_02799 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LHCGIODF_02800 5.87e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
LHCGIODF_02801 4.66e-313 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LHCGIODF_02802 4.19e-196 ywqG - - S - - - Domain of unknown function (DUF1963)
LHCGIODF_02804 2.17e-52 ywqI - - S - - - Family of unknown function (DUF5344)
LHCGIODF_02805 2.05e-312 ywqJ - - S - - - Pre-toxin TG
LHCGIODF_02806 1.01e-61 - - - - - - - -
LHCGIODF_02807 4.61e-66 - - - - - - - -
LHCGIODF_02809 4.03e-10 - - - - - - - -
LHCGIODF_02810 1.15e-67 - - - - - - - -
LHCGIODF_02811 4.92e-154 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LHCGIODF_02812 2.34e-209 - - - K - - - Transcriptional regulator
LHCGIODF_02813 3.68e-130 ywqN - - S - - - NAD(P)H-dependent
LHCGIODF_02815 4.99e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
LHCGIODF_02816 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
LHCGIODF_02817 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LHCGIODF_02818 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LHCGIODF_02819 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
LHCGIODF_02820 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LHCGIODF_02821 1.03e-17 - - - - - - - -
LHCGIODF_02822 1.2e-264 cotH - - M ko:K06330 - ko00000 Spore Coat
LHCGIODF_02823 1.95e-194 cotB - - - ko:K06325 - ko00000 -
LHCGIODF_02824 2.5e-161 ywrJ - - - - - - -
LHCGIODF_02825 4.82e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LHCGIODF_02826 9.64e-218 alsR - - K - - - LysR substrate binding domain
LHCGIODF_02827 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LHCGIODF_02828 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
LHCGIODF_02829 2.15e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
LHCGIODF_02830 1.53e-62 ywsA - - S - - - Protein of unknown function (DUF3892)
LHCGIODF_02831 4.83e-120 batE - - T - - - Sh3 type 3 domain protein
LHCGIODF_02832 2.59e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
LHCGIODF_02833 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LHCGIODF_02834 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LHCGIODF_02835 6.55e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LHCGIODF_02836 6.18e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LHCGIODF_02837 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
LHCGIODF_02838 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
LHCGIODF_02839 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
LHCGIODF_02840 1.1e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LHCGIODF_02841 2.29e-29 ywtC - - - - - - -
LHCGIODF_02842 5.14e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LHCGIODF_02843 3.3e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LHCGIODF_02844 1.67e-176 ywtF_2 - - K - - - Transcriptional regulator
LHCGIODF_02845 1.06e-313 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHCGIODF_02846 1.03e-262 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
LHCGIODF_02847 1.48e-248 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LHCGIODF_02848 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LHCGIODF_02849 4.34e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LHCGIODF_02850 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LHCGIODF_02851 1.5e-257 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LHCGIODF_02852 5.03e-183 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LHCGIODF_02853 2.4e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
LHCGIODF_02854 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LHCGIODF_02855 0.0 tagF2 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LHCGIODF_02858 3.02e-171 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
LHCGIODF_02859 2.7e-204 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LHCGIODF_02860 1.74e-13 - - - L - - - COG2963 Transposase and inactivated derivatives
LHCGIODF_02861 1.64e-204 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LHCGIODF_02862 2.43e-264 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LHCGIODF_02863 4.48e-22 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LHCGIODF_02864 2.52e-40 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LHCGIODF_02865 1.39e-15 - - - - - - - -
LHCGIODF_02866 0.0 lytB - - D - - - Stage II sporulation protein
LHCGIODF_02867 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LHCGIODF_02868 2.13e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LHCGIODF_02869 1.28e-300 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LHCGIODF_02870 4.27e-257 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
LHCGIODF_02871 2.01e-302 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LHCGIODF_02872 9.1e-315 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
LHCGIODF_02873 9.78e-136 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
LHCGIODF_02874 7.68e-174 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LHCGIODF_02875 3.69e-300 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
LHCGIODF_02876 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LHCGIODF_02878 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
LHCGIODF_02879 1.64e-120 - - - M - - - FR47-like protein
LHCGIODF_02880 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
LHCGIODF_02881 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
LHCGIODF_02882 1.95e-109 yuaE - - S - - - DinB superfamily
LHCGIODF_02883 5.8e-137 yuaD - - - - - - -
LHCGIODF_02884 1e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
LHCGIODF_02885 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LHCGIODF_02886 3.39e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
LHCGIODF_02887 5.83e-118 yuaB - - - - - - -
LHCGIODF_02888 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LHCGIODF_02889 3.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
LHCGIODF_02890 3.31e-52 yubF - - S - - - yiaA/B two helix domain
LHCGIODF_02891 2.18e-195 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LHCGIODF_02892 0.0 yubD - - P - - - Major Facilitator Superfamily
LHCGIODF_02893 6.82e-114 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
LHCGIODF_02895 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LHCGIODF_02896 8.95e-255 yubA - - S - - - transporter activity
LHCGIODF_02897 1.45e-232 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LHCGIODF_02898 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
LHCGIODF_02899 2.86e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
LHCGIODF_02900 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LHCGIODF_02901 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LHCGIODF_02902 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
LHCGIODF_02903 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHCGIODF_02904 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHCGIODF_02905 1.2e-297 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHCGIODF_02906 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHCGIODF_02907 2.41e-178 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
LHCGIODF_02908 3.52e-48 - - - - - - - -
LHCGIODF_02909 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
LHCGIODF_02910 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LHCGIODF_02911 5.09e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LHCGIODF_02912 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
LHCGIODF_02913 6.2e-48 - - - - - - - -
LHCGIODF_02914 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
LHCGIODF_02915 2.92e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
LHCGIODF_02916 4.22e-95 yugN - - S - - - YugN-like family
LHCGIODF_02918 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LHCGIODF_02919 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
LHCGIODF_02920 8.16e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
LHCGIODF_02921 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
LHCGIODF_02922 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LHCGIODF_02923 1.56e-254 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
LHCGIODF_02924 6.74e-112 alaR - - K - - - Transcriptional regulator
LHCGIODF_02925 9.89e-201 yugF - - I - - - Hydrolase
LHCGIODF_02926 1.53e-52 yugE - - S - - - Domain of unknown function (DUF1871)
LHCGIODF_02927 9.13e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LHCGIODF_02928 3.04e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_02929 2.49e-91 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
LHCGIODF_02930 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
LHCGIODF_02932 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
LHCGIODF_02933 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
LHCGIODF_02934 1.92e-97 yuxK - - S - - - protein conserved in bacteria
LHCGIODF_02935 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
LHCGIODF_02936 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LHCGIODF_02937 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LHCGIODF_02938 9.13e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
LHCGIODF_02939 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_02940 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LHCGIODF_02941 6.97e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LHCGIODF_02942 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
LHCGIODF_02943 1.73e-22 - - - - - - - -
LHCGIODF_02944 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LHCGIODF_02945 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LHCGIODF_02946 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LHCGIODF_02947 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LHCGIODF_02948 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LHCGIODF_02949 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LHCGIODF_02950 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
LHCGIODF_02951 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
LHCGIODF_02952 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHCGIODF_02953 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_02955 7.01e-183 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
LHCGIODF_02956 6.29e-10 - - - S - - - DegQ (SacQ) family
LHCGIODF_02957 4.38e-09 yuzC - - - - - - -
LHCGIODF_02958 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
LHCGIODF_02959 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LHCGIODF_02960 2.69e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
LHCGIODF_02961 3.11e-87 - - - S - - - Protein of unknown function (DUF1694)
LHCGIODF_02962 1.63e-52 yueH - - S - - - YueH-like protein
LHCGIODF_02963 1.19e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
LHCGIODF_02964 1.35e-244 yueF - - S - - - transporter activity
LHCGIODF_02965 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
LHCGIODF_02966 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
LHCGIODF_02967 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
LHCGIODF_02968 3.53e-170 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHCGIODF_02969 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
LHCGIODF_02970 6.67e-247 yueB - - S - - - type VII secretion protein EsaA
LHCGIODF_02971 1.31e-99 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LHCGIODF_02975 1.87e-107 - - - S - - - Protein of unknown function (DUF3800)
LHCGIODF_02976 1.73e-13 - - - - - - - -
LHCGIODF_02977 3.96e-84 - - - O - - - Papain family cysteine protease
LHCGIODF_02979 1.22e-29 - - - L ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 DNA/RNA non-specific endonuclease
LHCGIODF_02980 3.82e-37 - - - - - - - -
LHCGIODF_02982 8.28e-56 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LHCGIODF_02984 6.74e-30 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
LHCGIODF_02986 2.66e-122 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LHCGIODF_02987 5.98e-72 ypuD - - - - - - -
LHCGIODF_02988 1.39e-258 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LHCGIODF_02989 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
LHCGIODF_02990 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LHCGIODF_02991 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LHCGIODF_02992 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHCGIODF_02993 1.19e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
LHCGIODF_02994 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LHCGIODF_02995 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LHCGIODF_02996 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
LHCGIODF_02997 9.67e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LHCGIODF_02998 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
LHCGIODF_02999 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
LHCGIODF_03000 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LHCGIODF_03001 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LHCGIODF_03002 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
LHCGIODF_03003 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LHCGIODF_03004 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHCGIODF_03005 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_03006 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHCGIODF_03007 1.95e-236 rsiX - - - - - - -
LHCGIODF_03008 4.79e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LHCGIODF_03009 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LHCGIODF_03010 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LHCGIODF_03011 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
LHCGIODF_03012 4.47e-255 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
LHCGIODF_03013 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LHCGIODF_03014 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
LHCGIODF_03015 8.27e-143 ypbE - - M - - - Lysin motif
LHCGIODF_03016 4.08e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
LHCGIODF_03017 6.15e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
LHCGIODF_03018 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LHCGIODF_03019 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LHCGIODF_03020 6.04e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
LHCGIODF_03021 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
LHCGIODF_03022 1.1e-204 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
LHCGIODF_03023 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
LHCGIODF_03024 8.95e-142 ypfA - - M - - - Flagellar protein YcgR
LHCGIODF_03025 2.48e-32 - - - S - - - Family of unknown function (DUF5359)
LHCGIODF_03026 3.91e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LHCGIODF_03027 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LHCGIODF_03028 5.43e-234 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LHCGIODF_03029 1.13e-11 - - - S - - - YpzI-like protein
LHCGIODF_03030 3.87e-134 yphA - - - - - - -
LHCGIODF_03031 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
LHCGIODF_03032 2.06e-38 ypzH - - - - - - -
LHCGIODF_03033 1.72e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LHCGIODF_03034 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LHCGIODF_03035 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
LHCGIODF_03036 4.31e-176 yphF - - - - - - -
LHCGIODF_03037 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LHCGIODF_03038 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LHCGIODF_03039 2.55e-130 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
LHCGIODF_03040 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LHCGIODF_03041 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LHCGIODF_03042 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LHCGIODF_03043 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LHCGIODF_03044 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LHCGIODF_03045 2.13e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
LHCGIODF_03046 5.88e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LHCGIODF_03047 5.72e-263 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LHCGIODF_03048 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LHCGIODF_03049 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LHCGIODF_03050 8.47e-221 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LHCGIODF_03051 4.18e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
LHCGIODF_03052 8.71e-148 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
LHCGIODF_03053 1.81e-292 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LHCGIODF_03054 3.82e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LHCGIODF_03055 3.7e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LHCGIODF_03056 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
LHCGIODF_03057 1.64e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LHCGIODF_03058 3.56e-297 ypiA - - S - - - COG0457 FOG TPR repeat
LHCGIODF_03059 1.83e-129 ypiB - - S - - - Belongs to the UPF0302 family
LHCGIODF_03060 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
LHCGIODF_03061 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
LHCGIODF_03062 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
LHCGIODF_03063 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
LHCGIODF_03064 6.63e-125 ypjA - - S - - - membrane
LHCGIODF_03065 2.79e-182 ypjB - - S - - - sporulation protein
LHCGIODF_03066 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LHCGIODF_03067 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
LHCGIODF_03068 8.25e-63 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LHCGIODF_03069 2.33e-57 - - - - - - - -
LHCGIODF_03070 1.05e-51 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
LHCGIODF_03071 1.68e-82 - - - M - - - nucleic acid phosphodiester bond hydrolysis
LHCGIODF_03073 4.75e-245 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
LHCGIODF_03074 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
LHCGIODF_03075 1.45e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
LHCGIODF_03076 6.72e-41 ydzE - - EG - - - spore germination
LHCGIODF_03077 1.08e-209 - - - K - - - AraC-like ligand binding domain
LHCGIODF_03078 3.37e-222 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LHCGIODF_03079 9.2e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
LHCGIODF_03080 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LHCGIODF_03081 1.27e-275 ydeG - - EGP - - - Major facilitator superfamily
LHCGIODF_03082 3.21e-70 ydeH - - - - - - -
LHCGIODF_03083 5.52e-133 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
LHCGIODF_03084 2.67e-144 - - - - - - - -
LHCGIODF_03085 1.28e-194 ydeK - - EG - - - -transporter
LHCGIODF_03086 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LHCGIODF_03087 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
LHCGIODF_03088 1.56e-131 - - - S ko:K07002 - ko00000 Serine hydrolase
LHCGIODF_03089 1.02e-72 - - - K - - - HxlR-like helix-turn-helix
LHCGIODF_03090 6.56e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LHCGIODF_03091 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
LHCGIODF_03092 7.13e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LHCGIODF_03093 5.44e-189 - - - J - - - GNAT acetyltransferase
LHCGIODF_03094 1.45e-205 - - - EG - - - EamA-like transporter family
LHCGIODF_03095 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LHCGIODF_03096 1.54e-232 - 4.1.1.86 - E ko:K13745 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
LHCGIODF_03097 4.04e-149 ydfE - - S - - - Flavin reductase like domain
LHCGIODF_03098 1.23e-157 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LHCGIODF_03099 3.92e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LHCGIODF_03100 2.77e-251 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_03101 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHCGIODF_03102 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
LHCGIODF_03103 8.25e-218 - - - S - - - Alpha/beta hydrolase family
LHCGIODF_03104 3.77e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LHCGIODF_03105 3.54e-188 - - - K - - - Bacterial transcription activator, effector binding domain
LHCGIODF_03106 5.22e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LHCGIODF_03107 4.7e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
LHCGIODF_03108 1.11e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LHCGIODF_03109 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
LHCGIODF_03110 3.78e-74 ydfQ - - CO - - - Thioredoxin
LHCGIODF_03111 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
LHCGIODF_03112 5.33e-39 - - - - - - - -
LHCGIODF_03114 1.74e-152 ydfR - - S - - - Protein of unknown function (DUF421)
LHCGIODF_03115 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
LHCGIODF_03116 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LHCGIODF_03117 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
LHCGIODF_03118 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
LHCGIODF_03119 2.85e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
LHCGIODF_03120 5.76e-70 - - - S - - - DoxX-like family
LHCGIODF_03121 2.49e-114 yycN - - K - - - Acetyltransferase
LHCGIODF_03122 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
LHCGIODF_03123 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LHCGIODF_03124 1.2e-117 - - - S - - - DinB family
LHCGIODF_03125 2.92e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHCGIODF_03126 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
LHCGIODF_03127 6.42e-147 ydgI - - C - - - nitroreductase
LHCGIODF_03128 3.29e-90 - - - K - - - Winged helix DNA-binding domain
LHCGIODF_03129 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
LHCGIODF_03130 1.02e-154 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
LHCGIODF_03131 4.31e-157 ydhC - - K - - - FCD
LHCGIODF_03132 5.16e-309 ydhD - - M - - - Glycosyl hydrolase
LHCGIODF_03133 3.91e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LHCGIODF_03134 1.43e-161 - - - - - - - -
LHCGIODF_03135 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
LHCGIODF_03136 2.74e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
LHCGIODF_03138 7.65e-108 - - - K - - - Acetyltransferase (GNAT) domain
LHCGIODF_03139 1.56e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LHCGIODF_03140 2.59e-126 ydhK - - M - - - Protein of unknown function (DUF1541)
LHCGIODF_03141 2.56e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
LHCGIODF_03142 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHCGIODF_03143 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHCGIODF_03144 3.76e-304 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHCGIODF_03145 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHCGIODF_03146 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
LHCGIODF_03147 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
LHCGIODF_03148 3.44e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LHCGIODF_03149 2.64e-268 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
LHCGIODF_03150 4.79e-100 ydhU - - P ko:K07217 - ko00000 Catalase
LHCGIODF_03151 7.94e-22 ydhU - - P ko:K07217 - ko00000 Manganese containing catalase
LHCGIODF_03154 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
LHCGIODF_03155 5.26e-88 ywpG - - - - - - -
LHCGIODF_03156 2.53e-88 ywpF - - S - - - YwpF-like protein
LHCGIODF_03157 5.03e-108 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
LHCGIODF_03158 0.0 - - - M - - - cell wall anchor domain
LHCGIODF_03159 4.13e-222 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
LHCGIODF_03160 0.0 ywpD - - T - - - Histidine kinase
LHCGIODF_03161 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LHCGIODF_03162 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LHCGIODF_03163 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
LHCGIODF_03164 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LHCGIODF_03165 9.79e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LHCGIODF_03166 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
LHCGIODF_03167 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
LHCGIODF_03168 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
LHCGIODF_03169 5.56e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LHCGIODF_03170 1.19e-311 ywoF - - P - - - Right handed beta helix region
LHCGIODF_03171 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
LHCGIODF_03172 8.92e-306 ywoD - - EGP - - - Major facilitator superfamily
LHCGIODF_03173 2.56e-134 yjgF - - Q - - - Isochorismatase family
LHCGIODF_03174 2.4e-101 - - - - - - - -
LHCGIODF_03175 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
LHCGIODF_03176 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
LHCGIODF_03177 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
LHCGIODF_03178 4.49e-93 ywnJ - - S - - - VanZ like family
LHCGIODF_03179 2.63e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LHCGIODF_03180 3.65e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
LHCGIODF_03181 6.95e-21 ywnC - - S - - - Family of unknown function (DUF5362)
LHCGIODF_03182 4.73e-234 - - - M - - - NeuB family
LHCGIODF_03183 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
LHCGIODF_03184 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LHCGIODF_03185 4.46e-180 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
LHCGIODF_03186 1.24e-77 ywnC - - S - - - Family of unknown function (DUF5362)
LHCGIODF_03187 1.69e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
LHCGIODF_03188 4.58e-85 ywnA - - K - - - Transcriptional regulator
LHCGIODF_03189 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LHCGIODF_03190 3.2e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
LHCGIODF_03191 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
LHCGIODF_03192 5.51e-28 - - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
LHCGIODF_03193 1.11e-21 csbD - - K - - - CsbD-like
LHCGIODF_03194 7.7e-110 ywmF - - S - - - Peptidase M50
LHCGIODF_03196 3.1e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LHCGIODF_03197 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LHCGIODF_03198 5.24e-186 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LHCGIODF_03200 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LHCGIODF_03201 1.56e-156 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LHCGIODF_03202 1.97e-233 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
LHCGIODF_03203 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LHCGIODF_03204 8.01e-173 ywmB - - S - - - TATA-box binding
LHCGIODF_03205 4.54e-45 ywzB - - S - - - membrane
LHCGIODF_03206 1.76e-114 ywmA - - - - - - -
LHCGIODF_03207 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LHCGIODF_03208 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LHCGIODF_03209 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LHCGIODF_03210 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LHCGIODF_03211 7.94e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LHCGIODF_03212 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LHCGIODF_03213 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LHCGIODF_03214 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LHCGIODF_03215 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
LHCGIODF_03216 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LHCGIODF_03217 5.09e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LHCGIODF_03218 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
LHCGIODF_03219 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
LHCGIODF_03220 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LHCGIODF_03221 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
LHCGIODF_03222 8.25e-248 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LHCGIODF_03223 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
LHCGIODF_03224 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
LHCGIODF_03225 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LHCGIODF_03227 8.46e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LHCGIODF_03228 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LHCGIODF_03229 6.62e-87 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHCGIODF_03230 2.93e-108 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LHCGIODF_03231 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
LHCGIODF_03232 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LHCGIODF_03233 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LHCGIODF_03234 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
LHCGIODF_03235 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
LHCGIODF_03236 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LHCGIODF_03237 8.72e-297 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
LHCGIODF_03238 8.04e-230 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LHCGIODF_03239 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LHCGIODF_03240 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
LHCGIODF_03241 2.72e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LHCGIODF_03242 2.38e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LHCGIODF_03243 4.26e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LHCGIODF_03244 1.51e-196 - - - S - - - Domain of Unknown Function (DUF1206)
LHCGIODF_03245 2.21e-255 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
LHCGIODF_03246 1.33e-310 yxeQ - - S - - - MmgE/PrpD family
LHCGIODF_03247 3.37e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
LHCGIODF_03248 6.82e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_03249 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LHCGIODF_03250 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LHCGIODF_03251 2.19e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHCGIODF_03252 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHCGIODF_03253 2.61e-235 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
LHCGIODF_03254 2.71e-192 yxeH - - S - - - hydrolases of the HAD superfamily
LHCGIODF_03257 7.32e-42 yxeE - - - - - - -
LHCGIODF_03258 7.57e-28 yxeD - - - - - - -
LHCGIODF_03259 9.65e-91 - - - - - - - -
LHCGIODF_03260 9.65e-223 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHCGIODF_03261 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
LHCGIODF_03262 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LHCGIODF_03263 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_03264 4.47e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_03265 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHCGIODF_03266 2.83e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LHCGIODF_03267 3.26e-193 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LHCGIODF_03268 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
LHCGIODF_03269 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LHCGIODF_03270 4.19e-298 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
LHCGIODF_03271 4.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LHCGIODF_03272 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LHCGIODF_03273 1.23e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LHCGIODF_03274 4.9e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LHCGIODF_03275 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LHCGIODF_03276 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LHCGIODF_03277 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
LHCGIODF_03279 1.23e-63 yxcD - - S - - - Protein of unknown function (DUF2653)
LHCGIODF_03280 4.16e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHCGIODF_03281 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
LHCGIODF_03283 8.38e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LHCGIODF_03284 1.03e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
LHCGIODF_03285 2.4e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LHCGIODF_03286 1.79e-43 yxaI - - S - - - membrane protein domain
LHCGIODF_03287 4.24e-78 - - - S - - - Family of unknown function (DUF5391)
LHCGIODF_03288 2.49e-31 yxaI - - S - - - membrane protein domain
LHCGIODF_03289 8.75e-51 yxaI - - S - - - membrane protein domain
LHCGIODF_03290 4.89e-282 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
LHCGIODF_03291 3.65e-251 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
LHCGIODF_03292 9.61e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LHCGIODF_03293 1.5e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LHCGIODF_03294 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHCGIODF_03295 5.96e-77 - - - S ko:K06518 - ko00000,ko02000 LrgA family
LHCGIODF_03296 5.16e-152 yxaC - - M - - - effector of murein hydrolase
LHCGIODF_03297 2.01e-242 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
LHCGIODF_03298 1.35e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LHCGIODF_03299 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
LHCGIODF_03300 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LHCGIODF_03301 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
LHCGIODF_03302 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LHCGIODF_03303 1.41e-266 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
LHCGIODF_03304 1.76e-277 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LHCGIODF_03305 1.98e-233 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LHCGIODF_03306 5.66e-193 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LHCGIODF_03307 5.47e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LHCGIODF_03308 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LHCGIODF_03309 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LHCGIODF_03310 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
LHCGIODF_03311 2.66e-102 ypmB - - S - - - protein conserved in bacteria
LHCGIODF_03312 2.53e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LHCGIODF_03313 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
LHCGIODF_03314 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
LHCGIODF_03315 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LHCGIODF_03316 2.37e-120 ypoC - - - - - - -
LHCGIODF_03317 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LHCGIODF_03318 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LHCGIODF_03319 6.93e-236 yppC - - S - - - Protein of unknown function (DUF2515)
LHCGIODF_03322 1.42e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
LHCGIODF_03323 9.21e-11 - - - S - - - YppF-like protein
LHCGIODF_03324 8.72e-68 yppG - - S - - - YppG-like protein
LHCGIODF_03325 1.19e-92 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LHCGIODF_03326 2.13e-109 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
LHCGIODF_03327 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LHCGIODF_03328 1.7e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
LHCGIODF_03329 9.4e-128 ypsA - - S - - - Belongs to the UPF0398 family
LHCGIODF_03330 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LHCGIODF_03331 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LHCGIODF_03333 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
LHCGIODF_03334 1.88e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHCGIODF_03335 1.2e-202 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LHCGIODF_03336 3.18e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
LHCGIODF_03337 5.71e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
LHCGIODF_03338 1.2e-131 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
LHCGIODF_03339 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
LHCGIODF_03340 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LHCGIODF_03341 1.11e-126 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LHCGIODF_03342 1e-290 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
LHCGIODF_03343 2.63e-265 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
LHCGIODF_03344 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
LHCGIODF_03345 0.0 ypbR - - S - - - Dynamin family
LHCGIODF_03346 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
LHCGIODF_03347 1.08e-11 - - - - - - - -
LHCGIODF_03348 2.26e-213 ypcP - - L - - - 5'3' exonuclease
LHCGIODF_03349 5.23e-05 - - - - ko:K06429 - ko00000 -
LHCGIODF_03350 1.6e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
LHCGIODF_03351 5.2e-156 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LHCGIODF_03352 2.31e-162 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
LHCGIODF_03353 1.54e-37 ypeQ - - S - - - Zinc-finger
LHCGIODF_03354 1.23e-39 - - - S - - - Protein of unknown function (DUF2564)
LHCGIODF_03355 1.17e-22 degR - - - - - - -
LHCGIODF_03356 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
LHCGIODF_03357 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LHCGIODF_03358 6.09e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LHCGIODF_03359 3.66e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
LHCGIODF_03360 2.94e-141 yagB - - S ko:K06950 - ko00000 phosphohydrolase
LHCGIODF_03361 4.02e-204 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
LHCGIODF_03362 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
LHCGIODF_03363 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
LHCGIODF_03364 1.19e-184 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
LHCGIODF_03365 1.41e-147 ypjP - - S - - - YpjP-like protein
LHCGIODF_03366 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
LHCGIODF_03367 7.88e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LHCGIODF_03368 2.24e-141 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LHCGIODF_03369 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
LHCGIODF_03370 1.4e-236 yplP - - K - - - Transcriptional regulator
LHCGIODF_03371 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LHCGIODF_03372 6.71e-241 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LHCGIODF_03373 9.8e-313 yoeA - - V - - - MATE efflux family protein
LHCGIODF_03374 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
LHCGIODF_03376 1.14e-124 - - - L - - - Integrase
LHCGIODF_03377 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
LHCGIODF_03378 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LHCGIODF_03379 2.41e-198 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_03380 1.63e-234 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LHCGIODF_03381 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LHCGIODF_03382 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
LHCGIODF_03383 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_03384 3.04e-258 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LHCGIODF_03385 2.24e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LHCGIODF_03386 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LHCGIODF_03387 2.28e-159 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHCGIODF_03388 5.68e-53 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
LHCGIODF_03389 4.25e-173 yoxB - - - - - - -
LHCGIODF_03390 2.06e-106 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LHCGIODF_03391 2.24e-300 yoaB - - EGP - - - the major facilitator superfamily
LHCGIODF_03392 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
LHCGIODF_03393 9.23e-232 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LHCGIODF_03394 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LHCGIODF_03395 1.03e-44 yoaF - - - - - - -
LHCGIODF_03397 1.46e-19 - - - - - - - -
LHCGIODF_03398 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
LHCGIODF_03399 2.74e-283 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
LHCGIODF_03400 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
LHCGIODF_03401 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
LHCGIODF_03402 1.79e-145 yoaK - - S - - - Membrane
LHCGIODF_03403 9.68e-251 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
LHCGIODF_03404 1.7e-169 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
LHCGIODF_03407 4.41e-293 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LHCGIODF_03409 2.09e-110 - - - - - - - -
LHCGIODF_03410 1.04e-217 yoaR - - V - - - vancomycin resistance protein
LHCGIODF_03411 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
LHCGIODF_03412 1.21e-40 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_03413 1.63e-190 yoaT - - S - - - Protein of unknown function (DUF817)
LHCGIODF_03414 5.48e-202 yoaU - - K - - - LysR substrate binding domain
LHCGIODF_03415 1.11e-202 yoaV - - EG - - - EamA-like transporter family
LHCGIODF_03416 1.4e-42 yoaW - - - - - - -
LHCGIODF_03417 3.55e-47 yoaW - - - - - - -
LHCGIODF_03418 2.07e-148 lin0465 - - S - - - DJ-1/PfpI family
LHCGIODF_03419 2.54e-215 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
LHCGIODF_03422 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
LHCGIODF_03423 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
LHCGIODF_03424 2.11e-49 - - - S - - - TM2 domain
LHCGIODF_03426 2.49e-43 yoaF - - - - - - -
LHCGIODF_03427 1.38e-172 - - - - - - - -
LHCGIODF_03428 1.15e-22 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
LHCGIODF_03429 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
LHCGIODF_03430 3.38e-73 ygzB - - S - - - UPF0295 protein
LHCGIODF_03431 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LHCGIODF_03432 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
LHCGIODF_03433 1.33e-311 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LHCGIODF_03434 1.87e-238 ygaE - - S - - - Membrane
LHCGIODF_03435 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
LHCGIODF_03436 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
LHCGIODF_03437 8.19e-49 ygaB - - S - - - YgaB-like protein
LHCGIODF_03438 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
LHCGIODF_03439 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHCGIODF_03440 1.73e-48 yfhS - - - - - - -
LHCGIODF_03441 1.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
LHCGIODF_03442 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
LHCGIODF_03443 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
LHCGIODF_03444 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LHCGIODF_03445 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
LHCGIODF_03446 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
LHCGIODF_03447 1.91e-114 yfhK - - T - - - Bacterial SH3 domain homologues
LHCGIODF_03448 8.95e-60 yfhJ - - S - - - WVELL protein
LHCGIODF_03449 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
LHCGIODF_03450 2.45e-268 yfhI - - EGP - - - -transporter
LHCGIODF_03452 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
LHCGIODF_03453 9.32e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
LHCGIODF_03454 8.92e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
LHCGIODF_03456 8.86e-35 yfhD - - S - - - YfhD-like protein
LHCGIODF_03457 1.66e-137 yfhC - - C - - - nitroreductase
LHCGIODF_03458 1.26e-213 yfhB - - S - - - PhzF family
LHCGIODF_03459 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHCGIODF_03460 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHCGIODF_03461 3.83e-231 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LHCGIODF_03462 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LHCGIODF_03463 2.11e-103 yfiV - - K - - - transcriptional
LHCGIODF_03464 0.0 yfiU - - EGP - - - the major facilitator superfamily
LHCGIODF_03465 1.15e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
LHCGIODF_03466 2.54e-271 yfiS - - EGP - - - Major facilitator superfamily
LHCGIODF_03467 1.34e-137 yfiR - - K - - - Transcriptional regulator
LHCGIODF_03468 1.33e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LHCGIODF_03469 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
LHCGIODF_03470 1.89e-128 padR - - K - - - transcriptional
LHCGIODF_03471 4.19e-263 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LHCGIODF_03472 1.78e-265 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LHCGIODF_03473 5.1e-213 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_03474 1.01e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
LHCGIODF_03475 4.15e-240 baeS - - T - - - Histidine kinase
LHCGIODF_03476 2e-206 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
LHCGIODF_03477 2.01e-84 yfiD3 - - S - - - DoxX
LHCGIODF_03478 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LHCGIODF_03479 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
LHCGIODF_03480 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
LHCGIODF_03481 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHCGIODF_03482 8.69e-181 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
LHCGIODF_03483 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LHCGIODF_03486 4.94e-88 - - - S - - - LXG domain of WXG superfamily
LHCGIODF_03488 3.31e-214 yocS - - S ko:K03453 - ko00000 -transporter
LHCGIODF_03489 2.59e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LHCGIODF_03490 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LHCGIODF_03491 0.0 yojO - - P - - - Von Willebrand factor
LHCGIODF_03492 1.55e-206 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
LHCGIODF_03493 1.04e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LHCGIODF_03494 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LHCGIODF_03495 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
LHCGIODF_03496 3.54e-140 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LHCGIODF_03498 1.69e-312 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
LHCGIODF_03499 1.44e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LHCGIODF_03500 3.71e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
LHCGIODF_03501 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
LHCGIODF_03502 1.52e-57 - - - - - - - -
LHCGIODF_03503 2.33e-207 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
LHCGIODF_03504 8.34e-104 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
LHCGIODF_03505 1.95e-14 - - - - - - - -
LHCGIODF_03506 1.31e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
LHCGIODF_03507 5.64e-84 iolK - - S - - - tautomerase
LHCGIODF_03508 2.63e-73 yodB - - K - - - transcriptional
LHCGIODF_03509 4.53e-139 yodC - - C - - - nitroreductase
LHCGIODF_03510 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
LHCGIODF_03511 8.09e-215 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LHCGIODF_03512 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
LHCGIODF_03513 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LHCGIODF_03514 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LHCGIODF_03515 1.24e-165 yodH - - Q - - - Methyltransferase
LHCGIODF_03516 4.86e-41 yodI - - - - - - -
LHCGIODF_03517 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
LHCGIODF_03518 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
LHCGIODF_03519 2.08e-12 - - - - - - - -
LHCGIODF_03520 1.17e-71 yodL - - S - - - YodL-like
LHCGIODF_03521 1.35e-136 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LHCGIODF_03522 5.18e-34 yozD - - S - - - YozD-like protein
LHCGIODF_03524 7.44e-159 yodN - - - - - - -
LHCGIODF_03525 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
LHCGIODF_03526 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
LHCGIODF_03527 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
LHCGIODF_03528 2.15e-196 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
LHCGIODF_03529 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
LHCGIODF_03530 3.85e-152 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LHCGIODF_03531 1.62e-159 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LHCGIODF_03532 3.85e-314 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LHCGIODF_03533 2.81e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
LHCGIODF_03534 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
LHCGIODF_03535 9.12e-13 cgeC - - - ko:K06321 - ko00000 -
LHCGIODF_03536 9.46e-29 cgeC - - - ko:K06321 - ko00000 -
LHCGIODF_03537 1.79e-82 cgeA - - - ko:K06319 - ko00000 -
LHCGIODF_03538 2.69e-227 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
LHCGIODF_03539 9.41e-279 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
LHCGIODF_03540 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LHCGIODF_03541 4.13e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LHCGIODF_03542 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LHCGIODF_03543 4.14e-94 ypoP - - K - - - transcriptional
LHCGIODF_03544 9.99e-290 mepA - - V - - - MATE efflux family protein
LHCGIODF_03545 8.69e-40 ypmT - - S - - - Uncharacterized ympT
LHCGIODF_03546 1.95e-128 ypmS - - S - - - protein conserved in bacteria
LHCGIODF_03547 1.82e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
LHCGIODF_03548 7.93e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LHCGIODF_03549 2.12e-53 ypmP - - S - - - Protein of unknown function (DUF2535)
LHCGIODF_03550 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LHCGIODF_03551 2.67e-308 cimH - - C - - - COG3493 Na citrate symporter
LHCGIODF_03552 0.0 - - - O - - - Peptidase family M48
LHCGIODF_03554 5.28e-199 yxkH - - G - - - Polysaccharide deacetylase
LHCGIODF_03555 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHCGIODF_03556 1.58e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
LHCGIODF_03557 1.64e-166 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LHCGIODF_03558 8.4e-133 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LHCGIODF_03559 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LHCGIODF_03560 1.74e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LHCGIODF_03561 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
LHCGIODF_03562 2.09e-244 - - - T - - - Signal transduction histidine kinase
LHCGIODF_03563 1.23e-144 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
LHCGIODF_03564 1.83e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LHCGIODF_03566 4.98e-112 yxjI - - S - - - LURP-one-related
LHCGIODF_03567 2.48e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LHCGIODF_03568 1.49e-273 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LHCGIODF_03569 2.77e-174 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LHCGIODF_03570 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LHCGIODF_03571 4.46e-166 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LHCGIODF_03572 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
LHCGIODF_03573 1.63e-199 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
LHCGIODF_03574 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LHCGIODF_03575 1.47e-133 - - - T - - - Domain of unknown function (DUF4163)
LHCGIODF_03576 6.3e-61 yxiS - - - - - - -
LHCGIODF_03577 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LHCGIODF_03578 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LHCGIODF_03579 2.07e-182 bglS - - M - - - licheninase activity
LHCGIODF_03580 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LHCGIODF_03581 5.32e-143 - - - - - - - -
LHCGIODF_03582 3.8e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
LHCGIODF_03583 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LHCGIODF_03584 6.52e-270 - - - E - - - GDSL-like Lipase/Acylhydrolase
LHCGIODF_03587 3.48e-59 yxiJ - - S - - - YxiJ-like protein
LHCGIODF_03590 7.33e-43 - - - - - - - -
LHCGIODF_03591 4.1e-111 yxiI - - S - - - Protein of unknown function (DUF2716)
LHCGIODF_03592 2.41e-173 - - - - - - - -
LHCGIODF_03595 6.09e-50 - - - S - - - Protein of unknown function (DUF2750)
LHCGIODF_03596 3.95e-67 yxxG - - - - - - -
LHCGIODF_03597 1.9e-88 yxiG - - - - - - -
LHCGIODF_03598 3.76e-66 - - - - - - - -
LHCGIODF_03599 3.53e-100 - - - - - - - -
LHCGIODF_03600 8.9e-119 - - - S - - - Protein of unknown function (DUF4240)
LHCGIODF_03601 8.76e-176 - - - - - - - -
LHCGIODF_03604 5.46e-101 wapA - - M - - - COG3209 Rhs family protein
LHCGIODF_03605 9.58e-13 yxiJ - - S - - - YxiJ-like protein
LHCGIODF_03606 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
LHCGIODF_03607 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
LHCGIODF_03608 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
LHCGIODF_03609 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
LHCGIODF_03610 3.95e-59 yhcC - - - - - - -
LHCGIODF_03611 4.14e-69 - - - - - - - -
LHCGIODF_03612 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_03613 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_03614 3.59e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_03615 1.99e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LHCGIODF_03616 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
LHCGIODF_03617 9.06e-194 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LHCGIODF_03618 3.36e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
LHCGIODF_03619 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LHCGIODF_03620 9.8e-114 - - - S - - - Protein of unknown function (DUF2812)
LHCGIODF_03621 3.22e-65 - - - K - - - Transcriptional regulator PadR-like family
LHCGIODF_03622 1.09e-61 yhcM - - - - - - -
LHCGIODF_03623 8.53e-104 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LHCGIODF_03624 5.17e-223 yhcP - - - - - - -
LHCGIODF_03625 2.39e-146 yhcQ - - M - - - Spore coat protein
LHCGIODF_03626 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LHCGIODF_03627 5.1e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
LHCGIODF_03628 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LHCGIODF_03629 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
LHCGIODF_03630 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
LHCGIODF_03631 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
LHCGIODF_03632 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LHCGIODF_03633 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LHCGIODF_03634 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LHCGIODF_03635 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LHCGIODF_03636 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LHCGIODF_03637 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LHCGIODF_03638 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
LHCGIODF_03639 8.92e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_03640 5.44e-144 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHCGIODF_03641 1.1e-114 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
LHCGIODF_03642 1.65e-51 yhdB - - S - - - YhdB-like protein
LHCGIODF_03643 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
LHCGIODF_03644 4.84e-275 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LHCGIODF_03645 1.37e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
LHCGIODF_03646 4.33e-306 ygxB - - M - - - Conserved TM helix
LHCGIODF_03647 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
LHCGIODF_03648 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
LHCGIODF_03649 1.45e-203 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LHCGIODF_03650 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_03651 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
LHCGIODF_03652 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
LHCGIODF_03653 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LHCGIODF_03654 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
LHCGIODF_03655 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LHCGIODF_03656 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LHCGIODF_03657 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
LHCGIODF_03658 4.29e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LHCGIODF_03659 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LHCGIODF_03660 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LHCGIODF_03661 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
LHCGIODF_03662 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LHCGIODF_03663 2.04e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LHCGIODF_03664 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHCGIODF_03665 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
LHCGIODF_03666 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
LHCGIODF_03667 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LHCGIODF_03668 1.19e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LHCGIODF_03669 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LHCGIODF_03670 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LHCGIODF_03671 5.72e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LHCGIODF_03672 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LHCGIODF_03673 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LHCGIODF_03674 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHCGIODF_03675 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHCGIODF_03676 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
LHCGIODF_03677 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LHCGIODF_03678 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LHCGIODF_03679 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LHCGIODF_03680 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LHCGIODF_03681 2.13e-229 ybaC - - S - - - Alpha/beta hydrolase family
LHCGIODF_03682 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LHCGIODF_03683 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LHCGIODF_03684 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LHCGIODF_03685 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LHCGIODF_03686 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LHCGIODF_03687 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LHCGIODF_03688 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LHCGIODF_03689 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LHCGIODF_03690 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LHCGIODF_03691 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LHCGIODF_03692 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LHCGIODF_03693 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LHCGIODF_03694 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LHCGIODF_03695 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LHCGIODF_03696 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LHCGIODF_03697 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LHCGIODF_03698 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LHCGIODF_03699 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LHCGIODF_03700 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LHCGIODF_03701 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LHCGIODF_03702 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LHCGIODF_03703 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LHCGIODF_03704 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LHCGIODF_03705 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
LHCGIODF_03706 5.57e-276 yabE - - T - - - protein conserved in bacteria
LHCGIODF_03707 2.03e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LHCGIODF_03708 2.05e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LHCGIODF_03709 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
LHCGIODF_03710 5.32e-53 veg - - S - - - protein conserved in bacteria
LHCGIODF_03711 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LHCGIODF_03712 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LHCGIODF_03713 1.4e-82 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
LHCGIODF_03714 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LHCGIODF_03715 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LHCGIODF_03716 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LHCGIODF_03717 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LHCGIODF_03718 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LHCGIODF_03719 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
LHCGIODF_03720 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LHCGIODF_03721 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
LHCGIODF_03722 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LHCGIODF_03723 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LHCGIODF_03724 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LHCGIODF_03725 1.91e-66 yabP - - S - - - Sporulation protein YabP
LHCGIODF_03726 1.49e-137 yabQ - - S - - - spore cortex biosynthesis protein
LHCGIODF_03727 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LHCGIODF_03728 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LHCGIODF_03731 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
LHCGIODF_03732 1.61e-167 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LHCGIODF_03733 1.2e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
LHCGIODF_03734 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LHCGIODF_03735 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
LHCGIODF_03736 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LHCGIODF_03737 8.08e-188 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LHCGIODF_03738 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LHCGIODF_03739 2.07e-205 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
LHCGIODF_03740 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LHCGIODF_03741 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LHCGIODF_03742 4.92e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
LHCGIODF_03743 1.32e-215 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
LHCGIODF_03744 1.11e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LHCGIODF_03745 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LHCGIODF_03746 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LHCGIODF_03747 1.81e-41 yazB - - K - - - transcriptional
LHCGIODF_03748 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LHCGIODF_03749 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LHCGIODF_03750 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
LHCGIODF_03751 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
LHCGIODF_03752 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
LHCGIODF_03753 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
LHCGIODF_03754 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
LHCGIODF_03755 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
LHCGIODF_03756 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
LHCGIODF_03757 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHCGIODF_03758 1.37e-99 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LHCGIODF_03759 3e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
LHCGIODF_03760 2.37e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LHCGIODF_03761 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LHCGIODF_03762 6.8e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
LHCGIODF_03763 1.86e-212 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
LHCGIODF_03764 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
LHCGIODF_03765 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LHCGIODF_03766 2.78e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LHCGIODF_03767 7.27e-42 yqkK - - - - - - -
LHCGIODF_03768 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LHCGIODF_03769 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LHCGIODF_03770 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
LHCGIODF_03771 7.23e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
LHCGIODF_03772 3.18e-77 ansR - - K - - - Transcriptional regulator
LHCGIODF_03773 1.19e-279 yqxK - - L - - - DNA helicase
LHCGIODF_03774 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
LHCGIODF_03775 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
LHCGIODF_03776 1.04e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
LHCGIODF_03777 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
LHCGIODF_03778 5.61e-221 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LHCGIODF_03779 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
LHCGIODF_03780 1.25e-72 yqkB - - S - - - Belongs to the HesB IscA family
LHCGIODF_03781 2.28e-248 yqkA - - K - - - GrpB protein
LHCGIODF_03782 2.25e-78 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
LHCGIODF_03783 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
LHCGIODF_03784 3.23e-66 yqiX - - S - - - YolD-like protein
LHCGIODF_03785 1.46e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LHCGIODF_03787 7.96e-287 yqjV - - G - - - Major Facilitator Superfamily
LHCGIODF_03789 5.43e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHCGIODF_03790 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LHCGIODF_03791 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
LHCGIODF_03792 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHCGIODF_03793 5.2e-226 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LHCGIODF_03794 1.96e-189 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LHCGIODF_03795 0.0 rocB - - E - - - arginine degradation protein
LHCGIODF_03796 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LHCGIODF_03797 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LHCGIODF_03798 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LHCGIODF_03799 2.2e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LHCGIODF_03800 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LHCGIODF_03801 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LHCGIODF_03802 4.76e-269 ybdO - - S - - - Domain of unknown function (DUF4885)
LHCGIODF_03803 1.05e-192 ybdN - - - - - - -
LHCGIODF_03804 1.14e-177 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
LHCGIODF_03806 9.98e-75 - - - - - - - -
LHCGIODF_03807 6.59e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
LHCGIODF_03808 3.85e-66 - - - K - - - Helix-turn-helix domain
LHCGIODF_03809 7.26e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
LHCGIODF_03810 1.6e-63 - - - - - - - -
LHCGIODF_03812 2.32e-119 ybcF - - P - - - carbonic anhydrase
LHCGIODF_03813 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
LHCGIODF_03814 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LHCGIODF_03815 4.32e-126 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LHCGIODF_03816 6.9e-77 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
LHCGIODF_03817 3.67e-227 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LHCGIODF_03818 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LHCGIODF_03819 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LHCGIODF_03820 8.33e-290 ybbR - - S - - - protein conserved in bacteria
LHCGIODF_03821 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LHCGIODF_03822 1.3e-150 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LHCGIODF_03823 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHCGIODF_03829 2.43e-100 ybbK - - S - - - Protein of unknown function (DUF523)
LHCGIODF_03830 3.13e-114 ybbJ - - J - - - acetyltransferase
LHCGIODF_03831 4.52e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LHCGIODF_03832 1.1e-193 ybbH - - K - - - transcriptional
LHCGIODF_03833 2.09e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHCGIODF_03834 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
LHCGIODF_03835 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
LHCGIODF_03836 8.49e-305 ybbC - - S - - - protein conserved in bacteria
LHCGIODF_03837 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
LHCGIODF_03838 2.54e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
LHCGIODF_03839 1.17e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHCGIODF_03840 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHCGIODF_03841 7.15e-178 ybbA - - S ko:K07017 - ko00000 Putative esterase
LHCGIODF_03842 7.61e-203 ybaS - - S - - - Na -dependent transporter
LHCGIODF_03844 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LHCGIODF_03845 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LHCGIODF_03846 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LHCGIODF_03847 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LHCGIODF_03848 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
LHCGIODF_03849 2.59e-312 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LHCGIODF_03850 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LHCGIODF_03851 3.62e-215 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
LHCGIODF_03852 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LHCGIODF_03853 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LHCGIODF_03854 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
LHCGIODF_03855 0.0 ylqG - - - - - - -
LHCGIODF_03856 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LHCGIODF_03857 2.83e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LHCGIODF_03858 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LHCGIODF_03859 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LHCGIODF_03860 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LHCGIODF_03861 9.77e-80 ylqD - - S - - - YlqD protein
LHCGIODF_03862 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LHCGIODF_03863 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LHCGIODF_03864 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LHCGIODF_03865 8.01e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LHCGIODF_03866 1.67e-114 - - - - - - - -
LHCGIODF_03867 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LHCGIODF_03868 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LHCGIODF_03869 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LHCGIODF_03870 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LHCGIODF_03871 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LHCGIODF_03872 4.39e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LHCGIODF_03873 3.39e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LHCGIODF_03874 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LHCGIODF_03875 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LHCGIODF_03876 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LHCGIODF_03877 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LHCGIODF_03878 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
LHCGIODF_03879 3.65e-78 yloU - - S - - - protein conserved in bacteria
LHCGIODF_03880 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LHCGIODF_03881 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LHCGIODF_03882 9.44e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LHCGIODF_03883 4.57e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LHCGIODF_03884 1.76e-194 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LHCGIODF_03885 2.3e-294 - - - S - - - damaged DNA binding
LHCGIODF_03886 9.74e-67 - - - S - - - YolD-like protein
LHCGIODF_03887 9.73e-49 - - - - - - - -
LHCGIODF_03889 1.76e-126 - - - J - - - Acetyltransferase (GNAT) domain
LHCGIODF_03890 1.65e-127 yokK - - S - - - SMI1 / KNR4 family
LHCGIODF_03891 1.66e-52 - - - S - - - SMI1-KNR4 cell-wall
LHCGIODF_03892 6.69e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LHCGIODF_03893 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LHCGIODF_03894 1.12e-115 yokH - - G - - - SMI1 / KNR4 family
LHCGIODF_03895 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
LHCGIODF_03896 5.01e-69 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
LHCGIODF_03897 2.39e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
LHCGIODF_03898 5.06e-181 - - - J - - - FR47-like protein
LHCGIODF_03899 1.26e-126 yobS - - K - - - Transcriptional regulator
LHCGIODF_03900 4.49e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LHCGIODF_03901 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
LHCGIODF_03902 1.37e-220 yobV - - K - - - WYL domain
LHCGIODF_03903 5.2e-121 yobW - - - - - - -
LHCGIODF_03904 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
LHCGIODF_03905 9.39e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LHCGIODF_03906 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
LHCGIODF_03907 6.12e-184 - - - - - - - -
LHCGIODF_03908 1.32e-122 yocC - - - - - - -
LHCGIODF_03909 6.44e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
LHCGIODF_03910 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
LHCGIODF_03911 4.09e-251 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHCGIODF_03912 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHCGIODF_03913 6.78e-174 yocH - - M - - - COG1388 FOG LysM repeat
LHCGIODF_03914 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LHCGIODF_03915 5.95e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LHCGIODF_03916 1.42e-107 yocK - - T - - - general stress protein
LHCGIODF_03917 3.02e-70 yocL - - - - - - -
LHCGIODF_03918 2.02e-43 - - - - - - - -
LHCGIODF_03919 2.69e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LHCGIODF_03920 2.94e-55 yozN - - - - - - -
LHCGIODF_03921 1.83e-49 yocN - - - - - - -
LHCGIODF_03922 2.17e-74 yozO - - S - - - Bacterial PH domain
LHCGIODF_03923 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
LHCGIODF_03924 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LHCGIODF_03925 1.08e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
LHCGIODF_03926 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LHCGIODF_03927 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
LHCGIODF_03928 8.34e-149 ytfI - - S - - - Protein of unknown function (DUF2953)
LHCGIODF_03929 1.37e-110 yteJ - - S - - - RDD family
LHCGIODF_03930 9.73e-230 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
LHCGIODF_03931 8.38e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LHCGIODF_03932 0.0 ytcJ - - S - - - amidohydrolase
LHCGIODF_03933 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LHCGIODF_03934 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
LHCGIODF_03935 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LHCGIODF_03936 1.3e-264 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LHCGIODF_03937 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LHCGIODF_03938 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LHCGIODF_03939 5.29e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LHCGIODF_03940 4.87e-141 yttP - - K - - - Transcriptional regulator
LHCGIODF_03941 3.24e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LHCGIODF_03942 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
LHCGIODF_03943 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LHCGIODF_03944 2.47e-08 - - - - - - - -
LHCGIODF_03948 1.94e-137 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LHCGIODF_03949 4.91e-235 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
LHCGIODF_03950 1.47e-85 - - - S - - - Immunity protein 70
LHCGIODF_03951 1.13e-144 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LHCGIODF_03952 1.54e-75 - - - S - - - Bacteriophage holin family
LHCGIODF_03955 1.93e-246 - - - S - - - Domain of unknown function (DUF2479)
LHCGIODF_03956 5.65e-134 - - - - - - - -
LHCGIODF_03957 2.88e-277 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
LHCGIODF_03958 1.19e-135 - - - S - - - Phage tail protein
LHCGIODF_03959 0.0 - - - D - - - phage tail tape measure protein
LHCGIODF_03962 2.65e-100 - - - S - - - Phage tail tube protein
LHCGIODF_03964 1.19e-66 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LHCGIODF_03965 2.13e-51 - - - S - - - Phage head-tail joining protein
LHCGIODF_03966 1.4e-50 - - - S - - - Phage gp6-like head-tail connector protein
LHCGIODF_03967 1.89e-34 - - - - - - - -
LHCGIODF_03968 1.06e-266 - - - S - - - capsid protein
LHCGIODF_03969 6.14e-151 - - - OU - - - Belongs to the peptidase S14 family
LHCGIODF_03970 2.64e-303 - - - S - - - Phage portal protein
LHCGIODF_03972 0.0 - - - S - - - Terminase
LHCGIODF_03973 6.85e-103 - - - L - - - phage terminase small subunit
LHCGIODF_03974 6.88e-66 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
LHCGIODF_03976 5.07e-14 - - - - - - - -
LHCGIODF_03984 0.0 wapA - - M - - - COG3209 Rhs family protein
LHCGIODF_03985 2.94e-210 yxxF - - EG - - - EamA-like transporter family
LHCGIODF_03986 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
LHCGIODF_03987 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHCGIODF_03988 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHCGIODF_03989 9.21e-44 - - - - - - - -
LHCGIODF_03990 1.03e-167 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
LHCGIODF_03991 3.27e-53 yxiC - - S - - - Family of unknown function (DUF5344)
LHCGIODF_03992 5.38e-37 - - - S - - - Domain of unknown function (DUF5082)
LHCGIODF_03993 0.0 - - - L - - - HKD family nuclease
LHCGIODF_03994 1.23e-78 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LHCGIODF_03995 1.47e-136 - - - L - - - COG1112 Superfamily I DNA and RNA helicases and helicase subunits
LHCGIODF_03996 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
LHCGIODF_03997 8.14e-73 yusE - - CO - - - Thioredoxin
LHCGIODF_03998 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
LHCGIODF_03999 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
LHCGIODF_04000 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LHCGIODF_04001 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
LHCGIODF_04002 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LHCGIODF_04003 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
LHCGIODF_04004 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
LHCGIODF_04005 1.11e-13 - - - S - - - YuzL-like protein
LHCGIODF_04006 6.98e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LHCGIODF_04007 4.51e-54 - - - - - - - -
LHCGIODF_04008 8.66e-70 yusN - - M - - - Coat F domain
LHCGIODF_04009 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
LHCGIODF_04010 0.0 yusP - - P - - - Major facilitator superfamily
LHCGIODF_04011 1.7e-84 yusQ - - S - - - Tautomerase enzyme
LHCGIODF_04012 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHCGIODF_04013 8.42e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
LHCGIODF_04014 3.01e-63 yusU - - S - - - Protein of unknown function (DUF2573)
LHCGIODF_04015 2.51e-195 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LHCGIODF_04016 3.48e-88 - - - S - - - YusW-like protein
LHCGIODF_04017 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
LHCGIODF_04018 7.45e-195 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LHCGIODF_04019 6.01e-134 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
LHCGIODF_04021 0.0 - - - D - - - Phage tail tape measure protein
LHCGIODF_04024 1.46e-33 - - - - - - - -
LHCGIODF_04026 8.3e-40 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LHCGIODF_04027 8.17e-38 - - - S - - - Phage head-tail joining protein
LHCGIODF_04029 2.16e-12 - - - - - - - -
LHCGIODF_04030 7.58e-162 - - - S - - - capsid protein
LHCGIODF_04031 1.32e-92 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
LHCGIODF_04032 1.09e-215 - - - S - - - portal protein
LHCGIODF_04034 0.0 terL - - S - - - Terminase
LHCGIODF_04035 1.34e-77 - - - L - - - Terminase, small subunit
LHCGIODF_04038 3.39e-21 - - - - - - - -
LHCGIODF_04039 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
LHCGIODF_04040 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
LHCGIODF_04041 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LHCGIODF_04042 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LHCGIODF_04043 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LHCGIODF_04044 2.88e-106 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LHCGIODF_04045 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
LHCGIODF_04046 4.25e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
LHCGIODF_04047 8.15e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
LHCGIODF_04048 3.06e-158 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
LHCGIODF_04050 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LHCGIODF_04051 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LHCGIODF_04052 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LHCGIODF_04053 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LHCGIODF_04054 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LHCGIODF_04055 2.05e-230 yaaC - - S - - - YaaC-like Protein
LHCGIODF_04056 9.01e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LHCGIODF_04057 4.88e-217 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
LHCGIODF_04058 4.82e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LHCGIODF_04059 5.41e-275 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
LHCGIODF_04061 3.97e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LHCGIODF_04062 2.79e-102 ygaO - - - - - - -
LHCGIODF_04063 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
LHCGIODF_04065 1.11e-146 yhzB - - S - - - B3/4 domain
LHCGIODF_04066 1.2e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LHCGIODF_04067 2.77e-225 yhbB - - S - - - Putative amidase domain
LHCGIODF_04068 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LHCGIODF_04069 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
LHCGIODF_04070 2.66e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LHCGIODF_04071 4.28e-105 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LHCGIODF_04072 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
LHCGIODF_04073 2.22e-142 - - - - - - - -
LHCGIODF_04074 7.33e-230 - - - S - - - Domain of unknown function (DUF2479)
LHCGIODF_04077 2.18e-75 - - - S - - - Bacteriophage holin family
LHCGIODF_04078 1.88e-154 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LHCGIODF_04080 1.66e-22 - - - K - - - Helix-turn-helix domain
LHCGIODF_04083 2.51e-13 - - - - - - - -
LHCGIODF_04084 5.34e-66 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
LHCGIODF_04085 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
LHCGIODF_04086 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LHCGIODF_04087 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
LHCGIODF_04088 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LHCGIODF_04089 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
LHCGIODF_04090 1.23e-185 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LHCGIODF_04091 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
LHCGIODF_04092 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LHCGIODF_04093 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
LHCGIODF_04094 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LHCGIODF_04095 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
LHCGIODF_04096 5.59e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LHCGIODF_04097 0.000654 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
LHCGIODF_04098 3.91e-52 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LHCGIODF_04100 1.57e-121 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LHCGIODF_04102 9.95e-23 - - - - - - - -
LHCGIODF_04103 3.23e-86 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
LHCGIODF_04104 3.12e-98 - - - - - - - -
LHCGIODF_04106 3.46e-10 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LHCGIODF_04107 4.98e-106 yoaW - - - - - - -
LHCGIODF_04108 2.82e-36 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
LHCGIODF_04109 6.23e-131 - - - S - - - Domain of unknown function (DUF3885)
LHCGIODF_04110 3.25e-67 ynaF - - - - - - -
LHCGIODF_04117 8.69e-181 pdaB - - G - - - Polysaccharide deacetylase
LHCGIODF_04118 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
LHCGIODF_04119 1.04e-122 gerD - - - ko:K06294 - ko00000 -
LHCGIODF_04120 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LHCGIODF_04121 1.23e-167 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LHCGIODF_04122 1.47e-90 ybaK - - S - - - Protein of unknown function (DUF2521)
LHCGIODF_04123 1.69e-183 ybaJ - - Q - - - Methyltransferase domain
LHCGIODF_04124 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LHCGIODF_04125 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LHCGIODF_04126 4.33e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LHCGIODF_04127 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHCGIODF_04128 6.34e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHCGIODF_04129 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHCGIODF_04130 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LHCGIODF_04131 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
LHCGIODF_04132 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LHCGIODF_04133 9.89e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
LHCGIODF_04134 3.28e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
LHCGIODF_04135 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
LHCGIODF_04136 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
LHCGIODF_04137 9.28e-230 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LHCGIODF_04138 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
LHCGIODF_04139 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
LHCGIODF_04140 1.63e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LHCGIODF_04141 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
LHCGIODF_04142 8.37e-259 yaaN - - P - - - Belongs to the TelA family
LHCGIODF_04143 2.7e-132 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LHCGIODF_04144 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
LHCGIODF_04145 2.12e-86 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LHCGIODF_04146 8.93e-192 ypuA - - S - - - Secreted protein
LHCGIODF_04147 4.66e-41 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LHCGIODF_04148 8.64e-97 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LHCGIODF_04153 7.27e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
LHCGIODF_04155 7.72e-57 - - - - - - - -
LHCGIODF_04156 1.15e-302 - - - I - - - Pfam Lipase (class 3)
LHCGIODF_04157 8.22e-48 - - - S - - - Protein of unknown function (DUF1433)
LHCGIODF_04159 3.29e-104 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LHCGIODF_04176 6.37e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
LHCGIODF_04177 1.58e-36 - - - - - - - -
LHCGIODF_04178 3.56e-166 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
LHCGIODF_04179 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LHCGIODF_04181 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LHCGIODF_04182 2.11e-66 - - - S - - - Protein of unknown function (DUF1433)
LHCGIODF_04183 3.64e-158 ynaC - - - - - - -
LHCGIODF_04184 8.25e-61 - - - S - - - Restriction endonuclease
LHCGIODF_04185 3.17e-32 - - - - - - - -
LHCGIODF_04186 1.14e-20 - - - S - - - peptidoglycan catabolic process
LHCGIODF_04188 9.06e-82 - - - - - - - -
LHCGIODF_04190 2.3e-41 - - - - - - - -
LHCGIODF_04191 4.35e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LHCGIODF_04192 1.12e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
LHCGIODF_04193 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
LHCGIODF_04194 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LHCGIODF_04195 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LHCGIODF_04197 7.17e-254 - - - S - - - Terminase
LHCGIODF_04198 8.16e-216 - - - S - - - portal protein
LHCGIODF_04199 1.1e-43 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
LHCGIODF_04204 1.86e-99 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LHCGIODF_04210 8.15e-58 - - - S - - - peptidoglycan catabolic process
LHCGIODF_04211 4.01e-33 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
LHCGIODF_04212 2.14e-17 - - - Q - - - methyltransferase
LHCGIODF_04216 1.23e-227 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LHCGIODF_04217 3.68e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
LHCGIODF_04218 3.98e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
LHCGIODF_04219 2.58e-65 - - - - - - - -
LHCGIODF_04220 1.12e-289 - - - KL - - - SNF2 family N-terminal domain
LHCGIODF_04221 3.23e-42 - - - S - - - VRR_NUC
LHCGIODF_04222 6.05e-100 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHCGIODF_04225 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LHCGIODF_04226 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
LHCGIODF_04227 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LHCGIODF_04228 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LHCGIODF_04229 2.77e-37 - - - S ko:K07793 ko02020,map02020 ko00000,ko00001,ko02000 Tripartite tricarboxylate transporter TctA family
LHCGIODF_04239 5.91e-124 - - - T ko:K06919 - ko00000 Phage plasmid primase, P4 family
LHCGIODF_04240 1.3e-102 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)