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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PIEINNCF_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PIEINNCF_00002	1.02e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PIEINNCF_00004	4.07e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
PIEINNCF_00005	9.09e-260	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PIEINNCF_00006	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIEINNCF_00007	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIEINNCF_00008	8.65e-162	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PIEINNCF_00009	5.2e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PIEINNCF_00010	1.36e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PIEINNCF_00011	1.54e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PIEINNCF_00012	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PIEINNCF_00013	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
PIEINNCF_00014	2.7e-227	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
PIEINNCF_00015	8.07e-40	-	-	-	-	-	-	-	-
PIEINNCF_00016	9.81e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PIEINNCF_00019	6.53e-192	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
PIEINNCF_00020	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PIEINNCF_00021	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_00022	9.71e-127	-	-	-	K	-	-	-	transcriptional regulator
PIEINNCF_00023	2.94e-195	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PIEINNCF_00024	2.85e-64	-	-	-	-	-	-	-	-
PIEINNCF_00027	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
PIEINNCF_00028	8.14e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PIEINNCF_00029	8.19e-212	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
PIEINNCF_00030	3.84e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIEINNCF_00032	4.77e-306	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PIEINNCF_00033	2.85e-70	-	-	-	-	-	-	-	-
PIEINNCF_00035	4.4e-55	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIEINNCF_00036	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PIEINNCF_00037	9.4e-143	-	-	-	S	-	-	-	Membrane
PIEINNCF_00038	1.06e-68	-	-	-	-	-	-	-	-
PIEINNCF_00039	3.76e-91	-	-	-	-	-	-	-	-
PIEINNCF_00040	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
PIEINNCF_00041	3.4e-24	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
PIEINNCF_00042	3.13e-23	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
PIEINNCF_00043	3.62e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
PIEINNCF_00044	7.84e-61	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
PIEINNCF_00046	1.42e-39	-	-	-	-	-	-	-	-
PIEINNCF_00047	1.77e-182	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PIEINNCF_00048	4.14e-42	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
PIEINNCF_00049	1.06e-79	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
PIEINNCF_00050	2.22e-162	kdgR	-	-	K	-	-	-	FCD domain
PIEINNCF_00051	2.84e-73	ps105	-	-	-	-	-	-	-
PIEINNCF_00052	5.37e-207	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
PIEINNCF_00053	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PIEINNCF_00054	3.62e-305	-	-	-	EGP	-	-	-	Major Facilitator
PIEINNCF_00055	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
PIEINNCF_00056	7.85e-139	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
PIEINNCF_00058	3.93e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIEINNCF_00059	3.55e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PIEINNCF_00060	2.28e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIEINNCF_00061	1.72e-285	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_00062	0.000666	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PIEINNCF_00064	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
PIEINNCF_00065	3.61e-46	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
PIEINNCF_00066	1.11e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
PIEINNCF_00067	1.23e-149	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
PIEINNCF_00068	1.38e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PIEINNCF_00069	1.01e-292	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PIEINNCF_00070	6.7e-135	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
PIEINNCF_00071	2.11e-175	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
PIEINNCF_00072	1.19e-233	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PIEINNCF_00073	4.18e-262	-	-	-	-	-	-	-	-
PIEINNCF_00074	0.0	-	-	-	EGP	-	-	-	Major Facilitator
PIEINNCF_00075	1.48e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIEINNCF_00077	3.78e-139	-	-	-	-	-	-	-	-
PIEINNCF_00080	2.58e-178	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PIEINNCF_00081	6.02e-216	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PIEINNCF_00082	1.83e-281	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PIEINNCF_00083	7.26e-115	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PIEINNCF_00084	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PIEINNCF_00085	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PIEINNCF_00086	8.47e-240	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PIEINNCF_00087	4.79e-250	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PIEINNCF_00088	8.13e-82	-	-	-	-	-	-	-	-
PIEINNCF_00089	1.35e-97	-	-	-	L	-	-	-	NUDIX domain
PIEINNCF_00090	4.24e-189	-	-	-	EG	-	-	-	EamA-like transporter family
PIEINNCF_00091	3.31e-234	-	-	-	V	-	-	-	ABC transporter transmembrane region
PIEINNCF_00092	3.53e-82	-	-	-	S	-	-	-	Phospholipase A2
PIEINNCF_00094	1.13e-87	-	-	-	K	-	-	-	Tetracyclin repressor, C-terminal all-alpha domain
PIEINNCF_00095	1.01e-73	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
PIEINNCF_00096	1.82e-102	-	-	-	P	-	-	-	ABC-2 family transporter protein
PIEINNCF_00097	3.88e-127	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_00098	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
PIEINNCF_00099	1.35e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PIEINNCF_00100	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PIEINNCF_00101	2.69e-276	-	-	-	-	-	-	-	-
PIEINNCF_00102	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIEINNCF_00103	1.01e-165	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PIEINNCF_00104	5.77e-153	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PIEINNCF_00105	5.32e-117	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
PIEINNCF_00106	2.92e-144	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_00107	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PIEINNCF_00108	6.72e-213	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
PIEINNCF_00109	9.64e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PIEINNCF_00110	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
PIEINNCF_00111	4.34e-75	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
PIEINNCF_00112	0.0	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
PIEINNCF_00113	2.43e-206	lysR5	-	-	K	-	-	-	LysR substrate binding domain
PIEINNCF_00114	3.87e-262	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIEINNCF_00115	1.91e-46	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
PIEINNCF_00116	2.26e-215	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PIEINNCF_00117	3.78e-170	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PIEINNCF_00118	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
PIEINNCF_00119	1.45e-172	-	-	-	-	-	-	-	-
PIEINNCF_00120	4e-133	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
PIEINNCF_00121	0.0	-	-	-	-	-	-	-	-
PIEINNCF_00122	1.04e-47	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
PIEINNCF_00123	1.16e-116	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
PIEINNCF_00124	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
PIEINNCF_00126	4.68e-53	-	-	-	-	-	-	-	-
PIEINNCF_00127	2.66e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
PIEINNCF_00128	2e-238	yveB	-	-	I	-	-	-	PAP2 superfamily
PIEINNCF_00129	2.35e-269	mccF	-	-	V	-	-	-	LD-carboxypeptidase
PIEINNCF_00130	6.55e-57	-	-	-	-	-	-	-	-
PIEINNCF_00131	2.61e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PIEINNCF_00132	2.47e-117	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
PIEINNCF_00133	1.17e-245	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIEINNCF_00134	1.21e-59	-	-	-	-	-	-	-	-
PIEINNCF_00135	2.74e-112	-	-	-	K	-	-	-	Transcriptional regulator
PIEINNCF_00136	1.07e-239	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	alcohol dehydrogenase
PIEINNCF_00137	1.61e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
PIEINNCF_00138	2.42e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
PIEINNCF_00139	0.0	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PIEINNCF_00140	1.2e-61	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
PIEINNCF_00141	1.44e-228	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIEINNCF_00142	6.64e-39	-	-	-	-	-	-	-	-
PIEINNCF_00143	1.04e-134	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PIEINNCF_00144	0.0	-	-	-	-	-	-	-	-
PIEINNCF_00146	4.04e-167	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PIEINNCF_00147	2.38e-170	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PIEINNCF_00148	1.99e-241	ynjC	-	-	S	-	-	-	Cell surface protein
PIEINNCF_00150	0.0	-	-	-	L	-	-	-	Mga helix-turn-helix domain
PIEINNCF_00151	5.89e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
PIEINNCF_00152	1.1e-76	-	-	-	-	-	-	-	-
PIEINNCF_00153	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PIEINNCF_00154	1.07e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIEINNCF_00155	6.72e-204	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
PIEINNCF_00156	1.06e-175	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
PIEINNCF_00157	8.86e-62	-	-	-	S	-	-	-	Thiamine-binding protein
PIEINNCF_00158	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
PIEINNCF_00159	4.77e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIEINNCF_00160	9.33e-178	bmr3	-	-	EGP	-	-	-	Major Facilitator
PIEINNCF_00161	4.07e-118	bmr3	-	-	EGP	-	-	-	Major Facilitator
PIEINNCF_00163	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PIEINNCF_00164	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PIEINNCF_00165	6.7e-130	-	-	-	-	-	-	-	-
PIEINNCF_00166	1.28e-18	-	-	-	-	-	-	-	-
PIEINNCF_00167	4.8e-62	-	-	-	-	-	-	-	-
PIEINNCF_00168	9.11e-88	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PIEINNCF_00169	7.76e-56	-	-	-	-	-	-	-	-
PIEINNCF_00170	4.15e-103	-	-	-	S	-	-	-	NUDIX domain
PIEINNCF_00171	2.21e-275	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
PIEINNCF_00172	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
PIEINNCF_00173	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
PIEINNCF_00174	6.18e-150	-	-	-	-	-	-	-	-
PIEINNCF_00175	1.21e-286	-	-	-	S	ko:K06872	-	ko00000	TPM domain
PIEINNCF_00176	3.56e-177	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
PIEINNCF_00177	6.45e-74	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
PIEINNCF_00178	1.47e-07	-	-	-	-	-	-	-	-
PIEINNCF_00179	5.12e-117	-	-	-	-	-	-	-	-
PIEINNCF_00180	4.85e-65	-	-	-	-	-	-	-	-
PIEINNCF_00181	1.63e-109	-	-	-	C	-	-	-	Flavodoxin
PIEINNCF_00182	5.54e-50	-	-	-	-	-	-	-	-
PIEINNCF_00183	2.82e-36	-	-	-	-	-	-	-	-
PIEINNCF_00184	2.86e-219	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIEINNCF_00185	1.31e-93	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
PIEINNCF_00186	4.95e-53	-	-	-	S	-	-	-	Transglycosylase associated protein
PIEINNCF_00187	2.35e-112	-	-	-	S	-	-	-	Protein conserved in bacteria
PIEINNCF_00188	4.15e-34	-	-	-	-	-	-	-	-
PIEINNCF_00189	8.12e-90	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PIEINNCF_00190	1.97e-92	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PIEINNCF_00191	2.66e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
PIEINNCF_00192	1.42e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
PIEINNCF_00193	6.93e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PIEINNCF_00194	3.56e-138	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
PIEINNCF_00195	1.11e-163	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
PIEINNCF_00196	4.01e-87	-	-	-	-	-	-	-	-
PIEINNCF_00197	1.94e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
PIEINNCF_00198	2.29e-187	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PIEINNCF_00199	1.49e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
PIEINNCF_00200	1.11e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PIEINNCF_00201	3.26e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
PIEINNCF_00202	8.02e-236	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PIEINNCF_00203	2.04e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
PIEINNCF_00204	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PIEINNCF_00205	6.85e-155	-	-	-	-	-	-	-	-
PIEINNCF_00206	1.68e-156	vanR	-	-	K	-	-	-	response regulator
PIEINNCF_00207	2.81e-278	hpk31	-	-	T	-	-	-	Histidine kinase
PIEINNCF_00208	9.18e-302	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PIEINNCF_00209	1.02e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PIEINNCF_00210	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PIEINNCF_00211	2.71e-182	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PIEINNCF_00212	8.2e-211	yvgN	-	-	C	-	-	-	Aldo keto reductase
PIEINNCF_00213	8.55e-185	gntR	-	-	K	-	-	-	rpiR family
PIEINNCF_00214	2.98e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
PIEINNCF_00215	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PIEINNCF_00216	6.55e-270	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
PIEINNCF_00217	3.74e-75	-	-	-	-	-	-	-	-
PIEINNCF_00218	5.86e-167	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PIEINNCF_00219	8.13e-171	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
PIEINNCF_00220	2.09e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
PIEINNCF_00221	2.6e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
PIEINNCF_00222	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
PIEINNCF_00223	5.92e-241	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PIEINNCF_00224	1.27e-315	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PIEINNCF_00225	3.46e-103	-	-	-	T	-	-	-	Sh3 type 3 domain protein
PIEINNCF_00226	1.05e-171	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
PIEINNCF_00227	3.84e-187	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PIEINNCF_00228	2.1e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
PIEINNCF_00229	4.42e-54	-	-	-	-	-	-	-	-
PIEINNCF_00230	1.26e-139	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PIEINNCF_00231	1.01e-224	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
PIEINNCF_00232	0.0	-	-	-	S	-	-	-	ABC transporter
PIEINNCF_00233	2.8e-173	ypaC	-	-	Q	-	-	-	Methyltransferase domain
PIEINNCF_00234	1.45e-46	-	-	-	-	-	-	-	-
PIEINNCF_00235	5.19e-90	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
PIEINNCF_00237	3.02e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PIEINNCF_00238	2.2e-176	-	-	-	S	-	-	-	Putative threonine/serine exporter
PIEINNCF_00239	2.51e-98	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PIEINNCF_00241	2.29e-273	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
PIEINNCF_00242	1.04e-191	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
PIEINNCF_00243	1.1e-182	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
PIEINNCF_00244	1.23e-179	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
PIEINNCF_00245	1.65e-159	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIEINNCF_00246	7.59e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PIEINNCF_00247	1.31e-302	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEINNCF_00248	4.1e-152	-	-	-	G	-	-	-	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PIEINNCF_00249	4.12e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PIEINNCF_00250	3.24e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PIEINNCF_00251	7.71e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
PIEINNCF_00252	5.19e-197	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
PIEINNCF_00255	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
PIEINNCF_00256	3.74e-205	-	-	-	-	-	-	-	-
PIEINNCF_00257	4.13e-156	-	-	-	-	-	-	-	-
PIEINNCF_00258	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
PIEINNCF_00259	2.87e-306	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIEINNCF_00260	9.04e-110	-	-	-	-	-	-	-	-
PIEINNCF_00261	0.0	strH	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Gram-positive signal peptide protein, YSIRK family
PIEINNCF_00262	9.12e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PIEINNCF_00263	5.43e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
PIEINNCF_00264	1.63e-280	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
PIEINNCF_00265	2.26e-288	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PIEINNCF_00266	0.0	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
PIEINNCF_00267	5.61e-108	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PIEINNCF_00268	4.68e-206	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PIEINNCF_00269	3.66e-187	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PIEINNCF_00270	2.72e-85	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PIEINNCF_00271	4.39e-286	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
PIEINNCF_00272	9.16e-244	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PIEINNCF_00273	4.46e-251	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PIEINNCF_00274	0.0	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEINNCF_00275	2.96e-78	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PIEINNCF_00276	2.04e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
PIEINNCF_00277	2.01e-240	-	-	-	E	-	-	-	M42 glutamyl aminopeptidase
PIEINNCF_00278	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PIEINNCF_00279	2.45e-309	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PIEINNCF_00280	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PIEINNCF_00281	3.98e-143	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
PIEINNCF_00283	1.78e-120	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
PIEINNCF_00284	1.22e-307	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PIEINNCF_00285	4.64e-143	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
PIEINNCF_00286	1.63e-164	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PIEINNCF_00287	4.9e-105	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
PIEINNCF_00288	1.44e-192	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PIEINNCF_00289	6.07e-138	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PIEINNCF_00290	7.39e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PIEINNCF_00291	0.0	-	-	-	E	-	-	-	Amino acid permease
PIEINNCF_00292	1.16e-45	-	-	-	-	-	-	-	-
PIEINNCF_00293	2.08e-240	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
PIEINNCF_00294	2.2e-86	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PIEINNCF_00295	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PIEINNCF_00296	4.84e-198	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PIEINNCF_00297	1.41e-214	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
PIEINNCF_00298	1.1e-206	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PIEINNCF_00299	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
PIEINNCF_00300	2.71e-83	-	-	-	K	-	-	-	Transcriptional regulator
PIEINNCF_00301	3.63e-260	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PIEINNCF_00302	1.93e-138	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_00303	2.23e-138	-	-	-	C	-	-	-	NADPH quinone reductase
PIEINNCF_00304	3.44e-300	-	-	-	EGP	-	-	-	Major Facilitator
PIEINNCF_00305	3.79e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PIEINNCF_00306	2.14e-131	-	-	-	-	-	-	-	-
PIEINNCF_00307	4.22e-41	-	-	-	-	-	-	-	-
PIEINNCF_00308	3.9e-83	-	-	-	-	-	-	-	-
PIEINNCF_00309	2.01e-80	-	-	-	-	-	-	-	-
PIEINNCF_00310	0.0	frdC	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
PIEINNCF_00311	1.64e-250	-	-	-	GKT	-	-	-	transcriptional antiterminator
PIEINNCF_00312	3.38e-66	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PIEINNCF_00313	5.62e-292	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PIEINNCF_00314	1.39e-87	-	-	-	-	-	-	-	-
PIEINNCF_00315	6.47e-208	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
PIEINNCF_00316	2.61e-148	-	-	-	S	-	-	-	Zeta toxin
PIEINNCF_00317	7.53e-202	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
PIEINNCF_00318	9.64e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
PIEINNCF_00319	9.71e-228	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
PIEINNCF_00320	6.41e-190	-	3.1.1.24	-	S	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
PIEINNCF_00322	6.87e-293	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
PIEINNCF_00323	2.37e-91	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
PIEINNCF_00324	5.11e-93	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
PIEINNCF_00325	1.13e-192	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
PIEINNCF_00326	2.7e-162	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
PIEINNCF_00327	4.65e-128	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
PIEINNCF_00328	3.4e-36	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PIEINNCF_00329	1.62e-227	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
PIEINNCF_00330	9.79e-51	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PIEINNCF_00331	4.9e-51	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
PIEINNCF_00332	3.24e-97	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PIEINNCF_00333	7.56e-77	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PIEINNCF_00334	0.0	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
PIEINNCF_00335	3.8e-141	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
PIEINNCF_00336	1.69e-194	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PIEINNCF_00337	9.88e-276	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
PIEINNCF_00338	1.69e-256	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PIEINNCF_00339	7.14e-46	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
PIEINNCF_00341	1.69e-12	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	K02749 PTS system, arbutin-like IIB component K02750
PIEINNCF_00342	2.26e-60	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PIEINNCF_00343	9.56e-63	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PIEINNCF_00344	5.27e-207	-	-	-	P	-	-	-	YhfZ C-terminal domain
PIEINNCF_00346	1.96e-73	-	-	-	S	-	-	-	Protein of unknown function DUF2620
PIEINNCF_00347	1.66e-274	-	-	-	S	-	-	-	Protein of unknown function
PIEINNCF_00348	4.14e-199	php	-	-	S	ko:K07048	-	ko00000	Phosphotriesterase family
PIEINNCF_00349	5.99e-233	-	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
PIEINNCF_00350	2.2e-256	-	-	-	E	-	-	-	Alanine racemase, N-terminal domain
PIEINNCF_00351	1.89e-294	-	-	-	G	-	-	-	Metalloenzyme superfamily
PIEINNCF_00352	0.0	ebgA	3.2.1.23	-	G	ko:K01190,ko:K12111	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
PIEINNCF_00353	3.09e-53	-	-	-	E	-	-	-	Amino Acid
PIEINNCF_00354	4.48e-273	-	-	-	E	-	-	-	Amino Acid
PIEINNCF_00355	7.22e-97	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
PIEINNCF_00356	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_00357	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_00358	3.53e-144	-	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
PIEINNCF_00359	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_00360	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_00362	5.12e-112	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIEINNCF_00363	1.63e-237	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PIEINNCF_00364	5.82e-153	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_00365	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
PIEINNCF_00366	6.17e-193	-	-	-	S	-	-	-	hydrolase
PIEINNCF_00368	1.49e-58	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
PIEINNCF_00369	1.15e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
PIEINNCF_00370	1.48e-109	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PIEINNCF_00371	2.18e-177	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PIEINNCF_00372	1.59e-195	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PIEINNCF_00373	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
PIEINNCF_00374	5.07e-89	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PIEINNCF_00375	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PIEINNCF_00376	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PIEINNCF_00377	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PIEINNCF_00379	9.66e-108	pip	-	-	V	ko:K01421	-	ko00000	domain protein
PIEINNCF_00380	7.25e-140	pip	-	-	V	ko:K01421	-	ko00000	domain protein
PIEINNCF_00381	7.59e-131	pip	-	-	V	ko:K01421	-	ko00000	domain protein
PIEINNCF_00382	0.0	-	-	-	GK	-	-	-	helix_turn_helix, arabinose operon control protein
PIEINNCF_00383	9.2e-242	-	-	-	G	-	-	-	Major Facilitator Superfamily
PIEINNCF_00385	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_00386	5.05e-58	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_00387	2.9e-280	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
PIEINNCF_00388	3.17e-200	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PIEINNCF_00389	1.67e-252	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
PIEINNCF_00390	4.99e-105	-	-	-	-	-	-	-	-
PIEINNCF_00391	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PIEINNCF_00392	2.95e-22	-	-	-	-	-	-	-	-
PIEINNCF_00393	2.03e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIEINNCF_00394	2.98e-78	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
PIEINNCF_00395	1.17e-132	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
PIEINNCF_00396	1.03e-242	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
PIEINNCF_00397	1.01e-99	-	-	-	O	-	-	-	OsmC-like protein
PIEINNCF_00398	0.0	-	-	-	L	-	-	-	Exonuclease
PIEINNCF_00399	4.23e-64	yczG	-	-	K	-	-	-	Helix-turn-helix domain
PIEINNCF_00400	7.1e-256	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
PIEINNCF_00401	8.11e-138	ydfF	-	-	K	-	-	-	Transcriptional
PIEINNCF_00402	7.64e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PIEINNCF_00403	5.36e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
PIEINNCF_00404	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PIEINNCF_00405	5.8e-248	pbpE	-	-	V	-	-	-	Beta-lactamase
PIEINNCF_00406	3.81e-191	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
PIEINNCF_00407	2.61e-184	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
PIEINNCF_00408	3.29e-183	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PIEINNCF_00409	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase, catalytic domain
PIEINNCF_00410	7.19e-284	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
PIEINNCF_00411	0.0	-	-	-	E	-	-	-	Amino acid permease
PIEINNCF_00412	9.74e-98	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PIEINNCF_00413	2.64e-208	-	-	-	S	-	-	-	reductase
PIEINNCF_00414	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
PIEINNCF_00415	7.58e-134	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
PIEINNCF_00416	0.0	yvcC	-	-	M	-	-	-	Cna protein B-type domain
PIEINNCF_00417	3.37e-161	-	-	-	M	-	-	-	domain protein
PIEINNCF_00418	1.19e-234	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
PIEINNCF_00419	3.16e-258	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
PIEINNCF_00420	4.78e-164	XK27_12140	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PIEINNCF_00421	2.57e-66	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PIEINNCF_00422	1.5e-133	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PIEINNCF_00423	1.36e-134	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PIEINNCF_00424	1.82e-162	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
PIEINNCF_00425	8.47e-252	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PIEINNCF_00426	3.4e-65	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
PIEINNCF_00427	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_00428	2.23e-111	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_00429	1.26e-60	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_00430	1.32e-102	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
PIEINNCF_00431	6.7e-246	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
PIEINNCF_00432	3.98e-118	-	-	-	-	-	-	-	-
PIEINNCF_00433	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PIEINNCF_00434	1.07e-204	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PIEINNCF_00435	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PIEINNCF_00436	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
PIEINNCF_00437	0.0	ycaM	-	-	E	-	-	-	amino acid
PIEINNCF_00438	1.66e-117	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
PIEINNCF_00439	2.07e-205	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
PIEINNCF_00440	2.21e-204	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
PIEINNCF_00441	7.63e-167	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PIEINNCF_00442	1.25e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PIEINNCF_00443	6.33e-275	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PIEINNCF_00444	2.1e-215	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PIEINNCF_00445	1.96e-122	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
PIEINNCF_00446	1.26e-60	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_00447	2.23e-111	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_00448	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_00452	5.8e-10	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PIEINNCF_00453	1.62e-76	-	-	-	-	-	-	-	-
PIEINNCF_00454	3.01e-96	dpnM	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
PIEINNCF_00456	1.43e-270	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PIEINNCF_00457	3.96e-185	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
PIEINNCF_00458	5.79e-157	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIEINNCF_00459	6.88e-45	-	-	-	-	-	-	-	-
PIEINNCF_00460	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PIEINNCF_00461	6.36e-141	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PIEINNCF_00462	9.99e-225	-	-	-	S	-	-	-	Cell surface protein
PIEINNCF_00463	1.78e-58	-	-	-	-	-	-	-	-
PIEINNCF_00464	9.4e-250	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
PIEINNCF_00465	3.92e-153	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PIEINNCF_00466	2.21e-74	-	-	-	-	-	-	-	-
PIEINNCF_00467	3.82e-142	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
PIEINNCF_00468	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
PIEINNCF_00469	1.15e-223	yicL	-	-	EG	-	-	-	EamA-like transporter family
PIEINNCF_00470	0.0	-	-	-	-	-	-	-	-
PIEINNCF_00471	1.23e-185	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PIEINNCF_00472	4.07e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
PIEINNCF_00473	5.02e-190	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
PIEINNCF_00474	1.86e-209	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
PIEINNCF_00475	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PIEINNCF_00476	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_00477	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIEINNCF_00478	3.34e-286	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
PIEINNCF_00479	5.43e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
PIEINNCF_00480	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PIEINNCF_00481	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIEINNCF_00482	1.02e-281	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PIEINNCF_00483	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
PIEINNCF_00484	1.13e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
PIEINNCF_00485	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
PIEINNCF_00486	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
PIEINNCF_00487	2.1e-89	-	-	-	-	-	-	-	-
PIEINNCF_00488	1.37e-99	-	-	-	O	-	-	-	OsmC-like protein
PIEINNCF_00489	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
PIEINNCF_00490	6.43e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
PIEINNCF_00491	3.05e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
PIEINNCF_00492	9.94e-316	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PIEINNCF_00493	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
PIEINNCF_00494	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PIEINNCF_00495	5.49e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PIEINNCF_00496	2.42e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
PIEINNCF_00497	3.63e-133	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
PIEINNCF_00498	6.89e-107	-	-	-	L	-	-	-	Transposase DDE domain
PIEINNCF_00499	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PIEINNCF_00500	4.94e-44	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
PIEINNCF_00501	6.45e-209	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIEINNCF_00502	2.06e-186	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PIEINNCF_00503	3.16e-158	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
PIEINNCF_00504	1.06e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
PIEINNCF_00505	3.4e-202	-	-	-	C	-	-	-	nadph quinone reductase
PIEINNCF_00506	3.8e-316	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
PIEINNCF_00507	3.97e-227	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
PIEINNCF_00508	1.23e-153	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
PIEINNCF_00509	8.33e-156	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
PIEINNCF_00511	3.55e-168	-	-	-	L	ko:K07487	-	ko00000	COG3666 Transposase and inactivated derivatives
PIEINNCF_00514	3.21e-05	-	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Psort location CytoplasmicMembrane, score
PIEINNCF_00515	1.62e-159	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	proteolysis
PIEINNCF_00516	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
PIEINNCF_00517	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
PIEINNCF_00518	1.8e-145	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
PIEINNCF_00519	5.46e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PIEINNCF_00520	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
PIEINNCF_00521	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PIEINNCF_00522	2.75e-177	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PIEINNCF_00523	9.48e-204	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
PIEINNCF_00524	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
PIEINNCF_00525	2.48e-201	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIEINNCF_00526	2.69e-140	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIEINNCF_00527	3.1e-66	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
PIEINNCF_00528	2.83e-283	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PIEINNCF_00529	4.24e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PIEINNCF_00530	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PIEINNCF_00531	1.02e-219	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PIEINNCF_00532	1.18e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PIEINNCF_00535	6.77e-111	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PIEINNCF_00536	2.68e-67	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PIEINNCF_00537	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PIEINNCF_00538	9.83e-37	-	-	-	-	-	-	-	-
PIEINNCF_00539	4.48e-160	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
PIEINNCF_00540	1.75e-225	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
PIEINNCF_00541	1.91e-235	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
PIEINNCF_00542	1.07e-120	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
PIEINNCF_00543	1.25e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
PIEINNCF_00544	4.13e-181	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
PIEINNCF_00545	5.3e-150	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
PIEINNCF_00546	3.23e-270	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PIEINNCF_00547	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
PIEINNCF_00548	6.8e-21	-	-	-	-	-	-	-	-
PIEINNCF_00549	7.42e-112	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PIEINNCF_00551	3.37e-271	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
PIEINNCF_00552	1.84e-190	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PIEINNCF_00553	1.06e-156	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
PIEINNCF_00555	2.6e-113	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PIEINNCF_00556	7.83e-153	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PIEINNCF_00557	9.5e-199	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PIEINNCF_00558	2.26e-250	-	-	-	-	-	-	-	-
PIEINNCF_00560	3.99e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
PIEINNCF_00561	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
PIEINNCF_00562	2.62e-214	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
PIEINNCF_00563	1.19e-212	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
PIEINNCF_00564	3.78e-205	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PIEINNCF_00565	1.95e-179	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_00566	2.37e-222	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
PIEINNCF_00567	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
PIEINNCF_00568	8.07e-233	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
PIEINNCF_00569	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
PIEINNCF_00570	3.08e-93	-	-	-	S	-	-	-	GtrA-like protein
PIEINNCF_00571	3.91e-159	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
PIEINNCF_00572	3.5e-308	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
PIEINNCF_00573	2.42e-88	-	-	-	S	-	-	-	Belongs to the HesB IscA family
PIEINNCF_00574	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
PIEINNCF_00575	6.21e-206	-	-	-	S	-	-	-	KR domain
PIEINNCF_00576	1.35e-202	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
PIEINNCF_00577	6.91e-156	ydgI	-	-	C	-	-	-	Nitroreductase family
PIEINNCF_00578	1.3e-262	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
PIEINNCF_00579	6.65e-137	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIEINNCF_00581	9.62e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
PIEINNCF_00583	5.89e-42	-	-	-	-	-	-	-	-
PIEINNCF_00584	1.62e-19	-	-	-	-	-	-	-	-
PIEINNCF_00586	5.47e-33	-	-	-	-	-	-	-	-
PIEINNCF_00587	4.71e-200	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
PIEINNCF_00588	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
PIEINNCF_00589	3.28e-95	-	-	-	-	-	-	-	-
PIEINNCF_00590	3.25e-70	-	-	-	S	-	-	-	Phage head-tail joining protein
PIEINNCF_00592	2.12e-27	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	COG1403 Restriction endonuclease
PIEINNCF_00593	5.66e-106	terS	-	-	L	-	-	-	Phage terminase, small subunit
PIEINNCF_00594	1.58e-63	-	-	-	S	-	-	-	overlaps another CDS with the same product name
PIEINNCF_00595	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_00596	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_00597	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
PIEINNCF_00598	3e-29	-	-	-	-	-	-	-	-
PIEINNCF_00599	4.19e-283	-	-	-	S	-	-	-	Phage portal protein
PIEINNCF_00600	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
PIEINNCF_00601	9.63e-61	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PIEINNCF_00605	7.56e-242	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
PIEINNCF_00606	1.17e-77	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
PIEINNCF_00607	2.7e-62	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
PIEINNCF_00608	4.91e-55	-	-	-	-	-	-	-	-
PIEINNCF_00609	2.02e-245	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PIEINNCF_00611	1.32e-71	-	-	-	-	-	-	-	-
PIEINNCF_00612	7.27e-104	-	-	-	-	-	-	-	-
PIEINNCF_00613	5.77e-267	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
PIEINNCF_00614	1.58e-33	-	-	-	-	-	-	-	-
PIEINNCF_00615	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PIEINNCF_00616	8.86e-60	-	-	-	-	-	-	-	-
PIEINNCF_00617	8.47e-214	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
PIEINNCF_00618	4.84e-115	-	-	-	S	-	-	-	Flavin reductase like domain
PIEINNCF_00619	1.94e-90	-	-	-	-	-	-	-	-
PIEINNCF_00620	6.56e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PIEINNCF_00621	1.7e-81	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
PIEINNCF_00622	2.2e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PIEINNCF_00623	2.41e-201	mleR	-	-	K	-	-	-	LysR family
PIEINNCF_00624	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
PIEINNCF_00625	1.46e-216	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
PIEINNCF_00626	8.23e-117	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PIEINNCF_00627	4.6e-113	-	-	-	C	-	-	-	FMN binding
PIEINNCF_00628	2.19e-222	-	-	-	K	ko:K20373,ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
PIEINNCF_00629	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PIEINNCF_00630	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
PIEINNCF_00631	3.86e-78	-	-	-	-	-	-	-	-
PIEINNCF_00632	4.45e-169	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PIEINNCF_00633	1.36e-105	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
PIEINNCF_00634	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
PIEINNCF_00635	1.56e-230	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	carboxylic ester hydrolase activity
PIEINNCF_00636	4.86e-58	-	-	-	-	-	-	-	-
PIEINNCF_00637	4.89e-122	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PIEINNCF_00638	1.14e-255	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PIEINNCF_00639	7.46e-157	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
PIEINNCF_00640	2.24e-101	-	-	-	K	-	-	-	Transcriptional regulator
PIEINNCF_00641	3.41e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PIEINNCF_00642	3.83e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
PIEINNCF_00643	3.58e-199	dkgB	-	-	S	-	-	-	reductase
PIEINNCF_00644	5.55e-200	-	-	-	-	-	-	-	-
PIEINNCF_00645	1.02e-197	-	-	-	S	-	-	-	Alpha beta hydrolase
PIEINNCF_00646	1.69e-33	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
PIEINNCF_00647	2.79e-107	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
PIEINNCF_00648	4.49e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
PIEINNCF_00649	1.2e-283	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PIEINNCF_00650	1.69e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PIEINNCF_00651	1.3e-136	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
PIEINNCF_00652	2.95e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PIEINNCF_00653	4.54e-241	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PIEINNCF_00654	2.62e-263	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PIEINNCF_00655	3.46e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PIEINNCF_00656	4.49e-88	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PIEINNCF_00657	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PIEINNCF_00658	4.86e-149	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
PIEINNCF_00659	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PIEINNCF_00660	1.46e-263	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PIEINNCF_00661	1.13e-307	ytoI	-	-	K	-	-	-	DRTGG domain
PIEINNCF_00662	3.03e-229	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
PIEINNCF_00663	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PIEINNCF_00664	4.26e-221	-	-	-	-	-	-	-	-
PIEINNCF_00665	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PIEINNCF_00667	4.89e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
PIEINNCF_00668	2.67e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PIEINNCF_00669	1.3e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
PIEINNCF_00670	1.65e-47	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PIEINNCF_00671	3.4e-120	cvpA	-	-	S	-	-	-	Colicin V production protein
PIEINNCF_00672	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PIEINNCF_00673	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PIEINNCF_00674	1.04e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
PIEINNCF_00675	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIEINNCF_00676	9.86e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
PIEINNCF_00677	6.97e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIEINNCF_00678	1.18e-311	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PIEINNCF_00679	1.66e-111	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
PIEINNCF_00680	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PIEINNCF_00681	1.64e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
PIEINNCF_00682	1.9e-175	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
PIEINNCF_00683	9.32e-112	ykuL	-	-	S	-	-	-	CBS domain
PIEINNCF_00684	6.86e-201	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
PIEINNCF_00685	6.86e-198	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
PIEINNCF_00686	1.49e-46	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PIEINNCF_00687	9.5e-112	ytxH	-	-	S	-	-	-	YtxH-like protein
PIEINNCF_00688	7.49e-117	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
PIEINNCF_00689	2.2e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PIEINNCF_00690	3.03e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
PIEINNCF_00691	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
PIEINNCF_00692	1.45e-161	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
PIEINNCF_00693	5.87e-177	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PIEINNCF_00694	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
PIEINNCF_00695	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
PIEINNCF_00696	9.98e-73	-	-	-	-	-	-	-	-
PIEINNCF_00697	8.45e-241	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
PIEINNCF_00698	3.27e-151	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
PIEINNCF_00699	2.48e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PIEINNCF_00700	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PIEINNCF_00701	2.06e-150	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
PIEINNCF_00702	1.34e-186	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PIEINNCF_00703	6.43e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
PIEINNCF_00704	7.15e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
PIEINNCF_00705	2.26e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
PIEINNCF_00706	1.35e-237	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
PIEINNCF_00707	2.99e-140	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PIEINNCF_00708	1.17e-82	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
PIEINNCF_00709	1.45e-46	-	-	-	-	-	-	-	-
PIEINNCF_00710	5.19e-90	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
PIEINNCF_00737	1.68e-122	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
PIEINNCF_00738	0.0	ybeC	-	-	E	-	-	-	amino acid
PIEINNCF_00739	1.09e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PIEINNCF_00740	1.13e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PIEINNCF_00741	1.58e-220	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PIEINNCF_00743	2.59e-276	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PIEINNCF_00744	1.52e-57	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
PIEINNCF_00745	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PIEINNCF_00746	8.92e-105	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
PIEINNCF_00747	1.45e-46	-	-	-	-	-	-	-	-
PIEINNCF_00748	5.19e-90	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
PIEINNCF_00753	6.91e-92	-	-	-	-	-	-	-	-
PIEINNCF_00754	7.89e-268	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PIEINNCF_00755	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
PIEINNCF_00756	6.89e-107	-	-	-	K	-	-	-	MerR HTH family regulatory protein
PIEINNCF_00757	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PIEINNCF_00758	4.87e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PIEINNCF_00759	1.05e-154	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
PIEINNCF_00760	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PIEINNCF_00761	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PIEINNCF_00762	9.39e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PIEINNCF_00763	6.89e-107	-	-	-	L	-	-	-	Transposase DDE domain
PIEINNCF_00764	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PIEINNCF_00765	6.44e-45	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
PIEINNCF_00766	7.92e-182	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PIEINNCF_00767	2.55e-121	-	-	-	F	-	-	-	NUDIX domain
PIEINNCF_00769	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PIEINNCF_00770	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PIEINNCF_00771	5.66e-111	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
PIEINNCF_00774	1.23e-295	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PIEINNCF_00775	0.0	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PIEINNCF_00776	5.05e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
PIEINNCF_00777	4.58e-311	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
PIEINNCF_00778	1.71e-161	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PIEINNCF_00779	6.72e-91	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PIEINNCF_00780	6.41e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
PIEINNCF_00781	1.79e-138	-	-	-	S	-	-	-	CYTH
PIEINNCF_00782	1.19e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
PIEINNCF_00783	1.05e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PIEINNCF_00784	2.88e-218	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PIEINNCF_00785	4.86e-259	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PIEINNCF_00786	1.76e-145	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
PIEINNCF_00787	1.09e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PIEINNCF_00788	9.35e-254	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
PIEINNCF_00789	2e-82	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
PIEINNCF_00790	4.12e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIEINNCF_00791	4.94e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PIEINNCF_00792	1.94e-219	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PIEINNCF_00793	3.44e-200	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
PIEINNCF_00794	1.31e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PIEINNCF_00795	4.04e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
PIEINNCF_00796	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PIEINNCF_00797	5.21e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
PIEINNCF_00798	4.6e-308	ymfH	-	-	S	-	-	-	Peptidase M16
PIEINNCF_00799	3.01e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PIEINNCF_00800	1.15e-169	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
PIEINNCF_00801	9.93e-136	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PIEINNCF_00802	7.09e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
PIEINNCF_00803	1.03e-240	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PIEINNCF_00804	7.95e-317	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
PIEINNCF_00805	2.93e-151	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
PIEINNCF_00806	1.84e-298	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
PIEINNCF_00807	4.32e-104	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
PIEINNCF_00808	3.24e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PIEINNCF_00809	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PIEINNCF_00810	8.69e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PIEINNCF_00811	1.28e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
PIEINNCF_00813	5.24e-257	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
PIEINNCF_00814	1.83e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PIEINNCF_00815	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PIEINNCF_00816	1.76e-196	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PIEINNCF_00817	4.48e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PIEINNCF_00818	1.06e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
PIEINNCF_00819	2.6e-191	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIEINNCF_00820	3.54e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIEINNCF_00821	3.82e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
PIEINNCF_00822	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
PIEINNCF_00823	5.23e-50	-	-	-	-	-	-	-	-
PIEINNCF_00824	3.07e-50	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
PIEINNCF_00825	8.27e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PIEINNCF_00826	9.99e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PIEINNCF_00827	6.29e-250	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
PIEINNCF_00828	1.43e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PIEINNCF_00829	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PIEINNCF_00830	1.83e-147	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
PIEINNCF_00831	1.92e-214	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
PIEINNCF_00832	2.43e-117	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PIEINNCF_00833	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PIEINNCF_00834	1.99e-153	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
PIEINNCF_00835	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PIEINNCF_00836	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PIEINNCF_00837	1.21e-109	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PIEINNCF_00838	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PIEINNCF_00839	2.99e-248	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
PIEINNCF_00840	9.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PIEINNCF_00841	7.84e-106	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
PIEINNCF_00842	5.97e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PIEINNCF_00844	3.11e-29	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
PIEINNCF_00845	9.48e-229	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
PIEINNCF_00846	2.1e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PIEINNCF_00847	2.16e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
PIEINNCF_00848	2.81e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PIEINNCF_00849	8.35e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PIEINNCF_00850	4.28e-292	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
PIEINNCF_00851	1.33e-63	-	-	-	-	-	-	-	-
PIEINNCF_00852	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PIEINNCF_00853	5.04e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PIEINNCF_00854	9.45e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
PIEINNCF_00855	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PIEINNCF_00856	4.47e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PIEINNCF_00857	1.92e-301	-	-	-	L	ko:K07485	-	ko00000	Transposase
PIEINNCF_00858	6.33e-226	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
PIEINNCF_00859	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
PIEINNCF_00860	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PIEINNCF_00861	3.58e-146	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PIEINNCF_00862	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PIEINNCF_00863	5.13e-21	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIEINNCF_00864	2.33e-23	-	-	-	-	-	-	-	-
PIEINNCF_00865	1.33e-31	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
PIEINNCF_00866	1.25e-306	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
PIEINNCF_00867	2.48e-311	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIEINNCF_00868	1.1e-188	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIEINNCF_00869	7.01e-213	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
PIEINNCF_00870	1e-189	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
PIEINNCF_00871	5.37e-40	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
PIEINNCF_00872	8.55e-135	-	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
PIEINNCF_00873	7.28e-117	-	-	-	-	-	-	-	-
PIEINNCF_00874	4e-203	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PIEINNCF_00875	3.42e-165	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PIEINNCF_00876	2.48e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
PIEINNCF_00877	3.18e-106	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
PIEINNCF_00879	1.71e-209	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_00880	1.8e-275	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PIEINNCF_00881	8.04e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PIEINNCF_00882	8.14e-194	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PIEINNCF_00883	5.54e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
PIEINNCF_00884	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PIEINNCF_00885	1.97e-124	-	-	-	K	-	-	-	Cupin domain
PIEINNCF_00886	9.1e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PIEINNCF_00887	1.44e-189	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIEINNCF_00888	2.88e-187	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIEINNCF_00889	9.91e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIEINNCF_00891	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
PIEINNCF_00892	1.82e-144	-	-	-	K	-	-	-	Transcriptional regulator
PIEINNCF_00893	1.72e-236	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PIEINNCF_00894	4.45e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PIEINNCF_00895	9e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PIEINNCF_00896	5.49e-215	ybbR	-	-	S	-	-	-	YbbR-like protein
PIEINNCF_00897	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PIEINNCF_00898	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PIEINNCF_00900	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
PIEINNCF_00901	3.35e-106	-	-	-	S	-	-	-	VanZ like family
PIEINNCF_00902	3.39e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
PIEINNCF_00903	1.02e-196	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
PIEINNCF_00904	3.76e-91	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
PIEINNCF_00905	5.31e-97	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
PIEINNCF_00906	1e-35	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
PIEINNCF_00908	3.85e-31	-	-	-	-	-	-	-	-
PIEINNCF_00909	3.2e-23	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
PIEINNCF_00911	6.18e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
PIEINNCF_00912	2.1e-81	-	-	-	-	-	-	-	-
PIEINNCF_00913	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PIEINNCF_00914	7.51e-191	arbV	-	-	I	-	-	-	Phosphate acyltransferases
PIEINNCF_00915	8.22e-212	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
PIEINNCF_00916	4e-234	arbY	-	-	M	-	-	-	family 8
PIEINNCF_00917	7.6e-213	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
PIEINNCF_00918	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PIEINNCF_00920	1.49e-172	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIEINNCF_00921	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_00922	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_00923	2.36e-130	-	-	-	S	-	-	-	Phage portal protein
PIEINNCF_00924	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
PIEINNCF_00925	1.65e-58	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PIEINNCF_00926	2.3e-23	-	-	-	-	-	-	-	-
PIEINNCF_00927	1.4e-35	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
PIEINNCF_00928	1.26e-52	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PIEINNCF_00930	9.31e-93	-	-	-	S	-	-	-	SdpI/YhfL protein family
PIEINNCF_00931	3.55e-174	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
PIEINNCF_00932	0.0	yclK	-	-	T	-	-	-	Histidine kinase
PIEINNCF_00933	3.29e-97	-	-	-	S	-	-	-	acetyltransferase
PIEINNCF_00934	5.2e-20	-	-	-	-	-	-	-	-
PIEINNCF_00935	1.27e-94	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
PIEINNCF_00936	8.83e-88	-	-	-	-	-	-	-	-
PIEINNCF_00937	8.56e-74	-	-	-	-	-	-	-	-
PIEINNCF_00938	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
PIEINNCF_00940	9.47e-264	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
PIEINNCF_00941	7.09e-180	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
PIEINNCF_00942	5.65e-46	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
PIEINNCF_00943	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
PIEINNCF_00944	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PIEINNCF_00945	4.26e-271	camS	-	-	S	-	-	-	sex pheromone
PIEINNCF_00946	3.61e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIEINNCF_00947	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PIEINNCF_00948	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIEINNCF_00949	4.97e-248	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
PIEINNCF_00950	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIEINNCF_00951	9.24e-281	yttB	-	-	EGP	-	-	-	Major Facilitator
PIEINNCF_00952	7.24e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PIEINNCF_00953	1.21e-210	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
PIEINNCF_00954	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PIEINNCF_00955	0.0	-	-	-	EGP	-	-	-	Major Facilitator
PIEINNCF_00956	2.85e-103	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
PIEINNCF_00957	2.87e-213	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PIEINNCF_00958	1.37e-165	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
PIEINNCF_00959	1.24e-39	-	-	-	-	-	-	-	-
PIEINNCF_00960	1.02e-179	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PIEINNCF_00961	9.39e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
PIEINNCF_00962	1.9e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
PIEINNCF_00963	2.69e-227	mocA	-	-	S	-	-	-	Oxidoreductase
PIEINNCF_00964	4.41e-289	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
PIEINNCF_00965	1.6e-73	chbA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
PIEINNCF_00966	7.45e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
PIEINNCF_00968	1.04e-06	-	-	-	-	-	-	-	-
PIEINNCF_00969	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PIEINNCF_00970	1.41e-306	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
PIEINNCF_00971	2.96e-144	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIEINNCF_00973	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
PIEINNCF_00974	1.38e-229	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
PIEINNCF_00975	1.24e-103	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PIEINNCF_00976	1.16e-204	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
PIEINNCF_00977	3.4e-255	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PIEINNCF_00979	1.02e-20	-	-	-	-	-	-	-	-
PIEINNCF_00980	1.09e-253	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
PIEINNCF_00981	1.31e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PIEINNCF_00982	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_00983	7.8e-122	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIEINNCF_00984	3.72e-152	licT2	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PIEINNCF_00985	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
PIEINNCF_00986	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PIEINNCF_00987	1.73e-219	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
PIEINNCF_00988	2.1e-133	-	-	-	-	-	-	-	-
PIEINNCF_00989	8.49e-217	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
PIEINNCF_00991	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
PIEINNCF_00992	9.32e-107	yvbK	-	-	K	-	-	-	GNAT family
PIEINNCF_00993	1.45e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
PIEINNCF_00994	2.27e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PIEINNCF_00995	3.09e-303	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
PIEINNCF_00996	6.67e-261	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PIEINNCF_00997	9.74e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PIEINNCF_00998	7.65e-136	-	-	-	-	-	-	-	-
PIEINNCF_00999	6.04e-137	-	-	-	-	-	-	-	-
PIEINNCF_01000	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PIEINNCF_01001	4.55e-143	vanZ	-	-	V	-	-	-	VanZ like family
PIEINNCF_01002	4.66e-196	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PIEINNCF_01003	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PIEINNCF_01004	1.79e-289	-	-	-	L	-	-	-	Pfam:Integrase_AP2
PIEINNCF_01005	4.53e-41	-	-	-	-	-	-	-	-
PIEINNCF_01006	1.1e-89	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
PIEINNCF_01009	7.46e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
PIEINNCF_01010	4e-91	-	-	-	E	-	-	-	Zn peptidase
PIEINNCF_01011	3.11e-73	-	-	-	K	-	-	-	Helix-turn-helix domain
PIEINNCF_01012	7.53e-10	-	-	-	K	-	-	-	sequence-specific DNA binding
PIEINNCF_01015	7.71e-128	-	-	-	-	-	-	-	-
PIEINNCF_01017	5.97e-22	-	-	-	-	-	-	-	-
PIEINNCF_01019	1.33e-196	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
PIEINNCF_01020	5.54e-192	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
PIEINNCF_01021	1.61e-193	-	-	-	L	-	-	-	Replication initiation and membrane attachment
PIEINNCF_01022	1.14e-87	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PIEINNCF_01024	6.14e-09	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PIEINNCF_01025	7.13e-60	-	-	-	-	-	-	-	-
PIEINNCF_01026	4.46e-42	-	-	-	-	-	-	-	-
PIEINNCF_01027	2.27e-86	-	-	-	S	-	-	-	magnesium ion binding
PIEINNCF_01032	2.12e-99	-	-	-	-	-	-	-	-
PIEINNCF_01034	6.73e-41	-	-	-	S	-	-	-	Beta protein
PIEINNCF_01035	2.27e-50	-	-	-	S	-	-	-	GcrA cell cycle regulator
PIEINNCF_01036	2.96e-182	-	-	-	S	-	-	-	GcrA cell cycle regulator
PIEINNCF_01038	4.01e-118	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
PIEINNCF_01039	1.68e-313	-	-	-	S	-	-	-	Terminase-like family
PIEINNCF_01040	0.0	-	-	-	S	-	-	-	Phage portal protein
PIEINNCF_01041	3.82e-229	-	-	-	S	-	-	-	head morphogenesis protein, SPP1 gp7 family
PIEINNCF_01042	1.26e-137	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
PIEINNCF_01043	1.38e-230	gpG	-	-	-	-	-	-	-
PIEINNCF_01044	3.07e-72	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PIEINNCF_01045	1.7e-60	-	-	-	-	-	-	-	-
PIEINNCF_01046	3.64e-74	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
PIEINNCF_01047	1.36e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF3168)
PIEINNCF_01048	1.34e-130	-	-	-	S	-	-	-	Phage tail tube protein
PIEINNCF_01049	4.64e-65	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
PIEINNCF_01050	6.39e-73	-	-	-	-	-	-	-	-
PIEINNCF_01051	0.0	-	-	-	S	-	-	-	phage tail tape measure protein
PIEINNCF_01052	5.17e-137	-	-	-	S	-	-	-	Phage tail protein
PIEINNCF_01053	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_01054	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_01055	1.54e-179	-	-	-	S	-	-	-	Phage tail protein
PIEINNCF_01056	0.0	-	-	-	S	-	-	-	cellulase activity
PIEINNCF_01059	3.86e-70	-	-	-	-	-	-	-	-
PIEINNCF_01060	1.61e-83	hol	-	-	S	-	-	-	Bacteriophage holin
PIEINNCF_01061	1.6e-108	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PIEINNCF_01062	2.21e-181	-	-	-	S	-	-	-	Domain of unknown function DUF1829
PIEINNCF_01063	2.12e-63	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
PIEINNCF_01065	4.65e-195	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
PIEINNCF_01066	1.26e-102	-	-	-	S	-	-	-	Pfam Transposase IS66
PIEINNCF_01067	2.76e-294	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
PIEINNCF_01068	1.48e-218	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
PIEINNCF_01069	5.68e-110	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
PIEINNCF_01071	2.46e-102	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
PIEINNCF_01072	1.53e-19	-	-	-	-	-	-	-	-
PIEINNCF_01073	3.11e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
PIEINNCF_01074	4.36e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PIEINNCF_01075	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PIEINNCF_01082	6.57e-70	-	-	-	T	-	-	-	Virulence-associated protein E
PIEINNCF_01083	1.92e-94	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
PIEINNCF_01089	7.5e-37	-	-	-	S	-	-	-	Phage regulatory protein
PIEINNCF_01092	6.39e-152	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIEINNCF_01095	2.12e-165	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
PIEINNCF_01096	2.61e-154	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIEINNCF_01097	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_01098	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PIEINNCF_01099	2.13e-180	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
PIEINNCF_01100	3.74e-208	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
PIEINNCF_01101	9.13e-252	ampC	-	-	V	-	-	-	Beta-lactamase
PIEINNCF_01102	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
PIEINNCF_01103	4.41e-143	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
PIEINNCF_01104	8.62e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PIEINNCF_01105	6.65e-196	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PIEINNCF_01106	9.87e-238	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PIEINNCF_01107	4.49e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PIEINNCF_01108	3.05e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PIEINNCF_01109	1.23e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PIEINNCF_01110	2.57e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIEINNCF_01111	1.13e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PIEINNCF_01112	1.32e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIEINNCF_01113	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PIEINNCF_01114	1.92e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PIEINNCF_01115	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PIEINNCF_01116	1.88e-91	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PIEINNCF_01117	8.38e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
PIEINNCF_01118	4.12e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
PIEINNCF_01119	1.37e-26	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
PIEINNCF_01120	1.14e-72	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
PIEINNCF_01121	9.8e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
PIEINNCF_01122	3.32e-284	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
PIEINNCF_01123	4.19e-65	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
PIEINNCF_01124	3.19e-284	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PIEINNCF_01125	1.88e-186	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PIEINNCF_01127	8.04e-192	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PIEINNCF_01128	3.46e-242	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PIEINNCF_01129	1.31e-149	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIEINNCF_01130	4.15e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
PIEINNCF_01131	9.53e-244	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
PIEINNCF_01132	2.82e-279	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PIEINNCF_01133	4.94e-103	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
PIEINNCF_01134	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
PIEINNCF_01135	4.73e-31	-	-	-	-	-	-	-	-
PIEINNCF_01136	9.85e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PIEINNCF_01137	4.31e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
PIEINNCF_01138	1.09e-144	yhfA	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
PIEINNCF_01139	1.56e-199	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIEINNCF_01140	4.74e-107	uspA	-	-	T	-	-	-	universal stress protein
PIEINNCF_01141	1.65e-52	-	-	-	-	-	-	-	-
PIEINNCF_01143	5.56e-305	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PIEINNCF_01144	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
PIEINNCF_01145	1.6e-98	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PIEINNCF_01146	1.65e-138	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
PIEINNCF_01147	1.02e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
PIEINNCF_01148	4.62e-193	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PIEINNCF_01149	4.46e-156	-	-	-	G	-	-	-	alpha-ribazole phosphatase activity
PIEINNCF_01150	9.85e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PIEINNCF_01151	5.8e-219	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
PIEINNCF_01152	2.93e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
PIEINNCF_01153	2.05e-173	-	-	-	F	-	-	-	deoxynucleoside kinase
PIEINNCF_01154	6.71e-202	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
PIEINNCF_01155	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PIEINNCF_01156	1.19e-200	-	-	-	T	-	-	-	GHKL domain
PIEINNCF_01157	2.12e-153	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
PIEINNCF_01158	6.65e-208	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PIEINNCF_01159	1.92e-130	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PIEINNCF_01160	6.77e-66	-	-	-	K	-	-	-	Transcriptional regulator
PIEINNCF_01161	2.68e-121	-	-	-	K	-	-	-	Transcriptional regulator
PIEINNCF_01162	1.31e-71	yphH	-	-	S	-	-	-	Cupin domain
PIEINNCF_01163	1.07e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
PIEINNCF_01164	6.15e-146	-	-	-	GM	-	-	-	NAD(P)H-binding
PIEINNCF_01165	1.12e-53	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PIEINNCF_01166	1.93e-157	gst	2.5.1.18	-	O	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	ko00000,ko00001,ko01000,ko02000	Glutathione S-transferase, C-terminal domain
PIEINNCF_01167	1.98e-147	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
PIEINNCF_01168	7.95e-219	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIEINNCF_01169	3.03e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIEINNCF_01170	7.56e-160	-	-	-	T	-	-	-	Histidine kinase
PIEINNCF_01171	4.62e-31	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
PIEINNCF_01172	4.28e-67	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
PIEINNCF_01173	3.72e-194	-	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIEINNCF_01174	1.71e-196	fbpC	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	TOBE domain
PIEINNCF_01175	8.21e-314	sfuB	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIEINNCF_01176	2.81e-197	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PIEINNCF_01177	1.63e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
PIEINNCF_01178	1.29e-192	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PIEINNCF_01179	1.58e-121	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
PIEINNCF_01180	4.02e-147	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PIEINNCF_01181	4.83e-276	-	-	-	-	-	-	-	-
PIEINNCF_01182	2.97e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PIEINNCF_01183	1.57e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
PIEINNCF_01184	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
PIEINNCF_01185	3.47e-70	-	-	-	-	-	-	-	-
PIEINNCF_01187	3.3e-84	-	-	-	-	-	-	-	-
PIEINNCF_01188	6.09e-65	-	-	-	-	-	-	-	-
PIEINNCF_01189	1.26e-07	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
PIEINNCF_01190	1.35e-301	-	-	-	L	ko:K07485	-	ko00000	Transposase
PIEINNCF_01191	5.31e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PIEINNCF_01192	1.68e-109	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
PIEINNCF_01193	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PIEINNCF_01194	2.04e-270	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PIEINNCF_01195	9.99e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PIEINNCF_01196	1.24e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PIEINNCF_01197	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PIEINNCF_01198	1.95e-307	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PIEINNCF_01199	1.98e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PIEINNCF_01200	1.97e-152	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
PIEINNCF_01201	4.82e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
PIEINNCF_01202	1.88e-191	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
PIEINNCF_01203	2.9e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
PIEINNCF_01204	4.46e-147	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PIEINNCF_01205	2.47e-181	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
PIEINNCF_01206	4.79e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PIEINNCF_01207	3.29e-146	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
PIEINNCF_01208	2.32e-193	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PIEINNCF_01209	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIEINNCF_01210	7.11e-60	-	-	-	-	-	-	-	-
PIEINNCF_01211	1.61e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PIEINNCF_01212	6.77e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PIEINNCF_01213	1.6e-68	ftsL	-	-	D	-	-	-	cell division protein FtsL
PIEINNCF_01214	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PIEINNCF_01215	1.33e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PIEINNCF_01216	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PIEINNCF_01217	1.15e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PIEINNCF_01218	1.45e-200	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PIEINNCF_01219	3.39e-310	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PIEINNCF_01220	3.25e-291	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PIEINNCF_01221	7.24e-102	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PIEINNCF_01222	5.58e-60	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	integral membrane protein
PIEINNCF_01223	8.38e-186	ylmH	-	-	S	-	-	-	S4 domain protein
PIEINNCF_01224	8.49e-120	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
PIEINNCF_01225	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PIEINNCF_01226	4.62e-48	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
PIEINNCF_01227	5.93e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PIEINNCF_01228	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
PIEINNCF_01229	1.03e-269	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
PIEINNCF_01230	8.03e-151	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
PIEINNCF_01231	4.31e-123	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
PIEINNCF_01232	1.42e-39	-	-	-	-	-	-	-	-
PIEINNCF_01233	1.95e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PIEINNCF_01234	2.81e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PIEINNCF_01235	7.02e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
PIEINNCF_01236	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
PIEINNCF_01237	7.08e-305	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PIEINNCF_01238	1.91e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
PIEINNCF_01239	1.62e-151	-	-	-	S	-	-	-	repeat protein
PIEINNCF_01240	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PIEINNCF_01241	1.65e-311	-	-	-	S	-	-	-	Sterol carrier protein domain
PIEINNCF_01242	1.15e-232	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PIEINNCF_01243	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIEINNCF_01244	2.02e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
PIEINNCF_01245	1.11e-95	-	-	-	-	-	-	-	-
PIEINNCF_01246	7.04e-63	-	-	-	-	-	-	-	-
PIEINNCF_01247	4.82e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PIEINNCF_01248	1.47e-111	-	-	-	S	-	-	-	E1-E2 ATPase
PIEINNCF_01249	1.42e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
PIEINNCF_01250	1.15e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
PIEINNCF_01251	0.0	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PIEINNCF_01252	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
PIEINNCF_01253	4.32e-202	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
PIEINNCF_01254	6.15e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
PIEINNCF_01255	3.56e-189	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
PIEINNCF_01256	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
PIEINNCF_01257	3.35e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PIEINNCF_01258	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PIEINNCF_01259	8.46e-84	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
PIEINNCF_01260	9.93e-130	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
PIEINNCF_01261	4.38e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PIEINNCF_01262	1.82e-233	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PIEINNCF_01263	4.24e-147	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
PIEINNCF_01264	1.55e-155	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PIEINNCF_01265	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PIEINNCF_01266	7.21e-222	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PIEINNCF_01267	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PIEINNCF_01268	5e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PIEINNCF_01269	5.41e-62	-	-	-	-	-	-	-	-
PIEINNCF_01270	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIEINNCF_01271	1.59e-212	-	-	-	S	-	-	-	Tetratricopeptide repeat
PIEINNCF_01272	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PIEINNCF_01273	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
PIEINNCF_01274	9.55e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PIEINNCF_01275	1.19e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PIEINNCF_01276	2.74e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
PIEINNCF_01277	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
PIEINNCF_01278	3.33e-28	-	-	-	-	-	-	-	-
PIEINNCF_01279	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PIEINNCF_01280	1.09e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_01281	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PIEINNCF_01282	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
PIEINNCF_01283	2.76e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PIEINNCF_01284	2.78e-170	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
PIEINNCF_01285	1.13e-307	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PIEINNCF_01286	0.0	oatA	-	-	I	-	-	-	Acyltransferase
PIEINNCF_01287	2.71e-233	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PIEINNCF_01288	1.23e-181	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
PIEINNCF_01289	2.47e-65	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
PIEINNCF_01290	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PIEINNCF_01291	1.35e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
PIEINNCF_01292	6.3e-123	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
PIEINNCF_01293	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
PIEINNCF_01294	7.08e-184	-	-	-	-	-	-	-	-
PIEINNCF_01295	8.1e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
PIEINNCF_01296	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
PIEINNCF_01297	2.21e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PIEINNCF_01298	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
PIEINNCF_01299	1.35e-301	-	-	-	L	ko:K07485	-	ko00000	Transposase
PIEINNCF_01300	4.31e-95	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
PIEINNCF_01301	5.96e-207	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
PIEINNCF_01302	9.95e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
PIEINNCF_01303	1.59e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIEINNCF_01304	1.07e-159	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PIEINNCF_01305	8.74e-139	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PIEINNCF_01306	1.1e-175	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PIEINNCF_01307	1.52e-123	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PIEINNCF_01308	1.16e-60	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
PIEINNCF_01309	6.4e-235	-	-	-	S	-	-	-	Helix-turn-helix domain
PIEINNCF_01310	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PIEINNCF_01311	1.68e-104	-	-	-	M	-	-	-	Lysin motif
PIEINNCF_01312	2.04e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
PIEINNCF_01313	3.47e-303	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PIEINNCF_01314	7.41e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PIEINNCF_01315	1.2e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PIEINNCF_01316	1.52e-302	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
PIEINNCF_01317	8.71e-200	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIEINNCF_01318	1.07e-283	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PIEINNCF_01319	2.95e-110	-	-	-	-	-	-	-	-
PIEINNCF_01320	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_01321	2e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PIEINNCF_01322	3.64e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PIEINNCF_01323	1.83e-148	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
PIEINNCF_01324	4.9e-190	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
PIEINNCF_01325	4.85e-196	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PIEINNCF_01326	3.05e-145	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
PIEINNCF_01327	3.02e-111	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PIEINNCF_01328	2.95e-54	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
PIEINNCF_01329	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
PIEINNCF_01330	1.27e-63	-	-	-	K	-	-	-	Helix-turn-helix domain
PIEINNCF_01331	2.53e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PIEINNCF_01332	4.13e-178	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIEINNCF_01333	6.07e-185	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
PIEINNCF_01334	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PIEINNCF_01335	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PIEINNCF_01336	1.66e-216	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
PIEINNCF_01337	2.06e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PIEINNCF_01338	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PIEINNCF_01339	5.38e-219	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PIEINNCF_01340	6.92e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PIEINNCF_01342	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIEINNCF_01343	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIEINNCF_01344	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
PIEINNCF_01345	2.56e-217	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PIEINNCF_01346	1.06e-231	-	-	-	K	-	-	-	LysR substrate binding domain
PIEINNCF_01347	3.24e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
PIEINNCF_01348	2.86e-267	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
PIEINNCF_01349	7.18e-79	-	-	-	-	-	-	-	-
PIEINNCF_01350	5.93e-186	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
PIEINNCF_01351	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_01352	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_01353	1.33e-122	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
PIEINNCF_01354	2.81e-71	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_01355	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PIEINNCF_01356	6.89e-107	-	-	-	L	-	-	-	Transposase DDE domain
PIEINNCF_01357	8.2e-41	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_01358	1.42e-218	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
PIEINNCF_01359	8.31e-158	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
PIEINNCF_01360	4.63e-273	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
PIEINNCF_01361	8.72e-64	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIEINNCF_01362	1.73e-93	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIEINNCF_01363	2.92e-144	-	-	-	C	-	-	-	Nitroreductase family
PIEINNCF_01364	3.43e-260	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PIEINNCF_01365	6.09e-70	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
PIEINNCF_01366	1.01e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PIEINNCF_01367	2.46e-170	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PIEINNCF_01368	1.32e-158	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PIEINNCF_01369	4.4e-95	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PIEINNCF_01370	6.23e-133	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
PIEINNCF_01371	1.46e-289	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PIEINNCF_01372	1.56e-277	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PIEINNCF_01373	1.4e-260	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PIEINNCF_01374	2.36e-129	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
PIEINNCF_01375	2.95e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
PIEINNCF_01376	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
PIEINNCF_01377	1.73e-66	-	-	-	S	-	-	-	MazG-like family
PIEINNCF_01378	1.85e-248	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PIEINNCF_01379	9.22e-121	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PIEINNCF_01380	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_01381	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_01382	3.64e-95	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PIEINNCF_01383	2.63e-286	bfmBB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
PIEINNCF_01384	5.05e-233	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
PIEINNCF_01385	5.29e-238	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
PIEINNCF_01386	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
PIEINNCF_01387	3.87e-262	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Acetokinase family
PIEINNCF_01388	3.36e-188	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Phosphate acetyl/butaryl transferase
PIEINNCF_01389	1.45e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PIEINNCF_01390	4.62e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PIEINNCF_01391	3.68e-198	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PIEINNCF_01392	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PIEINNCF_01393	1.78e-265	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PIEINNCF_01394	1.21e-303	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PIEINNCF_01395	7.64e-229	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PIEINNCF_01396	1.64e-299	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
PIEINNCF_01397	1.05e-125	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PIEINNCF_01398	5.18e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PIEINNCF_01399	2.41e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PIEINNCF_01400	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PIEINNCF_01401	8.5e-61	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
PIEINNCF_01402	2.37e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
PIEINNCF_01403	2.09e-143	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
PIEINNCF_01404	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIEINNCF_01405	3.85e-63	-	-	-	-	-	-	-	-
PIEINNCF_01406	0.0	-	-	-	S	-	-	-	Mga helix-turn-helix domain
PIEINNCF_01407	8.72e-52	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
PIEINNCF_01408	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIEINNCF_01409	1.03e-240	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIEINNCF_01410	3.31e-207	lysR	-	-	K	-	-	-	Transcriptional regulator
PIEINNCF_01411	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PIEINNCF_01412	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
PIEINNCF_01413	8.85e-47	-	-	-	-	-	-	-	-
PIEINNCF_01414	2.2e-223	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PIEINNCF_01415	1.1e-276	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
PIEINNCF_01417	7.09e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PIEINNCF_01418	6.54e-138	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
PIEINNCF_01419	1.47e-156	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PIEINNCF_01420	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
PIEINNCF_01421	5.94e-111	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
PIEINNCF_01422	7.61e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PIEINNCF_01423	3.19e-146	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
PIEINNCF_01424	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
PIEINNCF_01425	4.67e-279	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
PIEINNCF_01426	3.5e-112	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
PIEINNCF_01428	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
PIEINNCF_01429	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
PIEINNCF_01430	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PIEINNCF_01431	6.21e-214	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
PIEINNCF_01432	4.27e-228	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
PIEINNCF_01433	5.33e-243	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PIEINNCF_01434	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
PIEINNCF_01435	1.54e-222	-	-	-	-	-	-	-	-
PIEINNCF_01436	2.61e-183	-	-	-	-	-	-	-	-
PIEINNCF_01437	2.32e-79	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PIEINNCF_01438	2.03e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
PIEINNCF_01439	8.08e-191	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PIEINNCF_01440	1.33e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
PIEINNCF_01441	9.19e-249	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PIEINNCF_01442	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PIEINNCF_01443	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
PIEINNCF_01444	1.48e-219	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
PIEINNCF_01445	3.06e-283	sip	-	-	L	-	-	-	Phage integrase family
PIEINNCF_01448	2.49e-257	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PIEINNCF_01449	1.55e-63	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
PIEINNCF_01450	8.63e-42	-	-	-	-	-	-	-	-
PIEINNCF_01453	6.89e-107	-	-	-	L	-	-	-	Transposase DDE domain
PIEINNCF_01454	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PIEINNCF_01455	2.17e-65	-	-	-	S	-	-	-	cellulase activity
PIEINNCF_01456	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
PIEINNCF_01457	0.0	-	-	-	S	-	-	-	Phage tail protein
PIEINNCF_01458	0.0	-	-	-	D	-	-	-	domain protein
PIEINNCF_01459	3.48e-189	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PIEINNCF_01460	8.54e-32	-	-	-	-	-	-	-	-
PIEINNCF_01461	9.47e-70	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
PIEINNCF_01462	2.85e-100	-	-	-	S	-	-	-	Phage tail tube protein
PIEINNCF_01463	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_01464	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_01465	2.59e-24	-	-	-	S	-	-	-	Phage tail tube protein
PIEINNCF_01466	2.82e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
PIEINNCF_01467	1.69e-83	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
PIEINNCF_01468	2.17e-65	-	-	-	S	-	-	-	Phage head-tail joining protein
PIEINNCF_01469	1.29e-39	-	-	-	-	-	-	-	-
PIEINNCF_01470	3.84e-224	-	-	-	S	-	-	-	Phage capsid family
PIEINNCF_01471	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_01472	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_01473	9.65e-83	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
PIEINNCF_01474	4.64e-255	-	-	-	S	-	-	-	Phage portal protein
PIEINNCF_01476	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
PIEINNCF_01477	3.31e-94	-	-	-	L	-	-	-	Phage terminase, small subunit
PIEINNCF_01478	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PIEINNCF_01479	6.89e-107	-	-	-	L	-	-	-	Transposase DDE domain
PIEINNCF_01480	4.38e-62	-	-	-	L	-	-	-	Single-strand binding protein family
PIEINNCF_01481	5.05e-58	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_01482	1.63e-196	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_01483	1.53e-112	-	-	-	-	-	-	-	-
PIEINNCF_01484	1.67e-11	-	-	-	S	-	-	-	sequence-specific DNA binding transcription factor activity
PIEINNCF_01487	3.22e-15	-	-	-	-	-	-	-	-
PIEINNCF_01488	1.44e-53	-	-	-	-	-	-	-	-
PIEINNCF_01489	7.8e-21	-	-	-	-	-	-	-	-
PIEINNCF_01490	2.87e-181	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PIEINNCF_01491	2.76e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PIEINNCF_01492	1.38e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PIEINNCF_01493	6.78e-82	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
PIEINNCF_01494	1.03e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PIEINNCF_01495	8.02e-230	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
PIEINNCF_01496	5.18e-88	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
PIEINNCF_01497	3.98e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
PIEINNCF_01498	8.44e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PIEINNCF_01499	2.48e-210	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PIEINNCF_01500	3.1e-216	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIEINNCF_01501	7.27e-106	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
PIEINNCF_01502	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PIEINNCF_01503	4.43e-309	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PIEINNCF_01504	4.56e-47	XK27_04345	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
PIEINNCF_01505	0.0	-	-	-	-	-	-	-	-
PIEINNCF_01506	1.39e-200	-	-	-	V	-	-	-	ABC transporter
PIEINNCF_01507	2.36e-109	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
PIEINNCF_01508	8.06e-314	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
PIEINNCF_01509	3.87e-150	-	-	-	J	-	-	-	HAD-hyrolase-like
PIEINNCF_01510	1.59e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PIEINNCF_01511	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PIEINNCF_01512	5.49e-58	-	-	-	-	-	-	-	-
PIEINNCF_01513	7.37e-169	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PIEINNCF_01514	3.36e-220	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
PIEINNCF_01515	1.42e-112	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
PIEINNCF_01516	3.48e-141	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
PIEINNCF_01517	2.23e-50	-	-	-	-	-	-	-	-
PIEINNCF_01518	8.05e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
PIEINNCF_01519	6.1e-27	-	-	-	-	-	-	-	-
PIEINNCF_01520	1.72e-64	-	-	-	-	-	-	-	-
PIEINNCF_01521	1.47e-30	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIEINNCF_01522	2.06e-17	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIEINNCF_01526	5.65e-96	-	-	-	O	-	-	-	AAA domain (Cdc48 subfamily)
PIEINNCF_01527	1.02e-62	-	-	-	S	-	-	-	Flavodoxin-like fold
PIEINNCF_01528	4.08e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIEINNCF_01529	1.71e-198	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
PIEINNCF_01530	1.66e-71	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
PIEINNCF_01531	2.01e-118	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PIEINNCF_01532	9.84e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PIEINNCF_01533	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
PIEINNCF_01534	8.85e-76	-	-	-	-	-	-	-	-
PIEINNCF_01535	1.97e-107	-	-	-	S	-	-	-	ASCH
PIEINNCF_01536	1.32e-33	-	-	-	-	-	-	-	-
PIEINNCF_01537	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PIEINNCF_01538	2.42e-63	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
PIEINNCF_01539	2.88e-176	-	-	-	V	-	-	-	ABC transporter transmembrane region
PIEINNCF_01540	2.22e-259	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PIEINNCF_01541	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PIEINNCF_01542	3.18e-127	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PIEINNCF_01543	1.6e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PIEINNCF_01544	2.08e-286	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
PIEINNCF_01545	7.37e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PIEINNCF_01546	1.64e-212	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PIEINNCF_01547	1.49e-181	terC	-	-	P	-	-	-	Integral membrane protein TerC family
PIEINNCF_01548	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PIEINNCF_01549	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PIEINNCF_01550	1.29e-60	ylxQ	-	-	J	-	-	-	ribosomal protein
PIEINNCF_01551	9.63e-61	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
PIEINNCF_01552	4.13e-277	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PIEINNCF_01553	1.33e-110	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
PIEINNCF_01554	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIEINNCF_01555	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PIEINNCF_01556	3.52e-292	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
PIEINNCF_01557	1.55e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
PIEINNCF_01558	5.24e-180	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PIEINNCF_01559	4.96e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PIEINNCF_01560	5.86e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PIEINNCF_01561	1.63e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PIEINNCF_01562	1.18e-182	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PIEINNCF_01563	5.38e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
PIEINNCF_01564	2.05e-168	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
PIEINNCF_01566	4.5e-59	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PIEINNCF_01567	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_01568	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_01569	8.43e-68	-	-	-	-	-	-	-	-
PIEINNCF_01573	4.88e-197	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
PIEINNCF_01574	3.44e-157	-	-	-	L	-	-	-	Helix-turn-helix domain
PIEINNCF_01581	5.82e-150	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
PIEINNCF_01583	4.49e-57	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIEINNCF_01584	2.15e-29	-	-	-	E	-	-	-	Zn peptidase
PIEINNCF_01586	2.31e-21	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PIEINNCF_01590	2.32e-24	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIEINNCF_01591	2.86e-67	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIEINNCF_01592	8.45e-160	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
PIEINNCF_01593	1.3e-290	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
PIEINNCF_01594	4.28e-181	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
PIEINNCF_01595	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIEINNCF_01596	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIEINNCF_01597	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
PIEINNCF_01598	2.96e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
PIEINNCF_01599	3.28e-28	-	-	-	-	-	-	-	-
PIEINNCF_01600	2e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PIEINNCF_01601	1.76e-185	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PIEINNCF_01602	1.25e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PIEINNCF_01603	1.55e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
PIEINNCF_01604	2.97e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PIEINNCF_01605	2.16e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PIEINNCF_01606	1.26e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PIEINNCF_01607	7.91e-70	-	-	-	-	-	-	-	-
PIEINNCF_01608	1.06e-231	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PIEINNCF_01609	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PIEINNCF_01610	2.8e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PIEINNCF_01611	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PIEINNCF_01612	1.16e-193	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIEINNCF_01613	3.2e-216	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIEINNCF_01614	1.62e-228	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIEINNCF_01615	3.49e-246	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIEINNCF_01616	3.21e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PIEINNCF_01617	1.35e-239	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PIEINNCF_01618	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PIEINNCF_01619	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
PIEINNCF_01620	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PIEINNCF_01621	2.29e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
PIEINNCF_01622	1.25e-164	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
PIEINNCF_01623	4.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PIEINNCF_01624	6.54e-220	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PIEINNCF_01625	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PIEINNCF_01626	5.22e-174	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
PIEINNCF_01627	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PIEINNCF_01628	1.13e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PIEINNCF_01629	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PIEINNCF_01630	4.94e-269	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PIEINNCF_01631	1.77e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PIEINNCF_01632	2.95e-147	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PIEINNCF_01633	9.51e-117	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
PIEINNCF_01634	1.11e-65	-	-	-	-	-	-	-	-
PIEINNCF_01636	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PIEINNCF_01637	4.19e-96	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PIEINNCF_01638	8.09e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
PIEINNCF_01639	1.28e-189	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PIEINNCF_01640	1.42e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIEINNCF_01641	2.12e-293	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIEINNCF_01642	5.21e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PIEINNCF_01643	5.53e-87	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PIEINNCF_01644	9.44e-99	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
PIEINNCF_01645	6.06e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PIEINNCF_01646	3.55e-258	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PIEINNCF_01647	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
PIEINNCF_01648	2.94e-73	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
PIEINNCF_01649	5.83e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PIEINNCF_01650	1.17e-16	-	-	-	-	-	-	-	-
PIEINNCF_01651	4.05e-38	-	-	-	-	-	-	-	-
PIEINNCF_01653	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PIEINNCF_01654	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PIEINNCF_01655	1.32e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
PIEINNCF_01656	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
PIEINNCF_01657	1.36e-303	ynbB	-	-	P	-	-	-	aluminum resistance
PIEINNCF_01658	1.09e-222	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PIEINNCF_01659	3.33e-35	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
PIEINNCF_01660	1.93e-96	yqhL	-	-	P	-	-	-	Rhodanese-like protein
PIEINNCF_01661	1.13e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
PIEINNCF_01662	6.79e-55	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
PIEINNCF_01663	5.43e-157	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
PIEINNCF_01664	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PIEINNCF_01665	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
PIEINNCF_01666	8.3e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
PIEINNCF_01667	2.04e-149	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
PIEINNCF_01668	1.33e-231	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PIEINNCF_01669	1.1e-164	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
PIEINNCF_01670	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PIEINNCF_01671	4.87e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
PIEINNCF_01672	7.4e-265	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PIEINNCF_01673	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIEINNCF_01674	3.55e-259	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PIEINNCF_01675	1.2e-87	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PIEINNCF_01676	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PIEINNCF_01677	4.47e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIEINNCF_01678	4.17e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
PIEINNCF_01679	2.58e-228	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIEINNCF_01680	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PIEINNCF_01681	1.01e-157	csrR	-	-	K	-	-	-	response regulator
PIEINNCF_01682	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PIEINNCF_01683	5.74e-52	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PIEINNCF_01684	3.14e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
PIEINNCF_01685	9.63e-270	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
PIEINNCF_01686	2.06e-179	yccK	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
PIEINNCF_01687	1.18e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PIEINNCF_01688	3.21e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
PIEINNCF_01689	2.72e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PIEINNCF_01690	3.25e-64	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
PIEINNCF_01691	5e-261	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
PIEINNCF_01692	2.22e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
PIEINNCF_01693	7.95e-220	ykcA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIEINNCF_01694	6.46e-242	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIEINNCF_01695	4.31e-157	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
PIEINNCF_01696	1.02e-229	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
PIEINNCF_01697	3.37e-129	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
PIEINNCF_01698	1.02e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PIEINNCF_01699	3.24e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
PIEINNCF_01700	7.46e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PIEINNCF_01701	2.7e-166	-	-	-	S	-	-	-	SseB protein N-terminal domain
PIEINNCF_01702	5.3e-70	-	-	-	-	-	-	-	-
PIEINNCF_01703	4.26e-133	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
PIEINNCF_01704	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PIEINNCF_01706	2.02e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
PIEINNCF_01707	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
PIEINNCF_01708	8.38e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PIEINNCF_01709	6.65e-131	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PIEINNCF_01710	1.03e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PIEINNCF_01711	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PIEINNCF_01712	4.05e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
PIEINNCF_01713	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PIEINNCF_01714	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PIEINNCF_01715	9.09e-149	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIEINNCF_01716	5.32e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
PIEINNCF_01717	5.99e-06	-	-	-	S	-	-	-	Small secreted protein
PIEINNCF_01718	8.13e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PIEINNCF_01719	1.84e-188	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
PIEINNCF_01720	1.69e-107	-	-	-	L	-	-	-	Transposase DDE domain
PIEINNCF_01721	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PIEINNCF_01722	2.38e-274	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PIEINNCF_01723	4.84e-172	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_01724	1.67e-99	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
PIEINNCF_01725	2.86e-81	-	-	-	S	-	-	-	YtxH-like protein
PIEINNCF_01726	5.26e-205	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PIEINNCF_01727	8.42e-232	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
PIEINNCF_01728	1.03e-72	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
PIEINNCF_01729	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PIEINNCF_01730	4.85e-194	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PIEINNCF_01731	3.31e-98	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PIEINNCF_01732	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PIEINNCF_01734	1.97e-88	-	-	-	-	-	-	-	-
PIEINNCF_01735	5.54e-30	-	-	-	-	-	-	-	-
PIEINNCF_01736	3.67e-227	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
PIEINNCF_01737	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
PIEINNCF_01738	1.44e-157	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PIEINNCF_01739	1.13e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PIEINNCF_01740	9.41e-176	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
PIEINNCF_01741	7.88e-121	traP	1.14.99.57, 6.2.1.3	-	S	ko:K01897,ko:K21481	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	heme oxygenase (decyclizing) activity
PIEINNCF_01742	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
PIEINNCF_01743	1.14e-177	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PIEINNCF_01744	1.57e-159	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
PIEINNCF_01745	1.21e-266	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
PIEINNCF_01746	2.56e-140	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PIEINNCF_01747	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
PIEINNCF_01748	3.93e-99	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
PIEINNCF_01749	6.39e-299	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
PIEINNCF_01750	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
PIEINNCF_01751	5.57e-129	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PIEINNCF_01752	7.21e-237	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
PIEINNCF_01753	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PIEINNCF_01754	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIEINNCF_01755	6.91e-165	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIEINNCF_01756	8.16e-53	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIEINNCF_01757	5.45e-171	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
PIEINNCF_01758	2.03e-272	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PIEINNCF_01759	2.66e-102	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PIEINNCF_01760	3.87e-135	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
PIEINNCF_01761	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PIEINNCF_01762	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PIEINNCF_01763	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
PIEINNCF_01764	9.5e-39	-	-	-	-	-	-	-	-
PIEINNCF_01765	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PIEINNCF_01766	3.36e-61	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
PIEINNCF_01768	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PIEINNCF_01769	2.05e-311	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
PIEINNCF_01770	4.17e-262	yueF	-	-	S	-	-	-	AI-2E family transporter
PIEINNCF_01771	9.31e-97	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
PIEINNCF_01772	1.11e-122	-	-	-	-	-	-	-	-
PIEINNCF_01773	1.1e-134	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
PIEINNCF_01774	6.84e-183	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
PIEINNCF_01775	0.0	frvR	-	-	K	ko:K02538,ko:K03483,ko:K09685,ko:K18531	-	ko00000,ko03000	transcriptional antiterminator
PIEINNCF_01776	6.46e-83	-	-	-	-	-	-	-	-
PIEINNCF_01777	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIEINNCF_01778	1.68e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
PIEINNCF_01779	2.13e-172	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
PIEINNCF_01780	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIEINNCF_01781	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEINNCF_01782	2.36e-111	-	-	-	-	-	-	-	-
PIEINNCF_01783	7.89e-66	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
PIEINNCF_01784	6.27e-67	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PIEINNCF_01785	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PIEINNCF_01786	7.46e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
PIEINNCF_01787	1.9e-266	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
PIEINNCF_01788	2.84e-265	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PIEINNCF_01789	7.23e-66	-	-	-	-	-	-	-	-
PIEINNCF_01790	3.33e-205	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
PIEINNCF_01791	4.44e-134	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
PIEINNCF_01792	1.52e-199	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	converts alpha-aldose to the beta-anomer
PIEINNCF_01793	3.11e-271	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PIEINNCF_01794	2.5e-131	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PIEINNCF_01796	1.4e-105	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
PIEINNCF_01797	2.34e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
PIEINNCF_01798	2.36e-167	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_01799	2.83e-188	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PIEINNCF_01800	1.43e-197	XK27_08835	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PIEINNCF_01801	2.77e-94	-	-	-	-	-	-	-	-
PIEINNCF_01802	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PIEINNCF_01803	1.97e-277	-	-	-	V	-	-	-	Beta-lactamase
PIEINNCF_01804	2.51e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PIEINNCF_01805	1.11e-280	-	-	-	V	-	-	-	Beta-lactamase
PIEINNCF_01806	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PIEINNCF_01807	1.62e-161	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
PIEINNCF_01808	6.12e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PIEINNCF_01809	1.6e-177	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PIEINNCF_01810	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
PIEINNCF_01813	8.48e-203	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PIEINNCF_01814	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
PIEINNCF_01815	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_01816	1.71e-87	-	-	-	-	-	-	-	-
PIEINNCF_01817	6.13e-100	-	-	-	S	-	-	-	function, without similarity to other proteins
PIEINNCF_01818	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
PIEINNCF_01819	1.46e-289	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
PIEINNCF_01820	8.15e-77	-	-	-	-	-	-	-	-
PIEINNCF_01821	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
PIEINNCF_01822	6.28e-25	-	-	-	S	-	-	-	Virus attachment protein p12 family
PIEINNCF_01823	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
PIEINNCF_01824	4.14e-91	-	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
PIEINNCF_01825	8.24e-168	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
PIEINNCF_01828	4.34e-151	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
PIEINNCF_01829	8.14e-79	-	-	-	S	-	-	-	MucBP domain
PIEINNCF_01830	9.73e-109	-	-	-	-	-	-	-	-
PIEINNCF_01833	5.19e-90	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
PIEINNCF_01836	1.45e-46	-	-	-	-	-	-	-	-
PIEINNCF_01837	5.43e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PIEINNCF_01838	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
PIEINNCF_01839	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
PIEINNCF_01840	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
PIEINNCF_01842	2.4e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
PIEINNCF_01843	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PIEINNCF_01844	4.81e-127	-	-	-	-	-	-	-	-
PIEINNCF_01845	8.44e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PIEINNCF_01846	7.89e-245	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
PIEINNCF_01847	3.26e-113	-	-	-	-	-	-	-	-
PIEINNCF_01848	1.43e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PIEINNCF_01849	6.98e-149	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PIEINNCF_01850	1.93e-202	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PIEINNCF_01851	1.25e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PIEINNCF_01852	4.98e-43	-	-	-	-	-	-	-	-
PIEINNCF_01853	7.43e-97	-	-	-	-	-	-	-	-
PIEINNCF_01854	1.99e-199	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PIEINNCF_01855	1.19e-162	citR	-	-	K	-	-	-	FCD
PIEINNCF_01856	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
PIEINNCF_01857	7.7e-120	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PIEINNCF_01858	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
PIEINNCF_01859	7.46e-201	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
PIEINNCF_01860	3.41e-65	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
PIEINNCF_01861	1.28e-229	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PIEINNCF_01862	3.26e-07	-	-	-	-	-	-	-	-
PIEINNCF_01863	1.13e-250	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
PIEINNCF_01864	7.19e-61	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
PIEINNCF_01865	9.08e-71	-	-	-	-	-	-	-	-
PIEINNCF_01866	1.43e-307	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
PIEINNCF_01867	3.61e-55	-	-	-	-	-	-	-	-
PIEINNCF_01868	2.68e-135	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
PIEINNCF_01869	2.1e-114	-	-	-	K	-	-	-	GNAT family
PIEINNCF_01870	3.16e-136	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
PIEINNCF_01871	1.13e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
PIEINNCF_01872	1.15e-111	ORF00048	-	-	-	-	-	-	-
PIEINNCF_01873	1.43e-173	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
PIEINNCF_01874	3.34e-215	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PIEINNCF_01875	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
PIEINNCF_01876	9.43e-146	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
PIEINNCF_01877	0.0	-	-	-	EGP	-	-	-	Major Facilitator
PIEINNCF_01878	2.35e-160	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PIEINNCF_01879	3.85e-236	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIEINNCF_01880	2.62e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
PIEINNCF_01881	1.26e-77	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
PIEINNCF_01882	1.87e-160	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PIEINNCF_01883	1.32e-15	-	-	-	-	-	-	-	-
PIEINNCF_01884	8.52e-155	-	-	-	-	-	-	-	-
PIEINNCF_01885	2.47e-111	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PIEINNCF_01886	1.18e-121	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PIEINNCF_01887	1.99e-205	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
PIEINNCF_01888	8.35e-256	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
PIEINNCF_01890	1.54e-222	-	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIEINNCF_01891	1.2e-214	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIEINNCF_01892	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
PIEINNCF_01893	2.16e-124	-	-	-	S	-	-	-	DJ-1/PfpI family
PIEINNCF_01894	2.12e-70	-	-	-	K	-	-	-	Transcriptional
PIEINNCF_01895	3.73e-49	-	-	-	-	-	-	-	-
PIEINNCF_01896	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PIEINNCF_01897	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
PIEINNCF_01899	9.28e-89	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PIEINNCF_01900	1.11e-19	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
PIEINNCF_01901	7.14e-310	-	-	-	M	-	-	-	LysM domain
PIEINNCF_01902	1.46e-95	-	-	-	M	-	-	-	LysM domain
PIEINNCF_01903	7.95e-172	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
PIEINNCF_01904	5.74e-166	-	-	-	K	-	-	-	DeoR C terminal sensor domain
PIEINNCF_01906	5.24e-66	lciIC	-	-	K	-	-	-	Helix-turn-helix domain
PIEINNCF_01907	3.11e-120	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
PIEINNCF_01909	4.96e-33	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
PIEINNCF_01913	9.98e-57	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
PIEINNCF_01914	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PIEINNCF_01915	2.3e-228	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
PIEINNCF_01917	2.38e-56	-	-	-	-	-	-	-	-
PIEINNCF_01918	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PIEINNCF_01919	1.44e-109	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
PIEINNCF_01920	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PIEINNCF_01921	7.47e-30	-	-	-	-	-	-	-	-
PIEINNCF_01922	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
PIEINNCF_01923	8.04e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PIEINNCF_01924	9.11e-106	yjhE	-	-	S	-	-	-	Phage tail protein
PIEINNCF_01925	1.55e-307	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PIEINNCF_01926	1.58e-237	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
PIEINNCF_01927	4.03e-164	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
PIEINNCF_01928	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PIEINNCF_01929	1.55e-173	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_01930	0.0	-	-	-	E	-	-	-	Amino Acid
PIEINNCF_01931	3.33e-209	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PIEINNCF_01932	4.57e-304	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PIEINNCF_01933	2.06e-202	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
PIEINNCF_01934	0.0	-	-	-	M	-	-	-	Sulfatase
PIEINNCF_01935	1.41e-303	-	-	-	L	ko:K07485	-	ko00000	Transposase
PIEINNCF_01936	8.04e-220	-	-	-	S	-	-	-	EpsG family
PIEINNCF_01937	6.33e-100	-	-	-	D	-	-	-	Capsular exopolysaccharide family
PIEINNCF_01938	1.46e-119	ywqC	-	-	M	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	capsule polysaccharide biosynthetic process
PIEINNCF_01939	3.04e-305	-	-	-	S	-	-	-	polysaccharide biosynthetic process
PIEINNCF_01940	2.54e-243	-	-	-	M	-	-	-	Glycosyl transferases group 1
PIEINNCF_01941	3.67e-127	tagF	2.7.8.12	-	M	ko:K09809,ko:K19046	-	ko00000,ko01000,ko02048	Glycosyl transferase, family 2
PIEINNCF_01942	4.22e-79	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PIEINNCF_01943	1.78e-296	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
PIEINNCF_01944	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PIEINNCF_01945	7.31e-220	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
PIEINNCF_01946	1.67e-144	-	-	-	M	-	-	-	Acyltransferase family
PIEINNCF_01947	1.43e-200	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
PIEINNCF_01948	1.82e-253	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PIEINNCF_01949	7.06e-117	-	-	-	-	-	-	-	-
PIEINNCF_01950	3.55e-312	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
PIEINNCF_01951	5.34e-162	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
PIEINNCF_01952	1.12e-138	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
PIEINNCF_01953	6.58e-225	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
PIEINNCF_01954	6.51e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIEINNCF_01955	1.44e-141	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIEINNCF_01956	2.05e-189	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PIEINNCF_01957	6.35e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_01958	2.2e-227	-	-	-	-	-	-	-	-
PIEINNCF_01960	3.91e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
PIEINNCF_01961	9.35e-15	-	-	-	-	-	-	-	-
PIEINNCF_01962	7.28e-144	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
PIEINNCF_01963	9.94e-90	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIEINNCF_01964	2.95e-187	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
PIEINNCF_01965	1.55e-312	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PIEINNCF_01966	7.63e-221	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PIEINNCF_01967	3.38e-72	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PIEINNCF_01968	3.12e-222	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PIEINNCF_01969	1.73e-212	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PIEINNCF_01970	6.94e-208	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PIEINNCF_01971	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PIEINNCF_01972	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
PIEINNCF_01973	3.28e-278	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
PIEINNCF_01974	1.6e-150	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PIEINNCF_01975	2.61e-89	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PIEINNCF_01976	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PIEINNCF_01977	3.55e-261	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
PIEINNCF_01978	5.79e-83	-	-	-	M	-	-	-	Sortase family
PIEINNCF_01979	9.47e-42	-	-	-	M	-	-	-	Sortase family
PIEINNCF_01980	1.29e-186	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIEINNCF_01981	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
PIEINNCF_01982	1.94e-86	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
PIEINNCF_01983	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
PIEINNCF_01984	1.9e-184	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
PIEINNCF_01985	4.96e-195	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PIEINNCF_01986	2.73e-227	-	-	-	L	ko:K07485	-	ko00000	Transposase
PIEINNCF_01987	3.65e-49	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PIEINNCF_01988	1.12e-98	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
PIEINNCF_01989	9.14e-141	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
PIEINNCF_01990	2.05e-90	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
PIEINNCF_01991	1.3e-83	-	-	-	M	-	-	-	Glycosyl transferases group 1
PIEINNCF_01992	3.02e-49	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PIEINNCF_01993	1.08e-28	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
PIEINNCF_01994	2.02e-264	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
PIEINNCF_01995	1.05e-250	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
PIEINNCF_01996	1.38e-141	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
PIEINNCF_01997	8.86e-162	epsB	-	-	M	-	-	-	biosynthesis protein
PIEINNCF_01998	3.16e-171	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PIEINNCF_01999	1.06e-169	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
PIEINNCF_02001	2.64e-56	-	-	-	L	-	-	-	AAA ATPase domain
PIEINNCF_02002	3.04e-39	-	-	-	L	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
PIEINNCF_02003	3.28e-66	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
PIEINNCF_02004	1.56e-257	-	-	-	L	ko:K07485	-	ko00000	Transposase
PIEINNCF_02006	4.2e-106	ccl	-	-	S	-	-	-	QueT transporter
PIEINNCF_02007	3.64e-160	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PIEINNCF_02008	2.1e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
PIEINNCF_02009	6.56e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
PIEINNCF_02010	2.15e-151	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
PIEINNCF_02011	2.59e-229	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIEINNCF_02012	4.99e-251	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIEINNCF_02013	1.74e-226	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIEINNCF_02014	5.7e-208	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIEINNCF_02015	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PIEINNCF_02016	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PIEINNCF_02017	4.1e-130	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PIEINNCF_02018	3.16e-169	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
PIEINNCF_02019	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
PIEINNCF_02020	4.87e-190	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
PIEINNCF_02021	2.39e-109	-	-	-	-	-	-	-	-
PIEINNCF_02022	6.31e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system cellobiose-specific component IIA
PIEINNCF_02023	2.54e-268	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
PIEINNCF_02024	6.33e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
PIEINNCF_02026	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEINNCF_02028	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PIEINNCF_02029	2.48e-172	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
PIEINNCF_02030	1.76e-177	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
PIEINNCF_02031	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
PIEINNCF_02032	1.45e-101	-	-	-	-	-	-	-	-
PIEINNCF_02033	1.32e-76	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PIEINNCF_02034	3.39e-186	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
PIEINNCF_02035	2.16e-130	hyuA	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
PIEINNCF_02036	2.03e-75	-	-	-	-	-	-	-	-
PIEINNCF_02037	6.13e-67	-	-	-	-	-	-	-	-
PIEINNCF_02038	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
PIEINNCF_02039	3.85e-85	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
PIEINNCF_02040	5.83e-222	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIEINNCF_02041	1.54e-97	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
PIEINNCF_02042	4.48e-271	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
PIEINNCF_02043	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
PIEINNCF_02045	4.08e-270	-	-	-	-	-	-	-	-
PIEINNCF_02046	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIEINNCF_02047	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PIEINNCF_02048	7.45e-233	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
PIEINNCF_02049	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
PIEINNCF_02050	3.47e-210	-	-	-	GM	-	-	-	NmrA-like family
PIEINNCF_02051	3.95e-297	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
PIEINNCF_02052	3.41e-184	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
PIEINNCF_02053	3.05e-194	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PIEINNCF_02054	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
PIEINNCF_02055	3.23e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PIEINNCF_02056	8.8e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PIEINNCF_02057	6.98e-284	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PIEINNCF_02058	8.26e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
PIEINNCF_02059	2.32e-207	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
PIEINNCF_02060	4.56e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
PIEINNCF_02061	1.38e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PIEINNCF_02062	3.96e-226	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PIEINNCF_02063	2.44e-99	-	-	-	K	-	-	-	Winged helix DNA-binding domain
PIEINNCF_02064	6.79e-95	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
PIEINNCF_02066	4.22e-245	-	-	-	E	-	-	-	Alpha/beta hydrolase family
PIEINNCF_02067	8.85e-287	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
PIEINNCF_02068	3.45e-64	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
PIEINNCF_02069	2.84e-88	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
PIEINNCF_02070	5.76e-14	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
PIEINNCF_02071	3.97e-213	-	-	-	S	-	-	-	Putative esterase
PIEINNCF_02072	4.3e-255	-	-	-	-	-	-	-	-
PIEINNCF_02073	6e-136	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
PIEINNCF_02074	2.4e-301	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
PIEINNCF_02075	6.45e-79	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
PIEINNCF_02076	5.71e-100	-	-	-	F	-	-	-	NUDIX domain
PIEINNCF_02077	4.68e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PIEINNCF_02078	4.74e-30	-	-	-	-	-	-	-	-
PIEINNCF_02079	8.98e-209	-	-	-	S	-	-	-	zinc-ribbon domain
PIEINNCF_02080	2.41e-261	pbpX	-	-	V	-	-	-	Beta-lactamase
PIEINNCF_02081	4.01e-240	ydbI	-	-	K	-	-	-	AI-2E family transporter
PIEINNCF_02082	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
PIEINNCF_02083	2.49e-165	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
PIEINNCF_02084	1.41e-85	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
PIEINNCF_02085	4.79e-222	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PIEINNCF_02086	3.31e-254	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PIEINNCF_02087	6.26e-143	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PIEINNCF_02088	7.08e-216	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
PIEINNCF_02089	5.82e-189	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
PIEINNCF_02090	9.19e-285	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
PIEINNCF_02091	1.39e-176	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
PIEINNCF_02092	2.6e-96	usp1	-	-	T	-	-	-	Universal stress protein family
PIEINNCF_02093	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
PIEINNCF_02094	2.12e-193	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PIEINNCF_02095	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
PIEINNCF_02096	1.31e-289	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
PIEINNCF_02097	9.28e-317	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PIEINNCF_02098	3.74e-269	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
PIEINNCF_02099	2.08e-48	-	-	-	-	-	-	-	-
PIEINNCF_02100	4.03e-48	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PIEINNCF_02101	5.57e-139	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PIEINNCF_02102	4.13e-225	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIEINNCF_02103	2.31e-277	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PIEINNCF_02104	9.93e-65	-	-	-	-	-	-	-	-
PIEINNCF_02105	3.52e-161	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
PIEINNCF_02106	1.62e-93	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
PIEINNCF_02107	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PIEINNCF_02109	1.66e-175	mprF	2.3.2.3	-	M	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	lysyltransferase activity
PIEINNCF_02111	1.82e-257	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PIEINNCF_02112	1.69e-203	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
PIEINNCF_02113	5.4e-225	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PIEINNCF_02114	1.58e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIEINNCF_02115	4.05e-211	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
PIEINNCF_02116	1.38e-275	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PIEINNCF_02117	2.78e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
PIEINNCF_02118	1.07e-207	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PIEINNCF_02119	7.43e-144	-	-	-	I	-	-	-	ABC-2 family transporter protein
PIEINNCF_02120	6.89e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
PIEINNCF_02121	8.73e-259	ald1	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
PIEINNCF_02122	1.06e-238	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PIEINNCF_02123	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
PIEINNCF_02124	3.4e-82	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
PIEINNCF_02125	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PIEINNCF_02126	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
PIEINNCF_02127	5.92e-314	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
PIEINNCF_02128	2.36e-125	-	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Bacterial regulatory proteins, tetR family
PIEINNCF_02129	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIEINNCF_02130	1.6e-286	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIEINNCF_02131	5.82e-95	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIEINNCF_02132	4.16e-199	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PIEINNCF_02133	0.0	msbA9	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PIEINNCF_02134	0.0	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PIEINNCF_02135	1.5e-96	-	-	-	S	-	-	-	NusG domain II
PIEINNCF_02136	6.72e-209	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
PIEINNCF_02137	7.99e-182	-	-	-	-	-	-	-	-
PIEINNCF_02138	5.1e-279	-	-	-	S	-	-	-	Membrane
PIEINNCF_02139	1.12e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
PIEINNCF_02140	6.43e-66	-	-	-	-	-	-	-	-
PIEINNCF_02141	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PIEINNCF_02142	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PIEINNCF_02143	2.5e-233	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
PIEINNCF_02144	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
PIEINNCF_02146	1.36e-302	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
PIEINNCF_02147	1.71e-241	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PIEINNCF_02148	6.98e-53	-	-	-	-	-	-	-	-
PIEINNCF_02149	4.1e-111	-	-	-	-	-	-	-	-
PIEINNCF_02150	6.71e-34	-	-	-	-	-	-	-	-
PIEINNCF_02151	4.72e-211	-	-	-	EG	-	-	-	EamA-like transporter family
PIEINNCF_02152	3.45e-144	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PIEINNCF_02153	9.59e-101	usp5	-	-	T	-	-	-	universal stress protein
PIEINNCF_02154	3.25e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
PIEINNCF_02155	1.29e-186	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PIEINNCF_02156	8.75e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
PIEINNCF_02157	1.54e-84	-	-	-	-	-	-	-	-
PIEINNCF_02158	1.41e-303	-	-	-	L	ko:K07485	-	ko00000	Transposase
PIEINNCF_02159	7.09e-113	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
PIEINNCF_02160	5.77e-93	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PIEINNCF_02161	2.13e-106	-	-	-	C	-	-	-	Flavodoxin
PIEINNCF_02162	1.05e-250	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PIEINNCF_02163	1.31e-146	-	-	-	GM	-	-	-	NmrA-like family
PIEINNCF_02164	2.92e-17	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PIEINNCF_02166	3.8e-130	-	-	-	Q	-	-	-	methyltransferase
PIEINNCF_02167	3.14e-142	-	-	-	T	-	-	-	Sh3 type 3 domain protein
PIEINNCF_02168	6.46e-150	-	-	-	F	-	-	-	glutamine amidotransferase
PIEINNCF_02169	4.29e-173	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
PIEINNCF_02170	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
PIEINNCF_02171	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PIEINNCF_02172	8.38e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PIEINNCF_02173	1.95e-127	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
PIEINNCF_02174	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PIEINNCF_02175	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PIEINNCF_02176	0.0	ydaO	-	-	E	-	-	-	amino acid
PIEINNCF_02177	5.32e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
PIEINNCF_02178	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PIEINNCF_02179	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PIEINNCF_02180	1.01e-141	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PIEINNCF_02181	5.83e-251	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PIEINNCF_02182	2.43e-222	-	-	-	-	-	-	-	-
PIEINNCF_02183	5.93e-204	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIEINNCF_02184	4.97e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
PIEINNCF_02185	1.1e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PIEINNCF_02186	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
PIEINNCF_02187	3.12e-68	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PIEINNCF_02188	5.99e-243	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PIEINNCF_02189	4.89e-129	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
PIEINNCF_02190	3.14e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
PIEINNCF_02191	1.7e-95	-	-	-	-	-	-	-	-
PIEINNCF_02192	6.94e-117	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
PIEINNCF_02193	6.13e-232	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
PIEINNCF_02194	3.86e-185	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
PIEINNCF_02195	4.28e-192	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PIEINNCF_02196	7.92e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
PIEINNCF_02197	2.28e-223	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PIEINNCF_02198	1.14e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
PIEINNCF_02199	7.2e-151	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PIEINNCF_02200	2.95e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
PIEINNCF_02201	1.26e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PIEINNCF_02202	5.75e-48	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PIEINNCF_02203	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIEINNCF_02204	4.38e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PIEINNCF_02205	9.05e-67	-	-	-	-	-	-	-	-
PIEINNCF_02206	2.44e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
PIEINNCF_02207	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PIEINNCF_02208	3.3e-59	-	-	-	-	-	-	-	-
PIEINNCF_02209	1.49e-225	ccpB	-	-	K	-	-	-	lacI family
PIEINNCF_02210	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PIEINNCF_02211	2.41e-205	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PIEINNCF_02212	1.37e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PIEINNCF_02213	7.23e-108	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PIEINNCF_02214	1.92e-283	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PIEINNCF_02215	1.73e-199	-	-	-	K	-	-	-	acetyltransferase
PIEINNCF_02216	3.45e-87	-	-	-	-	-	-	-	-
PIEINNCF_02217	1.19e-277	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
PIEINNCF_02218	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PIEINNCF_02219	1.89e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PIEINNCF_02220	6.87e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PIEINNCF_02221	1.82e-308	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
PIEINNCF_02222	4.76e-294	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
PIEINNCF_02223	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
PIEINNCF_02224	1.42e-85	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
PIEINNCF_02225	9.15e-122	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
PIEINNCF_02226	7.87e-125	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
PIEINNCF_02227	1.76e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
PIEINNCF_02228	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
PIEINNCF_02229	3.77e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
PIEINNCF_02230	4.04e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PIEINNCF_02231	2.29e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PIEINNCF_02232	2.09e-30	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PIEINNCF_02233	4.4e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PIEINNCF_02234	2.65e-219	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
PIEINNCF_02235	1.11e-212	menA	2.5.1.74	-	M	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
PIEINNCF_02236	1.27e-251	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PIEINNCF_02237	1.38e-186	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
PIEINNCF_02238	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PIEINNCF_02239	2.76e-104	-	-	-	S	-	-	-	NusG domain II
PIEINNCF_02240	1.03e-127	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
PIEINNCF_02241	3.02e-228	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PIEINNCF_02243	2.69e-157	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
PIEINNCF_02244	5.17e-249	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
PIEINNCF_02246	2.05e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
PIEINNCF_02247	3.14e-181	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIEINNCF_02248	4.83e-98	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PIEINNCF_02249	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PIEINNCF_02250	4.07e-272	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
PIEINNCF_02251	3.35e-34	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
PIEINNCF_02252	1.08e-138	-	-	-	-	-	-	-	-
PIEINNCF_02254	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PIEINNCF_02255	1.01e-149	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PIEINNCF_02256	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_02257	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_02258	3.34e-68	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PIEINNCF_02259	8.66e-152	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PIEINNCF_02260	1.42e-181	-	-	-	K	-	-	-	SIS domain
PIEINNCF_02261	2.26e-146	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
PIEINNCF_02262	6.51e-225	-	-	-	S	-	-	-	Membrane
PIEINNCF_02263	5.31e-82	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
PIEINNCF_02264	1.16e-302	-	-	-	L	ko:K07485	-	ko00000	Transposase
PIEINNCF_02265	1.93e-285	inlJ	-	-	M	-	-	-	MucBP domain
PIEINNCF_02266	5.49e-261	yacL	-	-	S	-	-	-	domain protein
PIEINNCF_02267	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PIEINNCF_02268	4.85e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
PIEINNCF_02269	1.22e-67	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
PIEINNCF_02270	2.42e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
PIEINNCF_02271	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PIEINNCF_02272	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PIEINNCF_02273	4.53e-254	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
PIEINNCF_02274	3.02e-276	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PIEINNCF_02275	1.17e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PIEINNCF_02276	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PIEINNCF_02277	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
PIEINNCF_02278	8.84e-120	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
PIEINNCF_02279	1.19e-158	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PIEINNCF_02281	1.92e-262	-	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PIEINNCF_02282	5.25e-61	-	-	-	-	-	-	-	-
PIEINNCF_02283	2.75e-175	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PIEINNCF_02284	1.31e-71	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PIEINNCF_02285	1.59e-28	yhjA	-	-	K	-	-	-	CsbD-like
PIEINNCF_02287	1.5e-44	-	-	-	-	-	-	-	-
PIEINNCF_02288	5.02e-52	-	-	-	-	-	-	-	-
PIEINNCF_02289	8.53e-287	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PIEINNCF_02290	3.14e-277	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PIEINNCF_02291	9e-190	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PIEINNCF_02293	2.57e-55	-	-	-	-	-	-	-	-
PIEINNCF_02294	2.79e-295	-	-	-	S	-	-	-	Membrane
PIEINNCF_02295	9e-189	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
PIEINNCF_02296	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
PIEINNCF_02297	1.01e-307	-	-	-	-	-	-	-	-
PIEINNCF_02298	0.0	-	-	-	M	-	-	-	domain protein
PIEINNCF_02299	3.13e-133	-	-	-	-	-	-	-	-
PIEINNCF_02300	1.09e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
PIEINNCF_02301	9.85e-263	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
PIEINNCF_02302	1.45e-143	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIEINNCF_02303	2.8e-70	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
PIEINNCF_02304	1.93e-80	-	-	-	-	-	-	-	-
PIEINNCF_02305	7.04e-175	-	-	-	-	-	-	-	-
PIEINNCF_02306	6.45e-59	-	-	-	S	-	-	-	Enterocin A Immunity
PIEINNCF_02307	9.06e-60	-	-	-	S	-	-	-	Enterocin A Immunity
PIEINNCF_02308	8.52e-60	spiA	-	-	K	-	-	-	TRANSCRIPTIONal
PIEINNCF_02309	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
PIEINNCF_02311	5.75e-72	-	-	-	-	-	-	-	-
PIEINNCF_02312	3.97e-310	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
PIEINNCF_02313	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PIEINNCF_02314	7.46e-144	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PIEINNCF_02316	1.44e-23	comD	2.7.13.3	-	T	ko:K07706,ko:K12294	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
PIEINNCF_02317	1.35e-175	-	2.7.13.3	-	T	ko:K02476,ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
PIEINNCF_02318	6.56e-183	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PIEINNCF_02320	1.62e-12	-	-	-	-	-	-	-	-
PIEINNCF_02324	2.7e-119	-	-	-	S	-	-	-	CAAX protease self-immunity
PIEINNCF_02325	2.14e-39	-	-	-	S	-	-	-	CAAX protease self-immunity
PIEINNCF_02327	1.11e-300	-	-	-	L	ko:K07485	-	ko00000	Transposase
PIEINNCF_02328	7.29e-25	-	-	-	-	-	-	-	-
PIEINNCF_02329	3.08e-05	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
PIEINNCF_02331	1.67e-72	-	-	-	S	-	-	-	Enterocin A Immunity
PIEINNCF_02332	3.07e-135	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
PIEINNCF_02336	1.45e-231	ydhF	-	-	S	-	-	-	Aldo keto reductase
PIEINNCF_02337	5.81e-165	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PIEINNCF_02338	2.12e-273	yqiG	-	-	C	-	-	-	Oxidoreductase
PIEINNCF_02339	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PIEINNCF_02340	2.2e-173	-	-	-	-	-	-	-	-
PIEINNCF_02341	6.42e-28	-	-	-	-	-	-	-	-
PIEINNCF_02342	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PIEINNCF_02343	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PIEINNCF_02344	9.77e-74	-	-	-	-	-	-	-	-
PIEINNCF_02345	2.97e-304	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PIEINNCF_02346	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
PIEINNCF_02347	8.86e-35	-	-	-	-	-	-	-	-
PIEINNCF_02348	9.05e-144	-	-	-	P	-	-	-	Cation efflux family
PIEINNCF_02349	1.23e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
PIEINNCF_02350	9.35e-226	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PIEINNCF_02351	5.89e-185	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
PIEINNCF_02352	3.38e-170	-	3.6.3.35	-	P	ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PIEINNCF_02353	0.0	aldA	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
PIEINNCF_02354	8.32e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIEINNCF_02355	6.75e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PIEINNCF_02356	2.83e-152	-	-	-	GM	-	-	-	NmrA-like family
PIEINNCF_02357	3.3e-145	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
PIEINNCF_02358	1.17e-100	-	-	-	-	-	-	-	-
PIEINNCF_02359	0.0	-	-	-	M	-	-	-	domain protein
PIEINNCF_02360	5.58e-166	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PIEINNCF_02361	5.64e-32	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PIEINNCF_02362	2.1e-27	-	-	-	-	-	-	-	-
PIEINNCF_02363	5.63e-97	-	-	-	-	-	-	-	-
PIEINNCF_02366	2.06e-67	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIEINNCF_02367	6.2e-89	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIEINNCF_02369	2.35e-47	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	phosphopyruvate hydratase activity
PIEINNCF_02370	1.99e-212	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
PIEINNCF_02371	8.64e-178	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PIEINNCF_02372	1e-173	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIEINNCF_02373	3.27e-187	ptxC	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIEINNCF_02374	1.48e-223	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
PIEINNCF_02375	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
PIEINNCF_02376	1.25e-159	-	-	-	I	-	-	-	Acyltransferase family
PIEINNCF_02377	2.43e-119	-	-	-	I	-	-	-	Acyltransferase family
PIEINNCF_02378	1.17e-154	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
PIEINNCF_02379	8.04e-190	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIEINNCF_02380	2.89e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
PIEINNCF_02381	6.18e-134	-	-	-	-	-	-	-	-
PIEINNCF_02382	6.17e-73	-	-	-	-	-	-	-	-
PIEINNCF_02383	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PIEINNCF_02384	2.98e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PIEINNCF_02385	3.44e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIEINNCF_02386	1.06e-237	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PIEINNCF_02387	1.01e-161	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PIEINNCF_02388	1.5e-44	-	-	-	-	-	-	-	-
PIEINNCF_02389	2.55e-168	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
PIEINNCF_02390	1.39e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PIEINNCF_02391	1.13e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIEINNCF_02392	1.92e-202	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIEINNCF_02393	1.15e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIEINNCF_02394	7.11e-151	-	-	-	-	-	-	-	-
PIEINNCF_02395	9.07e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PIEINNCF_02396	1.26e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIEINNCF_02397	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PIEINNCF_02398	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PIEINNCF_02399	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
PIEINNCF_02400	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PIEINNCF_02401	1.29e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PIEINNCF_02402	1.16e-302	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PIEINNCF_02403	4.07e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PIEINNCF_02404	2.6e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
PIEINNCF_02405	5.74e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PIEINNCF_02406	1.62e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PIEINNCF_02407	2.61e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PIEINNCF_02408	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PIEINNCF_02409	8.67e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PIEINNCF_02410	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PIEINNCF_02411	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PIEINNCF_02412	5.93e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PIEINNCF_02413	3.55e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PIEINNCF_02414	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PIEINNCF_02415	6.88e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PIEINNCF_02416	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PIEINNCF_02417	5.26e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PIEINNCF_02418	7.23e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PIEINNCF_02419	1.02e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PIEINNCF_02420	1.98e-140	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PIEINNCF_02421	4.01e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PIEINNCF_02422	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PIEINNCF_02423	2.35e-86	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
PIEINNCF_02424	4.81e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
PIEINNCF_02425	1.44e-256	-	-	-	K	-	-	-	WYL domain
PIEINNCF_02426	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PIEINNCF_02427	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PIEINNCF_02428	1.11e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PIEINNCF_02429	1.36e-230	-	-	-	M	-	-	-	domain protein
PIEINNCF_02430	0.0	-	-	-	M	-	-	-	domain protein
PIEINNCF_02431	3.63e-47	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
PIEINNCF_02432	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIEINNCF_02433	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIEINNCF_02434	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PIEINNCF_02435	4.32e-105	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
PIEINNCF_02445	5.19e-90	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
PIEINNCF_02448	1.45e-46	-	-	-	-	-	-	-	-
PIEINNCF_02449	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PIEINNCF_02450	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PIEINNCF_02451	5.11e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PIEINNCF_02452	1.77e-207	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PIEINNCF_02453	3.76e-240	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
PIEINNCF_02454	2.77e-249	-	-	-	S	-	-	-	Protein of unknown function C-terminal (DUF3324)
PIEINNCF_02455	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
PIEINNCF_02456	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PIEINNCF_02457	1.14e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PIEINNCF_02458	4.25e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PIEINNCF_02459	1.17e-105	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
PIEINNCF_02460	4.15e-86	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
PIEINNCF_02461	1.99e-53	yabO	-	-	J	-	-	-	S4 domain protein
PIEINNCF_02462	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PIEINNCF_02463	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PIEINNCF_02464	8.63e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PIEINNCF_02466	5.04e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PIEINNCF_02467	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PIEINNCF_02468	1.34e-154	-	-	-	S	-	-	-	(CBS) domain
PIEINNCF_02469	1.19e-168	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PIEINNCF_02470	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PIEINNCF_02471	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
PIEINNCF_02472	1.63e-111	queT	-	-	S	-	-	-	QueT transporter
PIEINNCF_02473	5.68e-83	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
PIEINNCF_02474	4.66e-44	-	-	-	-	-	-	-	-
PIEINNCF_02475	1.09e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PIEINNCF_02476	2.63e-82	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PIEINNCF_02477	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PIEINNCF_02479	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PIEINNCF_02480	1.7e-187	-	-	-	-	-	-	-	-
PIEINNCF_02481	4.35e-159	-	-	-	S	-	-	-	Tetratricopeptide repeat
PIEINNCF_02482	2.61e-163	-	-	-	-	-	-	-	-
PIEINNCF_02483	2.29e-87	-	-	-	-	-	-	-	-
PIEINNCF_02484	2.28e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PIEINNCF_02485	1.11e-298	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PIEINNCF_02486	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PIEINNCF_02487	3.42e-202	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PIEINNCF_02489	1.15e-111	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PIEINNCF_02490	3.48e-103	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
PIEINNCF_02491	4.01e-200	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
PIEINNCF_02492	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
PIEINNCF_02493	1.16e-102	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PIEINNCF_02494	3.04e-237	-	-	-	S	-	-	-	DUF218 domain
PIEINNCF_02495	1.31e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PIEINNCF_02496	1.11e-300	-	-	-	L	ko:K07485	-	ko00000	Transposase
PIEINNCF_02497	1.95e-104	-	-	-	E	-	-	-	glutamate:sodium symporter activity
PIEINNCF_02498	8.92e-73	nudA	-	-	S	-	-	-	ASCH
PIEINNCF_02499	2.2e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIEINNCF_02500	1.34e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PIEINNCF_02501	3.6e-286	ysaA	-	-	V	-	-	-	RDD family
PIEINNCF_02502	8.33e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
PIEINNCF_02503	1.29e-154	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_02504	2.4e-157	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
PIEINNCF_02505	1.99e-205	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
PIEINNCF_02506	2.7e-231	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PIEINNCF_02507	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
PIEINNCF_02508	6.82e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PIEINNCF_02509	6.78e-130	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PIEINNCF_02510	9.1e-190	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
PIEINNCF_02511	2.57e-104	manR	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
PIEINNCF_02512	1.35e-239	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
PIEINNCF_02513	1.22e-220	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
PIEINNCF_02514	2.78e-158	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PIEINNCF_02515	1.01e-199	-	-	-	T	-	-	-	GHKL domain
PIEINNCF_02516	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PIEINNCF_02517	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PIEINNCF_02518	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PIEINNCF_02519	5.84e-223	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PIEINNCF_02520	1.46e-196	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
PIEINNCF_02521	1.09e-118	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PIEINNCF_02522	3.11e-218	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PIEINNCF_02523	6.18e-137	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PIEINNCF_02524	1.34e-163	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
PIEINNCF_02525	6.41e-24	-	-	-	-	-	-	-	-
PIEINNCF_02526	5.59e-220	-	-	-	-	-	-	-	-
PIEINNCF_02527	5.33e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
PIEINNCF_02528	8.46e-51	-	-	-	-	-	-	-	-
PIEINNCF_02529	5.77e-204	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
PIEINNCF_02530	2.57e-223	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PIEINNCF_02531	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PIEINNCF_02532	2.38e-176	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PIEINNCF_02533	2.76e-149	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PIEINNCF_02534	3.37e-222	ydhF	-	-	S	-	-	-	Aldo keto reductase
PIEINNCF_02535	9.85e-197	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
PIEINNCF_02536	2.27e-119	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
PIEINNCF_02537	7.93e-306	dinF	-	-	V	-	-	-	MatE
PIEINNCF_02538	1.86e-151	-	-	-	S	ko:K06872	-	ko00000	TPM domain
PIEINNCF_02539	2.82e-133	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
PIEINNCF_02540	1.48e-246	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PIEINNCF_02541	7.61e-258	-	-	-	V	-	-	-	efflux transmembrane transporter activity
PIEINNCF_02542	2.81e-162	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
PIEINNCF_02543	7.68e-311	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
PIEINNCF_02544	6.07e-225	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_02545	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PIEINNCF_02547	0.0	-	-	-	L	-	-	-	DNA helicase
PIEINNCF_02548	1.62e-192	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
PIEINNCF_02549	6.52e-222	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
PIEINNCF_02550	2.13e-143	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PIEINNCF_02552	7.3e-149	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PIEINNCF_02553	1.84e-91	-	-	-	K	-	-	-	MarR family
PIEINNCF_02554	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
PIEINNCF_02555	6.25e-246	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
PIEINNCF_02556	2.79e-185	-	-	-	S	-	-	-	hydrolase
PIEINNCF_02557	4.04e-79	-	-	-	-	-	-	-	-
PIEINNCF_02558	1.99e-16	-	-	-	-	-	-	-	-
PIEINNCF_02559	1.34e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
PIEINNCF_02560	1.56e-161	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
PIEINNCF_02561	7.22e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PIEINNCF_02562	1.38e-117	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIEINNCF_02563	2.09e-211	-	-	-	K	-	-	-	LysR substrate binding domain
PIEINNCF_02564	4.96e-290	-	-	-	EK	-	-	-	Aminotransferase, class I
PIEINNCF_02565	1.97e-235	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PIEINNCF_02566	4.42e-154	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
PIEINNCF_02567	5.24e-116	-	-	-	-	-	-	-	-
PIEINNCF_02568	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PIEINNCF_02569	4.43e-222	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
PIEINNCF_02570	2.36e-167	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PIEINNCF_02571	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PIEINNCF_02572	2.94e-192	-	-	-	L	-	-	-	Uncharacterised protein family (UPF0236)
PIEINNCF_02573	2.22e-174	-	-	-	K	-	-	-	UTRA domain
PIEINNCF_02574	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
PIEINNCF_02575	2.73e-213	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PIEINNCF_02576	1.89e-166	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PIEINNCF_02577	2.84e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PIEINNCF_02578	3.09e-63	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
PIEINNCF_02579	5.16e-66	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PIEINNCF_02580	0.0	bgl	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIEINNCF_02581	1.05e-195	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
PIEINNCF_02582	9.64e-317	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
PIEINNCF_02583	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
PIEINNCF_02584	1.54e-307	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEINNCF_02585	4.48e-172	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
PIEINNCF_02587	1.51e-175	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
PIEINNCF_02589	0.0	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PIEINNCF_02590	5.11e-67	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PIEINNCF_02591	1.49e-107	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PIEINNCF_02592	5.43e-185	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
PIEINNCF_02593	3.2e-206	-	-	-	J	-	-	-	Methyltransferase domain
PIEINNCF_02594	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PIEINNCF_02597	0.0	-	-	-	M	-	-	-	Right handed beta helix region
PIEINNCF_02598	9.35e-97	-	-	-	-	-	-	-	-
PIEINNCF_02599	0.0	-	-	-	M	-	-	-	Heparinase II/III N-terminus
PIEINNCF_02601	6.62e-105	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PIEINNCF_02602	8.63e-185	agaD	-	-	G	ko:K02747	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PIEINNCF_02603	7.99e-185	-	-	-	G	ko:K02746	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PIEINNCF_02604	1.72e-114	-	-	-	G	ko:K02745	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PIEINNCF_02605	2.47e-295	ugl	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
PIEINNCF_02606	9.16e-203	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PIEINNCF_02607	3.14e-179	-	-	-	K	-	-	-	Bacterial transcriptional regulator
PIEINNCF_02608	5.33e-209	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PIEINNCF_02609	6.38e-193	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIEINNCF_02610	2.82e-154	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
PIEINNCF_02611	8.25e-249	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
PIEINNCF_02612	4.7e-156	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
PIEINNCF_02613	7.16e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PIEINNCF_02614	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PIEINNCF_02615	9.03e-37	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
PIEINNCF_02616	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_02617	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_02619	7.04e-121	-	-	-	K	-	-	-	Helix-turn-helix domain
PIEINNCF_02620	7.64e-155	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PIEINNCF_02621	1.36e-91	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PIEINNCF_02622	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIEINNCF_02623	2.92e-192	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIEINNCF_02624	7.5e-210	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
PIEINNCF_02625	7.33e-271	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
PIEINNCF_02626	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PIEINNCF_02627	1.89e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
PIEINNCF_02628	1.1e-173	-	-	-	F	-	-	-	NUDIX domain
PIEINNCF_02629	4.85e-186	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
PIEINNCF_02630	1.12e-245	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
PIEINNCF_02631	1.04e-247	-	-	-	V	-	-	-	Beta-lactamase
PIEINNCF_02632	1.43e-197	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PIEINNCF_02633	3.72e-210	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PIEINNCF_02634	1.67e-105	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PIEINNCF_02635	1.56e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PIEINNCF_02636	8.76e-177	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PIEINNCF_02637	3.04e-259	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
PIEINNCF_02638	7.62e-219	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
PIEINNCF_02639	1.53e-172	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
PIEINNCF_02640	8.82e-68	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
PIEINNCF_02641	3.68e-172	-	-	-	S	-	-	-	-acetyltransferase
PIEINNCF_02642	2.27e-119	yfbM	-	-	K	-	-	-	FR47-like protein
PIEINNCF_02643	1.15e-120	-	-	-	E	-	-	-	HAD-hyrolase-like
PIEINNCF_02644	6.05e-229	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
PIEINNCF_02645	3.52e-174	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PIEINNCF_02646	2.72e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIEINNCF_02647	6.19e-105	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PIEINNCF_02648	3.04e-55	-	-	-	K	ko:K03830	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PIEINNCF_02649	1.43e-84	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PIEINNCF_02650	2.19e-30	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
PIEINNCF_02651	2.76e-78	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
PIEINNCF_02653	4.42e-34	-	-	-	-	-	-	-	-
PIEINNCF_02654	1.53e-99	-	3.1.1.85	-	S	ko:K02170,ko:K07002	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	thiolester hydrolase activity
PIEINNCF_02655	2.52e-29	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_02656	7.76e-53	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_02657	4.74e-118	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
PIEINNCF_02658	6.01e-103	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PIEINNCF_02659	5.21e-116	-	-	-	G	-	-	-	PTS system sorbose-specific iic component
PIEINNCF_02660	6.14e-134	-	-	-	G	ko:K19509	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PIEINNCF_02661	8.4e-297	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
PIEINNCF_02663	6.87e-114	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PIEINNCF_02664	3.62e-32	-	-	-	-	-	-	-	-
PIEINNCF_02665	1.19e-95	-	-	-	S	ko:K09702	-	ko00000	Protein of unknown function (DUF1349)
PIEINNCF_02666	9.05e-18	-	-	-	-	-	-	-	-
PIEINNCF_02667	4.55e-26	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
PIEINNCF_02669	1.09e-16	-	-	-	S	-	-	-	Mor transcription activator family
PIEINNCF_02672	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PIEINNCF_02673	6.32e-253	ysdE	-	-	P	-	-	-	Citrate transporter
PIEINNCF_02674	3.05e-91	-	-	-	-	-	-	-	-
PIEINNCF_02675	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
PIEINNCF_02676	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PIEINNCF_02677	2.76e-132	-	-	-	-	-	-	-	-
PIEINNCF_02678	0.0	cadA	-	-	P	-	-	-	P-type ATPase
PIEINNCF_02679	1.8e-99	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PIEINNCF_02680	2.35e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PIEINNCF_02681	1.7e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
PIEINNCF_02683	4.32e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
PIEINNCF_02684	1.05e-182	yycI	-	-	S	-	-	-	YycH protein
PIEINNCF_02685	0.0	yycH	-	-	S	-	-	-	YycH protein
PIEINNCF_02686	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PIEINNCF_02687	3.03e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PIEINNCF_02688	4.31e-157	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
PIEINNCF_02689	0.0	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PIEINNCF_02690	1.63e-298	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
PIEINNCF_02691	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
PIEINNCF_02692	6.51e-271	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
PIEINNCF_02693	9.09e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
PIEINNCF_02694	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEINNCF_02695	1.97e-168	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
PIEINNCF_02696	3.39e-67	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PIEINNCF_02697	8.36e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
PIEINNCF_02698	3.03e-139	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PIEINNCF_02699	3.71e-110	-	-	-	F	-	-	-	NUDIX domain
PIEINNCF_02700	2.15e-116	-	-	-	S	-	-	-	AAA domain
PIEINNCF_02701	3.32e-148	ycaC	-	-	Q	-	-	-	Isochorismatase family
PIEINNCF_02702	8.72e-55	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PIEINNCF_02703	6.89e-107	-	-	-	L	-	-	-	Transposase DDE domain
PIEINNCF_02704	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PIEINNCF_02705	2.72e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PIEINNCF_02706	1.96e-271	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
PIEINNCF_02707	1.22e-219	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
PIEINNCF_02708	1.08e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
PIEINNCF_02709	1.3e-211	manN	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
PIEINNCF_02710	3.16e-171	manM	-	-	G	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
PIEINNCF_02711	1.44e-230	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PIEINNCF_02712	4.27e-48	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
PIEINNCF_02713	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PIEINNCF_02714	2.31e-105	-	-	-	L	-	-	-	Transposase DDE domain
PIEINNCF_02715	0.0	cadA	-	-	P	-	-	-	P-type ATPase
PIEINNCF_02716	2.25e-38	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PIEINNCF_02717	1.46e-103	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PIEINNCF_02718	2.7e-162	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
PIEINNCF_02719	2.26e-27	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PIEINNCF_02720	4.3e-36	-	-	-	-	-	-	-	-
PIEINNCF_02721	6.37e-82	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
PIEINNCF_02722	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PIEINNCF_02723	8.51e-80	arlR	-	-	K	ko:K18941	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
PIEINNCF_02724	5.97e-214	kdpD	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PIEINNCF_02725	6.77e-26	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PIEINNCF_02726	1.32e-29	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit
PIEINNCF_02727	1.23e-313	kdpB	-	-	P	-	-	-	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PIEINNCF_02728	6.07e-210	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PIEINNCF_02730	1.45e-296	-	-	-	L	ko:K07485	-	ko00000	Transposase
PIEINNCF_02731	9.32e-140	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
PIEINNCF_02732	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_02733	8.71e-59	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_02734	7.95e-280	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
PIEINNCF_02735	1.87e-88	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
PIEINNCF_02737	1.64e-116	-	-	-	-	-	-	-	-
PIEINNCF_02738	1.56e-60	-	-	-	L	-	-	-	BRCA1 C Terminus (BRCT) domain
PIEINNCF_02739	7.73e-147	-	-	-	L	-	-	-	Resolvase, N terminal domain
PIEINNCF_02740	6.62e-66	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
PIEINNCF_02741	4.96e-44	-	-	-	L	-	-	-	RelB antitoxin
PIEINNCF_02742	7.21e-08	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
PIEINNCF_02743	2.81e-106	-	-	-	L	-	-	-	Transposase DDE domain
PIEINNCF_02744	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PIEINNCF_02745	1.22e-158	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
PIEINNCF_02746	2.98e-71	-	-	-	L	-	-	-	Transposase DDE domain
PIEINNCF_02747	1.22e-219	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
PIEINNCF_02748	1.08e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
PIEINNCF_02749	1.3e-211	manN	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
PIEINNCF_02750	3.16e-171	manM	-	-	G	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
PIEINNCF_02751	1.44e-230	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PIEINNCF_02752	9.77e-279	-	-	-	EGP	-	-	-	Major facilitator Superfamily
PIEINNCF_02753	1.03e-242	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
PIEINNCF_02754	8.33e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIEINNCF_02755	3.42e-201	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
PIEINNCF_02757	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIEINNCF_02758	3.81e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_02759	4.51e-41	-	-	-	-	-	-	-	-
PIEINNCF_02760	1.21e-304	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIEINNCF_02761	1.82e-164	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
PIEINNCF_02762	5.96e-53	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PIEINNCF_02763	8.12e-69	-	-	-	-	-	-	-	-
PIEINNCF_02764	8.68e-106	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
PIEINNCF_02765	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
PIEINNCF_02766	3.69e-184	-	-	-	S	-	-	-	AAA ATPase domain
PIEINNCF_02767	7.92e-215	-	-	-	G	-	-	-	Phosphotransferase enzyme family
PIEINNCF_02768	3.31e-302	-	-	-	L	ko:K07485	-	ko00000	Transposase
PIEINNCF_02769	1.09e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIEINNCF_02770	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIEINNCF_02771	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIEINNCF_02772	9.37e-129	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PIEINNCF_02773	7.75e-138	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
PIEINNCF_02774	9.04e-183	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
PIEINNCF_02775	5.27e-236	-	-	-	S	-	-	-	Protein of unknown function DUF58
PIEINNCF_02776	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
PIEINNCF_02777	1.42e-271	-	-	-	M	-	-	-	Glycosyl transferases group 1
PIEINNCF_02778	1.34e-126	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
PIEINNCF_02779	1.57e-188	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
PIEINNCF_02780	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
PIEINNCF_02781	1e-147	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
PIEINNCF_02782	3.05e-22	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
PIEINNCF_02783	6.31e-273	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
PIEINNCF_02784	5.39e-292	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
PIEINNCF_02785	0.0	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
PIEINNCF_02786	1.55e-157	malR	-	-	KT	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
PIEINNCF_02787	1.28e-193	-	-	-	I	-	-	-	NAD binding domain of 6-phosphogluconate dehydrogenase
PIEINNCF_02788	3.89e-117	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
PIEINNCF_02789	1.85e-56	-	-	-	-	-	-	-	-
PIEINNCF_02790	3.55e-281	yagE	-	-	E	-	-	-	Amino acid permease
PIEINNCF_02791	5.79e-218	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PIEINNCF_02793	1.87e-217	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIEINNCF_02794	7.75e-232	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
PIEINNCF_02795	5.29e-239	lipA	-	-	I	-	-	-	Carboxylesterase family
PIEINNCF_02796	1.38e-274	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
PIEINNCF_02797	9.2e-101	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIEINNCF_02798	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
PIEINNCF_02799	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PIEINNCF_02800	2.09e-169	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PIEINNCF_02801	3.86e-192	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PIEINNCF_02802	5.93e-59	-	-	-	-	-	-	-	-
PIEINNCF_02803	6.72e-19	-	-	-	-	-	-	-	-
PIEINNCF_02804	6.14e-238	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PIEINNCF_02805	2.9e-160	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PIEINNCF_02806	3.59e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
PIEINNCF_02807	4.89e-113	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
PIEINNCF_02808	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_02809	5.05e-58	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_02810	3.15e-118	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
PIEINNCF_02811	5.05e-58	-	-	-	L	ko:K07483	-	ko00000	4.5 Transposon and IS
PIEINNCF_02812	3.44e-198	-	-	-	L	ko:K07497	-	ko00000	4.5 Transposon and IS
PIEINNCF_02813	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
PIEINNCF_02814	1.1e-255	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
PIEINNCF_02815	8.87e-288	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
PIEINNCF_02816	1.48e-104	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PIEINNCF_02817	3.8e-175	labL	-	-	S	-	-	-	Putative threonine/serine exporter
PIEINNCF_02818	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PIEINNCF_02819	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PIEINNCF_02820	1.42e-170	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
PIEINNCF_02821	4.53e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIEINNCF_02822	2.99e-77	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PIEINNCF_02823	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
PIEINNCF_02824	0.0	-	-	-	L	-	-	-	AlwI restriction endonuclease
PIEINNCF_02825	2.12e-222	dpnM	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
PIEINNCF_02826	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PIEINNCF_02827	4.34e-80	-	-	-	-	-	-	-	-
PIEINNCF_02828	8.4e-199	-	-	-	-	-	-	-	-
PIEINNCF_02829	3.49e-79	-	-	-	-	-	-	-	-
PIEINNCF_02830	0.0	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
PIEINNCF_02831	5.66e-106	-	-	-	-	-	-	-	-
PIEINNCF_02832	1.12e-82	-	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
PIEINNCF_02833	4.34e-118	-	-	-	-	-	-	-	-
PIEINNCF_02834	9.04e-278	-	-	-	M	-	-	-	CHAP domain
PIEINNCF_02835	0.0	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
PIEINNCF_02836	0.0	-	-	-	U	-	-	-	AAA-like domain
PIEINNCF_02837	1.9e-153	-	-	-	-	-	-	-	-
PIEINNCF_02838	1.27e-69	-	-	-	-	-	-	-	-
PIEINNCF_02839	1.55e-68	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
PIEINNCF_02840	1.18e-128	-	-	-	-	-	-	-	-
PIEINNCF_02841	4.98e-68	-	-	-	-	-	-	-	-
PIEINNCF_02842	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
PIEINNCF_02843	9.79e-37	-	-	-	-	-	-	-	-
PIEINNCF_02844	1.03e-55	-	-	-	-	-	-	-	-
PIEINNCF_02845	5.68e-163	-	-	-	S	-	-	-	protein conserved in bacteria
PIEINNCF_02846	5.93e-37	-	-	-	-	-	-	-	-
PIEINNCF_02847	2.83e-58	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
PIEINNCF_02848	7.67e-205	repA	-	-	S	-	-	-	Replication initiator protein A
PIEINNCF_02849	1.86e-48	-	-	-	-	-	-	-	-
PIEINNCF_02850	1.19e-190	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
PIEINNCF_02852	3.38e-76	-	-	-	J	-	-	-	tRNA cytidylyltransferase activity
PIEINNCF_02853	2.34e-128	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
PIEINNCF_02854	3.62e-57	-	-	-	S	-	-	-	FRG
PIEINNCF_02856	5.05e-314	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
PIEINNCF_02857	1.16e-72	-	-	-	-	-	-	-	-
PIEINNCF_02858	2.59e-84	-	-	-	-	-	-	-	-
PIEINNCF_02859	5.59e-273	-	-	-	S	-	-	-	Protein of unknown function DUF262
PIEINNCF_02860	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
PIEINNCF_02862	1.55e-19	-	-	-	-	-	-	-	-
PIEINNCF_02864	2.47e-105	-	-	-	L	-	-	-	Initiator Replication protein
PIEINNCF_02866	3.29e-98	-	-	-	V	-	-	-	HNH endonuclease
PIEINNCF_02869	6.89e-107	-	-	-	L	-	-	-	Transposase DDE domain
PIEINNCF_02870	1.51e-77	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
PIEINNCF_02871	1.43e-06	-	-	-	-	-	-	-	-