ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LNENKMEB_00001 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LNENKMEB_00004 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
LNENKMEB_00005 2.41e-135 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LNENKMEB_00006 7.58e-248 yaaN - - P - - - Belongs to the TelA family
LNENKMEB_00007 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
LNENKMEB_00008 7.75e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LNENKMEB_00009 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
LNENKMEB_00010 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
LNENKMEB_00011 3.29e-234 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LNENKMEB_00012 9e-189 yaaT - - S - - - stage 0 sporulation protein
LNENKMEB_00013 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
LNENKMEB_00014 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
LNENKMEB_00015 6.96e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
LNENKMEB_00016 2.85e-210 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LNENKMEB_00017 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
LNENKMEB_00018 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LNENKMEB_00019 4.31e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
LNENKMEB_00020 6.47e-268 yabE - - T - - - protein conserved in bacteria
LNENKMEB_00021 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LNENKMEB_00022 8.41e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LNENKMEB_00023 1.41e-209 yabG - - S ko:K06436 - ko00000 peptidase
LNENKMEB_00024 5.32e-53 veg - - S - - - protein conserved in bacteria
LNENKMEB_00025 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
LNENKMEB_00026 5.51e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LNENKMEB_00027 1.62e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LNENKMEB_00028 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
LNENKMEB_00029 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LNENKMEB_00030 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LNENKMEB_00031 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LNENKMEB_00032 6.18e-137 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LNENKMEB_00033 2.89e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LNENKMEB_00034 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
LNENKMEB_00035 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LNENKMEB_00036 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
LNENKMEB_00037 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LNENKMEB_00038 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LNENKMEB_00039 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LNENKMEB_00040 5.47e-66 yabP - - S - - - Sporulation protein YabP
LNENKMEB_00041 1.18e-134 yabQ - - S - - - spore cortex biosynthesis protein
LNENKMEB_00042 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LNENKMEB_00043 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LNENKMEB_00046 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
LNENKMEB_00047 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LNENKMEB_00048 3.16e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
LNENKMEB_00049 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LNENKMEB_00050 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
LNENKMEB_00051 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LNENKMEB_00052 8.14e-178 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LNENKMEB_00053 3.19e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LNENKMEB_00054 3.55e-201 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
LNENKMEB_00055 8.88e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LNENKMEB_00056 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LNENKMEB_00057 5.35e-139 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
LNENKMEB_00058 1.03e-208 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
LNENKMEB_00059 2.24e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LNENKMEB_00060 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LNENKMEB_00061 8.2e-118 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LNENKMEB_00062 6.1e-40 yazB - - K - - - transcriptional
LNENKMEB_00063 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LNENKMEB_00064 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LNENKMEB_00065 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LNENKMEB_00075 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LNENKMEB_00076 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
LNENKMEB_00077 1.14e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
LNENKMEB_00078 3.84e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LNENKMEB_00079 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
LNENKMEB_00080 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LNENKMEB_00081 3.12e-250 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LNENKMEB_00082 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
LNENKMEB_00083 1.23e-160 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LNENKMEB_00084 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LNENKMEB_00085 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LNENKMEB_00086 3.16e-151 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
LNENKMEB_00087 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LNENKMEB_00088 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LNENKMEB_00089 1.01e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LNENKMEB_00090 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
LNENKMEB_00091 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
LNENKMEB_00092 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LNENKMEB_00093 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LNENKMEB_00094 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LNENKMEB_00095 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LNENKMEB_00096 2.33e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LNENKMEB_00097 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LNENKMEB_00098 7.25e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LNENKMEB_00099 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LNENKMEB_00100 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LNENKMEB_00101 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
LNENKMEB_00102 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LNENKMEB_00103 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LNENKMEB_00104 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LNENKMEB_00105 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LNENKMEB_00106 8.14e-240 ybaC - - S - - - Alpha/beta hydrolase family
LNENKMEB_00107 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LNENKMEB_00108 3.57e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LNENKMEB_00109 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LNENKMEB_00110 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LNENKMEB_00111 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LNENKMEB_00112 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LNENKMEB_00113 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LNENKMEB_00114 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LNENKMEB_00115 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LNENKMEB_00116 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LNENKMEB_00117 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LNENKMEB_00118 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LNENKMEB_00119 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LNENKMEB_00120 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LNENKMEB_00121 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LNENKMEB_00122 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LNENKMEB_00123 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LNENKMEB_00124 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LNENKMEB_00125 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LNENKMEB_00126 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LNENKMEB_00127 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LNENKMEB_00128 7.75e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LNENKMEB_00129 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LNENKMEB_00130 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LNENKMEB_00131 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LNENKMEB_00132 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
LNENKMEB_00133 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LNENKMEB_00134 2.28e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LNENKMEB_00135 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LNENKMEB_00136 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LNENKMEB_00137 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LNENKMEB_00138 6.97e-190 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LNENKMEB_00139 2.77e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LNENKMEB_00140 8.74e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LNENKMEB_00141 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LNENKMEB_00142 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LNENKMEB_00143 2.06e-184 ybaJ - - Q - - - Methyltransferase domain
LNENKMEB_00144 1.56e-108 yizA - - S - - - Damage-inducible protein DinB
LNENKMEB_00145 1.08e-101 ybaK - - S - - - Protein of unknown function (DUF2521)
LNENKMEB_00146 1.98e-173 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LNENKMEB_00147 2.21e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LNENKMEB_00148 6.81e-103 gerD - - - ko:K06294 - ko00000 -
LNENKMEB_00149 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
LNENKMEB_00150 9.06e-183 pdaB - - G - - - Polysaccharide deacetylase
LNENKMEB_00151 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LNENKMEB_00157 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LNENKMEB_00158 6.41e-281 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
LNENKMEB_00159 1.27e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LNENKMEB_00160 3.68e-229 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
LNENKMEB_00161 9.77e-257 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
LNENKMEB_00162 1.11e-287 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LNENKMEB_00163 1.26e-221 ybaS - - S - - - Na -dependent transporter
LNENKMEB_00164 1.26e-148 ybbA - - S ko:K07017 - ko00000 Putative esterase
LNENKMEB_00165 3.37e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LNENKMEB_00166 4.24e-224 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LNENKMEB_00167 2.1e-220 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
LNENKMEB_00168 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
LNENKMEB_00169 7.8e-301 ybbC - - S - - - protein conserved in bacteria
LNENKMEB_00170 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
LNENKMEB_00171 1.18e-313 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
LNENKMEB_00172 3.54e-311 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LNENKMEB_00173 9.86e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LNENKMEB_00174 1.82e-112 ybbJ - - J - - - acetyltransferase
LNENKMEB_00175 1.93e-101 ybbK - - S - - - Protein of unknown function (DUF523)
LNENKMEB_00181 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LNENKMEB_00182 1.11e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LNENKMEB_00183 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LNENKMEB_00184 5.88e-290 ybbR - - S - - - protein conserved in bacteria
LNENKMEB_00185 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LNENKMEB_00186 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LNENKMEB_00187 5.87e-197 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LNENKMEB_00188 2.02e-138 - - - S - - - ABC-2 family transporter protein
LNENKMEB_00189 1.31e-125 ybdN - - - - - - -
LNENKMEB_00190 2.61e-166 ybdO - - S - - - Domain of unknown function (DUF4885)
LNENKMEB_00191 1.06e-197 dkgB - - S - - - Aldo/keto reductase family
LNENKMEB_00192 7.37e-136 yxaC - - M - - - effector of murein hydrolase
LNENKMEB_00193 2.29e-92 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LNENKMEB_00194 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LNENKMEB_00195 7.81e-118 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LNENKMEB_00196 5e-132 - - - T - - - Histidine kinase
LNENKMEB_00197 1.24e-104 - - - KT - - - helix_turn_helix, Lux Regulon
LNENKMEB_00198 9.14e-172 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_00199 4.3e-184 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LNENKMEB_00200 1.89e-154 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LNENKMEB_00201 1.62e-19 - - - - - - - -
LNENKMEB_00202 1.97e-73 - - - Q - - - Thioesterase domain
LNENKMEB_00203 0.0 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
LNENKMEB_00204 0.0 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
LNENKMEB_00205 1.92e-150 - 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 PFAM Acyl transferase
LNENKMEB_00206 0.0 - - - Q - - - Beta-ketoacyl synthase
LNENKMEB_00207 0.0 - - - Q - - - Polyketide synthase modules and related proteins
LNENKMEB_00208 1.45e-120 - - - Q - - - Flavin containing amine oxidoreductase
LNENKMEB_00209 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
LNENKMEB_00210 6.02e-51 - - - Q - - - Dimerisation domain
LNENKMEB_00211 3.52e-101 - - - S - - - Domain of unknown function (DUF4879)
LNENKMEB_00212 7.13e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
LNENKMEB_00213 7.51e-146 yqeB - - - - - - -
LNENKMEB_00214 7.84e-55 ybyB - - - - - - -
LNENKMEB_00215 0.0 ybeC - - E - - - amino acid
LNENKMEB_00216 5.43e-54 - - - M - - - PFAM Glycosyl transferase family 2
LNENKMEB_00217 4.35e-206 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
LNENKMEB_00218 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
LNENKMEB_00219 5.8e-23 - - - S - - - Protein of unknown function (DUF2651)
LNENKMEB_00220 6.74e-266 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
LNENKMEB_00222 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
LNENKMEB_00223 2.44e-45 - - - - - - - -
LNENKMEB_00224 1.69e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
LNENKMEB_00225 3.53e-254 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
LNENKMEB_00226 1.38e-272 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LNENKMEB_00227 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LNENKMEB_00228 4.98e-112 ybfM - - S - - - SNARE associated Golgi protein
LNENKMEB_00229 3.05e-194 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LNENKMEB_00230 1.5e-55 ybfN - - - - - - -
LNENKMEB_00231 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
LNENKMEB_00232 8.22e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LNENKMEB_00233 5.02e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LNENKMEB_00234 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LNENKMEB_00235 4.32e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
LNENKMEB_00236 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LNENKMEB_00237 1.11e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LNENKMEB_00238 2.65e-280 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_00239 5.81e-221 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
LNENKMEB_00240 6.9e-35 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
LNENKMEB_00241 2.59e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LNENKMEB_00242 1.15e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
LNENKMEB_00243 1.24e-234 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LNENKMEB_00244 9.37e-83 ydfP - - S ko:K15977 - ko00000 DoxX
LNENKMEB_00245 1.54e-73 ydfQ - - CO - - - Thioredoxin
LNENKMEB_00246 6.64e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
LNENKMEB_00247 1.05e-101 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
LNENKMEB_00248 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
LNENKMEB_00249 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LNENKMEB_00250 2.74e-157 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LNENKMEB_00251 5.93e-155 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LNENKMEB_00252 1.41e-265 ycbU - - E - - - Selenocysteine lyase
LNENKMEB_00253 1.61e-309 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
LNENKMEB_00254 2.19e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LNENKMEB_00255 3.55e-257 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LNENKMEB_00256 5.23e-144 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
LNENKMEB_00257 4.81e-252 yccF - - K ko:K07039 - ko00000 SEC-C motif
LNENKMEB_00258 1.87e-219 yccK - - C - - - Aldo keto reductase
LNENKMEB_00259 1.08e-224 ycdA - - S - - - Domain of unknown function (DUF5105)
LNENKMEB_00260 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LNENKMEB_00261 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LNENKMEB_00262 1.42e-118 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LNENKMEB_00263 2.35e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
LNENKMEB_00264 2.48e-178 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
LNENKMEB_00265 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LNENKMEB_00266 2.46e-212 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LNENKMEB_00267 1.4e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LNENKMEB_00268 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LNENKMEB_00269 6.94e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LNENKMEB_00270 1.16e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
LNENKMEB_00271 2.98e-135 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LNENKMEB_00272 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LNENKMEB_00273 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
LNENKMEB_00274 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
LNENKMEB_00275 3.34e-246 yceH - - P - - - Belongs to the TelA family
LNENKMEB_00276 1.28e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
LNENKMEB_00277 1.28e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
LNENKMEB_00278 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LNENKMEB_00279 9.95e-211 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LNENKMEB_00280 1.13e-270 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
LNENKMEB_00281 8.03e-294 ycgA - - S - - - Membrane
LNENKMEB_00282 5.15e-105 ycgB - - - - - - -
LNENKMEB_00283 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
LNENKMEB_00284 1.14e-228 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LNENKMEB_00285 0.0 mdr - - EGP - - - the major facilitator superfamily
LNENKMEB_00286 6.92e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
LNENKMEB_00287 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
LNENKMEB_00288 1.99e-190 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
LNENKMEB_00289 4.47e-312 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LNENKMEB_00290 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
LNENKMEB_00291 7.44e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LNENKMEB_00292 1.23e-151 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
LNENKMEB_00293 2.04e-66 - - - L - - - transposase activity
LNENKMEB_00294 6.96e-07 - - - S - - - Bacillus cereus group antimicrobial protein
LNENKMEB_00295 3.74e-138 tmrB - - S - - - AAA domain
LNENKMEB_00296 6.64e-189 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
LNENKMEB_00297 3.2e-302 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LNENKMEB_00298 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LNENKMEB_00299 2.41e-235 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
LNENKMEB_00300 8.73e-189 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
LNENKMEB_00301 5.55e-216 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LNENKMEB_00302 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LNENKMEB_00303 1.28e-310 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LNENKMEB_00304 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
LNENKMEB_00305 1.65e-242 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LNENKMEB_00306 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LNENKMEB_00307 5.95e-75 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
LNENKMEB_00308 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LNENKMEB_00309 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LNENKMEB_00310 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
LNENKMEB_00311 9.53e-284 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LNENKMEB_00312 1.31e-285 yciC - - S - - - GTPases (G3E family)
LNENKMEB_00313 2.06e-280 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LNENKMEB_00314 2.67e-96 yckC - - S - - - membrane
LNENKMEB_00315 1.92e-67 - - - S - - - Protein of unknown function (DUF2680)
LNENKMEB_00316 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LNENKMEB_00317 6.79e-91 nin - - S - - - Competence protein J (ComJ)
LNENKMEB_00318 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
LNENKMEB_00319 3.11e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
LNENKMEB_00320 1.1e-139 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
LNENKMEB_00321 4.1e-84 hxlR - - K - - - transcriptional
LNENKMEB_00322 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LNENKMEB_00323 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LNENKMEB_00324 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
LNENKMEB_00325 6.15e-180 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
LNENKMEB_00326 0.0 - - - E - - - Aminotransferase class I and II
LNENKMEB_00327 3.86e-84 - - - S - - - YcxB-like protein
LNENKMEB_00328 7.86e-217 ycxC - - EG - - - EamA-like transporter family
LNENKMEB_00329 1.04e-306 ycxD - - K - - - GntR family transcriptional regulator
LNENKMEB_00330 1.11e-168 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
LNENKMEB_00331 2.99e-142 yczE - - S ko:K07149 - ko00000 membrane
LNENKMEB_00332 2.78e-169 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LNENKMEB_00333 2.9e-152 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LNENKMEB_00334 1.89e-185 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LNENKMEB_00335 3.45e-205 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
LNENKMEB_00336 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LNENKMEB_00337 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LNENKMEB_00338 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
LNENKMEB_00339 1.01e-101 yclD - - - - - - -
LNENKMEB_00340 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
LNENKMEB_00341 0.0 yclG - - M - - - Pectate lyase superfamily protein
LNENKMEB_00343 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
LNENKMEB_00344 5.93e-302 gerKC - - S ko:K06297 - ko00000 spore germination
LNENKMEB_00345 9.23e-249 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
LNENKMEB_00346 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LNENKMEB_00347 3.64e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LNENKMEB_00348 1.56e-183 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LNENKMEB_00349 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LNENKMEB_00350 5.6e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_00351 5.04e-279 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
LNENKMEB_00352 9.28e-317 yxeQ - - S - - - MmgE/PrpD family
LNENKMEB_00353 2.12e-154 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LNENKMEB_00354 1.1e-312 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
LNENKMEB_00355 9.08e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LNENKMEB_00356 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
LNENKMEB_00357 5.98e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LNENKMEB_00359 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LNENKMEB_00360 7.78e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LNENKMEB_00361 1.64e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LNENKMEB_00362 4.63e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_00363 6.82e-224 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
LNENKMEB_00364 3.43e-314 ycnB - - EGP - - - the major facilitator superfamily
LNENKMEB_00365 1.05e-195 ycnC - - K - - - Transcriptional regulator
LNENKMEB_00366 1.38e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
LNENKMEB_00367 1.14e-58 ycnE - - S - - - Monooxygenase
LNENKMEB_00368 9.26e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LNENKMEB_00369 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LNENKMEB_00370 1.2e-284 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LNENKMEB_00371 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LNENKMEB_00372 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
LNENKMEB_00373 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LNENKMEB_00374 1.39e-129 ycnI - - S - - - protein conserved in bacteria
LNENKMEB_00375 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
LNENKMEB_00376 4.26e-138 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LNENKMEB_00377 9.6e-73 - - - - - - - -
LNENKMEB_00378 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
LNENKMEB_00379 5.84e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LNENKMEB_00380 1.41e-264 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
LNENKMEB_00381 8.28e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
LNENKMEB_00383 1.34e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LNENKMEB_00384 6.12e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
LNENKMEB_00385 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
LNENKMEB_00386 2.07e-193 ycsI - - S - - - Belongs to the D-glutamate cyclase family
LNENKMEB_00387 9.41e-175 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
LNENKMEB_00388 4.7e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
LNENKMEB_00389 9.38e-167 kipR - - K - - - Transcriptional regulator
LNENKMEB_00390 9.09e-149 ycsK - - E - - - anatomical structure formation involved in morphogenesis
LNENKMEB_00392 9.52e-72 yczJ - - S - - - biosynthesis
LNENKMEB_00393 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
LNENKMEB_00394 1.05e-220 ycsN - - S - - - Oxidoreductase
LNENKMEB_00395 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
LNENKMEB_00396 0.0 ydaB - - IQ - - - acyl-CoA ligase
LNENKMEB_00397 7.7e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LNENKMEB_00398 2.75e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
LNENKMEB_00399 1.92e-147 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LNENKMEB_00400 3.69e-101 ydaG - - S - - - general stress protein
LNENKMEB_00401 1.53e-177 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LNENKMEB_00402 5.59e-64 ydzA - - EGP - - - Domain of unknown function (DUF3817)
LNENKMEB_00403 7.97e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LNENKMEB_00404 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LNENKMEB_00405 8.41e-260 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
LNENKMEB_00406 6.29e-188 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
LNENKMEB_00407 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
LNENKMEB_00408 4.54e-303 ydaM - - M - - - Glycosyl transferase family group 2
LNENKMEB_00409 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
LNENKMEB_00410 0.0 ydaO - - E - - - amino acid
LNENKMEB_00411 3.75e-98 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LNENKMEB_00412 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LNENKMEB_00413 1.21e-62 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LNENKMEB_00414 2.17e-99 - - - - - - - -
LNENKMEB_00416 1.31e-152 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
LNENKMEB_00417 2.61e-53 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
LNENKMEB_00419 4.42e-11 - - - - - - - -
LNENKMEB_00421 4.37e-115 - - - - - - - -
LNENKMEB_00422 6e-130 - - - - - - - -
LNENKMEB_00423 2.14e-53 - - - - - - - -
LNENKMEB_00424 3.77e-288 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LNENKMEB_00426 1.95e-45 ydaT - - - - - - -
LNENKMEB_00427 3.89e-96 yvaD - - S - - - Family of unknown function (DUF5360)
LNENKMEB_00428 2.87e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
LNENKMEB_00429 2.29e-183 ydbA - - P - - - EcsC protein family
LNENKMEB_00430 6.55e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
LNENKMEB_00431 9.34e-85 ydbB - - G - - - Cupin domain
LNENKMEB_00432 2.12e-81 ydbC - - S - - - Domain of unknown function (DUF4937
LNENKMEB_00433 1.64e-199 ydbD - - P ko:K07217 - ko00000 Catalase
LNENKMEB_00434 8.63e-252 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LNENKMEB_00435 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LNENKMEB_00436 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LNENKMEB_00437 3.91e-287 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LNENKMEB_00438 8.61e-231 ydbI - - S - - - AI-2E family transporter
LNENKMEB_00439 9.66e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_00440 2.44e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LNENKMEB_00441 2.29e-70 ydbL - - - - - - -
LNENKMEB_00442 7.51e-262 ydbM - - I - - - acyl-CoA dehydrogenase
LNENKMEB_00443 1.13e-15 - - - S - - - Fur-regulated basic protein B
LNENKMEB_00444 1.09e-12 - - - S - - - Fur-regulated basic protein A
LNENKMEB_00445 2e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LNENKMEB_00446 6.46e-74 ydbP - - CO - - - Thioredoxin
LNENKMEB_00447 2.16e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LNENKMEB_00448 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LNENKMEB_00449 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LNENKMEB_00450 6.83e-109 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
LNENKMEB_00451 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
LNENKMEB_00452 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
LNENKMEB_00453 1.32e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LNENKMEB_00454 1.57e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
LNENKMEB_00455 1.7e-280 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LNENKMEB_00456 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LNENKMEB_00457 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LNENKMEB_00458 1.43e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
LNENKMEB_00459 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
LNENKMEB_00460 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LNENKMEB_00461 3.6e-241 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
LNENKMEB_00462 2.8e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
LNENKMEB_00463 7.1e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LNENKMEB_00464 1.14e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LNENKMEB_00465 5.75e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
LNENKMEB_00466 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
LNENKMEB_00467 1.78e-21 - - - - - - - -
LNENKMEB_00468 1.49e-76 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LNENKMEB_00476 1.35e-124 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
LNENKMEB_00477 6.17e-96 - - - S - - - SnoaL-like polyketide cyclase
LNENKMEB_00478 1.49e-179 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
LNENKMEB_00479 2.73e-92 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
LNENKMEB_00480 2.29e-193 - - - S - - - Serine aminopeptidase, S33
LNENKMEB_00481 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
LNENKMEB_00482 2.04e-110 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
LNENKMEB_00483 8.35e-94 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
LNENKMEB_00484 3.46e-84 - - - S - - - YjbR
LNENKMEB_00485 4.07e-97 ywnA - - K - - - Transcriptional regulator
LNENKMEB_00486 3.16e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
LNENKMEB_00487 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
LNENKMEB_00488 5.92e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
LNENKMEB_00489 4.82e-155 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LNENKMEB_00490 4.4e-126 - - - S - - - Protein of unknown function (DUF2812)
LNENKMEB_00491 3.34e-67 - - - K - - - Transcriptional regulator PadR-like family
LNENKMEB_00492 7.19e-234 - - - S - - - Patatin-like phospholipase
LNENKMEB_00493 2.47e-101 - - - S - - - DinB superfamily
LNENKMEB_00494 1.49e-84 - - - G - - - Cupin domain
LNENKMEB_00496 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
LNENKMEB_00497 2.63e-41 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LNENKMEB_00498 3.3e-194 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
LNENKMEB_00499 1.5e-254 trkA - - P ko:K07222 - ko00000 Oxidoreductase
LNENKMEB_00501 5.46e-189 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
LNENKMEB_00503 1.01e-254 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
LNENKMEB_00504 9.09e-75 ydeH - - - - - - -
LNENKMEB_00505 5.27e-110 - - - F - - - nucleoside 2-deoxyribosyltransferase
LNENKMEB_00506 3.78e-248 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LNENKMEB_00507 2.51e-188 - - - Q - - - ubiE/COQ5 methyltransferase family
LNENKMEB_00508 1.1e-192 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7 - H ko:K00941,ko:K14153 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LNENKMEB_00509 6.9e-298 - - - G - - - Haloacid dehalogenase-like hydrolase
LNENKMEB_00510 4.45e-207 - - - S - - - Sodium Bile acid symporter family
LNENKMEB_00511 9.05e-258 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
LNENKMEB_00512 7.29e-87 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
LNENKMEB_00513 3.22e-287 nhaC_1 - - C - - - antiporter
LNENKMEB_00514 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
LNENKMEB_00515 1.2e-145 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_00517 1.62e-245 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
LNENKMEB_00518 1.2e-132 ydeS - - K - - - Transcriptional regulator
LNENKMEB_00519 5.26e-202 ydeK - - EG - - - -transporter
LNENKMEB_00520 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LNENKMEB_00521 5.09e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
LNENKMEB_00522 3.42e-33 yraE - - - ko:K06440 - ko00000 -
LNENKMEB_00523 2.5e-281 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LNENKMEB_00524 8.22e-85 yraF - - M - - - Spore coat protein
LNENKMEB_00525 1.71e-49 yraG - - - ko:K06440 - ko00000 -
LNENKMEB_00526 7.63e-279 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_00527 1.39e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LNENKMEB_00528 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
LNENKMEB_00529 1.97e-170 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
LNENKMEB_00530 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
LNENKMEB_00531 3.71e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
LNENKMEB_00532 1.6e-189 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LNENKMEB_00533 4.41e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
LNENKMEB_00534 2.35e-269 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
LNENKMEB_00535 1.86e-286 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LNENKMEB_00536 2.24e-200 - - - K - - - Helix-turn-helix XRE-family like proteins
LNENKMEB_00537 9e-158 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
LNENKMEB_00538 1.46e-106 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
LNENKMEB_00539 4.83e-15 bltR - - K - - - helix_turn_helix, mercury resistance
LNENKMEB_00540 2.25e-145 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LNENKMEB_00541 6.64e-188 - - - Q - - - ubiE/COQ5 methyltransferase family
LNENKMEB_00542 6.25e-107 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
LNENKMEB_00545 2.55e-91 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
LNENKMEB_00546 1.27e-151 ydhC - - K - - - FCD
LNENKMEB_00547 7.91e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LNENKMEB_00550 0.0 pbpE - - V - - - Beta-lactamase
LNENKMEB_00552 4.12e-126 ydhK - - M - - - Protein of unknown function (DUF1541)
LNENKMEB_00553 3.18e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
LNENKMEB_00554 2.06e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
LNENKMEB_00555 3.25e-154 - - - K ko:K05799 - ko00000,ko03000 FCD
LNENKMEB_00556 1.23e-276 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
LNENKMEB_00557 1.48e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
LNENKMEB_00558 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LNENKMEB_00559 3.63e-136 yvdT_1 - - K - - - Transcriptional regulator
LNENKMEB_00560 0.0 ybeC - - E - - - amino acid
LNENKMEB_00561 4.41e-214 ydhU - - P ko:K07217 - ko00000 Catalase
LNENKMEB_00562 2.06e-112 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
LNENKMEB_00563 2.83e-237 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
LNENKMEB_00564 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LNENKMEB_00567 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LNENKMEB_00570 4.87e-234 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LNENKMEB_00571 1.82e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
LNENKMEB_00572 8.36e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
LNENKMEB_00573 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LNENKMEB_00574 9.22e-245 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LNENKMEB_00575 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
LNENKMEB_00576 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LNENKMEB_00577 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LNENKMEB_00578 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LNENKMEB_00579 1.65e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LNENKMEB_00580 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
LNENKMEB_00581 4.09e-165 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
LNENKMEB_00582 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LNENKMEB_00583 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LNENKMEB_00584 7.07e-51 - - - S - - - Protein of unknown function (DUF4064)
LNENKMEB_00585 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
LNENKMEB_00586 1.02e-256 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
LNENKMEB_00587 4.54e-316 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
LNENKMEB_00588 4.24e-221 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
LNENKMEB_00589 5.98e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
LNENKMEB_00590 1.17e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
LNENKMEB_00591 1.55e-229 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LNENKMEB_00592 2.24e-162 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
LNENKMEB_00593 6.58e-200 ydjI - - S - - - virion core protein (lumpy skin disease virus)
LNENKMEB_00594 0.0 oatA - - I - - - Acyltransferase family
LNENKMEB_00595 1.13e-192 rsiV - - S - - - Protein of unknown function (DUF3298)
LNENKMEB_00596 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LNENKMEB_00597 1e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
LNENKMEB_00598 7.91e-83 ydjM - - M - - - Lytic transglycolase
LNENKMEB_00599 4.98e-195 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
LNENKMEB_00601 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
LNENKMEB_00602 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
LNENKMEB_00603 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LNENKMEB_00604 2.91e-197 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LNENKMEB_00605 6.84e-227 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
LNENKMEB_00606 2.69e-275 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LNENKMEB_00607 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
LNENKMEB_00608 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LNENKMEB_00609 3.32e-165 - - - K - - - Acetyltransferase (GNAT) domain
LNENKMEB_00610 4.67e-122 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LNENKMEB_00611 8.68e-317 - - - S - - - Domain of unknown function (DUF4179)
LNENKMEB_00612 1.75e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LNENKMEB_00613 2.02e-173 yebC - - M - - - Membrane
LNENKMEB_00615 4.41e-119 yebE - - S - - - UPF0316 protein
LNENKMEB_00616 6.56e-40 yebG - - S - - - NETI protein
LNENKMEB_00617 1.13e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LNENKMEB_00618 1.31e-286 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LNENKMEB_00619 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LNENKMEB_00620 4.13e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LNENKMEB_00621 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LNENKMEB_00622 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LNENKMEB_00623 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LNENKMEB_00624 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LNENKMEB_00625 2.53e-242 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LNENKMEB_00626 7.3e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LNENKMEB_00627 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LNENKMEB_00628 3.29e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LNENKMEB_00629 4.18e-34 - - - S - - - Protein of unknown function (DUF2892)
LNENKMEB_00630 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
LNENKMEB_00631 4.95e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
LNENKMEB_00632 2.03e-67 yerC - - S - - - protein conserved in bacteria
LNENKMEB_00633 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
LNENKMEB_00634 1.76e-163 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LNENKMEB_00635 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LNENKMEB_00636 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LNENKMEB_00637 2.74e-286 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
LNENKMEB_00638 1.48e-247 yerI - - S - - - homoserine kinase type II (protein kinase fold)
LNENKMEB_00639 1.68e-157 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
LNENKMEB_00640 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LNENKMEB_00641 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LNENKMEB_00642 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LNENKMEB_00643 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LNENKMEB_00644 2.91e-193 yerO - - K - - - Transcriptional regulator
LNENKMEB_00645 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LNENKMEB_00646 4.95e-216 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LNENKMEB_00647 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LNENKMEB_00648 2.75e-26 - - - L - - - Recombinase zinc beta ribbon domain
LNENKMEB_00650 9.25e-270 - - - T - - - Nacht domain
LNENKMEB_00651 8.75e-262 - - - V ko:K07451 - ko00000,ko01000,ko02048 Domain of unknown function (DUF3578)
LNENKMEB_00654 5.79e-85 - - - S - - - Protein of unknown function, DUF600
LNENKMEB_00655 1.27e-109 - - - S - - - Protein of unknown function, DUF600
LNENKMEB_00656 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
LNENKMEB_00657 1.05e-24 - - - - - - - -
LNENKMEB_00658 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
LNENKMEB_00660 4.61e-61 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
LNENKMEB_00661 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
LNENKMEB_00662 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
LNENKMEB_00663 4.33e-127 yesJ - - K - - - Acetyltransferase (GNAT) family
LNENKMEB_00664 4.2e-05 - - - - - - - -
LNENKMEB_00665 3.01e-155 yetF - - S - - - membrane
LNENKMEB_00666 6.42e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
LNENKMEB_00667 7.63e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LNENKMEB_00668 4.42e-197 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LNENKMEB_00669 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
LNENKMEB_00670 1.06e-72 - - - H - - - riboflavin kinase activity
LNENKMEB_00671 2.19e-136 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
LNENKMEB_00673 2.08e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
LNENKMEB_00674 5.52e-261 yetM - - CH - - - FAD binding domain
LNENKMEB_00675 1.38e-251 yetN - - S - - - Protein of unknown function (DUF3900)
LNENKMEB_00676 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LNENKMEB_00677 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LNENKMEB_00678 1.02e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
LNENKMEB_00679 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
LNENKMEB_00680 2.31e-230 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
LNENKMEB_00681 1.46e-284 yfnE - - S - - - Glycosyltransferase like family 2
LNENKMEB_00682 8.46e-240 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
LNENKMEB_00683 2.7e-278 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LNENKMEB_00684 8.39e-313 yfnA - - E ko:K03294 - ko00000 amino acid
LNENKMEB_00685 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LNENKMEB_00686 1.16e-168 yfmS - - NT - - - chemotaxis protein
LNENKMEB_00687 2.1e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LNENKMEB_00688 2.43e-265 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
LNENKMEB_00689 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LNENKMEB_00690 7.16e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
LNENKMEB_00691 3.43e-262 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
LNENKMEB_00692 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LNENKMEB_00693 1.53e-265 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
LNENKMEB_00694 8.07e-84 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
LNENKMEB_00695 4.71e-239 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
LNENKMEB_00696 1.1e-30 - - - S - - - Protein of unknown function (DUF3212)
LNENKMEB_00697 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
LNENKMEB_00698 2.18e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
LNENKMEB_00699 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LNENKMEB_00704 0.0 ywpD - - T - - - Histidine kinase
LNENKMEB_00705 1.24e-193 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
LNENKMEB_00706 0.0 - - - M - - - cell wall anchor domain
LNENKMEB_00707 4.77e-105 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
LNENKMEB_00708 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LNENKMEB_00709 1.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LNENKMEB_00710 5.62e-226 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
LNENKMEB_00711 8.19e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LNENKMEB_00712 8.08e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LNENKMEB_00713 1.67e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LNENKMEB_00714 9.63e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LNENKMEB_00715 2.51e-158 yflK - - S - - - protein conserved in bacteria
LNENKMEB_00716 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
LNENKMEB_00717 1.98e-26 yflI - - - - - - -
LNENKMEB_00718 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
LNENKMEB_00719 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LNENKMEB_00720 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LNENKMEB_00721 1.87e-98 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
LNENKMEB_00722 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LNENKMEB_00723 8.46e-84 ydhN1 - - S - - - Domain of unknown function (DUF1992)
LNENKMEB_00724 1.43e-104 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LNENKMEB_00725 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
LNENKMEB_00726 7.28e-51 ydgB - - S - - - Spore germination protein gerPA/gerPF
LNENKMEB_00727 4.49e-313 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LNENKMEB_00728 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
LNENKMEB_00729 4.8e-165 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
LNENKMEB_00730 1.45e-158 frp - - C - - - nitroreductase
LNENKMEB_00731 4.93e-166 yibF - - S - - - YibE/F-like protein
LNENKMEB_00732 6.6e-257 yibE - - S - - - YibE/F-like protein
LNENKMEB_00733 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
LNENKMEB_00734 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LNENKMEB_00735 9.13e-239 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LNENKMEB_00736 6.12e-210 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LNENKMEB_00737 4.11e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LNENKMEB_00738 4.7e-250 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LNENKMEB_00739 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
LNENKMEB_00740 1.69e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LNENKMEB_00741 1.76e-68 yfkI - - S - - - gas vesicle protein
LNENKMEB_00742 1.37e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LNENKMEB_00743 6.71e-12 - - - - - - - -
LNENKMEB_00744 2.48e-69 - - - L - - - COG2963 Transposase and inactivated derivatives
LNENKMEB_00745 2.72e-175 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
LNENKMEB_00746 1.45e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LNENKMEB_00747 8.42e-239 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
LNENKMEB_00748 5.66e-186 yfkD - - S - - - YfkD-like protein
LNENKMEB_00749 5.2e-189 yfkC - - M - - - Mechanosensitive ion channel
LNENKMEB_00750 1.97e-280 yfkA - - S - - - YfkB-like domain
LNENKMEB_00751 7.99e-37 yfjT - - - - - - -
LNENKMEB_00752 4.36e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
LNENKMEB_00753 2.39e-194 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LNENKMEB_00755 2.24e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
LNENKMEB_00756 1.72e-208 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LNENKMEB_00757 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LNENKMEB_00758 2.15e-67 - - - S - - - YfzA-like protein
LNENKMEB_00760 2.97e-245 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LNENKMEB_00761 1.11e-115 yfjM - - S - - - Psort location Cytoplasmic, score
LNENKMEB_00762 5.55e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LNENKMEB_00763 3.08e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LNENKMEB_00764 1.09e-271 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LNENKMEB_00765 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LNENKMEB_00766 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
LNENKMEB_00767 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
LNENKMEB_00768 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LNENKMEB_00769 1.28e-177 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
LNENKMEB_00770 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LNENKMEB_00771 0.0 - - - M - - - Peptidase_G2, IMC autoproteolytic cleavage domain
LNENKMEB_00772 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
LNENKMEB_00773 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LNENKMEB_00774 5.54e-82 yfiD3 - - S - - - DoxX
LNENKMEB_00775 4.72e-205 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
LNENKMEB_00776 2.08e-214 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LNENKMEB_00777 5.62e-126 padR - - K - - - transcriptional
LNENKMEB_00778 4.22e-143 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LNENKMEB_00779 4.65e-237 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LNENKMEB_00781 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
LNENKMEB_00782 2.87e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
LNENKMEB_00783 1.14e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
LNENKMEB_00784 0.0 yfiU - - EGP - - - the major facilitator superfamily
LNENKMEB_00785 1.38e-108 yfiV - - K - - - transcriptional
LNENKMEB_00786 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LNENKMEB_00787 1.59e-212 yfhB - - S - - - PhzF family
LNENKMEB_00788 1.17e-137 yfhC - - C - - - nitroreductase
LNENKMEB_00789 3.61e-34 yfhD - - S - - - YfhD-like protein
LNENKMEB_00790 1.72e-214 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
LNENKMEB_00791 7.4e-182 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
LNENKMEB_00792 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
LNENKMEB_00793 1.16e-267 yfhI - - EGP - - - -transporter
LNENKMEB_00795 2.45e-216 mpr - - M - - - Belongs to the peptidase S1B family
LNENKMEB_00796 2.57e-59 yfhJ - - S - - - WVELL protein
LNENKMEB_00797 9.84e-123 yfhK - - T - - - Bacterial SH3 domain homologues
LNENKMEB_00798 1.48e-57 yfhL - - S - - - SdpI/YhfL protein family
LNENKMEB_00799 9.66e-219 - - - S - - - Alpha/beta hydrolase family
LNENKMEB_00800 5.49e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LNENKMEB_00801 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
LNENKMEB_00802 1.7e-235 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
LNENKMEB_00803 3.2e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
LNENKMEB_00804 2.54e-50 yfhS - - - - - - -
LNENKMEB_00805 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LNENKMEB_00806 4.77e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
LNENKMEB_00807 1.4e-49 ygaB - - S - - - YgaB-like protein
LNENKMEB_00808 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
LNENKMEB_00809 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
LNENKMEB_00810 1.91e-239 ygaE - - S - - - Membrane
LNENKMEB_00811 2.79e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LNENKMEB_00812 1.39e-111 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
LNENKMEB_00813 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LNENKMEB_00814 4.67e-75 ygzB - - S - - - UPF0295 protein
LNENKMEB_00815 1.53e-210 ygxA - - S - - - Nucleotidyltransferase-like
LNENKMEB_00816 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LNENKMEB_00833 0.0 - - - C - - - Na+/H+ antiporter family
LNENKMEB_00834 4.02e-171 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
LNENKMEB_00835 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LNENKMEB_00836 0.0 ygaK - - C - - - Berberine and berberine like
LNENKMEB_00838 1.04e-289 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
LNENKMEB_00839 2.02e-179 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LNENKMEB_00840 4.37e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LNENKMEB_00841 7.73e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LNENKMEB_00842 3.29e-168 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LNENKMEB_00843 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LNENKMEB_00844 1.15e-234 - - - S ko:K07045 - ko00000 Amidohydrolase
LNENKMEB_00845 4.5e-180 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LNENKMEB_00846 2.13e-230 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
LNENKMEB_00847 8.27e-186 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LNENKMEB_00848 2.47e-272 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
LNENKMEB_00849 5.64e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LNENKMEB_00850 5.25e-106 ygaO - - - - - - -
LNENKMEB_00852 4.53e-146 yhzB - - S - - - B3/4 domain
LNENKMEB_00853 1.4e-285 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LNENKMEB_00854 7.27e-226 yhbB - - S - - - Putative amidase domain
LNENKMEB_00855 4.84e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LNENKMEB_00856 1.39e-140 yhbD - - K - - - Protein of unknown function (DUF4004)
LNENKMEB_00857 3.45e-86 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LNENKMEB_00858 2.02e-94 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LNENKMEB_00859 1.23e-07 - - - - - - - -
LNENKMEB_00860 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
LNENKMEB_00861 1.77e-280 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
LNENKMEB_00862 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
LNENKMEB_00863 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
LNENKMEB_00864 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
LNENKMEB_00865 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LNENKMEB_00866 1.41e-72 yhcC - - - - - - -
LNENKMEB_00867 2.33e-66 - - - - - - - -
LNENKMEB_00868 1.64e-81 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_00869 1.78e-162 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_00870 1.93e-214 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_00871 1.1e-209 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LNENKMEB_00872 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
LNENKMEB_00873 1.01e-190 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LNENKMEB_00874 3.92e-248 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
LNENKMEB_00875 1.29e-293 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LNENKMEB_00876 4.67e-80 yhcM - - - - - - -
LNENKMEB_00877 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LNENKMEB_00878 1.12e-205 yhcP - - - - - - -
LNENKMEB_00879 1.81e-150 yhcQ - - M - - - Spore coat protein
LNENKMEB_00880 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LNENKMEB_00881 4.55e-137 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
LNENKMEB_00882 9.64e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LNENKMEB_00883 6.3e-91 yhcU - - S - - - Family of unknown function (DUF5365)
LNENKMEB_00884 6.12e-91 yhcV - - S - - - COG0517 FOG CBS domain
LNENKMEB_00885 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
LNENKMEB_00886 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LNENKMEB_00887 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LNENKMEB_00888 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LNENKMEB_00889 8.1e-199 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LNENKMEB_00890 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LNENKMEB_00891 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LNENKMEB_00892 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
LNENKMEB_00893 3.6e-138 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_00894 9.99e-99 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_00895 1.05e-143 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LNENKMEB_00896 1.02e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
LNENKMEB_00897 6.98e-53 yhdB - - S - - - YhdB-like protein
LNENKMEB_00898 6.94e-70 yhdC - - S - - - Protein of unknown function (DUF3889)
LNENKMEB_00899 1.41e-295 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LNENKMEB_00900 1.32e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
LNENKMEB_00901 0.0 ygxB - - M - - - Conserved TM helix
LNENKMEB_00902 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
LNENKMEB_00903 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
LNENKMEB_00904 2.62e-176 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LNENKMEB_00905 7e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_00906 5.72e-262 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LNENKMEB_00907 9.14e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LNENKMEB_00908 8.9e-317 yhdG - - E ko:K03294 - ko00000 amino acid
LNENKMEB_00909 5.92e-267 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LNENKMEB_00910 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
LNENKMEB_00911 1.69e-257 yhdL - - S - - - Sigma factor regulator N-terminal
LNENKMEB_00912 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LNENKMEB_00913 3.75e-141 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LNENKMEB_00914 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LNENKMEB_00915 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
LNENKMEB_00916 3.33e-285 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LNENKMEB_00917 7.8e-301 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LNENKMEB_00918 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
LNENKMEB_00919 2.12e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LNENKMEB_00920 4.77e-77 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LNENKMEB_00921 5.21e-165 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LNENKMEB_00922 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
LNENKMEB_00923 6.68e-262 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
LNENKMEB_00924 5.67e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LNENKMEB_00925 1.7e-201 nodB1 - - G - - - deacetylase
LNENKMEB_00926 1.19e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LNENKMEB_00927 1.22e-114 pksA - - K - - - Transcriptional regulator
LNENKMEB_00928 1.33e-124 ymcC - - S - - - Membrane
LNENKMEB_00929 2.91e-109 - - - T - - - universal stress protein
LNENKMEB_00931 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LNENKMEB_00932 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LNENKMEB_00933 6.68e-143 yheG - - GM - - - NAD(P)H-binding
LNENKMEB_00935 9.47e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
LNENKMEB_00936 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
LNENKMEB_00937 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
LNENKMEB_00938 1.32e-273 yheC - - HJ - - - YheC/D like ATP-grasp
LNENKMEB_00939 1.36e-264 yheB - - S - - - Belongs to the UPF0754 family
LNENKMEB_00940 9.47e-70 yheA - - S - - - Belongs to the UPF0342 family
LNENKMEB_00941 4.79e-256 yhaZ - - L - - - DNA alkylation repair enzyme
LNENKMEB_00942 8.46e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
LNENKMEB_00943 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
LNENKMEB_00944 1.92e-316 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
LNENKMEB_00945 1.41e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
LNENKMEB_00946 1.87e-113 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LNENKMEB_00948 4.11e-175 yhaR - - I - - - enoyl-CoA hydratase
LNENKMEB_00949 7.01e-20 - - - S - - - YhzD-like protein
LNENKMEB_00950 3.92e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_00951 1.13e-275 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
LNENKMEB_00952 1.24e-298 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
LNENKMEB_00953 0.0 yhaN - - L - - - AAA domain
LNENKMEB_00954 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
LNENKMEB_00955 2.02e-43 yhaL - - S - - - Sporulation protein YhaL
LNENKMEB_00956 1.93e-183 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LNENKMEB_00957 1.29e-123 yhaK - - S - - - Putative zincin peptidase
LNENKMEB_00958 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
LNENKMEB_00959 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
LNENKMEB_00960 2.74e-54 yhaH - - S - - - YtxH-like protein
LNENKMEB_00961 2.55e-24 - - - - - - - -
LNENKMEB_00962 1.43e-100 trpP - - S - - - Tryptophan transporter TrpP
LNENKMEB_00963 2.81e-257 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LNENKMEB_00964 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LNENKMEB_00965 1.82e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
LNENKMEB_00966 6.41e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LNENKMEB_00967 8.65e-162 ecsC - - S - - - EcsC protein family
LNENKMEB_00968 2.95e-284 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LNENKMEB_00969 9.36e-310 yhfA - - C - - - membrane
LNENKMEB_00970 3.1e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
LNENKMEB_00971 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LNENKMEB_00972 1.04e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LNENKMEB_00973 5.24e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
LNENKMEB_00974 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LNENKMEB_00975 3.63e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_00976 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
LNENKMEB_00977 8.41e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LNENKMEB_00979 2.57e-251 yhfE - - G - - - peptidase M42
LNENKMEB_00980 3.43e-282 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LNENKMEB_00982 6.93e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LNENKMEB_00983 4.37e-240 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LNENKMEB_00984 8.98e-143 yhfK - - GM - - - NmrA-like family
LNENKMEB_00985 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LNENKMEB_00986 2.38e-86 yhfM - - - - - - -
LNENKMEB_00987 2.24e-301 yhfN - - O - - - Peptidase M48
LNENKMEB_00988 3.46e-265 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LNENKMEB_00989 3.7e-201 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LNENKMEB_00990 6.03e-134 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
LNENKMEB_00991 8.65e-254 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LNENKMEB_00992 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LNENKMEB_00993 1.86e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LNENKMEB_00994 2.78e-277 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
LNENKMEB_00995 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
LNENKMEB_00996 1.35e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LNENKMEB_00997 5.7e-44 yhzC - - S - - - IDEAL
LNENKMEB_00998 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
LNENKMEB_00999 3.25e-55 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
LNENKMEB_01000 9.56e-89 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
LNENKMEB_01001 1.41e-119 - - - S - - - MepB protein
LNENKMEB_01002 4.26e-161 yrpD - - S - - - Domain of unknown function, YrpD
LNENKMEB_01003 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
LNENKMEB_01004 2.64e-63 - - - S - - - Belongs to the UPF0145 family
LNENKMEB_01005 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LNENKMEB_01006 1.37e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
LNENKMEB_01007 4.12e-79 yhjD - - - - - - -
LNENKMEB_01008 1.64e-144 yhjE - - S - - - SNARE associated Golgi protein
LNENKMEB_01009 9.51e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LNENKMEB_01010 0.0 yhjG - - CH - - - FAD binding domain
LNENKMEB_01011 1.03e-123 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
LNENKMEB_01012 4.88e-262 yhjN - - S ko:K07120 - ko00000 membrane
LNENKMEB_01013 9.23e-269 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LNENKMEB_01014 2.72e-142 - - - K - - - QacR-like protein, C-terminal region
LNENKMEB_01015 1.79e-122 yhjR - - S - - - Rubrerythrin
LNENKMEB_01016 2.46e-160 ydfS - - S - - - Protein of unknown function (DUF421)
LNENKMEB_01017 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
LNENKMEB_01018 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LNENKMEB_01019 4.7e-283 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LNENKMEB_01020 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
LNENKMEB_01021 1.53e-66 yisB - - V - - - COG1403 Restriction endonuclease
LNENKMEB_01022 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
LNENKMEB_01023 1.61e-84 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
LNENKMEB_01024 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
LNENKMEB_01025 3.46e-108 gerPC - - S ko:K06301 - ko00000 Spore germination protein
LNENKMEB_01026 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
LNENKMEB_01027 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
LNENKMEB_01028 2.25e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
LNENKMEB_01029 1.54e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LNENKMEB_01030 2.22e-78 yisL - - S - - - UPF0344 protein
LNENKMEB_01031 1.86e-124 yisN - - S - - - Protein of unknown function (DUF2777)
LNENKMEB_01032 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LNENKMEB_01033 5.64e-173 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
LNENKMEB_01034 8.75e-310 yisQ - - V - - - Mate efflux family protein
LNENKMEB_01035 1.35e-205 yisR - - K - - - Transcriptional regulator
LNENKMEB_01036 3.11e-116 yisT - - S - - - DinB family
LNENKMEB_01037 7.29e-97 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
LNENKMEB_01038 9.17e-237 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LNENKMEB_01039 6.14e-108 yisX - - S - - - Pentapeptide repeats (9 copies)
LNENKMEB_01040 3.78e-106 - - - S - - - Acetyltransferase (GNAT) domain
LNENKMEB_01041 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LNENKMEB_01042 6.39e-79 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
LNENKMEB_01043 1.59e-206 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
LNENKMEB_01044 2.18e-221 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
LNENKMEB_01045 1.16e-67 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
LNENKMEB_01046 3.39e-230 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
LNENKMEB_01047 5.13e-307 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
LNENKMEB_01049 9.13e-202 yitS - - S - - - protein conserved in bacteria
LNENKMEB_01050 1.61e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LNENKMEB_01051 6.41e-106 ipi - - S - - - Intracellular proteinase inhibitor
LNENKMEB_01052 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
LNENKMEB_01053 1.49e-11 - - - - - - - -
LNENKMEB_01054 1.52e-198 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LNENKMEB_01055 1.56e-183 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LNENKMEB_01056 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
LNENKMEB_01057 8.23e-106 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LNENKMEB_01058 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
LNENKMEB_01059 1.88e-118 yitZ - - G - - - Major Facilitator Superfamily
LNENKMEB_01060 1.67e-251 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LNENKMEB_01061 1.8e-290 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LNENKMEB_01062 2.46e-173 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
LNENKMEB_01063 4.64e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
LNENKMEB_01064 1.69e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LNENKMEB_01065 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
LNENKMEB_01066 7.1e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LNENKMEB_01067 7.21e-39 yjzC - - S - - - YjzC-like protein
LNENKMEB_01068 5.24e-33 yjzD - - S - - - Protein of unknown function (DUF2929)
LNENKMEB_01069 6.65e-180 yjaU - - I - - - carboxylic ester hydrolase activity
LNENKMEB_01070 9.68e-134 yjaV - - - - - - -
LNENKMEB_01071 4.67e-213 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
LNENKMEB_01072 1.85e-36 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
LNENKMEB_01073 2.82e-44 yjzB - - - - - - -
LNENKMEB_01074 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LNENKMEB_01075 3.17e-299 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LNENKMEB_01076 2.5e-188 yjaZ - - O - - - Zn-dependent protease
LNENKMEB_01077 3.41e-231 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LNENKMEB_01078 7.23e-238 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LNENKMEB_01079 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
LNENKMEB_01080 4.24e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LNENKMEB_01081 3.87e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LNENKMEB_01082 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
LNENKMEB_01083 2.51e-234 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
LNENKMEB_01084 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LNENKMEB_01085 1.46e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LNENKMEB_01086 3.59e-210 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LNENKMEB_01087 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LNENKMEB_01088 2.19e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LNENKMEB_01089 1.49e-296 - - - S - - - Putative glycosyl hydrolase domain
LNENKMEB_01090 4.4e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LNENKMEB_01091 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LNENKMEB_01092 2.77e-141 yjbE - - P - - - Integral membrane protein TerC family
LNENKMEB_01093 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LNENKMEB_01094 3.3e-281 coiA - - S ko:K06198 - ko00000 Competence protein
LNENKMEB_01095 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LNENKMEB_01096 3.14e-27 - - - - - - - -
LNENKMEB_01097 2.46e-219 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LNENKMEB_01098 1.22e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
LNENKMEB_01099 3.28e-138 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LNENKMEB_01100 3.48e-128 yjbK - - S - - - protein conserved in bacteria
LNENKMEB_01101 3.5e-81 yjbL - - S - - - Belongs to the UPF0738 family
LNENKMEB_01102 9.01e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
LNENKMEB_01103 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LNENKMEB_01104 2.86e-212 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LNENKMEB_01105 1.84e-184 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LNENKMEB_01106 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LNENKMEB_01107 2.71e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LNENKMEB_01108 1.63e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
LNENKMEB_01109 1.37e-269 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
LNENKMEB_01110 4.53e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
LNENKMEB_01111 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LNENKMEB_01112 1.36e-241 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LNENKMEB_01113 1.06e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LNENKMEB_01114 6.85e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LNENKMEB_01115 3.38e-125 yjbX - - S - - - Spore coat protein
LNENKMEB_01116 9.62e-105 cotZ - - S ko:K06344 - ko00000 Spore coat protein
LNENKMEB_01117 1.61e-116 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
LNENKMEB_01118 4.33e-99 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
LNENKMEB_01119 8.38e-36 cotW - - - ko:K06341 - ko00000 -
LNENKMEB_01120 2.67e-68 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
LNENKMEB_01121 2.92e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
LNENKMEB_01124 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LNENKMEB_01125 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
LNENKMEB_01126 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LNENKMEB_01127 1.23e-48 - - - - - - - -
LNENKMEB_01128 3.79e-165 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
LNENKMEB_01129 7.6e-159 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LNENKMEB_01130 5.01e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LNENKMEB_01131 4.32e-48 - - - K - - - SpoVT / AbrB like domain
LNENKMEB_01133 7.39e-98 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LNENKMEB_01134 5.73e-120 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
LNENKMEB_01135 1.23e-164 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
LNENKMEB_01136 3.37e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LNENKMEB_01137 1.15e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LNENKMEB_01139 2.14e-224 int7 - - L - - - Belongs to the 'phage' integrase family
LNENKMEB_01140 6.11e-64 xkdA - - E - - - IrrE N-terminal-like domain
LNENKMEB_01141 0.000748 - - - S - - - Short C-terminal domain
LNENKMEB_01142 1.65e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
LNENKMEB_01143 1.73e-22 - - - K - - - sequence-specific DNA binding
LNENKMEB_01144 5.95e-22 - - - S - - - Helix-turn-helix domain
LNENKMEB_01145 3.4e-51 - - - S - - - DNA binding
LNENKMEB_01146 3.27e-110 - - - - - - - -
LNENKMEB_01151 8.9e-127 - - - - - - - -
LNENKMEB_01152 6.3e-88 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
LNENKMEB_01154 3.01e-98 yqaL - - L - - - DnaD domain protein
LNENKMEB_01155 5.97e-102 yqaM - - L - - - IstB-like ATP binding protein
LNENKMEB_01157 5.33e-28 - - - S - - - YopX protein
LNENKMEB_01158 4.77e-59 - - - S - - - Protein of unknown function (DUF1064)
LNENKMEB_01160 1.16e-23 yqaO - - S - - - Phage-like element PBSX protein XtrA
LNENKMEB_01164 1.27e-60 - - - - - - - -
LNENKMEB_01166 1.38e-86 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LNENKMEB_01168 1.74e-17 - - - K - - - Transcriptional regulator
LNENKMEB_01170 8.26e-61 - - - L ko:K07474 - ko00000 Terminase small subunit
LNENKMEB_01171 1.11e-247 - - - S - - - Phage terminase large subunit
LNENKMEB_01172 2.62e-148 - - - S - - - Phage portal protein, SPP1 Gp6-like
LNENKMEB_01173 6.65e-115 - - - S - - - Phage Mu protein F like protein
LNENKMEB_01174 7.62e-56 - - - S - - - Phage minor structural protein GP20
LNENKMEB_01176 2.94e-141 gpG - - - - - - -
LNENKMEB_01178 2.05e-36 - - - S - - - Phage gp6-like head-tail connector protein
LNENKMEB_01179 7.37e-38 - - - S - - - Phage head-tail joining protein
LNENKMEB_01180 6.4e-50 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LNENKMEB_01181 1.4e-38 - - - S - - - Protein of unknown function (DUF3168)
LNENKMEB_01182 1.86e-38 - - - S - - - Phage tail tube protein
LNENKMEB_01185 1.44e-168 - - - - - - - -
LNENKMEB_01187 4.25e-246 - - - S - - - peptidoglycan catabolic process
LNENKMEB_01192 1.16e-78 - - - S - - - Pfam:Phage_holin_4_1
LNENKMEB_01193 1.33e-158 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LNENKMEB_01194 1.19e-38 - - - S - - - SMI1-KNR4 cell-wall
LNENKMEB_01195 8.63e-244 - - - M - - - nucleic acid phosphodiester bond hydrolysis
LNENKMEB_01197 1.64e-144 - - - S - - - Macro domain
LNENKMEB_01198 5.71e-121 - - - S - - - Domain of unknown function (DUF4433)
LNENKMEB_01199 1.18e-72 - - - - - - - -
LNENKMEB_01200 5.51e-42 - - - S - - - Bacterial EndoU nuclease
LNENKMEB_01201 3.68e-23 - - - L ko:K21487 - ko00000,ko01000,ko02048 Belongs to the WXG100 family
LNENKMEB_01202 3.43e-106 - - - - - - - -
LNENKMEB_01204 1.62e-165 - - - - - - - -
LNENKMEB_01206 2.12e-104 - - - S - - - Alpha beta hydrolase
LNENKMEB_01207 7.44e-66 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
LNENKMEB_01208 1.88e-95 - - - E - - - phosphoribosylanthranilate isomerase activity
LNENKMEB_01210 1.41e-211 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
LNENKMEB_01211 2.2e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
LNENKMEB_01212 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
LNENKMEB_01213 3.68e-107 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LNENKMEB_01214 4.66e-282 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
LNENKMEB_01215 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LNENKMEB_01216 5.12e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LNENKMEB_01217 5.44e-277 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LNENKMEB_01218 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LNENKMEB_01219 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LNENKMEB_01220 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LNENKMEB_01221 5.89e-179 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LNENKMEB_01222 1.24e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
LNENKMEB_01225 2.48e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
LNENKMEB_01227 1.91e-31 yjfB - - S - - - Putative motility protein
LNENKMEB_01228 1.08e-92 yjgA - - T - - - Protein of unknown function (DUF2809)
LNENKMEB_01229 4.09e-131 yjgB - - S - - - Domain of unknown function (DUF4309)
LNENKMEB_01230 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
LNENKMEB_01231 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
LNENKMEB_01232 1.09e-291 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LNENKMEB_01233 1.53e-286 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LNENKMEB_01234 1e-39 - - - - - - - -
LNENKMEB_01235 7.93e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LNENKMEB_01236 8e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
LNENKMEB_01237 1.86e-167 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
LNENKMEB_01238 5.01e-228 yjlA - - EG - - - Putative multidrug resistance efflux transporter
LNENKMEB_01239 2.1e-119 yjlB - - S - - - Cupin domain
LNENKMEB_01240 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
LNENKMEB_01241 7.49e-281 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LNENKMEB_01242 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
LNENKMEB_01243 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
LNENKMEB_01244 5.06e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
LNENKMEB_01245 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
LNENKMEB_01246 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
LNENKMEB_01247 7.44e-112 - - - T - - - Transcriptional regulatory protein, C terminal
LNENKMEB_01248 9.87e-167 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LNENKMEB_01250 5.49e-175 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
LNENKMEB_01251 2.48e-69 - - - L - - - COG2963 Transposase and inactivated derivatives
LNENKMEB_01252 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
LNENKMEB_01253 1.02e-103 yjoA - - S - - - DinB family
LNENKMEB_01254 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LNENKMEB_01256 2.37e-221 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LNENKMEB_01257 9.51e-81 yjqA - - S - - - Bacterial PH domain
LNENKMEB_01258 8.47e-141 yjqB - - S - - - phage-related replication protein
LNENKMEB_01259 7.99e-189 yjqC - - P ko:K07217 - ko00000 Catalase
LNENKMEB_01260 1.87e-144 xkdA - - E - - - IrrE N-terminal-like domain
LNENKMEB_01261 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
LNENKMEB_01263 7.52e-197 xkdC - - L - - - Bacterial dnaA protein
LNENKMEB_01267 1.07e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LNENKMEB_01268 4.8e-140 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
LNENKMEB_01269 9.59e-263 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
LNENKMEB_01270 1.26e-302 xkdE3 - - S - - - portal protein
LNENKMEB_01271 8.8e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
LNENKMEB_01272 8.3e-203 xkdG - - S - - - Phage capsid family
LNENKMEB_01273 2.17e-61 yqbG - - S - - - Protein of unknown function (DUF3199)
LNENKMEB_01274 2.35e-55 - - - S - - - Domain of unknown function (DUF3599)
LNENKMEB_01275 6.9e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
LNENKMEB_01276 6.08e-74 xkdJ - - - - - - -
LNENKMEB_01277 1.57e-20 - - - - - - - -
LNENKMEB_01278 2.31e-287 xkdK - - S - - - Phage tail sheath C-terminal domain
LNENKMEB_01279 8.21e-97 xkdM - - S - - - Phage tail tube protein
LNENKMEB_01280 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
LNENKMEB_01281 4.33e-27 - - - - - - - -
LNENKMEB_01282 4.37e-278 xkdO - - L - - - Transglycosylase SLT domain
LNENKMEB_01283 1.88e-144 xkdP - - S - - - Lysin motif
LNENKMEB_01284 7.63e-206 xkdQ - - G - - - NLP P60 protein
LNENKMEB_01285 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
LNENKMEB_01286 2.86e-76 xkdS - - S - - - Protein of unknown function (DUF2634)
LNENKMEB_01287 7.58e-213 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LNENKMEB_01288 2.48e-113 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
LNENKMEB_01289 5.16e-37 - - - - - - - -
LNENKMEB_01290 2.43e-229 - - - - - - - -
LNENKMEB_01292 5.6e-41 xkdX - - - - - - -
LNENKMEB_01293 5e-175 xepA - - - - - - -
LNENKMEB_01294 1.11e-50 xhlA - - S - - - Haemolysin XhlA
LNENKMEB_01295 4.7e-52 xhlB - - S - - - SPP1 phage holin
LNENKMEB_01296 2.99e-216 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
LNENKMEB_01297 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
LNENKMEB_01298 1.89e-172 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
LNENKMEB_01299 7.07e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
LNENKMEB_01300 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
LNENKMEB_01301 1.89e-311 steT - - E ko:K03294 - ko00000 amino acid
LNENKMEB_01302 2.9e-226 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LNENKMEB_01303 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LNENKMEB_01304 1.56e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LNENKMEB_01306 1.85e-276 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LNENKMEB_01307 0.0 yubD - - P - - - Major Facilitator Superfamily
LNENKMEB_01309 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
LNENKMEB_01310 3.26e-203 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LNENKMEB_01311 6.59e-227 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LNENKMEB_01312 6.75e-245 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LNENKMEB_01313 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LNENKMEB_01314 1.14e-225 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
LNENKMEB_01315 1.06e-255 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LNENKMEB_01316 3.94e-220 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LNENKMEB_01317 2.31e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LNENKMEB_01318 2.41e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
LNENKMEB_01319 6.95e-203 ykgA - - E - - - Amidinotransferase
LNENKMEB_01320 8.79e-120 ykhA - - I - - - Acyl-CoA hydrolase
LNENKMEB_01321 5.44e-132 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LNENKMEB_01322 4.09e-69 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
LNENKMEB_01323 1.04e-65 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
LNENKMEB_01324 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LNENKMEB_01325 4.35e-262 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LNENKMEB_01326 7.94e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LNENKMEB_01327 6.87e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
LNENKMEB_01328 2.43e-111 ohrR - - K - - - COG1846 Transcriptional regulators
LNENKMEB_01329 1.58e-91 ohrB - - O - - - Organic hydroperoxide resistance protein
LNENKMEB_01330 9.03e-80 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LNENKMEB_01332 1.23e-275 - - - M - - - Glycosyl transferase family 2
LNENKMEB_01333 9.54e-186 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
LNENKMEB_01334 3.41e-278 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LNENKMEB_01335 7.47e-154 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
LNENKMEB_01336 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LNENKMEB_01337 1.74e-224 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LNENKMEB_01338 4.46e-190 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LNENKMEB_01339 1.32e-170 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
LNENKMEB_01340 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_01341 2.31e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
LNENKMEB_01342 3.11e-310 ydhD - - M - - - Glycosyl hydrolase
LNENKMEB_01344 8.66e-310 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
LNENKMEB_01345 1.23e-69 tnrA - - K - - - transcriptional
LNENKMEB_01346 1.11e-23 - - - - - - - -
LNENKMEB_01347 5.25e-37 ykoL - - - - - - -
LNENKMEB_01348 1.98e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
LNENKMEB_01349 3.81e-129 ykoP - - G - - - polysaccharide deacetylase
LNENKMEB_01350 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
LNENKMEB_01351 3.42e-202 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LNENKMEB_01352 1.43e-131 ykoX - - S - - - membrane-associated protein
LNENKMEB_01353 2.05e-173 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LNENKMEB_01354 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LNENKMEB_01355 5.11e-250 ykrI - - S - - - Anti-sigma factor N-terminus
LNENKMEB_01356 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
LNENKMEB_01357 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
LNENKMEB_01358 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LNENKMEB_01359 7.33e-306 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
LNENKMEB_01360 3.5e-147 - - - S - - - Protein of unknown function (DUF421)
LNENKMEB_01361 3.07e-32 ykzE - - - - - - -
LNENKMEB_01362 1.59e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
LNENKMEB_01363 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_01364 2.65e-113 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LNENKMEB_01366 4.44e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LNENKMEB_01367 4.05e-286 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LNENKMEB_01368 1.64e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LNENKMEB_01369 4.42e-292 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LNENKMEB_01370 2.73e-289 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LNENKMEB_01371 9.09e-173 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LNENKMEB_01372 1.11e-147 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LNENKMEB_01373 2.6e-124 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LNENKMEB_01375 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LNENKMEB_01376 1.36e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
LNENKMEB_01377 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LNENKMEB_01378 7.27e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LNENKMEB_01379 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
LNENKMEB_01380 2.69e-232 ykvI - - S - - - membrane
LNENKMEB_01381 3.97e-255 - - - - - - - -
LNENKMEB_01382 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LNENKMEB_01383 8.23e-106 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
LNENKMEB_01384 2.06e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LNENKMEB_01385 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LNENKMEB_01386 1e-79 - - - K - - - HxlR-like helix-turn-helix
LNENKMEB_01387 1.81e-170 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LNENKMEB_01388 2.64e-35 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LNENKMEB_01389 1.67e-269 - - - M - - - Glycosyl transferases group 1
LNENKMEB_01390 3.08e-47 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
LNENKMEB_01391 1.6e-200 - - - G - - - Glycosyl hydrolases family 18
LNENKMEB_01393 7.02e-58 ykvR - - S - - - Protein of unknown function (DUF3219)
LNENKMEB_01394 5.43e-35 ykvS - - S - - - protein conserved in bacteria
LNENKMEB_01395 4.16e-38 - - - - - - - -
LNENKMEB_01396 1.45e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
LNENKMEB_01397 2.66e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LNENKMEB_01398 2.1e-114 stoA - - CO - - - thiol-disulfide
LNENKMEB_01399 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LNENKMEB_01400 6.69e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LNENKMEB_01402 3.37e-223 ykvZ - - K - - - Transcriptional regulator
LNENKMEB_01403 2.29e-198 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
LNENKMEB_01404 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LNENKMEB_01405 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
LNENKMEB_01406 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LNENKMEB_01407 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_01408 1.44e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
LNENKMEB_01409 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LNENKMEB_01410 1.15e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LNENKMEB_01411 1.87e-158 ykwD - - J - - - protein with SCP PR1 domains
LNENKMEB_01412 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LNENKMEB_01413 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_01414 4.65e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LNENKMEB_01415 6.38e-15 - - - - - - - -
LNENKMEB_01416 1.93e-213 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
LNENKMEB_01417 5.07e-108 ykyB - - S - - - YkyB-like protein
LNENKMEB_01418 7.96e-309 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LNENKMEB_01419 5.14e-116 ykuD - - S - - - protein conserved in bacteria
LNENKMEB_01420 6.6e-200 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
LNENKMEB_01421 2.13e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LNENKMEB_01423 7.72e-297 ykuI - - T - - - Diguanylate phosphodiesterase
LNENKMEB_01424 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
LNENKMEB_01425 4.35e-120 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
LNENKMEB_01426 3.09e-35 ykzF - - S - - - Antirepressor AbbA
LNENKMEB_01427 8.55e-99 ykuL - - S - - - CBS domain
LNENKMEB_01428 1.32e-215 ccpC - - K - - - Transcriptional regulator
LNENKMEB_01429 3.15e-117 ykuN - - C ko:K03839 - ko00000 Flavodoxin
LNENKMEB_01430 7.31e-215 ykuO - - - - - - -
LNENKMEB_01431 1.52e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
LNENKMEB_01432 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LNENKMEB_01433 9.73e-277 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LNENKMEB_01434 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
LNENKMEB_01435 6.03e-179 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
LNENKMEB_01436 1.99e-104 ykuV - - CO - - - thiol-disulfide
LNENKMEB_01437 7.46e-127 rok - - K - - - Repressor of ComK
LNENKMEB_01438 2.53e-218 yknT - - - ko:K06437 - ko00000 -
LNENKMEB_01439 4.05e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LNENKMEB_01440 1.71e-241 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LNENKMEB_01441 4.6e-308 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
LNENKMEB_01442 2.64e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
LNENKMEB_01443 2.92e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
LNENKMEB_01444 2.06e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LNENKMEB_01445 4.64e-140 yknW - - S - - - Yip1 domain
LNENKMEB_01446 2e-246 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LNENKMEB_01447 2.9e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_01448 7.01e-268 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
LNENKMEB_01449 5.6e-171 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_01450 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
LNENKMEB_01451 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LNENKMEB_01452 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LNENKMEB_01453 1.82e-50 ykoA - - - - - - -
LNENKMEB_01454 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LNENKMEB_01455 7.27e-206 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LNENKMEB_01456 1.2e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
LNENKMEB_01457 4.47e-18 - - - S - - - Uncharacterized protein YkpC
LNENKMEB_01458 3.72e-235 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
LNENKMEB_01459 6.37e-60 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
LNENKMEB_01460 5.87e-313 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LNENKMEB_01461 5.27e-197 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
LNENKMEB_01462 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LNENKMEB_01463 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LNENKMEB_01464 1.23e-151 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
LNENKMEB_01465 8.3e-66 - - - L - - - transposase activity
LNENKMEB_01466 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LNENKMEB_01467 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
LNENKMEB_01468 7.48e-188 ykrA - - S - - - hydrolases of the HAD superfamily
LNENKMEB_01469 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LNENKMEB_01470 7.91e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LNENKMEB_01471 7.34e-134 ykyA - - L - - - Putative cell-wall binding lipoprotein
LNENKMEB_01472 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LNENKMEB_01473 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LNENKMEB_01474 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
LNENKMEB_01475 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LNENKMEB_01476 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LNENKMEB_01477 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LNENKMEB_01478 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LNENKMEB_01479 0.0 - - - IQ - - - Phosphopantetheine attachment site
LNENKMEB_01480 9.97e-269 - - - V - - - Beta-lactamase
LNENKMEB_01481 7.79e-261 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LNENKMEB_01482 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LNENKMEB_01483 2.96e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LNENKMEB_01484 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LNENKMEB_01485 7.97e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
LNENKMEB_01486 7.14e-186 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
LNENKMEB_01487 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
LNENKMEB_01488 9.4e-57 yktA - - S - - - Belongs to the UPF0223 family
LNENKMEB_01489 4.72e-154 yktB - - S - - - Belongs to the UPF0637 family
LNENKMEB_01490 7.89e-32 ykzI - - - - - - -
LNENKMEB_01491 8.12e-196 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
LNENKMEB_01492 1.3e-108 ykzC - - S - - - Acetyltransferase (GNAT) family
LNENKMEB_01493 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
LNENKMEB_01494 4.16e-236 ylaA - - - - - - -
LNENKMEB_01495 7.37e-59 ylaB - - - - - - -
LNENKMEB_01496 4.7e-120 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LNENKMEB_01498 2.72e-175 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
LNENKMEB_01499 2.48e-69 - - - L - - - COG2963 Transposase and inactivated derivatives
LNENKMEB_01500 6.54e-61 ylaE - - - - - - -
LNENKMEB_01501 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
LNENKMEB_01502 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LNENKMEB_01503 6.99e-65 - - - S - - - YlaH-like protein
LNENKMEB_01504 6.78e-46 ylaI - - S - - - protein conserved in bacteria
LNENKMEB_01505 3.84e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LNENKMEB_01506 9.42e-314 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
LNENKMEB_01507 2.91e-109 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LNENKMEB_01508 6.57e-224 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LNENKMEB_01509 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
LNENKMEB_01510 1.42e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LNENKMEB_01511 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LNENKMEB_01512 3.47e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LNENKMEB_01513 2.95e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LNENKMEB_01514 3.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LNENKMEB_01515 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LNENKMEB_01516 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LNENKMEB_01517 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LNENKMEB_01518 1.03e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
LNENKMEB_01519 1.23e-151 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
LNENKMEB_01520 8.3e-66 - - - L - - - transposase activity
LNENKMEB_01521 1.68e-78 ylbA - - S - - - YugN-like family
LNENKMEB_01522 1.36e-95 ylbB - - T - - - COG0517 FOG CBS domain
LNENKMEB_01523 2.8e-255 ylbC - - S - - - protein with SCP PR1 domains
LNENKMEB_01524 8.47e-87 ylbD - - S - - - Putative coat protein
LNENKMEB_01525 1.73e-48 ylbE - - S - - - YlbE-like protein
LNENKMEB_01526 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
LNENKMEB_01527 2.78e-57 ylbG - - S - - - UPF0298 protein
LNENKMEB_01528 7.68e-116 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
LNENKMEB_01529 1.01e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LNENKMEB_01530 2.91e-277 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
LNENKMEB_01531 1.23e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LNENKMEB_01532 3.07e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LNENKMEB_01533 2.13e-294 ylbM - - S - - - Belongs to the UPF0348 family
LNENKMEB_01534 4.88e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
LNENKMEB_01535 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LNENKMEB_01536 3.13e-111 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LNENKMEB_01537 6.58e-116 ylbP - - K - - - n-acetyltransferase
LNENKMEB_01538 5.87e-211 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LNENKMEB_01539 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LNENKMEB_01540 1.78e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LNENKMEB_01541 4.08e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LNENKMEB_01542 2.4e-68 ftsL - - D - - - Essential cell division protein
LNENKMEB_01543 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LNENKMEB_01544 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
LNENKMEB_01545 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LNENKMEB_01546 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LNENKMEB_01547 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LNENKMEB_01548 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LNENKMEB_01549 1.15e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LNENKMEB_01550 9.58e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
LNENKMEB_01551 3.8e-179 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LNENKMEB_01552 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LNENKMEB_01553 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LNENKMEB_01554 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
LNENKMEB_01555 3.91e-216 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LNENKMEB_01556 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LNENKMEB_01557 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LNENKMEB_01558 1.82e-183 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LNENKMEB_01559 1.56e-315 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
LNENKMEB_01560 7.13e-52 ylmC - - S - - - sporulation protein
LNENKMEB_01561 2.25e-204 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
LNENKMEB_01562 2.59e-161 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LNENKMEB_01563 7.98e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LNENKMEB_01564 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
LNENKMEB_01565 6.85e-179 ylmH - - S - - - conserved protein, contains S4-like domain
LNENKMEB_01566 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
LNENKMEB_01567 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LNENKMEB_01568 8.52e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
LNENKMEB_01569 1.24e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LNENKMEB_01570 3.09e-215 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LNENKMEB_01571 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LNENKMEB_01572 1.39e-296 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
LNENKMEB_01573 3.61e-214 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LNENKMEB_01574 1.28e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LNENKMEB_01575 3.09e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LNENKMEB_01576 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
LNENKMEB_01577 1.01e-180 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LNENKMEB_01578 7.36e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LNENKMEB_01579 5.2e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LNENKMEB_01580 6.31e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LNENKMEB_01582 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
LNENKMEB_01583 8.54e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
LNENKMEB_01584 3.72e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
LNENKMEB_01585 6.76e-143 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
LNENKMEB_01586 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LNENKMEB_01587 8.38e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
LNENKMEB_01588 6.27e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
LNENKMEB_01589 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
LNENKMEB_01590 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
LNENKMEB_01591 3.04e-198 yloC - - S - - - stress-induced protein
LNENKMEB_01592 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
LNENKMEB_01593 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LNENKMEB_01594 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LNENKMEB_01595 2.18e-287 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LNENKMEB_01596 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LNENKMEB_01597 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LNENKMEB_01598 4.76e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LNENKMEB_01599 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LNENKMEB_01600 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LNENKMEB_01601 3.51e-178 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LNENKMEB_01602 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LNENKMEB_01603 6.22e-211 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LNENKMEB_01604 2.81e-149 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LNENKMEB_01605 1.3e-153 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LNENKMEB_01606 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LNENKMEB_01607 3.65e-78 yloU - - S - - - protein conserved in bacteria
LNENKMEB_01608 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
LNENKMEB_01609 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LNENKMEB_01610 4.14e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LNENKMEB_01611 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LNENKMEB_01612 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LNENKMEB_01613 1.81e-228 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LNENKMEB_01614 3.76e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LNENKMEB_01615 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LNENKMEB_01616 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LNENKMEB_01617 6.09e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LNENKMEB_01618 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LNENKMEB_01619 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LNENKMEB_01620 1.44e-180 - - - S - - - Phosphotransferase enzyme family
LNENKMEB_01621 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LNENKMEB_01622 4.92e-302 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LNENKMEB_01623 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LNENKMEB_01624 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LNENKMEB_01625 3.41e-80 ylqD - - S - - - YlqD protein
LNENKMEB_01626 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LNENKMEB_01627 3.42e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LNENKMEB_01628 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LNENKMEB_01629 7.24e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LNENKMEB_01630 3.94e-173 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LNENKMEB_01631 0.0 ylqG - - - - - - -
LNENKMEB_01632 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
LNENKMEB_01633 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LNENKMEB_01634 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LNENKMEB_01635 4.41e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
LNENKMEB_01636 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LNENKMEB_01637 3.83e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LNENKMEB_01638 3.64e-219 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
LNENKMEB_01639 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LNENKMEB_01640 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LNENKMEB_01641 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LNENKMEB_01642 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LNENKMEB_01643 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
LNENKMEB_01644 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
LNENKMEB_01645 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
LNENKMEB_01646 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LNENKMEB_01647 1.32e-120 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
LNENKMEB_01648 1.74e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LNENKMEB_01649 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
LNENKMEB_01650 1.98e-88 ylxF - - S - - - MgtE intracellular N domain
LNENKMEB_01651 4.96e-259 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
LNENKMEB_01652 3.63e-95 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
LNENKMEB_01653 3.26e-178 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
LNENKMEB_01654 7.7e-80 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
LNENKMEB_01655 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LNENKMEB_01656 4.91e-247 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LNENKMEB_01657 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
LNENKMEB_01658 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
LNENKMEB_01659 6.02e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
LNENKMEB_01660 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
LNENKMEB_01661 5.74e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
LNENKMEB_01662 2.53e-242 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LNENKMEB_01663 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LNENKMEB_01664 3.23e-249 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
LNENKMEB_01665 1.05e-198 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
LNENKMEB_01666 3.35e-247 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LNENKMEB_01667 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
LNENKMEB_01668 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
LNENKMEB_01669 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LNENKMEB_01670 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LNENKMEB_01671 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LNENKMEB_01672 1.96e-92 ylxL - - - - - - -
LNENKMEB_01673 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LNENKMEB_01674 4.66e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LNENKMEB_01675 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LNENKMEB_01676 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LNENKMEB_01677 7.76e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LNENKMEB_01678 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LNENKMEB_01679 7.68e-274 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LNENKMEB_01680 9.82e-298 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LNENKMEB_01681 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LNENKMEB_01682 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LNENKMEB_01683 5.66e-106 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LNENKMEB_01684 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LNENKMEB_01685 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
LNENKMEB_01686 6.16e-63 ylxQ - - J - - - ribosomal protein
LNENKMEB_01687 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LNENKMEB_01688 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
LNENKMEB_01689 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LNENKMEB_01690 5.18e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LNENKMEB_01691 2.6e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LNENKMEB_01692 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LNENKMEB_01693 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LNENKMEB_01694 1.02e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
LNENKMEB_01695 2.51e-300 mlpA - - S - - - Belongs to the peptidase M16 family
LNENKMEB_01696 2.17e-56 ymxH - - S - - - YlmC YmxH family
LNENKMEB_01697 1.91e-205 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
LNENKMEB_01698 4.75e-138 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LNENKMEB_01699 1.43e-248 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LNENKMEB_01700 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LNENKMEB_01701 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LNENKMEB_01702 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LNENKMEB_01703 1.31e-165 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
LNENKMEB_01704 3.66e-41 - - - S - - - YlzJ-like protein
LNENKMEB_01705 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LNENKMEB_01706 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_01707 9.04e-296 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LNENKMEB_01708 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LNENKMEB_01709 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
LNENKMEB_01710 3.22e-306 albE - - S - - - Peptidase M16
LNENKMEB_01711 4.79e-309 ymfH - - S - - - zinc protease
LNENKMEB_01712 6.07e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LNENKMEB_01713 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
LNENKMEB_01714 3.82e-184 ymfK - - S - - - Protein of unknown function (DUF3388)
LNENKMEB_01715 5.76e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
LNENKMEB_01716 1.17e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LNENKMEB_01717 9.36e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
LNENKMEB_01718 2.81e-235 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LNENKMEB_01719 3.16e-278 pbpX - - V - - - Beta-lactamase
LNENKMEB_01720 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LNENKMEB_01721 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
LNENKMEB_01722 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
LNENKMEB_01723 1.67e-250 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LNENKMEB_01724 4.29e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LNENKMEB_01725 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LNENKMEB_01726 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
LNENKMEB_01727 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
LNENKMEB_01728 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LNENKMEB_01729 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LNENKMEB_01730 1.96e-49 - - - L - - - Phage integrase family
LNENKMEB_01731 4.62e-49 - - - - - - - -
LNENKMEB_01732 2.47e-59 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
LNENKMEB_01733 6.09e-70 - - - L - - - COG2963 Transposase and inactivated derivatives
LNENKMEB_01734 2.4e-171 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
LNENKMEB_01737 4.05e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
LNENKMEB_01738 4.05e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LNENKMEB_01739 2.5e-231 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
LNENKMEB_01740 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LNENKMEB_01741 2.51e-47 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
LNENKMEB_01742 1.04e-308 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
LNENKMEB_01743 6.15e-187 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
LNENKMEB_01744 1.62e-178 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
LNENKMEB_01745 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
LNENKMEB_01746 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LNENKMEB_01747 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LNENKMEB_01748 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
LNENKMEB_01749 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
LNENKMEB_01750 3.95e-293 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LNENKMEB_01751 6.07e-102 nucB - - M - - - Deoxyribonuclease NucA/NucB
LNENKMEB_01752 1.28e-152 yoaK - - S - - - Membrane
LNENKMEB_01753 1.61e-81 ymzB - - - - - - -
LNENKMEB_01754 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
LNENKMEB_01755 3.03e-06 - - - - - - - -
LNENKMEB_01756 6.85e-164 ymaC - - S - - - Replication protein
LNENKMEB_01757 1.71e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
LNENKMEB_01758 7.46e-72 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LNENKMEB_01759 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LNENKMEB_01761 5.96e-77 ymaF - - S - - - YmaF family
LNENKMEB_01762 7.63e-221 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LNENKMEB_01763 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LNENKMEB_01764 9.98e-58 - - - - - - - -
LNENKMEB_01765 9.42e-29 ymzA - - - - - - -
LNENKMEB_01766 9.34e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
LNENKMEB_01767 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LNENKMEB_01768 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LNENKMEB_01769 2.72e-142 ymaB - - S - - - MutT family
LNENKMEB_01770 1.07e-148 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LNENKMEB_01771 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
LNENKMEB_01772 7.72e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LNENKMEB_01773 4.1e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LNENKMEB_01774 5.34e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
LNENKMEB_01775 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LNENKMEB_01777 8.75e-42 - - - - - - - -
LNENKMEB_01778 7.32e-117 yokH - - G - - - SMI1 / KNR4 family
LNENKMEB_01779 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LNENKMEB_01780 1.5e-65 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LNENKMEB_01781 4.4e-83 yokK - - S - - - SMI1 / KNR4 family
LNENKMEB_01782 1.6e-270 mrjp - - G - - - Major royal jelly protein
LNENKMEB_01783 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
LNENKMEB_01784 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LNENKMEB_01785 7.75e-279 xylR - - GK - - - ROK family
LNENKMEB_01786 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
LNENKMEB_01787 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
LNENKMEB_01788 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
LNENKMEB_01791 1.28e-26 - - - - - - - -
LNENKMEB_01792 5.71e-71 dinB - - S - - - DinB family
LNENKMEB_01793 1.77e-238 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LNENKMEB_01794 1.5e-06 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LNENKMEB_01795 2.79e-182 yoaP - - K - - - YoaP-like
LNENKMEB_01796 1.34e-127 - - - J - - - Acetyltransferase (GNAT) domain
LNENKMEB_01798 3.47e-154 - - - S - - - Domain of unknown function (DUF3885)
LNENKMEB_01799 6.88e-257 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LNENKMEB_01800 1.12e-150 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
LNENKMEB_01801 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LNENKMEB_01802 1.5e-82 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LNENKMEB_01803 1.83e-124 yvgO - - - - - - -
LNENKMEB_01805 0.0 yobO - - M - - - Pectate lyase superfamily protein
LNENKMEB_01806 1.49e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
LNENKMEB_01807 4.99e-185 yndL - - S - - - Replication protein
LNENKMEB_01808 1.74e-11 - - - - - - - -
LNENKMEB_01809 6.29e-185 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
LNENKMEB_01810 3.2e-95 yndM - - S - - - Protein of unknown function (DUF2512)
LNENKMEB_01812 3.18e-141 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LNENKMEB_01813 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LNENKMEB_01814 4.29e-144 yneB - - L - - - resolvase
LNENKMEB_01815 2.33e-43 ynzC - - S - - - UPF0291 protein
LNENKMEB_01816 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LNENKMEB_01817 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
LNENKMEB_01818 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
LNENKMEB_01819 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
LNENKMEB_01820 4.47e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
LNENKMEB_01821 7.09e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
LNENKMEB_01822 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
LNENKMEB_01823 1.18e-98 yneK - - S - - - Protein of unknown function (DUF2621)
LNENKMEB_01824 2.44e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
LNENKMEB_01825 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
LNENKMEB_01826 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
LNENKMEB_01827 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LNENKMEB_01828 3.46e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LNENKMEB_01830 1e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
LNENKMEB_01831 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
LNENKMEB_01832 2.23e-69 yneQ - - - - - - -
LNENKMEB_01833 2.67e-66 yneR - - S - - - Belongs to the HesB IscA family
LNENKMEB_01834 9.09e-121 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LNENKMEB_01835 5.75e-89 yneT - - S ko:K06929 - ko00000 CoA-binding protein
LNENKMEB_01836 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LNENKMEB_01837 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LNENKMEB_01838 2.21e-19 - - - - - - - -
LNENKMEB_01839 1.82e-63 ynfC - - - - - - -
LNENKMEB_01840 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LNENKMEB_01841 2.49e-228 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
LNENKMEB_01842 4.91e-241 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
LNENKMEB_01843 1.84e-147 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
LNENKMEB_01844 7.99e-271 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
LNENKMEB_01845 7.45e-194 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LNENKMEB_01846 2.14e-232 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
LNENKMEB_01847 3.21e-286 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
LNENKMEB_01848 6.47e-205 yndG - - S - - - DoxX-like family
LNENKMEB_01849 1.11e-99 - - - S - - - Domain of unknown function (DUF4166)
LNENKMEB_01850 0.0 yndJ - - S - - - YndJ-like protein
LNENKMEB_01852 2.99e-34 - - - - - - - -
LNENKMEB_01854 8.12e-138 - - - S - - - COG0457 FOG TPR repeat
LNENKMEB_01859 1.86e-96 - - - S ko:K02004 - ko00000,ko00002,ko02000 bacteriocin-associated integral membrane protein
LNENKMEB_01860 7.04e-83 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LNENKMEB_01863 1.65e-257 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
LNENKMEB_01864 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
LNENKMEB_01865 3.64e-70 yvlA - - S - - - Domain of unknown function (DUF4870)
LNENKMEB_01866 3.42e-312 - - - T - - - Histidine kinase
LNENKMEB_01867 1.32e-164 - - - T - - - Transcriptional regulatory protein, C terminal
LNENKMEB_01868 0.0 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
LNENKMEB_01869 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LNENKMEB_01870 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LNENKMEB_01871 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LNENKMEB_01872 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LNENKMEB_01873 6.93e-281 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LNENKMEB_01874 2.37e-177 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LNENKMEB_01875 4.5e-157 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LNENKMEB_01876 1.48e-160 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LNENKMEB_01877 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
LNENKMEB_01878 3.58e-282 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LNENKMEB_01879 1.94e-247 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LNENKMEB_01880 6.12e-166 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LNENKMEB_01881 3.25e-272 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LNENKMEB_01882 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LNENKMEB_01883 9.44e-186 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LNENKMEB_01884 9.19e-90 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LNENKMEB_01885 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
LNENKMEB_01886 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LNENKMEB_01887 8.28e-177 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
LNENKMEB_01888 6.01e-215 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
LNENKMEB_01889 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
LNENKMEB_01890 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
LNENKMEB_01891 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LNENKMEB_01892 5.35e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LNENKMEB_01893 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
LNENKMEB_01894 1.67e-85 yngL - - S - - - Protein of unknown function (DUF1360)
LNENKMEB_01895 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
LNENKMEB_01896 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LNENKMEB_01897 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LNENKMEB_01898 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LNENKMEB_01899 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LNENKMEB_01900 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LNENKMEB_01901 1.93e-239 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LNENKMEB_01902 3.69e-312 yoeA - - V - - - MATE efflux family protein
LNENKMEB_01903 4.47e-126 yoeB - - S - - - IseA DL-endopeptidase inhibitor
LNENKMEB_01904 9.32e-179 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
LNENKMEB_01905 4.06e-59 - - - - - - - -
LNENKMEB_01907 1.67e-86 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
LNENKMEB_01908 5.36e-84 - - - S - - - Pfam:Phage_holin_4_1
LNENKMEB_01911 2.06e-232 - - - S - - - Domain of unknown function (DUF2479)
LNENKMEB_01912 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
LNENKMEB_01913 4.86e-290 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
LNENKMEB_01914 9.28e-140 - - - S - - - Phage tail protein
LNENKMEB_01915 0.0 - - - S - - - peptidoglycan catabolic process
LNENKMEB_01916 5.09e-16 - - - - - - - -
LNENKMEB_01917 4.7e-31 - - - - - - - -
LNENKMEB_01918 3.11e-77 - - - - - - - -
LNENKMEB_01919 3.5e-41 - - - - - - - -
LNENKMEB_01920 2.28e-64 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LNENKMEB_01921 8.76e-20 - - - S - - - Phage head-tail joining protein
LNENKMEB_01922 8.64e-33 - - - S - - - Phage gp6-like head-tail connector protein
LNENKMEB_01923 1.02e-60 - - - S - - - peptidoglycan catabolic process
LNENKMEB_01924 5.61e-08 - - - S - - - peptidoglycan catabolic process
LNENKMEB_01925 2.81e-226 - - - S - - - capsid protein
LNENKMEB_01926 2.32e-144 - - - S - - - peptidase activity
LNENKMEB_01927 6.25e-308 - - - S - - - Phage portal protein
LNENKMEB_01928 1.56e-14 - - - - - - - -
LNENKMEB_01929 4.53e-290 - - - S - - - Phage Terminase
LNENKMEB_01930 3.5e-90 - - - S - - - Phage terminase, small subunit
LNENKMEB_01932 9.91e-87 - - - S - - - HNH endonuclease
LNENKMEB_01937 1.07e-92 - - - L - - - Phage integrase family
LNENKMEB_01938 5.82e-70 - - - M - - - ArpU family transcriptional regulator
LNENKMEB_01939 1.16e-56 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LNENKMEB_01941 1.38e-66 - - - S - - - dUTPase
LNENKMEB_01946 4.55e-21 yqaO - - S - - - Phage-like element PBSX protein XtrA
LNENKMEB_01947 1.09e-05 - - - - - - - -
LNENKMEB_01949 2.97e-36 - - - - - - - -
LNENKMEB_01950 1.46e-08 - - - - - - - -
LNENKMEB_01953 8.14e-116 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
LNENKMEB_01955 6.41e-50 - - - S - - - Domain of unknown function (DUF771)
LNENKMEB_01956 8.18e-07 ahdIC - - K - - - PFAM helix-turn-helix domain protein
LNENKMEB_01957 3.44e-38 - - - K - - - Helix-turn-helix XRE-family like proteins
LNENKMEB_01960 3.49e-91 - - - - - - - -
LNENKMEB_01961 1.62e-147 - - - L - - - Phage integrase family
LNENKMEB_01963 1.14e-124 - - - L - - - Integrase
LNENKMEB_01964 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
LNENKMEB_01965 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LNENKMEB_01966 1.13e-254 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
LNENKMEB_01967 3.29e-67 - - - K - - - Helix-turn-helix domain
LNENKMEB_01968 3.63e-16 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LNENKMEB_01969 1.51e-200 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_01970 3.07e-240 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LNENKMEB_01971 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LNENKMEB_01972 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
LNENKMEB_01973 3.04e-204 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_01974 5.68e-259 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LNENKMEB_01975 7.2e-183 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LNENKMEB_01976 8.13e-82 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LNENKMEB_01977 3.49e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LNENKMEB_01978 6.9e-56 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LNENKMEB_01979 3.14e-178 yoxB - - - - - - -
LNENKMEB_01980 7.72e-262 yoaB - - EGP - - - the major facilitator superfamily
LNENKMEB_01981 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
LNENKMEB_01982 8.91e-248 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LNENKMEB_01983 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LNENKMEB_01985 1.56e-126 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LNENKMEB_01986 1.99e-58 - - - - - - - -
LNENKMEB_01987 2.94e-251 - - - L - - - COG3666 Transposase and inactivated derivatives
LNENKMEB_01988 4.34e-99 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LNENKMEB_01989 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LNENKMEB_01990 1.49e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
LNENKMEB_01991 6.14e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
LNENKMEB_01992 2.34e-120 yobS - - K - - - Transcriptional regulator
LNENKMEB_01993 6.63e-173 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LNENKMEB_01994 3.86e-119 yobW - - - - - - -
LNENKMEB_01995 7.69e-73 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
LNENKMEB_01996 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LNENKMEB_01997 1.33e-117 yozB - - S ko:K08976 - ko00000 membrane
LNENKMEB_01998 2.69e-183 - - - J - - - Protein required for attachment to host cells
LNENKMEB_01999 2.27e-123 yocC - - - - - - -
LNENKMEB_02000 1.58e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
LNENKMEB_02002 9.79e-168 yocH - - M - - - COG1388 FOG LysM repeat
LNENKMEB_02003 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LNENKMEB_02004 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LNENKMEB_02006 4.5e-79 yocK - - T - - - general stress protein
LNENKMEB_02007 2.71e-13 yocL - - - - - - -
LNENKMEB_02008 3.51e-13 yocN - - - - - - -
LNENKMEB_02009 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LNENKMEB_02010 5.58e-59 yozN - - - - - - -
LNENKMEB_02011 1.83e-49 yocN - - - - - - -
LNENKMEB_02012 5.32e-75 yozO - - S - - - Bacterial PH domain
LNENKMEB_02014 4.69e-43 yozC - - - - - - -
LNENKMEB_02015 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LNENKMEB_02016 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
LNENKMEB_02017 4.76e-212 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
LNENKMEB_02018 1.45e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LNENKMEB_02019 9.85e-215 yocS - - S ko:K03453 - ko00000 -transporter
LNENKMEB_02020 3.16e-180 - - - S - - - Metallo-beta-lactamase superfamily
LNENKMEB_02021 2.47e-261 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LNENKMEB_02022 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LNENKMEB_02023 0.0 yojO - - P - - - Von Willebrand factor
LNENKMEB_02024 3.45e-208 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
LNENKMEB_02025 2.65e-144 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LNENKMEB_02026 6.08e-293 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LNENKMEB_02027 2.01e-286 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
LNENKMEB_02028 9.47e-144 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LNENKMEB_02030 4.62e-308 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
LNENKMEB_02031 1.44e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LNENKMEB_02032 1.57e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
LNENKMEB_02033 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
LNENKMEB_02034 1.05e-30 - - - - - - - -
LNENKMEB_02035 8.49e-210 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
LNENKMEB_02036 1.15e-104 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
LNENKMEB_02038 4.29e-88 iolK - - S - - - tautomerase
LNENKMEB_02039 2.74e-92 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
LNENKMEB_02040 1.2e-74 yodB - - K - - - transcriptional
LNENKMEB_02041 1.35e-138 yodC - - C - - - nitroreductase
LNENKMEB_02042 4.37e-143 yahD - - S ko:K06999 - ko00000 Carboxylesterase
LNENKMEB_02043 1.8e-220 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LNENKMEB_02044 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
LNENKMEB_02045 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LNENKMEB_02046 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
LNENKMEB_02047 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LNENKMEB_02048 1.23e-169 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_02049 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LNENKMEB_02050 1.76e-165 yodH - - Q - - - Methyltransferase
LNENKMEB_02051 6.87e-50 yodI - - - - - - -
LNENKMEB_02052 7.76e-193 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
LNENKMEB_02053 4.29e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
LNENKMEB_02055 1.16e-72 yodL - - S - - - YodL-like
LNENKMEB_02056 1.83e-134 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LNENKMEB_02057 9.77e-34 yozD - - S - - - YozD-like protein
LNENKMEB_02059 1.9e-161 yodN - - - - - - -
LNENKMEB_02060 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
LNENKMEB_02061 8.43e-64 yokU - - S - - - YokU-like protein, putative antitoxin
LNENKMEB_02062 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
LNENKMEB_02063 1.71e-204 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
LNENKMEB_02064 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
LNENKMEB_02065 1.55e-158 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LNENKMEB_02066 6.87e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LNENKMEB_02067 2.06e-313 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LNENKMEB_02068 2.39e-83 - - - L - - - Bacterial transcription activator, effector binding domain
LNENKMEB_02070 4.02e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
LNENKMEB_02071 1.97e-316 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
LNENKMEB_02072 3.32e-62 cgeC - - - ko:K06321 - ko00000 -
LNENKMEB_02073 1.55e-90 cgeA - - - ko:K06319 - ko00000 -
LNENKMEB_02074 1.56e-231 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
LNENKMEB_02075 9.09e-282 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
LNENKMEB_02076 3.54e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LNENKMEB_02081 1.11e-100 yoqH - - M - - - LysM domain
LNENKMEB_02082 7.33e-250 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LNENKMEB_02084 4.15e-217 - - - S - - - amine dehydrogenase activity
LNENKMEB_02087 3.08e-81 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LNENKMEB_02088 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LNENKMEB_02089 6.3e-111 - - - G - - - SMI1-KNR4 cell-wall
LNENKMEB_02090 2.08e-108 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
LNENKMEB_02091 0.0 yokA - - L - - - Recombinase
LNENKMEB_02092 1.02e-135 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LNENKMEB_02093 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LNENKMEB_02094 1.2e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LNENKMEB_02095 8.22e-90 ypoP - - K - - - transcriptional
LNENKMEB_02096 3.78e-124 ypmS - - S - - - protein conserved in bacteria
LNENKMEB_02097 2.12e-175 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
LNENKMEB_02098 3.32e-148 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LNENKMEB_02099 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
LNENKMEB_02100 4.25e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LNENKMEB_02101 1.05e-226 yplP - - K - - - Transcriptional regulator
LNENKMEB_02102 7.44e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
LNENKMEB_02103 7.27e-252 - - - L - - - COG3666 Transposase and inactivated derivatives
LNENKMEB_02104 6.7e-148 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LNENKMEB_02105 2.89e-115 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LNENKMEB_02106 6.22e-204 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LNENKMEB_02107 6.48e-148 ypjP - - S - - - YpjP-like protein
LNENKMEB_02108 3.49e-172 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
LNENKMEB_02109 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
LNENKMEB_02110 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
LNENKMEB_02111 1.15e-203 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
LNENKMEB_02112 1.33e-127 yagB - - S ko:K06950 - ko00000 phosphohydrolase
LNENKMEB_02113 1.13e-112 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
LNENKMEB_02114 1.89e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LNENKMEB_02115 5.21e-275 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LNENKMEB_02116 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
LNENKMEB_02117 1.27e-17 degR - - - - - - -
LNENKMEB_02118 1.13e-49 - - - S - - - Protein of unknown function (DUF2564)
LNENKMEB_02119 3.15e-38 ypeQ - - S - - - Zinc-finger
LNENKMEB_02120 2.06e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
LNENKMEB_02121 9.33e-153 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LNENKMEB_02122 2.11e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
LNENKMEB_02124 1.93e-209 ypcP - - L - - - 5'3' exonuclease
LNENKMEB_02125 2.44e-10 - - - - - - - -
LNENKMEB_02126 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
LNENKMEB_02127 0.0 ypbR - - S - - - Dynamin family
LNENKMEB_02128 1.26e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
LNENKMEB_02129 1.53e-269 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
LNENKMEB_02130 1.07e-137 - - - J - - - Acetyltransferase (GNAT) domain
LNENKMEB_02131 2.21e-66 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
LNENKMEB_02132 1.21e-08 - - - S - - - Bacillus cereus group antimicrobial protein
LNENKMEB_02133 1.07e-43 ydfR - - S - - - Protein of unknown function (DUF421)
LNENKMEB_02134 5.38e-44 ydfR - - S - - - Protein of unknown function (DUF421)
LNENKMEB_02135 3.64e-129 yrdC - - Q - - - Isochorismatase family
LNENKMEB_02136 2.23e-07 - - - S - - - Bacillus cereus group antimicrobial protein
LNENKMEB_02137 5.07e-298 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
LNENKMEB_02138 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LNENKMEB_02139 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LNENKMEB_02140 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
LNENKMEB_02142 6.91e-31 - - - S - - - YpzG-like protein
LNENKMEB_02143 4.68e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LNENKMEB_02144 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LNENKMEB_02145 1.33e-128 ypsA - - S - - - Belongs to the UPF0398 family
LNENKMEB_02146 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
LNENKMEB_02148 1.83e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
LNENKMEB_02149 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LNENKMEB_02150 1.21e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
LNENKMEB_02151 5.09e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LNENKMEB_02152 1.72e-83 yppG - - S - - - YppG-like protein
LNENKMEB_02156 0.000542 - - - - ko:K06430 - ko00000 -
LNENKMEB_02157 3.32e-238 yppC - - S - - - Protein of unknown function (DUF2515)
LNENKMEB_02158 1.47e-144 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LNENKMEB_02159 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LNENKMEB_02160 4.98e-117 ypoC - - - - - - -
LNENKMEB_02161 1.02e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LNENKMEB_02162 2.81e-166 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
LNENKMEB_02163 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
LNENKMEB_02164 4.01e-281 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LNENKMEB_02165 9.65e-105 ypmB - - S - - - protein conserved in bacteria
LNENKMEB_02166 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
LNENKMEB_02167 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LNENKMEB_02168 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LNENKMEB_02169 1.15e-201 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LNENKMEB_02170 1.14e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LNENKMEB_02171 3.67e-229 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LNENKMEB_02172 6.9e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LNENKMEB_02173 3.63e-269 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
LNENKMEB_02174 1.23e-167 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
LNENKMEB_02175 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
LNENKMEB_02176 9.78e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LNENKMEB_02177 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
LNENKMEB_02178 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LNENKMEB_02179 2.01e-289 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LNENKMEB_02180 2.05e-182 ypjB - - S - - - sporulation protein
LNENKMEB_02181 9.19e-137 ypjA - - S - - - membrane
LNENKMEB_02182 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
LNENKMEB_02183 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
LNENKMEB_02184 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
LNENKMEB_02185 5.77e-102 ypiF - - S - - - Protein of unknown function (DUF2487)
LNENKMEB_02186 1.06e-128 ypiB - - S - - - Belongs to the UPF0302 family
LNENKMEB_02187 7.49e-299 ypiA - - S - - - COG0457 FOG TPR repeat
LNENKMEB_02188 4.03e-301 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LNENKMEB_02189 1.52e-261 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
LNENKMEB_02190 6.13e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LNENKMEB_02191 2.8e-187 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LNENKMEB_02192 6.04e-291 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LNENKMEB_02193 9.06e-151 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
LNENKMEB_02194 4.97e-169 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
LNENKMEB_02195 5.82e-212 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LNENKMEB_02196 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LNENKMEB_02197 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LNENKMEB_02198 7.79e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LNENKMEB_02199 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LNENKMEB_02200 3.54e-181 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
LNENKMEB_02201 2.35e-101 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LNENKMEB_02202 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LNENKMEB_02203 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LNENKMEB_02204 3.96e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LNENKMEB_02205 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LNENKMEB_02206 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
LNENKMEB_02207 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LNENKMEB_02208 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LNENKMEB_02209 5.64e-172 yphF - - - - - - -
LNENKMEB_02210 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
LNENKMEB_02211 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LNENKMEB_02212 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LNENKMEB_02213 3.58e-135 yphA - - - - - - -
LNENKMEB_02214 1.87e-12 - - - S - - - YpzI-like protein
LNENKMEB_02215 1.02e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LNENKMEB_02216 8.14e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LNENKMEB_02217 2.87e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LNENKMEB_02218 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
LNENKMEB_02219 2.02e-78 ypfA - - M - - - Flagellar protein YcgR
LNENKMEB_02220 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
LNENKMEB_02221 3.77e-213 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
LNENKMEB_02222 6.4e-156 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
LNENKMEB_02223 1.07e-238 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
LNENKMEB_02224 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LNENKMEB_02225 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LNENKMEB_02226 1.4e-190 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
LNENKMEB_02227 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
LNENKMEB_02228 3.55e-133 ypbE - - M - - - Lysin motif
LNENKMEB_02229 1.09e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
LNENKMEB_02230 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LNENKMEB_02231 1.05e-253 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
LNENKMEB_02232 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
LNENKMEB_02233 6.2e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LNENKMEB_02234 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LNENKMEB_02235 2.02e-249 rsiX - - - - - - -
LNENKMEB_02236 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LNENKMEB_02237 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_02238 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LNENKMEB_02239 1.26e-251 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LNENKMEB_02240 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
LNENKMEB_02241 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LNENKMEB_02242 7.38e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LNENKMEB_02243 3.66e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
LNENKMEB_02244 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
LNENKMEB_02245 2.57e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LNENKMEB_02246 5.05e-121 ypuI - - S - - - Protein of unknown function (DUF3907)
LNENKMEB_02247 2.73e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LNENKMEB_02248 4.93e-165 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LNENKMEB_02250 5.71e-121 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
LNENKMEB_02251 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LNENKMEB_02252 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LNENKMEB_02253 1.8e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LNENKMEB_02254 2.2e-141 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
LNENKMEB_02255 5.34e-268 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LNENKMEB_02256 4.92e-71 ypuD - - - - - - -
LNENKMEB_02257 3.8e-130 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LNENKMEB_02258 1.36e-105 ccdC1 - - O - - - Protein of unknown function (DUF1453)
LNENKMEB_02259 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LNENKMEB_02260 6.31e-199 ypuA - - S - - - Secreted protein
LNENKMEB_02261 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LNENKMEB_02262 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
LNENKMEB_02263 1.31e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
LNENKMEB_02264 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
LNENKMEB_02265 8.19e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
LNENKMEB_02266 9.92e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
LNENKMEB_02267 1.43e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
LNENKMEB_02268 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
LNENKMEB_02269 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LNENKMEB_02270 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LNENKMEB_02271 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
LNENKMEB_02272 1.74e-273 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LNENKMEB_02273 9.06e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LNENKMEB_02274 4.97e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
LNENKMEB_02275 2.17e-211 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
LNENKMEB_02276 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
LNENKMEB_02277 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LNENKMEB_02278 2.04e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LNENKMEB_02279 1.93e-38 yqkK - - - - - - -
LNENKMEB_02280 1.96e-30 - - - - - - - -
LNENKMEB_02281 8.31e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LNENKMEB_02282 5.89e-312 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LNENKMEB_02283 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
LNENKMEB_02284 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
LNENKMEB_02285 1.15e-75 ansR - - K - - - Transcriptional regulator
LNENKMEB_02286 1.39e-278 yqxK - - L - - - DNA helicase
LNENKMEB_02287 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
LNENKMEB_02288 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
LNENKMEB_02289 2.18e-216 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
LNENKMEB_02290 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
LNENKMEB_02291 1.73e-227 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LNENKMEB_02292 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
LNENKMEB_02293 5.4e-80 yqkB - - S - - - Belongs to the HesB IscA family
LNENKMEB_02294 1.44e-223 yqkA - - K - - - GrpB protein
LNENKMEB_02295 1.71e-80 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
LNENKMEB_02296 2.81e-115 yqjY - - K ko:K06977 - ko00000 acetyltransferase
LNENKMEB_02297 1.15e-299 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LNENKMEB_02298 9.19e-76 - - - S - - - YolD-like protein
LNENKMEB_02300 6.44e-243 yueF - - S - - - transporter activity
LNENKMEB_02302 2.67e-96 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LNENKMEB_02303 4.46e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LNENKMEB_02304 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
LNENKMEB_02305 3.39e-180 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LNENKMEB_02306 6.83e-224 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LNENKMEB_02307 2.76e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LNENKMEB_02308 1.68e-175 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
LNENKMEB_02309 7.87e-306 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
LNENKMEB_02310 4e-281 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LNENKMEB_02311 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LNENKMEB_02312 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LNENKMEB_02313 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LNENKMEB_02314 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LNENKMEB_02315 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LNENKMEB_02316 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LNENKMEB_02317 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LNENKMEB_02318 2.78e-168 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LNENKMEB_02319 5.63e-316 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LNENKMEB_02322 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LNENKMEB_02323 6.14e-122 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LNENKMEB_02324 1.73e-42 - - - S - - - GlpM protein
LNENKMEB_02325 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LNENKMEB_02326 2.72e-190 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LNENKMEB_02327 2.1e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LNENKMEB_02328 2.66e-218 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LNENKMEB_02329 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LNENKMEB_02330 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LNENKMEB_02331 3.31e-302 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LNENKMEB_02332 1.3e-34 yqzJ - - - - - - -
LNENKMEB_02333 2.05e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LNENKMEB_02334 8.71e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
LNENKMEB_02335 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LNENKMEB_02336 7.7e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
LNENKMEB_02338 2.61e-123 yqjB - - S - - - protein conserved in bacteria
LNENKMEB_02339 1.6e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
LNENKMEB_02340 2.58e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LNENKMEB_02341 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LNENKMEB_02342 5.83e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LNENKMEB_02343 4.83e-99 yqiW - - S - - - Belongs to the UPF0403 family
LNENKMEB_02344 9.62e-216 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LNENKMEB_02345 5.1e-284 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LNENKMEB_02346 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LNENKMEB_02347 7.89e-222 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LNENKMEB_02348 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LNENKMEB_02349 6.96e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
LNENKMEB_02350 1.58e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LNENKMEB_02351 9.65e-195 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
LNENKMEB_02352 0.0 bkdR - - KT - - - Transcriptional regulator
LNENKMEB_02353 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
LNENKMEB_02354 4e-205 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LNENKMEB_02355 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
LNENKMEB_02356 7.23e-263 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LNENKMEB_02357 1.51e-261 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
LNENKMEB_02358 2.41e-197 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
LNENKMEB_02359 5.6e-272 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LNENKMEB_02360 3.83e-175 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LNENKMEB_02361 1.39e-136 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
LNENKMEB_02363 1.13e-130 - - - P - - - Probably functions as a manganese efflux pump
LNENKMEB_02364 6.93e-147 - - - K - - - Protein of unknown function (DUF1232)
LNENKMEB_02366 9.67e-274 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LNENKMEB_02369 5.23e-277 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LNENKMEB_02370 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LNENKMEB_02371 5.12e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
LNENKMEB_02372 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LNENKMEB_02373 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LNENKMEB_02374 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
LNENKMEB_02375 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LNENKMEB_02376 1.11e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LNENKMEB_02377 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LNENKMEB_02378 4.1e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LNENKMEB_02379 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LNENKMEB_02380 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LNENKMEB_02381 1.36e-87 yqhY - - S - - - protein conserved in bacteria
LNENKMEB_02382 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LNENKMEB_02383 2.32e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LNENKMEB_02384 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
LNENKMEB_02385 2.86e-149 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
LNENKMEB_02386 1.05e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
LNENKMEB_02387 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
LNENKMEB_02388 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
LNENKMEB_02389 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
LNENKMEB_02390 1.4e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
LNENKMEB_02391 1.04e-219 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
LNENKMEB_02392 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
LNENKMEB_02393 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LNENKMEB_02394 6.04e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LNENKMEB_02395 3.99e-118 yqhR - - S - - - Conserved membrane protein YqhR
LNENKMEB_02396 1.04e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
LNENKMEB_02397 7.65e-83 yqhP - - - - - - -
LNENKMEB_02398 9.94e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LNENKMEB_02399 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LNENKMEB_02400 1.58e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LNENKMEB_02401 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
LNENKMEB_02402 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LNENKMEB_02403 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LNENKMEB_02404 9.52e-264 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
LNENKMEB_02405 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LNENKMEB_02406 3.57e-194 yqhG - - S - - - Bacterial protein YqhG of unknown function
LNENKMEB_02407 2.31e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
LNENKMEB_02408 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
LNENKMEB_02409 1.82e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
LNENKMEB_02410 3.13e-101 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
LNENKMEB_02411 4.47e-154 yqxM - - - ko:K19433 - ko00000 -
LNENKMEB_02412 6.88e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
LNENKMEB_02413 2e-36 yqzE - - S - - - YqzE-like protein
LNENKMEB_02414 4.9e-83 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
LNENKMEB_02415 1.34e-86 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
LNENKMEB_02416 6.31e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
LNENKMEB_02417 6.79e-95 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
LNENKMEB_02418 1.82e-65 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
LNENKMEB_02419 1.89e-232 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
LNENKMEB_02420 3.84e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LNENKMEB_02421 6.43e-239 yqxL - - P - - - Mg2 transporter protein
LNENKMEB_02422 6.5e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LNENKMEB_02423 1.44e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LNENKMEB_02425 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
LNENKMEB_02426 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
LNENKMEB_02427 2e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
LNENKMEB_02428 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
LNENKMEB_02429 2.99e-65 dglA - - S - - - Thiamine-binding protein
LNENKMEB_02430 7.35e-254 yqgU - - - - - - -
LNENKMEB_02431 9.8e-282 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
LNENKMEB_02432 2.91e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LNENKMEB_02433 1.3e-301 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LNENKMEB_02434 1.88e-11 yqgO - - - - - - -
LNENKMEB_02435 3.51e-125 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LNENKMEB_02436 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LNENKMEB_02437 3.42e-68 yqzD - - - - - - -
LNENKMEB_02438 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LNENKMEB_02439 2.32e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LNENKMEB_02440 1.75e-187 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LNENKMEB_02441 2.39e-198 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
LNENKMEB_02442 3.53e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LNENKMEB_02443 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LNENKMEB_02444 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
LNENKMEB_02445 2.37e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
LNENKMEB_02446 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
LNENKMEB_02447 6.78e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
LNENKMEB_02448 1.08e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
LNENKMEB_02449 3.05e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
LNENKMEB_02450 2.3e-255 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LNENKMEB_02451 3.34e-80 yqfX - - S - - - membrane
LNENKMEB_02452 2.88e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
LNENKMEB_02453 2.25e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
LNENKMEB_02454 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LNENKMEB_02455 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
LNENKMEB_02456 7.01e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LNENKMEB_02457 6.06e-308 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LNENKMEB_02458 3.93e-87 yqfQ - - S - - - YqfQ-like protein
LNENKMEB_02459 3.53e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LNENKMEB_02460 2.48e-69 - - - L - - - COG2963 Transposase and inactivated derivatives
LNENKMEB_02461 2.72e-175 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
LNENKMEB_02462 3.1e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LNENKMEB_02463 7e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LNENKMEB_02464 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LNENKMEB_02465 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LNENKMEB_02466 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LNENKMEB_02467 1.36e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
LNENKMEB_02468 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LNENKMEB_02469 5.89e-145 ccpN - - K - - - CBS domain
LNENKMEB_02470 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LNENKMEB_02471 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LNENKMEB_02472 8.73e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LNENKMEB_02473 6e-24 - - - S - - - YqzL-like protein
LNENKMEB_02474 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LNENKMEB_02475 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LNENKMEB_02476 1.51e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LNENKMEB_02477 7.14e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LNENKMEB_02478 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
LNENKMEB_02479 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
LNENKMEB_02480 1.3e-282 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
LNENKMEB_02481 3.57e-61 yqfC - - S - - - sporulation protein YqfC
LNENKMEB_02482 1.04e-84 yqfB - - - - - - -
LNENKMEB_02483 4.48e-189 yqfA - - S - - - UPF0365 protein
LNENKMEB_02484 2.7e-295 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
LNENKMEB_02485 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
LNENKMEB_02486 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LNENKMEB_02487 3.23e-200 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
LNENKMEB_02488 2.04e-66 - - - L - - - transposase activity
LNENKMEB_02489 1.23e-151 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
LNENKMEB_02490 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
LNENKMEB_02491 1.18e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LNENKMEB_02492 2.68e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
LNENKMEB_02493 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LNENKMEB_02494 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LNENKMEB_02495 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LNENKMEB_02496 2.73e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LNENKMEB_02497 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
LNENKMEB_02498 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LNENKMEB_02499 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
LNENKMEB_02500 9.09e-280 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
LNENKMEB_02501 2.51e-260 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LNENKMEB_02502 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LNENKMEB_02503 3.68e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LNENKMEB_02504 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LNENKMEB_02505 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
LNENKMEB_02506 2.06e-136 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
LNENKMEB_02507 8.04e-191 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LNENKMEB_02508 8.39e-179 yqeM - - Q - - - Methyltransferase
LNENKMEB_02509 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LNENKMEB_02510 2.38e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
LNENKMEB_02511 2.89e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LNENKMEB_02512 3.12e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
LNENKMEB_02513 9.86e-200 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LNENKMEB_02514 7.93e-272 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LNENKMEB_02515 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
LNENKMEB_02517 1.03e-177 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
LNENKMEB_02518 8.09e-181 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
LNENKMEB_02519 2.92e-138 yqeD - - S - - - SNARE associated Golgi protein
LNENKMEB_02520 4.51e-47 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LNENKMEB_02521 1.82e-276 - - - EGP - - - Transmembrane secretion effector
LNENKMEB_02522 5.58e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LNENKMEB_02523 2.74e-33 xkdS - - S - - - Protein of unknown function (DUF2634)
LNENKMEB_02524 4.64e-140 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LNENKMEB_02525 3.94e-27 xkdR - - S - - - Protein of unknown function (DUF2577)
LNENKMEB_02527 2.03e-173 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Reductase
LNENKMEB_02528 2.72e-91 - - - K - - - MerR family transcriptional regulator
LNENKMEB_02529 2.4e-20 xkdG - - S - - - Phage capsid family
LNENKMEB_02530 3.89e-206 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
LNENKMEB_02531 9.84e-123 - - - K - - - Transcriptional regulator PadR-like family
LNENKMEB_02532 2.15e-90 psiE - - S ko:K13256 - ko00000 Belongs to the PsiE family
LNENKMEB_02533 1.09e-307 yrkQ - - T - - - Histidine kinase
LNENKMEB_02534 3.26e-160 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
LNENKMEB_02535 1.28e-274 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
LNENKMEB_02536 1.76e-130 yrkN - - K - - - Acetyltransferase (GNAT) family
LNENKMEB_02537 2.23e-129 yqaC - - F - - - adenylate kinase activity
LNENKMEB_02538 2.13e-40 - - - K - - - acetyltransferase
LNENKMEB_02539 7.59e-280 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
LNENKMEB_02540 2.89e-103 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
LNENKMEB_02541 6.77e-121 - - - S - - - DinB family
LNENKMEB_02542 1.69e-189 supH - - S - - - hydrolase
LNENKMEB_02543 1.23e-173 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
LNENKMEB_02544 5.86e-168 - - - K - - - Helix-turn-helix domain, rpiR family
LNENKMEB_02545 2.95e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LNENKMEB_02546 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LNENKMEB_02547 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
LNENKMEB_02548 5.44e-230 romA - - S - - - Beta-lactamase superfamily domain
LNENKMEB_02549 4.62e-107 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LNENKMEB_02550 2.17e-210 yybE - - K - - - Transcriptional regulator
LNENKMEB_02551 7.6e-270 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LNENKMEB_02552 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LNENKMEB_02553 3.36e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
LNENKMEB_02554 9.01e-121 yrhH - - Q - - - methyltransferase
LNENKMEB_02555 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
LNENKMEB_02556 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
LNENKMEB_02557 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
LNENKMEB_02558 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
LNENKMEB_02559 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
LNENKMEB_02560 3.31e-47 yrhC - - S - - - YrhC-like protein
LNENKMEB_02561 5.35e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LNENKMEB_02562 2.28e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
LNENKMEB_02563 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LNENKMEB_02564 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
LNENKMEB_02565 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
LNENKMEB_02566 8.36e-123 yrrS - - S - - - Protein of unknown function (DUF1510)
LNENKMEB_02567 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
LNENKMEB_02568 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LNENKMEB_02569 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LNENKMEB_02570 6.3e-311 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
LNENKMEB_02571 2.2e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
LNENKMEB_02572 2.22e-151 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
LNENKMEB_02573 8.08e-259 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LNENKMEB_02574 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
LNENKMEB_02575 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LNENKMEB_02576 1.29e-54 yrzL - - S - - - Belongs to the UPF0297 family
LNENKMEB_02577 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LNENKMEB_02578 3.29e-237 yrrI - - S - - - AI-2E family transporter
LNENKMEB_02579 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LNENKMEB_02580 4.27e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LNENKMEB_02581 1.13e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LNENKMEB_02582 1.87e-139 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LNENKMEB_02583 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
LNENKMEB_02584 8.4e-42 yrzR - - - - - - -
LNENKMEB_02585 1.76e-107 yrrD - - S - - - protein conserved in bacteria
LNENKMEB_02586 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LNENKMEB_02587 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
LNENKMEB_02588 3.55e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LNENKMEB_02589 4.24e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LNENKMEB_02590 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_02591 9.19e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LNENKMEB_02592 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LNENKMEB_02593 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LNENKMEB_02594 7.37e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LNENKMEB_02597 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
LNENKMEB_02598 2.86e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LNENKMEB_02599 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LNENKMEB_02600 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LNENKMEB_02601 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LNENKMEB_02602 2.14e-60 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
LNENKMEB_02603 2.18e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LNENKMEB_02604 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LNENKMEB_02605 1.65e-66 yrzD - - S - - - Post-transcriptional regulator
LNENKMEB_02606 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LNENKMEB_02607 2.03e-143 yrbG - - S - - - membrane
LNENKMEB_02608 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
LNENKMEB_02609 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
LNENKMEB_02610 2.01e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LNENKMEB_02611 5.79e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LNENKMEB_02612 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
LNENKMEB_02613 6.17e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LNENKMEB_02614 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LNENKMEB_02615 4.21e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
LNENKMEB_02617 8.92e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LNENKMEB_02618 8.47e-257 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
LNENKMEB_02619 1.04e-272 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LNENKMEB_02620 7.45e-196 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
LNENKMEB_02621 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
LNENKMEB_02622 5.48e-283 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LNENKMEB_02623 3.02e-124 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
LNENKMEB_02624 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
LNENKMEB_02625 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
LNENKMEB_02626 7.1e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LNENKMEB_02627 3.64e-140 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
LNENKMEB_02628 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LNENKMEB_02629 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
LNENKMEB_02630 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LNENKMEB_02631 3.59e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
LNENKMEB_02632 1.39e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LNENKMEB_02633 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
LNENKMEB_02634 6.85e-155 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LNENKMEB_02635 6.14e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
LNENKMEB_02636 1.77e-201 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LNENKMEB_02637 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
LNENKMEB_02638 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
LNENKMEB_02639 1e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
LNENKMEB_02640 1.54e-209 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
LNENKMEB_02641 1.81e-171 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LNENKMEB_02642 1.04e-304 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LNENKMEB_02643 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LNENKMEB_02644 1.53e-35 - - - - - - - -
LNENKMEB_02645 1.55e-250 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LNENKMEB_02646 4.99e-299 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
LNENKMEB_02647 1.62e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LNENKMEB_02648 6.92e-236 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
LNENKMEB_02649 1.62e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LNENKMEB_02650 5.19e-223 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LNENKMEB_02651 1.88e-186 hemX - - O ko:K02497 - ko00000 cytochrome C
LNENKMEB_02652 4.36e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LNENKMEB_02653 3.93e-114 ysxD - - - - - - -
LNENKMEB_02654 1.79e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LNENKMEB_02655 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LNENKMEB_02656 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
LNENKMEB_02657 3.28e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LNENKMEB_02658 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LNENKMEB_02659 3.19e-239 ysoA - - H - - - Tetratricopeptide repeat
LNENKMEB_02660 3.77e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LNENKMEB_02661 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LNENKMEB_02662 2.04e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LNENKMEB_02663 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LNENKMEB_02664 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LNENKMEB_02665 2.06e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LNENKMEB_02666 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LNENKMEB_02669 6.58e-162 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
LNENKMEB_02670 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
LNENKMEB_02671 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
LNENKMEB_02675 1.16e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
LNENKMEB_02676 3.2e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LNENKMEB_02677 1.44e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LNENKMEB_02678 4.47e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
LNENKMEB_02679 4.68e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LNENKMEB_02680 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
LNENKMEB_02681 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_02682 2.19e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
LNENKMEB_02683 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LNENKMEB_02684 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LNENKMEB_02685 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
LNENKMEB_02686 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
LNENKMEB_02687 8.64e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LNENKMEB_02688 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LNENKMEB_02689 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LNENKMEB_02690 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
LNENKMEB_02691 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
LNENKMEB_02692 1.74e-177 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
LNENKMEB_02693 2.48e-178 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
LNENKMEB_02694 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_02695 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LNENKMEB_02696 2.71e-160 ywbB - - S - - - Protein of unknown function (DUF2711)
LNENKMEB_02697 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
LNENKMEB_02698 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LNENKMEB_02699 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
LNENKMEB_02700 3.5e-108 yshB - - S - - - membrane protein, required for colicin V production
LNENKMEB_02701 3.48e-53 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LNENKMEB_02702 8.83e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LNENKMEB_02703 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LNENKMEB_02704 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LNENKMEB_02705 5.41e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LNENKMEB_02706 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
LNENKMEB_02707 1.52e-262 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
LNENKMEB_02708 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
LNENKMEB_02709 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
LNENKMEB_02710 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
LNENKMEB_02711 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
LNENKMEB_02712 2.79e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
LNENKMEB_02713 4.38e-215 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
LNENKMEB_02714 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
LNENKMEB_02715 1.65e-285 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LNENKMEB_02716 3.06e-181 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
LNENKMEB_02717 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LNENKMEB_02718 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
LNENKMEB_02719 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
LNENKMEB_02720 5.73e-240 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LNENKMEB_02721 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
LNENKMEB_02722 3.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
LNENKMEB_02723 5.25e-54 ysdA - - S - - - Membrane
LNENKMEB_02724 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LNENKMEB_02725 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LNENKMEB_02726 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LNENKMEB_02727 3.1e-147 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LNENKMEB_02728 1.12e-68 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
LNENKMEB_02729 3e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
LNENKMEB_02730 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_02731 7.21e-194 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
LNENKMEB_02732 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LNENKMEB_02733 1.63e-196 ytxC - - S - - - YtxC-like family
LNENKMEB_02734 1.81e-139 ytxB - - S - - - SNARE associated Golgi protein
LNENKMEB_02735 1.42e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LNENKMEB_02736 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
LNENKMEB_02737 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LNENKMEB_02738 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LNENKMEB_02739 2.19e-249 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LNENKMEB_02740 1.69e-89 ytcD - - K - - - Transcriptional regulator
LNENKMEB_02741 1.97e-259 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
LNENKMEB_02742 5.53e-206 ytbE - - S - - - reductase
LNENKMEB_02743 3.43e-127 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LNENKMEB_02744 2e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
LNENKMEB_02745 8.11e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LNENKMEB_02746 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LNENKMEB_02747 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
LNENKMEB_02748 1.38e-165 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LNENKMEB_02749 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
LNENKMEB_02750 1.32e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
LNENKMEB_02751 1.66e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LNENKMEB_02752 7.81e-83 yjdF3 - - S - - - Protein of unknown function (DUF2992)
LNENKMEB_02753 2.3e-95 ytwI - - S - - - membrane
LNENKMEB_02754 4.05e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
LNENKMEB_02755 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
LNENKMEB_02756 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LNENKMEB_02757 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LNENKMEB_02758 1.15e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LNENKMEB_02759 3.59e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LNENKMEB_02760 1.72e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LNENKMEB_02761 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LNENKMEB_02762 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
LNENKMEB_02763 2.64e-114 ytrI - - - - - - -
LNENKMEB_02764 1e-31 - - - - - - - -
LNENKMEB_02765 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
LNENKMEB_02766 3.05e-63 ytpI - - S - - - YtpI-like protein
LNENKMEB_02767 6.77e-305 ytoI - - K - - - transcriptional regulator containing CBS domains
LNENKMEB_02768 4.86e-165 ytkL - - S - - - Belongs to the UPF0173 family
LNENKMEB_02769 3.41e-183 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LNENKMEB_02771 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LNENKMEB_02772 5.02e-296 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LNENKMEB_02773 4.03e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
LNENKMEB_02774 2.33e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LNENKMEB_02775 3.18e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
LNENKMEB_02776 1.36e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LNENKMEB_02777 1.37e-99 ytfJ - - S - - - Sporulation protein YtfJ
LNENKMEB_02778 3.66e-156 ytfI - - S - - - Protein of unknown function (DUF2953)
LNENKMEB_02779 2.77e-114 yteJ - - S - - - RDD family
LNENKMEB_02780 6.39e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
LNENKMEB_02781 1.91e-195 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LNENKMEB_02782 0.0 ytcJ - - S - - - amidohydrolase
LNENKMEB_02783 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LNENKMEB_02784 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
LNENKMEB_02785 2.09e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LNENKMEB_02786 6.74e-267 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LNENKMEB_02787 1.96e-308 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LNENKMEB_02788 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LNENKMEB_02789 1.46e-196 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LNENKMEB_02790 2.41e-141 yttP - - K - - - Transcriptional regulator
LNENKMEB_02791 5.2e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LNENKMEB_02792 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
LNENKMEB_02793 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LNENKMEB_02794 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LNENKMEB_02795 1.81e-132 yokH - - G - - - SMI1 / KNR4 family
LNENKMEB_02796 4.14e-60 - - - D - - - nuclear chromosome segregation
LNENKMEB_02799 7.73e-61 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
LNENKMEB_02800 7.33e-24 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LNENKMEB_02801 5.58e-21 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LNENKMEB_02803 2.16e-282 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LNENKMEB_02805 9.55e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LNENKMEB_02807 2.49e-178 - - - E - - - GDSL-like Lipase/Acylhydrolase family
LNENKMEB_02808 4.99e-193 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LNENKMEB_02809 7.76e-191 - - - K - - - Transcriptional regulator
LNENKMEB_02810 5.77e-160 ygaZ - - E - - - AzlC protein
LNENKMEB_02811 2.07e-62 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
LNENKMEB_02812 3.46e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LNENKMEB_02813 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LNENKMEB_02814 4.72e-154 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LNENKMEB_02815 2.06e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
LNENKMEB_02816 1.42e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
LNENKMEB_02817 1.05e-155 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LNENKMEB_02818 5.2e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LNENKMEB_02819 5.91e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LNENKMEB_02820 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LNENKMEB_02821 8.39e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
LNENKMEB_02822 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
LNENKMEB_02823 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LNENKMEB_02824 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LNENKMEB_02825 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LNENKMEB_02826 2.43e-138 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LNENKMEB_02827 1.69e-190 ytpQ - - S - - - Belongs to the UPF0354 family
LNENKMEB_02828 5.47e-76 ytpP - - CO - - - Thioredoxin
LNENKMEB_02829 4.06e-102 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
LNENKMEB_02830 4.33e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
LNENKMEB_02831 9.96e-69 ytzB - - S - - - small secreted protein
LNENKMEB_02832 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LNENKMEB_02833 5.56e-211 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LNENKMEB_02834 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LNENKMEB_02835 3.88e-60 ytzH - - S - - - YtzH-like protein
LNENKMEB_02836 2.93e-199 ytmP - - M - - - Phosphotransferase
LNENKMEB_02837 8.33e-227 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LNENKMEB_02838 2.85e-214 ytlQ - - - - - - -
LNENKMEB_02839 2.21e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LNENKMEB_02840 2.38e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LNENKMEB_02841 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
LNENKMEB_02842 2.99e-290 pbuO - - S ko:K06901 - ko00000,ko02000 permease
LNENKMEB_02843 2.6e-278 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
LNENKMEB_02844 6.35e-164 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LNENKMEB_02845 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
LNENKMEB_02846 8.68e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LNENKMEB_02847 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LNENKMEB_02848 3.73e-299 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
LNENKMEB_02849 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
LNENKMEB_02850 2.14e-36 yteV - - S - - - Sporulation protein Cse60
LNENKMEB_02851 3.87e-239 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_02852 6.55e-310 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LNENKMEB_02853 2.54e-214 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LNENKMEB_02854 1.17e-183 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LNENKMEB_02855 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
LNENKMEB_02856 1.69e-111 - - - M - - - Acetyltransferase (GNAT) domain
LNENKMEB_02857 6.05e-69 ytwF - - P - - - Sulfurtransferase
LNENKMEB_02858 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LNENKMEB_02859 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
LNENKMEB_02860 6.17e-177 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LNENKMEB_02861 2.46e-271 yttB - - EGP - - - Major facilitator superfamily
LNENKMEB_02862 1.08e-159 ywaF - - S - - - Integral membrane protein
LNENKMEB_02863 7.27e-252 - - - L - - - COG3666 Transposase and inactivated derivatives
LNENKMEB_02864 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
LNENKMEB_02865 2.68e-173 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_02866 5.86e-220 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
LNENKMEB_02867 2.6e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LNENKMEB_02868 1.93e-287 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LNENKMEB_02869 2.12e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_02870 5.2e-209 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
LNENKMEB_02871 2.8e-230 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LNENKMEB_02872 6.76e-222 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LNENKMEB_02873 2.08e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_02874 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
LNENKMEB_02875 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
LNENKMEB_02876 1.13e-249 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LNENKMEB_02877 0.0 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LNENKMEB_02878 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
LNENKMEB_02879 3.1e-137 ytqB - - J - - - Putative rRNA methylase
LNENKMEB_02881 6.33e-186 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
LNENKMEB_02882 1.86e-269 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
LNENKMEB_02883 5.71e-193 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
LNENKMEB_02884 4.06e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNENKMEB_02885 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LNENKMEB_02886 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LNENKMEB_02887 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LNENKMEB_02888 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LNENKMEB_02889 1.23e-151 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
LNENKMEB_02890 8.3e-66 - - - L - - - transposase activity
LNENKMEB_02891 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
LNENKMEB_02892 1.29e-188 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LNENKMEB_02893 3.72e-238 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LNENKMEB_02894 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LNENKMEB_02895 2.19e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LNENKMEB_02896 4.13e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LNENKMEB_02897 1.23e-79 ytkC - - S - - - Bacteriophage holin family
LNENKMEB_02898 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LNENKMEB_02900 5.15e-100 ytkA - - S - - - YtkA-like
LNENKMEB_02901 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LNENKMEB_02902 6.93e-53 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
LNENKMEB_02903 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LNENKMEB_02904 8.35e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LNENKMEB_02905 6.36e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LNENKMEB_02906 1.75e-233 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LNENKMEB_02907 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
LNENKMEB_02908 1.43e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LNENKMEB_02909 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LNENKMEB_02910 7.52e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LNENKMEB_02911 7.22e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LNENKMEB_02912 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LNENKMEB_02913 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LNENKMEB_02914 6.11e-169 yteA - - T - - - COG1734 DnaK suppressor protein
LNENKMEB_02915 9.03e-103 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
LNENKMEB_02937 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LNENKMEB_02939 1.46e-126 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
LNENKMEB_02940 1.02e-275 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
LNENKMEB_02941 1.96e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
LNENKMEB_02942 8.91e-106 yuaE - - S - - - DinB superfamily
LNENKMEB_02943 6.79e-141 - - - S - - - MOSC domain
LNENKMEB_02944 1.43e-289 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
LNENKMEB_02945 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LNENKMEB_02946 1.18e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
LNENKMEB_02947 2.03e-122 yuaB - - - - - - -
LNENKMEB_02948 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LNENKMEB_02949 2.58e-191 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LNENKMEB_02950 1.9e-278 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LNENKMEB_02951 3.19e-158 - - - G - - - Cupin
LNENKMEB_02952 1.11e-70 yjcN - - - - - - -
LNENKMEB_02954 3.79e-186 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LNENKMEB_02955 9.96e-251 yubA - - S - - - transporter activity
LNENKMEB_02956 7.8e-237 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LNENKMEB_02957 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
LNENKMEB_02958 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LNENKMEB_02959 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LNENKMEB_02960 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LNENKMEB_02961 1.89e-315 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LNENKMEB_02962 9.03e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
LNENKMEB_02963 2.46e-48 - - - - - - - -
LNENKMEB_02964 8.52e-244 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LNENKMEB_02965 2.69e-98 yugU - - S - - - Uncharacterised protein family UPF0047
LNENKMEB_02966 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LNENKMEB_02967 1.63e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LNENKMEB_02968 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
LNENKMEB_02969 1.24e-22 - - - - - - - -
LNENKMEB_02970 2.44e-35 mstX - - S - - - Membrane-integrating protein Mistic
LNENKMEB_02971 9.77e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
LNENKMEB_02972 3.48e-94 yugN - - S - - - YugN-like family
LNENKMEB_02974 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LNENKMEB_02975 1.95e-133 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
LNENKMEB_02976 4.34e-152 ycaC - - Q - - - Isochorismatase family
LNENKMEB_02977 3.92e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
LNENKMEB_02978 6.7e-286 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
LNENKMEB_02979 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
LNENKMEB_02980 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LNENKMEB_02981 3.94e-265 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
LNENKMEB_02982 3.75e-109 alaR - - K - - - Transcriptional regulator
LNENKMEB_02983 4.03e-200 yugF - - I - - - Hydrolase
LNENKMEB_02984 3.5e-54 yugE - - S - - - Domain of unknown function (DUF1871)
LNENKMEB_02985 4.53e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LNENKMEB_02986 1.81e-292 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_02987 6.88e-89 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
LNENKMEB_02988 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
LNENKMEB_02989 1.3e-263 yuxJ - - EGP - - - Major facilitator superfamily
LNENKMEB_02990 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
LNENKMEB_02991 5.29e-95 yuxK - - S - - - protein conserved in bacteria
LNENKMEB_02992 1.6e-101 yufK - - S - - - Family of unknown function (DUF5366)
LNENKMEB_02993 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LNENKMEB_02994 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LNENKMEB_02995 4.98e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
LNENKMEB_02996 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_02997 2.72e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LNENKMEB_02998 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LNENKMEB_03000 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LNENKMEB_03001 5.39e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LNENKMEB_03002 6.01e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LNENKMEB_03003 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LNENKMEB_03004 1.23e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LNENKMEB_03005 1.91e-52 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LNENKMEB_03006 4.2e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
LNENKMEB_03007 4e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
LNENKMEB_03008 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LNENKMEB_03009 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_03011 1.7e-111 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
LNENKMEB_03012 2.66e-11 - - - S - - - DegQ (SacQ) family
LNENKMEB_03013 1.04e-67 yuzC - - - - - - -
LNENKMEB_03014 6.86e-296 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
LNENKMEB_03015 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LNENKMEB_03016 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
LNENKMEB_03017 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
LNENKMEB_03018 5.46e-51 yueH - - S - - - YueH-like protein
LNENKMEB_03019 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
LNENKMEB_03020 1.88e-238 yueF - - S - - - transporter activity
LNENKMEB_03021 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
LNENKMEB_03022 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
LNENKMEB_03023 2.29e-166 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LNENKMEB_03024 8.01e-102 yueC - - S - - - Family of unknown function (DUF5383)
LNENKMEB_03025 0.0 yueB - - S - - - type VII secretion protein EsaA
LNENKMEB_03026 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LNENKMEB_03027 7.95e-276 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
LNENKMEB_03028 5.28e-53 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
LNENKMEB_03029 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
LNENKMEB_03030 5.19e-292 yukF - - QT - - - Transcriptional regulator
LNENKMEB_03031 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
LNENKMEB_03032 3.58e-170 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
LNENKMEB_03033 1.91e-46 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
LNENKMEB_03034 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LNENKMEB_03035 4.79e-221 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
LNENKMEB_03036 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
LNENKMEB_03037 1.36e-286 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LNENKMEB_03038 1.22e-171 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LNENKMEB_03039 1.47e-210 eSD - - S ko:K07017 - ko00000 Putative esterase
LNENKMEB_03040 1.13e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
LNENKMEB_03041 3.73e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
LNENKMEB_03042 2.86e-276 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
LNENKMEB_03043 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LNENKMEB_03044 4.99e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
LNENKMEB_03045 7.98e-150 yuiC - - S - - - protein conserved in bacteria
LNENKMEB_03046 8.54e-46 yuiB - - S - - - Putative membrane protein
LNENKMEB_03047 1.39e-299 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LNENKMEB_03048 1.03e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
LNENKMEB_03050 4.7e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LNENKMEB_03051 5.68e-40 - - - - - - - -
LNENKMEB_03052 5.92e-93 - - - CP - - - Membrane
LNENKMEB_03053 1.18e-159 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LNENKMEB_03055 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
LNENKMEB_03057 7.08e-123 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
LNENKMEB_03058 9.01e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LNENKMEB_03059 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
LNENKMEB_03060 5.54e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LNENKMEB_03061 1.49e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LNENKMEB_03062 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
LNENKMEB_03063 8.47e-266 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LNENKMEB_03064 3.29e-73 yuzD - - S - - - protein conserved in bacteria
LNENKMEB_03065 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
LNENKMEB_03066 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
LNENKMEB_03067 2.26e-215 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LNENKMEB_03068 2.8e-252 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LNENKMEB_03069 1.43e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LNENKMEB_03070 1.55e-250 yutH - - S - - - Spore coat protein
LNENKMEB_03071 1.5e-109 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
LNENKMEB_03072 4.31e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LNENKMEB_03073 1.55e-95 yutE - - S - - - Protein of unknown function DUF86
LNENKMEB_03074 3.71e-62 yutD - - S - - - protein conserved in bacteria
LNENKMEB_03075 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LNENKMEB_03076 1.66e-250 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
LNENKMEB_03077 3.21e-166 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
LNENKMEB_03078 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LNENKMEB_03079 3.01e-186 yunE - - S ko:K07090 - ko00000 membrane transporter protein
LNENKMEB_03080 2.02e-214 yunF - - S - - - Protein of unknown function DUF72
LNENKMEB_03081 6.14e-80 - - - S - - - phosphoglycolate phosphatase activity
LNENKMEB_03082 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LNENKMEB_03083 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
LNENKMEB_03085 1.17e-174 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
LNENKMEB_03087 5.84e-83 - - - - - - - -
LNENKMEB_03088 5.21e-275 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LNENKMEB_03089 5.95e-302 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LNENKMEB_03090 1.2e-299 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LNENKMEB_03091 7.06e-218 bsn - - L - - - Ribonuclease
LNENKMEB_03092 1.58e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LNENKMEB_03093 5.89e-173 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
LNENKMEB_03094 4.37e-205 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
LNENKMEB_03095 3.6e-209 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
LNENKMEB_03096 5.26e-203 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LNENKMEB_03097 2.12e-312 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
LNENKMEB_03098 3.87e-237 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LNENKMEB_03099 1.11e-210 - - - K - - - helix_turn_helix, mercury resistance
LNENKMEB_03102 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
LNENKMEB_03103 1.83e-259 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
LNENKMEB_03104 1.79e-164 - - - Q - - - ubiE/COQ5 methyltransferase family
LNENKMEB_03105 2.82e-100 yncE - - S - - - Protein of unknown function (DUF2691)
LNENKMEB_03106 3.07e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LNENKMEB_03107 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
LNENKMEB_03108 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
LNENKMEB_03109 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LNENKMEB_03110 8.67e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
LNENKMEB_03111 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LNENKMEB_03112 2.54e-84 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LNENKMEB_03113 4.46e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
LNENKMEB_03114 1.46e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
LNENKMEB_03115 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LNENKMEB_03116 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
LNENKMEB_03117 1.64e-72 yusE - - CO - - - Thioredoxin
LNENKMEB_03118 1.08e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
LNENKMEB_03119 5.16e-54 yusG - - S - - - Protein of unknown function (DUF2553)
LNENKMEB_03120 2.41e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LNENKMEB_03121 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
LNENKMEB_03122 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LNENKMEB_03123 9.03e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
LNENKMEB_03124 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
LNENKMEB_03125 1.31e-215 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LNENKMEB_03126 7.8e-264 yusP - - P - - - Major facilitator superfamily
LNENKMEB_03127 3.2e-58 - - - - - - - -
LNENKMEB_03128 4.46e-72 yusN - - M - - - Coat F domain
LNENKMEB_03129 9.65e-92 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
LNENKMEB_03130 0.0 yusP - - P - - - Major facilitator superfamily
LNENKMEB_03131 1.69e-86 yusQ - - S - - - Tautomerase enzyme
LNENKMEB_03132 2.11e-168 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LNENKMEB_03133 2.44e-206 yusT - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
LNENKMEB_03134 1.52e-206 - - - K - - - Transcriptional regulator
LNENKMEB_03135 3.69e-179 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
LNENKMEB_03136 4.9e-240 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LNENKMEB_03137 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
LNENKMEB_03138 1.29e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LNENKMEB_03139 2.66e-60 - - - S - - - YusW-like protein
LNENKMEB_03140 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
LNENKMEB_03141 4.68e-198 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LNENKMEB_03142 4.12e-103 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LNENKMEB_03143 6.82e-308 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LNENKMEB_03144 3.17e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LNENKMEB_03145 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_03146 4.63e-33 - - - - - - - -
LNENKMEB_03147 3.11e-201 yuxN - - K - - - Transcriptional regulator
LNENKMEB_03148 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LNENKMEB_03149 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
LNENKMEB_03150 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LNENKMEB_03151 1.03e-242 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LNENKMEB_03152 7.85e-265 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
LNENKMEB_03153 2.91e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LNENKMEB_03154 9.98e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_03155 8.92e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
LNENKMEB_03156 2.03e-192 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
LNENKMEB_03157 3.96e-133 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LNENKMEB_03158 1.62e-68 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
LNENKMEB_03159 1.43e-291 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LNENKMEB_03160 3.1e-131 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
LNENKMEB_03161 1.79e-287 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LNENKMEB_03162 7.97e-231 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LNENKMEB_03163 1.36e-214 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LNENKMEB_03164 1.23e-180 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LNENKMEB_03165 1.09e-218 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
LNENKMEB_03166 0.0 yvrG - - T - - - Histidine kinase
LNENKMEB_03167 7.74e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LNENKMEB_03168 3.96e-49 - - - - - - - -
LNENKMEB_03169 3.23e-134 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
LNENKMEB_03170 3.78e-21 - - - S - - - YvrJ protein family
LNENKMEB_03171 3.11e-295 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LNENKMEB_03172 3.41e-88 yvrL - - S - - - Regulatory protein YrvL
LNENKMEB_03173 1.97e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LNENKMEB_03174 1.37e-225 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LNENKMEB_03175 1.56e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LNENKMEB_03176 2.21e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LNENKMEB_03177 3.57e-159 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LNENKMEB_03178 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
LNENKMEB_03179 1.29e-20 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
LNENKMEB_03180 3.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
LNENKMEB_03181 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
LNENKMEB_03182 1.65e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
LNENKMEB_03183 1.95e-178 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
LNENKMEB_03184 1.57e-122 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
LNENKMEB_03185 2.05e-146 yfiK - - K - - - Regulator
LNENKMEB_03186 8.62e-253 - - - T - - - Histidine kinase
LNENKMEB_03187 1.42e-219 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
LNENKMEB_03188 1.12e-244 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LNENKMEB_03189 4.86e-260 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LNENKMEB_03190 7.23e-200 yvgN - - S - - - reductase
LNENKMEB_03191 1.38e-113 yvgO - - - - - - -
LNENKMEB_03192 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
LNENKMEB_03193 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LNENKMEB_03194 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LNENKMEB_03195 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LNENKMEB_03196 3.02e-76 yvgT - - S - - - membrane
LNENKMEB_03197 4.49e-189 - - - S - - - Metallo-peptidase family M12
LNENKMEB_03198 3.56e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
LNENKMEB_03199 3.33e-140 bdbD - - O - - - Thioredoxin
LNENKMEB_03200 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LNENKMEB_03201 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LNENKMEB_03202 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
LNENKMEB_03203 8.06e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
LNENKMEB_03204 4.77e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LNENKMEB_03205 5.95e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LNENKMEB_03206 4.39e-209 - - - K - - - Helix-turn-helix XRE-family like proteins
LNENKMEB_03207 6.18e-282 - - - EGP - - - Major Facilitator Superfamily
LNENKMEB_03208 9.11e-92 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
LNENKMEB_03209 1.19e-186 - - - S ko:K07045 - ko00000 Amidohydrolase
LNENKMEB_03210 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LNENKMEB_03211 1.01e-61 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
LNENKMEB_03212 2.05e-231 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LNENKMEB_03213 9e-181 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LNENKMEB_03214 5.8e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LNENKMEB_03215 1.79e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LNENKMEB_03216 1.5e-189 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
LNENKMEB_03217 7.18e-169 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
LNENKMEB_03218 6.38e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LNENKMEB_03219 1.14e-205 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
LNENKMEB_03220 1.13e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LNENKMEB_03221 1.19e-65 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
LNENKMEB_03222 3.13e-51 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
LNENKMEB_03224 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LNENKMEB_03225 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LNENKMEB_03226 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
LNENKMEB_03227 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
LNENKMEB_03228 1.64e-47 yvzC - - K - - - transcriptional
LNENKMEB_03229 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
LNENKMEB_03230 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
LNENKMEB_03231 2.97e-70 yvaP - - K - - - transcriptional
LNENKMEB_03232 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
LNENKMEB_03233 1.29e-156 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
LNENKMEB_03234 4.95e-170 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LNENKMEB_03235 8.13e-156 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LNENKMEB_03236 1.27e-160 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_03237 2.09e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LNENKMEB_03238 5.39e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LNENKMEB_03239 3.4e-146 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LNENKMEB_03240 1.17e-267 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LNENKMEB_03241 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LNENKMEB_03242 6.21e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LNENKMEB_03243 5.39e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LNENKMEB_03244 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LNENKMEB_03245 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LNENKMEB_03246 4.11e-129 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LNENKMEB_03247 1.88e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
LNENKMEB_03248 2.66e-157 yvbI - - M - - - Membrane
LNENKMEB_03249 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LNENKMEB_03250 1.11e-106 yvbK - - K - - - acetyltransferase
LNENKMEB_03251 7.68e-270 - - - EGP - - - Major facilitator Superfamily
LNENKMEB_03252 4.84e-229 - - - - - - - -
LNENKMEB_03253 7.75e-163 - - - S - - - GlcNAc-PI de-N-acetylase
LNENKMEB_03254 1.37e-183 - - - C - - - WbqC-like protein family
LNENKMEB_03255 1.59e-191 - - - M - - - Protein involved in cellulose biosynthesis
LNENKMEB_03256 5.32e-285 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LNENKMEB_03257 4.08e-218 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
LNENKMEB_03258 1.89e-275 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
LNENKMEB_03259 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LNENKMEB_03260 1.78e-305 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
LNENKMEB_03261 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LNENKMEB_03262 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
LNENKMEB_03263 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LNENKMEB_03264 3.98e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LNENKMEB_03265 4.7e-237 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LNENKMEB_03266 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LNENKMEB_03268 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LNENKMEB_03269 3.31e-262 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
LNENKMEB_03271 1.41e-240 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LNENKMEB_03273 1.06e-200 yvbU - - K - - - Transcriptional regulator
LNENKMEB_03274 5.22e-203 yvbV - - EG - - - EamA-like transporter family
LNENKMEB_03275 4.71e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LNENKMEB_03276 0.0 - - - - - - - -
LNENKMEB_03277 3.55e-231 yhjM - - K - - - Transcriptional regulator
LNENKMEB_03278 5.19e-148 - - - S ko:K07149 - ko00000 Membrane
LNENKMEB_03279 8.53e-213 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LNENKMEB_03280 1.56e-194 gntR - - K - - - RpiR family transcriptional regulator
LNENKMEB_03281 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LNENKMEB_03282 1.37e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
LNENKMEB_03283 1.44e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LNENKMEB_03284 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LNENKMEB_03285 6.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LNENKMEB_03286 2.21e-275 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LNENKMEB_03287 1.26e-155 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
LNENKMEB_03288 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LNENKMEB_03289 4.23e-305 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LNENKMEB_03290 4.01e-44 yvfG - - S - - - YvfG protein
LNENKMEB_03291 8.14e-240 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
LNENKMEB_03292 3.31e-283 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
LNENKMEB_03293 5.73e-79 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LNENKMEB_03294 1.92e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LNENKMEB_03295 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LNENKMEB_03296 6.3e-251 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LNENKMEB_03297 2.23e-258 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
LNENKMEB_03298 1.61e-249 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LNENKMEB_03299 1.64e-260 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
LNENKMEB_03300 9.63e-270 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LNENKMEB_03301 3.2e-205 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
LNENKMEB_03302 3.53e-277 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
LNENKMEB_03303 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LNENKMEB_03304 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LNENKMEB_03305 1.17e-155 epsA - - M ko:K19420 - ko00000 biosynthesis protein
LNENKMEB_03306 3.45e-100 - - - K ko:K19417 - ko00000,ko03000 transcriptional
LNENKMEB_03307 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
LNENKMEB_03308 3.85e-125 ywjB - - H - - - RibD C-terminal domain
LNENKMEB_03309 2.51e-144 yyaS - - S ko:K07149 - ko00000 Membrane
LNENKMEB_03310 5.46e-119 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LNENKMEB_03311 2.47e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
LNENKMEB_03312 3.82e-16 - - - S - - - Protein of unknown function (DUF1433)
LNENKMEB_03313 3.36e-62 - - - S - - - Protein of unknown function (DUF1433)
LNENKMEB_03314 1.54e-50 - - - IU - - - Lipase (class 3)
LNENKMEB_03315 1.43e-33 - - - S - - - Protein of unknown function (DUF1433)
LNENKMEB_03316 3.67e-34 - - - S - - - Protein of unknown function (DUF1433)
LNENKMEB_03317 3.97e-16 - - - S - - - Protein of unknown function (DUF1433)
LNENKMEB_03318 0.0 - - - I - - - Pfam Lipase (class 3)
LNENKMEB_03319 1.94e-47 - - - - - - - -
LNENKMEB_03321 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LNENKMEB_03322 2.01e-285 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
LNENKMEB_03323 1.57e-234 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
LNENKMEB_03324 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LNENKMEB_03325 3.9e-209 yraN - - K - - - Transcriptional regulator
LNENKMEB_03326 1.22e-271 yraM - - S - - - PrpF protein
LNENKMEB_03327 0.0 - - - EGP - - - Sugar (and other) transporter
LNENKMEB_03329 3.78e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
LNENKMEB_03330 1.3e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
LNENKMEB_03331 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LNENKMEB_03332 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LNENKMEB_03333 1.02e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LNENKMEB_03334 9.2e-104 - - - M - - - Ribonuclease
LNENKMEB_03335 6.92e-184 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
LNENKMEB_03336 2.76e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
LNENKMEB_03337 1.48e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LNENKMEB_03338 8.99e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LNENKMEB_03339 4.93e-212 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LNENKMEB_03340 5.15e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LNENKMEB_03341 8.99e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LNENKMEB_03342 7.1e-202 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
LNENKMEB_03343 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
LNENKMEB_03344 5.55e-245 sasA - - T - - - Histidine kinase
LNENKMEB_03345 3.99e-158 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LNENKMEB_03346 5.51e-73 - - - - - - - -
LNENKMEB_03347 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LNENKMEB_03348 8.12e-144 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
LNENKMEB_03349 3.4e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LNENKMEB_03350 3.95e-168 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LNENKMEB_03351 1.63e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LNENKMEB_03352 6.76e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
LNENKMEB_03353 4.31e-296 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LNENKMEB_03354 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LNENKMEB_03355 6.03e-270 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LNENKMEB_03356 4.16e-177 yvpB - - NU - - - protein conserved in bacteria
LNENKMEB_03357 4.65e-95 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LNENKMEB_03358 8.12e-158 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LNENKMEB_03359 1.39e-190 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LNENKMEB_03360 6e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LNENKMEB_03361 2.74e-285 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LNENKMEB_03362 9.04e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LNENKMEB_03363 1.75e-170 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
LNENKMEB_03364 1.27e-135 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LNENKMEB_03365 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
LNENKMEB_03366 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
LNENKMEB_03367 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LNENKMEB_03368 3.2e-218 yvlB - - S - - - Putative adhesin
LNENKMEB_03369 4.87e-66 yvlA - - - - - - -
LNENKMEB_03370 1.78e-51 yvkN - - - - - - -
LNENKMEB_03371 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LNENKMEB_03372 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LNENKMEB_03373 2.59e-45 csbA - - S - - - protein conserved in bacteria
LNENKMEB_03374 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
LNENKMEB_03375 2.32e-144 yvkB - - K - - - Transcriptional regulator
LNENKMEB_03376 5.92e-298 yvkA - - P - - - -transporter
LNENKMEB_03377 3.53e-34 - - - Q - - - Thioesterase domain
LNENKMEB_03379 6.39e-233 - - - S - - - Psort location CytoplasmicMembrane, score
LNENKMEB_03380 1.23e-58 - - - E - - - Saccharopine dehydrogenase
LNENKMEB_03381 1.47e-116 - - - V - - - ABC transporter transmembrane region
LNENKMEB_03382 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
LNENKMEB_03383 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
LNENKMEB_03385 6.18e-282 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LNENKMEB_03386 2.47e-73 swrA - - S - - - Swarming motility protein
LNENKMEB_03387 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LNENKMEB_03388 1.5e-298 ywoF - - P - - - Right handed beta helix region
LNENKMEB_03389 7.34e-197 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LNENKMEB_03390 8.68e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
LNENKMEB_03391 5.11e-59 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LNENKMEB_03392 4.82e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LNENKMEB_03393 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LNENKMEB_03394 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LNENKMEB_03395 3.94e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LNENKMEB_03396 1.35e-89 - - - - - - - -
LNENKMEB_03397 5.61e-10 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
LNENKMEB_03398 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
LNENKMEB_03399 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LNENKMEB_03400 1.97e-139 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LNENKMEB_03401 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LNENKMEB_03402 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LNENKMEB_03403 2.8e-108 yviE - - - - - - -
LNENKMEB_03404 1.4e-207 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
LNENKMEB_03405 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
LNENKMEB_03406 2.2e-105 yvyG - - NOU - - - FlgN protein
LNENKMEB_03407 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
LNENKMEB_03408 1.1e-97 yvyF - - S - - - flagellar protein
LNENKMEB_03409 2e-85 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
LNENKMEB_03410 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
LNENKMEB_03411 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LNENKMEB_03412 8.45e-202 degV - - S - - - protein conserved in bacteria
LNENKMEB_03413 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LNENKMEB_03414 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LNENKMEB_03415 1.2e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
LNENKMEB_03416 3.83e-230 yvhJ - - K - - - Transcriptional regulator
LNENKMEB_03417 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LNENKMEB_03418 7.13e-298 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
LNENKMEB_03419 2.82e-185 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LNENKMEB_03420 1.22e-148 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
LNENKMEB_03421 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
LNENKMEB_03422 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LNENKMEB_03423 1.36e-286 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
LNENKMEB_03424 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LNENKMEB_03425 4.22e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LNENKMEB_03426 1.99e-264 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LNENKMEB_03427 0.0 lytB - - D - - - Stage II sporulation protein
LNENKMEB_03428 3.45e-40 - - - - - - - -
LNENKMEB_03429 2.33e-179 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LNENKMEB_03430 1.2e-234 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LNENKMEB_03431 3.04e-200 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LNENKMEB_03432 9.74e-238 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LNENKMEB_03433 5.47e-174 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
LNENKMEB_03434 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LNENKMEB_03435 7.22e-305 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
LNENKMEB_03436 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
LNENKMEB_03437 6.38e-184 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LNENKMEB_03438 1.21e-266 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LNENKMEB_03439 9.86e-169 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LNENKMEB_03440 4.04e-242 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LNENKMEB_03441 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LNENKMEB_03442 4.46e-254 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LNENKMEB_03443 1.73e-271 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
LNENKMEB_03444 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
LNENKMEB_03445 6.9e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LNENKMEB_03446 2.3e-229 ywtF_2 - - K - - - Transcriptional regulator
LNENKMEB_03447 1.3e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LNENKMEB_03448 1.82e-76 yttA - - S - - - Pfam Transposase IS66
LNENKMEB_03449 6.71e-305 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LNENKMEB_03450 4.04e-29 ywtC - - - - - - -
LNENKMEB_03451 1.39e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LNENKMEB_03452 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
LNENKMEB_03453 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
LNENKMEB_03454 2.54e-241 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
LNENKMEB_03455 4.4e-247 - - - E - - - Spore germination protein
LNENKMEB_03456 2.62e-262 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
LNENKMEB_03457 4.28e-228 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
LNENKMEB_03458 6.91e-202 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LNENKMEB_03459 5.6e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LNENKMEB_03460 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LNENKMEB_03461 1.87e-205 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LNENKMEB_03462 6.93e-208 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
LNENKMEB_03463 3.54e-117 batE - - T - - - Sh3 type 3 domain protein
LNENKMEB_03464 5.02e-123 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
LNENKMEB_03465 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
LNENKMEB_03466 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LNENKMEB_03467 3.09e-214 alsR - - K - - - LysR substrate binding domain
LNENKMEB_03468 1.04e-306 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LNENKMEB_03469 3.43e-163 ywrJ - - - - - - -
LNENKMEB_03470 1.29e-185 cotB - - - ko:K06325 - ko00000 -
LNENKMEB_03471 2.76e-271 cotH - - M ko:K06330 - ko00000 Spore Coat
LNENKMEB_03472 9.51e-25 - - - - - - - -
LNENKMEB_03473 1.99e-144 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LNENKMEB_03474 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LNENKMEB_03475 1.01e-109 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LNENKMEB_03476 2.96e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
LNENKMEB_03477 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
LNENKMEB_03478 8.72e-173 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LNENKMEB_03479 7.91e-120 - - - - - - - -
LNENKMEB_03480 6.52e-98 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
LNENKMEB_03481 8.47e-84 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
LNENKMEB_03482 1.39e-298 ywqJ - - S - - - Pre-toxin TG
LNENKMEB_03483 2.09e-50 ywqI - - S - - - Family of unknown function (DUF5344)
LNENKMEB_03486 3.43e-191 ywqG - - S - - - Domain of unknown function (DUF1963)
LNENKMEB_03487 3.55e-313 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LNENKMEB_03488 2.13e-181 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
LNENKMEB_03489 6.33e-157 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LNENKMEB_03490 1.01e-151 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
LNENKMEB_03491 1.74e-21 - - - - - - - -
LNENKMEB_03492 0.0 ywqB - - S - - - SWIM zinc finger
LNENKMEB_03493 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LNENKMEB_03494 7.5e-202 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LNENKMEB_03495 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LNENKMEB_03496 5.13e-77 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
LNENKMEB_03497 4.49e-82 ywpG - - - - - - -
LNENKMEB_03498 9.16e-91 ywpF - - S - - - YwpF-like protein
LNENKMEB_03499 7.6e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LNENKMEB_03500 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LNENKMEB_03501 9.03e-256 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
LNENKMEB_03502 1.55e-186 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LNENKMEB_03503 1.03e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LNENKMEB_03504 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
LNENKMEB_03505 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
LNENKMEB_03506 3.58e-93 ywoH - - K - - - transcriptional
LNENKMEB_03507 2.89e-272 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LNENKMEB_03508 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
LNENKMEB_03509 2.69e-310 ywoD - - EGP - - - Major facilitator superfamily
LNENKMEB_03510 1.37e-133 yjgF - - Q - - - Isochorismatase family
LNENKMEB_03511 2.67e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
LNENKMEB_03512 1.07e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
LNENKMEB_03513 4.22e-267 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LNENKMEB_03514 5.79e-132 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
LNENKMEB_03515 6.63e-95 ywnJ - - S - - - VanZ like family
LNENKMEB_03516 1.31e-188 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LNENKMEB_03517 1.6e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
LNENKMEB_03519 2.55e-90 ywnF - - S - - - Family of unknown function (DUF5392)
LNENKMEB_03520 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LNENKMEB_03521 1.97e-79 ywnC - - S - - - Family of unknown function (DUF5362)
LNENKMEB_03522 5.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
LNENKMEB_03523 3.09e-88 ywnA - - K - - - Transcriptional regulator
LNENKMEB_03524 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LNENKMEB_03525 1.85e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
LNENKMEB_03526 2.86e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
LNENKMEB_03527 2.94e-17 csbD - - K - - - CsbD-like
LNENKMEB_03528 1.01e-105 ywmF - - S - - - Peptidase M50
LNENKMEB_03529 8.9e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LNENKMEB_03530 1.31e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LNENKMEB_03531 6.12e-185 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LNENKMEB_03533 2.13e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LNENKMEB_03534 1.42e-148 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LNENKMEB_03535 3.47e-243 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
LNENKMEB_03536 2.87e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LNENKMEB_03537 6.86e-174 ywmB - - S - - - TATA-box binding
LNENKMEB_03538 2.25e-45 ywzB - - S - - - membrane
LNENKMEB_03539 7.17e-118 ywmA - - - - - - -
LNENKMEB_03540 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LNENKMEB_03541 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LNENKMEB_03542 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LNENKMEB_03543 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LNENKMEB_03544 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LNENKMEB_03545 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LNENKMEB_03546 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LNENKMEB_03547 1.05e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LNENKMEB_03548 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
LNENKMEB_03549 3.18e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LNENKMEB_03550 1.7e-300 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LNENKMEB_03551 3.68e-125 ywlG - - S - - - Belongs to the UPF0340 family
LNENKMEB_03552 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
LNENKMEB_03553 2.08e-101 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LNENKMEB_03554 4.76e-119 mntP - - P - - - Probably functions as a manganese efflux pump
LNENKMEB_03555 1.53e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LNENKMEB_03556 2.45e-98 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
LNENKMEB_03557 1e-147 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
LNENKMEB_03558 2.08e-79 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LNENKMEB_03560 6.95e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LNENKMEB_03561 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LNENKMEB_03562 3.7e-88 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LNENKMEB_03563 1.21e-122 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LNENKMEB_03564 2.02e-202 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
LNENKMEB_03565 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LNENKMEB_03566 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LNENKMEB_03567 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
LNENKMEB_03568 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LNENKMEB_03569 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
LNENKMEB_03570 5.55e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LNENKMEB_03571 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LNENKMEB_03572 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
LNENKMEB_03573 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
LNENKMEB_03574 8.11e-121 ywjG - - S - - - Domain of unknown function (DUF2529)
LNENKMEB_03575 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LNENKMEB_03576 3.41e-75 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LNENKMEB_03577 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
LNENKMEB_03578 9.92e-285 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LNENKMEB_03579 3.3e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LNENKMEB_03580 6.53e-58 ywjC - - - - - - -
LNENKMEB_03581 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
LNENKMEB_03582 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LNENKMEB_03583 5.01e-135 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LNENKMEB_03584 2.41e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
LNENKMEB_03585 8.93e-124 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
LNENKMEB_03586 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
LNENKMEB_03587 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LNENKMEB_03588 2.91e-109 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
LNENKMEB_03589 4.34e-178 ywiC - - S - - - YwiC-like protein
LNENKMEB_03590 1.33e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
LNENKMEB_03591 1.05e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LNENKMEB_03592 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LNENKMEB_03593 1.09e-94 ywiB - - S - - - protein conserved in bacteria
LNENKMEB_03595 2.12e-309 ywhL - - CO - - - amine dehydrogenase activity
LNENKMEB_03596 1.27e-279 ywhK - - CO - - - amine dehydrogenase activity
LNENKMEB_03597 2.32e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LNENKMEB_03599 9.15e-41 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
LNENKMEB_03600 2.41e-45 - - - - - - - -
LNENKMEB_03601 1.18e-38 - - - S - - - Domain of unknown function (DUF4177)
LNENKMEB_03603 8.45e-101 - - - CP - - - Membrane
LNENKMEB_03606 1.22e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LNENKMEB_03607 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LNENKMEB_03608 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LNENKMEB_03609 6.08e-106 - - - - - - - -
LNENKMEB_03610 9.52e-124 ywhD - - S - - - YwhD family
LNENKMEB_03611 2.31e-154 ywhC - - S - - - Peptidase family M50
LNENKMEB_03612 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
LNENKMEB_03613 1.02e-93 ywhA - - K - - - Transcriptional regulator
LNENKMEB_03614 5.69e-315 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
LNENKMEB_03615 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
LNENKMEB_03616 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
LNENKMEB_03617 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
LNENKMEB_03618 2.48e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
LNENKMEB_03619 5.36e-68 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
LNENKMEB_03620 4.59e-121 - - - S - - - membrane
LNENKMEB_03621 8.16e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_03622 1.47e-215 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
LNENKMEB_03625 7.8e-237 - - - - - - - -
LNENKMEB_03627 9.14e-204 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LNENKMEB_03628 2.63e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
LNENKMEB_03629 9.79e-213 - - - S - - - Conserved hypothetical protein 698
LNENKMEB_03630 4.11e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
LNENKMEB_03631 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
LNENKMEB_03632 8.41e-181 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
LNENKMEB_03633 3.14e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
LNENKMEB_03634 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
LNENKMEB_03635 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LNENKMEB_03636 4.65e-180 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LNENKMEB_03637 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LNENKMEB_03638 3.85e-144 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LNENKMEB_03639 1.58e-283 ywfA - - EGP - - - -transporter
LNENKMEB_03640 2.32e-263 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
LNENKMEB_03641 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LNENKMEB_03642 0.0 rocB - - E - - - arginine degradation protein
LNENKMEB_03643 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LNENKMEB_03644 3.15e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LNENKMEB_03645 3.68e-76 - - - - - - - -
LNENKMEB_03646 1.15e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
LNENKMEB_03647 1.93e-207 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LNENKMEB_03648 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LNENKMEB_03649 9.8e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LNENKMEB_03650 2.15e-237 spsG - - M - - - Spore Coat
LNENKMEB_03651 1.38e-171 spsF - - M ko:K07257 - ko00000 Spore Coat
LNENKMEB_03652 1.01e-273 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
LNENKMEB_03653 1.92e-205 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
LNENKMEB_03654 2.16e-283 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
LNENKMEB_03655 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
LNENKMEB_03656 9.06e-184 spsA - - M - - - Spore Coat
LNENKMEB_03657 6.51e-88 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LNENKMEB_03658 1.41e-72 ywdK - - S - - - small membrane protein
LNENKMEB_03659 3.96e-293 ywdJ - - F - - - Xanthine uracil
LNENKMEB_03660 1.57e-62 ywdI - - S - - - Family of unknown function (DUF5327)
LNENKMEB_03661 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LNENKMEB_03662 1.34e-191 ywdF - - S - - - Glycosyltransferase like family 2
LNENKMEB_03664 2e-115 ywdD - - - - - - -
LNENKMEB_03665 1.6e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
LNENKMEB_03666 1.68e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LNENKMEB_03667 3.52e-26 ywdA - - - - - - -
LNENKMEB_03668 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LNENKMEB_03669 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LNENKMEB_03670 1.57e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LNENKMEB_03672 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LNENKMEB_03673 6.66e-236 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LNENKMEB_03674 8.3e-66 - - - L - - - transposase activity
LNENKMEB_03675 6.62e-122 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
LNENKMEB_03676 4.66e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
LNENKMEB_03677 3.11e-270 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LNENKMEB_03678 7.46e-101 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
LNENKMEB_03679 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
LNENKMEB_03680 8.22e-85 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LNENKMEB_03681 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LNENKMEB_03682 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LNENKMEB_03683 2.21e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LNENKMEB_03684 5.74e-48 ydaS - - S - - - membrane
LNENKMEB_03685 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LNENKMEB_03686 2.85e-286 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LNENKMEB_03687 1.71e-81 gtcA - - S - - - GtrA-like protein
LNENKMEB_03688 6.43e-146 - - - K - - - Bacterial regulatory proteins, tetR family
LNENKMEB_03690 7.5e-168 - - - H - - - Methionine biosynthesis protein MetW
LNENKMEB_03691 4.9e-172 - - - S - - - Streptomycin biosynthesis protein StrF
LNENKMEB_03692 5.99e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LNENKMEB_03693 1.54e-309 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
LNENKMEB_03694 9.61e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LNENKMEB_03695 6.45e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LNENKMEB_03696 4.83e-202 ywbI - - K - - - Transcriptional regulator
LNENKMEB_03697 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LNENKMEB_03698 6.47e-144 ywbG - - M - - - effector of murein hydrolase
LNENKMEB_03699 2.61e-37 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
LNENKMEB_03700 4.85e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
LNENKMEB_03701 5.57e-216 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
LNENKMEB_03702 3.08e-286 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
LNENKMEB_03703 1.76e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
LNENKMEB_03704 7.27e-252 - - - L - - - COG3666 Transposase and inactivated derivatives
LNENKMEB_03705 3.28e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LNENKMEB_03706 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LNENKMEB_03707 1.04e-207 gspA - - M - - - General stress
LNENKMEB_03708 4.35e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
LNENKMEB_03709 1.07e-214 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
LNENKMEB_03710 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
LNENKMEB_03711 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LNENKMEB_03712 2.56e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
LNENKMEB_03713 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LNENKMEB_03714 3.76e-290 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LNENKMEB_03715 1.35e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LNENKMEB_03716 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LNENKMEB_03717 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LNENKMEB_03718 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LNENKMEB_03719 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
LNENKMEB_03720 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
LNENKMEB_03721 5.36e-144 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LNENKMEB_03722 7.77e-219 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LNENKMEB_03723 4.83e-231 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LNENKMEB_03724 2.64e-213 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LNENKMEB_03725 1.91e-78 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
LNENKMEB_03726 6.03e-289 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LNENKMEB_03727 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LNENKMEB_03728 7.89e-66 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LNENKMEB_03729 7.31e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LNENKMEB_03730 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LNENKMEB_03731 8.89e-214 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
LNENKMEB_03732 1.02e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LNENKMEB_03733 3.75e-267 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
LNENKMEB_03734 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LNENKMEB_03735 5.33e-244 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
LNENKMEB_03736 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
LNENKMEB_03737 9.85e-198 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LNENKMEB_03738 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
LNENKMEB_03739 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
LNENKMEB_03740 1.36e-242 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
LNENKMEB_03741 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LNENKMEB_03742 1.93e-288 cimH - - C - - - COG3493 Na citrate symporter
LNENKMEB_03743 3.44e-200 yxkH - - G - - - Polysaccharide deacetylase
LNENKMEB_03744 2.51e-259 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LNENKMEB_03745 5.15e-215 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
LNENKMEB_03746 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LNENKMEB_03747 3.12e-119 yxkC - - S - - - Domain of unknown function (DUF4352)
LNENKMEB_03748 1.87e-249 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LNENKMEB_03749 2.22e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LNENKMEB_03752 7.42e-112 yxjI - - S - - - LURP-one-related
LNENKMEB_03753 2.8e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LNENKMEB_03754 3.89e-208 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
LNENKMEB_03755 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LNENKMEB_03756 3.75e-126 - - - T - - - Domain of unknown function (DUF4163)
LNENKMEB_03757 2.38e-65 yxiS - - - - - - -
LNENKMEB_03759 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LNENKMEB_03760 1.57e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LNENKMEB_03761 2.33e-184 bglS - - M - - - licheninase activity
LNENKMEB_03762 1.39e-192 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LNENKMEB_03763 1.82e-282 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
LNENKMEB_03764 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LNENKMEB_03767 9.96e-134 - - - - - - - -
LNENKMEB_03771 2.09e-91 yxiG - - - - - - -
LNENKMEB_03772 4.19e-87 yxxG - - - - - - -
LNENKMEB_03778 5.15e-67 - - - - - - - -
LNENKMEB_03779 0.0 wapA - - M - - - COG3209 Rhs family protein
LNENKMEB_03780 9.42e-258 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
LNENKMEB_03781 8.44e-208 yxxF - - EG - - - EamA-like transporter family
LNENKMEB_03782 4.21e-95 yxiE - - T - - - Belongs to the universal stress protein A family
LNENKMEB_03783 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LNENKMEB_03784 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LNENKMEB_03785 5.09e-60 - - - S - - - Protein of unknown function DUF262
LNENKMEB_03786 2.53e-19 - - - S - - - FRG
LNENKMEB_03787 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LNENKMEB_03788 9.97e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
LNENKMEB_03789 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
LNENKMEB_03790 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LNENKMEB_03791 1.29e-298 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
LNENKMEB_03792 3.38e-225 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LNENKMEB_03793 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LNENKMEB_03794 1.57e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
LNENKMEB_03795 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LNENKMEB_03796 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LNENKMEB_03797 2.88e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LNENKMEB_03798 2.32e-193 yxeH - - S - - - hydrolases of the HAD superfamily
LNENKMEB_03801 2.06e-42 yxeE - - - - - - -
LNENKMEB_03802 5.09e-35 yxeD - - - - - - -
LNENKMEB_03803 2.8e-46 - - - - - - - -
LNENKMEB_03804 1.44e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LNENKMEB_03805 6.96e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
LNENKMEB_03806 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LNENKMEB_03807 3.28e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_03808 7.95e-224 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_03809 3.27e-159 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LNENKMEB_03810 0.0 - - - T - - - Histidine kinase
LNENKMEB_03811 1.57e-176 yvrH - - T - - - Transcriptional regulator
LNENKMEB_03812 1.3e-211 - - - V ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LNENKMEB_03813 1.36e-167 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 permease
LNENKMEB_03814 1.28e-168 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LNENKMEB_03815 3.3e-203 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LNENKMEB_03816 1.03e-201 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LNENKMEB_03817 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
LNENKMEB_03818 5.4e-252 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LNENKMEB_03819 1.82e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
LNENKMEB_03820 1.61e-223 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LNENKMEB_03821 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LNENKMEB_03822 2.92e-233 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LNENKMEB_03823 6.21e-203 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LNENKMEB_03824 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LNENKMEB_03825 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LNENKMEB_03826 1.43e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
LNENKMEB_03827 1.1e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LNENKMEB_03828 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
LNENKMEB_03830 2.06e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LNENKMEB_03831 1.07e-131 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LNENKMEB_03832 2.38e-254 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_03833 1.23e-255 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
LNENKMEB_03834 1.14e-276 yxbF - - K - - - Bacterial regulatory proteins, tetR family
LNENKMEB_03835 0.0 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LNENKMEB_03836 1.45e-190 yxaL - - S - - - PQQ-like domain
LNENKMEB_03837 1.02e-84 - - - S - - - Family of unknown function (DUF5391)
LNENKMEB_03838 2.01e-66 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LNENKMEB_03839 5.4e-256 - - - EGP - - - Major Facilitator Superfamily
LNENKMEB_03840 7.8e-97 yxaI - - S - - - membrane protein domain
LNENKMEB_03841 5.45e-162 - - - E - - - Ring-cleavage extradiol dioxygenase
LNENKMEB_03842 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
LNENKMEB_03843 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
LNENKMEB_03844 4.61e-291 - - - S - - - Fic/DOC family
LNENKMEB_03845 5.26e-314 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LNENKMEB_03846 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
LNENKMEB_03847 9.14e-110 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LNENKMEB_03848 2.23e-196 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LNENKMEB_03849 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LNENKMEB_03850 6.91e-115 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
LNENKMEB_03851 1.98e-235 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LNENKMEB_03852 4.8e-229 - - - S - - - Fusaric acid resistance protein-like
LNENKMEB_03853 7.34e-26 - - - - - - - -
LNENKMEB_03854 2.58e-141 - - - D - - - AAA domain
LNENKMEB_03855 9.83e-17 - - - S - - - Restriction endonuclease
LNENKMEB_03857 1.43e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LNENKMEB_03861 6.89e-279 yycP - - - - - - -
LNENKMEB_03862 7.96e-170 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LNENKMEB_03863 3.7e-234 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
LNENKMEB_03864 6.61e-110 yycN - - K - - - Acetyltransferase
LNENKMEB_03866 3.7e-259 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
LNENKMEB_03867 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LNENKMEB_03868 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LNENKMEB_03869 6.81e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
LNENKMEB_03870 3.8e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
LNENKMEB_03871 2.69e-57 sdpR - - K - - - transcriptional
LNENKMEB_03872 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LNENKMEB_03873 1.3e-188 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
LNENKMEB_03874 0.0 - - - S - - - ABC transporter
LNENKMEB_03875 6.06e-257 - - - S - - - Major Facilitator Superfamily
LNENKMEB_03876 0.0 - - - - - - - -
LNENKMEB_03877 9e-241 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
LNENKMEB_03878 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LNENKMEB_03879 1.22e-14 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LNENKMEB_03880 1.63e-278 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LNENKMEB_03881 9.84e-192 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LNENKMEB_03882 2.4e-195 yycI - - S - - - protein conserved in bacteria
LNENKMEB_03883 0.0 yycH - - S - - - protein conserved in bacteria
LNENKMEB_03884 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LNENKMEB_03885 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LNENKMEB_03890 1.06e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LNENKMEB_03891 1.63e-96 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LNENKMEB_03892 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LNENKMEB_03893 2.21e-38 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
LNENKMEB_03895 3.6e-25 yycC - - K - - - YycC-like protein
LNENKMEB_03896 1.26e-305 - - - M - - - Glycosyltransferase Family 4
LNENKMEB_03897 5.03e-256 - - - S - - - Ecdysteroid kinase
LNENKMEB_03898 3.12e-295 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
LNENKMEB_03899 5.47e-298 - - - M - - - Glycosyltransferase Family 4
LNENKMEB_03900 1.25e-156 - - - S - - - GlcNAc-PI de-N-acetylase
LNENKMEB_03901 4.67e-155 - - - KLT - - - COG0515 Serine threonine protein kinase
LNENKMEB_03902 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LNENKMEB_03903 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LNENKMEB_03904 7.12e-204 yybS - - S - - - membrane
LNENKMEB_03906 1.27e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
LNENKMEB_03907 4.56e-87 yybR - - K - - - Transcriptional regulator
LNENKMEB_03908 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
LNENKMEB_03909 2.05e-197 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LNENKMEB_03910 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
LNENKMEB_03911 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
LNENKMEB_03912 1.33e-149 - - - K - - - FCD domain
LNENKMEB_03913 2.25e-116 - - - S - - - PFAM DinB family protein
LNENKMEB_03914 1.41e-205 - - - G - - - Major Facilitator Superfamily
LNENKMEB_03915 2.06e-202 - - - K - - - LysR substrate binding domain
LNENKMEB_03916 3.78e-128 - - - E - - - LysE type translocator
LNENKMEB_03917 1.94e-74 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
LNENKMEB_03918 1.7e-148 ydgI - - C - - - nitroreductase
LNENKMEB_03919 1.37e-89 - - - K - - - Winged helix DNA-binding domain
LNENKMEB_03920 1.38e-196 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LNENKMEB_03921 1.3e-99 yybA - - K - - - transcriptional
LNENKMEB_03922 1.89e-100 yjcF - - S - - - Acetyltransferase (GNAT) domain
LNENKMEB_03923 2.02e-212 - - - M - - - Domain of Unknown Function (DUF1259)
LNENKMEB_03924 2.02e-88 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
LNENKMEB_03925 4.21e-212 - - - K - - - Transcriptional regulator
LNENKMEB_03926 3.79e-182 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LNENKMEB_03927 4.3e-312 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LNENKMEB_03928 4.96e-164 - - - EG - - - EamA-like transporter family
LNENKMEB_03929 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
LNENKMEB_03930 3.6e-211 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
LNENKMEB_03931 1.88e-316 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
LNENKMEB_03932 8.1e-87 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LNENKMEB_03933 6.9e-232 ccpB - - K - - - Transcriptional regulator
LNENKMEB_03934 1.98e-185 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LNENKMEB_03935 5.84e-129 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LNENKMEB_03936 4.41e-137 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
LNENKMEB_03937 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LNENKMEB_03938 4.77e-99 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LNENKMEB_03939 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LNENKMEB_03940 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LNENKMEB_03941 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LNENKMEB_03942 1.82e-45 yyzM - - S - - - protein conserved in bacteria
LNENKMEB_03943 3.36e-225 yyaD - - S - - - Membrane
LNENKMEB_03944 6.7e-108 yhhY - - K - - - FR47-like protein
LNENKMEB_03945 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
LNENKMEB_03946 1.43e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LNENKMEB_03947 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
LNENKMEB_03948 6.61e-195 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LNENKMEB_03949 7.99e-165 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LNENKMEB_03950 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LNENKMEB_03951 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LNENKMEB_03952 2.3e-142 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
LNENKMEB_03953 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LNENKMEB_03954 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LNENKMEB_03955 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LNENKMEB_03956 3.45e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LNENKMEB_03957 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
LNENKMEB_03958 3.2e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LNENKMEB_03959 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
LNENKMEB_03960 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LNENKMEB_03961 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LNENKMEB_03962 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LNENKMEB_03965 8.24e-234 yaaC - - S - - - YaaC-like Protein
LNENKMEB_03966 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LNENKMEB_03967 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LNENKMEB_03968 2.61e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LNENKMEB_03969 2.86e-139 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LNENKMEB_03970 1.59e-285 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LNENKMEB_03971 1.2e-260 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LNENKMEB_03973 1.25e-157 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
LNENKMEB_03974 4.04e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
LNENKMEB_03975 1.01e-277 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
LNENKMEB_03976 8.32e-128 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
LNENKMEB_03977 2.89e-110 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LNENKMEB_03978 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LNENKMEB_03979 2.41e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LNENKMEB_03980 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LNENKMEB_03981 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
LNENKMEB_03982 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
LNENKMEB_03983 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)