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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HGNGGLLK_00001	4.28e-274	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HGNGGLLK_00002	1.25e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HGNGGLLK_00003	5.66e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
HGNGGLLK_00004	1.05e-36	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HGNGGLLK_00005	3.06e-150	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HGNGGLLK_00006	2.3e-174	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HGNGGLLK_00007	1.55e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HGNGGLLK_00008	6.34e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HGNGGLLK_00009	3.4e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HGNGGLLK_00010	6.84e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HGNGGLLK_00011	5.35e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HGNGGLLK_00012	2.7e-185	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HGNGGLLK_00013	1.17e-173	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HGNGGLLK_00014	8.02e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HGNGGLLK_00015	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HGNGGLLK_00016	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGNGGLLK_00017	3.26e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HGNGGLLK_00018	2.39e-175	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HGNGGLLK_00019	1.74e-264	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HGNGGLLK_00020	4.99e-251	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HGNGGLLK_00021	4.36e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HGNGGLLK_00022	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HGNGGLLK_00023	8.99e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HGNGGLLK_00024	6.7e-283	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HGNGGLLK_00025	3.71e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HGNGGLLK_00026	5.5e-67	ylxQ	-	-	J	-	-	-	ribosomal protein
HGNGGLLK_00027	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HGNGGLLK_00028	1.49e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HGNGGLLK_00029	3.76e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HGNGGLLK_00030	2.15e-235	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HGNGGLLK_00031	9e-317	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HGNGGLLK_00032	1.49e-74	-	-	-	L	-	-	-	Helix-turn-helix domain
HGNGGLLK_00033	4.4e-25	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_00034	4.19e-152	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_00035	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HGNGGLLK_00036	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HGNGGLLK_00037	2.2e-227	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HGNGGLLK_00038	1.37e-196	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HGNGGLLK_00040	2.17e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HGNGGLLK_00042	9.26e-289	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00043	8.57e-216	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HGNGGLLK_00044	1.84e-238	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGNGGLLK_00045	1.39e-31	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HGNGGLLK_00046	4.95e-123	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HGNGGLLK_00049	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HGNGGLLK_00050	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HGNGGLLK_00051	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HGNGGLLK_00052	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
HGNGGLLK_00053	7.34e-217	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HGNGGLLK_00054	1.35e-164	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_00055	3.87e-80	-	-	-	-	-	-	-	-
HGNGGLLK_00056	1.21e-244	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HGNGGLLK_00057	5.35e-84	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HGNGGLLK_00058	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HGNGGLLK_00059	9.95e-267	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HGNGGLLK_00060	6.5e-123	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HGNGGLLK_00061	2.15e-11	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HGNGGLLK_00062	1.34e-62	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HGNGGLLK_00063	2.55e-215	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HGNGGLLK_00064	1.01e-275	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HGNGGLLK_00065	5.28e-139	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HGNGGLLK_00066	2.12e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HGNGGLLK_00067	5.12e-132	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HGNGGLLK_00068	1.21e-143	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HGNGGLLK_00069	2.29e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HGNGGLLK_00070	2.58e-181	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HGNGGLLK_00071	5.32e-73	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HGNGGLLK_00072	2.63e-69	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HGNGGLLK_00073	2.58e-254	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HGNGGLLK_00074	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HGNGGLLK_00075	1.35e-164	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_00077	3.72e-145	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HGNGGLLK_00078	9.45e-07	-	-	-	C	-	-	-	aldo keto reductase
HGNGGLLK_00079	2.97e-105	-	-	-	C	-	-	-	aldo keto reductase
HGNGGLLK_00080	7.18e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HGNGGLLK_00081	8.79e-284	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGNGGLLK_00082	0.0	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HGNGGLLK_00083	7.88e-103	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
HGNGGLLK_00084	1.14e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HGNGGLLK_00085	4.58e-289	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HGNGGLLK_00086	1.25e-136	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HGNGGLLK_00087	2.81e-258	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HGNGGLLK_00088	2.05e-45	-	-	-	C	-	-	-	Flavodoxin
HGNGGLLK_00089	7.77e-198	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_00090	1.06e-72	-	-	-	L	-	-	-	Helix-turn-helix domain
HGNGGLLK_00091	2.67e-272	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HGNGGLLK_00092	5.34e-29	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_00093	5.5e-302	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_00094	3.32e-28	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HGNGGLLK_00095	1.21e-240	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HGNGGLLK_00096	7.8e-282	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HGNGGLLK_00098	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_00099	1.7e-183	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_00100	7.93e-65	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_00101	3.14e-132	cadD	-	-	P	-	-	-	Cadmium resistance transporter
HGNGGLLK_00102	1.55e-151	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HGNGGLLK_00103	5.05e-136	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGNGGLLK_00104	4.89e-201	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HGNGGLLK_00105	1.3e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGNGGLLK_00106	2.75e-05	-	-	-	K	-	-	-	LysR substrate binding domain
HGNGGLLK_00107	2.51e-133	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HGNGGLLK_00108	8.45e-97	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HGNGGLLK_00109	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
HGNGGLLK_00110	5.84e-269	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HGNGGLLK_00111	2.87e-52	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HGNGGLLK_00112	2.94e-89	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HGNGGLLK_00113	6.81e-192	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HGNGGLLK_00114	1.76e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HGNGGLLK_00115	1.1e-184	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HGNGGLLK_00116	6.34e-182	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HGNGGLLK_00117	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGNGGLLK_00118	2.16e-114	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
HGNGGLLK_00119	3.17e-126	-	-	-	L	-	-	-	restriction endonuclease
HGNGGLLK_00120	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
HGNGGLLK_00121	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HGNGGLLK_00122	3.28e-196	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00123	2.12e-74	-	-	-	L	-	-	-	Helix-turn-helix domain
HGNGGLLK_00124	5.4e-22	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_00125	1.7e-151	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_00126	1.67e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HGNGGLLK_00128	3.97e-71	-	-	-	-	-	-	-	-
HGNGGLLK_00129	3.62e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HGNGGLLK_00130	1.05e-174	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HGNGGLLK_00131	1.72e-75	-	-	-	-	-	-	-	-
HGNGGLLK_00132	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HGNGGLLK_00133	8.94e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HGNGGLLK_00134	1.01e-108	-	-	-	K	-	-	-	Transcriptional regulator
HGNGGLLK_00135	6.92e-280	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HGNGGLLK_00136	4.6e-271	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HGNGGLLK_00138	3.96e-146	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HGNGGLLK_00139	3.24e-147	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
HGNGGLLK_00140	3.4e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_00141	2.14e-196	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HGNGGLLK_00142	1.02e-225	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HGNGGLLK_00143	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_00144	2.55e-38	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_00145	2.12e-234	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_00146	1.05e-16	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HGNGGLLK_00147	1.85e-201	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HGNGGLLK_00148	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HGNGGLLK_00149	6.48e-87	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HGNGGLLK_00150	2.94e-211	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HGNGGLLK_00151	1.08e-214	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HGNGGLLK_00152	4.96e-223	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
HGNGGLLK_00153	2.99e-248	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HGNGGLLK_00154	1.62e-313	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HGNGGLLK_00155	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HGNGGLLK_00156	1.83e-164	-	-	-	F	-	-	-	glutamine amidotransferase
HGNGGLLK_00157	3.81e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HGNGGLLK_00158	7.23e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HGNGGLLK_00159	3.02e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HGNGGLLK_00160	2.91e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HGNGGLLK_00161	7.64e-88	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HGNGGLLK_00162	8.91e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HGNGGLLK_00163	1.52e-199	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HGNGGLLK_00164	1.03e-239	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HGNGGLLK_00165	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HGNGGLLK_00166	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HGNGGLLK_00167	1.21e-264	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HGNGGLLK_00168	2.71e-96	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
HGNGGLLK_00169	2.18e-162	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_00170	6.27e-109	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_00171	1.94e-92	is18	-	-	L	-	-	-	Integrase core domain
HGNGGLLK_00172	1.44e-51	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HGNGGLLK_00173	3.87e-114	-	-	-	-	-	-	-	-
HGNGGLLK_00174	3.37e-96	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HGNGGLLK_00175	1.19e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
HGNGGLLK_00176	4.74e-23	-	-	-	-	-	-	-	-
HGNGGLLK_00177	1.28e-313	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGNGGLLK_00178	2.02e-215	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HGNGGLLK_00179	8.7e-233	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HGNGGLLK_00180	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HGNGGLLK_00181	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HGNGGLLK_00182	5.23e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HGNGGLLK_00183	4.67e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HGNGGLLK_00184	1.09e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGNGGLLK_00185	5.43e-182	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HGNGGLLK_00186	3.98e-277	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HGNGGLLK_00187	1.28e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HGNGGLLK_00188	3.38e-293	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HGNGGLLK_00189	3.26e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HGNGGLLK_00190	8.01e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HGNGGLLK_00191	2e-200	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HGNGGLLK_00192	5.08e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HGNGGLLK_00194	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HGNGGLLK_00195	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HGNGGLLK_00196	6.26e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HGNGGLLK_00197	8.52e-175	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HGNGGLLK_00198	2.23e-89	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGNGGLLK_00199	3.39e-182	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HGNGGLLK_00200	3.2e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HGNGGLLK_00201	1.44e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HGNGGLLK_00202	2.03e-112	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HGNGGLLK_00203	1.56e-253	-	-	-	S	-	-	-	Helix-turn-helix domain
HGNGGLLK_00204	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HGNGGLLK_00205	4.37e-76	-	-	-	M	-	-	-	Lysin motif
HGNGGLLK_00206	2.29e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HGNGGLLK_00207	4.63e-275	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HGNGGLLK_00208	1.29e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HGNGGLLK_00209	2.65e-53	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HGNGGLLK_00210	2.52e-300	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HGNGGLLK_00211	1.29e-211	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HGNGGLLK_00212	1.2e-281	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HGNGGLLK_00213	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_00214	5.32e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HGNGGLLK_00215	4.4e-122	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HGNGGLLK_00216	8.06e-141	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HGNGGLLK_00217	2.23e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HGNGGLLK_00218	2.06e-278	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
HGNGGLLK_00219	1.2e-146	cat	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
HGNGGLLK_00220	2.46e-217	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HGNGGLLK_00221	2.85e-135	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HGNGGLLK_00222	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HGNGGLLK_00223	1.85e-214	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGNGGLLK_00224	5.62e-86	-	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HGNGGLLK_00225	1.38e-82	-	-	-	S	-	-	-	Arsenical resistance operon trans-acting repressor ArsD
HGNGGLLK_00226	0.0	arsA	3.6.3.16	-	D	ko:K01551	-	ko00000,ko01000,ko02000	Anion-transporting ATPase
HGNGGLLK_00227	4.48e-295	arsB	-	-	U	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HGNGGLLK_00228	5.45e-68	-	-	-	-	-	-	-	-
HGNGGLLK_00229	4.76e-290	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_00230	1.56e-163	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_00231	0.0	nox	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HGNGGLLK_00232	1.77e-174	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00233	3.02e-61	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00234	4.58e-82	-	-	-	K	-	-	-	Transcriptional regulator
HGNGGLLK_00235	2.21e-131	cadD	-	-	P	-	-	-	Cadmium resistance transporter
HGNGGLLK_00236	2.21e-160	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_00237	7.61e-18	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HGNGGLLK_00238	6.28e-98	-	-	-	K	ko:K07467	-	ko00000	Replication initiation factor
HGNGGLLK_00239	1.02e-30	-	-	-	-	-	-	-	-
HGNGGLLK_00240	1.03e-124	-	-	-	L	-	-	-	DNA integration
HGNGGLLK_00241	4.46e-32	-	-	-	GM	-	-	-	NmrA-like family
HGNGGLLK_00242	8.96e-20	-	-	-	GM	-	-	-	NAD(P)H-binding
HGNGGLLK_00245	1.1e-26	-	-	-	L	ko:K07459	-	ko00000	AAA ATPase domain
HGNGGLLK_00247	3.83e-163	-	-	-	L	-	-	-	Integrase core domain
HGNGGLLK_00248	4.06e-58	-	-	-	-	-	-	-	-
HGNGGLLK_00249	8.09e-42	-	-	-	-	-	-	-	-
HGNGGLLK_00250	8.56e-78	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HGNGGLLK_00252	5.47e-79	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HGNGGLLK_00253	1.17e-253	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HGNGGLLK_00254	1.31e-25	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HGNGGLLK_00255	1.27e-89	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HGNGGLLK_00256	6.31e-97	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HGNGGLLK_00257	0.000351	-	-	-	K	-	-	-	Transcriptional
HGNGGLLK_00258	4.14e-135	-	-	-	K	ko:K07467	-	ko00000	Replication initiation factor
HGNGGLLK_00259	1.98e-39	-	-	-	-	-	-	-	-
HGNGGLLK_00260	3.25e-132	-	-	-	L	-	-	-	DNA integration
HGNGGLLK_00261	1.71e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HGNGGLLK_00262	4.82e-179	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGNGGLLK_00263	5.14e-212	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HGNGGLLK_00264	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGNGGLLK_00265	3.18e-198	-	-	-	D	-	-	-	DNA integration
HGNGGLLK_00266	9.3e-220	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HGNGGLLK_00267	2.14e-133	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HGNGGLLK_00268	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGNGGLLK_00269	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGNGGLLK_00270	4.2e-122	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HGNGGLLK_00271	5.36e-219	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HGNGGLLK_00272	7.86e-92	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HGNGGLLK_00273	4.65e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HGNGGLLK_00274	3.6e-122	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HGNGGLLK_00275	5.48e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HGNGGLLK_00276	7.19e-314	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HGNGGLLK_00277	3.75e-307	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
HGNGGLLK_00278	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
HGNGGLLK_00280	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HGNGGLLK_00281	2.68e-152	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HGNGGLLK_00282	4.3e-312	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HGNGGLLK_00283	6.21e-21	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HGNGGLLK_00284	5.56e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_00285	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
HGNGGLLK_00286	5.43e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HGNGGLLK_00287	6.07e-138	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HGNGGLLK_00288	2.77e-10	-	-	-	C	-	-	-	Domain of unknown function (DUF4145)
HGNGGLLK_00289	4.79e-291	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00290	5.34e-89	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HGNGGLLK_00291	2.81e-117	-	-	-	S	-	-	-	Fic/DOC family
HGNGGLLK_00292	1.32e-125	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HGNGGLLK_00293	6.8e-154	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HGNGGLLK_00294	7.86e-118	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HGNGGLLK_00295	1.46e-88	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HGNGGLLK_00296	2.89e-136	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HGNGGLLK_00297	1.28e-274	-	-	-	E	-	-	-	Aminotransferase
HGNGGLLK_00300	3.03e-44	-	-	-	S	-	-	-	Phage minor capsid protein 2
HGNGGLLK_00301	9.86e-93	-	-	-	S	-	-	-	Phage minor capsid protein 2
HGNGGLLK_00302	1.82e-209	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HGNGGLLK_00303	5.49e-124	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HGNGGLLK_00305	5.05e-207	-	-	-	S	-	-	-	DUF218 domain
HGNGGLLK_00306	8.03e-214	yvgN	-	-	C	-	-	-	Aldo keto reductase
HGNGGLLK_00307	1.85e-105	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HGNGGLLK_00308	1.57e-194	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HGNGGLLK_00309	1.46e-302	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
HGNGGLLK_00310	1.08e-78	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HGNGGLLK_00311	7.19e-260	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HGNGGLLK_00312	2.4e-230	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HGNGGLLK_00313	4.21e-287	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HGNGGLLK_00314	3.37e-249	bdhA	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HGNGGLLK_00315	3.35e-89	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HGNGGLLK_00316	2.04e-74	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HGNGGLLK_00317	7.95e-132	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HGNGGLLK_00318	1.33e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_00319	1.8e-138	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HGNGGLLK_00320	2.84e-209	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
HGNGGLLK_00321	1.21e-99	ywnA	-	-	K	-	-	-	Transcriptional regulator
HGNGGLLK_00322	5.23e-97	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
HGNGGLLK_00323	3.92e-97	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HGNGGLLK_00324	2.66e-33	-	-	-	C	-	-	-	Flavodoxin
HGNGGLLK_00325	1.39e-39	-	-	-	GM	-	-	-	NmrA-like family
HGNGGLLK_00326	4.58e-59	-	-	-	K	-	-	-	transcriptional regulator
HGNGGLLK_00327	6.26e-138	-	-	-	L	-	-	-	Integrase
HGNGGLLK_00328	1.51e-88	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HGNGGLLK_00329	1.09e-169	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HGNGGLLK_00330	3.41e-16	citR	-	-	K	-	-	-	sugar-binding domain protein
HGNGGLLK_00331	1.6e-77	citR	-	-	K	-	-	-	sugar-binding domain protein
HGNGGLLK_00332	2.44e-233	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HGNGGLLK_00334	1.89e-205	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HGNGGLLK_00335	1.01e-98	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGNGGLLK_00336	6.51e-45	-	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HGNGGLLK_00337	1.34e-74	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
HGNGGLLK_00338	1.2e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HGNGGLLK_00339	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HGNGGLLK_00340	3.39e-275	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HGNGGLLK_00341	1.07e-264	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HGNGGLLK_00342	3.76e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HGNGGLLK_00343	9.58e-214	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HGNGGLLK_00344	1.65e-53	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HGNGGLLK_00345	2.21e-310	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HGNGGLLK_00346	5.37e-230	-	-	-	K	-	-	-	WYL domain
HGNGGLLK_00347	2.29e-88	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HGNGGLLK_00348	7.18e-45	-	-	-	-	-	-	-	-
HGNGGLLK_00350	2.65e-84	-	-	-	-	-	-	-	-
HGNGGLLK_00352	4.24e-80	yicL	-	-	EG	-	-	-	EamA-like transporter family
HGNGGLLK_00353	5.01e-12	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HGNGGLLK_00354	1.37e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HGNGGLLK_00355	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HGNGGLLK_00356	6.15e-211	-	-	-	K	-	-	-	LysR substrate binding domain
HGNGGLLK_00357	2.34e-205	rssA	-	-	S	-	-	-	Phospholipase, patatin family
HGNGGLLK_00358	1.33e-273	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HGNGGLLK_00359	5.43e-238	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
HGNGGLLK_00360	1.2e-158	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HGNGGLLK_00361	8.23e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HGNGGLLK_00362	2.89e-250	flp	-	-	V	-	-	-	Beta-lactamase
HGNGGLLK_00363	1.13e-290	-	-	-	-	-	-	-	-
HGNGGLLK_00365	1.25e-205	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HGNGGLLK_00366	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGNGGLLK_00367	4.05e-211	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HGNGGLLK_00368	3.89e-209	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HGNGGLLK_00369	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HGNGGLLK_00371	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HGNGGLLK_00373	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HGNGGLLK_00374	1.84e-302	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HGNGGLLK_00375	4.81e-08	-	-	-	S	-	-	-	SNARE associated Golgi protein
HGNGGLLK_00376	3.37e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HGNGGLLK_00377	8.73e-129	-	-	-	K	-	-	-	Virulence activator alpha C-term
HGNGGLLK_00378	1.26e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HGNGGLLK_00380	2.5e-282	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HGNGGLLK_00382	3.12e-185	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HGNGGLLK_00383	2.92e-197	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HGNGGLLK_00384	9.94e-287	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HGNGGLLK_00385	5.61e-41	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HGNGGLLK_00386	1.37e-131	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HGNGGLLK_00387	5.19e-48	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HGNGGLLK_00388	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HGNGGLLK_00389	2.8e-276	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HGNGGLLK_00392	7.69e-74	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
HGNGGLLK_00393	4.91e-84	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HGNGGLLK_00394	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_00395	1.16e-303	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_00396	9.68e-50	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HGNGGLLK_00397	1.82e-59	yrfB	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HGNGGLLK_00398	5.2e-89	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HGNGGLLK_00399	1.87e-171	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HGNGGLLK_00400	2.92e-145	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_00401	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HGNGGLLK_00402	4.76e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
HGNGGLLK_00404	3.64e-113	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_00405	1.28e-53	-	-	-	L	-	-	-	Helix-turn-helix domain
HGNGGLLK_00406	4.54e-25	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HGNGGLLK_00407	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HGNGGLLK_00410	7.93e-290	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00411	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HGNGGLLK_00414	2.4e-60	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00416	3.37e-291	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00417	5.77e-72	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
HGNGGLLK_00418	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
HGNGGLLK_00420	3.56e-130	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HGNGGLLK_00421	1.77e-174	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00422	3.02e-61	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00424	9.64e-109	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00425	3.98e-82	-	-	-	L	-	-	-	Integrase core domain
HGNGGLLK_00426	3.98e-129	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HGNGGLLK_00427	2.14e-34	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGNGGLLK_00428	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HGNGGLLK_00429	3.98e-29	yvcC	-	-	M	-	-	-	Cna protein B-type domain
HGNGGLLK_00430	1.54e-246	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HGNGGLLK_00431	1.22e-84	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HGNGGLLK_00432	1.25e-05	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_00433	5.74e-34	is18	-	-	L	-	-	-	Integrase core domain
HGNGGLLK_00434	1.88e-60	repA	-	-	S	-	-	-	Replication initiator protein A
HGNGGLLK_00435	6.33e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGNGGLLK_00436	2.87e-71	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGNGGLLK_00437	2.51e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGNGGLLK_00438	6.33e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HGNGGLLK_00439	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HGNGGLLK_00440	5.02e-165	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
HGNGGLLK_00441	3.88e-106	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_00442	1.74e-176	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_00443	3.93e-290	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00444	1.92e-213	-	-	-	GK	-	-	-	ROK family
HGNGGLLK_00445	1.12e-54	-	-	-	-	-	-	-	-
HGNGGLLK_00446	1.03e-106	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HGNGGLLK_00448	5.17e-100	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
HGNGGLLK_00449	1.04e-218	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
HGNGGLLK_00450	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HGNGGLLK_00451	2.34e-301	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HGNGGLLK_00452	8.05e-233	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
HGNGGLLK_00453	1.59e-80	-	-	-	-	-	-	-	-
HGNGGLLK_00454	4.2e-284	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HGNGGLLK_00455	1.69e-124	-	-	-	V	-	-	-	VanZ like family
HGNGGLLK_00456	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HGNGGLLK_00457	7.88e-62	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HGNGGLLK_00458	1.52e-82	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HGNGGLLK_00459	1.01e-99	-	-	-	-	-	-	-	-
HGNGGLLK_00460	1.24e-234	-	-	-	-	-	-	-	-
HGNGGLLK_00461	7.16e-163	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
HGNGGLLK_00462	1.77e-131	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	Nitrate reductase delta subunit
HGNGGLLK_00463	0.0	-	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HGNGGLLK_00464	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGNGGLLK_00465	6.23e-244	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HGNGGLLK_00466	2.18e-112	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HGNGGLLK_00467	3.66e-294	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
HGNGGLLK_00468	5.7e-108	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HGNGGLLK_00469	1.01e-127	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HGNGGLLK_00470	6.94e-54	-	-	-	-	-	-	-	-
HGNGGLLK_00471	8.62e-102	nreA	-	-	T	ko:K10851	ko02020,map02020	ko00000,ko00001	GAF domain
HGNGGLLK_00472	1.14e-239	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
HGNGGLLK_00473	1.83e-150	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HGNGGLLK_00474	1.99e-53	-	-	-	-	-	-	-	-
HGNGGLLK_00475	1.7e-235	-	-	-	-	-	-	-	-
HGNGGLLK_00476	3.49e-217	-	-	-	H	-	-	-	geranyltranstransferase activity
HGNGGLLK_00478	2.5e-172	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HGNGGLLK_00479	4.73e-210	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HGNGGLLK_00480	2.36e-77	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HGNGGLLK_00481	7.73e-277	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
HGNGGLLK_00482	1.67e-249	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HGNGGLLK_00483	2.34e-47	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
HGNGGLLK_00484	7.91e-95	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HGNGGLLK_00485	8.22e-76	-	-	-	S	-	-	-	Flavodoxin
HGNGGLLK_00486	5.1e-219	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGNGGLLK_00487	2.6e-183	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HGNGGLLK_00488	1.55e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HGNGGLLK_00489	3.62e-72	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HGNGGLLK_00490	1.04e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF1858)
HGNGGLLK_00491	0.0	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HGNGGLLK_00492	9.64e-183	-	-	-	EG	-	-	-	EamA-like transporter family
HGNGGLLK_00493	5.13e-244	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HGNGGLLK_00494	4.1e-310	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGNGGLLK_00495	5.13e-244	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HGNGGLLK_00496	7.17e-237	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HGNGGLLK_00497	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HGNGGLLK_00498	5.04e-109	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HGNGGLLK_00499	2.6e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGNGGLLK_00500	1.09e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HGNGGLLK_00501	2.21e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HGNGGLLK_00502	8.17e-45	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HGNGGLLK_00503	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HGNGGLLK_00504	1.25e-31	-	-	-	S	-	-	-	Virus attachment protein p12 family
HGNGGLLK_00505	6.35e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HGNGGLLK_00506	2.2e-227	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HGNGGLLK_00507	2.41e-235	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGNGGLLK_00508	6.11e-277	aspB3	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
HGNGGLLK_00509	7.49e-117	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HGNGGLLK_00510	7.09e-252	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HGNGGLLK_00511	3.33e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HGNGGLLK_00512	9.4e-133	-	-	-	-	-	-	-	-
HGNGGLLK_00513	7.65e-272	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HGNGGLLK_00514	7.56e-15	aroH	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
HGNGGLLK_00515	2.47e-273	-	-	-	G	-	-	-	Major Facilitator Superfamily
HGNGGLLK_00517	5.39e-46	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HGNGGLLK_00518	4.65e-252	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HGNGGLLK_00521	2.24e-196	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HGNGGLLK_00522	1.3e-203	-	-	-	GM	-	-	-	NAD(P)H-binding
HGNGGLLK_00523	4.02e-201	-	-	-	S	-	-	-	Alpha beta hydrolase
HGNGGLLK_00524	7.97e-301	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HGNGGLLK_00526	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HGNGGLLK_00527	1.56e-42	-	-	-	-	-	-	-	-
HGNGGLLK_00528	1.92e-302	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_00529	6e-100	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_00530	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HGNGGLLK_00532	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HGNGGLLK_00533	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HGNGGLLK_00534	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HGNGGLLK_00535	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HGNGGLLK_00536	3.73e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HGNGGLLK_00537	2.36e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGNGGLLK_00538	3.52e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGNGGLLK_00539	1.53e-214	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HGNGGLLK_00540	7.61e-203	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
HGNGGLLK_00541	1.8e-271	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HGNGGLLK_00542	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HGNGGLLK_00543	1.27e-271	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
HGNGGLLK_00544	7.1e-59	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
HGNGGLLK_00545	3.33e-42	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
HGNGGLLK_00546	4.99e-274	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HGNGGLLK_00547	1.67e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HGNGGLLK_00548	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HGNGGLLK_00549	1.3e-270	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGNGGLLK_00550	6.09e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HGNGGLLK_00551	4.9e-232	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HGNGGLLK_00552	7.76e-72	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
HGNGGLLK_00553	1.63e-156	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
HGNGGLLK_00554	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HGNGGLLK_00555	1.24e-298	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HGNGGLLK_00556	1.15e-201	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HGNGGLLK_00557	8.44e-128	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HGNGGLLK_00558	1.24e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HGNGGLLK_00559	1.24e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HGNGGLLK_00560	8.3e-171	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HGNGGLLK_00561	8.01e-129	-	-	-	-	-	-	-	-
HGNGGLLK_00562	6.96e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
HGNGGLLK_00563	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HGNGGLLK_00564	2e-304	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_00565	1.06e-17	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_00566	9.62e-276	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_00567	4.36e-155	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HGNGGLLK_00568	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HGNGGLLK_00569	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HGNGGLLK_00570	4.45e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HGNGGLLK_00571	1.27e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HGNGGLLK_00572	8.6e-93	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HGNGGLLK_00573	4.95e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HGNGGLLK_00574	1.85e-137	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HGNGGLLK_00575	1.45e-200	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HGNGGLLK_00576	6.51e-150	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HGNGGLLK_00577	3.65e-05	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HGNGGLLK_00578	4.79e-291	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00579	1.51e-11	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGNGGLLK_00580	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HGNGGLLK_00581	1.06e-254	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HGNGGLLK_00582	1.88e-243	arcT	-	-	E	-	-	-	Dipeptidase
HGNGGLLK_00583	1.28e-278	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HGNGGLLK_00584	9.95e-108	-	-	-	F	-	-	-	Hydrolase, NUDIX family
HGNGGLLK_00585	9.84e-268	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
HGNGGLLK_00586	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HGNGGLLK_00587	2.08e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HGNGGLLK_00588	6e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HGNGGLLK_00589	5.72e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HGNGGLLK_00590	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HGNGGLLK_00591	1.9e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HGNGGLLK_00592	3.33e-243	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HGNGGLLK_00593	5.43e-190	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HGNGGLLK_00594	4.14e-173	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HGNGGLLK_00595	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HGNGGLLK_00596	6.4e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HGNGGLLK_00597	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HGNGGLLK_00598	3.08e-214	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HGNGGLLK_00599	1.75e-229	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HGNGGLLK_00600	3.91e-269	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HGNGGLLK_00601	2.15e-262	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HGNGGLLK_00602	2.27e-119	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGNGGLLK_00603	1.86e-130	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HGNGGLLK_00604	2.42e-122	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HGNGGLLK_00605	2.23e-116	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HGNGGLLK_00606	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HGNGGLLK_00607	4.35e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HGNGGLLK_00608	1.12e-213	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HGNGGLLK_00609	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HGNGGLLK_00610	6.95e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HGNGGLLK_00611	3.65e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HGNGGLLK_00612	9.39e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HGNGGLLK_00613	9.4e-45	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
HGNGGLLK_00614	3.39e-60	-	-	-	L	ko:K07483	-	ko00000	Transposase
HGNGGLLK_00615	5.19e-163	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HGNGGLLK_00616	7.91e-125	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_00617	1.65e-110	-	-	-	L	-	-	-	Helix-turn-helix domain
HGNGGLLK_00618	2.77e-64	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HGNGGLLK_00619	1.32e-247	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HGNGGLLK_00620	2.83e-159	cas4	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	Domain of unknown function DUF83
HGNGGLLK_00621	2.95e-207	csd2	-	-	L	ko:K19115,ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
HGNGGLLK_00622	0.0	csd1	-	-	M	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
HGNGGLLK_00623	1.99e-182	cas5	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
HGNGGLLK_00624	0.0	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HGNGGLLK_00625	4.77e-110	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HGNGGLLK_00626	6.59e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HGNGGLLK_00627	3.26e-194	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HGNGGLLK_00628	8.23e-92	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HGNGGLLK_00629	1.29e-181	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HGNGGLLK_00630	1.52e-114	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HGNGGLLK_00631	9.17e-54	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HGNGGLLK_00632	4.94e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HGNGGLLK_00633	7.96e-158	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HGNGGLLK_00634	1.28e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGNGGLLK_00635	1.74e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HGNGGLLK_00636	4.79e-196	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HGNGGLLK_00637	5.7e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HGNGGLLK_00638	1.24e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
HGNGGLLK_00639	5.46e-71	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
HGNGGLLK_00640	7.45e-196	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_00641	1.18e-291	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00642	9.99e-47	-	-	-	L	-	-	-	Helix-turn-helix domain
HGNGGLLK_00643	6.63e-186	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00644	8.88e-268	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGNGGLLK_00645	8.28e-292	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00648	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HGNGGLLK_00649	1.72e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HGNGGLLK_00650	3.8e-287	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HGNGGLLK_00651	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HGNGGLLK_00652	3.99e-166	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HGNGGLLK_00653	1.65e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGNGGLLK_00654	2.2e-215	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HGNGGLLK_00655	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HGNGGLLK_00656	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HGNGGLLK_00657	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HGNGGLLK_00658	1e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HGNGGLLK_00659	9.12e-161	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HGNGGLLK_00660	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HGNGGLLK_00661	2.53e-210	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HGNGGLLK_00662	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HGNGGLLK_00663	1.68e-169	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HGNGGLLK_00664	5.57e-316	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HGNGGLLK_00665	5.61e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HGNGGLLK_00666	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGNGGLLK_00667	9.67e-274	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HGNGGLLK_00668	1.9e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HGNGGLLK_00669	1.03e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HGNGGLLK_00671	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HGNGGLLK_00672	4.92e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HGNGGLLK_00673	1.14e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HGNGGLLK_00674	1.39e-200	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HGNGGLLK_00675	1.64e-25	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGNGGLLK_00676	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGNGGLLK_00677	2e-206	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HGNGGLLK_00678	1.98e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HGNGGLLK_00679	2.1e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HGNGGLLK_00680	4.18e-263	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HGNGGLLK_00681	8.74e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HGNGGLLK_00682	4.89e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HGNGGLLK_00683	1.89e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HGNGGLLK_00684	1.29e-148	-	-	-	K	-	-	-	Transcriptional regulator
HGNGGLLK_00686	3.15e-120	-	-	-	S	-	-	-	Protein conserved in bacteria
HGNGGLLK_00687	2.34e-226	-	-	-	-	-	-	-	-
HGNGGLLK_00688	5.44e-201	-	-	-	-	-	-	-	-
HGNGGLLK_00689	4.76e-19	-	-	-	-	-	-	-	-
HGNGGLLK_00690	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HGNGGLLK_00691	6.29e-221	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HGNGGLLK_00692	3.51e-33	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HGNGGLLK_00693	5.91e-93	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HGNGGLLK_00694	1.83e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HGNGGLLK_00695	1.14e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HGNGGLLK_00696	7.12e-150	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HGNGGLLK_00697	4.45e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HGNGGLLK_00698	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HGNGGLLK_00699	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HGNGGLLK_00700	0.0	-	-	-	S	-	-	-	membrane
HGNGGLLK_00701	1.81e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGNGGLLK_00702	2.93e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HGNGGLLK_00703	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGNGGLLK_00704	4.45e-253	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HGNGGLLK_00705	1.44e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HGNGGLLK_00706	4.08e-117	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HGNGGLLK_00707	4.52e-181	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGNGGLLK_00708	8.13e-62	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HGNGGLLK_00709	5.83e-199	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGNGGLLK_00710	5.31e-90	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HGNGGLLK_00711	1.88e-298	-	-	-	V	-	-	-	MatE
HGNGGLLK_00712	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HGNGGLLK_00713	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HGNGGLLK_00714	7.89e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HGNGGLLK_00715	4.81e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HGNGGLLK_00716	4.11e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HGNGGLLK_00717	7.76e-182	yqeM	-	-	Q	-	-	-	Methyltransferase
HGNGGLLK_00718	1.14e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HGNGGLLK_00719	5.53e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HGNGGLLK_00720	6.58e-120	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HGNGGLLK_00721	1.38e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HGNGGLLK_00722	2.29e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HGNGGLLK_00723	1.69e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HGNGGLLK_00724	6.02e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HGNGGLLK_00725	2.58e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HGNGGLLK_00726	6.64e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HGNGGLLK_00727	5.22e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HGNGGLLK_00728	6.95e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HGNGGLLK_00729	3.11e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HGNGGLLK_00730	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HGNGGLLK_00731	3.44e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HGNGGLLK_00732	4.15e-137	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HGNGGLLK_00733	7.57e-208	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HGNGGLLK_00734	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGNGGLLK_00735	1.14e-178	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HGNGGLLK_00736	1.24e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HGNGGLLK_00737	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HGNGGLLK_00738	9.14e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGNGGLLK_00739	1.53e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
HGNGGLLK_00740	6.83e-76	-	-	-	S	-	-	-	Small secreted protein
HGNGGLLK_00741	9.51e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HGNGGLLK_00742	5.42e-275	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HGNGGLLK_00743	3.68e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_00744	4.29e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HGNGGLLK_00746	6.67e-192	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HGNGGLLK_00747	2.59e-230	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HGNGGLLK_00748	3.95e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HGNGGLLK_00749	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HGNGGLLK_00750	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HGNGGLLK_00752	4.86e-53	-	-	-	-	-	-	-	-
HGNGGLLK_00754	1.54e-259	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HGNGGLLK_00755	1.12e-136	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HGNGGLLK_00756	7.08e-310	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HGNGGLLK_00757	1.13e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HGNGGLLK_00758	7.52e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HGNGGLLK_00759	9.96e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HGNGGLLK_00760	2.89e-152	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HGNGGLLK_00761	3.04e-233	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HGNGGLLK_00762	4.91e-143	-	-	-	-	-	-	-	-
HGNGGLLK_00763	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HGNGGLLK_00764	1.39e-241	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGNGGLLK_00765	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HGNGGLLK_00766	2.01e-113	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HGNGGLLK_00767	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HGNGGLLK_00768	2.29e-196	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HGNGGLLK_00769	2.84e-82	-	-	-	S	-	-	-	Domain of unknown function DUF302
HGNGGLLK_00770	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HGNGGLLK_00771	8.13e-56	-	-	-	-	-	-	-	-
HGNGGLLK_00772	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HGNGGLLK_00773	1.02e-163	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HGNGGLLK_00774	2.08e-284	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HGNGGLLK_00775	6.54e-181	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGNGGLLK_00776	3.78e-271	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HGNGGLLK_00777	3.23e-64	-	-	-	-	-	-	-	-
HGNGGLLK_00778	2.7e-126	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HGNGGLLK_00779	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HGNGGLLK_00780	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HGNGGLLK_00781	1.83e-313	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HGNGGLLK_00782	3.91e-31	-	-	-	-	-	-	-	-
HGNGGLLK_00785	6.7e-303	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_00786	1.21e-104	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_00788	1.03e-146	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HGNGGLLK_00789	6.84e-103	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HGNGGLLK_00790	3.6e-112	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HGNGGLLK_00791	1.22e-92	-	-	-	M	-	-	-	LysM domain protein
HGNGGLLK_00792	6.79e-253	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HGNGGLLK_00793	1.85e-301	-	-	-	F	ko:K03458	-	ko00000	Permease
HGNGGLLK_00794	5.96e-206	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
HGNGGLLK_00795	2.99e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HGNGGLLK_00796	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HGNGGLLK_00797	1.11e-145	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HGNGGLLK_00798	3.37e-183	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HGNGGLLK_00799	9.58e-19	ebrB	-	-	U	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HGNGGLLK_00800	3.13e-06	-	-	-	K	-	-	-	Transcriptional regulator
HGNGGLLK_00811	8.34e-101	-	-	-	-	-	-	-	-
HGNGGLLK_00814	2.81e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HGNGGLLK_00815	4.63e-230	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGNGGLLK_00816	1.28e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HGNGGLLK_00817	5.62e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HGNGGLLK_00818	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGNGGLLK_00819	4.32e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HGNGGLLK_00820	5.36e-07	-	-	-	-	-	-	-	-
HGNGGLLK_00821	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HGNGGLLK_00822	5.03e-166	-	-	-	F	-	-	-	NUDIX domain
HGNGGLLK_00823	1.22e-142	pncA	-	-	Q	-	-	-	Isochorismatase family
HGNGGLLK_00824	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGNGGLLK_00825	8.07e-126	-	-	-	S	-	-	-	Pfam:DUF3816
HGNGGLLK_00826	9.48e-182	-	-	-	G	-	-	-	MucBP domain
HGNGGLLK_00827	2.79e-176	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGNGGLLK_00828	1.81e-207	-	-	-	EG	-	-	-	EamA-like transporter family
HGNGGLLK_00829	6.84e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HGNGGLLK_00830	3.32e-303	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_00831	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_00833	2.32e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_00834	8.46e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HGNGGLLK_00835	1.6e-220	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGNGGLLK_00836	3.77e-102	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HGNGGLLK_00837	2.15e-266	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HGNGGLLK_00838	1.16e-188	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HGNGGLLK_00839	3.67e-127	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HGNGGLLK_00840	2.62e-119	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HGNGGLLK_00841	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HGNGGLLK_00842	5.22e-211	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HGNGGLLK_00843	3.06e-218	yueF	-	-	S	-	-	-	AI-2E family transporter
HGNGGLLK_00844	9.36e-204	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HGNGGLLK_00845	8.03e-10	-	-	-	-	-	-	-	-
HGNGGLLK_00846	2.2e-119	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
HGNGGLLK_00847	7.29e-71	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGNGGLLK_00850	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HGNGGLLK_00851	2.67e-278	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_00852	1.54e-253	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HGNGGLLK_00853	5.66e-280	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HGNGGLLK_00854	1.12e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_00855	1.21e-62	cps3I	-	-	G	-	-	-	Acyltransferase family
HGNGGLLK_00856	2.68e-39	-	-	-	M	-	-	-	biosynthesis protein
HGNGGLLK_00857	1.35e-116	cps3F	-	-	-	-	-	-	-
HGNGGLLK_00858	1.71e-191	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HGNGGLLK_00859	3.48e-152	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HGNGGLLK_00860	1.18e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HGNGGLLK_00862	4.37e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HGNGGLLK_00863	1.01e-192	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HGNGGLLK_00864	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
HGNGGLLK_00865	1.17e-214	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HGNGGLLK_00866	1.66e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HGNGGLLK_00867	7.97e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HGNGGLLK_00869	2.25e-302	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HGNGGLLK_00870	2.35e-242	mocA	-	-	S	-	-	-	Oxidoreductase
HGNGGLLK_00871	5.17e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HGNGGLLK_00872	1.8e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HGNGGLLK_00873	3.98e-202	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HGNGGLLK_00874	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HGNGGLLK_00875	2.58e-180	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HGNGGLLK_00876	2.89e-44	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HGNGGLLK_00878	2.77e-290	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00879	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HGNGGLLK_00880	5.91e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HGNGGLLK_00881	8.96e-136	-	-	-	-	-	-	-	-
HGNGGLLK_00882	6.85e-277	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HGNGGLLK_00883	2.39e-131	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HGNGGLLK_00884	9.79e-62	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HGNGGLLK_00885	3.99e-100	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HGNGGLLK_00886	6.2e-129	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HGNGGLLK_00887	9.54e-134	-	-	-	S	-	-	-	CAAX protease self-immunity
HGNGGLLK_00889	3.51e-154	-	-	-	Q	-	-	-	Methyltransferase domain
HGNGGLLK_00890	8.6e-88	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HGNGGLLK_00891	5.23e-67	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
HGNGGLLK_00892	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HGNGGLLK_00893	5.51e-116	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HGNGGLLK_00894	7.61e-95	-	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	Amidinotransferase
HGNGGLLK_00896	4.35e-247	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HGNGGLLK_00898	2.59e-235	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HGNGGLLK_00899	4.3e-30	-	-	-	D	ko:K19158	-	ko00000,ko01000,ko02048	mRNA cleavage
HGNGGLLK_00900	7.53e-18	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HGNGGLLK_00901	7.69e-36	-	-	-	L	-	-	-	Helix-turn-helix domain
HGNGGLLK_00902	2.14e-195	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_00903	1.35e-164	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_00904	2.21e-160	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_00905	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HGNGGLLK_00906	5.56e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_00907	5.9e-51	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_00908	8.28e-292	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_00909	3.68e-178	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_00910	8.54e-63	-	-	-	L	-	-	-	Helix-turn-helix domain
HGNGGLLK_00911	1.56e-114	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_00912	9.02e-146	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HGNGGLLK_00913	1.19e-61	-	-	-	D	-	-	-	Di-iron-containing protein involved in the repair of iron-sulfur clusters
HGNGGLLK_00914	1.04e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HGNGGLLK_00915	0.0	-	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HGNGGLLK_00916	3.3e-105	-	-	-	-	-	-	-	-
HGNGGLLK_00917	1.73e-218	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HGNGGLLK_00918	3.46e-67	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HGNGGLLK_00920	7.83e-65	-	-	-	K	-	-	-	TRANSCRIPTIONal
HGNGGLLK_00921	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGNGGLLK_00922	3.07e-238	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HGNGGLLK_00923	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGNGGLLK_00924	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HGNGGLLK_00925	6.72e-63	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGNGGLLK_00926	2.4e-227	camS	-	-	S	-	-	-	sex pheromone
HGNGGLLK_00927	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HGNGGLLK_00928	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HGNGGLLK_00929	7.47e-280	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HGNGGLLK_00930	9.56e-133	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HGNGGLLK_00931	2.33e-142	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HGNGGLLK_00932	1.74e-177	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HGNGGLLK_00933	1.35e-164	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_00934	5.14e-97	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_00935	4.2e-241	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HGNGGLLK_00936	2.14e-60	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_00937	5.03e-239	-	-	-	S	-	-	-	interspecies interaction between organisms
HGNGGLLK_00938	2.78e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HGNGGLLK_00939	5.57e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HGNGGLLK_00940	1.09e-184	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HGNGGLLK_00941	2.37e-178	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGNGGLLK_00942	2.06e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGNGGLLK_00943	6.12e-193	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGNGGLLK_00944	1.02e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HGNGGLLK_00945	3.48e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGNGGLLK_00946	8.02e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HGNGGLLK_00947	1.32e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HGNGGLLK_00948	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HGNGGLLK_00949	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HGNGGLLK_00950	2.16e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HGNGGLLK_00951	5.51e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HGNGGLLK_00952	3.5e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HGNGGLLK_00953	6.96e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HGNGGLLK_00954	3.59e-113	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HGNGGLLK_00955	5.55e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HGNGGLLK_00956	2.4e-120	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HGNGGLLK_00957	6.28e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HGNGGLLK_00958	2.46e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGNGGLLK_00959	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HGNGGLLK_00960	1.28e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HGNGGLLK_00961	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HGNGGLLK_00962	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HGNGGLLK_00963	1.35e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HGNGGLLK_00964	2.78e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HGNGGLLK_00965	3.43e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HGNGGLLK_00966	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HGNGGLLK_00967	1.51e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HGNGGLLK_00968	3.32e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HGNGGLLK_00969	2.76e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HGNGGLLK_00970	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HGNGGLLK_00971	5.89e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HGNGGLLK_00972	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HGNGGLLK_00973	1.35e-164	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_00974	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HGNGGLLK_00975	4.15e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HGNGGLLK_00976	3.58e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HGNGGLLK_00977	1.77e-40	pilD	3.4.23.43	-	NOU	ko:K02236,ko:K02506,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	aspartic-type endopeptidase activity
HGNGGLLK_00978	3.02e-275	-	-	-	-	-	-	-	-
HGNGGLLK_00979	2.92e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HGNGGLLK_00980	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGNGGLLK_00981	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGNGGLLK_00982	1.16e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HGNGGLLK_00983	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HGNGGLLK_00984	6.36e-103	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HGNGGLLK_00985	2.27e-246	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HGNGGLLK_00986	5.89e-171	XK27_07210	-	-	S	-	-	-	B3 4 domain
HGNGGLLK_00987	1.23e-153	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
HGNGGLLK_00989	2.76e-68	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HGNGGLLK_00990	7.14e-191	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HGNGGLLK_00991	4.09e-57	-	-	-	IQ	-	-	-	reductase
HGNGGLLK_00992	2.74e-14	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGNGGLLK_00993	8.64e-312	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGNGGLLK_00999	2.71e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HGNGGLLK_01000	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HGNGGLLK_01002	2.43e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HGNGGLLK_01003	3.13e-149	-	-	-	I	-	-	-	phosphatase
HGNGGLLK_01004	8.17e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HGNGGLLK_01005	7.83e-161	-	-	-	S	-	-	-	Putative threonine/serine exporter
HGNGGLLK_01006	5.79e-39	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HGNGGLLK_01007	2.24e-157	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HGNGGLLK_01008	3.58e-208	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HGNGGLLK_01009	9.24e-151	-	-	-	S	-	-	-	membrane
HGNGGLLK_01010	3.32e-142	-	-	-	S	-	-	-	VIT family
HGNGGLLK_01011	2.49e-110	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HGNGGLLK_01012	1.18e-28	elaA	-	-	S	ko:K02348	-	ko00000	acyltransferase COG2153
HGNGGLLK_01013	2.28e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HGNGGLLK_01014	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGNGGLLK_01015	1.15e-77	-	-	-	-	-	-	-	-
HGNGGLLK_01016	3.98e-96	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HGNGGLLK_01017	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HGNGGLLK_01018	2.34e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HGNGGLLK_01019	2.02e-186	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HGNGGLLK_01020	1.04e-217	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HGNGGLLK_01022	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGNGGLLK_01023	7.04e-139	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HGNGGLLK_01024	1.92e-241	-	-	-	I	-	-	-	Alpha beta
HGNGGLLK_01025	4.18e-156	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HGNGGLLK_01026	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HGNGGLLK_01027	2.63e-208	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HGNGGLLK_01028	5.02e-288	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HGNGGLLK_01029	2.25e-270	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HGNGGLLK_01030	6.54e-283	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HGNGGLLK_01031	2.48e-117	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HGNGGLLK_01032	2.02e-233	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HGNGGLLK_01033	8.85e-289	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HGNGGLLK_01034	1.12e-98	mleR	-	-	K	-	-	-	LysR family
HGNGGLLK_01035	3.11e-73	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HGNGGLLK_01036	8.89e-96	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_01037	7.63e-137	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_01038	8.95e-161	-	-	-	S	-	-	-	EcsC protein family
HGNGGLLK_01039	1.31e-35	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HGNGGLLK_01041	5.42e-226	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HGNGGLLK_01043	7.96e-30	-	-	-	L	-	-	-	Helix-turn-helix domain
HGNGGLLK_01044	3.76e-155	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_01045	1.87e-139	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGNGGLLK_01046	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HGNGGLLK_01047	3.35e-249	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
HGNGGLLK_01048	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HGNGGLLK_01049	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HGNGGLLK_01050	1.71e-211	-	-	-	K	-	-	-	LysR substrate binding domain
HGNGGLLK_01051	2.72e-212	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HGNGGLLK_01052	5.32e-142	-	-	-	-	-	-	-	-
HGNGGLLK_01054	0.0	potE	-	-	E	-	-	-	Amino Acid
HGNGGLLK_01055	3.77e-217	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HGNGGLLK_01056	1.47e-286	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HGNGGLLK_01057	7.4e-126	-	-	-	-	-	-	-	-
HGNGGLLK_01058	4.28e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HGNGGLLK_01059	3.77e-139	-	-	-	I	-	-	-	PAP2 superfamily
HGNGGLLK_01060	5.37e-72	-	-	-	S	-	-	-	MazG-like family
HGNGGLLK_01061	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HGNGGLLK_01062	2.72e-93	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HGNGGLLK_01063	3.26e-124	-	-	-	K	-	-	-	transcriptional regulator
HGNGGLLK_01064	4.67e-170	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HGNGGLLK_01067	8.11e-52	-	-	-	S	-	-	-	Cytochrome B5
HGNGGLLK_01068	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HGNGGLLK_01069	2.47e-273	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HGNGGLLK_01070	5.49e-22	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HGNGGLLK_01071	5.59e-250	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HGNGGLLK_01072	1.29e-133	-	-	-	NU	-	-	-	mannosyl-glycoprotein
HGNGGLLK_01073	1.03e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HGNGGLLK_01074	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HGNGGLLK_01075	5.09e-107	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HGNGGLLK_01076	1.9e-94	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HGNGGLLK_01077	2.19e-172	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HGNGGLLK_01078	3.48e-245	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HGNGGLLK_01079	2.33e-89	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HGNGGLLK_01080	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HGNGGLLK_01081	1.41e-163	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
HGNGGLLK_01082	3.13e-274	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
HGNGGLLK_01083	4.9e-264	-	-	-	EGP	-	-	-	Major Facilitator
HGNGGLLK_01084	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HGNGGLLK_01085	5.57e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HGNGGLLK_01086	2.35e-196	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HGNGGLLK_01088	2.34e-286	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_01089	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGNGGLLK_01090	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HGNGGLLK_01091	2.13e-75	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HGNGGLLK_01092	3.59e-10	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HGNGGLLK_01093	2.16e-201	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HGNGGLLK_01094	2.74e-68	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HGNGGLLK_01095	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HGNGGLLK_01096	2.01e-295	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HGNGGLLK_01097	8.4e-302	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGNGGLLK_01098	3.41e-84	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_01099	3.77e-219	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_01100	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGNGGLLK_01101	4.59e-133	-	-	-	K	-	-	-	Transcriptional regulator
HGNGGLLK_01102	6.15e-31	XK27_06785	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HGNGGLLK_01103	7e-218	-	-	-	M	ko:K02004	-	ko00000,ko00002,ko02000	Membrane
HGNGGLLK_01104	3.17e-74	-	-	-	S	-	-	-	FMN_bind
HGNGGLLK_01105	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_01106	8.31e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HGNGGLLK_01107	2.89e-88	-	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HGNGGLLK_01108	2.52e-66	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HGNGGLLK_01109	9.58e-65	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
HGNGGLLK_01110	6.28e-221	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HGNGGLLK_01111	6.7e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
HGNGGLLK_01112	2.77e-134	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HGNGGLLK_01113	1.87e-156	-	-	-	-	-	-	-	-
HGNGGLLK_01115	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HGNGGLLK_01116	0.0	-	1.7.2.5	-	P	ko:K04561	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Cytochrome C and Quinol oxidase polypeptide I
HGNGGLLK_01117	2.86e-70	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_01118	1.33e-34	-	-	-	-	-	-	-	-
HGNGGLLK_01119	2.05e-174	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HGNGGLLK_01120	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HGNGGLLK_01121	0.0	-	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	Putative ATP-dependent Lon protease
HGNGGLLK_01122	0.0	-	-	-	S	-	-	-	PglZ domain
HGNGGLLK_01123	1.54e-241	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HGNGGLLK_01124	7.69e-246	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HGNGGLLK_01125	0.0	-	-	-	V	-	-	-	Eco57I restriction-modification methylase
HGNGGLLK_01126	0.0	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HGNGGLLK_01127	1.86e-129	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
HGNGGLLK_01128	5.79e-70	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
HGNGGLLK_01129	1.35e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
HGNGGLLK_01130	6.78e-291	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HGNGGLLK_01131	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HGNGGLLK_01132	1.93e-145	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HGNGGLLK_01133	6.69e-101	dltr	-	-	K	-	-	-	response regulator
HGNGGLLK_01134	5.13e-165	sptS	-	-	T	-	-	-	Histidine kinase
HGNGGLLK_01135	1.61e-223	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HGNGGLLK_01136	4.65e-134	-	-	-	K	-	-	-	acetyltransferase
HGNGGLLK_01137	3.52e-173	-	-	-	IQ	-	-	-	dehydrogenase reductase
HGNGGLLK_01138	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HGNGGLLK_01139	9.54e-205	-	-	-	EG	-	-	-	EamA-like transporter family
HGNGGLLK_01140	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HGNGGLLK_01141	2.5e-153	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HGNGGLLK_01142	1.92e-155	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HGNGGLLK_01143	8.03e-295	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HGNGGLLK_01144	3.6e-265	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HGNGGLLK_01145	3.55e-173	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HGNGGLLK_01146	0.0	-	-	-	E	-	-	-	amino acid
HGNGGLLK_01147	7.07e-134	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGNGGLLK_01148	5.8e-178	-	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
HGNGGLLK_01150	3.11e-310	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HGNGGLLK_01151	4.23e-122	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HGNGGLLK_01152	1.38e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HGNGGLLK_01153	1.66e-215	-	-	-	-	-	-	-	-
HGNGGLLK_01154	2.5e-09	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HGNGGLLK_01155	2.97e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HGNGGLLK_01156	9.61e-137	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HGNGGLLK_01157	8.97e-95	-	-	-	F	-	-	-	Nudix hydrolase
HGNGGLLK_01158	2.84e-261	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HGNGGLLK_01159	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HGNGGLLK_01160	2.73e-227	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HGNGGLLK_01161	5.93e-149	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HGNGGLLK_01162	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HGNGGLLK_01163	8.41e-235	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HGNGGLLK_01164	1.08e-216	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HGNGGLLK_01165	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGNGGLLK_01166	1.64e-108	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HGNGGLLK_01167	8.3e-141	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HGNGGLLK_01168	1.64e-262	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HGNGGLLK_01169	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HGNGGLLK_01170	8.03e-231	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HGNGGLLK_01171	3.76e-193	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HGNGGLLK_01172	1.32e-170	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_01174	2.17e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HGNGGLLK_01175	1.51e-297	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HGNGGLLK_01176	7.93e-217	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HGNGGLLK_01177	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HGNGGLLK_01178	2.41e-235	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HGNGGLLK_01179	9.89e-207	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HGNGGLLK_01180	1.72e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGNGGLLK_01181	3.45e-74	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HGNGGLLK_01182	5.82e-182	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HGNGGLLK_01183	1.12e-212	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HGNGGLLK_01184	3.77e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HGNGGLLK_01185	1.24e-298	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HGNGGLLK_01186	1.13e-191	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HGNGGLLK_01187	3.31e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HGNGGLLK_01188	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HGNGGLLK_01189	1.3e-110	-	-	-	-	-	-	-	-
HGNGGLLK_01190	3.13e-141	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
HGNGGLLK_01191	8.02e-130	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HGNGGLLK_01192	6.69e-47	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HGNGGLLK_01193	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HGNGGLLK_01194	1.51e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HGNGGLLK_01195	3.41e-231	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HGNGGLLK_01196	4.09e-131	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HGNGGLLK_01197	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_01198	8.69e-149	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HGNGGLLK_01199	2.52e-22	-	-	-	-	-	-	-	-
HGNGGLLK_01200	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HGNGGLLK_01201	2.27e-245	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HGNGGLLK_01202	9.46e-96	-	-	-	O	-	-	-	OsmC-like protein
HGNGGLLK_01203	1.46e-237	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HGNGGLLK_01204	2.22e-98	-	-	-	K	-	-	-	Transcriptional regulator
HGNGGLLK_01205	1.92e-203	-	-	-	-	-	-	-	-
HGNGGLLK_01206	4.83e-10	-	-	-	-	-	-	-	-
HGNGGLLK_01207	6.25e-78	-	-	-	-	-	-	-	-
HGNGGLLK_01208	2.16e-98	uspA3	-	-	T	-	-	-	universal stress protein
HGNGGLLK_01210	6.96e-175	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HGNGGLLK_01211	2.72e-314	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
HGNGGLLK_01212	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HGNGGLLK_01213	6.86e-175	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
HGNGGLLK_01214	3.16e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HGNGGLLK_01215	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HGNGGLLK_01216	3.19e-244	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HGNGGLLK_01217	2.65e-54	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HGNGGLLK_01218	9.39e-57	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGNGGLLK_01219	8.7e-162	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HGNGGLLK_01220	6.27e-109	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_01221	2.18e-162	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_01222	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGNGGLLK_01223	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HGNGGLLK_01224	8.61e-89	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HGNGGLLK_01225	1.59e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGNGGLLK_01226	1.85e-214	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HGNGGLLK_01227	9.74e-146	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HGNGGLLK_01228	1.23e-254	-	-	-	S	-	-	-	Domain of unknown function (DUF4432)
HGNGGLLK_01229	2.57e-224	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGNGGLLK_01230	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HGNGGLLK_01231	4.05e-242	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HGNGGLLK_01232	0.0	potE	-	-	E	-	-	-	Amino Acid
HGNGGLLK_01234	3.37e-291	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_01236	2.4e-60	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_01237	2.08e-93	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HGNGGLLK_01238	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HGNGGLLK_01239	1.83e-22	-	-	-	-	-	-	-	-
HGNGGLLK_01240	4.76e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HGNGGLLK_01241	9.09e-26	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
HGNGGLLK_01242	1.83e-158	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HGNGGLLK_01243	1.71e-122	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HGNGGLLK_01244	8.28e-292	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_01245	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HGNGGLLK_01246	2.4e-188	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HGNGGLLK_01247	3.81e-169	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HGNGGLLK_01248	4.23e-115	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HGNGGLLK_01249	3.78e-167	-	-	-	-	-	-	-	-
HGNGGLLK_01250	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HGNGGLLK_01251	8.78e-198	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HGNGGLLK_01252	9.84e-112	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HGNGGLLK_01253	1.14e-114	-	-	-	GM	-	-	-	epimerase
HGNGGLLK_01254	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HGNGGLLK_01255	3.05e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HGNGGLLK_01256	1.81e-98	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
HGNGGLLK_01257	3.6e-266	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HGNGGLLK_01258	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HGNGGLLK_01259	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGNGGLLK_01260	3.03e-106	usp5	-	-	T	-	-	-	universal stress protein
HGNGGLLK_01261	4.36e-103	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HGNGGLLK_01262	2.31e-181	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGNGGLLK_01263	4.82e-229	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HGNGGLLK_01264	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HGNGGLLK_01265	1.29e-298	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGNGGLLK_01266	2.51e-160	-	-	-	S	-	-	-	Membrane
HGNGGLLK_01267	1.92e-51	-	-	-	L	ko:K07483	-	ko00000	Transposase
HGNGGLLK_01268	4.33e-186	-	-	-	L	-	-	-	4.5 Transposon and IS
HGNGGLLK_01269	0.0	dld	1.1.5.12	-	C	ko:K03777	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-lactate dehydrogenase, membrane binding
HGNGGLLK_01270	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HGNGGLLK_01273	3.53e-28	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_01274	5.92e-157	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HGNGGLLK_01276	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HGNGGLLK_01279	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HGNGGLLK_01280	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HGNGGLLK_01281	3.03e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HGNGGLLK_01282	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HGNGGLLK_01283	2.97e-284	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HGNGGLLK_01284	7.74e-231	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HGNGGLLK_01285	5.85e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HGNGGLLK_01286	2.44e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HGNGGLLK_01287	1.21e-48	-	-	-	-	-	-	-	-
HGNGGLLK_01288	2.05e-174	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_01289	3.51e-154	-	-	-	U	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HGNGGLLK_01290	4.43e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HGNGGLLK_01291	3.7e-70	-	-	-	-	-	-	-	-
HGNGGLLK_01292	3.47e-216	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGNGGLLK_01293	2.57e-104	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGNGGLLK_01294	1.77e-187	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HGNGGLLK_01295	2.01e-119	ymdB	-	-	S	-	-	-	Macro domain protein
HGNGGLLK_01296	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HGNGGLLK_01297	3e-291	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HGNGGLLK_01298	8.5e-61	-	-	-	-	-	-	-	-
HGNGGLLK_01299	4.33e-271	-	-	-	S	-	-	-	Putative metallopeptidase domain
HGNGGLLK_01300	5.72e-263	-	-	-	S	-	-	-	associated with various cellular activities
HGNGGLLK_01301	2e-150	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HGNGGLLK_01302	2.45e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HGNGGLLK_01304	2.32e-161	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HGNGGLLK_01305	8.76e-73	-	-	-	-	-	-	-	-
HGNGGLLK_01306	3.04e-140	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HGNGGLLK_01307	6.55e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HGNGGLLK_01308	2.68e-135	-	-	-	-	-	-	-	-
HGNGGLLK_01309	1.11e-35	-	-	-	-	-	-	-	-
HGNGGLLK_01310	1e-216	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HGNGGLLK_01311	1.54e-313	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGNGGLLK_01312	3.55e-61	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HGNGGLLK_01313	3.97e-298	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_01314	3.88e-106	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_01315	7.5e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HGNGGLLK_01316	2.9e-158	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_01317	1.65e-208	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HGNGGLLK_01318	3.89e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HGNGGLLK_01319	5.52e-241	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HGNGGLLK_01320	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HGNGGLLK_01321	1.71e-52	-	-	-	-	-	-	-	-
HGNGGLLK_01322	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGNGGLLK_01323	3.36e-110	-	-	-	L	-	-	-	nuclease
HGNGGLLK_01324	7.26e-208	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HGNGGLLK_01325	4.92e-305	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_01326	2.38e-73	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_01327	3.8e-31	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HGNGGLLK_01328	3.1e-215	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HGNGGLLK_01329	6.72e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HGNGGLLK_01330	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGNGGLLK_01331	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGNGGLLK_01332	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HGNGGLLK_01333	1.02e-282	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HGNGGLLK_01334	1.77e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HGNGGLLK_01335	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_01336	1.87e-57	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_01337	7.83e-155	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_01338	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HGNGGLLK_01339	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HGNGGLLK_01340	1.02e-187	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HGNGGLLK_01341	4.99e-187	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGNGGLLK_01342	4.38e-74	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HGNGGLLK_01343	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HGNGGLLK_01345	9.49e-317	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HGNGGLLK_01346	5.29e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HGNGGLLK_01347	1.45e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HGNGGLLK_01348	2.5e-258	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HGNGGLLK_01349	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGNGGLLK_01350	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGNGGLLK_01351	6.02e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HGNGGLLK_01352	1.88e-164	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HGNGGLLK_01353	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HGNGGLLK_01354	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HGNGGLLK_01355	2.63e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HGNGGLLK_01356	4.28e-309	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HGNGGLLK_01357	1.79e-267	-	-	-	E	-	-	-	Major Facilitator Superfamily
HGNGGLLK_01358	8.32e-66	-	-	-	-	-	-	-	-
HGNGGLLK_01359	2.08e-241	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HGNGGLLK_01362	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HGNGGLLK_01363	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HGNGGLLK_01364	1.27e-306	yycH	-	-	S	-	-	-	YycH protein
HGNGGLLK_01365	2.05e-185	yycI	-	-	S	-	-	-	YycH protein
HGNGGLLK_01366	5.49e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HGNGGLLK_01367	9.52e-270	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HGNGGLLK_01368	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HGNGGLLK_01369	3.03e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
HGNGGLLK_01370	6.58e-225	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HGNGGLLK_01371	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HGNGGLLK_01372	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HGNGGLLK_01373	7.69e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HGNGGLLK_01374	2.01e-140	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
HGNGGLLK_01375	1.04e-244	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HGNGGLLK_01376	6.65e-234	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HGNGGLLK_01377	1.97e-231	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGNGGLLK_01378	5.91e-279	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HGNGGLLK_01379	4.71e-47	-	-	-	-	-	-	-	-
HGNGGLLK_01380	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HGNGGLLK_01381	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGNGGLLK_01382	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HGNGGLLK_01383	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HGNGGLLK_01384	3.09e-211	-	-	-	C	-	-	-	Aldo keto reductase
HGNGGLLK_01385	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HGNGGLLK_01386	3.67e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HGNGGLLK_01387	1.51e-242	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HGNGGLLK_01388	4.61e-166	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HGNGGLLK_01389	1.77e-119	-	-	-	K	-	-	-	transcriptional regulator
HGNGGLLK_01390	8.06e-212	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGNGGLLK_01391	9.69e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HGNGGLLK_01392	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HGNGGLLK_01393	8.04e-124	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HGNGGLLK_01394	9.7e-168	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HGNGGLLK_01395	6.19e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HGNGGLLK_01396	1.98e-21	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HGNGGLLK_01397	3.97e-62	-	-	-	-	-	-	-	-
HGNGGLLK_01398	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HGNGGLLK_01399	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HGNGGLLK_01400	1.34e-197	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HGNGGLLK_01401	2.24e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGNGGLLK_01402	3.68e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HGNGGLLK_01403	1.82e-276	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HGNGGLLK_01404	1.14e-311	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGNGGLLK_01405	1.83e-106	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HGNGGLLK_01406	1.13e-308	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HGNGGLLK_01407	5.37e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGNGGLLK_01408	7.85e-307	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HGNGGLLK_01409	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGNGGLLK_01410	9.8e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HGNGGLLK_01411	1.71e-104	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_01412	3.32e-303	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_01413	6.82e-274	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HGNGGLLK_01414	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HGNGGLLK_01415	5.02e-313	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HGNGGLLK_01417	1.79e-19	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGNGGLLK_01418	9.63e-253	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGNGGLLK_01419	1.15e-238	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HGNGGLLK_01421	1.62e-287	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HGNGGLLK_01422	4.66e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_01423	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HGNGGLLK_01424	4.04e-304	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_01425	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_01426	5.13e-244	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HGNGGLLK_01427	3.75e-287	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HGNGGLLK_01428	1.27e-271	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
HGNGGLLK_01429	1.89e-184	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HGNGGLLK_01430	5.01e-171	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HGNGGLLK_01431	2.48e-204	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HGNGGLLK_01432	5.29e-189	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HGNGGLLK_01433	1.78e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HGNGGLLK_01434	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HGNGGLLK_01435	1.13e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HGNGGLLK_01436	1.71e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGNGGLLK_01437	8.54e-223	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HGNGGLLK_01438	2.36e-170	epsB	-	-	M	-	-	-	biosynthesis protein
HGNGGLLK_01439	6.68e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HGNGGLLK_01440	5.79e-171	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HGNGGLLK_01441	1.45e-86	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HGNGGLLK_01442	5.89e-206	wchF	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
HGNGGLLK_01443	8.19e-147	-	-	-	G	-	-	-	Glycosyltransferase Family 4
HGNGGLLK_01444	3.48e-81	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HGNGGLLK_01446	6.69e-163	-	-	-	M	-	-	-	Stealth protein CR3, conserved region 3
HGNGGLLK_01447	4.87e-129	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HGNGGLLK_01448	2.33e-71	-	2.7.8.12	GT2	V	ko:K09809,ko:K19354	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase, family 2
HGNGGLLK_01449	2.28e-79	-	-	-	-	-	-	-	-
HGNGGLLK_01450	8.48e-55	-	-	-	-	-	-	-	-
HGNGGLLK_01451	1.59e-162	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HGNGGLLK_01452	4.37e-100	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGNGGLLK_01453	2.1e-139	-	-	-	L	-	-	-	4.5 Transposon and IS
HGNGGLLK_01454	3.88e-206	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HGNGGLLK_01455	2.77e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HGNGGLLK_01456	1.39e-258	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGNGGLLK_01457	1.3e-202	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HGNGGLLK_01458	9.46e-38	-	-	-	M	-	-	-	Glycosyltransferase family 92
HGNGGLLK_01460	1.12e-120	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
HGNGGLLK_01461	1.24e-157	vanR	-	-	K	-	-	-	response regulator
HGNGGLLK_01462	1.87e-268	hpk31	-	-	T	-	-	-	Histidine kinase
HGNGGLLK_01463	1.13e-267	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HGNGGLLK_01464	6.18e-180	-	-	-	E	-	-	-	AzlC protein
HGNGGLLK_01465	3.16e-78	-	-	-	S	-	-	-	branched-chain amino acid
HGNGGLLK_01468	2.32e-281	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HGNGGLLK_01469	8.28e-292	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_01470	5.16e-70	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HGNGGLLK_01471	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_01472	4.04e-304	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_01473	1.44e-291	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HGNGGLLK_01474	2.92e-05	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HGNGGLLK_01475	1.16e-222	ydbI	-	-	K	-	-	-	AI-2E family transporter
HGNGGLLK_01476	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HGNGGLLK_01477	3.36e-105	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HGNGGLLK_01478	1.44e-276	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HGNGGLLK_01479	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HGNGGLLK_01480	1.55e-218	hrpQ	4.6.1.1	-	T	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	histone H2A K63-linked ubiquitination
HGNGGLLK_01481	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HGNGGLLK_01482	2.55e-20	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
HGNGGLLK_01483	3.55e-173	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HGNGGLLK_01484	1.36e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGNGGLLK_01485	4.87e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGNGGLLK_01486	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGNGGLLK_01487	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HGNGGLLK_01488	8.9e-247	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HGNGGLLK_01489	1.32e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HGNGGLLK_01490	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HGNGGLLK_01491	1.66e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HGNGGLLK_01492	1.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HGNGGLLK_01493	6.98e-286	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HGNGGLLK_01494	6.78e-225	-	-	-	-	-	-	-	-
HGNGGLLK_01495	8.79e-67	-	-	-	S	-	-	-	Cupredoxin-like domain
HGNGGLLK_01496	3.81e-67	-	-	-	S	-	-	-	Cupredoxin-like domain
HGNGGLLK_01497	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HGNGGLLK_01498	1.69e-35	-	-	-	EGP	-	-	-	Major Facilitator
HGNGGLLK_01499	6.87e-117	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
HGNGGLLK_01500	8.34e-101	-	-	-	-	-	-	-	-
HGNGGLLK_01503	1.35e-164	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_01504	4.43e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HGNGGLLK_01505	1.33e-57	yodA	-	-	S	-	-	-	Tautomerase enzyme
HGNGGLLK_01506	1.84e-155	pnb	-	-	C	-	-	-	nitroreductase
HGNGGLLK_01507	4.34e-126	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
HGNGGLLK_01508	1.27e-101	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HGNGGLLK_01509	1.88e-46	-	-	-	C	-	-	-	Aldo keto reductase
HGNGGLLK_01510	2.02e-31	-	-	-	C	-	-	-	Aldo keto reductase
HGNGGLLK_01511	5.11e-06	-	-	-	S	-	-	-	CsbD-like
HGNGGLLK_01514	1.55e-120	-	-	-	P	-	-	-	Cadmium resistance transporter
HGNGGLLK_01515	1.65e-110	-	-	-	L	-	-	-	Helix-turn-helix domain
HGNGGLLK_01516	7.91e-125	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_01517	1.35e-164	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_01518	1.35e-164	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_01519	2.88e-161	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_01520	1.9e-59	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_01522	2.01e-195	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HGNGGLLK_01523	3.37e-129	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HGNGGLLK_01524	1.03e-129	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HGNGGLLK_01525	8.84e-58	-	-	-	L	-	-	-	Transposase DDE domain group 1
HGNGGLLK_01527	7.32e-86	-	-	-	-	-	-	-	-
HGNGGLLK_01528	8.14e-203	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HGNGGLLK_01529	8.34e-101	-	-	-	-	-	-	-	-
HGNGGLLK_01530	1.14e-231	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGNGGLLK_01531	5.55e-32	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
HGNGGLLK_01532	4.31e-33	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
HGNGGLLK_01533	3.99e-85	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
HGNGGLLK_01534	1.72e-52	-	-	-	C	-	-	-	Protein of unknown function (DUF1116)
HGNGGLLK_01536	0.000192	-	-	-	S	-	-	-	Protein of unknown function (DUF2877)
HGNGGLLK_01537	3.73e-158	cpkA	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Amino acid kinase family
HGNGGLLK_01538	7.41e-227	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HGNGGLLK_01539	2.24e-159	-	-	-	C	-	-	-	nitroreductase
HGNGGLLK_01540	1.98e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HGNGGLLK_01541	1.06e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
HGNGGLLK_01542	1.92e-106	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_01543	4.72e-303	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_01544	2.2e-252	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HGNGGLLK_01545	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HGNGGLLK_01546	3.08e-21	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_01547	7.65e-261	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_01548	2.03e-76	-	-	-	K	-	-	-	Transcriptional regulator
HGNGGLLK_01550	3.03e-181	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HGNGGLLK_01552	9.46e-199	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HGNGGLLK_01553	1.28e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HGNGGLLK_01554	0.0	-	-	-	L	-	-	-	DNA helicase
HGNGGLLK_01555	8.9e-219	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HGNGGLLK_01556	5.79e-288	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HGNGGLLK_01557	1.77e-237	-	-	-	-	-	-	-	-
HGNGGLLK_01558	2.22e-163	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HGNGGLLK_01559	2.38e-272	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HGNGGLLK_01560	2.01e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HGNGGLLK_01561	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGNGGLLK_01562	5.46e-188	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HGNGGLLK_01563	6.51e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HGNGGLLK_01564	6.18e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HGNGGLLK_01565	4.04e-205	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HGNGGLLK_01566	2e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HGNGGLLK_01567	1.98e-123	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HGNGGLLK_01568	3.99e-166	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HGNGGLLK_01569	2.13e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HGNGGLLK_01570	9.91e-302	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HGNGGLLK_01571	7.69e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGNGGLLK_01572	3.55e-76	-	-	-	-	-	-	-	-
HGNGGLLK_01573	1.01e-184	yidA	-	-	S	-	-	-	hydrolase
HGNGGLLK_01574	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HGNGGLLK_01575	2.13e-96	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HGNGGLLK_01576	2.16e-97	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HGNGGLLK_01577	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HGNGGLLK_01578	4.36e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGNGGLLK_01579	3.85e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HGNGGLLK_01580	1.62e-62	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
HGNGGLLK_01581	1.56e-96	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
HGNGGLLK_01582	1.92e-106	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_01583	2.79e-298	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_01584	1.54e-157	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HGNGGLLK_01585	7.41e-61	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGNGGLLK_01586	1.66e-119	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HGNGGLLK_01587	3.15e-201	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HGNGGLLK_01588	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HGNGGLLK_01589	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HGNGGLLK_01590	1.18e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HGNGGLLK_01591	5.13e-267	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGNGGLLK_01592	7.09e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HGNGGLLK_01593	4.51e-148	-	-	-	S	-	-	-	(CBS) domain
HGNGGLLK_01594	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HGNGGLLK_01595	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HGNGGLLK_01596	2.47e-53	yabO	-	-	J	-	-	-	S4 domain protein
HGNGGLLK_01597	5.88e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HGNGGLLK_01598	1.65e-113	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HGNGGLLK_01599	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HGNGGLLK_01600	5.21e-126	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HGNGGLLK_01601	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGNGGLLK_01602	1.93e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HGNGGLLK_01603	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGNGGLLK_01604	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HGNGGLLK_01607	8.34e-101	-	-	-	-	-	-	-	-
HGNGGLLK_01610	3.22e-77	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_01612	4.23e-96	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_01615	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HGNGGLLK_01616	6.8e-291	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_01617	2.23e-257	-	-	-	D	-	-	-	nuclear chromosome segregation
HGNGGLLK_01618	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HGNGGLLK_01619	2.75e-211	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HGNGGLLK_01622	5.68e-150	-	-	-	-	-	-	-	-
HGNGGLLK_01623	1.29e-169	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HGNGGLLK_01624	8.7e-166	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HGNGGLLK_01625	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGNGGLLK_01626	1.15e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HGNGGLLK_01627	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HGNGGLLK_01628	6.97e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HGNGGLLK_01630	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HGNGGLLK_01631	5.3e-240	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HGNGGLLK_01632	8.77e-213	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HGNGGLLK_01633	3.86e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HGNGGLLK_01634	3.23e-215	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HGNGGLLK_01635	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HGNGGLLK_01636	3.45e-144	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HGNGGLLK_01637	1.21e-141	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HGNGGLLK_01638	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_01639	8.16e-304	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_01640	4.65e-72	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HGNGGLLK_01641	3.55e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HGNGGLLK_01642	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HGNGGLLK_01643	4.73e-265	yacL	-	-	S	-	-	-	domain protein
HGNGGLLK_01644	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGNGGLLK_01645	1.64e-67	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HGNGGLLK_01646	2.41e-47	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HGNGGLLK_01647	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HGNGGLLK_01648	1.25e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HGNGGLLK_01649	7.11e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGNGGLLK_01650	5.57e-135	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HGNGGLLK_01651	7.09e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HGNGGLLK_01652	2.48e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HGNGGLLK_01653	8.34e-127	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HGNGGLLK_01654	3.34e-68	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HGNGGLLK_01655	1.68e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HGNGGLLK_01656	5.13e-244	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HGNGGLLK_01657	5.22e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HGNGGLLK_01658	3.88e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HGNGGLLK_01659	8.24e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HGNGGLLK_01660	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HGNGGLLK_01661	4.17e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HGNGGLLK_01662	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HGNGGLLK_01663	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HGNGGLLK_01664	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HGNGGLLK_01665	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HGNGGLLK_01666	2.56e-249	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGNGGLLK_01667	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGNGGLLK_01668	6.56e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HGNGGLLK_01669	1.75e-111	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HGNGGLLK_01671	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGNGGLLK_01672	3.97e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HGNGGLLK_01673	6.48e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HGNGGLLK_01674	2.06e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HGNGGLLK_01675	2.41e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGNGGLLK_01676	2.25e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HGNGGLLK_01677	7.9e-246	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HGNGGLLK_01678	2.47e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HGNGGLLK_01679	2.32e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HGNGGLLK_01680	2.23e-186	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HGNGGLLK_01681	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HGNGGLLK_01682	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HGNGGLLK_01683	1.67e-221	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HGNGGLLK_01684	8.55e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HGNGGLLK_01685	6.98e-206	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
HGNGGLLK_01686	2.08e-239	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGNGGLLK_01687	4.08e-218	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HGNGGLLK_01688	5.72e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HGNGGLLK_01689	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HGNGGLLK_01690	3.8e-31	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HGNGGLLK_01691	3.1e-215	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HGNGGLLK_01692	3.98e-280	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HGNGGLLK_01693	1.61e-274	arcT	-	-	E	-	-	-	Aminotransferase
HGNGGLLK_01694	2.29e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HGNGGLLK_01695	3.08e-140	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HGNGGLLK_01696	3.65e-250	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HGNGGLLK_01698	3.83e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HGNGGLLK_01699	1.32e-97	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HGNGGLLK_01700	6.51e-220	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGNGGLLK_01701	4.18e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGNGGLLK_01702	1.86e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HGNGGLLK_01703	1.09e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HGNGGLLK_01704	1.32e-291	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HGNGGLLK_01705	3.46e-94	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HGNGGLLK_01706	1.13e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HGNGGLLK_01707	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HGNGGLLK_01708	2.25e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HGNGGLLK_01709	4.46e-180	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HGNGGLLK_01710	1.55e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HGNGGLLK_01711	3.37e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HGNGGLLK_01712	1.04e-224	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HGNGGLLK_01713	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HGNGGLLK_01714	8.05e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HGNGGLLK_01715	1.15e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HGNGGLLK_01716	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HGNGGLLK_01717	0.0	ydaO	-	-	E	-	-	-	amino acid
HGNGGLLK_01718	4.12e-50	-	-	-	-	-	-	-	-
HGNGGLLK_01719	2.32e-146	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HGNGGLLK_01720	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HGNGGLLK_01721	6.17e-166	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HGNGGLLK_01722	4.64e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HGNGGLLK_01723	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HGNGGLLK_01724	5.89e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HGNGGLLK_01725	1.97e-70	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HGNGGLLK_01726	4.15e-69	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HGNGGLLK_01727	5.87e-228	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HGNGGLLK_01728	1.08e-208	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HGNGGLLK_01729	3.7e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HGNGGLLK_01730	7.64e-220	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HGNGGLLK_01731	8.38e-186	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HGNGGLLK_01732	1.79e-288	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HGNGGLLK_01733	1.25e-240	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGNGGLLK_01734	5.48e-102	yphH	-	-	S	-	-	-	Cupin domain
HGNGGLLK_01735	8.22e-167	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HGNGGLLK_01736	1.4e-199	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HGNGGLLK_01737	4.22e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HGNGGLLK_01738	1.38e-20	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HGNGGLLK_01739	8.97e-37	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HGNGGLLK_01740	2.39e-254	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HGNGGLLK_01741	1.59e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HGNGGLLK_01742	1.7e-175	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HGNGGLLK_01743	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HGNGGLLK_01744	1.02e-144	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HGNGGLLK_01746	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HGNGGLLK_01747	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HGNGGLLK_01748	1.25e-261	-	-	-	-	-	-	-	-
HGNGGLLK_01749	3.72e-204	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HGNGGLLK_01750	2e-240	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HGNGGLLK_01751	2.34e-214	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HGNGGLLK_01752	1.77e-156	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HGNGGLLK_01753	2.96e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HGNGGLLK_01757	3.82e-23	-	-	-	-	-	-	-	-
HGNGGLLK_01758	2.64e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGNGGLLK_01759	1.72e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HGNGGLLK_01760	2.4e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGNGGLLK_01761	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HGNGGLLK_01762	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HGNGGLLK_01763	1.35e-164	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_01764	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HGNGGLLK_01765	6.82e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HGNGGLLK_01766	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HGNGGLLK_01767	4.66e-110	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HGNGGLLK_01768	1.66e-139	-	-	-	-	-	-	-	-
HGNGGLLK_01769	4.52e-175	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HGNGGLLK_01770	9.74e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HGNGGLLK_01771	4.21e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HGNGGLLK_01772	1.3e-116	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HGNGGLLK_01773	6.64e-132	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HGNGGLLK_01774	2.34e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HGNGGLLK_01775	1.61e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGNGGLLK_01776	1.69e-151	ybbR	-	-	S	-	-	-	YbbR-like protein
HGNGGLLK_01777	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGNGGLLK_01778	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HGNGGLLK_01779	2.55e-68	-	-	-	-	-	-	-	-
HGNGGLLK_01780	2.9e-263	oatA	-	-	I	-	-	-	Acyltransferase
HGNGGLLK_01781	8.67e-193	XK27_02985	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HGNGGLLK_01782	7.87e-112	lytE	-	-	M	-	-	-	Lysin motif
HGNGGLLK_01783	6.96e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HGNGGLLK_01784	4.95e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HGNGGLLK_01785	9.48e-165	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HGNGGLLK_01786	2.31e-193	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
HGNGGLLK_01787	8.77e-117	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HGNGGLLK_01788	1.5e-231	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HGNGGLLK_01789	4.48e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HGNGGLLK_01790	2.38e-164	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HGNGGLLK_01791	1.37e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HGNGGLLK_01792	1.8e-76	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HGNGGLLK_01794	1.39e-170	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HGNGGLLK_01795	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HGNGGLLK_01796	1.44e-195	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HGNGGLLK_01797	3.8e-31	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HGNGGLLK_01798	4.93e-212	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HGNGGLLK_01799	9.36e-101	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGNGGLLK_01800	8.28e-292	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_01801	1.88e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
HGNGGLLK_01802	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HGNGGLLK_01803	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HGNGGLLK_01805	5.74e-93	-	-	-	K	-	-	-	GNAT family
HGNGGLLK_01806	5.19e-158	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HGNGGLLK_01807	9.18e-206	yvgN	-	-	S	-	-	-	Aldo keto reductase
HGNGGLLK_01808	5.46e-186	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGNGGLLK_01809	6.37e-169	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HGNGGLLK_01811	2.67e-75	-	-	-	-	-	-	-	-
HGNGGLLK_01813	3.24e-10	-	-	-	-	-	-	-	-
HGNGGLLK_01814	1.02e-102	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
HGNGGLLK_01815	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_01816	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HGNGGLLK_01817	3.22e-246	ampC	-	-	V	-	-	-	Beta-lactamase
HGNGGLLK_01818	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGNGGLLK_01819	2.31e-63	-	-	-	-	-	-	-	-
HGNGGLLK_01820	7.49e-181	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HGNGGLLK_01821	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HGNGGLLK_01822	1.78e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HGNGGLLK_01823	5.36e-208	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HGNGGLLK_01824	1.11e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HGNGGLLK_01825	8.28e-251	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HGNGGLLK_01826	2.12e-292	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HGNGGLLK_01827	3.86e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HGNGGLLK_01828	2e-252	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HGNGGLLK_01829	2.24e-164	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HGNGGLLK_01830	1.1e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HGNGGLLK_01831	5.66e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HGNGGLLK_01832	2.13e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGNGGLLK_01833	2.37e-81	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HGNGGLLK_01834	4.1e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGNGGLLK_01835	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HGNGGLLK_01836	1.78e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HGNGGLLK_01837	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HGNGGLLK_01838	1.19e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HGNGGLLK_01839	8.07e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HGNGGLLK_01840	2.4e-278	-	-	-	M	-	-	-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HGNGGLLK_01841	5.45e-233	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HGNGGLLK_01842	7.67e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HGNGGLLK_01843	5.09e-283	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HGNGGLLK_01845	1.15e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HGNGGLLK_01846	5.85e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HGNGGLLK_01847	6.8e-316	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGNGGLLK_01848	1.7e-195	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HGNGGLLK_01849	6.08e-107	uspA	-	-	T	-	-	-	universal stress protein
HGNGGLLK_01851	1.3e-300	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HGNGGLLK_01852	8.04e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HGNGGLLK_01853	1.52e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
HGNGGLLK_01854	2.3e-173	-	-	-	S	-	-	-	Membrane
HGNGGLLK_01855	7.09e-189	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HGNGGLLK_01856	1.25e-15	-	-	-	S	-	-	-	YjcQ protein
HGNGGLLK_01858	5.1e-140	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HGNGGLLK_01859	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HGNGGLLK_01860	3.37e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HGNGGLLK_01861	2.03e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGNGGLLK_01862	1.61e-277	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HGNGGLLK_01863	3.17e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HGNGGLLK_01864	5.07e-43	-	-	-	M	-	-	-	LysM domain
HGNGGLLK_01865	1.61e-52	-	-	-	-	-	-	-	-
HGNGGLLK_01866	1.74e-49	-	-	-	S	-	-	-	zinc-ribbon domain
HGNGGLLK_01870	3.11e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HGNGGLLK_01871	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HGNGGLLK_01872	4e-314	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HGNGGLLK_01873	5.3e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HGNGGLLK_01874	1.56e-231	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HGNGGLLK_01875	1.95e-187	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HGNGGLLK_01876	2.59e-119	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HGNGGLLK_01877	3.81e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HGNGGLLK_01878	4.86e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_01879	1.65e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HGNGGLLK_01880	1.34e-297	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HGNGGLLK_01881	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HGNGGLLK_01882	1.64e-151	-	-	-	S	-	-	-	Helix-turn-helix domain
HGNGGLLK_01883	1.79e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGNGGLLK_01884	1.62e-293	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HGNGGLLK_01885	7.88e-245	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HGNGGLLK_01886	2.27e-305	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HGNGGLLK_01887	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HGNGGLLK_01888	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HGNGGLLK_01889	5.09e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HGNGGLLK_01890	3.61e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HGNGGLLK_01891	8.89e-226	-	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	queuine tRNA-ribosyltransferase activity
HGNGGLLK_01892	1.5e-66	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HGNGGLLK_01893	2.3e-229	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HGNGGLLK_01894	1.7e-300	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HGNGGLLK_01895	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HGNGGLLK_01896	1.06e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HGNGGLLK_01897	4.97e-97	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HGNGGLLK_01898	7.75e-53	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HGNGGLLK_01899	3.2e-211	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGNGGLLK_01900	2.23e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
HGNGGLLK_01901	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HGNGGLLK_01902	1.37e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HGNGGLLK_01903	7.25e-284	-	-	-	P	-	-	-	Chloride transporter, ClC family
HGNGGLLK_01904	1.44e-122	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HGNGGLLK_01905	6.11e-188	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HGNGGLLK_01906	2.65e-140	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HGNGGLLK_01907	3.33e-123	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HGNGGLLK_01908	1.75e-193	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HGNGGLLK_01909	4.32e-200	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HGNGGLLK_01910	5.99e-67	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HGNGGLLK_01911	4.62e-92	-	-	-	-	-	-	-	-
HGNGGLLK_01912	1.08e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HGNGGLLK_01913	5.94e-238	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HGNGGLLK_01914	6.95e-182	-	-	-	-	-	-	-	-
HGNGGLLK_01915	5.01e-172	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HGNGGLLK_01916	2.09e-119	-	-	-	M	-	-	-	PFAM NLP P60 protein
HGNGGLLK_01917	1.22e-185	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HGNGGLLK_01918	6.2e-226	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HGNGGLLK_01919	1.33e-228	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HGNGGLLK_01920	2.13e-212	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HGNGGLLK_01921	8.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HGNGGLLK_01926	8.77e-203	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HGNGGLLK_01927	6.46e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGNGGLLK_01928	2.73e-147	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HGNGGLLK_01929	3.84e-126	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HGNGGLLK_01930	3.39e-181	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HGNGGLLK_01931	2.65e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HGNGGLLK_01932	8.3e-142	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HGNGGLLK_01933	3.4e-100	-	-	-	-	-	-	-	-
HGNGGLLK_01954	1.12e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HGNGGLLK_01955	8.81e-152	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HGNGGLLK_01956	4.85e-262	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HGNGGLLK_01957	2.52e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HGNGGLLK_01958	5.24e-159	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HGNGGLLK_01959	9.49e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGNGGLLK_01960	5.39e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HGNGGLLK_01961	1.61e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HGNGGLLK_01962	3.9e-208	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HGNGGLLK_01963	2.01e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HGNGGLLK_01964	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HGNGGLLK_01965	4.5e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HGNGGLLK_01966	6.91e-76	-	-	-	-	-	-	-	-
HGNGGLLK_01967	8.95e-103	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HGNGGLLK_01968	5.37e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HGNGGLLK_01969	3.03e-30	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HGNGGLLK_01970	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HGNGGLLK_01971	1.28e-226	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HGNGGLLK_01972	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HGNGGLLK_01973	5.66e-257	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HGNGGLLK_01974	5.43e-193	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HGNGGLLK_01975	4.88e-300	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HGNGGLLK_01976	1.49e-292	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HGNGGLLK_01977	6.1e-101	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HGNGGLLK_01978	7.27e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HGNGGLLK_01979	1.75e-186	ylmH	-	-	S	-	-	-	S4 domain protein
HGNGGLLK_01980	6.19e-143	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HGNGGLLK_01982	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HGNGGLLK_01983	9.99e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HGNGGLLK_01984	1.28e-126	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HGNGGLLK_01986	1.33e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HGNGGLLK_01987	7.86e-77	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HGNGGLLK_01988	3.43e-283	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HGNGGLLK_01989	0.0	-	-	-	S	-	-	-	amidohydrolase
HGNGGLLK_01990	1.08e-218	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HGNGGLLK_01991	1.11e-156	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HGNGGLLK_01992	9.37e-159	-	-	-	S	-	-	-	repeat protein
HGNGGLLK_01993	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HGNGGLLK_01994	3.81e-228	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGNGGLLK_01995	2.39e-98	-	-	-	P	-	-	-	ArsC family
HGNGGLLK_01996	2.95e-239	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
HGNGGLLK_01997	8.83e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HGNGGLLK_01998	6.12e-98	-	-	-	-	-	-	-	-
HGNGGLLK_01999	8.59e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGNGGLLK_02000	1.55e-65	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HGNGGLLK_02001	1.96e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HGNGGLLK_02002	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HGNGGLLK_02003	1.02e-277	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HGNGGLLK_02004	1.31e-63	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HGNGGLLK_02005	1.27e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HGNGGLLK_02006	2.06e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HGNGGLLK_02007	2.29e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HGNGGLLK_02008	1.47e-127	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HGNGGLLK_02009	8.66e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HGNGGLLK_02010	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HGNGGLLK_02011	1.63e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HGNGGLLK_02012	2.9e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HGNGGLLK_02013	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HGNGGLLK_02014	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HGNGGLLK_02015	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGNGGLLK_02016	1.15e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
HGNGGLLK_02017	9.97e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HGNGGLLK_02018	1.15e-299	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HGNGGLLK_02019	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HGNGGLLK_02020	5.34e-140	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HGNGGLLK_02021	1.84e-68	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HGNGGLLK_02023	3.97e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HGNGGLLK_02024	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HGNGGLLK_02025	9.56e-317	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HGNGGLLK_02026	2.48e-224	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HGNGGLLK_02027	1.3e-199	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HGNGGLLK_02028	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HGNGGLLK_02029	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HGNGGLLK_02030	1.64e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HGNGGLLK_02031	7.82e-239	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGNGGLLK_02032	1.51e-193	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HGNGGLLK_02033	1.47e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_02034	2.34e-303	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HGNGGLLK_02035	1.34e-126	ydeQ	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
HGNGGLLK_02036	2.05e-59	-	-	-	S	-	-	-	Protein conserved in bacteria
HGNGGLLK_02037	3.03e-74	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HGNGGLLK_02038	1.29e-66	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HGNGGLLK_02039	2.47e-13	-	-	-	K	-	-	-	transcriptional
HGNGGLLK_02040	2.48e-253	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
HGNGGLLK_02041	1.48e-219	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGNGGLLK_02042	1.21e-118	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
HGNGGLLK_02043	1.41e-132	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HGNGGLLK_02044	9.29e-86	-	-	-	P	-	-	-	Voltage gated chloride channel
HGNGGLLK_02045	6.8e-291	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_02046	1.73e-218	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGNGGLLK_02047	6.3e-163	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HGNGGLLK_02050	5.07e-241	-	-	-	EGP	-	-	-	Major Facilitator
HGNGGLLK_02052	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
HGNGGLLK_02054	3.94e-14	-	-	-	S	-	-	-	CHY zinc finger
HGNGGLLK_02057	2.09e-22	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HGNGGLLK_02059	4.88e-236	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HGNGGLLK_02060	9.97e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HGNGGLLK_02061	4.72e-128	-	-	-	-	-	-	-	-
HGNGGLLK_02063	2.54e-248	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HGNGGLLK_02064	1.43e-99	-	-	-	-	-	-	-	-
HGNGGLLK_02066	6.12e-10	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HGNGGLLK_02067	1.82e-313	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGNGGLLK_02068	3.8e-222	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGNGGLLK_02069	2.99e-34	ybeC	-	-	E	-	-	-	amino acid
HGNGGLLK_02070	6.8e-291	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_02071	0.0	ybeC	-	-	E	-	-	-	amino acid
HGNGGLLK_02072	3.8e-222	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGNGGLLK_02073	9.29e-138	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HGNGGLLK_02074	2.2e-66	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HGNGGLLK_02075	1.94e-86	-	-	-	-	-	-	-	-
HGNGGLLK_02076	1.58e-70	-	-	-	-	-	-	-	-
HGNGGLLK_02077	1.7e-280	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
HGNGGLLK_02078	2e-300	yagE	-	-	E	-	-	-	Amino acid permease
HGNGGLLK_02079	1.24e-165	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HGNGGLLK_02080	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HGNGGLLK_02081	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HGNGGLLK_02083	1.97e-211	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HGNGGLLK_02084	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
HGNGGLLK_02085	1.04e-205	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HGNGGLLK_02086	2.37e-167	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HGNGGLLK_02087	1.72e-08	-	-	-	-	-	-	-	-
HGNGGLLK_02088	1.15e-20	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_02089	2.45e-56	-	-	-	S	-	-	-	SEFIR domain
HGNGGLLK_02090	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HGNGGLLK_02093	3.61e-132	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HGNGGLLK_02094	5.15e-247	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HGNGGLLK_02095	2.43e-98	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HGNGGLLK_02098	1.63e-82	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HGNGGLLK_02099	1.26e-140	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HGNGGLLK_02100	1.74e-34	yitW	-	-	S	-	-	-	DNA methyltransferase
HGNGGLLK_02101	2.07e-46	-	-	-	M	-	-	-	domain protein
HGNGGLLK_02103	4.96e-68	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HGNGGLLK_02104	7.68e-28	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HGNGGLLK_02105	1.85e-108	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HGNGGLLK_02106	6.16e-307	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HGNGGLLK_02107	2.76e-155	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HGNGGLLK_02108	4.27e-74	-	-	-	L	-	-	-	Helix-turn-helix domain
HGNGGLLK_02109	2.28e-117	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HGNGGLLK_02110	5.95e-219	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HGNGGLLK_02111	8.74e-314	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HGNGGLLK_02112	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
HGNGGLLK_02113	2.56e-217	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HGNGGLLK_02114	7.05e-272	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_02115	0.000572	-	-	-	-	-	-	-	-
HGNGGLLK_02116	2.07e-58	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HGNGGLLK_02117	7.81e-193	traA	-	-	L	-	-	-	MobA MobL family protein
HGNGGLLK_02118	4.03e-37	-	-	-	-	-	-	-	-
HGNGGLLK_02119	2.01e-53	-	-	-	-	-	-	-	-
HGNGGLLK_02120	2.13e-158	-	-	-	S	-	-	-	protein conserved in bacteria
HGNGGLLK_02121	5.93e-37	-	-	-	-	-	-	-	-
HGNGGLLK_02122	4.7e-57	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HGNGGLLK_02123	2.58e-181	-	-	-	D	-	-	-	AAA domain
HGNGGLLK_02124	4.07e-39	-	-	-	-	-	-	-	-
HGNGGLLK_02125	4.56e-77	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_02126	4.65e-66	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HGNGGLLK_02127	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
HGNGGLLK_02129	9.26e-307	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGNGGLLK_02132	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HGNGGLLK_02133	1.24e-71	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
HGNGGLLK_02134	1.9e-97	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
HGNGGLLK_02135	1.94e-86	-	-	-	-	-	-	-	-
HGNGGLLK_02136	5.12e-96	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HGNGGLLK_02138	3.17e-43	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_02139	2.6e-75	-	-	-	L	-	-	-	Helix-turn-helix domain
HGNGGLLK_02140	2.28e-117	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HGNGGLLK_02141	5.95e-219	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HGNGGLLK_02142	8.74e-314	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HGNGGLLK_02143	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
HGNGGLLK_02144	4.42e-218	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HGNGGLLK_02145	7.05e-272	-	-	-	L	-	-	-	MULE transposase domain
HGNGGLLK_02146	0.000572	-	-	-	-	-	-	-	-
HGNGGLLK_02147	2.07e-58	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HGNGGLLK_02148	7.81e-193	traA	-	-	L	-	-	-	MobA MobL family protein
HGNGGLLK_02149	4.03e-37	-	-	-	-	-	-	-	-
HGNGGLLK_02150	2.01e-53	-	-	-	-	-	-	-	-
HGNGGLLK_02151	2.13e-158	-	-	-	S	-	-	-	protein conserved in bacteria
HGNGGLLK_02152	5.93e-37	-	-	-	-	-	-	-	-
HGNGGLLK_02153	4.7e-57	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HGNGGLLK_02154	2.58e-181	-	-	-	D	-	-	-	AAA domain
HGNGGLLK_02155	4.07e-39	-	-	-	-	-	-	-	-
HGNGGLLK_02156	4.56e-77	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HGNGGLLK_02157	4.65e-66	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HGNGGLLK_02158	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
HGNGGLLK_02160	9.26e-307	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGNGGLLK_02163	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HGNGGLLK_02164	1.24e-71	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
HGNGGLLK_02165	1.9e-97	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
HGNGGLLK_02166	3.62e-46	-	-	-	-	-	-	-	-
HGNGGLLK_02167	5.12e-96	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed