ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
IANDFCOA_00001 5.55e-301 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IANDFCOA_00002 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IANDFCOA_00003 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
IANDFCOA_00004 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IANDFCOA_00005 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
IANDFCOA_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IANDFCOA_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IANDFCOA_00008 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IANDFCOA_00011 2.14e-232 yaaC - - S - - - YaaC-like Protein
IANDFCOA_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IANDFCOA_00013 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IANDFCOA_00014 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IANDFCOA_00015 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IANDFCOA_00016 6.6e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IANDFCOA_00018 2.15e-158 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
IANDFCOA_00019 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
IANDFCOA_00020 2.99e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
IANDFCOA_00021 1.89e-123 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
IANDFCOA_00022 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IANDFCOA_00023 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IANDFCOA_00024 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IANDFCOA_00025 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IANDFCOA_00026 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
IANDFCOA_00027 6.2e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
IANDFCOA_00028 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IANDFCOA_00031 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
IANDFCOA_00032 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IANDFCOA_00033 8.37e-259 yaaN - - P - - - Belongs to the TelA family
IANDFCOA_00034 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
IANDFCOA_00035 2.82e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IANDFCOA_00036 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
IANDFCOA_00037 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
IANDFCOA_00038 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IANDFCOA_00039 1.1e-189 yaaT - - S - - - stage 0 sporulation protein
IANDFCOA_00040 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
IANDFCOA_00041 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
IANDFCOA_00042 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
IANDFCOA_00043 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IANDFCOA_00044 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
IANDFCOA_00045 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IANDFCOA_00046 4.85e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
IANDFCOA_00047 1.18e-277 yabE - - T - - - protein conserved in bacteria
IANDFCOA_00048 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IANDFCOA_00049 5.04e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IANDFCOA_00050 1.84e-197 yabG - - S ko:K06436 - ko00000 peptidase
IANDFCOA_00051 5.32e-53 veg - - S - - - protein conserved in bacteria
IANDFCOA_00052 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
IANDFCOA_00053 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IANDFCOA_00054 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
IANDFCOA_00055 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
IANDFCOA_00056 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IANDFCOA_00057 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IANDFCOA_00058 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IANDFCOA_00059 9.8e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IANDFCOA_00060 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IANDFCOA_00061 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
IANDFCOA_00062 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IANDFCOA_00063 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
IANDFCOA_00064 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IANDFCOA_00065 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IANDFCOA_00066 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IANDFCOA_00067 1.91e-66 yabP - - S - - - Sporulation protein YabP
IANDFCOA_00068 5.21e-138 yabQ - - S - - - spore cortex biosynthesis protein
IANDFCOA_00069 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
IANDFCOA_00070 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IANDFCOA_00073 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
IANDFCOA_00074 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IANDFCOA_00075 1.63e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
IANDFCOA_00076 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IANDFCOA_00077 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
IANDFCOA_00078 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IANDFCOA_00079 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IANDFCOA_00080 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IANDFCOA_00081 2.72e-195 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
IANDFCOA_00082 1.26e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IANDFCOA_00083 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IANDFCOA_00084 1.72e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
IANDFCOA_00085 1.54e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
IANDFCOA_00086 1.11e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IANDFCOA_00087 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IANDFCOA_00088 9.21e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IANDFCOA_00089 1.81e-41 yazB - - K - - - transcriptional
IANDFCOA_00090 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IANDFCOA_00091 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
IANDFCOA_00092 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IANDFCOA_00102 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IANDFCOA_00103 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
IANDFCOA_00104 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
IANDFCOA_00105 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IANDFCOA_00106 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
IANDFCOA_00107 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IANDFCOA_00108 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IANDFCOA_00109 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
IANDFCOA_00110 4.29e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IANDFCOA_00111 2.59e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IANDFCOA_00112 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IANDFCOA_00113 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
IANDFCOA_00114 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IANDFCOA_00115 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IANDFCOA_00116 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IANDFCOA_00117 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
IANDFCOA_00118 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
IANDFCOA_00119 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IANDFCOA_00120 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IANDFCOA_00121 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IANDFCOA_00122 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IANDFCOA_00123 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IANDFCOA_00124 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IANDFCOA_00125 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
IANDFCOA_00126 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IANDFCOA_00127 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IANDFCOA_00128 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
IANDFCOA_00129 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IANDFCOA_00130 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IANDFCOA_00131 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IANDFCOA_00132 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IANDFCOA_00133 8.68e-229 ybaC - - S - - - Alpha/beta hydrolase family
IANDFCOA_00134 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
IANDFCOA_00135 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IANDFCOA_00136 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
IANDFCOA_00137 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IANDFCOA_00138 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IANDFCOA_00139 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IANDFCOA_00140 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IANDFCOA_00141 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IANDFCOA_00142 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IANDFCOA_00143 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
IANDFCOA_00144 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IANDFCOA_00145 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IANDFCOA_00146 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IANDFCOA_00147 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IANDFCOA_00148 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IANDFCOA_00149 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IANDFCOA_00150 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IANDFCOA_00151 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IANDFCOA_00152 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IANDFCOA_00153 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
IANDFCOA_00154 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IANDFCOA_00155 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IANDFCOA_00156 1.46e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IANDFCOA_00157 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IANDFCOA_00158 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IANDFCOA_00159 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
IANDFCOA_00160 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IANDFCOA_00161 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IANDFCOA_00162 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IANDFCOA_00163 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
IANDFCOA_00164 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IANDFCOA_00165 1.28e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IANDFCOA_00166 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IANDFCOA_00167 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IANDFCOA_00168 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IANDFCOA_00169 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
IANDFCOA_00170 2.14e-186 ybaJ - - Q - - - Methyltransferase domain
IANDFCOA_00171 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
IANDFCOA_00172 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IANDFCOA_00173 4.47e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IANDFCOA_00174 1.04e-122 gerD - - - ko:K06294 - ko00000 -
IANDFCOA_00175 2.42e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
IANDFCOA_00176 2.49e-180 pdaB - - G - - - Polysaccharide deacetylase
IANDFCOA_00177 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IANDFCOA_00184 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IANDFCOA_00185 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IANDFCOA_00186 2.61e-316 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IANDFCOA_00188 5.36e-203 ybaS - - S - - - Na -dependent transporter
IANDFCOA_00189 5.87e-177 ybbA - - S ko:K07017 - ko00000 Putative esterase
IANDFCOA_00190 2.37e-226 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IANDFCOA_00191 1.17e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IANDFCOA_00192 1.26e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
IANDFCOA_00193 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
IANDFCOA_00194 4.71e-302 ybbC - - S - - - protein conserved in bacteria
IANDFCOA_00195 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
IANDFCOA_00196 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
IANDFCOA_00197 1.04e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IANDFCOA_00198 3.01e-191 ybbH - - K - - - transcriptional
IANDFCOA_00199 1.11e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IANDFCOA_00200 1.81e-113 ybbJ - - J - - - acetyltransferase
IANDFCOA_00201 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
IANDFCOA_00207 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IANDFCOA_00208 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IANDFCOA_00209 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IANDFCOA_00210 3.41e-291 ybbR - - S - - - protein conserved in bacteria
IANDFCOA_00211 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IANDFCOA_00212 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IANDFCOA_00213 5.38e-220 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IANDFCOA_00214 1.71e-152 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
IANDFCOA_00215 1.06e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IANDFCOA_00216 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IANDFCOA_00217 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
IANDFCOA_00218 1.83e-118 ybcF - - P - - - carbonic anhydrase
IANDFCOA_00219 1.6e-63 - - - - - - - -
IANDFCOA_00220 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
IANDFCOA_00222 9.45e-67 - - - K - - - Helix-turn-helix domain
IANDFCOA_00223 1.81e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
IANDFCOA_00225 1.21e-21 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IANDFCOA_00226 7.04e-139 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
IANDFCOA_00227 6.48e-50 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C family protein
IANDFCOA_00229 6.47e-176 abcA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
IANDFCOA_00230 2.31e-232 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IANDFCOA_00231 3.28e-156 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
IANDFCOA_00232 1.61e-218 - - - T - - - His Kinase A (phospho-acceptor) domain
IANDFCOA_00234 3.26e-177 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
IANDFCOA_00235 7.4e-193 ybdN - - - - - - -
IANDFCOA_00236 1.22e-271 ybdO - - S - - - Domain of unknown function (DUF4885)
IANDFCOA_00237 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IANDFCOA_00238 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
IANDFCOA_00239 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
IANDFCOA_00240 1.06e-192 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
IANDFCOA_00241 3.64e-312 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
IANDFCOA_00242 1.11e-54 ybyB - - - - - - -
IANDFCOA_00243 0.0 ybeC - - E - - - amino acid
IANDFCOA_00244 2.85e-210 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
IANDFCOA_00245 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
IANDFCOA_00246 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
IANDFCOA_00247 2.1e-218 ybfA - - K - - - FR47-like protein
IANDFCOA_00248 2.75e-286 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
IANDFCOA_00250 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
IANDFCOA_00251 5.27e-208 ybfH - - EG - - - EamA-like transporter family
IANDFCOA_00252 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
IANDFCOA_00253 5.85e-274 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IANDFCOA_00254 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
IANDFCOA_00256 2.02e-216 - - - S - - - Alpha/beta hydrolase family
IANDFCOA_00257 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IANDFCOA_00258 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
IANDFCOA_00259 4.33e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IANDFCOA_00260 1.58e-59 ybfN - - - - - - -
IANDFCOA_00261 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
IANDFCOA_00262 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IANDFCOA_00263 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IANDFCOA_00264 5.22e-175 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IANDFCOA_00265 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
IANDFCOA_00267 3.74e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IANDFCOA_00268 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IANDFCOA_00269 5.26e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
IANDFCOA_00270 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IANDFCOA_00271 8.78e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IANDFCOA_00272 1.19e-292 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_00273 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
IANDFCOA_00274 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
IANDFCOA_00275 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IANDFCOA_00276 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IANDFCOA_00277 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IANDFCOA_00278 4.63e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
IANDFCOA_00279 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
IANDFCOA_00280 2.47e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
IANDFCOA_00281 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
IANDFCOA_00282 7.31e-218 eamA1 - - EG - - - spore germination
IANDFCOA_00283 3.71e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IANDFCOA_00284 6.21e-214 ycbM - - T - - - Histidine kinase
IANDFCOA_00285 1.66e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_00286 2.87e-148 - - - S - - - ABC-2 family transporter protein
IANDFCOA_00287 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
IANDFCOA_00288 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
IANDFCOA_00289 5.44e-174 ycbR - - T - - - vWA found in TerF C terminus
IANDFCOA_00290 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
IANDFCOA_00291 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IANDFCOA_00292 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IANDFCOA_00293 9.85e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IANDFCOA_00294 4.86e-259 ycbU - - E - - - Selenocysteine lyase
IANDFCOA_00295 2.51e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
IANDFCOA_00296 1.88e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IANDFCOA_00297 1.97e-256 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IANDFCOA_00298 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
IANDFCOA_00299 4.32e-78 - - - S - - - RDD family
IANDFCOA_00300 1.01e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
IANDFCOA_00301 1.77e-212 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IANDFCOA_00302 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
IANDFCOA_00303 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
IANDFCOA_00304 5.64e-257 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IANDFCOA_00305 6.81e-222 yccK - - C - - - Aldo keto reductase
IANDFCOA_00306 1.92e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
IANDFCOA_00307 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IANDFCOA_00308 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IANDFCOA_00309 2.65e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IANDFCOA_00310 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
IANDFCOA_00311 1.96e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
IANDFCOA_00312 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IANDFCOA_00313 2.27e-220 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IANDFCOA_00314 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IANDFCOA_00315 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IANDFCOA_00316 5.95e-238 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IANDFCOA_00317 2.17e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
IANDFCOA_00318 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IANDFCOA_00319 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IANDFCOA_00320 1.37e-174 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
IANDFCOA_00321 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
IANDFCOA_00322 2.96e-245 yceH - - P - - - Belongs to the TelA family
IANDFCOA_00323 3.84e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
IANDFCOA_00324 1.3e-264 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
IANDFCOA_00325 1.97e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IANDFCOA_00326 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
IANDFCOA_00327 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IANDFCOA_00328 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IANDFCOA_00329 1.97e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
IANDFCOA_00330 0.0 ycgA - - S - - - Membrane
IANDFCOA_00331 2.72e-105 ycgB - - - - - - -
IANDFCOA_00332 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
IANDFCOA_00333 9.79e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IANDFCOA_00334 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IANDFCOA_00335 0.0 mdr - - EGP - - - the major facilitator superfamily
IANDFCOA_00336 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
IANDFCOA_00337 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
IANDFCOA_00338 2.07e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
IANDFCOA_00339 9.32e-317 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IANDFCOA_00340 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
IANDFCOA_00341 5.24e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IANDFCOA_00342 1.43e-53 tmrB - - S - - - AAA domain
IANDFCOA_00343 2.39e-22 tmrB - - S - - - AAA domain
IANDFCOA_00345 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IANDFCOA_00346 1.02e-183 - - - Q - - - ubiE/COQ5 methyltransferase family
IANDFCOA_00347 5.4e-226 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
IANDFCOA_00348 3.16e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
IANDFCOA_00349 1.75e-183 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
IANDFCOA_00350 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IANDFCOA_00351 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IANDFCOA_00352 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IANDFCOA_00353 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
IANDFCOA_00354 7.72e-195 ycgQ - - S ko:K08986 - ko00000 membrane
IANDFCOA_00355 2.41e-184 ycgR - - S ko:K07089 - ko00000 permeases
IANDFCOA_00356 2.32e-200 ycgS - - I - - - alpha/beta hydrolase fold
IANDFCOA_00357 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
IANDFCOA_00358 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IANDFCOA_00359 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
IANDFCOA_00360 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IANDFCOA_00361 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IANDFCOA_00362 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
IANDFCOA_00363 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IANDFCOA_00364 1.08e-215 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
IANDFCOA_00365 1.04e-140 - - - M - - - ErfK YbiS YcfS YnhG
IANDFCOA_00366 3.76e-288 yciC - - S - - - GTPases (G3E family)
IANDFCOA_00367 9.69e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IANDFCOA_00368 7.26e-185 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IANDFCOA_00371 1.29e-95 yckC - - S - - - membrane
IANDFCOA_00372 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
IANDFCOA_00373 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IANDFCOA_00374 4.78e-91 nin - - S - - - Competence protein J (ComJ)
IANDFCOA_00375 3.23e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
IANDFCOA_00376 1.86e-268 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IANDFCOA_00377 1.13e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
IANDFCOA_00378 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
IANDFCOA_00379 6.05e-86 hxlR - - K - - - transcriptional
IANDFCOA_00380 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IANDFCOA_00381 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IANDFCOA_00382 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
IANDFCOA_00383 2.71e-178 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
IANDFCOA_00384 6.53e-290 - - - EGP - - - Major Facilitator Superfamily
IANDFCOA_00385 2.87e-120 - - - S - - - YcxB-like protein
IANDFCOA_00386 7.69e-204 ycxC - - EG - - - EamA-like transporter family
IANDFCOA_00387 0.0 ycxD - - K - - - GntR family transcriptional regulator
IANDFCOA_00388 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
IANDFCOA_00389 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
IANDFCOA_00390 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IANDFCOA_00391 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IANDFCOA_00392 2.49e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
IANDFCOA_00393 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
IANDFCOA_00394 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IANDFCOA_00395 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IANDFCOA_00396 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
IANDFCOA_00397 1.34e-103 yclD - - - - - - -
IANDFCOA_00398 7.82e-202 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
IANDFCOA_00399 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
IANDFCOA_00400 0.0 yclG - - M - - - Pectate lyase superfamily protein
IANDFCOA_00402 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
IANDFCOA_00403 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
IANDFCOA_00404 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
IANDFCOA_00405 2.05e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IANDFCOA_00406 2.27e-279 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
IANDFCOA_00407 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IANDFCOA_00408 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IANDFCOA_00409 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IANDFCOA_00411 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IANDFCOA_00412 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IANDFCOA_00413 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IANDFCOA_00414 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IANDFCOA_00415 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_00416 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
IANDFCOA_00417 1.18e-96 - - - V - - - Restriction endonuclease
IANDFCOA_00418 0.0 ycnB - - EGP - - - the major facilitator superfamily
IANDFCOA_00419 5.87e-198 ycnC - - K - - - Transcriptional regulator
IANDFCOA_00420 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IANDFCOA_00421 1.68e-60 ycnE - - S - - - Monooxygenase
IANDFCOA_00422 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IANDFCOA_00423 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IANDFCOA_00424 4.64e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IANDFCOA_00425 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IANDFCOA_00426 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
IANDFCOA_00427 1.19e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IANDFCOA_00428 3.99e-134 ycnI - - S - - - protein conserved in bacteria
IANDFCOA_00429 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
IANDFCOA_00430 1.22e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IANDFCOA_00431 1.34e-74 - - - - - - - -
IANDFCOA_00432 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
IANDFCOA_00433 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IANDFCOA_00434 2.97e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
IANDFCOA_00435 1.68e-255 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
IANDFCOA_00437 1.78e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IANDFCOA_00438 1.71e-143 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
IANDFCOA_00439 1.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
IANDFCOA_00441 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IANDFCOA_00442 3.82e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
IANDFCOA_00443 1.87e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
IANDFCOA_00444 7.45e-20 ycsI - - S - - - Belongs to the D-glutamate cyclase family
IANDFCOA_00445 1.68e-144 ycsI - - S - - - Belongs to the D-glutamate cyclase family
IANDFCOA_00446 2.05e-172 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
IANDFCOA_00447 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
IANDFCOA_00448 1.55e-170 kipR - - K - - - Transcriptional regulator
IANDFCOA_00449 5.94e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
IANDFCOA_00451 8.97e-65 yczJ - - S - - - biosynthesis
IANDFCOA_00452 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
IANDFCOA_00453 8.6e-220 ycsN - - S - - - Oxidoreductase
IANDFCOA_00454 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
IANDFCOA_00455 0.0 ydaB - - IQ - - - acyl-CoA ligase
IANDFCOA_00456 1e-127 ydaC - - Q - - - Methyltransferase domain
IANDFCOA_00457 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IANDFCOA_00458 2.75e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
IANDFCOA_00459 2.69e-133 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IANDFCOA_00460 5.24e-101 ydaG - - S - - - general stress protein
IANDFCOA_00461 1.31e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IANDFCOA_00462 1.88e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
IANDFCOA_00463 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IANDFCOA_00464 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IANDFCOA_00465 6.96e-264 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
IANDFCOA_00466 3.66e-192 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
IANDFCOA_00467 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
IANDFCOA_00468 7.86e-304 ydaM - - M - - - Glycosyl transferase family group 2
IANDFCOA_00469 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
IANDFCOA_00470 0.0 ydaO - - E - - - amino acid
IANDFCOA_00471 3.08e-102 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IANDFCOA_00472 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IANDFCOA_00473 2.14e-53 - - - - - - - -
IANDFCOA_00474 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IANDFCOA_00475 1.67e-42 ydaS - - S - - - membrane
IANDFCOA_00476 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
IANDFCOA_00477 1.75e-189 ydbA - - P - - - EcsC protein family
IANDFCOA_00478 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
IANDFCOA_00479 7.58e-79 ydbB - - G - - - Cupin domain
IANDFCOA_00480 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
IANDFCOA_00481 1.06e-195 ydbD - - P ko:K07217 - ko00000 Catalase
IANDFCOA_00482 1.43e-250 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IANDFCOA_00483 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IANDFCOA_00484 1.38e-154 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IANDFCOA_00485 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IANDFCOA_00486 1.32e-230 ydbI - - S - - - AI-2E family transporter
IANDFCOA_00487 3.23e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_00488 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IANDFCOA_00489 7.67e-69 ydbL - - - - - - -
IANDFCOA_00490 7.45e-280 ydbM - - I - - - acyl-CoA dehydrogenase
IANDFCOA_00492 1.35e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IANDFCOA_00493 4.19e-75 ydbP - - CO - - - Thioredoxin
IANDFCOA_00494 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
IANDFCOA_00495 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IANDFCOA_00496 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IANDFCOA_00497 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
IANDFCOA_00498 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
IANDFCOA_00499 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
IANDFCOA_00500 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IANDFCOA_00501 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
IANDFCOA_00502 5.29e-284 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IANDFCOA_00503 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IANDFCOA_00504 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
IANDFCOA_00505 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
IANDFCOA_00506 7.34e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
IANDFCOA_00507 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IANDFCOA_00508 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
IANDFCOA_00509 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
IANDFCOA_00510 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IANDFCOA_00511 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IANDFCOA_00512 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
IANDFCOA_00516 1.32e-106 ydcG - - S - - - EVE domain
IANDFCOA_00517 1.54e-101 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IANDFCOA_00518 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
IANDFCOA_00519 1.53e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
IANDFCOA_00527 7.32e-92 - - - J - - - Acetyltransferase (GNAT) domain
IANDFCOA_00528 2.85e-58 - - - - - - - -
IANDFCOA_00529 3.85e-24 - - - S ko:K21493 - ko00000,ko01000,ko02048 LXG domain of WXG superfamily
IANDFCOA_00530 8.43e-29 - - - L ko:K07451,ko:K07452 - ko00000,ko01000,ko02048 HNH endonuclease
IANDFCOA_00531 9.05e-56 - - - L - - - HNH nucleases
IANDFCOA_00534 7.24e-08 - - - S - - - Putative amidase domain
IANDFCOA_00537 1.54e-46 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
IANDFCOA_00538 6e-53 - - - - - - - -
IANDFCOA_00542 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
IANDFCOA_00543 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
IANDFCOA_00544 5.92e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
IANDFCOA_00545 3.56e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IANDFCOA_00546 2.18e-213 - - - K - - - AraC-like ligand binding domain
IANDFCOA_00547 2.37e-222 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IANDFCOA_00548 4.94e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
IANDFCOA_00549 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IANDFCOA_00550 5.15e-275 ydeG - - EGP - - - Major facilitator superfamily
IANDFCOA_00551 9.2e-70 ydeH - - - - - - -
IANDFCOA_00552 6.99e-136 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
IANDFCOA_00553 2.46e-140 - - - - - - - -
IANDFCOA_00554 2.79e-100 - - - I - - - Ribosomal RNA adenine dimethylase
IANDFCOA_00555 5.54e-146 - - - T - - - Transcriptional regulator
IANDFCOA_00556 2.65e-176 - - - T - - - COG0642 Signal transduction histidine kinase
IANDFCOA_00557 4.01e-92 - - - S - - - SNARE associated Golgi protein
IANDFCOA_00558 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
IANDFCOA_00559 1.72e-110 - - - K - - - Transcriptional regulator C-terminal region
IANDFCOA_00561 1.49e-193 ydeK - - EG - - - -transporter
IANDFCOA_00562 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IANDFCOA_00563 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
IANDFCOA_00564 2.31e-133 - - - S ko:K07002 - ko00000 Serine hydrolase
IANDFCOA_00565 8.68e-74 - - - K - - - HxlR-like helix-turn-helix
IANDFCOA_00566 1.32e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IANDFCOA_00567 2.92e-90 ydeP - - K - - - Transcriptional regulator
IANDFCOA_00568 2.36e-143 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
IANDFCOA_00569 1.13e-256 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
IANDFCOA_00570 4.73e-133 ydeS - - K - - - Transcriptional regulator
IANDFCOA_00571 1.05e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
IANDFCOA_00572 3.53e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IANDFCOA_00573 2.22e-188 - - - J - - - GNAT acetyltransferase
IANDFCOA_00574 2.5e-206 - - - EG - - - EamA-like transporter family
IANDFCOA_00575 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IANDFCOA_00576 4.71e-148 ydfE - - S - - - Flavin reductase like domain
IANDFCOA_00577 7.44e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IANDFCOA_00578 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IANDFCOA_00580 3.37e-252 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_00581 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IANDFCOA_00582 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
IANDFCOA_00583 4.44e-222 - - - S - - - Alpha/beta hydrolase family
IANDFCOA_00584 7.6e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
IANDFCOA_00585 6.84e-186 - - - K - - - Bacterial transcription activator, effector binding domain
IANDFCOA_00586 5.22e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IANDFCOA_00587 3.45e-145 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
IANDFCOA_00588 9.49e-239 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IANDFCOA_00589 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
IANDFCOA_00590 9.63e-77 ydfQ - - CO - - - Thioredoxin
IANDFCOA_00591 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
IANDFCOA_00592 5.33e-39 - - - - - - - -
IANDFCOA_00594 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
IANDFCOA_00595 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
IANDFCOA_00596 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IANDFCOA_00597 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
IANDFCOA_00598 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
IANDFCOA_00599 5.99e-130 ydgC - - K - - - Bacterial regulatory proteins, tetR family
IANDFCOA_00600 7e-71 - - - S - - - DoxX-like family
IANDFCOA_00601 2.49e-114 yycN - - K - - - Acetyltransferase
IANDFCOA_00602 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
IANDFCOA_00603 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IANDFCOA_00604 5.94e-118 - - - S - - - DinB family
IANDFCOA_00605 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IANDFCOA_00606 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
IANDFCOA_00607 2.15e-145 ydgI - - C - - - nitroreductase
IANDFCOA_00608 1.9e-89 - - - K - - - Winged helix DNA-binding domain
IANDFCOA_00609 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
IANDFCOA_00610 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
IANDFCOA_00611 5.24e-158 ydhC - - K - - - FCD
IANDFCOA_00612 8.92e-310 ydhD - - M - - - Glycosyl hydrolase
IANDFCOA_00613 9.61e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IANDFCOA_00614 7.71e-166 - - - - - - - -
IANDFCOA_00615 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
IANDFCOA_00616 2.26e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IANDFCOA_00618 1.43e-112 - - - K - - - Acetyltransferase (GNAT) domain
IANDFCOA_00619 4.67e-232 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
IANDFCOA_00620 7.76e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
IANDFCOA_00621 8.95e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
IANDFCOA_00622 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IANDFCOA_00623 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IANDFCOA_00624 6.51e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IANDFCOA_00625 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IANDFCOA_00626 1.83e-169 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
IANDFCOA_00627 4.94e-214 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
IANDFCOA_00628 8.45e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IANDFCOA_00629 6.49e-269 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
IANDFCOA_00630 4.89e-202 ydhU - - P ko:K07217 - ko00000 Catalase
IANDFCOA_00633 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IANDFCOA_00636 1.9e-231 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IANDFCOA_00637 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
IANDFCOA_00638 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
IANDFCOA_00639 2.34e-107 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IANDFCOA_00640 5.46e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IANDFCOA_00641 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
IANDFCOA_00642 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IANDFCOA_00643 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IANDFCOA_00644 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IANDFCOA_00645 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IANDFCOA_00646 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
IANDFCOA_00647 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
IANDFCOA_00648 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IANDFCOA_00649 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IANDFCOA_00651 1.93e-53 - - - - - - - -
IANDFCOA_00652 7.05e-293 - - - S - - - Bacterial EndoU nuclease
IANDFCOA_00655 4.31e-82 yozB - - S ko:K08976 - ko00000 Membrane
IANDFCOA_00656 8.95e-31 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
IANDFCOA_00657 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
IANDFCOA_00658 4.32e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
IANDFCOA_00659 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
IANDFCOA_00660 7.03e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
IANDFCOA_00661 1.08e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
IANDFCOA_00662 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IANDFCOA_00663 1.61e-176 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
IANDFCOA_00664 1.79e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
IANDFCOA_00665 1.37e-248 - - - S - - - Ion transport 2 domain protein
IANDFCOA_00666 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IANDFCOA_00667 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
IANDFCOA_00668 1.79e-84 ydjM - - M - - - Lytic transglycolase
IANDFCOA_00669 9.38e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
IANDFCOA_00671 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
IANDFCOA_00672 4.9e-200 - - - I - - - Alpha/beta hydrolase family
IANDFCOA_00673 7.65e-226 yeaA - - S - - - Protein of unknown function (DUF4003)
IANDFCOA_00674 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
IANDFCOA_00675 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IANDFCOA_00676 1.02e-197 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IANDFCOA_00677 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
IANDFCOA_00678 1.59e-285 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IANDFCOA_00679 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
IANDFCOA_00680 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
IANDFCOA_00681 2.81e-282 pbuG - - S ko:K06901 - ko00000,ko02000 permease
IANDFCOA_00682 2.78e-163 yebC - - M - - - Membrane
IANDFCOA_00684 2.66e-120 yebE - - S - - - UPF0316 protein
IANDFCOA_00685 3.13e-38 yebG - - S - - - NETI protein
IANDFCOA_00686 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IANDFCOA_00687 4.83e-274 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IANDFCOA_00688 1.98e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IANDFCOA_00689 7.13e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
IANDFCOA_00690 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IANDFCOA_00691 6.66e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IANDFCOA_00692 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IANDFCOA_00693 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IANDFCOA_00694 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
IANDFCOA_00695 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IANDFCOA_00696 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
IANDFCOA_00697 5.69e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
IANDFCOA_00698 1.29e-94 - - - K - - - helix_turn_helix ASNC type
IANDFCOA_00699 4.8e-291 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
IANDFCOA_00700 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
IANDFCOA_00701 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
IANDFCOA_00702 9.18e-242 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
IANDFCOA_00703 7.62e-68 yerC - - S - - - protein conserved in bacteria
IANDFCOA_00704 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
IANDFCOA_00706 9.04e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IANDFCOA_00707 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
IANDFCOA_00708 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IANDFCOA_00709 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
IANDFCOA_00710 2.45e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
IANDFCOA_00711 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
IANDFCOA_00712 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IANDFCOA_00713 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IANDFCOA_00714 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IANDFCOA_00715 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IANDFCOA_00716 2.08e-190 yerO - - K - - - Transcriptional regulator
IANDFCOA_00717 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IANDFCOA_00718 5.16e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IANDFCOA_00719 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IANDFCOA_00721 9.11e-124 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IANDFCOA_00723 1.89e-51 - - - S - - - Immunity protein 22
IANDFCOA_00724 1.55e-230 - - - S - - - Bacterial EndoU nuclease
IANDFCOA_00725 2.48e-230 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
IANDFCOA_00726 1.94e-268 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
IANDFCOA_00728 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
IANDFCOA_00730 2.85e-129 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_00731 2.02e-106 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
IANDFCOA_00732 4.99e-195 yesF - - GM - - - NAD(P)H-binding
IANDFCOA_00733 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
IANDFCOA_00734 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
IANDFCOA_00735 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
IANDFCOA_00736 2.4e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
IANDFCOA_00737 1.95e-132 yesL - - S - - - Protein of unknown function, DUF624
IANDFCOA_00738 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_00739 1.89e-255 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
IANDFCOA_00740 6.85e-313 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
IANDFCOA_00741 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IANDFCOA_00742 5.11e-210 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IANDFCOA_00743 5.63e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
IANDFCOA_00744 0.0 yesS - - K - - - Transcriptional regulator
IANDFCOA_00745 9.8e-169 - - - E - - - GDSL-like Lipase/Acylhydrolase
IANDFCOA_00746 7.22e-163 yesU - - S - - - Domain of unknown function (DUF1961)
IANDFCOA_00747 7.78e-143 - - - S - - - Protein of unknown function, DUF624
IANDFCOA_00748 1.28e-200 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
IANDFCOA_00749 1.75e-221 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
IANDFCOA_00750 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
IANDFCOA_00751 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
IANDFCOA_00752 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
IANDFCOA_00753 0.0 yetA - - - - - - -
IANDFCOA_00754 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IANDFCOA_00755 6.84e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
IANDFCOA_00756 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IANDFCOA_00757 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
IANDFCOA_00758 1.49e-156 yetF - - S - - - membrane
IANDFCOA_00759 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
IANDFCOA_00760 7.08e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IANDFCOA_00761 9.79e-45 - - - - - - - -
IANDFCOA_00762 3.08e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IANDFCOA_00763 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
IANDFCOA_00764 2.1e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
IANDFCOA_00765 2.75e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
IANDFCOA_00766 1.78e-265 yetM - - CH - - - FAD binding domain
IANDFCOA_00767 2.57e-171 - - - M - - - Membrane
IANDFCOA_00768 4.11e-251 yetN - - S - - - Protein of unknown function (DUF3900)
IANDFCOA_00769 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IANDFCOA_00770 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IANDFCOA_00771 2.41e-187 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
IANDFCOA_00772 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
IANDFCOA_00773 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
IANDFCOA_00774 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
IANDFCOA_00775 2.84e-244 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
IANDFCOA_00776 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IANDFCOA_00777 9.43e-171 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IANDFCOA_00778 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
IANDFCOA_00779 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IANDFCOA_00780 5.14e-161 yfmS - - NT - - - chemotaxis protein
IANDFCOA_00781 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IANDFCOA_00782 6.48e-99 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
IANDFCOA_00783 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
IANDFCOA_00784 2.07e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
IANDFCOA_00785 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IANDFCOA_00786 1.2e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
IANDFCOA_00787 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
IANDFCOA_00788 6.98e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
IANDFCOA_00789 1.72e-268 - - - G - - - Major Facilitator Superfamily
IANDFCOA_00790 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
IANDFCOA_00791 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
IANDFCOA_00792 4.94e-222 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IANDFCOA_00793 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IANDFCOA_00794 3.22e-218 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IANDFCOA_00795 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
IANDFCOA_00796 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
IANDFCOA_00797 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
IANDFCOA_00798 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
IANDFCOA_00799 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IANDFCOA_00800 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
IANDFCOA_00801 1.45e-232 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
IANDFCOA_00803 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IANDFCOA_00804 6.92e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IANDFCOA_00805 4.6e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IANDFCOA_00806 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
IANDFCOA_00807 5.91e-158 yflK - - S - - - protein conserved in bacteria
IANDFCOA_00808 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
IANDFCOA_00809 9.81e-27 yflI - - - - - - -
IANDFCOA_00810 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
IANDFCOA_00811 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IANDFCOA_00812 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IANDFCOA_00813 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IANDFCOA_00814 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
IANDFCOA_00815 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
IANDFCOA_00816 2.19e-249 yfkT - - E ko:K06309 - ko00000 Spore germination protein
IANDFCOA_00818 5.37e-270 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
IANDFCOA_00819 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
IANDFCOA_00820 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IANDFCOA_00821 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
IANDFCOA_00822 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
IANDFCOA_00823 5.27e-161 frp - - C - - - nitroreductase
IANDFCOA_00824 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IANDFCOA_00825 5.48e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IANDFCOA_00826 2.07e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IANDFCOA_00827 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
IANDFCOA_00828 9.78e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IANDFCOA_00829 1.03e-66 yfkI - - S - - - gas vesicle protein
IANDFCOA_00830 7.92e-183 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
IANDFCOA_00831 1.64e-12 - - - - - - - -
IANDFCOA_00832 2.7e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IANDFCOA_00833 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
IANDFCOA_00834 3.69e-189 yfkD - - S - - - YfkD-like protein
IANDFCOA_00835 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
IANDFCOA_00836 7.17e-283 yfkA - - S - - - YfkB-like domain
IANDFCOA_00837 3.26e-36 yfjT - - - - - - -
IANDFCOA_00838 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
IANDFCOA_00839 5.16e-189 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IANDFCOA_00840 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
IANDFCOA_00841 2.76e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IANDFCOA_00842 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IANDFCOA_00843 3.04e-59 - - - S - - - YfzA-like protein
IANDFCOA_00844 3.47e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IANDFCOA_00845 9.55e-111 yfjM - - S - - - Psort location Cytoplasmic, score
IANDFCOA_00846 9.2e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IANDFCOA_00847 2.64e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IANDFCOA_00848 2.7e-261 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IANDFCOA_00849 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IANDFCOA_00850 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
IANDFCOA_00851 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
IANDFCOA_00852 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
IANDFCOA_00853 1.9e-109 - - - S - - - Family of unknown function (DUF5381)
IANDFCOA_00854 3.83e-161 yfjC - - - - - - -
IANDFCOA_00855 6.91e-241 yfjB - - - - - - -
IANDFCOA_00856 1.6e-60 yfjA - - S - - - Belongs to the WXG100 family
IANDFCOA_00857 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IANDFCOA_00858 2.05e-179 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
IANDFCOA_00859 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IANDFCOA_00860 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
IANDFCOA_00861 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
IANDFCOA_00862 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IANDFCOA_00863 3.34e-83 yfiD3 - - S - - - DoxX
IANDFCOA_00864 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
IANDFCOA_00866 1.98e-271 baeS - - T - - - Histidine kinase
IANDFCOA_00867 6.07e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
IANDFCOA_00868 7.89e-217 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_00869 1.46e-264 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IANDFCOA_00870 3.84e-259 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IANDFCOA_00871 1.89e-128 padR - - K - - - transcriptional
IANDFCOA_00872 3.2e-127 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
IANDFCOA_00873 5.4e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IANDFCOA_00874 9.81e-129 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
IANDFCOA_00875 0.0 yfiU - - EGP - - - the major facilitator superfamily
IANDFCOA_00876 2.11e-103 yfiV - - K - - - transcriptional
IANDFCOA_00877 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IANDFCOA_00878 1.56e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IANDFCOA_00879 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IANDFCOA_00880 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IANDFCOA_00881 7.61e-215 yfhB - - S - - - PhzF family
IANDFCOA_00882 2.87e-138 yfhC - - C - - - nitroreductase
IANDFCOA_00883 8.86e-35 yfhD - - S - - - YfhD-like protein
IANDFCOA_00885 3.11e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
IANDFCOA_00886 9.32e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
IANDFCOA_00887 4.8e-67 yfhH - - S - - - Protein of unknown function (DUF1811)
IANDFCOA_00888 3.47e-268 yfhI - - EGP - - - -transporter
IANDFCOA_00889 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
IANDFCOA_00890 8.95e-60 yfhJ - - S - - - WVELL protein
IANDFCOA_00891 1.7e-117 yfhK - - T - - - Bacterial SH3 domain homologues
IANDFCOA_00892 4.74e-62 yfhL - - S - - - SdpI/YhfL protein family
IANDFCOA_00893 3.93e-218 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
IANDFCOA_00894 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IANDFCOA_00895 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
IANDFCOA_00896 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
IANDFCOA_00897 8.47e-268 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
IANDFCOA_00898 1.73e-48 yfhS - - - - - - -
IANDFCOA_00899 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IANDFCOA_00900 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
IANDFCOA_00901 2.01e-49 ygaB - - S - - - YgaB-like protein
IANDFCOA_00902 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
IANDFCOA_00903 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
IANDFCOA_00904 1.87e-238 ygaE - - S - - - Membrane
IANDFCOA_00905 1.97e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IANDFCOA_00906 1.19e-112 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
IANDFCOA_00907 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
IANDFCOA_00908 5.46e-74 ygzB - - S - - - UPF0295 protein
IANDFCOA_00909 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
IANDFCOA_00910 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IANDFCOA_00927 6.37e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
IANDFCOA_00928 3.88e-37 - - - - - - - -
IANDFCOA_00929 6.95e-173 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
IANDFCOA_00930 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IANDFCOA_00931 0.0 ygaK - - C - - - Berberine and berberine like
IANDFCOA_00933 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IANDFCOA_00934 9.01e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IANDFCOA_00935 8.45e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
IANDFCOA_00936 4.82e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IANDFCOA_00937 2.2e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
IANDFCOA_00939 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IANDFCOA_00940 2.79e-102 ygaO - - - - - - -
IANDFCOA_00941 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_00943 1.92e-147 yhzB - - S - - - B3/4 domain
IANDFCOA_00944 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IANDFCOA_00945 1.32e-223 yhbB - - S - - - Putative amidase domain
IANDFCOA_00946 5.37e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IANDFCOA_00947 1.38e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
IANDFCOA_00948 2.66e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IANDFCOA_00949 4.06e-103 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IANDFCOA_00950 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
IANDFCOA_00951 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
IANDFCOA_00952 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
IANDFCOA_00953 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
IANDFCOA_00954 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
IANDFCOA_00955 9.84e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
IANDFCOA_00956 3.95e-59 yhcC - - - - - - -
IANDFCOA_00957 1.03e-69 - - - - - - - -
IANDFCOA_00958 4.78e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_00959 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_00960 1.85e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_00961 2.32e-210 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IANDFCOA_00962 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
IANDFCOA_00963 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
IANDFCOA_00964 7.08e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
IANDFCOA_00965 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IANDFCOA_00966 1.13e-70 yhcM - - - - - - -
IANDFCOA_00967 1.74e-107 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IANDFCOA_00968 6.03e-222 yhcP - - - - - - -
IANDFCOA_00969 1.68e-146 yhcQ - - M - - - Spore coat protein
IANDFCOA_00970 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IANDFCOA_00971 7.24e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
IANDFCOA_00972 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IANDFCOA_00973 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
IANDFCOA_00974 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
IANDFCOA_00975 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
IANDFCOA_00976 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IANDFCOA_00977 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IANDFCOA_00978 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IANDFCOA_00979 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IANDFCOA_00980 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IANDFCOA_00981 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IANDFCOA_00982 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
IANDFCOA_00983 7.33e-270 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_00984 7.42e-142 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IANDFCOA_00985 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
IANDFCOA_00986 1.65e-51 yhdB - - S - - - YhdB-like protein
IANDFCOA_00987 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
IANDFCOA_00988 1.2e-268 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IANDFCOA_00989 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
IANDFCOA_00990 1.51e-306 ygxB - - M - - - Conserved TM helix
IANDFCOA_00991 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
IANDFCOA_00992 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
IANDFCOA_00993 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IANDFCOA_00994 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_00995 1.45e-258 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IANDFCOA_00996 1.58e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IANDFCOA_00997 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
IANDFCOA_00998 2.48e-309 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IANDFCOA_00999 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IANDFCOA_01000 2.05e-99 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IANDFCOA_01001 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
IANDFCOA_01002 3.54e-257 yhdL - - S - - - Sigma factor regulator N-terminal
IANDFCOA_01003 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IANDFCOA_01004 1.93e-243 yhdN - - C - - - Aldo keto reductase
IANDFCOA_01005 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IANDFCOA_01006 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IANDFCOA_01007 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
IANDFCOA_01008 2.08e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IANDFCOA_01009 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
IANDFCOA_01010 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IANDFCOA_01011 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IANDFCOA_01012 5.44e-174 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IANDFCOA_01013 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
IANDFCOA_01014 4.51e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
IANDFCOA_01015 2.93e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IANDFCOA_01016 5.7e-200 nodB1 - - G - - - deacetylase
IANDFCOA_01017 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IANDFCOA_01018 3.77e-305 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IANDFCOA_01019 3.85e-109 nhaX - - T - - - Belongs to the universal stress protein A family
IANDFCOA_01020 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IANDFCOA_01021 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IANDFCOA_01022 3.31e-143 yheG - - GM - - - NAD(P)H-binding
IANDFCOA_01023 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
IANDFCOA_01024 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
IANDFCOA_01025 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
IANDFCOA_01026 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
IANDFCOA_01027 1.69e-258 yheB - - S - - - Belongs to the UPF0754 family
IANDFCOA_01028 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
IANDFCOA_01029 2.24e-262 yhaZ - - L - - - DNA alkylation repair enzyme
IANDFCOA_01030 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
IANDFCOA_01031 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
IANDFCOA_01032 7.54e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
IANDFCOA_01033 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IANDFCOA_01035 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
IANDFCOA_01036 2.29e-36 - - - S - - - YhzD-like protein
IANDFCOA_01037 1.31e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_01038 5.99e-271 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
IANDFCOA_01039 2.22e-299 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
IANDFCOA_01040 0.0 yhaN - - L - - - AAA domain
IANDFCOA_01041 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
IANDFCOA_01042 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
IANDFCOA_01043 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IANDFCOA_01044 1.4e-116 yhaK - - S - - - Putative zincin peptidase
IANDFCOA_01045 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
IANDFCOA_01046 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
IANDFCOA_01047 1.74e-54 yhaH - - S - - - YtxH-like protein
IANDFCOA_01048 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
IANDFCOA_01049 2.51e-260 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IANDFCOA_01050 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IANDFCOA_01051 7.73e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
IANDFCOA_01052 1.27e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
IANDFCOA_01053 1.01e-161 ecsC - - S - - - EcsC protein family
IANDFCOA_01054 6.01e-289 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IANDFCOA_01055 2.31e-313 yhfA - - C - - - membrane
IANDFCOA_01056 1.23e-45 - - - C - - - Rubrerythrin
IANDFCOA_01057 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
IANDFCOA_01058 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IANDFCOA_01059 1.76e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IANDFCOA_01060 5.66e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
IANDFCOA_01061 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IANDFCOA_01062 1e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_01063 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
IANDFCOA_01064 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IANDFCOA_01065 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
IANDFCOA_01066 2.68e-253 yhfE - - G - - - peptidase M42
IANDFCOA_01067 6.22e-93 - - - S - - - ASCH
IANDFCOA_01068 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IANDFCOA_01069 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IANDFCOA_01070 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
IANDFCOA_01071 1.01e-141 yhfK - - GM - - - NmrA-like family
IANDFCOA_01072 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IANDFCOA_01073 5.6e-85 yhfM - - - - - - -
IANDFCOA_01074 9.64e-308 yhfN - - O - - - Peptidase M48
IANDFCOA_01075 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IANDFCOA_01076 8.5e-100 - - - K - - - acetyltransferase
IANDFCOA_01077 1.39e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
IANDFCOA_01078 2.27e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IANDFCOA_01079 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
IANDFCOA_01080 7.05e-249 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IANDFCOA_01081 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IANDFCOA_01082 1.21e-117 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
IANDFCOA_01083 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
IANDFCOA_01084 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
IANDFCOA_01085 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IANDFCOA_01086 9.84e-45 yhzC - - S - - - IDEAL
IANDFCOA_01087 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
IANDFCOA_01088 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IANDFCOA_01089 5e-57 yhjA - - S - - - Excalibur calcium-binding domain
IANDFCOA_01090 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IANDFCOA_01091 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
IANDFCOA_01092 2.57e-78 yhjD - - - - - - -
IANDFCOA_01093 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
IANDFCOA_01094 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IANDFCOA_01095 0.0 yhjG - - CH - - - FAD binding domain
IANDFCOA_01096 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
IANDFCOA_01097 2.46e-270 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
IANDFCOA_01098 7.71e-255 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IANDFCOA_01099 2.63e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
IANDFCOA_01100 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
IANDFCOA_01101 1.07e-239 yhjM - - K - - - Transcriptional regulator
IANDFCOA_01102 1.02e-258 yhjN - - S ko:K07120 - ko00000 membrane
IANDFCOA_01103 4.25e-271 - - - EGP - - - Transmembrane secretion effector
IANDFCOA_01104 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
IANDFCOA_01105 2.19e-100 yhjR - - S - - - Rubrerythrin
IANDFCOA_01106 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
IANDFCOA_01107 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
IANDFCOA_01108 1.63e-279 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IANDFCOA_01109 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
IANDFCOA_01110 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
IANDFCOA_01111 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
IANDFCOA_01112 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
IANDFCOA_01113 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
IANDFCOA_01114 1e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
IANDFCOA_01115 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
IANDFCOA_01116 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
IANDFCOA_01117 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
IANDFCOA_01118 8.94e-221 cotH - - M ko:K06330 - ko00000 Spore Coat
IANDFCOA_01119 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IANDFCOA_01120 1.02e-74 yisL - - S - - - UPF0344 protein
IANDFCOA_01121 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IANDFCOA_01122 7.42e-132 yisN - - S - - - Protein of unknown function (DUF2777)
IANDFCOA_01123 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IANDFCOA_01124 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
IANDFCOA_01125 1.54e-189 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
IANDFCOA_01126 1.01e-310 yisQ - - V - - - Mate efflux family protein
IANDFCOA_01127 4.04e-207 yisR - - K - - - Transcriptional regulator
IANDFCOA_01128 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IANDFCOA_01129 5.17e-249 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IANDFCOA_01130 9.94e-120 yisT - - S - - - DinB family
IANDFCOA_01131 5.96e-128 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
IANDFCOA_01132 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IANDFCOA_01133 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
IANDFCOA_01134 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IANDFCOA_01135 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
IANDFCOA_01136 1.6e-294 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
IANDFCOA_01137 2.15e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
IANDFCOA_01138 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
IANDFCOA_01139 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
IANDFCOA_01140 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IANDFCOA_01141 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IANDFCOA_01142 1.01e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IANDFCOA_01143 1.4e-200 yitH - - K - - - Acetyltransferase (GNAT) domain
IANDFCOA_01144 5.09e-92 - - - S - - - Acetyltransferase (GNAT) domain
IANDFCOA_01145 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IANDFCOA_01146 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
IANDFCOA_01147 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
IANDFCOA_01148 4.16e-122 - - - - - - - -
IANDFCOA_01149 1.42e-218 - - - - - - - -
IANDFCOA_01150 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
IANDFCOA_01151 1.2e-76 - - - K - - - Transcriptional regulator PadR-like family
IANDFCOA_01152 6.11e-120 - - - - - - - -
IANDFCOA_01153 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
IANDFCOA_01154 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
IANDFCOA_01155 9.13e-202 yitS - - S - - - protein conserved in bacteria
IANDFCOA_01156 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IANDFCOA_01157 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
IANDFCOA_01158 4.11e-25 - - - S - - - Protein of unknown function (DUF3813)
IANDFCOA_01159 1.92e-08 - - - - - - - -
IANDFCOA_01160 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IANDFCOA_01161 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IANDFCOA_01162 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
IANDFCOA_01163 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
IANDFCOA_01164 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
IANDFCOA_01165 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
IANDFCOA_01166 7.41e-255 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IANDFCOA_01167 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IANDFCOA_01168 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
IANDFCOA_01169 3.98e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
IANDFCOA_01170 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IANDFCOA_01171 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
IANDFCOA_01172 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IANDFCOA_01173 2.94e-38 yjzC - - S - - - YjzC-like protein
IANDFCOA_01174 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
IANDFCOA_01175 9.84e-182 yjaU - - I - - - carboxylic ester hydrolase activity
IANDFCOA_01176 5.41e-134 yjaV - - - - - - -
IANDFCOA_01177 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
IANDFCOA_01178 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
IANDFCOA_01179 2.67e-38 yjzB - - - - - - -
IANDFCOA_01180 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IANDFCOA_01181 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IANDFCOA_01182 9.48e-193 yjaZ - - O - - - Zn-dependent protease
IANDFCOA_01183 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IANDFCOA_01184 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IANDFCOA_01185 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
IANDFCOA_01186 3.73e-213 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IANDFCOA_01187 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IANDFCOA_01188 7.51e-189 yjbA - - S - - - Belongs to the UPF0736 family
IANDFCOA_01189 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
IANDFCOA_01190 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IANDFCOA_01191 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IANDFCOA_01192 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IANDFCOA_01193 3.92e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IANDFCOA_01194 3.12e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IANDFCOA_01195 9.6e-260 yjbB - - EGP - - - Major Facilitator Superfamily
IANDFCOA_01196 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IANDFCOA_01197 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IANDFCOA_01198 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
IANDFCOA_01199 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IANDFCOA_01200 4.38e-282 coiA - - S ko:K06198 - ko00000 Competence protein
IANDFCOA_01201 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
IANDFCOA_01202 2.68e-28 - - - - - - - -
IANDFCOA_01204 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IANDFCOA_01205 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
IANDFCOA_01206 7.22e-129 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IANDFCOA_01207 4.94e-128 yjbK - - S - - - protein conserved in bacteria
IANDFCOA_01208 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
IANDFCOA_01209 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
IANDFCOA_01210 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IANDFCOA_01211 9.01e-204 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IANDFCOA_01212 6.5e-162 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IANDFCOA_01213 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IANDFCOA_01214 1.11e-174 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IANDFCOA_01215 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
IANDFCOA_01216 1.42e-271 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
IANDFCOA_01217 1.8e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
IANDFCOA_01218 2.76e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IANDFCOA_01219 6.18e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IANDFCOA_01220 3.98e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IANDFCOA_01221 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
IANDFCOA_01222 3.11e-98 yjbX - - S - - - Spore coat protein
IANDFCOA_01223 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
IANDFCOA_01224 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
IANDFCOA_01225 1.23e-95 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
IANDFCOA_01226 9.3e-32 cotW - - - ko:K06341 - ko00000 -
IANDFCOA_01227 2.34e-66 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
IANDFCOA_01228 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
IANDFCOA_01231 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
IANDFCOA_01232 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IANDFCOA_01233 6.31e-51 - - - - - - - -
IANDFCOA_01234 1.1e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IANDFCOA_01235 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
IANDFCOA_01236 1.91e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
IANDFCOA_01237 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IANDFCOA_01238 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IANDFCOA_01239 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
IANDFCOA_01240 1.05e-273 yjcL - - S - - - Protein of unknown function (DUF819)
IANDFCOA_01243 1.33e-50 - - - - - - - -
IANDFCOA_01245 1.66e-295 - - - M - - - nucleic acid phosphodiester bond hydrolysis
IANDFCOA_01248 1.42e-09 - - - S - - - YolD-like protein
IANDFCOA_01249 1.92e-47 - - - - - - - -
IANDFCOA_01250 3.94e-26 - - - - - - - -
IANDFCOA_01251 2.49e-07 - - - - - - - -
IANDFCOA_01252 5.19e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
IANDFCOA_01253 9.79e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
IANDFCOA_01254 0.000759 - - - - - - - -
IANDFCOA_01255 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
IANDFCOA_01256 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IANDFCOA_01257 5.95e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IANDFCOA_01258 4.58e-76 yjdF3 - - S - - - Protein of unknown function (DUF2992)
IANDFCOA_01259 2.44e-115 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IANDFCOA_01261 1.12e-101 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IANDFCOA_01262 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
IANDFCOA_01263 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
IANDFCOA_01264 5.31e-224 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IANDFCOA_01266 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
IANDFCOA_01267 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
IANDFCOA_01268 1.95e-30 yjfB - - S - - - Putative motility protein
IANDFCOA_01269 7.02e-214 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
IANDFCOA_01270 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
IANDFCOA_01271 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
IANDFCOA_01272 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
IANDFCOA_01273 2.27e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
IANDFCOA_01275 3.7e-147 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
IANDFCOA_01277 1.25e-281 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IANDFCOA_01278 4.84e-277 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IANDFCOA_01279 1.11e-41 - - - - - - - -
IANDFCOA_01280 4.82e-186 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IANDFCOA_01281 1.82e-155 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
IANDFCOA_01282 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IANDFCOA_01283 3.12e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
IANDFCOA_01284 1e-117 yjlB - - S - - - Cupin domain
IANDFCOA_01285 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
IANDFCOA_01286 3.56e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IANDFCOA_01287 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
IANDFCOA_01288 4.34e-314 - - - G ko:K03292 - ko00000 symporter YjmB
IANDFCOA_01289 2.08e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
IANDFCOA_01290 9.24e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
IANDFCOA_01291 3.92e-273 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
IANDFCOA_01292 5.47e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IANDFCOA_01293 9.24e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
IANDFCOA_01294 9.87e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
IANDFCOA_01295 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
IANDFCOA_01296 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
IANDFCOA_01297 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
IANDFCOA_01298 2.71e-103 yjoA - - S - - - DinB family
IANDFCOA_01299 1.67e-311 VCP - - O - - - AAA domain (dynein-related subfamily)
IANDFCOA_01300 3.5e-271 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IANDFCOA_01302 1.79e-55 - - - S - - - YCII-related domain
IANDFCOA_01303 5.12e-216 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IANDFCOA_01304 1.35e-80 yjqA - - S - - - Bacterial PH domain
IANDFCOA_01305 3.73e-137 yjqB - - S - - - Pfam:DUF867
IANDFCOA_01306 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
IANDFCOA_01307 1.79e-143 xkdA - - E - - - IrrE N-terminal-like domain
IANDFCOA_01308 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
IANDFCOA_01310 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
IANDFCOA_01311 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
IANDFCOA_01315 9.88e-111 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IANDFCOA_01316 7.93e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
IANDFCOA_01317 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
IANDFCOA_01318 0.0 yqbA - - S - - - portal protein
IANDFCOA_01319 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
IANDFCOA_01320 3.91e-217 xkdG - - S - - - Phage capsid family
IANDFCOA_01321 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
IANDFCOA_01322 1.5e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
IANDFCOA_01323 8.3e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
IANDFCOA_01324 2.87e-101 xkdJ - - - - - - -
IANDFCOA_01325 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
IANDFCOA_01326 6.01e-99 xkdM - - S - - - Phage tail tube protein
IANDFCOA_01327 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
IANDFCOA_01328 0.0 xkdO - - L - - - Transglycosylase SLT domain
IANDFCOA_01329 4.25e-152 xkdP - - S - - - Lysin motif
IANDFCOA_01330 1.56e-230 xkdQ - - G - - - NLP P60 protein
IANDFCOA_01331 5.05e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
IANDFCOA_01332 1.1e-89 xkdS - - S - - - Protein of unknown function (DUF2634)
IANDFCOA_01333 1.47e-242 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IANDFCOA_01334 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
IANDFCOA_01335 4.43e-56 - - - - - - - -
IANDFCOA_01336 1.87e-219 - - - - - - - -
IANDFCOA_01337 1.28e-59 xkdW - - S - - - XkdW protein
IANDFCOA_01338 6.35e-31 xkdX - - - - - - -
IANDFCOA_01339 2.21e-193 xepA - - - - - - -
IANDFCOA_01340 4.47e-51 xhlA - - S - - - Haemolysin XhlA
IANDFCOA_01341 1.15e-52 xhlB - - S - - - SPP1 phage holin
IANDFCOA_01342 5.3e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
IANDFCOA_01344 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
IANDFCOA_01345 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
IANDFCOA_01346 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
IANDFCOA_01347 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
IANDFCOA_01348 8.98e-310 steT - - E ko:K03294 - ko00000 amino acid
IANDFCOA_01349 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IANDFCOA_01350 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IANDFCOA_01351 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IANDFCOA_01353 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IANDFCOA_01354 1.16e-178 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
IANDFCOA_01355 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
IANDFCOA_01356 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IANDFCOA_01357 9.02e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IANDFCOA_01358 1.35e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IANDFCOA_01359 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IANDFCOA_01361 4.26e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
IANDFCOA_01362 1.24e-259 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IANDFCOA_01363 2.56e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IANDFCOA_01364 1.77e-238 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IANDFCOA_01365 9.83e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
IANDFCOA_01366 4.37e-206 ykgA - - E - - - Amidinotransferase
IANDFCOA_01367 3.82e-120 ykhA - - I - - - Acyl-CoA hydrolase
IANDFCOA_01368 2.65e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IANDFCOA_01369 5.85e-13 - - - - - - - -
IANDFCOA_01370 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
IANDFCOA_01371 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
IANDFCOA_01372 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IANDFCOA_01373 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
IANDFCOA_01374 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
IANDFCOA_01375 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IANDFCOA_01376 3.16e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IANDFCOA_01377 3.38e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IANDFCOA_01379 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
IANDFCOA_01380 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
IANDFCOA_01381 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
IANDFCOA_01382 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
IANDFCOA_01383 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IANDFCOA_01384 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IANDFCOA_01385 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IANDFCOA_01386 3.65e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
IANDFCOA_01387 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_01388 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
IANDFCOA_01389 2.34e-140 ykoF - - S - - - YKOF-related Family
IANDFCOA_01390 3.03e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IANDFCOA_01391 3.13e-309 ykoH - - T - - - Histidine kinase
IANDFCOA_01392 2.26e-144 ykoI - - S - - - Peptidase propeptide and YPEB domain
IANDFCOA_01393 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
IANDFCOA_01394 1.45e-08 - - - - - - - -
IANDFCOA_01396 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
IANDFCOA_01397 1.49e-70 tnrA - - K - - - transcriptional
IANDFCOA_01398 1.63e-25 - - - - - - - -
IANDFCOA_01399 3.04e-36 ykoL - - - - - - -
IANDFCOA_01400 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
IANDFCOA_01401 6.37e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
IANDFCOA_01402 1.44e-128 ykoP - - G - - - polysaccharide deacetylase
IANDFCOA_01403 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
IANDFCOA_01404 0.0 ykoS - - - - - - -
IANDFCOA_01405 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
IANDFCOA_01406 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
IANDFCOA_01407 1.25e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IANDFCOA_01408 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
IANDFCOA_01409 1.71e-143 ykoX - - S - - - membrane-associated protein
IANDFCOA_01410 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IANDFCOA_01411 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IANDFCOA_01412 1.63e-212 rsgI - - S - - - Anti-sigma factor N-terminus
IANDFCOA_01413 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
IANDFCOA_01414 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
IANDFCOA_01415 9.33e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
IANDFCOA_01416 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
IANDFCOA_01418 1.77e-28 ykzE - - - - - - -
IANDFCOA_01419 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
IANDFCOA_01420 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_01421 1.53e-112 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IANDFCOA_01423 1.33e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IANDFCOA_01424 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IANDFCOA_01425 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IANDFCOA_01426 2.67e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IANDFCOA_01427 2.29e-293 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IANDFCOA_01428 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IANDFCOA_01429 1.84e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IANDFCOA_01430 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IANDFCOA_01431 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
IANDFCOA_01433 5.62e-93 eag - - - - - - -
IANDFCOA_01434 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IANDFCOA_01435 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
IANDFCOA_01436 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IANDFCOA_01437 2.01e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IANDFCOA_01438 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
IANDFCOA_01439 2.36e-227 ykvI - - S - - - membrane
IANDFCOA_01440 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IANDFCOA_01441 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
IANDFCOA_01442 2.06e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IANDFCOA_01443 1.37e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IANDFCOA_01444 2.8e-81 ykvN - - K - - - Transcriptional regulator
IANDFCOA_01445 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IANDFCOA_01446 1.82e-273 - - - M - - - Glycosyl transferases group 1
IANDFCOA_01447 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
IANDFCOA_01448 1.75e-204 - - - G - - - Glycosyl hydrolases family 18
IANDFCOA_01449 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
IANDFCOA_01450 5.43e-35 ykvS - - S - - - protein conserved in bacteria
IANDFCOA_01451 2.5e-39 - - - - - - - -
IANDFCOA_01452 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
IANDFCOA_01453 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IANDFCOA_01454 1.31e-113 stoA - - CO - - - thiol-disulfide
IANDFCOA_01455 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IANDFCOA_01456 3.99e-09 - - - - - - - -
IANDFCOA_01457 1.93e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IANDFCOA_01458 6.34e-228 ykvZ - - K - - - Transcriptional regulator
IANDFCOA_01460 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
IANDFCOA_01461 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IANDFCOA_01462 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
IANDFCOA_01463 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IANDFCOA_01464 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_01465 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
IANDFCOA_01466 1.06e-167 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IANDFCOA_01467 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IANDFCOA_01468 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IANDFCOA_01469 2.97e-169 ykwD - - J - - - protein with SCP PR1 domains
IANDFCOA_01470 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IANDFCOA_01471 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_01472 3.44e-282 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IANDFCOA_01473 1.05e-22 - - - - - - - -
IANDFCOA_01474 2.02e-215 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
IANDFCOA_01475 3.71e-110 ykyB - - S - - - YkyB-like protein
IANDFCOA_01476 2.97e-304 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IANDFCOA_01477 5.84e-115 ykuD - - S - - - protein conserved in bacteria
IANDFCOA_01478 2.45e-210 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
IANDFCOA_01479 2.91e-179 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IANDFCOA_01480 2.05e-297 ykuI - - T - - - Diguanylate phosphodiesterase
IANDFCOA_01481 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
IANDFCOA_01482 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
IANDFCOA_01483 7.83e-38 ykzF - - S - - - Antirepressor AbbA
IANDFCOA_01484 5.15e-100 ykuL - - S - - - CBS domain
IANDFCOA_01485 6.52e-216 ccpC - - K - - - Transcriptional regulator
IANDFCOA_01486 8.34e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
IANDFCOA_01487 7.7e-226 ykuO - - - - - - -
IANDFCOA_01488 6.2e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
IANDFCOA_01489 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IANDFCOA_01490 7.66e-274 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IANDFCOA_01491 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
IANDFCOA_01492 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
IANDFCOA_01493 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
IANDFCOA_01494 1.47e-104 ykuV - - CO - - - thiol-disulfide
IANDFCOA_01495 4.71e-122 rok - - K - - - Repressor of ComK
IANDFCOA_01496 4.03e-199 yknT - - - ko:K06437 - ko00000 -
IANDFCOA_01497 3.75e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IANDFCOA_01498 1.26e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IANDFCOA_01499 2.38e-310 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
IANDFCOA_01500 4.89e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
IANDFCOA_01501 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
IANDFCOA_01502 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IANDFCOA_01503 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IANDFCOA_01504 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IANDFCOA_01505 5.34e-150 yknW - - S - - - Yip1 domain
IANDFCOA_01506 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IANDFCOA_01507 1.44e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_01508 1.92e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IANDFCOA_01509 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_01510 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
IANDFCOA_01511 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IANDFCOA_01512 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IANDFCOA_01513 5.43e-52 ykoA - - - - - - -
IANDFCOA_01514 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IANDFCOA_01515 2.86e-215 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IANDFCOA_01516 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
IANDFCOA_01517 1.09e-18 - - - S - - - Uncharacterized protein YkpC
IANDFCOA_01518 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
IANDFCOA_01519 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
IANDFCOA_01520 2.65e-306 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IANDFCOA_01521 8.06e-197 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
IANDFCOA_01522 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IANDFCOA_01523 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IANDFCOA_01524 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IANDFCOA_01525 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
IANDFCOA_01526 4.79e-186 ykrA - - S - - - hydrolases of the HAD superfamily
IANDFCOA_01527 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IANDFCOA_01528 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IANDFCOA_01529 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
IANDFCOA_01530 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IANDFCOA_01531 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IANDFCOA_01532 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IANDFCOA_01533 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IANDFCOA_01534 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
IANDFCOA_01535 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
IANDFCOA_01536 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
IANDFCOA_01537 1.45e-149 yktB - - S - - - Belongs to the UPF0637 family
IANDFCOA_01538 4.48e-35 ykzI - - - - - - -
IANDFCOA_01539 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
IANDFCOA_01540 2.98e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
IANDFCOA_01541 2.88e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IANDFCOA_01542 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
IANDFCOA_01543 0.0 ylaA - - - - - - -
IANDFCOA_01544 1.44e-56 ylaB - - - - - - -
IANDFCOA_01545 1.45e-114 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IANDFCOA_01547 1.74e-57 ylaE - - - - - - -
IANDFCOA_01548 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
IANDFCOA_01549 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
IANDFCOA_01550 4.4e-63 ylaH - - S - - - YlaH-like protein
IANDFCOA_01551 8.92e-44 ylaI - - S - - - protein conserved in bacteria
IANDFCOA_01552 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IANDFCOA_01553 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
IANDFCOA_01554 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IANDFCOA_01555 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IANDFCOA_01556 5.71e-58 ylaN - - S - - - Belongs to the UPF0358 family
IANDFCOA_01557 2.87e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IANDFCOA_01558 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IANDFCOA_01559 1.65e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IANDFCOA_01560 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IANDFCOA_01561 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IANDFCOA_01562 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IANDFCOA_01563 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IANDFCOA_01564 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IANDFCOA_01565 1.04e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
IANDFCOA_01566 1.61e-81 ylbA - - S - - - YugN-like family
IANDFCOA_01567 3.09e-97 ylbB - - T - - - COG0517 FOG CBS domain
IANDFCOA_01568 1.53e-256 ylbC - - S - - - protein with SCP PR1 domains
IANDFCOA_01569 3.24e-89 ylbD - - S - - - Putative coat protein
IANDFCOA_01570 1.73e-48 ylbE - - S - - - YlbE-like protein
IANDFCOA_01571 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
IANDFCOA_01572 8.8e-52 ylbG - - S - - - UPF0298 protein
IANDFCOA_01573 1.74e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
IANDFCOA_01574 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IANDFCOA_01575 1.58e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
IANDFCOA_01576 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IANDFCOA_01577 3.18e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
IANDFCOA_01578 1.05e-294 ylbM - - S - - - Belongs to the UPF0348 family
IANDFCOA_01580 1.99e-116 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
IANDFCOA_01581 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
IANDFCOA_01582 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IANDFCOA_01583 1.33e-115 ylbP - - K - - - n-acetyltransferase
IANDFCOA_01584 9.62e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IANDFCOA_01585 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IANDFCOA_01586 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
IANDFCOA_01587 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IANDFCOA_01588 3.42e-68 ftsL - - D - - - Essential cell division protein
IANDFCOA_01589 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IANDFCOA_01590 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
IANDFCOA_01591 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IANDFCOA_01592 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IANDFCOA_01593 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IANDFCOA_01594 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IANDFCOA_01595 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IANDFCOA_01596 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
IANDFCOA_01597 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IANDFCOA_01598 2.23e-142 ylxW - - S - - - protein conserved in bacteria
IANDFCOA_01599 1.06e-132 ylxX - - S - - - protein conserved in bacteria
IANDFCOA_01600 5.37e-76 sbp - - S - - - small basic protein
IANDFCOA_01601 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IANDFCOA_01602 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IANDFCOA_01603 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
IANDFCOA_01604 5.03e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IANDFCOA_01605 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IANDFCOA_01606 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IANDFCOA_01607 3.84e-189 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IANDFCOA_01608 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
IANDFCOA_01609 3.58e-51 ylmC - - S - - - sporulation protein
IANDFCOA_01610 3.07e-202 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
IANDFCOA_01611 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IANDFCOA_01612 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IANDFCOA_01613 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
IANDFCOA_01614 5e-177 ylmH - - S - - - conserved protein, contains S4-like domain
IANDFCOA_01615 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
IANDFCOA_01616 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IANDFCOA_01617 1.58e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
IANDFCOA_01618 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IANDFCOA_01619 5.85e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IANDFCOA_01620 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IANDFCOA_01621 2.5e-292 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
IANDFCOA_01622 3.46e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
IANDFCOA_01623 9.71e-317 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IANDFCOA_01624 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IANDFCOA_01625 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
IANDFCOA_01626 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IANDFCOA_01627 1.22e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IANDFCOA_01628 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IANDFCOA_01629 1.27e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IANDFCOA_01631 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
IANDFCOA_01632 6.01e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
IANDFCOA_01633 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
IANDFCOA_01634 3.76e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
IANDFCOA_01635 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IANDFCOA_01636 1.45e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
IANDFCOA_01637 1.08e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
IANDFCOA_01638 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
IANDFCOA_01639 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
IANDFCOA_01640 8.41e-202 yloC - - S - - - stress-induced protein
IANDFCOA_01641 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
IANDFCOA_01642 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
IANDFCOA_01643 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IANDFCOA_01644 7.28e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IANDFCOA_01645 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IANDFCOA_01646 8.3e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IANDFCOA_01647 1.28e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IANDFCOA_01648 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IANDFCOA_01649 5.3e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IANDFCOA_01650 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
IANDFCOA_01651 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
IANDFCOA_01652 3.92e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IANDFCOA_01653 1.1e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
IANDFCOA_01654 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
IANDFCOA_01655 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
IANDFCOA_01656 3.65e-78 yloU - - S - - - protein conserved in bacteria
IANDFCOA_01657 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
IANDFCOA_01658 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IANDFCOA_01659 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IANDFCOA_01660 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IANDFCOA_01661 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IANDFCOA_01662 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IANDFCOA_01663 1.79e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IANDFCOA_01664 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IANDFCOA_01665 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IANDFCOA_01666 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IANDFCOA_01667 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
IANDFCOA_01668 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IANDFCOA_01669 1.67e-114 - - - - - - - -
IANDFCOA_01670 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IANDFCOA_01671 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IANDFCOA_01672 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
IANDFCOA_01673 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
IANDFCOA_01674 3.41e-80 ylqD - - S - - - YlqD protein
IANDFCOA_01675 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IANDFCOA_01676 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
IANDFCOA_01677 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IANDFCOA_01678 4.89e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IANDFCOA_01679 2.89e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IANDFCOA_01680 0.0 ylqG - - - - - - -
IANDFCOA_01681 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
IANDFCOA_01682 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IANDFCOA_01683 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IANDFCOA_01684 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
IANDFCOA_01685 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IANDFCOA_01686 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IANDFCOA_01687 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
IANDFCOA_01688 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IANDFCOA_01689 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IANDFCOA_01690 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IANDFCOA_01691 3.27e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IANDFCOA_01692 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
IANDFCOA_01693 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
IANDFCOA_01694 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
IANDFCOA_01695 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IANDFCOA_01696 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
IANDFCOA_01697 1.22e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IANDFCOA_01698 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
IANDFCOA_01699 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
IANDFCOA_01700 1.28e-311 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
IANDFCOA_01701 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
IANDFCOA_01702 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
IANDFCOA_01703 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
IANDFCOA_01704 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IANDFCOA_01705 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IANDFCOA_01706 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
IANDFCOA_01707 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
IANDFCOA_01708 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
IANDFCOA_01709 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
IANDFCOA_01710 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
IANDFCOA_01711 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IANDFCOA_01712 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IANDFCOA_01713 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
IANDFCOA_01714 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
IANDFCOA_01715 2.58e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IANDFCOA_01716 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
IANDFCOA_01717 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
IANDFCOA_01718 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IANDFCOA_01719 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IANDFCOA_01720 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IANDFCOA_01721 6.62e-99 ylxL - - - - - - -
IANDFCOA_01722 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
IANDFCOA_01723 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IANDFCOA_01724 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
IANDFCOA_01725 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IANDFCOA_01726 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IANDFCOA_01727 1.36e-177 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
IANDFCOA_01728 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IANDFCOA_01729 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
IANDFCOA_01730 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IANDFCOA_01731 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IANDFCOA_01732 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
IANDFCOA_01733 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
IANDFCOA_01734 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
IANDFCOA_01735 6.16e-63 ylxQ - - J - - - ribosomal protein
IANDFCOA_01736 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IANDFCOA_01737 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
IANDFCOA_01738 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IANDFCOA_01739 1.17e-217 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IANDFCOA_01740 3.84e-231 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
IANDFCOA_01741 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IANDFCOA_01742 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IANDFCOA_01743 3.98e-230 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
IANDFCOA_01744 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
IANDFCOA_01745 1.53e-56 ymxH - - S - - - YlmC YmxH family
IANDFCOA_01746 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
IANDFCOA_01747 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IANDFCOA_01748 4.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IANDFCOA_01749 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IANDFCOA_01750 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IANDFCOA_01751 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IANDFCOA_01752 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
IANDFCOA_01753 4.94e-44 - - - S - - - YlzJ-like protein
IANDFCOA_01754 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IANDFCOA_01755 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_01756 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IANDFCOA_01757 1.35e-298 albE - - S - - - Peptidase M16
IANDFCOA_01758 6.8e-309 ymfH - - S - - - zinc protease
IANDFCOA_01759 1.49e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IANDFCOA_01760 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
IANDFCOA_01761 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
IANDFCOA_01762 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
IANDFCOA_01763 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IANDFCOA_01764 4.33e-299 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
IANDFCOA_01765 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IANDFCOA_01766 2.82e-280 pbpX - - V - - - Beta-lactamase
IANDFCOA_01767 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
IANDFCOA_01768 5.08e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
IANDFCOA_01769 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
IANDFCOA_01770 7.12e-254 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IANDFCOA_01771 2.4e-277 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IANDFCOA_01772 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IANDFCOA_01773 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
IANDFCOA_01774 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
IANDFCOA_01775 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IANDFCOA_01776 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IANDFCOA_01777 2.93e-92 - - - S - - - Regulatory protein YrvL
IANDFCOA_01779 1.13e-126 ymcC - - S - - - Membrane
IANDFCOA_01780 3.43e-140 pksA - - K - - - Transcriptional regulator
IANDFCOA_01781 9.47e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
IANDFCOA_01782 1.78e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IANDFCOA_01784 1.64e-236 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
IANDFCOA_01785 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IANDFCOA_01786 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
IANDFCOA_01787 5.31e-304 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IANDFCOA_01788 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
IANDFCOA_01789 2.04e-183 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
IANDFCOA_01790 1.75e-173 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
IANDFCOA_01791 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IANDFCOA_01792 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IANDFCOA_01793 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IANDFCOA_01794 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IANDFCOA_01795 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
IANDFCOA_01796 9.72e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IANDFCOA_01797 9.39e-80 ymzB - - - - - - -
IANDFCOA_01798 7.65e-207 - - - S - - - Metallo-beta-lactamase superfamily
IANDFCOA_01799 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
IANDFCOA_01801 3.96e-163 ymaC - - S - - - Replication protein
IANDFCOA_01802 8.49e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
IANDFCOA_01803 6.39e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
IANDFCOA_01804 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IANDFCOA_01806 5.41e-76 ymaF - - S - - - YmaF family
IANDFCOA_01807 3.95e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IANDFCOA_01808 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IANDFCOA_01809 1.63e-31 - - - - - - - -
IANDFCOA_01810 1.2e-30 ymzA - - - - - - -
IANDFCOA_01811 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
IANDFCOA_01812 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IANDFCOA_01813 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IANDFCOA_01814 2.24e-141 - - - - - - - -
IANDFCOA_01815 2e-150 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IANDFCOA_01816 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
IANDFCOA_01817 2.12e-292 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IANDFCOA_01818 1.95e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IANDFCOA_01819 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
IANDFCOA_01820 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
IANDFCOA_01821 3.24e-173 - - - L - - - Belongs to the 'phage' integrase family
IANDFCOA_01824 4.77e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
IANDFCOA_01825 1.2e-07 - - - K - - - Helix-turn-helix domain
IANDFCOA_01830 3.88e-93 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
IANDFCOA_01831 1.48e-21 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
IANDFCOA_01837 2.78e-08 - - - - - - - -
IANDFCOA_01841 8.49e-111 - - - V - - - restriction endodeoxyribonuclease activity
IANDFCOA_01843 3.59e-66 - - - M - - - ArpU family transcriptional regulator
IANDFCOA_01844 1.2e-77 - - - L - - - Phage integrase family
IANDFCOA_01847 4.85e-53 - - - S - - - SEC-C motif
IANDFCOA_01848 4.65e-64 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
IANDFCOA_01849 6.85e-103 - - - L - - - phage terminase small subunit
IANDFCOA_01850 1.04e-42 - - - S - - - Terminase
IANDFCOA_01853 4.18e-14 - - - - - - - -
IANDFCOA_01855 8.39e-80 - - - Q - - - Collagen triple helix repeat (20 copies)
IANDFCOA_01856 2.26e-118 - - - M - - - Glycosyltransferase like family
IANDFCOA_01857 7.89e-154 - - - H - - - Methionine biosynthesis protein MetW
IANDFCOA_01858 1.03e-240 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
IANDFCOA_01859 1.56e-274 - - - H - - - N-terminal domain of galactosyltransferase
IANDFCOA_01861 3.38e-125 ynaD - - J - - - Acetyltransferase (GNAT) domain
IANDFCOA_01863 3.45e-90 - - - S - - - CAAX protease self-immunity
IANDFCOA_01864 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IANDFCOA_01865 2.79e-30 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
IANDFCOA_01866 1.52e-156 - - - S - - - Domain of unknown function (DUF3885)
IANDFCOA_01867 1.06e-80 ynaF - - - - - - -
IANDFCOA_01869 4.32e-110 - - - E - - - phosphoribosylanthranilate isomerase activity
IANDFCOA_01870 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
IANDFCOA_01871 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IANDFCOA_01872 5.85e-274 xylR - - GK - - - ROK family
IANDFCOA_01873 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
IANDFCOA_01874 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
IANDFCOA_01875 2.06e-144 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
IANDFCOA_01876 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IANDFCOA_01877 5.06e-280 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IANDFCOA_01878 3.86e-107 - - - S - - - Protein of unknown function (DUF2691)
IANDFCOA_01879 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
IANDFCOA_01880 7.54e-22 - - - - - - - -
IANDFCOA_01883 2.75e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IANDFCOA_01885 4.44e-172 - - - S - - - Domain of unknown function, YrpD
IANDFCOA_01888 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
IANDFCOA_01889 8.92e-96 - - - - - - - -
IANDFCOA_01890 1.05e-102 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
IANDFCOA_01893 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IANDFCOA_01894 1.95e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
IANDFCOA_01895 5.57e-289 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
IANDFCOA_01896 1.85e-198 yndG - - S - - - DoxX-like family
IANDFCOA_01897 3.46e-149 - - - S - - - Domain of unknown function (DUF4166)
IANDFCOA_01898 0.0 yndJ - - S - - - YndJ-like protein
IANDFCOA_01900 3.26e-175 yndL - - S - - - Replication protein
IANDFCOA_01901 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
IANDFCOA_01902 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IANDFCOA_01903 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IANDFCOA_01904 2.44e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IANDFCOA_01905 2.29e-144 yneB - - L - - - resolvase
IANDFCOA_01906 1.15e-43 ynzC - - S - - - UPF0291 protein
IANDFCOA_01907 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IANDFCOA_01908 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
IANDFCOA_01909 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
IANDFCOA_01910 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
IANDFCOA_01911 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
IANDFCOA_01912 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
IANDFCOA_01913 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
IANDFCOA_01914 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
IANDFCOA_01915 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
IANDFCOA_01916 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
IANDFCOA_01917 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
IANDFCOA_01918 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IANDFCOA_01919 2.53e-118 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IANDFCOA_01920 9.26e-10 - - - S - - - Fur-regulated basic protein B
IANDFCOA_01922 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
IANDFCOA_01923 1.64e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
IANDFCOA_01924 2.32e-71 yneQ - - - - - - -
IANDFCOA_01925 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
IANDFCOA_01926 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IANDFCOA_01927 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
IANDFCOA_01928 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IANDFCOA_01929 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IANDFCOA_01930 1.82e-18 - - - - - - - -
IANDFCOA_01931 1.06e-75 ynfC - - - - - - -
IANDFCOA_01932 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IANDFCOA_01933 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
IANDFCOA_01935 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
IANDFCOA_01936 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IANDFCOA_01937 4.06e-102 yngA - - S - - - membrane
IANDFCOA_01938 7.53e-208 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IANDFCOA_01939 2.01e-134 yngC - - S - - - membrane-associated protein
IANDFCOA_01940 7.39e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
IANDFCOA_01941 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IANDFCOA_01942 1.42e-173 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
IANDFCOA_01943 3.89e-211 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
IANDFCOA_01944 1.19e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
IANDFCOA_01945 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
IANDFCOA_01946 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IANDFCOA_01947 7.28e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IANDFCOA_01948 2.97e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IANDFCOA_01949 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
IANDFCOA_01950 2.48e-83 yngL - - S - - - Protein of unknown function (DUF1360)
IANDFCOA_01951 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
IANDFCOA_01952 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IANDFCOA_01953 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IANDFCOA_01954 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IANDFCOA_01955 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IANDFCOA_01956 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IANDFCOA_01957 2.73e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
IANDFCOA_01958 9.8e-313 yoeA - - V - - - MATE efflux family protein
IANDFCOA_01959 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
IANDFCOA_01961 1.14e-124 - - - L - - - Integrase
IANDFCOA_01962 1.92e-46 yoeD - - G - - - Helix-turn-helix domain
IANDFCOA_01963 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IANDFCOA_01964 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_01965 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IANDFCOA_01966 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IANDFCOA_01967 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
IANDFCOA_01968 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_01969 1.91e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IANDFCOA_01970 2.24e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IANDFCOA_01971 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IANDFCOA_01972 7.3e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IANDFCOA_01973 9.05e-52 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
IANDFCOA_01974 5.51e-168 yoxB - - - - - - -
IANDFCOA_01975 3.26e-113 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IANDFCOA_01976 4.51e-300 yoaB - - EGP - - - the major facilitator superfamily
IANDFCOA_01977 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
IANDFCOA_01978 3.36e-234 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IANDFCOA_01979 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IANDFCOA_01980 7.24e-45 yoaF - - - - - - -
IANDFCOA_01983 1.46e-19 - - - - - - - -
IANDFCOA_01984 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
IANDFCOA_01985 4.38e-308 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
IANDFCOA_01986 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
IANDFCOA_01987 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
IANDFCOA_01988 1.79e-145 yoaK - - S - - - Membrane
IANDFCOA_01989 1.43e-252 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
IANDFCOA_01990 2.07e-170 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
IANDFCOA_01993 8.89e-293 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IANDFCOA_01995 3.86e-183 yoaP - - K - - - YoaP-like
IANDFCOA_01996 3.01e-87 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
IANDFCOA_01998 1.87e-113 - - - - - - - -
IANDFCOA_01999 1.04e-217 yoaR - - V - - - vancomycin resistance protein
IANDFCOA_02000 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
IANDFCOA_02001 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_02002 1.57e-188 yoaT - - S - - - Protein of unknown function (DUF817)
IANDFCOA_02003 1.11e-201 yoaU - - K - - - LysR substrate binding domain
IANDFCOA_02004 3.7e-201 yoaV - - EG - - - EamA-like transporter family
IANDFCOA_02005 1.89e-100 yoaW - - - - - - -
IANDFCOA_02006 5.94e-148 lin0465 - - S - - - DJ-1/PfpI family
IANDFCOA_02007 2.09e-214 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
IANDFCOA_02010 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
IANDFCOA_02011 1.07e-156 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
IANDFCOA_02012 1e-47 - - - S - - - TM2 domain
IANDFCOA_02013 7.63e-74 - - - K - - - Helix-turn-helix
IANDFCOA_02016 7.44e-66 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
IANDFCOA_02021 1.56e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IANDFCOA_02025 6.81e-66 - - - S - - - Tetratricopeptide repeat
IANDFCOA_02026 2.51e-74 - - - J - - - tRNA cytidylyltransferase activity
IANDFCOA_02034 8.49e-265 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IANDFCOA_02036 4.52e-201 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IANDFCOA_02037 2.36e-44 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IANDFCOA_02039 3.72e-58 - - - - - - - -
IANDFCOA_02041 5.21e-26 - - - - - - - -
IANDFCOA_02042 8.94e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IANDFCOA_02043 3.93e-117 yokH - - G - - - SMI1 / KNR4 family
IANDFCOA_02044 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
IANDFCOA_02045 1.75e-69 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
IANDFCOA_02046 1.18e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
IANDFCOA_02047 2.93e-180 - - - J - - - FR47-like protein
IANDFCOA_02048 3.09e-127 yobS - - K - - - Transcriptional regulator
IANDFCOA_02049 3.16e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IANDFCOA_02050 1.01e-110 - - - K - - - Bacterial transcription activator, effector binding domain
IANDFCOA_02051 2.3e-226 yobV - - K - - - WYL domain
IANDFCOA_02052 3.01e-120 yobW - - - - - - -
IANDFCOA_02053 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
IANDFCOA_02054 2.89e-151 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IANDFCOA_02055 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
IANDFCOA_02056 2.49e-183 - - - - - - - -
IANDFCOA_02057 1.08e-121 yocC - - - - - - -
IANDFCOA_02058 6.71e-241 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
IANDFCOA_02059 5.67e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
IANDFCOA_02060 3.51e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_02061 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IANDFCOA_02062 1.67e-174 yocH - - M - - - COG1388 FOG LysM repeat
IANDFCOA_02063 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IANDFCOA_02064 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IANDFCOA_02065 4.07e-107 yocK - - T - - - general stress protein
IANDFCOA_02066 3.02e-70 yocL - - - - - - -
IANDFCOA_02067 3.93e-41 - - - - - - - -
IANDFCOA_02068 2.21e-113 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IANDFCOA_02069 2.94e-55 yozN - - - - - - -
IANDFCOA_02070 1.83e-49 yocN - - - - - - -
IANDFCOA_02071 2.17e-74 yozO - - S - - - Bacterial PH domain
IANDFCOA_02072 1.91e-42 yozC - - - - - - -
IANDFCOA_02073 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IANDFCOA_02074 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
IANDFCOA_02075 3.91e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
IANDFCOA_02076 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IANDFCOA_02077 4.5e-212 yocS - - S ko:K03453 - ko00000 -transporter
IANDFCOA_02078 2.59e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IANDFCOA_02079 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IANDFCOA_02080 0.0 yojO - - P - - - Von Willebrand factor
IANDFCOA_02081 3.82e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
IANDFCOA_02082 7.31e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IANDFCOA_02083 7.5e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IANDFCOA_02084 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
IANDFCOA_02085 1.19e-138 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IANDFCOA_02087 2.06e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
IANDFCOA_02088 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IANDFCOA_02089 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
IANDFCOA_02090 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
IANDFCOA_02091 1.85e-58 - - - - - - - -
IANDFCOA_02092 1.92e-206 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
IANDFCOA_02093 4.26e-105 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
IANDFCOA_02094 1.95e-14 - - - - - - - -
IANDFCOA_02095 2.65e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
IANDFCOA_02096 3.97e-84 iolK - - S - - - tautomerase
IANDFCOA_02097 2.63e-73 yodB - - K - - - transcriptional
IANDFCOA_02098 1.92e-140 yodC - - C - - - nitroreductase
IANDFCOA_02099 3.76e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
IANDFCOA_02100 3.38e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IANDFCOA_02101 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
IANDFCOA_02102 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IANDFCOA_02103 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IANDFCOA_02104 6.12e-166 yodH - - Q - - - Methyltransferase
IANDFCOA_02105 2.93e-42 yodI - - - - - - -
IANDFCOA_02106 7.71e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
IANDFCOA_02107 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
IANDFCOA_02108 2.08e-12 - - - - - - - -
IANDFCOA_02109 1.17e-71 yodL - - S - - - YodL-like
IANDFCOA_02110 1.15e-137 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
IANDFCOA_02111 5.18e-34 yozD - - S - - - YozD-like protein
IANDFCOA_02113 1.29e-159 yodN - - - - - - -
IANDFCOA_02114 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
IANDFCOA_02115 1.4e-62 yokU - - S - - - YokU-like protein, putative antitoxin
IANDFCOA_02116 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
IANDFCOA_02117 1.84e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
IANDFCOA_02118 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
IANDFCOA_02119 2.71e-152 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IANDFCOA_02120 3.27e-159 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IANDFCOA_02121 2.34e-315 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IANDFCOA_02123 9.78e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
IANDFCOA_02124 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
IANDFCOA_02125 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
IANDFCOA_02126 1.12e-85 cgeA - - - ko:K06319 - ko00000 -
IANDFCOA_02127 4.7e-237 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
IANDFCOA_02128 2.31e-279 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
IANDFCOA_02129 1.61e-82 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IANDFCOA_02131 3.07e-129 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IANDFCOA_02134 2.22e-40 - - - S - - - Macro domain
IANDFCOA_02142 1.3e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
IANDFCOA_02145 3.73e-83 - - - - - - - -
IANDFCOA_02147 3.29e-39 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IANDFCOA_02148 8.84e-207 - - - S - - - Thymidylate synthase
IANDFCOA_02152 4.97e-96 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
IANDFCOA_02155 1.75e-66 - - - S - - - Peptidyl-tRNA hydrolase PTH2
IANDFCOA_02157 6.25e-47 - - - O - - - Glutaredoxin
IANDFCOA_02158 4.35e-125 - - - L - - - HNH endonuclease
IANDFCOA_02159 1.44e-135 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IANDFCOA_02161 2.36e-205 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IANDFCOA_02162 1.04e-259 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IANDFCOA_02163 2.3e-79 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
IANDFCOA_02169 2.6e-10 - - - S - - - Protein of unknown function (DUF1653)
IANDFCOA_02177 2.52e-26 - - - S - - - Calcineurin-like phosphoesterase
IANDFCOA_02184 1.82e-101 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
IANDFCOA_02186 2.63e-104 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
IANDFCOA_02191 1.81e-135 - - - S - - - protein conserved in bacteria
IANDFCOA_02192 0.0 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
IANDFCOA_02193 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
IANDFCOA_02194 1.91e-285 - - - L - - - DNA primase activity
IANDFCOA_02195 0.0 - - - J - - - DnaB-like helicase C terminal domain
IANDFCOA_02196 1.45e-108 - - - - - - - -
IANDFCOA_02197 4.28e-227 - - - L - - - AAA domain
IANDFCOA_02198 5.17e-198 - - - - - - - -
IANDFCOA_02202 0.0 - - - M - - - Parallel beta-helix repeats
IANDFCOA_02203 2.86e-180 - - - S - - - Pfam:DUF867
IANDFCOA_02205 3.28e-31 - - - S - - - YopX protein
IANDFCOA_02208 9.57e-35 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
IANDFCOA_02209 3.98e-104 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
IANDFCOA_02210 1.29e-190 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
IANDFCOA_02211 6.17e-103 - - - - - - - -
IANDFCOA_02217 5.25e-21 - - - - - - - -
IANDFCOA_02219 2.14e-89 yoqH - - M - - - LysM domain
IANDFCOA_02221 2.65e-15 - - - S - - - Protein of unknown function (DUF2815)
IANDFCOA_02222 6.12e-143 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
IANDFCOA_02228 2.24e-55 - - - - - - - -
IANDFCOA_02232 4.78e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_02233 8.29e-226 - - - - - - - -
IANDFCOA_02234 0.0 - - - S - - - DNA-sulfur modification-associated
IANDFCOA_02235 9.31e-251 - - - L - - - Belongs to the 'phage' integrase family
IANDFCOA_02240 2.46e-131 - - - - - - - -
IANDFCOA_02248 1.21e-37 - - - S - - - Protein of unknown function (DUF3102)
IANDFCOA_02254 7.55e-248 - - - L - - - Domain of unknown function (DUF4942)
IANDFCOA_02255 8.1e-06 - - - L - - - SNF2 family N-terminal domain
IANDFCOA_02256 3.66e-261 - - - - - - - -
IANDFCOA_02257 5.66e-121 - - - - - - - -
IANDFCOA_02260 0.0 - - - - - - - -
IANDFCOA_02261 2.02e-48 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IANDFCOA_02262 1.21e-257 - - - - - - - -
IANDFCOA_02265 5.08e-264 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
IANDFCOA_02268 1.55e-130 - - - - - - - -
IANDFCOA_02272 2.6e-86 - - - - - - - -
IANDFCOA_02275 7.77e-88 - - - - - - - -
IANDFCOA_02276 3.16e-102 - - - - - - - -
IANDFCOA_02277 1.09e-115 - - - - - - - -
IANDFCOA_02278 6.41e-75 - - - - - - - -
IANDFCOA_02281 1.9e-70 - - - - - - - -
IANDFCOA_02282 2.14e-35 - - - - - - - -
IANDFCOA_02285 1.12e-110 - - - - - - - -
IANDFCOA_02286 3.06e-89 - - - - - - - -
IANDFCOA_02287 4.75e-245 - - - A - - - Belongs to the 'phage' integrase family
IANDFCOA_02291 2.28e-149 - - - - - - - -
IANDFCOA_02292 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IANDFCOA_02293 7.98e-112 - - - S - - - Phage tail protein
IANDFCOA_02294 0.0 - - - S - - - Pfam Transposase IS66
IANDFCOA_02295 6.68e-143 - - - - - - - -
IANDFCOA_02296 2.12e-55 - - - S - - - virus tail, fiber
IANDFCOA_02297 6.99e-246 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
IANDFCOA_02299 4.83e-50 - - - S - - - Bacteriophage holin
IANDFCOA_02300 1.72e-244 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IANDFCOA_02302 1.02e-297 - - - S - - - damaged DNA binding
IANDFCOA_02303 1.44e-68 - - - S - - - YolD-like protein
IANDFCOA_02304 4.56e-74 - - - L - - - nuclease activity
IANDFCOA_02305 2.83e-104 - - - S - - - SMI1-KNR4 cell-wall
IANDFCOA_02306 1.78e-219 - - - S - - - Bacterial EndoU nuclease
IANDFCOA_02307 5.78e-167 - - - V - - - HNH endonuclease
IANDFCOA_02308 2.23e-86 - - - G - - - SMI1-KNR4 cell-wall
IANDFCOA_02309 9.4e-48 - - - - - - - -
IANDFCOA_02310 4.76e-167 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
IANDFCOA_02311 7.89e-105 - - - S ko:K03824 - ko00000,ko01000 family acetyltransferase
IANDFCOA_02312 4.61e-71 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IANDFCOA_02313 0.0 yokA - - L - - - Recombinase
IANDFCOA_02314 1.76e-124 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IANDFCOA_02315 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
IANDFCOA_02316 1.4e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IANDFCOA_02317 4.14e-94 ypoP - - K - - - transcriptional
IANDFCOA_02318 9.99e-290 mepA - - V - - - MATE efflux family protein
IANDFCOA_02319 2.13e-40 ypmT - - S - - - Uncharacterized ympT
IANDFCOA_02320 1.95e-128 ypmS - - S - - - protein conserved in bacteria
IANDFCOA_02321 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
IANDFCOA_02322 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IANDFCOA_02323 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
IANDFCOA_02324 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IANDFCOA_02325 1.4e-236 yplP - - K - - - Transcriptional regulator
IANDFCOA_02326 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
IANDFCOA_02327 1.71e-145 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IANDFCOA_02328 1.21e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IANDFCOA_02329 7.27e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IANDFCOA_02330 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
IANDFCOA_02331 3.47e-148 ypjP - - S - - - YpjP-like protein
IANDFCOA_02332 6.15e-187 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
IANDFCOA_02333 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
IANDFCOA_02334 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
IANDFCOA_02335 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
IANDFCOA_02336 3.3e-138 yagB - - S ko:K06950 - ko00000 phosphohydrolase
IANDFCOA_02337 3.13e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
IANDFCOA_02338 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IANDFCOA_02339 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IANDFCOA_02340 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
IANDFCOA_02341 1.17e-22 degR - - - - - - -
IANDFCOA_02342 5.22e-41 - - - S - - - Protein of unknown function (DUF2564)
IANDFCOA_02343 7.99e-41 ypeQ - - S - - - Zinc-finger
IANDFCOA_02344 6.45e-173 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
IANDFCOA_02345 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IANDFCOA_02346 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
IANDFCOA_02347 5.23e-05 - - - - ko:K06429 - ko00000 -
IANDFCOA_02348 2.26e-213 ypcP - - L - - - 5'3' exonuclease
IANDFCOA_02349 1.08e-11 - - - - - - - -
IANDFCOA_02350 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
IANDFCOA_02351 0.0 ypbR - - S - - - Dynamin family
IANDFCOA_02352 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
IANDFCOA_02353 2.07e-262 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
IANDFCOA_02354 3.51e-291 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
IANDFCOA_02355 1.65e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IANDFCOA_02356 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IANDFCOA_02357 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
IANDFCOA_02358 1.47e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
IANDFCOA_02359 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
IANDFCOA_02360 4.51e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
IANDFCOA_02361 1.2e-202 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IANDFCOA_02362 1.88e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IANDFCOA_02363 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
IANDFCOA_02365 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
IANDFCOA_02366 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IANDFCOA_02367 9.4e-128 ypsA - - S - - - Belongs to the UPF0398 family
IANDFCOA_02368 9.82e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
IANDFCOA_02369 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IANDFCOA_02370 1.34e-112 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
IANDFCOA_02371 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IANDFCOA_02372 8.72e-68 yppG - - S - - - YppG-like protein
IANDFCOA_02373 2.27e-11 - - - S - - - YppF-like protein
IANDFCOA_02374 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
IANDFCOA_02377 1.03e-237 yppC - - S - - - Protein of unknown function (DUF2515)
IANDFCOA_02378 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IANDFCOA_02379 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IANDFCOA_02380 1.17e-120 ypoC - - - - - - -
IANDFCOA_02381 5.92e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IANDFCOA_02382 1.9e-164 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
IANDFCOA_02383 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
IANDFCOA_02384 1.07e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IANDFCOA_02385 2.27e-103 ypmB - - S - - - protein conserved in bacteria
IANDFCOA_02386 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
IANDFCOA_02387 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
IANDFCOA_02388 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IANDFCOA_02389 2.23e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IANDFCOA_02390 9.39e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IANDFCOA_02391 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IANDFCOA_02392 3.7e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IANDFCOA_02393 1.65e-265 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
IANDFCOA_02394 2.21e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
IANDFCOA_02395 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
IANDFCOA_02396 6.89e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IANDFCOA_02397 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
IANDFCOA_02398 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IANDFCOA_02399 6.84e-183 ypjB - - S - - - sporulation protein
IANDFCOA_02400 1.15e-125 ypjA - - S - - - membrane
IANDFCOA_02401 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
IANDFCOA_02402 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
IANDFCOA_02403 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
IANDFCOA_02404 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
IANDFCOA_02405 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
IANDFCOA_02406 8.74e-298 ypiA - - S - - - COG0457 FOG TPR repeat
IANDFCOA_02407 1.64e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IANDFCOA_02408 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
IANDFCOA_02409 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IANDFCOA_02410 5.43e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IANDFCOA_02411 3.12e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IANDFCOA_02412 5.25e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
IANDFCOA_02413 8.44e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
IANDFCOA_02414 2.48e-229 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IANDFCOA_02415 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IANDFCOA_02416 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IANDFCOA_02417 7.79e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IANDFCOA_02418 5.88e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IANDFCOA_02419 2.13e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
IANDFCOA_02420 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IANDFCOA_02421 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IANDFCOA_02422 3.84e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IANDFCOA_02423 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IANDFCOA_02424 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IANDFCOA_02425 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
IANDFCOA_02426 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IANDFCOA_02427 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IANDFCOA_02428 2.5e-175 yphF - - - - - - -
IANDFCOA_02429 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
IANDFCOA_02430 6.32e-231 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
IANDFCOA_02431 1.72e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
IANDFCOA_02432 5.91e-38 ypzH - - - - - - -
IANDFCOA_02433 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
IANDFCOA_02434 3.87e-134 yphA - - - - - - -
IANDFCOA_02435 5.6e-12 - - - S - - - YpzI-like protein
IANDFCOA_02436 1.1e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IANDFCOA_02437 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
IANDFCOA_02438 3.91e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
IANDFCOA_02439 2.48e-32 - - - S - - - Family of unknown function (DUF5359)
IANDFCOA_02440 8.95e-142 ypfA - - M - - - Flagellar protein YcgR
IANDFCOA_02441 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
IANDFCOA_02442 1.1e-204 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
IANDFCOA_02443 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
IANDFCOA_02444 6.04e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
IANDFCOA_02445 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IANDFCOA_02446 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IANDFCOA_02447 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
IANDFCOA_02448 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
IANDFCOA_02449 5.04e-148 ypbE - - M - - - Lysin motif
IANDFCOA_02450 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
IANDFCOA_02451 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IANDFCOA_02452 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
IANDFCOA_02453 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
IANDFCOA_02454 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IANDFCOA_02455 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IANDFCOA_02456 3.37e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IANDFCOA_02457 1.23e-253 rsiX - - - - - - -
IANDFCOA_02458 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IANDFCOA_02459 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_02460 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IANDFCOA_02461 1.34e-278 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IANDFCOA_02462 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
IANDFCOA_02463 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IANDFCOA_02464 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IANDFCOA_02465 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
IANDFCOA_02466 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
IANDFCOA_02467 1.37e-271 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IANDFCOA_02468 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
IANDFCOA_02469 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IANDFCOA_02470 4.45e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IANDFCOA_02471 3.43e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
IANDFCOA_02472 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IANDFCOA_02473 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IANDFCOA_02474 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IANDFCOA_02475 2.05e-146 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
IANDFCOA_02476 1.77e-261 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IANDFCOA_02477 2.96e-72 ypuD - - - - - - -
IANDFCOA_02478 4.99e-127 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IANDFCOA_02479 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
IANDFCOA_02480 1.61e-16 - - - S - - - SNARE associated Golgi protein
IANDFCOA_02482 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IANDFCOA_02483 2.67e-193 ypuA - - S - - - Secreted protein
IANDFCOA_02484 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IANDFCOA_02485 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
IANDFCOA_02486 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
IANDFCOA_02487 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
IANDFCOA_02488 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
IANDFCOA_02489 5.52e-101 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
IANDFCOA_02490 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
IANDFCOA_02491 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
IANDFCOA_02492 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IANDFCOA_02493 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IANDFCOA_02494 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
IANDFCOA_02495 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IANDFCOA_02496 8.04e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IANDFCOA_02497 2.77e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
IANDFCOA_02498 1.59e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
IANDFCOA_02499 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
IANDFCOA_02500 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
IANDFCOA_02501 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IANDFCOA_02502 3.73e-44 yqkK - - - - - - -
IANDFCOA_02503 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IANDFCOA_02504 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IANDFCOA_02505 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
IANDFCOA_02506 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
IANDFCOA_02507 3.18e-77 ansR - - K - - - Transcriptional regulator
IANDFCOA_02508 2.62e-283 yqxK - - L - - - DNA helicase
IANDFCOA_02509 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
IANDFCOA_02510 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
IANDFCOA_02511 2.65e-217 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
IANDFCOA_02512 1.78e-29 yqkE - - S - - - Protein of unknown function (DUF3886)
IANDFCOA_02513 7.12e-226 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IANDFCOA_02514 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
IANDFCOA_02515 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
IANDFCOA_02516 1.37e-249 yqkA - - K - - - GrpB protein
IANDFCOA_02517 5.51e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
IANDFCOA_02518 5.25e-111 yqjY - - K ko:K06977 - ko00000 acetyltransferase
IANDFCOA_02519 9.27e-66 yqiX - - S - - - YolD-like protein
IANDFCOA_02520 3.45e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IANDFCOA_02522 2.04e-289 yqjV - - G - - - Major Facilitator Superfamily
IANDFCOA_02524 7.43e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IANDFCOA_02525 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
IANDFCOA_02526 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
IANDFCOA_02527 1.62e-183 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IANDFCOA_02528 3.82e-228 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IANDFCOA_02529 1.13e-188 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IANDFCOA_02530 0.0 rocB - - E - - - arginine degradation protein
IANDFCOA_02531 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IANDFCOA_02532 1.29e-186 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IANDFCOA_02533 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IANDFCOA_02534 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IANDFCOA_02535 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IANDFCOA_02536 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IANDFCOA_02537 2.72e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IANDFCOA_02538 1.77e-32 yqzJ - - - - - - -
IANDFCOA_02539 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IANDFCOA_02540 8.77e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
IANDFCOA_02541 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
IANDFCOA_02542 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IANDFCOA_02543 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
IANDFCOA_02545 2.41e-128 yqjB - - S - - - protein conserved in bacteria
IANDFCOA_02546 1.55e-224 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
IANDFCOA_02547 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IANDFCOA_02548 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IANDFCOA_02549 6.81e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IANDFCOA_02550 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
IANDFCOA_02551 4.06e-212 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IANDFCOA_02552 5.97e-265 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IANDFCOA_02553 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
IANDFCOA_02554 2.65e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IANDFCOA_02555 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IANDFCOA_02556 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IANDFCOA_02557 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IANDFCOA_02558 3.96e-254 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
IANDFCOA_02559 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IANDFCOA_02560 8.64e-199 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
IANDFCOA_02561 0.0 bkdR - - KT - - - Transcriptional regulator
IANDFCOA_02562 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
IANDFCOA_02563 4.18e-207 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IANDFCOA_02564 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
IANDFCOA_02565 1.12e-265 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IANDFCOA_02566 1.93e-265 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
IANDFCOA_02567 2.41e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
IANDFCOA_02568 5.7e-281 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IANDFCOA_02569 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IANDFCOA_02570 2.7e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
IANDFCOA_02571 2.26e-37 - - - - - - - -
IANDFCOA_02572 8.07e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IANDFCOA_02574 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IANDFCOA_02575 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
IANDFCOA_02576 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
IANDFCOA_02577 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
IANDFCOA_02578 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
IANDFCOA_02579 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IANDFCOA_02580 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IANDFCOA_02581 3.81e-50 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IANDFCOA_02582 2.05e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IANDFCOA_02583 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IANDFCOA_02584 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IANDFCOA_02585 1.65e-88 yqhY - - S - - - protein conserved in bacteria
IANDFCOA_02586 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IANDFCOA_02587 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IANDFCOA_02588 4.04e-134 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
IANDFCOA_02589 2.43e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
IANDFCOA_02590 2.58e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
IANDFCOA_02591 1.8e-255 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
IANDFCOA_02592 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
IANDFCOA_02593 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
IANDFCOA_02594 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
IANDFCOA_02595 3.35e-216 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
IANDFCOA_02596 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
IANDFCOA_02597 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IANDFCOA_02598 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IANDFCOA_02599 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
IANDFCOA_02600 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
IANDFCOA_02601 6.02e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
IANDFCOA_02602 5.18e-81 yqhP - - - - - - -
IANDFCOA_02603 3.33e-208 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IANDFCOA_02604 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IANDFCOA_02605 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IANDFCOA_02606 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
IANDFCOA_02607 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IANDFCOA_02608 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IANDFCOA_02609 1.11e-260 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
IANDFCOA_02610 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IANDFCOA_02611 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
IANDFCOA_02612 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
IANDFCOA_02613 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
IANDFCOA_02614 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
IANDFCOA_02615 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
IANDFCOA_02616 8e-156 yqxM - - - ko:K19433 - ko00000 -
IANDFCOA_02617 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
IANDFCOA_02618 3.33e-35 yqzE - - S - - - YqzE-like protein
IANDFCOA_02619 3.24e-58 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
IANDFCOA_02620 9.65e-59 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
IANDFCOA_02621 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
IANDFCOA_02622 1.05e-88 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
IANDFCOA_02623 3.09e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
IANDFCOA_02624 2.14e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
IANDFCOA_02625 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IANDFCOA_02627 3.8e-06 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
IANDFCOA_02628 1.51e-233 yqxL - - P - - - Mg2 transporter protein
IANDFCOA_02629 2.86e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IANDFCOA_02630 7.14e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IANDFCOA_02632 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
IANDFCOA_02633 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
IANDFCOA_02634 3.2e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
IANDFCOA_02635 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
IANDFCOA_02636 7.34e-66 yqgV - - S - - - Thiamine-binding protein
IANDFCOA_02637 2.69e-256 yqgU - - - - - - -
IANDFCOA_02638 3.04e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
IANDFCOA_02639 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IANDFCOA_02640 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
IANDFCOA_02641 2.19e-44 yqgQ - - S - - - Protein conserved in bacteria
IANDFCOA_02642 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
IANDFCOA_02643 3.38e-14 yqgO - - - - - - -
IANDFCOA_02644 3.8e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IANDFCOA_02645 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IANDFCOA_02646 2.81e-257 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
IANDFCOA_02648 2.81e-67 yqzD - - - - - - -
IANDFCOA_02649 1.09e-93 yqzC - - S - - - YceG-like family
IANDFCOA_02650 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IANDFCOA_02651 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IANDFCOA_02652 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
IANDFCOA_02653 1.43e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
IANDFCOA_02654 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
IANDFCOA_02655 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
IANDFCOA_02656 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
IANDFCOA_02657 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
IANDFCOA_02658 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
IANDFCOA_02659 1.58e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
IANDFCOA_02660 1.64e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
IANDFCOA_02661 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IANDFCOA_02662 2.04e-81 yqfX - - S - - - membrane
IANDFCOA_02663 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
IANDFCOA_02664 2.47e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
IANDFCOA_02665 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IANDFCOA_02666 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
IANDFCOA_02667 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IANDFCOA_02668 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IANDFCOA_02669 4.89e-58 yqfQ - - S - - - YqfQ-like protein
IANDFCOA_02670 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IANDFCOA_02671 9.26e-270 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IANDFCOA_02672 2.41e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
IANDFCOA_02673 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IANDFCOA_02674 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IANDFCOA_02675 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IANDFCOA_02676 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
IANDFCOA_02677 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IANDFCOA_02678 3.29e-144 ccpN - - K - - - CBS domain
IANDFCOA_02679 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
IANDFCOA_02680 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
IANDFCOA_02681 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
IANDFCOA_02682 5.29e-27 - - - S - - - YqzL-like protein
IANDFCOA_02683 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IANDFCOA_02684 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IANDFCOA_02685 1.42e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
IANDFCOA_02686 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IANDFCOA_02687 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
IANDFCOA_02689 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
IANDFCOA_02690 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
IANDFCOA_02691 2.07e-60 yqfC - - S - - - sporulation protein YqfC
IANDFCOA_02692 3.13e-79 yqfB - - - - - - -
IANDFCOA_02693 8.78e-192 yqfA - - S - - - UPF0365 protein
IANDFCOA_02694 1.32e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
IANDFCOA_02695 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
IANDFCOA_02696 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
IANDFCOA_02697 1.4e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
IANDFCOA_02698 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
IANDFCOA_02699 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IANDFCOA_02700 9.34e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
IANDFCOA_02701 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IANDFCOA_02702 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
IANDFCOA_02703 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IANDFCOA_02704 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IANDFCOA_02705 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
IANDFCOA_02706 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IANDFCOA_02707 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
IANDFCOA_02708 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
IANDFCOA_02709 1.39e-257 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IANDFCOA_02710 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
IANDFCOA_02711 1.16e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
IANDFCOA_02712 2.36e-22 - - - S - - - YqzM-like protein
IANDFCOA_02713 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
IANDFCOA_02714 5.39e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
IANDFCOA_02715 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
IANDFCOA_02716 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IANDFCOA_02717 9.8e-179 yqeM - - Q - - - Methyltransferase
IANDFCOA_02718 9.76e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IANDFCOA_02719 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
IANDFCOA_02720 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IANDFCOA_02721 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
IANDFCOA_02722 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IANDFCOA_02723 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IANDFCOA_02724 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
IANDFCOA_02726 6.41e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
IANDFCOA_02727 4.44e-172 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
IANDFCOA_02728 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
IANDFCOA_02729 1.29e-23 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
IANDFCOA_02730 3e-169 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
IANDFCOA_02731 9.38e-171 - - - - - - - -
IANDFCOA_02732 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
IANDFCOA_02733 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IANDFCOA_02734 0.0 - - - L ko:K06400 - ko00000 Recombinase
IANDFCOA_02735 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
IANDFCOA_02736 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
IANDFCOA_02737 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IANDFCOA_02738 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
IANDFCOA_02739 2.08e-197 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
IANDFCOA_02740 1.37e-30 - - - S - - - YtkA-like
IANDFCOA_02741 9e-62 - - - S - - - PepSY-associated TM region
IANDFCOA_02742 1.69e-142 - - - S - - - PepSY-associated TM region
IANDFCOA_02743 3.16e-81 - - - K - - - BetI-type transcriptional repressor, C-terminal
IANDFCOA_02744 1.78e-175 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
IANDFCOA_02745 1.77e-61 - - - - - - - -
IANDFCOA_02746 1.51e-54 - - - S - - - Protein of unknown function (DUF3992)
IANDFCOA_02747 4.35e-53 - - - S - - - Spore coat protein Z
IANDFCOA_02748 8.68e-120 - - - S - - - Tetratricopeptide repeat
IANDFCOA_02751 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
IANDFCOA_02752 1.37e-135 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
IANDFCOA_02754 5.4e-80 - - - - - - - -
IANDFCOA_02756 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IANDFCOA_02757 8.36e-89 - - - S - - - Bacteriophage holin family
IANDFCOA_02758 2.45e-213 xepA - - - - - - -
IANDFCOA_02759 9.34e-33 - - - - - - - -
IANDFCOA_02760 1.01e-73 xkdW - - S - - - XkdW protein
IANDFCOA_02761 2.91e-283 - - - - - - - -
IANDFCOA_02762 3e-54 - - - - - - - -
IANDFCOA_02763 4.58e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
IANDFCOA_02764 1.31e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IANDFCOA_02765 1.14e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
IANDFCOA_02766 6.68e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
IANDFCOA_02767 1.02e-231 xkdQ - - G - - - NLP P60 protein
IANDFCOA_02768 6.56e-156 xkdP - - S - - - Lysin motif
IANDFCOA_02769 0.0 xkdO - - L - - - Transglycosylase SLT domain
IANDFCOA_02770 1.27e-89 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
IANDFCOA_02771 1.21e-98 xkdM - - S - - - Phage tail tube protein
IANDFCOA_02772 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
IANDFCOA_02773 4.2e-35 - - - - - - - -
IANDFCOA_02774 8.94e-100 yqbJ - - - - - - -
IANDFCOA_02775 7.57e-114 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
IANDFCOA_02776 2.38e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
IANDFCOA_02777 2.89e-87 - - - S - - - Protein of unknown function (DUF3199)
IANDFCOA_02778 5.19e-61 - - - S - - - YqbF, hypothetical protein domain
IANDFCOA_02779 4.37e-214 xkdG - - S - - - Phage capsid family
IANDFCOA_02780 3.46e-157 yqbD - - L - - - Putative phage serine protease XkdF
IANDFCOA_02782 1.37e-182 - - - S - - - Phage Mu protein F like protein
IANDFCOA_02783 0.0 yqbA - - S - - - portal protein
IANDFCOA_02784 3.86e-316 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
IANDFCOA_02785 5.44e-147 yqaS - - L - - - DNA packaging
IANDFCOA_02788 1.71e-100 yqaQ - - L - - - Transposase
IANDFCOA_02791 1.24e-41 yqaO - - S - - - Phage-like element PBSX protein XtrA
IANDFCOA_02792 5.21e-93 rusA - - L - - - Endodeoxyribonuclease RusA
IANDFCOA_02794 2.72e-211 yqaM - - L - - - IstB-like ATP binding protein
IANDFCOA_02795 8.41e-153 yqaL - - L - - - DnaD domain protein
IANDFCOA_02796 1.13e-191 recT - - L ko:K07455 - ko00000,ko03400 RecT family
IANDFCOA_02797 3.76e-219 yqaJ - - L - - - YqaJ-like viral recombinase domain
IANDFCOA_02801 1.04e-133 - - - - - - - -
IANDFCOA_02803 1.02e-24 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
IANDFCOA_02804 1.88e-42 - - - K - - - sequence-specific DNA binding
IANDFCOA_02806 4.16e-130 yqaC - - F - - - adenylate kinase activity
IANDFCOA_02807 2.62e-121 xkdA - - E - - - IrrE N-terminal-like domain
IANDFCOA_02808 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IANDFCOA_02809 7.32e-306 yrkQ - - T - - - Histidine kinase
IANDFCOA_02810 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
IANDFCOA_02811 2.16e-282 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
IANDFCOA_02812 6.33e-133 yrkN - - K - - - Acetyltransferase (GNAT) family
IANDFCOA_02813 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
IANDFCOA_02814 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
IANDFCOA_02815 1.52e-154 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
IANDFCOA_02816 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
IANDFCOA_02817 7.74e-259 yrkH - - P - - - Rhodanese Homology Domain
IANDFCOA_02818 2.14e-23 perX - - S - - - DsrE/DsrF-like family
IANDFCOA_02819 1.95e-127 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
IANDFCOA_02820 1.61e-107 yrkE - - O - - - DsrE/DsrF/DrsH-like family
IANDFCOA_02821 4.38e-52 yrkD - - S - - - protein conserved in bacteria
IANDFCOA_02822 2.21e-138 yrkC - - G - - - Cupin domain
IANDFCOA_02823 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
IANDFCOA_02824 7.59e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IANDFCOA_02825 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
IANDFCOA_02826 1.02e-297 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IANDFCOA_02827 2.45e-23 - - - S - - - YrzO-like protein
IANDFCOA_02828 7.28e-218 yrdR - - EG - - - EamA-like transporter family
IANDFCOA_02829 9.87e-204 - - - K - - - Transcriptional regulator
IANDFCOA_02830 6.09e-254 trkA - - P ko:K07222 - ko00000 Oxidoreductase
IANDFCOA_02831 2.05e-204 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
IANDFCOA_02832 1.75e-87 yodA - - S - - - tautomerase
IANDFCOA_02833 1.24e-205 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
IANDFCOA_02834 5.01e-41 - - - C - - - COG2041 Sulfite oxidase and related enzymes
IANDFCOA_02835 1.01e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IANDFCOA_02836 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
IANDFCOA_02837 9.34e-176 azlC - - E - - - AzlC protein
IANDFCOA_02838 4.13e-104 bkdR - - K - - - helix_turn_helix ASNC type
IANDFCOA_02839 1.76e-22 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
IANDFCOA_02840 5.86e-294 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IANDFCOA_02841 1.01e-128 yrdC - - Q - - - Isochorismatase family
IANDFCOA_02842 2.99e-71 - - - S - - - Protein of unknown function (DUF2568)
IANDFCOA_02843 1.17e-117 yrdA - - S - - - DinB family
IANDFCOA_02844 5.77e-210 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
IANDFCOA_02845 5.15e-247 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IANDFCOA_02846 1.39e-187 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IANDFCOA_02847 4.62e-160 yrpD - - S - - - Domain of unknown function, YrpD
IANDFCOA_02848 6.71e-128 - - - K ko:K05799 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
IANDFCOA_02850 4.11e-268 - - - P - - - Major Facilitator Superfamily
IANDFCOA_02851 6.21e-148 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IANDFCOA_02852 1.02e-192 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
IANDFCOA_02853 4.98e-172 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG3959 Transketolase, N-terminal subunit
IANDFCOA_02854 3.1e-126 - - - S - - - Flavin reductase like domain
IANDFCOA_02855 1.12e-156 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
IANDFCOA_02856 1.62e-63 - - - S - - - YjbR
IANDFCOA_02857 7.31e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IANDFCOA_02858 3.99e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IANDFCOA_02859 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
IANDFCOA_02860 2.16e-285 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IANDFCOA_02861 2.97e-210 yraN - - K - - - Transcriptional regulator
IANDFCOA_02862 1.71e-262 yraM - - S - - - PrpF protein
IANDFCOA_02863 9.5e-201 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IANDFCOA_02864 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IANDFCOA_02865 2.33e-194 - - - S - - - Alpha beta hydrolase
IANDFCOA_02866 6.61e-80 - - - T - - - sh3 domain protein
IANDFCOA_02867 2.92e-81 - - - T - - - sh3 domain protein
IANDFCOA_02869 5.45e-86 - - - E - - - Glyoxalase-like domain
IANDFCOA_02870 1.2e-49 yraG - - - ko:K06440 - ko00000 -
IANDFCOA_02871 9.61e-84 yraF - - M - - - Spore coat protein
IANDFCOA_02872 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IANDFCOA_02873 6.11e-36 yraE - - - ko:K06440 - ko00000 -
IANDFCOA_02874 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
IANDFCOA_02875 3.7e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
IANDFCOA_02876 3.95e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
IANDFCOA_02877 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IANDFCOA_02878 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IANDFCOA_02879 5.66e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
IANDFCOA_02880 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
IANDFCOA_02881 8.91e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
IANDFCOA_02882 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
IANDFCOA_02883 0.0 levR - - K - - - PTS system fructose IIA component
IANDFCOA_02884 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IANDFCOA_02885 5.63e-137 yrhP - - E - - - LysE type translocator
IANDFCOA_02886 1.98e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
IANDFCOA_02887 8.2e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IANDFCOA_02888 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
IANDFCOA_02889 0.0 oatA - - I - - - Acyltransferase family
IANDFCOA_02890 1.15e-70 oatA - - I - - - Acyltransferase family
IANDFCOA_02891 5.19e-60 yrhK - - S - - - YrhK-like protein
IANDFCOA_02892 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IANDFCOA_02893 1.12e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
IANDFCOA_02894 1.1e-126 yrhH - - Q - - - methyltransferase
IANDFCOA_02895 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
IANDFCOA_02897 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
IANDFCOA_02899 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
IANDFCOA_02900 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
IANDFCOA_02901 1.22e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
IANDFCOA_02902 1.99e-48 yrhC - - S - - - YrhC-like protein
IANDFCOA_02903 9.98e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IANDFCOA_02904 1.36e-215 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
IANDFCOA_02905 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IANDFCOA_02906 8.44e-154 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
IANDFCOA_02907 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
IANDFCOA_02908 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
IANDFCOA_02909 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
IANDFCOA_02910 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IANDFCOA_02911 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
IANDFCOA_02912 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
IANDFCOA_02913 7.67e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
IANDFCOA_02914 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
IANDFCOA_02915 7.19e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IANDFCOA_02916 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
IANDFCOA_02917 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IANDFCOA_02918 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
IANDFCOA_02919 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IANDFCOA_02920 8.81e-242 yrrI - - S - - - AI-2E family transporter
IANDFCOA_02921 1.89e-169 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IANDFCOA_02922 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IANDFCOA_02923 6.53e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IANDFCOA_02924 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IANDFCOA_02925 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
IANDFCOA_02926 8.4e-42 yrzR - - - - - - -
IANDFCOA_02927 3.39e-106 yrrD - - S - - - protein conserved in bacteria
IANDFCOA_02928 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IANDFCOA_02929 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
IANDFCOA_02930 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IANDFCOA_02931 1.87e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IANDFCOA_02932 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_02933 2.44e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IANDFCOA_02934 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IANDFCOA_02935 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IANDFCOA_02936 5.19e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
IANDFCOA_02938 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
IANDFCOA_02939 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IANDFCOA_02940 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IANDFCOA_02941 8.47e-117 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IANDFCOA_02942 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
IANDFCOA_02943 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
IANDFCOA_02944 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IANDFCOA_02945 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IANDFCOA_02946 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
IANDFCOA_02947 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IANDFCOA_02948 6.34e-147 yrbG - - S - - - membrane
IANDFCOA_02949 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
IANDFCOA_02950 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
IANDFCOA_02951 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IANDFCOA_02952 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IANDFCOA_02953 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
IANDFCOA_02954 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IANDFCOA_02955 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IANDFCOA_02956 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
IANDFCOA_02957 0.0 csbX - - EGP - - - the major facilitator superfamily
IANDFCOA_02958 7.93e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
IANDFCOA_02959 2.32e-152 yrzF - - T - - - serine threonine protein kinase
IANDFCOA_02961 2.55e-67 - - - S - - - Family of unknown function (DUF5412)
IANDFCOA_02962 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
IANDFCOA_02963 8.63e-165 yebC - - K - - - transcriptional regulatory protein
IANDFCOA_02964 2.08e-69 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IANDFCOA_02965 4.02e-216 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
IANDFCOA_02966 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IANDFCOA_02967 5.07e-202 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
IANDFCOA_02968 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
IANDFCOA_02969 3.35e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IANDFCOA_02970 3.39e-121 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
IANDFCOA_02971 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
IANDFCOA_02972 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
IANDFCOA_02973 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IANDFCOA_02974 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
IANDFCOA_02975 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
IANDFCOA_02976 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
IANDFCOA_02977 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
IANDFCOA_02978 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
IANDFCOA_02979 1.83e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IANDFCOA_02980 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
IANDFCOA_02981 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IANDFCOA_02982 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
IANDFCOA_02983 1.91e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
IANDFCOA_02984 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
IANDFCOA_02985 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
IANDFCOA_02986 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
IANDFCOA_02987 4.67e-215 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
IANDFCOA_02988 3.15e-109 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IANDFCOA_02989 5.8e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
IANDFCOA_02990 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IANDFCOA_02991 1.53e-35 - - - - - - - -
IANDFCOA_02992 2.91e-253 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IANDFCOA_02993 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
IANDFCOA_02994 1.05e-313 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IANDFCOA_02995 6.39e-234 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
IANDFCOA_02996 1.57e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IANDFCOA_02997 2.66e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IANDFCOA_02998 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
IANDFCOA_02999 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IANDFCOA_03000 4.77e-116 ysxD - - - - - - -
IANDFCOA_03001 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
IANDFCOA_03002 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IANDFCOA_03003 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
IANDFCOA_03004 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IANDFCOA_03005 5.13e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IANDFCOA_03006 3.19e-239 ysoA - - H - - - Tetratricopeptide repeat
IANDFCOA_03007 2.98e-147 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IANDFCOA_03008 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IANDFCOA_03009 4.3e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IANDFCOA_03010 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IANDFCOA_03011 3.91e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IANDFCOA_03012 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IANDFCOA_03013 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IANDFCOA_03015 1.71e-100 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
IANDFCOA_03016 2.64e-178 ysnF - - S - - - protein conserved in bacteria
IANDFCOA_03018 2.34e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
IANDFCOA_03019 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IANDFCOA_03020 2.04e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IANDFCOA_03021 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
IANDFCOA_03022 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IANDFCOA_03023 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
IANDFCOA_03024 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_03025 1.79e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
IANDFCOA_03026 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IANDFCOA_03027 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IANDFCOA_03028 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
IANDFCOA_03029 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
IANDFCOA_03030 3.96e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IANDFCOA_03031 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IANDFCOA_03032 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
IANDFCOA_03033 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
IANDFCOA_03035 1.23e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
IANDFCOA_03036 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
IANDFCOA_03037 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
IANDFCOA_03038 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_03039 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IANDFCOA_03040 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
IANDFCOA_03041 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IANDFCOA_03042 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
IANDFCOA_03043 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
IANDFCOA_03044 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IANDFCOA_03045 2.96e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IANDFCOA_03046 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IANDFCOA_03047 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IANDFCOA_03048 3.13e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IANDFCOA_03049 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
IANDFCOA_03050 2.51e-260 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
IANDFCOA_03051 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
IANDFCOA_03052 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
IANDFCOA_03053 2.94e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
IANDFCOA_03054 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
IANDFCOA_03055 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
IANDFCOA_03056 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
IANDFCOA_03057 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
IANDFCOA_03058 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
IANDFCOA_03059 3.72e-282 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IANDFCOA_03060 1.74e-186 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
IANDFCOA_03061 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IANDFCOA_03062 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
IANDFCOA_03063 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
IANDFCOA_03064 4.04e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IANDFCOA_03065 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
IANDFCOA_03066 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
IANDFCOA_03067 1.27e-59 ysdA - - S - - - Membrane
IANDFCOA_03068 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IANDFCOA_03069 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
IANDFCOA_03070 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IANDFCOA_03072 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IANDFCOA_03073 2.08e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IANDFCOA_03074 3.39e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
IANDFCOA_03075 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_03076 1.2e-190 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
IANDFCOA_03077 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IANDFCOA_03078 5.98e-206 ytxC - - S - - - YtxC-like family
IANDFCOA_03079 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
IANDFCOA_03080 2.46e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
IANDFCOA_03081 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
IANDFCOA_03082 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IANDFCOA_03083 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IANDFCOA_03084 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IANDFCOA_03085 9.85e-88 ytcD - - K - - - Transcriptional regulator
IANDFCOA_03086 1.12e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
IANDFCOA_03087 4.54e-205 ytbE - - S - - - reductase
IANDFCOA_03088 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IANDFCOA_03089 1.97e-137 ytaF - - P - - - Probably functions as a manganese efflux pump
IANDFCOA_03090 3.88e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IANDFCOA_03091 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IANDFCOA_03092 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
IANDFCOA_03093 3.27e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IANDFCOA_03094 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
IANDFCOA_03095 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
IANDFCOA_03096 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IANDFCOA_03097 9.38e-95 ytwI - - S - - - membrane
IANDFCOA_03098 6.42e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
IANDFCOA_03099 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
IANDFCOA_03100 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
IANDFCOA_03101 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IANDFCOA_03102 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IANDFCOA_03103 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IANDFCOA_03104 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IANDFCOA_03105 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
IANDFCOA_03106 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
IANDFCOA_03107 5.98e-111 ytrI - - - - - - -
IANDFCOA_03108 1.15e-39 - - - - - - - -
IANDFCOA_03109 1.02e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
IANDFCOA_03110 2.15e-63 ytpI - - S - - - YtpI-like protein
IANDFCOA_03111 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
IANDFCOA_03112 6.14e-204 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
IANDFCOA_03113 1.41e-304 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
IANDFCOA_03114 9.41e-164 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
IANDFCOA_03115 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IANDFCOA_03116 1.24e-61 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
IANDFCOA_03117 6.9e-234 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IANDFCOA_03118 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IANDFCOA_03119 2.64e-152 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IANDFCOA_03120 6.75e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IANDFCOA_03121 2.71e-192 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IANDFCOA_03122 2.15e-193 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IANDFCOA_03123 2.31e-127 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IANDFCOA_03124 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
IANDFCOA_03125 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
IANDFCOA_03126 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IANDFCOA_03128 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
IANDFCOA_03129 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
IANDFCOA_03130 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
IANDFCOA_03131 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IANDFCOA_03132 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
IANDFCOA_03133 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IANDFCOA_03134 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
IANDFCOA_03135 1.44e-149 ytfI - - S - - - Protein of unknown function (DUF2953)
IANDFCOA_03136 4.08e-112 yteJ - - S - - - RDD family
IANDFCOA_03137 9.73e-230 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
IANDFCOA_03138 1.69e-189 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IANDFCOA_03139 0.0 ytcJ - - S - - - amidohydrolase
IANDFCOA_03140 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IANDFCOA_03141 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
IANDFCOA_03142 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IANDFCOA_03143 1.07e-263 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IANDFCOA_03144 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IANDFCOA_03145 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IANDFCOA_03146 1.52e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IANDFCOA_03147 1.2e-141 yttP - - K - - - Transcriptional regulator
IANDFCOA_03148 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
IANDFCOA_03149 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
IANDFCOA_03150 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IANDFCOA_03152 1.85e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IANDFCOA_03153 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IANDFCOA_03154 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IANDFCOA_03155 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
IANDFCOA_03156 2.65e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
IANDFCOA_03157 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IANDFCOA_03158 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IANDFCOA_03159 4.86e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
IANDFCOA_03160 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IANDFCOA_03161 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
IANDFCOA_03162 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
IANDFCOA_03163 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IANDFCOA_03164 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
IANDFCOA_03165 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IANDFCOA_03166 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IANDFCOA_03167 2.06e-191 ytpQ - - S - - - Belongs to the UPF0354 family
IANDFCOA_03168 3.17e-75 ytpP - - CO - - - Thioredoxin
IANDFCOA_03169 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
IANDFCOA_03170 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
IANDFCOA_03171 1.17e-67 ytzB - - S - - - small secreted protein
IANDFCOA_03172 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IANDFCOA_03173 5.09e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IANDFCOA_03174 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IANDFCOA_03175 9.51e-61 ytzH - - S - - - YtzH-like protein
IANDFCOA_03176 3.02e-192 ytmP - - M - - - Phosphotransferase
IANDFCOA_03177 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
IANDFCOA_03178 9.05e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
IANDFCOA_03179 4.04e-211 ytlQ - - - - - - -
IANDFCOA_03180 4.29e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IANDFCOA_03181 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IANDFCOA_03182 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
IANDFCOA_03183 2.35e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
IANDFCOA_03184 3.51e-255 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
IANDFCOA_03185 5.66e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IANDFCOA_03186 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
IANDFCOA_03187 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IANDFCOA_03188 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IANDFCOA_03189 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
IANDFCOA_03190 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
IANDFCOA_03191 2.14e-36 yteV - - S - - - Sporulation protein Cse60
IANDFCOA_03192 3.13e-149 yteU - - S - - - Integral membrane protein
IANDFCOA_03193 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
IANDFCOA_03194 3.76e-91 yteS - - G - - - transport
IANDFCOA_03195 2.38e-278 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
IANDFCOA_03196 2.27e-221 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
IANDFCOA_03197 0.0 ytdP - - K - - - Transcriptional regulator
IANDFCOA_03198 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
IANDFCOA_03199 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
IANDFCOA_03200 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
IANDFCOA_03201 1.75e-276 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IANDFCOA_03202 1.86e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IANDFCOA_03203 2.57e-157 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IANDFCOA_03204 1.82e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IANDFCOA_03205 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IANDFCOA_03206 3.88e-180 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IANDFCOA_03207 1.13e-219 - - - S - - - Acetyl xylan esterase (AXE1)
IANDFCOA_03208 1.31e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_03209 7.39e-312 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IANDFCOA_03210 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IANDFCOA_03211 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IANDFCOA_03212 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
IANDFCOA_03213 7.08e-68 ytwF - - P - - - Sulfurtransferase
IANDFCOA_03214 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
IANDFCOA_03215 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
IANDFCOA_03216 3.14e-182 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IANDFCOA_03217 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
IANDFCOA_03218 5.75e-78 yttA - - S - - - Pfam Transposase IS66
IANDFCOA_03219 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
IANDFCOA_03220 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_03221 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
IANDFCOA_03222 2.07e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IANDFCOA_03223 6.91e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IANDFCOA_03224 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_03225 1.63e-163 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
IANDFCOA_03226 5.22e-187 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IANDFCOA_03227 1.4e-205 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_03228 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
IANDFCOA_03230 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
IANDFCOA_03231 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
IANDFCOA_03232 1.59e-135 ytqB - - J - - - Putative rRNA methylase
IANDFCOA_03233 2.29e-274 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
IANDFCOA_03234 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
IANDFCOA_03235 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IANDFCOA_03236 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IANDFCOA_03237 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IANDFCOA_03238 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IANDFCOA_03239 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IANDFCOA_03240 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
IANDFCOA_03241 3.86e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IANDFCOA_03242 1.26e-238 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IANDFCOA_03243 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IANDFCOA_03244 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IANDFCOA_03245 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IANDFCOA_03246 1.59e-81 ytkC - - S - - - Bacteriophage holin family
IANDFCOA_03247 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IANDFCOA_03249 5.58e-94 ytkA - - S - - - YtkA-like
IANDFCOA_03250 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IANDFCOA_03251 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IANDFCOA_03252 1.44e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
IANDFCOA_03253 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IANDFCOA_03254 6.96e-240 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IANDFCOA_03255 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
IANDFCOA_03256 2.65e-191 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IANDFCOA_03257 5.24e-296 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IANDFCOA_03258 6.12e-179 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IANDFCOA_03259 9.26e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IANDFCOA_03260 2.88e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IANDFCOA_03261 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IANDFCOA_03262 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IANDFCOA_03263 1.29e-192 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IANDFCOA_03264 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IANDFCOA_03265 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IANDFCOA_03266 7.13e-168 yteA - - T - - - COG1734 DnaK suppressor protein
IANDFCOA_03267 2.82e-195 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
IANDFCOA_03268 1.6e-307 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IANDFCOA_03269 1.23e-227 ytcB - - M - - - NAD-dependent epimerase dehydratase
IANDFCOA_03270 5.88e-297 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
IANDFCOA_03272 2.82e-262 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
IANDFCOA_03273 1.01e-275 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
IANDFCOA_03274 1.29e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
IANDFCOA_03275 1.9e-99 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
IANDFCOA_03276 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IANDFCOA_03277 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
IANDFCOA_03278 5.28e-238 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
IANDFCOA_03279 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IANDFCOA_03280 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IANDFCOA_03302 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IANDFCOA_03303 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
IANDFCOA_03304 1.2e-122 - - - M - - - FR47-like protein
IANDFCOA_03305 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
IANDFCOA_03306 4.82e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
IANDFCOA_03307 1.95e-109 yuaE - - S - - - DinB superfamily
IANDFCOA_03308 8.58e-139 yuaD - - - - - - -
IANDFCOA_03309 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
IANDFCOA_03310 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IANDFCOA_03311 3.53e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
IANDFCOA_03312 5.83e-118 yuaB - - - - - - -
IANDFCOA_03313 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IANDFCOA_03314 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
IANDFCOA_03315 3.31e-52 yubF - - S - - - yiaA/B two helix domain
IANDFCOA_03316 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IANDFCOA_03317 0.0 yubD - - P - - - Major Facilitator Superfamily
IANDFCOA_03318 1.61e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
IANDFCOA_03320 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IANDFCOA_03321 7.34e-254 yubA - - S - - - transporter activity
IANDFCOA_03322 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IANDFCOA_03323 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
IANDFCOA_03324 2.02e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
IANDFCOA_03325 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IANDFCOA_03326 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IANDFCOA_03327 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
IANDFCOA_03328 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IANDFCOA_03329 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IANDFCOA_03330 6.34e-300 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IANDFCOA_03331 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IANDFCOA_03332 1.06e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IANDFCOA_03333 5e-48 - - - - - - - -
IANDFCOA_03334 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
IANDFCOA_03335 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IANDFCOA_03336 1.25e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IANDFCOA_03337 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
IANDFCOA_03338 1.58e-50 - - - - - - - -
IANDFCOA_03339 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
IANDFCOA_03340 1.45e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
IANDFCOA_03341 9.97e-94 yugN - - S - - - YugN-like family
IANDFCOA_03343 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
IANDFCOA_03344 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
IANDFCOA_03345 8.16e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
IANDFCOA_03346 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
IANDFCOA_03347 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IANDFCOA_03348 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
IANDFCOA_03349 6.74e-112 alaR - - K - - - Transcriptional regulator
IANDFCOA_03350 9.89e-201 yugF - - I - - - Hydrolase
IANDFCOA_03351 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
IANDFCOA_03352 4.53e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IANDFCOA_03353 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_03354 1.44e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
IANDFCOA_03355 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
IANDFCOA_03357 8.9e-242 yuxJ - - EGP - - - Major facilitator superfamily
IANDFCOA_03358 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
IANDFCOA_03359 3.31e-98 yuxK - - S - - - protein conserved in bacteria
IANDFCOA_03360 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
IANDFCOA_03361 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IANDFCOA_03362 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IANDFCOA_03363 3.66e-253 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
IANDFCOA_03364 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_03365 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IANDFCOA_03366 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IANDFCOA_03367 3.25e-308 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
IANDFCOA_03368 1.73e-22 - - - - - - - -
IANDFCOA_03369 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IANDFCOA_03370 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IANDFCOA_03371 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IANDFCOA_03372 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IANDFCOA_03373 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IANDFCOA_03374 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IANDFCOA_03375 9.92e-78 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
IANDFCOA_03376 2.24e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
IANDFCOA_03377 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IANDFCOA_03378 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_03380 8.19e-169 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
IANDFCOA_03381 6.29e-10 - - - S - - - DegQ (SacQ) family
IANDFCOA_03382 8.73e-09 yuzC - - - - - - -
IANDFCOA_03383 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
IANDFCOA_03384 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IANDFCOA_03385 7.71e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
IANDFCOA_03386 3.64e-86 - - - S - - - Protein of unknown function (DUF1694)
IANDFCOA_03387 1.63e-52 yueH - - S - - - YueH-like protein
IANDFCOA_03388 2.05e-42 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
IANDFCOA_03389 5.5e-244 yueF - - S - - - transporter activity
IANDFCOA_03390 7.71e-91 - - - S - - - Protein of unknown function (DUF2283)
IANDFCOA_03391 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
IANDFCOA_03392 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
IANDFCOA_03393 2.04e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IANDFCOA_03394 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
IANDFCOA_03395 0.0 yueB - - S - - - type VII secretion protein EsaA
IANDFCOA_03396 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IANDFCOA_03397 3.93e-270 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
IANDFCOA_03398 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
IANDFCOA_03399 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
IANDFCOA_03400 2.84e-290 yukF - - QT - - - Transcriptional regulator
IANDFCOA_03401 3.3e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
IANDFCOA_03402 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
IANDFCOA_03403 4.08e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
IANDFCOA_03404 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IANDFCOA_03405 4.47e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
IANDFCOA_03406 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
IANDFCOA_03407 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IANDFCOA_03408 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IANDFCOA_03409 8.58e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
IANDFCOA_03410 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
IANDFCOA_03411 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
IANDFCOA_03412 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
IANDFCOA_03413 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IANDFCOA_03414 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
IANDFCOA_03415 3.14e-149 yuiC - - S - - - protein conserved in bacteria
IANDFCOA_03416 1.14e-45 yuiB - - S - - - Putative membrane protein
IANDFCOA_03417 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IANDFCOA_03418 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
IANDFCOA_03420 6.4e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IANDFCOA_03421 1.16e-148 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
IANDFCOA_03422 8.04e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IANDFCOA_03423 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
IANDFCOA_03424 3.2e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IANDFCOA_03425 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IANDFCOA_03426 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
IANDFCOA_03427 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IANDFCOA_03428 5.44e-74 yuzD - - S - - - protein conserved in bacteria
IANDFCOA_03429 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
IANDFCOA_03430 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
IANDFCOA_03431 1.48e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IANDFCOA_03432 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IANDFCOA_03433 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
IANDFCOA_03434 2.68e-254 yutH - - S - - - Spore coat protein
IANDFCOA_03435 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
IANDFCOA_03436 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IANDFCOA_03437 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
IANDFCOA_03438 3.2e-63 yutD - - S - - - protein conserved in bacteria
IANDFCOA_03439 2.71e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IANDFCOA_03440 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IANDFCOA_03441 7.63e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
IANDFCOA_03442 1.42e-168 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
IANDFCOA_03443 1.39e-64 yunC - - S - - - Domain of unknown function (DUF1805)
IANDFCOA_03444 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IANDFCOA_03445 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
IANDFCOA_03446 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
IANDFCOA_03447 1.07e-79 yunG - - - - - - -
IANDFCOA_03448 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IANDFCOA_03449 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
IANDFCOA_03450 1.99e-298 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
IANDFCOA_03451 3.71e-282 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
IANDFCOA_03452 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
IANDFCOA_03453 2.01e-70 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
IANDFCOA_03454 5.71e-121 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IANDFCOA_03455 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IANDFCOA_03456 6.5e-183 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IANDFCOA_03457 4.18e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
IANDFCOA_03458 3.87e-238 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IANDFCOA_03460 8.51e-306 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IANDFCOA_03461 7.78e-300 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IANDFCOA_03462 1.8e-215 bsn - - L - - - Ribonuclease
IANDFCOA_03463 2.42e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IANDFCOA_03464 5.04e-174 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
IANDFCOA_03465 5.1e-204 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
IANDFCOA_03466 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
IANDFCOA_03467 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IANDFCOA_03468 6.75e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
IANDFCOA_03469 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IANDFCOA_03470 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
IANDFCOA_03471 2.52e-262 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
IANDFCOA_03473 3.35e-56 - - - - - - - -
IANDFCOA_03474 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
IANDFCOA_03475 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
IANDFCOA_03476 1.14e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IANDFCOA_03477 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
IANDFCOA_03478 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IANDFCOA_03479 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IANDFCOA_03480 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
IANDFCOA_03481 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
IANDFCOA_03482 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IANDFCOA_03483 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
IANDFCOA_03484 2e-73 yusE - - CO - - - Thioredoxin
IANDFCOA_03485 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
IANDFCOA_03486 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
IANDFCOA_03487 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IANDFCOA_03488 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
IANDFCOA_03489 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IANDFCOA_03490 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
IANDFCOA_03491 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
IANDFCOA_03492 1.11e-13 - - - S - - - YuzL-like protein
IANDFCOA_03493 2.84e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IANDFCOA_03494 2.23e-54 - - - - - - - -
IANDFCOA_03495 8.66e-70 yusN - - M - - - Coat F domain
IANDFCOA_03496 4.47e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
IANDFCOA_03497 0.0 yusP - - P - - - Major facilitator superfamily
IANDFCOA_03498 2.93e-85 yusQ - - S - - - Tautomerase enzyme
IANDFCOA_03499 8.6e-139 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IANDFCOA_03500 8.42e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
IANDFCOA_03501 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
IANDFCOA_03502 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IANDFCOA_03503 2.86e-87 - - - S - - - YusW-like protein
IANDFCOA_03504 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
IANDFCOA_03505 1.1e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IANDFCOA_03506 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
IANDFCOA_03507 5.56e-305 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IANDFCOA_03508 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IANDFCOA_03509 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_03510 3.06e-204 yuxN - - K - - - Transcriptional regulator
IANDFCOA_03511 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IANDFCOA_03512 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
IANDFCOA_03513 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IANDFCOA_03514 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IANDFCOA_03515 3.48e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
IANDFCOA_03516 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IANDFCOA_03517 2.74e-244 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_03518 7.65e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
IANDFCOA_03519 2.48e-166 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
IANDFCOA_03520 2.44e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IANDFCOA_03521 6.17e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
IANDFCOA_03522 6.23e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IANDFCOA_03523 2.96e-130 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
IANDFCOA_03524 3.76e-316 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IANDFCOA_03525 6.35e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IANDFCOA_03526 5.15e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IANDFCOA_03527 5.21e-182 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IANDFCOA_03528 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
IANDFCOA_03529 0.0 yvrG - - T - - - Histidine kinase
IANDFCOA_03530 2.08e-169 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IANDFCOA_03531 5.07e-32 - - - - - - - -
IANDFCOA_03532 4.06e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
IANDFCOA_03533 3.46e-26 - - - S - - - YvrJ protein family
IANDFCOA_03534 1.59e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IANDFCOA_03535 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
IANDFCOA_03536 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IANDFCOA_03537 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_03538 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
IANDFCOA_03540 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IANDFCOA_03541 3.76e-223 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IANDFCOA_03542 2e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IANDFCOA_03543 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IANDFCOA_03545 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
IANDFCOA_03546 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
IANDFCOA_03547 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
IANDFCOA_03548 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
IANDFCOA_03549 4.91e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
IANDFCOA_03550 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
IANDFCOA_03551 1.95e-150 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
IANDFCOA_03552 6.19e-201 yvgN - - S - - - reductase
IANDFCOA_03553 7.97e-113 yvgO - - - - - - -
IANDFCOA_03554 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
IANDFCOA_03555 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IANDFCOA_03556 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IANDFCOA_03557 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IANDFCOA_03559 2.34e-139 yvgT - - S - - - membrane
IANDFCOA_03560 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
IANDFCOA_03561 3.45e-137 bdbD - - O - - - Thioredoxin
IANDFCOA_03562 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IANDFCOA_03563 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
IANDFCOA_03564 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
IANDFCOA_03565 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
IANDFCOA_03566 1.4e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IANDFCOA_03567 2.08e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IANDFCOA_03568 0.0 - - - S - - - Fusaric acid resistance protein-like
IANDFCOA_03569 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
IANDFCOA_03570 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
IANDFCOA_03571 1.51e-123 - - - K - - - Bacterial regulatory proteins, tetR family
IANDFCOA_03572 9.32e-181 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IANDFCOA_03574 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IANDFCOA_03575 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IANDFCOA_03576 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
IANDFCOA_03577 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
IANDFCOA_03578 5.5e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
IANDFCOA_03579 3.44e-48 yvzC - - K - - - transcriptional
IANDFCOA_03580 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
IANDFCOA_03581 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
IANDFCOA_03582 3.85e-72 yvaP - - K - - - transcriptional
IANDFCOA_03583 1.61e-188 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IANDFCOA_03584 6.69e-134 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IANDFCOA_03585 1.31e-143 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IANDFCOA_03586 3.37e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IANDFCOA_03587 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IANDFCOA_03588 8.57e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IANDFCOA_03589 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IANDFCOA_03590 1.37e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IANDFCOA_03591 4.11e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IANDFCOA_03592 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IANDFCOA_03593 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IANDFCOA_03594 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IANDFCOA_03595 7.95e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
IANDFCOA_03596 9.9e-144 yvbH - - S - - - YvbH-like oligomerisation region
IANDFCOA_03597 1.61e-156 yvbI - - M - - - Membrane
IANDFCOA_03598 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
IANDFCOA_03599 6.87e-106 yvbK - - K - - - acetyltransferase
IANDFCOA_03600 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IANDFCOA_03601 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
IANDFCOA_03602 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IANDFCOA_03603 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
IANDFCOA_03604 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IANDFCOA_03605 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IANDFCOA_03606 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IANDFCOA_03607 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
IANDFCOA_03608 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IANDFCOA_03610 5.49e-205 yvbU - - K - - - Transcriptional regulator
IANDFCOA_03611 3.93e-198 yvbV - - EG - - - EamA-like transporter family
IANDFCOA_03612 1.43e-306 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IANDFCOA_03613 1.22e-248 - - - S - - - Glycosyl hydrolase
IANDFCOA_03614 2.92e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IANDFCOA_03615 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IANDFCOA_03616 2.6e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IANDFCOA_03617 2.52e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IANDFCOA_03618 7.33e-250 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_03619 9.7e-169 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IANDFCOA_03620 5.95e-209 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
IANDFCOA_03621 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
IANDFCOA_03622 8.02e-261 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
IANDFCOA_03623 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
IANDFCOA_03624 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
IANDFCOA_03625 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
IANDFCOA_03626 1.3e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
IANDFCOA_03627 1.68e-294 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
IANDFCOA_03628 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_03629 1.18e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
IANDFCOA_03630 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IANDFCOA_03631 3.35e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IANDFCOA_03632 5.69e-44 yvfG - - S - - - YvfG protein
IANDFCOA_03633 7.54e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
IANDFCOA_03634 1.91e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
IANDFCOA_03635 8.22e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IANDFCOA_03636 7.83e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IANDFCOA_03637 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IANDFCOA_03638 2.36e-246 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IANDFCOA_03639 4.13e-254 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
IANDFCOA_03640 3.5e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IANDFCOA_03641 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
IANDFCOA_03642 5.9e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IANDFCOA_03643 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
IANDFCOA_03644 4.5e-281 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
IANDFCOA_03645 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IANDFCOA_03646 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IANDFCOA_03647 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
IANDFCOA_03648 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
IANDFCOA_03649 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
IANDFCOA_03651 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
IANDFCOA_03652 7.42e-95 - - - S - - - Protein of unknown function (DUF3237)
IANDFCOA_03653 1.76e-162 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
IANDFCOA_03654 0.0 pbpE - - V - - - Beta-lactamase
IANDFCOA_03655 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
IANDFCOA_03656 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IANDFCOA_03657 0.0 ybeC - - E - - - amino acid
IANDFCOA_03658 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
IANDFCOA_03659 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IANDFCOA_03660 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
IANDFCOA_03661 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
IANDFCOA_03662 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
IANDFCOA_03663 9.45e-234 - - - S - - - Patatin-like phospholipase
IANDFCOA_03665 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IANDFCOA_03666 2.91e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IANDFCOA_03667 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IANDFCOA_03668 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
IANDFCOA_03669 3.96e-197 malA - - S - - - Protein of unknown function (DUF1189)
IANDFCOA_03670 6.84e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
IANDFCOA_03671 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
IANDFCOA_03672 1.63e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
IANDFCOA_03673 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
IANDFCOA_03674 1.54e-221 yvdE - - K - - - Transcriptional regulator
IANDFCOA_03675 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
IANDFCOA_03676 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
IANDFCOA_03677 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IANDFCOA_03678 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IANDFCOA_03679 1.15e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IANDFCOA_03680 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
IANDFCOA_03681 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_03682 1.32e-249 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
IANDFCOA_03683 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IANDFCOA_03684 1.37e-45 - - - - - - - -
IANDFCOA_03685 8.35e-185 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
IANDFCOA_03686 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
IANDFCOA_03687 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
IANDFCOA_03688 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
IANDFCOA_03689 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
IANDFCOA_03690 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IANDFCOA_03691 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IANDFCOA_03692 2.18e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
IANDFCOA_03693 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
IANDFCOA_03694 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
IANDFCOA_03696 0.0 - - - - - - - -
IANDFCOA_03697 6.36e-172 - - - - - - - -
IANDFCOA_03698 2.61e-146 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
IANDFCOA_03699 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IANDFCOA_03700 1.32e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IANDFCOA_03701 1.15e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IANDFCOA_03702 2.87e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
IANDFCOA_03703 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IANDFCOA_03704 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IANDFCOA_03705 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IANDFCOA_03706 5.03e-178 yvpB - - NU - - - protein conserved in bacteria
IANDFCOA_03707 1.1e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
IANDFCOA_03708 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IANDFCOA_03709 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IANDFCOA_03710 3.72e-211 yvoD - - P - - - COG0370 Fe2 transport system protein B
IANDFCOA_03711 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IANDFCOA_03712 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IANDFCOA_03713 9.39e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
IANDFCOA_03714 2.12e-166 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IANDFCOA_03715 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
IANDFCOA_03716 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
IANDFCOA_03717 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
IANDFCOA_03718 9.32e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IANDFCOA_03719 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
IANDFCOA_03720 1.03e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
IANDFCOA_03721 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
IANDFCOA_03722 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
IANDFCOA_03723 2.49e-35 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
IANDFCOA_03724 1.12e-218 yvlB - - S - - - Putative adhesin
IANDFCOA_03725 3.3e-64 yvlA - - - - - - -
IANDFCOA_03726 2.25e-45 yvkN - - - - - - -
IANDFCOA_03727 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IANDFCOA_03728 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IANDFCOA_03729 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IANDFCOA_03730 2.54e-42 csbA - - S - - - protein conserved in bacteria
IANDFCOA_03731 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
IANDFCOA_03732 5.81e-131 yvkB - - K - - - Transcriptional regulator
IANDFCOA_03733 3.03e-295 yvkA - - P - - - -transporter
IANDFCOA_03734 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IANDFCOA_03735 1.38e-73 swrA - - S - - - Swarming motility protein
IANDFCOA_03736 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IANDFCOA_03737 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IANDFCOA_03738 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
IANDFCOA_03739 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IANDFCOA_03740 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IANDFCOA_03741 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IANDFCOA_03742 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IANDFCOA_03743 1e-131 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IANDFCOA_03744 9.14e-88 - - - - - - - -
IANDFCOA_03745 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
IANDFCOA_03746 8.56e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
IANDFCOA_03747 8.97e-313 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IANDFCOA_03748 1.62e-69 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
IANDFCOA_03749 1.43e-124 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IANDFCOA_03750 5.02e-39 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IANDFCOA_03751 5e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IANDFCOA_03752 6.92e-92 yviE - - - - - - -
IANDFCOA_03753 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
IANDFCOA_03754 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
IANDFCOA_03755 7.06e-102 yvyG - - NOU - - - FlgN protein
IANDFCOA_03756 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
IANDFCOA_03757 1.83e-96 yvyF - - S - - - flagellar protein
IANDFCOA_03758 7.56e-161 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
IANDFCOA_03759 1.04e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
IANDFCOA_03760 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IANDFCOA_03761 2.15e-199 degV - - S - - - protein conserved in bacteria
IANDFCOA_03762 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IANDFCOA_03763 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IANDFCOA_03764 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
IANDFCOA_03765 8.05e-225 yvhJ - - K - - - Transcriptional regulator
IANDFCOA_03766 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IANDFCOA_03767 3.69e-300 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
IANDFCOA_03768 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IANDFCOA_03769 5.79e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
IANDFCOA_03770 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
IANDFCOA_03771 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IANDFCOA_03772 5.68e-279 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
IANDFCOA_03773 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IANDFCOA_03774 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IANDFCOA_03775 9e-109 - - - M - - - Glycosyltransferase like family 2
IANDFCOA_03776 6.43e-265 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IANDFCOA_03777 0.0 lytB - - D - - - Stage II sporulation protein
IANDFCOA_03778 9.07e-16 - - - - - - - -
IANDFCOA_03779 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IANDFCOA_03780 2.21e-276 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IANDFCOA_03781 1.48e-103 - - - M - - - Glycosyltransferase like family 2
IANDFCOA_03782 5.45e-117 - - - M - - - Glycosyl transferases group 1
IANDFCOA_03784 3.9e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IANDFCOA_03785 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IANDFCOA_03786 1.67e-168 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
IANDFCOA_03787 7.8e-102 - - - - - - - -
IANDFCOA_03788 3.8e-68 - - - - - - - -
IANDFCOA_03789 5.36e-249 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IANDFCOA_03790 4.14e-106 - - - M - - - Glycosyltransferase like family 2
IANDFCOA_03791 6.53e-180 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IANDFCOA_03792 1.32e-73 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
IANDFCOA_03793 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IANDFCOA_03794 1.01e-129 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IANDFCOA_03795 2.07e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
IANDFCOA_03796 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
IANDFCOA_03797 6.69e-110 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IANDFCOA_03798 8.14e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IANDFCOA_03799 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IANDFCOA_03800 2.73e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IANDFCOA_03801 3.12e-310 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
IANDFCOA_03802 3.4e-238 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IANDFCOA_03803 1.95e-251 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
IANDFCOA_03804 2.27e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IANDFCOA_03805 2.02e-220 ywtF_2 - - K - - - Transcriptional regulator
IANDFCOA_03806 4.69e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IANDFCOA_03807 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IANDFCOA_03808 2.29e-29 ywtC - - - - - - -
IANDFCOA_03809 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IANDFCOA_03810 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
IANDFCOA_03811 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
IANDFCOA_03812 1.55e-226 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
IANDFCOA_03813 1.85e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IANDFCOA_03814 4.61e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IANDFCOA_03815 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IANDFCOA_03816 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IANDFCOA_03817 9.04e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
IANDFCOA_03818 1.62e-118 batE - - T - - - Sh3 type 3 domain protein
IANDFCOA_03819 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
IANDFCOA_03820 8.76e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
IANDFCOA_03821 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
IANDFCOA_03822 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
IANDFCOA_03823 3.36e-218 alsR - - K - - - LysR substrate binding domain
IANDFCOA_03824 1.68e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IANDFCOA_03825 2.5e-161 ywrJ - - - - - - -
IANDFCOA_03826 1.37e-194 cotB - - - ko:K06325 - ko00000 -
IANDFCOA_03827 2.64e-268 cotH - - M ko:K06330 - ko00000 Spore Coat
IANDFCOA_03828 2.17e-16 - - - - - - - -
IANDFCOA_03829 1.77e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IANDFCOA_03830 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
IANDFCOA_03831 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IANDFCOA_03832 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IANDFCOA_03833 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
IANDFCOA_03834 3.51e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
IANDFCOA_03836 6.11e-129 ywqN - - S - - - NAD(P)H-dependent
IANDFCOA_03837 3.33e-209 - - - K - - - Transcriptional regulator
IANDFCOA_03838 8.51e-155 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IANDFCOA_03839 1.13e-126 - - - - - - - -
IANDFCOA_03841 2.2e-66 - - - - - - - -
IANDFCOA_03842 1.29e-97 - - - - - - - -
IANDFCOA_03843 1.95e-297 ywqJ - - S - - - Pre-toxin TG
IANDFCOA_03844 4.98e-50 ywqI - - S - - - Family of unknown function (DUF5344)
IANDFCOA_03846 1.71e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
IANDFCOA_03847 1.34e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IANDFCOA_03848 1.18e-178 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
IANDFCOA_03849 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IANDFCOA_03850 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
IANDFCOA_03851 3.6e-25 - - - - - - - -
IANDFCOA_03852 0.0 ywqB - - S - - - SWIM zinc finger
IANDFCOA_03853 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IANDFCOA_03854 1.45e-199 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IANDFCOA_03855 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IANDFCOA_03856 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
IANDFCOA_03857 3.56e-86 ywpG - - - - - - -
IANDFCOA_03858 3.59e-88 ywpF - - S - - - YwpF-like protein
IANDFCOA_03859 6.34e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
IANDFCOA_03860 2.51e-18 - - - M - - - cell wall anchor domain
IANDFCOA_03861 1.28e-66 ywpD - - T - - - Histidine kinase
IANDFCOA_03862 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IANDFCOA_03863 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IANDFCOA_03864 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
IANDFCOA_03865 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IANDFCOA_03866 9.79e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IANDFCOA_03867 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
IANDFCOA_03868 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
IANDFCOA_03869 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
IANDFCOA_03870 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IANDFCOA_03871 7.65e-308 ywoF - - P - - - Right handed beta helix region
IANDFCOA_03872 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
IANDFCOA_03873 5.39e-307 ywoD - - EGP - - - Major facilitator superfamily
IANDFCOA_03874 1.04e-133 yjgF - - Q - - - Isochorismatase family
IANDFCOA_03875 5.04e-101 - - - - - - - -
IANDFCOA_03876 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
IANDFCOA_03877 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
IANDFCOA_03878 3.48e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
IANDFCOA_03879 6.63e-95 ywnJ - - S - - - VanZ like family
IANDFCOA_03880 1.3e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IANDFCOA_03881 3.01e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
IANDFCOA_03882 1.29e-16 ywnC - - S - - - Family of unknown function (DUF5362)
IANDFCOA_03883 1.43e-91 ywnF - - S - - - Family of unknown function (DUF5392)
IANDFCOA_03884 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IANDFCOA_03885 2.31e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
IANDFCOA_03886 1.24e-77 ywnC - - S - - - Family of unknown function (DUF5362)
IANDFCOA_03887 1.02e-145 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
IANDFCOA_03888 4.58e-85 ywnA - - K - - - Transcriptional regulator
IANDFCOA_03889 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IANDFCOA_03890 7.55e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
IANDFCOA_03891 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
IANDFCOA_03893 1.84e-20 csbD - - K - - - CsbD-like
IANDFCOA_03894 1.12e-109 ywmF - - S - - - Peptidase M50
IANDFCOA_03895 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IANDFCOA_03896 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IANDFCOA_03897 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IANDFCOA_03899 1.44e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IANDFCOA_03900 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IANDFCOA_03901 9.77e-234 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
IANDFCOA_03902 1e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IANDFCOA_03903 2.68e-171 ywmB - - S - - - TATA-box binding
IANDFCOA_03904 4.54e-45 ywzB - - S - - - membrane
IANDFCOA_03905 4.84e-112 ywmA - - - - - - -
IANDFCOA_03906 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
IANDFCOA_03907 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IANDFCOA_03908 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IANDFCOA_03909 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IANDFCOA_03910 2.89e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IANDFCOA_03911 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IANDFCOA_03912 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IANDFCOA_03913 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
IANDFCOA_03914 2.23e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
IANDFCOA_03915 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IANDFCOA_03916 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IANDFCOA_03917 2.9e-122 ywlG - - S - - - Belongs to the UPF0340 family
IANDFCOA_03918 1.36e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
IANDFCOA_03919 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IANDFCOA_03920 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
IANDFCOA_03921 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IANDFCOA_03922 1.04e-99 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
IANDFCOA_03923 1.55e-150 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
IANDFCOA_03924 5.61e-73 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IANDFCOA_03926 2.23e-200 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IANDFCOA_03927 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IANDFCOA_03928 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IANDFCOA_03929 6.01e-117 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IANDFCOA_03930 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
IANDFCOA_03931 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IANDFCOA_03932 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
IANDFCOA_03933 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
IANDFCOA_03934 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IANDFCOA_03935 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
IANDFCOA_03936 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IANDFCOA_03937 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IANDFCOA_03938 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
IANDFCOA_03939 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
IANDFCOA_03940 3.86e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
IANDFCOA_03941 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IANDFCOA_03942 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IANDFCOA_03943 1.65e-266 acdA - - I - - - acyl-CoA dehydrogenase
IANDFCOA_03944 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
IANDFCOA_03945 9.57e-287 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IANDFCOA_03946 2.82e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IANDFCOA_03947 1.32e-57 ywjC - - - - - - -
IANDFCOA_03948 7.5e-122 ywjB - - H - - - RibD C-terminal domain
IANDFCOA_03949 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
IANDFCOA_03950 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IANDFCOA_03951 2.06e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
IANDFCOA_03952 2.28e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
IANDFCOA_03953 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
IANDFCOA_03954 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IANDFCOA_03955 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
IANDFCOA_03956 1.84e-179 ywiC - - S - - - YwiC-like protein
IANDFCOA_03957 3.98e-169 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
IANDFCOA_03958 1.2e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IANDFCOA_03959 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
IANDFCOA_03960 4.64e-96 ywiB - - S - - - protein conserved in bacteria
IANDFCOA_03961 3.71e-12 - - - S - - - Bacteriocin subtilosin A
IANDFCOA_03962 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
IANDFCOA_03964 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IANDFCOA_03965 1.46e-298 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
IANDFCOA_03966 4.88e-276 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
IANDFCOA_03967 0.0 - - - L - - - Peptidase, M16
IANDFCOA_03969 0.0 ywhL - - CO - - - amine dehydrogenase activity
IANDFCOA_03970 9.47e-275 ywhK - - CO - - - amine dehydrogenase activity
IANDFCOA_03971 6.56e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IANDFCOA_03975 1.3e-10 - - - - - - - -
IANDFCOA_03978 1.4e-74 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IANDFCOA_03980 1.42e-213 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IANDFCOA_03981 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IANDFCOA_03982 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IANDFCOA_03983 5.51e-123 ywhD - - S - - - YwhD family
IANDFCOA_03984 3.29e-154 ywhC - - S - - - Peptidase family M50
IANDFCOA_03985 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
IANDFCOA_03986 1.45e-93 ywhA - - K - - - Transcriptional regulator
IANDFCOA_03987 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IANDFCOA_03989 2.66e-263 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
IANDFCOA_03990 6.12e-20 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
IANDFCOA_03991 1.28e-102 yffB - - K - - - Transcriptional regulator
IANDFCOA_03992 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
IANDFCOA_03993 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
IANDFCOA_03994 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
IANDFCOA_03995 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
IANDFCOA_03996 3.69e-201 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
IANDFCOA_03997 2.51e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IANDFCOA_03998 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_03999 7.1e-226 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
IANDFCOA_04000 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
IANDFCOA_04001 3.52e-178 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
IANDFCOA_04002 1.89e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
IANDFCOA_04003 1.36e-268 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IANDFCOA_04004 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IANDFCOA_04005 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IANDFCOA_04006 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IANDFCOA_04007 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IANDFCOA_04008 1.09e-274 ywfA - - EGP - - - -transporter
IANDFCOA_04009 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IANDFCOA_04010 0.0 rocB - - E - - - arginine degradation protein
IANDFCOA_04011 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IANDFCOA_04012 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IANDFCOA_04013 1.1e-102 - - - - - - - -
IANDFCOA_04014 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
IANDFCOA_04015 2.44e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IANDFCOA_04016 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IANDFCOA_04017 2.6e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IANDFCOA_04018 2.54e-243 spsG - - M - - - Spore Coat
IANDFCOA_04019 4.64e-169 spsF - - M ko:K07257 - ko00000 Spore Coat
IANDFCOA_04020 1.13e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
IANDFCOA_04021 4.22e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
IANDFCOA_04022 1.85e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
IANDFCOA_04023 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
IANDFCOA_04024 2.32e-186 spsA - - M - - - Spore Coat
IANDFCOA_04025 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IANDFCOA_04026 1.59e-78 ywdK - - S - - - small membrane protein
IANDFCOA_04027 1.86e-303 ywdJ - - F - - - Xanthine uracil
IANDFCOA_04028 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
IANDFCOA_04029 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IANDFCOA_04030 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IANDFCOA_04031 1.9e-191 ywdF - - S - - - Glycosyltransferase like family 2
IANDFCOA_04033 8.74e-146 ywdD - - - - - - -
IANDFCOA_04034 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
IANDFCOA_04035 7.39e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IANDFCOA_04036 6.19e-39 ywdA - - - - - - -
IANDFCOA_04037 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IANDFCOA_04038 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IANDFCOA_04039 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
IANDFCOA_04040 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IANDFCOA_04042 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IANDFCOA_04043 1.4e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IANDFCOA_04044 2.31e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
IANDFCOA_04045 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
IANDFCOA_04046 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
IANDFCOA_04047 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IANDFCOA_04048 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IANDFCOA_04049 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IANDFCOA_04050 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IANDFCOA_04051 5.11e-49 ydaS - - S - - - membrane
IANDFCOA_04052 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IANDFCOA_04053 1.12e-290 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IANDFCOA_04054 2.25e-75 gtcA - - S - - - GtrA-like protein
IANDFCOA_04055 3.42e-158 ywcC - - K - - - transcriptional regulator
IANDFCOA_04057 6.1e-64 ywcB - - S - - - Protein of unknown function, DUF485
IANDFCOA_04058 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IANDFCOA_04059 1.03e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IANDFCOA_04060 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
IANDFCOA_04061 1.4e-245 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
IANDFCOA_04062 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
IANDFCOA_04063 1e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IANDFCOA_04064 1.32e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IANDFCOA_04065 2.7e-203 ywbI - - K - - - Transcriptional regulator
IANDFCOA_04066 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IANDFCOA_04067 1.21e-143 ywbG - - M - - - effector of murein hydrolase
IANDFCOA_04068 1.76e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
IANDFCOA_04069 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
IANDFCOA_04070 4e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
IANDFCOA_04071 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
IANDFCOA_04072 1.59e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IANDFCOA_04073 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IANDFCOA_04074 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IANDFCOA_04075 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IANDFCOA_04076 4.41e-215 gspA - - M - - - General stress
IANDFCOA_04077 1.66e-156 ywaF - - S - - - Integral membrane protein
IANDFCOA_04078 4.18e-113 ywaE - - K - - - Transcriptional regulator
IANDFCOA_04079 1.56e-297 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IANDFCOA_04080 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
IANDFCOA_04081 4.38e-115 - - - K - - - Helix-turn-helix XRE-family like proteins
IANDFCOA_04082 7.93e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
IANDFCOA_04083 2.79e-165 - - - EGP - - - Permeases of the major facilitator superfamily
IANDFCOA_04084 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
IANDFCOA_04085 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
IANDFCOA_04086 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IANDFCOA_04087 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
IANDFCOA_04088 1.61e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IANDFCOA_04089 8.26e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IANDFCOA_04090 8e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IANDFCOA_04091 3.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IANDFCOA_04092 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IANDFCOA_04093 1.18e-67 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IANDFCOA_04094 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IANDFCOA_04095 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
IANDFCOA_04096 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
IANDFCOA_04097 8.94e-28 yxzF - - - - - - -
IANDFCOA_04098 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
IANDFCOA_04099 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IANDFCOA_04100 3.23e-270 yxlH - - EGP - - - Major Facilitator Superfamily
IANDFCOA_04101 4.96e-173 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IANDFCOA_04102 1.65e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_04103 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
IANDFCOA_04104 1.75e-43 - - - - - - - -
IANDFCOA_04105 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
IANDFCOA_04106 1.06e-123 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IANDFCOA_04107 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
IANDFCOA_04108 1.52e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IANDFCOA_04109 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
IANDFCOA_04110 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
IANDFCOA_04111 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
IANDFCOA_04112 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IANDFCOA_04113 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
IANDFCOA_04114 0.0 - - - O - - - Peptidase family M48
IANDFCOA_04116 7.49e-199 yxkH - - G - - - Polysaccharide deacetylase
IANDFCOA_04117 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IANDFCOA_04118 3.89e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
IANDFCOA_04119 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IANDFCOA_04120 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IANDFCOA_04121 1.66e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
IANDFCOA_04122 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IANDFCOA_04123 7.69e-100 - - - S - - - Protein of unknown function (DUF1453)
IANDFCOA_04124 4.59e-257 - - - T - - - Signal transduction histidine kinase
IANDFCOA_04125 4.65e-149 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
IANDFCOA_04126 2.6e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
IANDFCOA_04129 1.43e-111 yxjI - - S - - - LURP-one-related
IANDFCOA_04130 1.28e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
IANDFCOA_04131 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
IANDFCOA_04132 6.8e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IANDFCOA_04133 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IANDFCOA_04134 3.82e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IANDFCOA_04135 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
IANDFCOA_04136 8.81e-204 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
IANDFCOA_04137 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IANDFCOA_04138 2.83e-131 - - - T - - - Domain of unknown function (DUF4163)
IANDFCOA_04139 5.39e-62 yxiS - - - - - - -
IANDFCOA_04140 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IANDFCOA_04141 3.31e-283 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IANDFCOA_04142 1.46e-182 bglS - - M - - - licheninase activity
IANDFCOA_04143 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IANDFCOA_04144 4.37e-142 - - - - - - - -
IANDFCOA_04145 4.43e-291 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
IANDFCOA_04146 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IANDFCOA_04147 2.37e-272 - - - E - - - GDSL-like Lipase/Acylhydrolase
IANDFCOA_04148 1.86e-70 - - - K - - - Transcriptional regulator PadR-like family
IANDFCOA_04149 2.16e-53 - - - S - - - Protein of unknown function (DUF2812)
IANDFCOA_04150 2.34e-21 - - - S - - - YxiJ-like protein
IANDFCOA_04151 0.0 wapA - - M - - - COG3209 Rhs family protein
IANDFCOA_04152 8.44e-210 yxxF - - EG - - - EamA-like transporter family
IANDFCOA_04153 2.2e-28 - - - - - - - -
IANDFCOA_04154 2.01e-75 - - - K - - - helix_turn_helix, mercury resistance
IANDFCOA_04156 1.24e-113 - - - - - - - -
IANDFCOA_04157 2.77e-35 - - - S - - - Sporulation delaying protein SdpA
IANDFCOA_04158 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
IANDFCOA_04159 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IANDFCOA_04160 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IANDFCOA_04161 1.33e-62 - - - - - - - -
IANDFCOA_04162 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
IANDFCOA_04163 6.09e-292 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
IANDFCOA_04165 2.81e-26 - - - S - - - protein conserved in bacteria
IANDFCOA_04167 2.14e-156 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
IANDFCOA_04168 4.47e-51 yxiC - - S - - - Family of unknown function (DUF5344)
IANDFCOA_04169 2.18e-36 - - - S - - - Domain of unknown function (DUF5082)
IANDFCOA_04170 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IANDFCOA_04171 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IANDFCOA_04172 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
IANDFCOA_04173 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IANDFCOA_04174 8.72e-297 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
IANDFCOA_04175 8.04e-230 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IANDFCOA_04176 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IANDFCOA_04177 6.66e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
IANDFCOA_04178 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IANDFCOA_04179 4.8e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IANDFCOA_04180 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IANDFCOA_04181 1.76e-195 - - - S - - - Domain of Unknown Function (DUF1206)
IANDFCOA_04182 7.72e-256 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
IANDFCOA_04183 1.39e-312 yxeQ - - S - - - MmgE/PrpD family
IANDFCOA_04184 2.65e-268 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
IANDFCOA_04185 2.78e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_04186 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IANDFCOA_04187 5.02e-185 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IANDFCOA_04188 1.54e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IANDFCOA_04189 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IANDFCOA_04190 9.11e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
IANDFCOA_04191 3.29e-193 yxeH - - S - - - hydrolases of the HAD superfamily
IANDFCOA_04194 7.32e-42 yxeE - - - - - - -
IANDFCOA_04195 7.57e-28 yxeD - - - - - - -
IANDFCOA_04196 6.79e-91 - - - - - - - -
IANDFCOA_04197 4.99e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IANDFCOA_04198 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
IANDFCOA_04199 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IANDFCOA_04200 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IANDFCOA_04201 2.7e-231 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_04202 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IANDFCOA_04203 2.83e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IANDFCOA_04204 1.09e-186 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IANDFCOA_04205 5.13e-211 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
IANDFCOA_04206 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IANDFCOA_04207 4.68e-295 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
IANDFCOA_04208 1.74e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IANDFCOA_04209 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IANDFCOA_04210 6.09e-228 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IANDFCOA_04211 9.89e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IANDFCOA_04212 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IANDFCOA_04213 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IANDFCOA_04214 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
IANDFCOA_04216 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
IANDFCOA_04217 6.88e-312 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IANDFCOA_04218 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
IANDFCOA_04220 8.38e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IANDFCOA_04221 1.03e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
IANDFCOA_04222 2.4e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IANDFCOA_04223 2.09e-16 yxaI - - S - - - membrane protein domain
IANDFCOA_04224 1.73e-135 yxaL - - S - - - PQQ-like domain
IANDFCOA_04225 7.22e-79 - - - S - - - Family of unknown function (DUF5391)
IANDFCOA_04226 4.03e-99 yxaI - - S - - - membrane protein domain
IANDFCOA_04227 4.89e-282 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
IANDFCOA_04228 1.22e-249 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
IANDFCOA_04229 1.59e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IANDFCOA_04230 1.5e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IANDFCOA_04231 3.95e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IANDFCOA_04232 5.96e-77 - - - S ko:K06518 - ko00000,ko02000 LrgA family
IANDFCOA_04233 7.33e-152 yxaC - - M - - - effector of murein hydrolase
IANDFCOA_04234 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
IANDFCOA_04235 1.64e-263 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
IANDFCOA_04236 2.56e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
IANDFCOA_04237 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
IANDFCOA_04238 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
IANDFCOA_04239 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IANDFCOA_04240 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
IANDFCOA_04241 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
IANDFCOA_04242 5.52e-238 - - - S - - - Polysaccharide pyruvyl transferase
IANDFCOA_04243 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IANDFCOA_04244 8.38e-44 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IANDFCOA_04245 1.23e-162 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
IANDFCOA_04246 2.4e-23 - - - - - - - -
IANDFCOA_04247 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
IANDFCOA_04248 0.0 - - - L - - - AAA domain
IANDFCOA_04249 4e-309 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
IANDFCOA_04250 3.64e-56 - - - S - - - MazG-like family
IANDFCOA_04251 1.36e-141 - - - S - - - Caspase domain
IANDFCOA_04252 1.23e-134 - - - L - - - reverse transcriptase
IANDFCOA_04254 7.1e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IANDFCOA_04256 2.24e-87 - - - - - - - -
IANDFCOA_04257 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IANDFCOA_04259 6.44e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
IANDFCOA_04260 2.95e-264 yycP - - - - - - -
IANDFCOA_04261 1.96e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IANDFCOA_04262 5.25e-111 yycN - - K - - - Acetyltransferase
IANDFCOA_04263 1.06e-239 - - - S - - - aspartate phosphatase
IANDFCOA_04265 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IANDFCOA_04266 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IANDFCOA_04267 8.29e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
IANDFCOA_04268 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IANDFCOA_04269 5.58e-216 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IANDFCOA_04270 2.36e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
IANDFCOA_04271 9.34e-98 - - - S - - - Peptidase propeptide and YPEB domain
IANDFCOA_04272 2.2e-42 - - - S - - - Peptidase propeptide and YPEB domain
IANDFCOA_04273 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IANDFCOA_04274 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IANDFCOA_04275 2.83e-199 yycI - - S - - - protein conserved in bacteria
IANDFCOA_04276 0.0 yycH - - S - - - protein conserved in bacteria
IANDFCOA_04277 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IANDFCOA_04278 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IANDFCOA_04283 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IANDFCOA_04284 3.85e-98 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IANDFCOA_04285 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
IANDFCOA_04286 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
IANDFCOA_04288 1.89e-22 yycC - - K - - - YycC-like protein
IANDFCOA_04289 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
IANDFCOA_04290 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IANDFCOA_04291 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IANDFCOA_04292 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
IANDFCOA_04293 8.66e-204 yybS - - S - - - membrane
IANDFCOA_04295 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
IANDFCOA_04296 1.3e-87 yybR - - K - - - Transcriptional regulator
IANDFCOA_04297 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
IANDFCOA_04298 3.67e-80 - - - - - - - -
IANDFCOA_04300 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IANDFCOA_04301 1.46e-140 - - - K - - - TipAS antibiotic-recognition domain
IANDFCOA_04302 2.05e-183 - - - - - - - -
IANDFCOA_04303 2.49e-87 - - - S - - - SnoaL-like domain
IANDFCOA_04304 5.67e-162 yybG - - S - - - Pentapeptide repeat-containing protein
IANDFCOA_04305 8.32e-275 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IANDFCOA_04306 1.31e-210 yybE - - K - - - Transcriptional regulator
IANDFCOA_04307 1.26e-100 yjcF - - S - - - Acetyltransferase (GNAT) domain
IANDFCOA_04308 1.94e-94 yybC - - - - - - -
IANDFCOA_04309 2.52e-163 - - - S - - - Metallo-beta-lactamase superfamily
IANDFCOA_04310 4.54e-100 yybA - - K - - - transcriptional
IANDFCOA_04311 2.85e-93 yjcF - - S - - - Acetyltransferase (GNAT) domain
IANDFCOA_04312 1.74e-124 yyaS - - S ko:K07149 - ko00000 Membrane
IANDFCOA_04313 1.84e-117 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
IANDFCOA_04314 1.5e-85 - - - S - - - YjbR
IANDFCOA_04315 8.62e-137 yyaP - - H - - - RibD C-terminal domain
IANDFCOA_04316 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
IANDFCOA_04317 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
IANDFCOA_04318 4.94e-214 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
IANDFCOA_04319 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
IANDFCOA_04320 1.55e-128 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
IANDFCOA_04321 9.85e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IANDFCOA_04322 1.29e-198 ccpB - - K - - - Transcriptional regulator
IANDFCOA_04323 4.68e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
IANDFCOA_04324 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IANDFCOA_04325 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IANDFCOA_04326 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
IANDFCOA_04327 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IANDFCOA_04328 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IANDFCOA_04329 7.41e-45 yyzM - - S - - - protein conserved in bacteria
IANDFCOA_04330 5.34e-227 yyaD - - S - - - Membrane
IANDFCOA_04331 1.3e-144 yyaC - - S - - - Sporulation protein YyaC
IANDFCOA_04332 1.32e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IANDFCOA_04333 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
IANDFCOA_04334 9.26e-98 - - - S - - - Bacterial PH domain
IANDFCOA_04335 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IANDFCOA_04336 5.86e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IANDFCOA_04337 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IANDFCOA_04338 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IANDFCOA_04339 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
IANDFCOA_04340 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IANDFCOA_04341 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)