ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
EHPLEFMO_00002 5.43e-97 - - - - - - - -
EHPLEFMO_00003 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
EHPLEFMO_00004 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
EHPLEFMO_00005 1.03e-150 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EHPLEFMO_00006 8.07e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHPLEFMO_00007 4.71e-169 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EHPLEFMO_00008 1.98e-39 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
EHPLEFMO_00009 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
EHPLEFMO_00010 9.2e-46 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
EHPLEFMO_00011 7.66e-116 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EHPLEFMO_00012 2.34e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHPLEFMO_00013 8.06e-156 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
EHPLEFMO_00014 1.03e-84 - - - - - - - -
EHPLEFMO_00015 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00017 1.46e-162 pnb - - C - - - nitroreductase
EHPLEFMO_00018 1.61e-07 - - - - - - - -
EHPLEFMO_00019 2.61e-251 - - - I - - - Protein of unknown function (DUF2974)
EHPLEFMO_00020 2.86e-64 - - - S - - - Protein of unknown function (DUF2974)
EHPLEFMO_00021 3.33e-140 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
EHPLEFMO_00022 1.83e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EHPLEFMO_00023 1.35e-300 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EHPLEFMO_00024 7.85e-285 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHPLEFMO_00025 2.69e-190 - - - - - - - -
EHPLEFMO_00026 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EHPLEFMO_00027 1.01e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EHPLEFMO_00028 7.29e-45 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
EHPLEFMO_00029 3.16e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
EHPLEFMO_00030 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
EHPLEFMO_00031 2.26e-118 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
EHPLEFMO_00032 1.53e-243 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
EHPLEFMO_00033 1.79e-106 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EHPLEFMO_00034 5.62e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
EHPLEFMO_00035 1.31e-70 ylbG - - S - - - UPF0298 protein
EHPLEFMO_00036 1.87e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EHPLEFMO_00037 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
EHPLEFMO_00038 8.33e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EHPLEFMO_00039 3.04e-48 ykzG - - S - - - Belongs to the UPF0356 family
EHPLEFMO_00040 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EHPLEFMO_00041 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
EHPLEFMO_00042 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EHPLEFMO_00043 8.69e-149 - - - S - - - repeat protein
EHPLEFMO_00044 7.5e-160 pgm - - G - - - Phosphoglycerate mutase family
EHPLEFMO_00045 3.28e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EHPLEFMO_00046 2.45e-75 XK27_04120 - - S - - - Putative amino acid metabolism
EHPLEFMO_00047 3.66e-274 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
EHPLEFMO_00048 1.56e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHPLEFMO_00049 3.72e-36 - - - - - - - -
EHPLEFMO_00050 3.66e-132 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
EHPLEFMO_00051 3.24e-44 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
EHPLEFMO_00052 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHPLEFMO_00053 1.14e-186 ylmH - - S - - - S4 domain protein
EHPLEFMO_00054 7.21e-62 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
EHPLEFMO_00055 3.21e-99 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EHPLEFMO_00056 2.86e-304 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EHPLEFMO_00057 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EHPLEFMO_00058 3.01e-190 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EHPLEFMO_00059 2.35e-266 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHPLEFMO_00060 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EHPLEFMO_00061 1.09e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHPLEFMO_00062 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EHPLEFMO_00063 1.14e-71 ftsL - - D - - - Cell division protein FtsL
EHPLEFMO_00064 3.78e-221 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EHPLEFMO_00065 4.45e-99 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
EHPLEFMO_00066 2.49e-73 - - - S - - - Protein of unknown function (DUF3397)
EHPLEFMO_00068 1.62e-123 mreD - - - ko:K03571 - ko00000,ko03036 -
EHPLEFMO_00069 7.59e-176 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
EHPLEFMO_00070 9.63e-225 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
EHPLEFMO_00071 3.2e-149 radC - - L ko:K03630 - ko00000 DNA repair protein
EHPLEFMO_00072 4.67e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
EHPLEFMO_00073 1.57e-299 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EHPLEFMO_00074 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EHPLEFMO_00075 2.38e-167 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EHPLEFMO_00076 9.32e-293 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHPLEFMO_00077 2.3e-276 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
EHPLEFMO_00078 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EHPLEFMO_00079 3.59e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EHPLEFMO_00080 4e-105 - - - S - - - Protein of unknown function (DUF1694)
EHPLEFMO_00081 5.39e-309 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
EHPLEFMO_00082 5.05e-57 - - - - - - - -
EHPLEFMO_00083 1.45e-102 uspA - - T - - - universal stress protein
EHPLEFMO_00084 2.41e-279 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
EHPLEFMO_00085 6.23e-47 - - - S - - - Protein of unknown function (DUF2969)
EHPLEFMO_00086 1.42e-60 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
EHPLEFMO_00087 5.61e-226 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
EHPLEFMO_00088 2.17e-43 - - - S - - - Protein of unknown function (DUF1146)
EHPLEFMO_00089 7.32e-95 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
EHPLEFMO_00090 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EHPLEFMO_00091 4.74e-218 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EHPLEFMO_00092 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EHPLEFMO_00093 2.9e-122 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHPLEFMO_00094 6.38e-102 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EHPLEFMO_00095 5.87e-38 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHPLEFMO_00096 9.32e-164 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
EHPLEFMO_00097 3.18e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EHPLEFMO_00098 9.18e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EHPLEFMO_00099 3.44e-200 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EHPLEFMO_00100 2.77e-249 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EHPLEFMO_00101 1.08e-145 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
EHPLEFMO_00102 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
EHPLEFMO_00103 3.69e-45 - - - - - - - -
EHPLEFMO_00104 4.22e-244 ampC - - V - - - Beta-lactamase
EHPLEFMO_00107 6.39e-227 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00108 1.04e-96 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00109 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
EHPLEFMO_00110 5.95e-147 vanZ - - V - - - VanZ like family
EHPLEFMO_00111 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EHPLEFMO_00112 0.0 yclK - - T - - - Histidine kinase
EHPLEFMO_00113 7.74e-173 - - - K - - - Transcriptional regulatory protein, C terminal
EHPLEFMO_00116 2.83e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHPLEFMO_00117 1.14e-231 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
EHPLEFMO_00120 2.03e-96 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
EHPLEFMO_00121 2.72e-67 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
EHPLEFMO_00122 1.43e-209 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
EHPLEFMO_00123 2.81e-232 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
EHPLEFMO_00124 1.01e-169 yebC - - K - - - Transcriptional regulatory protein
EHPLEFMO_00125 2.32e-121 - - - S - - - VanZ like family
EHPLEFMO_00126 1.93e-208 psaA - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EHPLEFMO_00127 3.8e-202 - - - S - - - Phospholipase, patatin family
EHPLEFMO_00128 4.18e-133 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHPLEFMO_00129 0.0 - - - E - - - Amino acid permease
EHPLEFMO_00130 1.78e-80 - - - GM - - - epimerase
EHPLEFMO_00131 5.29e-109 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHPLEFMO_00132 8.13e-85 - - - - - - - -
EHPLEFMO_00134 5.04e-293 - - - T - - - Diguanylate cyclase, GGDEF domain
EHPLEFMO_00135 1.06e-231 - - - T - - - Putative diguanylate phosphodiesterase
EHPLEFMO_00136 4e-189 - - - T - - - diguanylate cyclase activity
EHPLEFMO_00137 5.4e-147 - - - - - - - -
EHPLEFMO_00138 2.04e-79 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHPLEFMO_00139 2.7e-86 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHPLEFMO_00140 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
EHPLEFMO_00141 1.3e-82 - - - S - - - Cupredoxin-like domain
EHPLEFMO_00142 2.1e-99 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
EHPLEFMO_00143 2.59e-114 - - - V - - - Beta-lactamase
EHPLEFMO_00144 4.42e-73 - - - V - - - peptidase activity
EHPLEFMO_00145 1.06e-189 - - - S - - - hydrolase
EHPLEFMO_00146 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHPLEFMO_00147 2.25e-214 ybbR - - S - - - YbbR-like protein
EHPLEFMO_00148 6.34e-191 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EHPLEFMO_00149 1.71e-263 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHPLEFMO_00150 2.96e-174 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EHPLEFMO_00151 9.32e-184 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EHPLEFMO_00152 6.4e-260 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EHPLEFMO_00153 1.25e-206 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
EHPLEFMO_00154 5.46e-126 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EHPLEFMO_00155 1.13e-112 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
EHPLEFMO_00156 1.34e-233 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
EHPLEFMO_00157 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EHPLEFMO_00158 1.83e-202 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
EHPLEFMO_00159 4.43e-135 - - - - - - - -
EHPLEFMO_00160 2.39e-60 - - - K ko:K06977 - ko00000 acetyltransferase
EHPLEFMO_00161 2.01e-34 - - - K ko:K06977 - ko00000 acetyltransferase
EHPLEFMO_00162 1.83e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EHPLEFMO_00163 2.86e-286 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
EHPLEFMO_00164 1.42e-244 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EHPLEFMO_00165 4.59e-270 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
EHPLEFMO_00167 2.83e-47 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_00168 7.37e-72 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_00169 3.92e-122 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EHPLEFMO_00170 6.77e-38 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EHPLEFMO_00171 1.89e-13 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
EHPLEFMO_00172 4.12e-69 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
EHPLEFMO_00173 1.98e-40 ABC-SBP - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
EHPLEFMO_00174 0.0 - - - - - - - -
EHPLEFMO_00175 1.21e-130 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EHPLEFMO_00176 1.54e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
EHPLEFMO_00177 2.75e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
EHPLEFMO_00178 1.16e-209 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
EHPLEFMO_00179 4.16e-87 dmpA 3.4.11.19 - EQ ko:K01266 - ko00000,ko01000,ko01002 Peptidase family S58
EHPLEFMO_00180 3.72e-20 dmpA 3.4.11.19 - EQ ko:K01266 - ko00000,ko01000,ko01002 Peptidase family S58
EHPLEFMO_00181 5.05e-186 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
EHPLEFMO_00182 2.57e-116 - - - S - - - Short repeat of unknown function (DUF308)
EHPLEFMO_00183 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EHPLEFMO_00184 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EHPLEFMO_00185 2.48e-224 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EHPLEFMO_00186 1.36e-242 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
EHPLEFMO_00187 5.5e-200 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EHPLEFMO_00188 2.28e-223 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EHPLEFMO_00189 1.11e-56 - - - - - - - -
EHPLEFMO_00190 2.24e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EHPLEFMO_00191 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EHPLEFMO_00192 2.28e-126 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHPLEFMO_00193 2.7e-156 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
EHPLEFMO_00194 6.83e-312 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
EHPLEFMO_00195 2.7e-153 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
EHPLEFMO_00196 1.88e-273 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
EHPLEFMO_00197 1.65e-284 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
EHPLEFMO_00198 1.13e-252 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EHPLEFMO_00199 1.87e-126 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHPLEFMO_00200 1.63e-153 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
EHPLEFMO_00201 2.21e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
EHPLEFMO_00202 6.95e-301 ymfH - - S - - - Peptidase M16
EHPLEFMO_00203 3.8e-293 ymfF - - S - - - Peptidase M16 inactive domain protein
EHPLEFMO_00204 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EHPLEFMO_00205 1.81e-90 - - - S - - - Protein of unknown function (DUF1149)
EHPLEFMO_00206 2.21e-133 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EHPLEFMO_00207 5.85e-255 XK27_05220 - - S - - - AI-2E family transporter
EHPLEFMO_00208 7.79e-85 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
EHPLEFMO_00209 7.42e-88 - - - S - - - Virulence-associated protein E
EHPLEFMO_00212 5.67e-25 - - - - - - - -
EHPLEFMO_00215 1.19e-113 - - - L - - - Belongs to the 'phage' integrase family
EHPLEFMO_00216 2.89e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
EHPLEFMO_00217 3.66e-188 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EHPLEFMO_00218 2.21e-30 - - - - - - - -
EHPLEFMO_00219 8.2e-220 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EHPLEFMO_00220 7.48e-192 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHPLEFMO_00221 1.34e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
EHPLEFMO_00222 4.73e-140 - - - S - - - CYTH
EHPLEFMO_00223 6.36e-145 yjbH - - Q - - - Thioredoxin
EHPLEFMO_00224 1.17e-210 coiA - - S ko:K06198 - ko00000 Competence protein
EHPLEFMO_00225 1.5e-174 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EHPLEFMO_00226 3.22e-90 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EHPLEFMO_00227 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHPLEFMO_00228 6.14e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
EHPLEFMO_00230 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
EHPLEFMO_00231 4.54e-59 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
EHPLEFMO_00232 0.0 sufI - - Q - - - Multicopper oxidase
EHPLEFMO_00233 1.73e-36 - - - - - - - -
EHPLEFMO_00234 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EHPLEFMO_00235 1.07e-202 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
EHPLEFMO_00236 8.66e-96 - - - - - - - -
EHPLEFMO_00237 7.13e-110 - - - - - - - -
EHPLEFMO_00238 1.89e-188 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
EHPLEFMO_00239 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHPLEFMO_00240 3.03e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
EHPLEFMO_00242 3.93e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EHPLEFMO_00243 1.21e-212 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
EHPLEFMO_00244 3.34e-209 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
EHPLEFMO_00245 8.2e-102 ykuP - - C ko:K03839 - ko00000 Flavodoxin
EHPLEFMO_00246 1.01e-105 gtcA1 - - S - - - Teichoic acid glycosylation protein
EHPLEFMO_00247 1.95e-270 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EHPLEFMO_00248 7.82e-34 - - - - - - - -
EHPLEFMO_00249 0.0 - - - E - - - Amino acid permease
EHPLEFMO_00251 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
EHPLEFMO_00252 2.15e-299 ynbB - - P - - - aluminum resistance
EHPLEFMO_00253 3.14e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
EHPLEFMO_00254 3.02e-235 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
EHPLEFMO_00256 5.03e-312 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHPLEFMO_00257 6.18e-282 yfmL - - L - - - DEAD DEAH box helicase
EHPLEFMO_00258 4.48e-161 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
EHPLEFMO_00259 1.14e-292 - - - E ko:K03294 - ko00000 amino acid
EHPLEFMO_00260 3e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
EHPLEFMO_00261 0.0 yhdP - - S - - - Transporter associated domain
EHPLEFMO_00262 4.16e-31 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
EHPLEFMO_00264 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
EHPLEFMO_00265 3.82e-168 gntR - - K - - - UbiC transcription regulator-associated domain protein
EHPLEFMO_00266 2.57e-222 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
EHPLEFMO_00267 6.1e-160 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EHPLEFMO_00268 1.29e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
EHPLEFMO_00269 7.49e-208 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHPLEFMO_00270 1.6e-114 - - - - - - - -
EHPLEFMO_00272 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
EHPLEFMO_00273 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EHPLEFMO_00274 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
EHPLEFMO_00275 9.79e-196 - - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EHPLEFMO_00276 4.57e-142 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EHPLEFMO_00277 3.27e-142 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EHPLEFMO_00278 2.69e-192 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EHPLEFMO_00279 3.81e-171 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_00280 3.41e-151 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
EHPLEFMO_00281 5.48e-143 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
EHPLEFMO_00283 8.25e-131 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
EHPLEFMO_00284 2.34e-266 pepA - - E - - - M42 glutamyl aminopeptidase
EHPLEFMO_00285 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EHPLEFMO_00286 5.43e-183 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EHPLEFMO_00287 3.74e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
EHPLEFMO_00288 8.94e-272 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
EHPLEFMO_00289 3.64e-74 - - - - - - - -
EHPLEFMO_00291 3.3e-62 proP - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
EHPLEFMO_00292 3.15e-129 proP - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
EHPLEFMO_00293 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
EHPLEFMO_00294 6.17e-211 - - - S ko:K07088 - ko00000 Membrane transport protein
EHPLEFMO_00295 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EHPLEFMO_00296 4.27e-85 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
EHPLEFMO_00297 4.6e-10 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
EHPLEFMO_00298 1.55e-68 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional antiterminator
EHPLEFMO_00299 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EHPLEFMO_00300 3.25e-112 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
EHPLEFMO_00301 2.21e-69 - - - S ko:K08987 - ko00000 membrane
EHPLEFMO_00304 2.25e-10 - - - T - - - GGDEF domain
EHPLEFMO_00305 2.46e-134 - - - T - - - Gaf domain
EHPLEFMO_00306 8.2e-123 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NUDIX domain
EHPLEFMO_00307 2.83e-158 alkD - - L - - - DNA alkylation repair enzyme
EHPLEFMO_00308 2.09e-303 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EHPLEFMO_00309 1.82e-145 - - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
EHPLEFMO_00310 8.13e-62 - - - D - - - Di-iron-containing protein involved in the repair of iron-sulfur clusters
EHPLEFMO_00311 1.04e-45 copZ - - P - - - Heavy-metal-associated domain
EHPLEFMO_00312 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
EHPLEFMO_00314 1.93e-84 - - - C - - - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EHPLEFMO_00315 6.54e-111 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
EHPLEFMO_00316 8.8e-155 - 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
EHPLEFMO_00317 3.27e-172 - - - L ko:K07448 - ko00000,ko02048 Mrr N-terminal domain
EHPLEFMO_00318 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHPLEFMO_00319 9.1e-151 ybbB - - S - - - Protein of unknown function (DUF1211)
EHPLEFMO_00320 5.36e-218 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
EHPLEFMO_00321 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHPLEFMO_00322 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EHPLEFMO_00323 3.99e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHPLEFMO_00324 6.33e-256 camS - - S - - - sex pheromone
EHPLEFMO_00325 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHPLEFMO_00326 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
EHPLEFMO_00327 6.12e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
EHPLEFMO_00328 7.97e-131 - - - S - - - ECF transporter, substrate-specific component
EHPLEFMO_00330 2.99e-119 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
EHPLEFMO_00331 5.05e-38 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EHPLEFMO_00332 4.82e-92 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EHPLEFMO_00336 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
EHPLEFMO_00337 3.16e-194 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EHPLEFMO_00338 1.77e-174 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
EHPLEFMO_00339 3.56e-259 - - - M - - - Glycosyl transferases group 1
EHPLEFMO_00340 3.4e-173 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EHPLEFMO_00341 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
EHPLEFMO_00342 3.43e-284 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EHPLEFMO_00343 8.01e-162 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
EHPLEFMO_00344 1.33e-253 - - - - - - - -
EHPLEFMO_00345 2.66e-272 - - - - - - - -
EHPLEFMO_00346 6.21e-103 oppA2 - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00349 1.7e-222 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
EHPLEFMO_00350 2.44e-285 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EHPLEFMO_00353 1.8e-119 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
EHPLEFMO_00354 1.19e-74 - - - EGP - - - Major Facilitator
EHPLEFMO_00355 6.43e-66 - - - EGP - - - Major Facilitator
EHPLEFMO_00356 3.61e-154 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
EHPLEFMO_00357 7.9e-60 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00358 5.86e-44 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00359 9.75e-151 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00360 1.13e-37 - - - - - - - -
EHPLEFMO_00361 9.68e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
EHPLEFMO_00362 1.54e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EHPLEFMO_00363 8.77e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EHPLEFMO_00364 1.28e-183 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHPLEFMO_00365 2.44e-208 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHPLEFMO_00366 2.71e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHPLEFMO_00367 1.91e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
EHPLEFMO_00368 7.63e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHPLEFMO_00369 6.6e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EHPLEFMO_00370 5.08e-74 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EHPLEFMO_00371 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EHPLEFMO_00372 6.92e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EHPLEFMO_00373 5.33e-303 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EHPLEFMO_00374 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
EHPLEFMO_00375 1.1e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
EHPLEFMO_00376 4.52e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EHPLEFMO_00377 1.55e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EHPLEFMO_00378 2.92e-120 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EHPLEFMO_00379 9.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EHPLEFMO_00380 1.75e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EHPLEFMO_00381 5.64e-45 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EHPLEFMO_00382 1.73e-77 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EHPLEFMO_00383 1.34e-56 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EHPLEFMO_00384 9.34e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
EHPLEFMO_00385 8.89e-101 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EHPLEFMO_00386 3.28e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EHPLEFMO_00387 3.7e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EHPLEFMO_00388 1.79e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EHPLEFMO_00389 2.82e-198 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EHPLEFMO_00390 1.72e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EHPLEFMO_00391 6.65e-138 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
EHPLEFMO_00392 3.42e-142 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EHPLEFMO_00393 1.55e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
EHPLEFMO_00394 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHPLEFMO_00395 6.89e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EHPLEFMO_00396 2.96e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EHPLEFMO_00397 3.01e-11 - - - Q - - - phosphatase activity
EHPLEFMO_00398 1.83e-09 - - - S - - - hydrolase
EHPLEFMO_00400 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHPLEFMO_00401 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHPLEFMO_00404 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EHPLEFMO_00405 9.11e-106 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
EHPLEFMO_00409 3.88e-140 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
EHPLEFMO_00410 2.5e-278 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
EHPLEFMO_00411 2.42e-30 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 o-acetylhomoserine
EHPLEFMO_00413 2.21e-177 - - - T ko:K03320 - ko00000,ko02000 GGDEF domain
EHPLEFMO_00415 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
EHPLEFMO_00416 1.09e-251 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHPLEFMO_00417 0.0 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
EHPLEFMO_00418 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00419 2.85e-210 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EHPLEFMO_00420 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHPLEFMO_00421 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EHPLEFMO_00422 4.32e-80 - - - J ko:K07571 - ko00000 S1 RNA binding domain
EHPLEFMO_00423 4.01e-78 - - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
EHPLEFMO_00424 1.48e-45 yabO - - J - - - S4 domain protein
EHPLEFMO_00425 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EHPLEFMO_00426 5.2e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EHPLEFMO_00427 9.02e-163 - - - S - - - (CBS) domain
EHPLEFMO_00428 1.62e-276 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHPLEFMO_00429 3.58e-93 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EHPLEFMO_00430 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EHPLEFMO_00431 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EHPLEFMO_00432 3.27e-55 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
EHPLEFMO_00433 1.26e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHPLEFMO_00434 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EHPLEFMO_00435 3.45e-91 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EHPLEFMO_00436 1.34e-84 - - - S - - - Domain of unknown function (DUF1934)
EHPLEFMO_00437 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
EHPLEFMO_00438 5.18e-225 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EHPLEFMO_00439 3.49e-61 - - - - - - - -
EHPLEFMO_00440 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EHPLEFMO_00441 4.31e-192 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
EHPLEFMO_00442 4.13e-51 veg - - S - - - Biofilm formation stimulator VEG
EHPLEFMO_00443 9.09e-204 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EHPLEFMO_00444 3.34e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EHPLEFMO_00445 5.49e-191 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
EHPLEFMO_00446 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHPLEFMO_00447 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
EHPLEFMO_00448 7.13e-134 - - - S ko:K06872 - ko00000 TPM domain
EHPLEFMO_00449 2.79e-117 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
EHPLEFMO_00450 9.25e-247 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EHPLEFMO_00452 2.05e-154 - - - - - - - -
EHPLEFMO_00453 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHPLEFMO_00454 7.33e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EHPLEFMO_00455 7.19e-280 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EHPLEFMO_00456 2.12e-70 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
EHPLEFMO_00457 1.31e-213 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EHPLEFMO_00458 2.57e-78 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EHPLEFMO_00459 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EHPLEFMO_00460 1.45e-56 ylxQ - - J - - - ribosomal protein
EHPLEFMO_00461 1.03e-57 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
EHPLEFMO_00462 2.15e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
EHPLEFMO_00463 1.01e-109 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
EHPLEFMO_00464 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EHPLEFMO_00465 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EHPLEFMO_00466 5.13e-286 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
EHPLEFMO_00467 2.3e-186 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
EHPLEFMO_00468 3.99e-176 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EHPLEFMO_00469 2.75e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EHPLEFMO_00470 5.02e-169 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
EHPLEFMO_00471 3.29e-236 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EHPLEFMO_00472 1.49e-176 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
EHPLEFMO_00473 1.41e-243 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
EHPLEFMO_00474 2.26e-149 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
EHPLEFMO_00475 1.69e-231 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHPLEFMO_00476 9.32e-317 - 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EHPLEFMO_00477 2.28e-270 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
EHPLEFMO_00478 1.05e-93 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
EHPLEFMO_00479 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHPLEFMO_00480 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHPLEFMO_00481 1.55e-42 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
EHPLEFMO_00482 6.52e-43 ynzC - - S - - - UPF0291 protein
EHPLEFMO_00483 1.46e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHPLEFMO_00484 4.13e-193 - - - U ko:K05340 - ko00000,ko02000 ribose uptake protein RbsU
EHPLEFMO_00485 7.09e-193 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EHPLEFMO_00486 1.98e-123 - - - - - - - -
EHPLEFMO_00487 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
EHPLEFMO_00488 1.89e-316 - - - P - - - P-loop Domain of unknown function (DUF2791)
EHPLEFMO_00489 0.0 - - - S - - - TerB-C domain
EHPLEFMO_00490 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EHPLEFMO_00491 4.71e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EHPLEFMO_00492 0.0 snf - - KL - - - domain protein
EHPLEFMO_00495 1.39e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
EHPLEFMO_00496 4.06e-118 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EHPLEFMO_00497 3.93e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
EHPLEFMO_00498 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EHPLEFMO_00499 2.27e-71 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EHPLEFMO_00500 2.26e-95 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EHPLEFMO_00501 4.31e-115 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EHPLEFMO_00502 3.32e-20 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EHPLEFMO_00503 2.92e-207 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EHPLEFMO_00504 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
EHPLEFMO_00505 2.5e-164 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EHPLEFMO_00506 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EHPLEFMO_00507 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EHPLEFMO_00508 4.18e-208 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHPLEFMO_00509 4.46e-227 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EHPLEFMO_00510 3.53e-228 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHPLEFMO_00511 2.06e-139 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHPLEFMO_00512 2.89e-84 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHPLEFMO_00513 5.34e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHPLEFMO_00514 9.78e-232 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EHPLEFMO_00515 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EHPLEFMO_00516 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
EHPLEFMO_00517 1.67e-74 yloU - - S - - - Asp23 family, cell envelope-related function
EHPLEFMO_00518 3.26e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
EHPLEFMO_00519 0.0 - - - V - - - ABC transporter transmembrane region
EHPLEFMO_00522 6.14e-163 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
EHPLEFMO_00523 2.01e-212 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EHPLEFMO_00524 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
EHPLEFMO_00525 3.83e-178 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
EHPLEFMO_00526 2.21e-310 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHPLEFMO_00527 3e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHPLEFMO_00528 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHPLEFMO_00529 1.28e-45 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EHPLEFMO_00530 2.84e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
EHPLEFMO_00531 8.37e-66 - - - - - - - -
EHPLEFMO_00532 6.8e-46 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
EHPLEFMO_00533 1.2e-17 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00534 2.68e-49 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
EHPLEFMO_00535 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
EHPLEFMO_00536 5.49e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
EHPLEFMO_00537 1.16e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EHPLEFMO_00538 9.33e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EHPLEFMO_00539 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EHPLEFMO_00540 9.2e-198 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EHPLEFMO_00541 7.64e-88 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHPLEFMO_00542 6.3e-95 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
EHPLEFMO_00543 3.92e-131 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHPLEFMO_00544 3.27e-256 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
EHPLEFMO_00545 3.79e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
EHPLEFMO_00546 1.61e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
EHPLEFMO_00547 6.33e-87 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
EHPLEFMO_00548 1.29e-118 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
EHPLEFMO_00549 5.35e-76 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHPLEFMO_00550 4.58e-308 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
EHPLEFMO_00551 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
EHPLEFMO_00552 1.17e-141 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EHPLEFMO_00553 6.56e-251 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
EHPLEFMO_00554 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EHPLEFMO_00555 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHPLEFMO_00556 1.4e-162 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHPLEFMO_00557 8.7e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHPLEFMO_00558 5.04e-173 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
EHPLEFMO_00559 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EHPLEFMO_00560 9.21e-269 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EHPLEFMO_00561 6.03e-109 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EHPLEFMO_00562 1.66e-55 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
EHPLEFMO_00563 4.12e-275 - - - EGP - - - Major Facilitator Superfamily
EHPLEFMO_00564 1.11e-105 - - - - - - - -
EHPLEFMO_00565 1.52e-138 - - - - - - - -
EHPLEFMO_00566 0.0 - - - S - - - SH3-like domain
EHPLEFMO_00567 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
EHPLEFMO_00569 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EHPLEFMO_00570 1.64e-314 - - - EGP - - - Major Facilitator
EHPLEFMO_00571 3.72e-194 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
EHPLEFMO_00572 3.35e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EHPLEFMO_00573 3.79e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
EHPLEFMO_00574 9e-210 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
EHPLEFMO_00575 1.06e-83 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EHPLEFMO_00576 1.76e-161 - - - T - - - diguanylate cyclase
EHPLEFMO_00578 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
EHPLEFMO_00579 7.46e-50 - - - - - - - -
EHPLEFMO_00580 3.87e-168 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
EHPLEFMO_00581 1.87e-33 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHPLEFMO_00582 9.22e-204 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHPLEFMO_00583 7.23e-40 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHPLEFMO_00584 1.06e-180 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
EHPLEFMO_00585 1.71e-77 - - - KLT - - - serine threonine protein kinase
EHPLEFMO_00586 2.82e-153 - - - KLT - - - serine threonine protein kinase
EHPLEFMO_00587 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
EHPLEFMO_00588 2.26e-186 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
EHPLEFMO_00589 7.6e-118 ymdB - - S - - - Macro domain protein
EHPLEFMO_00590 1.67e-46 - - - - - - - -
EHPLEFMO_00591 4.25e-197 - - - - - - - -
EHPLEFMO_00593 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EHPLEFMO_00594 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
EHPLEFMO_00595 0.0 - - - M ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
EHPLEFMO_00596 6.78e-220 citI - - K - - - Putative sugar-binding domain
EHPLEFMO_00597 2.67e-49 lysM - - M - - - LysM domain
EHPLEFMO_00598 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
EHPLEFMO_00599 1.52e-63 ydgI - - C - - - Nitroreductase family
EHPLEFMO_00600 7.02e-288 - - - S - - - Putative peptidoglycan binding domain
EHPLEFMO_00601 2.83e-151 - - - - - - - -
EHPLEFMO_00602 7.19e-180 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
EHPLEFMO_00603 5.02e-22 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
EHPLEFMO_00604 4.9e-210 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
EHPLEFMO_00605 7.27e-112 - - - K - - - transcriptional regulator (TetR family)
EHPLEFMO_00606 1.44e-235 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
EHPLEFMO_00607 2.79e-153 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_00608 2.04e-168 - - - - - - - -
EHPLEFMO_00610 3.24e-138 - - - - - - - -
EHPLEFMO_00611 3.27e-150 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
EHPLEFMO_00613 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
EHPLEFMO_00614 4.76e-127 - - - K - - - WHG domain
EHPLEFMO_00615 1.19e-125 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
EHPLEFMO_00616 6.08e-125 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
EHPLEFMO_00617 2.05e-182 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
EHPLEFMO_00618 1.16e-238 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EHPLEFMO_00619 7.44e-113 cvpA - - S - - - Colicin V production protein
EHPLEFMO_00620 3.68e-170 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
EHPLEFMO_00621 3.12e-184 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EHPLEFMO_00622 2.37e-176 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
EHPLEFMO_00623 4.14e-200 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EHPLEFMO_00624 1.1e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
EHPLEFMO_00625 6.88e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EHPLEFMO_00626 3.8e-176 - - - S - - - Protein of unknown function (DUF1129)
EHPLEFMO_00627 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_00628 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
EHPLEFMO_00629 3.03e-159 vanR - - K - - - response regulator
EHPLEFMO_00630 4.19e-283 - - - T - - - His Kinase A (phosphoacceptor) domain
EHPLEFMO_00631 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHPLEFMO_00632 3.86e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
EHPLEFMO_00633 8.65e-174 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
EHPLEFMO_00634 1.41e-211 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EHPLEFMO_00635 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
EHPLEFMO_00636 5.86e-185 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
EHPLEFMO_00637 1.7e-155 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EHPLEFMO_00638 2.09e-173 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
EHPLEFMO_00639 1.46e-112 - - - KT - - - response to antibiotic
EHPLEFMO_00640 3.03e-92 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
EHPLEFMO_00641 2.45e-29 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
EHPLEFMO_00642 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
EHPLEFMO_00643 3.2e-264 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
EHPLEFMO_00645 0.0 - - - S - - - ABC transporter, ATP-binding protein
EHPLEFMO_00646 4.59e-173 - - - S - - - Putative threonine/serine exporter
EHPLEFMO_00647 1.27e-110 - - - S - - - Threonine/Serine exporter, ThrE
EHPLEFMO_00648 1.96e-102 - - - - - - - -
EHPLEFMO_00649 4.02e-145 - - - - - - - -
EHPLEFMO_00650 0.0 - - - S - - - O-antigen ligase like membrane protein
EHPLEFMO_00651 2.89e-64 - - - - - - - -
EHPLEFMO_00652 6.35e-126 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
EHPLEFMO_00653 2.11e-108 lytE - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family
EHPLEFMO_00654 1.09e-253 idhA 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHPLEFMO_00655 2.91e-104 lytE - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
EHPLEFMO_00656 2.47e-158 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
EHPLEFMO_00657 1.83e-86 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
EHPLEFMO_00658 9.23e-53 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
EHPLEFMO_00659 3.6e-117 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
EHPLEFMO_00660 5.22e-160 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
EHPLEFMO_00661 2.04e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EHPLEFMO_00662 1.74e-103 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
EHPLEFMO_00663 2.15e-109 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
EHPLEFMO_00664 2.89e-157 epsB - - M - - - biosynthesis protein
EHPLEFMO_00665 3.47e-151 ywqD - - D - - - Capsular exopolysaccharide family
EHPLEFMO_00666 6.92e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
EHPLEFMO_00667 4e-155 epsE2 - - M - - - Bacterial sugar transferase
EHPLEFMO_00668 3.58e-108 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
EHPLEFMO_00669 4.5e-89 - - GT2 S ko:K12992 ko02025,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyltransferase like family 2
EHPLEFMO_00670 2.26e-99 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
EHPLEFMO_00671 4.41e-85 - - - GM - - - GDP-mannose 4,6 dehydratase
EHPLEFMO_00672 2.41e-75 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase, family 2
EHPLEFMO_00674 1.43e-47 - - - M - - - Glycosyltransferase family 92
EHPLEFMO_00675 2.56e-07 - - - M - - - Glycosyltransferase like family 2
EHPLEFMO_00676 0.0 XK27_08315 - - M - - - Sulfatase
EHPLEFMO_00677 6.93e-140 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EHPLEFMO_00678 9.16e-272 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
EHPLEFMO_00679 2.71e-167 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EHPLEFMO_00680 2.38e-171 - - - - - - - -
EHPLEFMO_00681 6.4e-118 - - - S - - - Oxidoreductase
EHPLEFMO_00682 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
EHPLEFMO_00683 0.0 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
EHPLEFMO_00684 1.24e-228 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EHPLEFMO_00685 3.68e-45 - - - S - - - Protein of unknown function (DUF2922)
EHPLEFMO_00686 3.54e-39 - - - - - - - -
EHPLEFMO_00687 2.18e-177 - - - - - - - -
EHPLEFMO_00688 3.17e-94 - - - - - - - -
EHPLEFMO_00689 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
EHPLEFMO_00690 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
EHPLEFMO_00691 2.18e-82 - - - O - - - Glutaredoxin-related protein
EHPLEFMO_00692 1.18e-291 yqjV - - EGP - - - Major Facilitator Superfamily
EHPLEFMO_00693 7.14e-52 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
EHPLEFMO_00694 6.18e-44 yitW - - S - - - Iron-sulfur cluster assembly protein
EHPLEFMO_00695 7.21e-182 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHPLEFMO_00696 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
EHPLEFMO_00697 5.46e-315 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
EHPLEFMO_00698 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EHPLEFMO_00699 0.0 - - - S - - - Calcineurin-like phosphoesterase
EHPLEFMO_00700 3e-108 - - - - - - - -
EHPLEFMO_00701 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00702 9.06e-191 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHPLEFMO_00703 1.59e-173 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHPLEFMO_00704 2.39e-179 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EHPLEFMO_00705 1.99e-211 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
EHPLEFMO_00706 2.22e-108 usp5 - - T - - - universal stress protein
EHPLEFMO_00707 3.05e-191 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
EHPLEFMO_00708 8.99e-109 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EHPLEFMO_00709 2.59e-116 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
EHPLEFMO_00710 7.2e-283 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
EHPLEFMO_00711 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
EHPLEFMO_00712 2.65e-186 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EHPLEFMO_00713 5.02e-128 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHPLEFMO_00714 4.53e-127 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
EHPLEFMO_00715 4.6e-218 - - - I - - - alpha/beta hydrolase fold
EHPLEFMO_00716 1.14e-165 yibF - - S - - - overlaps another CDS with the same product name
EHPLEFMO_00717 6.42e-243 yibE - - S - - - overlaps another CDS with the same product name
EHPLEFMO_00719 1.41e-263 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
EHPLEFMO_00720 8.83e-264 - - - S - - - Cysteine-rich secretory protein family
EHPLEFMO_00721 9.8e-150 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
EHPLEFMO_00722 7.92e-184 - - - - - - - -
EHPLEFMO_00723 2.31e-162 - - - K - - - Bacterial regulatory proteins, tetR family
EHPLEFMO_00724 2.95e-237 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EHPLEFMO_00725 1.92e-162 - - - S - - - Alpha/beta hydrolase family
EHPLEFMO_00726 2.85e-205 epsV - - S - - - glycosyl transferase family 2
EHPLEFMO_00727 8.04e-209 - - - S - - - Protein of unknown function (DUF1002)
EHPLEFMO_00728 2.48e-176 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHPLEFMO_00729 1.28e-228 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
EHPLEFMO_00730 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHPLEFMO_00731 1.43e-105 - - - - - - - -
EHPLEFMO_00732 3.56e-169 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
EHPLEFMO_00733 7.87e-88 yeaO - - S - - - Protein of unknown function, DUF488
EHPLEFMO_00734 6.22e-158 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
EHPLEFMO_00735 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
EHPLEFMO_00736 2.81e-181 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_00737 1.4e-153 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
EHPLEFMO_00738 2.78e-222 - - - L - - - HNH nucleases
EHPLEFMO_00739 1.37e-21 - - - - - - - -
EHPLEFMO_00740 1.46e-261 ysdE - - P - - - Citrate transporter
EHPLEFMO_00741 1.67e-123 lemA - - S ko:K03744 - ko00000 LemA family
EHPLEFMO_00742 2.94e-206 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
EHPLEFMO_00743 3.42e-195 mutR - - K - - - Helix-turn-helix XRE-family like proteins
EHPLEFMO_00744 4.84e-284 - - - S ko:K09136 - ko00000,ko03009 ATP diphosphatase activity
EHPLEFMO_00746 1.61e-176 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
EHPLEFMO_00747 2.22e-155 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
EHPLEFMO_00748 9.27e-220 - - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EHPLEFMO_00749 6.12e-195 - - - K - - - helix_turn_helix, arabinose operon control protein
EHPLEFMO_00750 0.0 qacA - - EGP - - - Major Facilitator
EHPLEFMO_00751 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_00752 1.49e-147 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
EHPLEFMO_00753 8.58e-90 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
EHPLEFMO_00754 1.09e-77 - - - - - - - -
EHPLEFMO_00755 6.37e-76 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
EHPLEFMO_00756 1.31e-123 - - - M - - - ErfK YbiS YcfS YnhG
EHPLEFMO_00757 9.99e-216 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
EHPLEFMO_00758 7.86e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EHPLEFMO_00759 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EHPLEFMO_00760 1.29e-72 yheA - - S - - - Belongs to the UPF0342 family
EHPLEFMO_00761 8.89e-289 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
EHPLEFMO_00762 0.0 yhaN - - L - - - AAA domain
EHPLEFMO_00763 1.28e-229 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
EHPLEFMO_00764 3.25e-89 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 - F ko:K00014,ko:K00891,ko:K03785,ko:K03786,ko:K13829,ko:K15546 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko03000 shikimate kinase activity
EHPLEFMO_00765 1.27e-64 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EHPLEFMO_00766 1.67e-198 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EHPLEFMO_00767 9.14e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EHPLEFMO_00768 2.5e-173 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EHPLEFMO_00769 3.21e-215 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EHPLEFMO_00770 2.32e-70 - - - - - - - -
EHPLEFMO_00771 1.67e-104 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
EHPLEFMO_00772 1.23e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_00773 3.82e-276 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
EHPLEFMO_00774 6.67e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EHPLEFMO_00775 9.52e-72 ytpP - - CO - - - Thioredoxin
EHPLEFMO_00776 4.88e-154 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EHPLEFMO_00777 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
EHPLEFMO_00778 4.76e-27 - - - K - - - Transcriptional regulator
EHPLEFMO_00779 1.44e-49 - - - EGP - - - Major facilitator Superfamily
EHPLEFMO_00780 1.4e-107 - - - EGP - - - Major Facilitator
EHPLEFMO_00781 6.48e-60 - - - EGP - - - Major Facilitator
EHPLEFMO_00782 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHPLEFMO_00783 1.2e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EHPLEFMO_00784 1.03e-131 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EHPLEFMO_00785 1.57e-107 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EHPLEFMO_00786 5.47e-314 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
EHPLEFMO_00787 1.7e-212 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
EHPLEFMO_00788 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHPLEFMO_00789 2.88e-114 - - - S ko:K06921 - ko00000 Archaea bacterial proteins of unknown function
EHPLEFMO_00790 0.0 - - - L - - - Putative transposase DNA-binding domain
EHPLEFMO_00791 3.99e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EHPLEFMO_00792 1.37e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
EHPLEFMO_00793 2.91e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EHPLEFMO_00794 1.16e-270 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
EHPLEFMO_00795 1.58e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EHPLEFMO_00796 6.76e-143 yqeK - - H - - - Hydrolase, HD family
EHPLEFMO_00797 1.46e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EHPLEFMO_00798 6.53e-271 ylbM - - S - - - Belongs to the UPF0348 family
EHPLEFMO_00799 6e-130 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
EHPLEFMO_00800 1.96e-164 csrR - - K - - - response regulator
EHPLEFMO_00801 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHPLEFMO_00802 3.9e-201 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EHPLEFMO_00803 5.39e-61 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
EHPLEFMO_00804 1.09e-174 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHPLEFMO_00805 9.83e-81 yodB - - K - - - Transcriptional regulator, HxlR family
EHPLEFMO_00806 8.32e-254 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EHPLEFMO_00807 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EHPLEFMO_00808 2.55e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EHPLEFMO_00809 0.0 - - - S - - - membrane
EHPLEFMO_00810 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EHPLEFMO_00811 2.18e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EHPLEFMO_00812 2.26e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EHPLEFMO_00813 3.24e-147 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
EHPLEFMO_00814 2.98e-45 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
EHPLEFMO_00815 8.9e-92 yqhL - - P - - - Rhodanese-like protein
EHPLEFMO_00816 1.87e-218 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EHPLEFMO_00817 2.56e-207 ynbB - - P - - - aluminum resistance
EHPLEFMO_00818 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
EHPLEFMO_00819 1.76e-277 - - - EGP - - - Major Facilitator Superfamily
EHPLEFMO_00820 5.13e-84 - - - S - - - Domain of unknown function DUF1828
EHPLEFMO_00821 1.31e-79 - - - - - - - -
EHPLEFMO_00822 7.81e-238 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHPLEFMO_00823 8.26e-92 - - - E - - - Methionine synthase
EHPLEFMO_00824 9.42e-288 - - - EK - - - Aminotransferase, class I
EHPLEFMO_00825 3.61e-214 yvbU - - K - - - LysR substrate binding domain
EHPLEFMO_00826 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
EHPLEFMO_00827 6.58e-101 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EHPLEFMO_00828 2.34e-283 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EHPLEFMO_00829 4.29e-41 - - - S ko:K07045 - ko00000 Amidohydrolase
EHPLEFMO_00830 5.38e-222 gyaR 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHPLEFMO_00831 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
EHPLEFMO_00832 4.16e-233 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
EHPLEFMO_00833 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EHPLEFMO_00834 6.47e-298 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EHPLEFMO_00835 0.0 oatA - - I - - - Acyltransferase
EHPLEFMO_00836 1.33e-223 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EHPLEFMO_00837 2.99e-177 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EHPLEFMO_00838 1.11e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
EHPLEFMO_00839 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EHPLEFMO_00840 0.0 - - - L - - - SNF2 family N-terminal domain
EHPLEFMO_00841 5.63e-45 - - - - - - - -
EHPLEFMO_00843 1.6e-127 ywlG - - S - - - Belongs to the UPF0340 family
EHPLEFMO_00844 1.01e-19 - - - K ko:K03492 - ko00000,ko03000 UTRA
EHPLEFMO_00845 7.99e-73 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
EHPLEFMO_00846 6.82e-116 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHPLEFMO_00847 2.87e-39 - - - S - - - Protein of unknown function (DUF2929)
EHPLEFMO_00848 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
EHPLEFMO_00849 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EHPLEFMO_00850 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
EHPLEFMO_00851 2.01e-51 ssuB - - P ko:K02049,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 anion transmembrane transporter activity
EHPLEFMO_00853 4.38e-209 yitL - - S ko:K00243 - ko00000 S1 domain
EHPLEFMO_00854 8.85e-212 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
EHPLEFMO_00855 2.22e-82 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHPLEFMO_00856 4.59e-164 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EHPLEFMO_00857 7.53e-137 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EHPLEFMO_00858 4.13e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EHPLEFMO_00859 1.58e-148 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EHPLEFMO_00860 5.23e-06 mltD - - M ko:K08307 - ko00000,ko01000,ko01011 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EHPLEFMO_00861 1.22e-139 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
EHPLEFMO_00862 2.15e-280 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
EHPLEFMO_00863 4.47e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
EHPLEFMO_00864 3.22e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EHPLEFMO_00865 1.68e-292 XK27_05225 - - S - - - Tetratricopeptide repeat protein
EHPLEFMO_00866 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
EHPLEFMO_00867 2.87e-219 - - - K - - - LysR substrate binding domain
EHPLEFMO_00868 4.27e-146 - - - K ko:K13928 - ko00000,ko03000 DNA-binding transcription factor activity
EHPLEFMO_00869 2.61e-35 - - - - - - - -
EHPLEFMO_00870 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHPLEFMO_00871 5.36e-93 - - - - - - - -
EHPLEFMO_00872 3.05e-18 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
EHPLEFMO_00876 0.0 cas3 - - L ko:K07012 - ko00000,ko01000,ko02048 CRISPR-associated helicase cas3
EHPLEFMO_00877 0.0 casA - - L ko:K19123 - ko00000,ko02048 the current gene model (or a revised gene model) may contain a frame shift
EHPLEFMO_00878 4.72e-141 - - - S ko:K19046 - ko00000,ko02048 CRISPR-associated protein Cse2 (CRISPR_cse2)
EHPLEFMO_00879 6.88e-237 casC - - L ko:K19124 - ko00000,ko02048 CT1975-like protein
EHPLEFMO_00880 7.76e-169 casD - - S ko:K19125 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
EHPLEFMO_00881 4.2e-151 casE - - S ko:K19126 - ko00000,ko02048 CRISPR_assoc
EHPLEFMO_00882 1.02e-214 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EHPLEFMO_00883 1.83e-200 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas2CT1978)
EHPLEFMO_00884 1.51e-183 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
EHPLEFMO_00885 3.72e-203 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EHPLEFMO_00886 2.21e-72 yabA - - L - - - Involved in initiation control of chromosome replication
EHPLEFMO_00887 5.96e-206 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EHPLEFMO_00888 1.83e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
EHPLEFMO_00889 2.32e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EHPLEFMO_00890 2.21e-46 - - - S - - - Protein of unknown function (DUF2508)
EHPLEFMO_00891 1.03e-138 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EHPLEFMO_00892 1.9e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EHPLEFMO_00893 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EHPLEFMO_00894 2.25e-116 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EHPLEFMO_00895 4.22e-143 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
EHPLEFMO_00896 2.31e-117 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EHPLEFMO_00897 2.35e-167 - - - - - - - -
EHPLEFMO_00898 5.5e-26 - - - - - - - -
EHPLEFMO_00899 3.19e-59 - - - - - - - -
EHPLEFMO_00900 9.36e-20 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
EHPLEFMO_00901 7.54e-264 pbpX1 - - V - - - Beta-lactamase
EHPLEFMO_00902 9.67e-273 pbpX - - V - - - Beta-lactamase
EHPLEFMO_00903 1.49e-54 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EHPLEFMO_00904 1.58e-15 - 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose/Galactose Isomerase
EHPLEFMO_00905 1.84e-27 - 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose/Galactose Isomerase
EHPLEFMO_00906 1.22e-15 rpiB2 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose/Galactose Isomerase
EHPLEFMO_00908 5.39e-111 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EHPLEFMO_00909 9.22e-18 - - - P - - - nitric oxide dioxygenase activity
EHPLEFMO_00910 2.1e-190 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00911 8.54e-109 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00912 1.42e-71 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EHPLEFMO_00913 1.35e-108 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EHPLEFMO_00914 1.83e-174 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
EHPLEFMO_00915 1.7e-108 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
EHPLEFMO_00916 5.15e-91 - - - - - - - -
EHPLEFMO_00917 4.64e-294 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
EHPLEFMO_00918 4.22e-244 - - - S - - - Glycosyl transferase family 2
EHPLEFMO_00919 4.45e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EHPLEFMO_00920 3.27e-91 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EHPLEFMO_00921 5.63e-131 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
EHPLEFMO_00922 3.07e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EHPLEFMO_00923 7.32e-28 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EHPLEFMO_00924 4.55e-161 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHPLEFMO_00925 1.92e-116 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHPLEFMO_00926 3.17e-149 - - - S - - - Alpha/beta hydrolase family
EHPLEFMO_00927 3.19e-45 - - - - - - - -
EHPLEFMO_00928 5.81e-131 - - - K ko:K03091 - ko00000,ko03021 sigma factor activity
EHPLEFMO_00929 1.34e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHPLEFMO_00930 6.26e-101 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EHPLEFMO_00931 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EHPLEFMO_00932 6.07e-137 - - - F - - - NUDIX domain
EHPLEFMO_00933 3.19e-206 - - - K - - - LysR substrate binding domain
EHPLEFMO_00934 9.35e-231 - - - S - - - Conserved hypothetical protein 698
EHPLEFMO_00935 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHPLEFMO_00937 6.54e-156 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
EHPLEFMO_00938 6.26e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
EHPLEFMO_00939 2.07e-08 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00940 1.72e-139 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00941 7.74e-180 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_00942 1.84e-122 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EHPLEFMO_00943 5.25e-295 - - - F - - - Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EHPLEFMO_00944 6.69e-228 - 6.3.4.18, 6.3.5.5 - F ko:K01589,ko:K01955,ko:K16181 ko00230,ko00240,ko00250,ko00300,ko01100,ko01110,ko01120,ko01130,map00230,map00240,map00250,map00300,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 5-(carboxyamino)imidazole ribonucleotide synthase activity
EHPLEFMO_00945 1.32e-31 - 6.3.4.18, 6.3.5.5 - F ko:K01589,ko:K01955,ko:K16181 ko00230,ko00240,ko00250,ko00300,ko01100,ko01110,ko01120,ko01130,map00230,map00240,map00250,map00300,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 5-(carboxyamino)imidazole ribonucleotide synthase activity
EHPLEFMO_00946 6.7e-205 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EHPLEFMO_00947 4.16e-215 - - - - - - - -
EHPLEFMO_00948 7.55e-96 ydjH 2.7.1.15 - G ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHPLEFMO_00949 2.89e-273 - - - EGP - - - Transmembrane secretion effector
EHPLEFMO_00950 4.78e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
EHPLEFMO_00951 1.71e-95 - - - T - - - diguanylate cyclase
EHPLEFMO_00952 2.74e-24 - - - T - - - diguanylate cyclase
EHPLEFMO_00954 5.87e-56 - - - T - - - EAL domain
EHPLEFMO_00955 3.6e-70 - - - T - - - EAL domain
EHPLEFMO_00956 9.89e-15 - - - T - - - diguanylate cyclase
EHPLEFMO_00957 1.03e-111 - - - S - - - ECF-type riboflavin transporter, S component
EHPLEFMO_00958 0.0 - 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
EHPLEFMO_00959 2.03e-185 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
EHPLEFMO_00960 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_00961 3.5e-126 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
EHPLEFMO_00962 2.33e-202 XK27_10120 - - K - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
EHPLEFMO_00963 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
EHPLEFMO_00964 0.0 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-type transport system involved in multi-copper enzyme maturation permease component
EHPLEFMO_00965 1.27e-217 potA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EHPLEFMO_00966 5.97e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
EHPLEFMO_00968 1.53e-116 - - - T - - - Putative diguanylate phosphodiesterase
EHPLEFMO_00969 1.63e-114 - - - T - - - Putative diguanylate phosphodiesterase
EHPLEFMO_00970 3.3e-236 - - - M - - - Glycosyl transferase family 8
EHPLEFMO_00971 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EHPLEFMO_00972 1.09e-128 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
EHPLEFMO_00973 7.39e-65 - - - - - - - -
EHPLEFMO_00974 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
EHPLEFMO_00976 4.68e-234 - - - S - - - AAA domain
EHPLEFMO_00977 8.76e-104 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EHPLEFMO_00978 9.79e-159 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EHPLEFMO_00979 8.57e-41 - - - - - - - -
EHPLEFMO_00980 2.88e-39 - - - - - - - -
EHPLEFMO_00981 5.92e-165 - - - G - - - Belongs to the phosphoglycerate mutase family
EHPLEFMO_00982 8.14e-62 - - - S ko:K07090 - ko00000 membrane transporter protein
EHPLEFMO_00983 2.4e-58 - - - S ko:K07090 - ko00000 membrane transporter protein
EHPLEFMO_00984 2.77e-140 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
EHPLEFMO_00985 1.58e-122 - - - K - - - Acetyltransferase (GNAT) family
EHPLEFMO_00986 5.83e-251 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EHPLEFMO_00987 1.65e-49 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase
EHPLEFMO_00988 9.02e-177 - - - K - - - Helix-turn-helix domain, rpiR family
EHPLEFMO_00989 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
EHPLEFMO_00990 3.7e-39 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
EHPLEFMO_00991 1.7e-213 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
EHPLEFMO_00992 3.01e-11 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
EHPLEFMO_00993 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
EHPLEFMO_00994 5.96e-189 - - - D - - - nuclear chromosome segregation
EHPLEFMO_00995 1.03e-122 - - - M - - - LysM domain protein
EHPLEFMO_00997 3.72e-203 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EHPLEFMO_00998 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
EHPLEFMO_01002 1.7e-128 - 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
EHPLEFMO_01003 5.31e-136 yiiE - - S - - - Protein of unknown function (DUF1211)
EHPLEFMO_01004 1.07e-32 - - - - - - - -
EHPLEFMO_01005 5.09e-93 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
EHPLEFMO_01006 4.27e-75 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
EHPLEFMO_01007 5.24e-70 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
EHPLEFMO_01008 1.31e-101 - 2.7.1.211 - G ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
EHPLEFMO_01009 9.39e-256 - 2.7.1.11, 2.7.1.90 - F ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EHPLEFMO_01010 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EHPLEFMO_01011 6.32e-97 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
EHPLEFMO_01012 6.4e-77 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
EHPLEFMO_01013 2.42e-57 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
EHPLEFMO_01014 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
EHPLEFMO_01015 0.0 - - - E - - - Amino acid permease
EHPLEFMO_01016 8.47e-148 - - - L - - - Transposase and inactivated derivatives, IS30 family
EHPLEFMO_01017 9.63e-260 - - - G - - - Major Facilitator Superfamily
EHPLEFMO_01018 3.21e-48 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
EHPLEFMO_01019 6.3e-263 - - - G - - - Major Facilitator Superfamily
EHPLEFMO_01020 1.32e-69 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
EHPLEFMO_01021 1.21e-169 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
EHPLEFMO_01023 6.93e-89 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
EHPLEFMO_01024 1.2e-126 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
EHPLEFMO_01025 2.09e-25 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
EHPLEFMO_01026 3.6e-284 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
EHPLEFMO_01029 3.39e-63 - - - - - - - -
EHPLEFMO_01030 0.0 - - - L - - - Helicase conserved C-terminal domain
EHPLEFMO_01031 4.74e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
EHPLEFMO_01032 4.15e-10 - - - K - - - Helix-turn-helix domain
EHPLEFMO_01034 2.01e-208 - 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
EHPLEFMO_01035 2.81e-313 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
EHPLEFMO_01036 3.77e-08 - - - - - - - -
EHPLEFMO_01037 1.64e-83 - - - S - - - Domain of unknown function (DUF956)
EHPLEFMO_01038 2.27e-217 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
EHPLEFMO_01039 8.56e-180 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
EHPLEFMO_01040 1.16e-239 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
EHPLEFMO_01042 5.94e-08 secY2 - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 SecY translocase
EHPLEFMO_01043 1.04e-288 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EHPLEFMO_01044 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EHPLEFMO_01047 3.25e-223 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
EHPLEFMO_01048 1.06e-312 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EHPLEFMO_01049 7.14e-117 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EHPLEFMO_01050 2.35e-210 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
EHPLEFMO_01051 9.47e-317 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EHPLEFMO_01052 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHPLEFMO_01053 8.75e-198 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
EHPLEFMO_01054 6.57e-177 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHPLEFMO_01055 4.39e-210 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EHPLEFMO_01056 9.85e-49 yozE - - S - - - Belongs to the UPF0346 family
EHPLEFMO_01057 5.28e-200 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
EHPLEFMO_01058 5.65e-151 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
EHPLEFMO_01059 1.02e-280 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EHPLEFMO_01060 1.04e-215 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHPLEFMO_01065 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
EHPLEFMO_01066 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_01067 1.79e-212 - - - K - - - LysR substrate binding domain
EHPLEFMO_01068 6.72e-204 - - - - - - - -
EHPLEFMO_01069 1.52e-129 - - - I - - - PAP2 superfamily
EHPLEFMO_01070 1.06e-193 - - - S - - - Uncharacterised protein, DegV family COG1307
EHPLEFMO_01071 9.3e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EHPLEFMO_01072 6.21e-68 - - - S - - - Protein of unknown function (DUF2752)
EHPLEFMO_01074 1.37e-211 - - - S - - - Bacterial protein of unknown function (DUF898)
EHPLEFMO_01075 5.93e-135 - - - S - - - Protein of unknown function (DUF4230)
EHPLEFMO_01076 1.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_01077 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
EHPLEFMO_01078 5.83e-188 lysR5 - - K - - - LysR substrate binding domain
EHPLEFMO_01079 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
EHPLEFMO_01080 2.73e-142 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
EHPLEFMO_01081 8.77e-245 - - - S - - - AI-2E family transporter
EHPLEFMO_01082 1.39e-257 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EHPLEFMO_01083 3.83e-200 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
EHPLEFMO_01084 5.47e-66 - - - K - - - DNA-binding transcription factor activity
EHPLEFMO_01085 2.82e-122 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHPLEFMO_01086 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
EHPLEFMO_01087 2.32e-149 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
EHPLEFMO_01088 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EHPLEFMO_01089 5.57e-237 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EHPLEFMO_01090 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
EHPLEFMO_01091 1.04e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EHPLEFMO_01092 1.79e-243 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EHPLEFMO_01093 1.9e-227 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
EHPLEFMO_01094 1.52e-73 - - - L - - - Belongs to the 'phage' integrase family
EHPLEFMO_01095 3.45e-25 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
EHPLEFMO_01096 3.43e-74 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EHPLEFMO_01097 8.74e-260 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
EHPLEFMO_01098 1.87e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EHPLEFMO_01099 7.12e-256 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
EHPLEFMO_01100 4.67e-127 - 3.6.1.67 - F ko:K19965 ko00790,map00790 ko00000,ko00001,ko00002,ko01000 NUDIX domain
EHPLEFMO_01101 9.53e-21 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
EHPLEFMO_01102 1.32e-144 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
EHPLEFMO_01103 5.65e-121 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
EHPLEFMO_01104 8.35e-175 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_01105 2.53e-205 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
EHPLEFMO_01107 7.93e-309 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHPLEFMO_01109 1.17e-79 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
EHPLEFMO_01110 9.84e-295 amd - - E - - - Peptidase family M20/M25/M40
EHPLEFMO_01111 5.67e-20 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
EHPLEFMO_01112 3.18e-155 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
EHPLEFMO_01113 9.42e-30 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_01114 1.76e-77 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_01115 2.11e-220 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_01116 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_01117 7.38e-42 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
EHPLEFMO_01118 7.95e-142 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_01119 1.1e-139 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_01120 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHPLEFMO_01121 9.35e-202 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHPLEFMO_01122 3.19e-239 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHPLEFMO_01123 2.78e-251 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHPLEFMO_01124 7.7e-227 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EHPLEFMO_01125 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
EHPLEFMO_01126 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Papain family cysteine protease
EHPLEFMO_01127 9.76e-93 - - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EHPLEFMO_01128 5.07e-103 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EHPLEFMO_01129 3.88e-316 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EHPLEFMO_01130 3.46e-241 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EHPLEFMO_01131 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
EHPLEFMO_01132 6.71e-85 - - - - - - - -
EHPLEFMO_01133 3.79e-291 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
EHPLEFMO_01134 1.6e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EHPLEFMO_01135 2.95e-263 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EHPLEFMO_01136 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
EHPLEFMO_01137 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
EHPLEFMO_01138 2.54e-68 - - - K - - - Transcriptional regulator
EHPLEFMO_01139 2.99e-94 - - - K - - - Transcriptional regulator
EHPLEFMO_01140 6.84e-200 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHPLEFMO_01141 1.86e-146 - - - F - - - Phosphorylase superfamily
EHPLEFMO_01142 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
EHPLEFMO_01143 2.43e-216 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
EHPLEFMO_01144 9.96e-25 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHPLEFMO_01145 1.69e-197 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EHPLEFMO_01146 2.28e-220 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
EHPLEFMO_01147 1.26e-101 - - - S - - - Aminoacyl-tRNA editing domain
EHPLEFMO_01148 0.000129 pheA 4.2.1.51, 5.4.99.5 - E ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
EHPLEFMO_01149 1.65e-97 - - - K - - - DNA-binding transcription factor activity
EHPLEFMO_01150 2.51e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
EHPLEFMO_01151 1.34e-09 - - - Q - - - phosphatase activity
EHPLEFMO_01152 1.85e-120 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
EHPLEFMO_01153 1.28e-103 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EHPLEFMO_01154 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EHPLEFMO_01155 8.84e-37 - - - K - - - LysR substrate binding domain
EHPLEFMO_01156 1.28e-56 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction
EHPLEFMO_01157 4.07e-216 - - - L - - - Belongs to the 'phage' integrase family
EHPLEFMO_01158 1.65e-106 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
EHPLEFMO_01159 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
EHPLEFMO_01160 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
EHPLEFMO_01161 5.13e-102 - - - GM - - - NmrA-like family
EHPLEFMO_01162 5.39e-23 - - - S - - - Domain of unknown function (DUF4343)
EHPLEFMO_01163 1.81e-99 - - - S ko:K07126 - ko00000 Sel1-like repeats.
EHPLEFMO_01164 1.79e-266 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
EHPLEFMO_01165 1.72e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
EHPLEFMO_01166 3.99e-76 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
EHPLEFMO_01167 1.06e-132 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
EHPLEFMO_01169 2.48e-77 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
EHPLEFMO_01170 4.69e-115 yfhC - - C - - - Nitroreductase family
EHPLEFMO_01171 7.72e-38 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
EHPLEFMO_01172 4.71e-148 pgm1 - - G - - - phosphoglycerate mutase
EHPLEFMO_01173 8.07e-51 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EHPLEFMO_01174 8.73e-142 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EHPLEFMO_01175 5.64e-113 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHPLEFMO_01176 2.23e-149 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHPLEFMO_01177 6.46e-212 - - - EG - - - EamA-like transporter family
EHPLEFMO_01178 5.28e-240 - - - - - - - -
EHPLEFMO_01179 8.41e-203 - - - S - - - EDD domain protein, DegV family
EHPLEFMO_01180 0.0 FbpA - - K - - - Fibronectin-binding protein
EHPLEFMO_01181 1.39e-313 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
EHPLEFMO_01182 4.02e-58 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
EHPLEFMO_01183 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
EHPLEFMO_01184 1.88e-251 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EHPLEFMO_01185 1.95e-218 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EHPLEFMO_01186 1.3e-99 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EHPLEFMO_01187 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
EHPLEFMO_01188 1.28e-77 - - - - - - - -
EHPLEFMO_01189 1.93e-84 XK27_01810 - - S - - - Calcineurin-like phosphoesterase
EHPLEFMO_01190 2.72e-134 XK27_01810 - - S - - - Calcineurin-like phosphoesterase
EHPLEFMO_01191 1.01e-278 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
EHPLEFMO_01192 5.35e-85 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EHPLEFMO_01193 8.99e-138 ypsA - - S - - - Belongs to the UPF0398 family
EHPLEFMO_01194 6.44e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EHPLEFMO_01195 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
EHPLEFMO_01196 0.0 yuxL 3.4.19.1 - E ko:K01303 - ko00000,ko01000,ko01002 Prolyl oligopeptidase family
EHPLEFMO_01197 6.48e-243 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHPLEFMO_01198 1.33e-77 - - - I - - - acetylesterase activity
EHPLEFMO_01199 5.21e-91 - - - I - - - Psort location Cytoplasmic, score
EHPLEFMO_01200 4.33e-192 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
EHPLEFMO_01201 4.71e-149 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EHPLEFMO_01202 1.24e-147 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
EHPLEFMO_01203 1.9e-92 ypmB - - S - - - Protein conserved in bacteria
EHPLEFMO_01204 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
EHPLEFMO_01205 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
EHPLEFMO_01206 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
EHPLEFMO_01207 2.02e-215 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
EHPLEFMO_01208 1.22e-224 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
EHPLEFMO_01209 4.5e-259 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
EHPLEFMO_01210 6.51e-247 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EHPLEFMO_01211 8.23e-219 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
EHPLEFMO_01212 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EHPLEFMO_01213 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EHPLEFMO_01214 1.56e-144 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EHPLEFMO_01215 1.56e-38 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
EHPLEFMO_01216 9.79e-233 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
EHPLEFMO_01217 3.35e-53 - - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
EHPLEFMO_01218 2.16e-46 - - - V ko:K06147 - ko00000,ko02000 (ABC) transporter
EHPLEFMO_01219 1.6e-12 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EHPLEFMO_01220 2.61e-193 - - - G - - - Sucrose-6F-phosphate phosphohydrolase
EHPLEFMO_01221 9.98e-134 - - - - - - - -
EHPLEFMO_01222 2.53e-240 - - - T - - - diguanylate cyclase
EHPLEFMO_01223 1.92e-262 - - - T - - - Putative diguanylate phosphodiesterase
EHPLEFMO_01224 7.65e-67 - - - T - - - Putative diguanylate phosphodiesterase
EHPLEFMO_01226 1.43e-135 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
EHPLEFMO_01227 1.17e-171 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
EHPLEFMO_01228 4.3e-190 - - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EHPLEFMO_01229 1.28e-178 - - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EHPLEFMO_01230 2.01e-129 - - - S - - - C4-dicarboxylate anaerobic carrier
EHPLEFMO_01231 3.14e-132 M1-740 - - I - - - NUDIX domain
EHPLEFMO_01232 3.26e-162 - - - S - - - Glycosyl hydrolases family 18
EHPLEFMO_01233 2.23e-51 - - - S - - - Glycosyl hydrolases family 18
EHPLEFMO_01234 3.17e-156 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
EHPLEFMO_01236 6.08e-83 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
EHPLEFMO_01237 2.86e-05 - - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 pfam abc
EHPLEFMO_01238 2.99e-12 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
EHPLEFMO_01239 2.71e-28 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
EHPLEFMO_01240 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHPLEFMO_01241 2.5e-161 phoB - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
EHPLEFMO_01242 1.98e-147 - - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
EHPLEFMO_01243 9.06e-182 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EHPLEFMO_01244 4.17e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
EHPLEFMO_01245 5.27e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
EHPLEFMO_01246 8.71e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
EHPLEFMO_01249 7.51e-75 - - - T - - - Putative diguanylate phosphodiesterase
EHPLEFMO_01250 1e-35 - - - - - - - -
EHPLEFMO_01251 1.27e-113 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_01252 9.33e-38 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_01253 5.97e-72 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
EHPLEFMO_01254 4.9e-207 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHPLEFMO_01256 9.31e-193 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EHPLEFMO_01257 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
EHPLEFMO_01258 5.57e-219 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
EHPLEFMO_01259 2.52e-129 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EHPLEFMO_01260 4.68e-99 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EHPLEFMO_01261 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EHPLEFMO_01262 4.29e-174 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
EHPLEFMO_01263 2.21e-228 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
EHPLEFMO_01264 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
EHPLEFMO_01265 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EHPLEFMO_01266 3.67e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EHPLEFMO_01267 1.38e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EHPLEFMO_01268 1.83e-258 - - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHPLEFMO_01269 1.22e-26 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EHPLEFMO_01270 2.64e-50 celA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 beta-glucosidase activity
EHPLEFMO_01271 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
EHPLEFMO_01272 2.21e-124 mdt(A) - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Major facilitator Superfamily
EHPLEFMO_01273 7.99e-110 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
EHPLEFMO_01274 1.19e-32 - - - - - - - -
EHPLEFMO_01275 5.87e-221 - - - S - - - Protein of unknown function DUF262
EHPLEFMO_01277 4.53e-34 - - - K - - - Cro/C1-type HTH DNA-binding domain
EHPLEFMO_01278 0.0 - 2.1.1.72 - L ko:K03427 - ko00000,ko01000,ko02048 N-6 DNA methylase
EHPLEFMO_01279 2.61e-168 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
EHPLEFMO_01280 0.0 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Type III restriction
EHPLEFMO_01281 0.0 - - - S - - - Protein of unknown function (DUF1524)
EHPLEFMO_01282 8.73e-37 - - - K - - - Helix-turn-helix domain
EHPLEFMO_01283 6.54e-144 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
EHPLEFMO_01284 9.96e-65 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
EHPLEFMO_01285 1.08e-38 adaA1 2.1.1.63, 3.2.2.21 - K ko:K10778,ko:K13529,ko:K13530,ko:K15051 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 sequence-specific DNA binding
EHPLEFMO_01286 1.13e-165 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHPLEFMO_01287 9.59e-180 - - - S - - - Peptidase family M23
EHPLEFMO_01288 7.34e-104 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
EHPLEFMO_01289 1.13e-155 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
EHPLEFMO_01290 3.18e-193 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EHPLEFMO_01291 4.76e-310 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
EHPLEFMO_01292 3.04e-32 - - - - - - - -
EHPLEFMO_01293 1.37e-133 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EHPLEFMO_01294 4.73e-206 - - - L - - - Phage integrase, N-terminal SAM-like domain
EHPLEFMO_01295 6.29e-71 - - - S - - - Alpha beta hydrolase
EHPLEFMO_01297 8.95e-17 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
EHPLEFMO_01298 5.84e-253 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
EHPLEFMO_01299 4.98e-131 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
EHPLEFMO_01300 1.95e-97 - - - - - - - -
EHPLEFMO_01301 9.92e-104 - - - K - - - GNAT family
EHPLEFMO_01302 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EHPLEFMO_01303 3.89e-185 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
EHPLEFMO_01304 3.2e-212 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Peptidase family M48
EHPLEFMO_01305 1.4e-119 - - - GM - - - NmrA-like family
EHPLEFMO_01306 4.87e-101 ywnA - - K - - - Transcriptional regulator
EHPLEFMO_01307 2.02e-217 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_01308 0.0 - - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EHPLEFMO_01309 0.0 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EHPLEFMO_01310 9.3e-26 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EHPLEFMO_01311 1.73e-24 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
EHPLEFMO_01312 2.46e-93 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
EHPLEFMO_01313 5.87e-177 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
EHPLEFMO_01314 9.55e-146 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EHPLEFMO_01315 4.3e-36 - - - - - - - -
EHPLEFMO_01316 1.5e-177 - - - - - - - -
EHPLEFMO_01317 8.58e-223 - - - - - - - -
EHPLEFMO_01318 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
EHPLEFMO_01319 6.42e-201 - - - V - - - LD-carboxypeptidase
EHPLEFMO_01321 4.98e-12 - - - D - - - Filamentation induced by cAMP protein fic
EHPLEFMO_01322 2.52e-95 - - - C - - - FMN_bind
EHPLEFMO_01323 3.65e-139 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
EHPLEFMO_01325 2.13e-169 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
EHPLEFMO_01326 5.97e-56 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
EHPLEFMO_01327 9.18e-09 - - - S - - - Bacterial membrane protein YfhO
EHPLEFMO_01330 1.88e-49 - - - S - - - Protein conserved in bacteria
EHPLEFMO_01334 9.99e-41 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
EHPLEFMO_01335 2.68e-67 XK27_05625 - - P - - - Rhodanese Homology Domain
EHPLEFMO_01336 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
EHPLEFMO_01337 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_01338 2.41e-101 - - - K - - - Transcriptional regulator, MarR family
EHPLEFMO_01339 3.25e-223 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHPLEFMO_01340 0.0 - - - - - - - -
EHPLEFMO_01341 0.0 - - - - - - - -
EHPLEFMO_01342 1.86e-08 - - - Q - - - Methyltransferase domain
EHPLEFMO_01343 1.98e-234 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
EHPLEFMO_01344 1.9e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
EHPLEFMO_01345 4.03e-137 - - - S - - - Protein of unknown function (DUF1461)
EHPLEFMO_01346 4.49e-184 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EHPLEFMO_01347 3.37e-117 yutD - - S - - - Protein of unknown function (DUF1027)
EHPLEFMO_01348 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EHPLEFMO_01349 2.89e-77 - - - - - - - -
EHPLEFMO_01350 2.14e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
EHPLEFMO_01351 6.81e-274 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
EHPLEFMO_01352 4.86e-59 - - - - - - - -
EHPLEFMO_01353 1.1e-27 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EHPLEFMO_01354 5.67e-196 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
EHPLEFMO_01355 1.78e-147 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EHPLEFMO_01356 1.01e-87 yslB - - S - - - Protein of unknown function (DUF2507)
EHPLEFMO_01357 3.11e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EHPLEFMO_01358 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EHPLEFMO_01359 1.92e-67 yrzB - - S - - - Belongs to the UPF0473 family
EHPLEFMO_01360 6.34e-94 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EHPLEFMO_01361 3.09e-56 yrzL - - S - - - Belongs to the UPF0297 family
EHPLEFMO_01362 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHPLEFMO_01363 5e-294 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EHPLEFMO_01364 1.89e-228 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
EHPLEFMO_01365 4.7e-262 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHPLEFMO_01366 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EHPLEFMO_01367 1.21e-70 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
EHPLEFMO_01368 1.02e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EHPLEFMO_01369 4.05e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EHPLEFMO_01370 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EHPLEFMO_01371 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EHPLEFMO_01372 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EHPLEFMO_01373 3.69e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHPLEFMO_01374 2.3e-158 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EHPLEFMO_01375 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
EHPLEFMO_01376 1.43e-248 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EHPLEFMO_01377 1.51e-122 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
EHPLEFMO_01378 5.82e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
EHPLEFMO_01379 1.57e-51 - - - S - - - ECF transporter, substrate-specific component
EHPLEFMO_01380 5.35e-81 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
EHPLEFMO_01385 8.64e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EHPLEFMO_01386 3.7e-239 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
EHPLEFMO_01387 6.41e-193 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
EHPLEFMO_01388 2.67e-181 yycI - - S - - - YycH protein
EHPLEFMO_01389 3.35e-313 yycH - - S - - - YycH protein
EHPLEFMO_01390 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EHPLEFMO_01391 1.09e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
EHPLEFMO_01393 5.29e-193 - - - I - - - Acyl-transferase
EHPLEFMO_01394 1.03e-198 arbx - - M - - - Glycosyl transferase family 8
EHPLEFMO_01395 2.33e-122 - - - M - - - Glycosyl transferase family 8
EHPLEFMO_01396 8.87e-211 arbZ - - I - - - Phosphate acyltransferases
EHPLEFMO_01397 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
EHPLEFMO_01398 6.6e-92 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
EHPLEFMO_01399 1.22e-221 - - - K - - - Transcriptional regulator, LysR family
EHPLEFMO_01400 8.09e-95 - - - EGP - - - Major Facilitator Superfamily
EHPLEFMO_01401 4.75e-57 - - - EGP - - - Major Facilitator Superfamily
EHPLEFMO_01402 3.15e-126 - - - S - - - Membrane
EHPLEFMO_01403 2.73e-282 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
EHPLEFMO_01404 4.37e-212 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
EHPLEFMO_01405 5.37e-220 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
EHPLEFMO_01407 9.53e-138 - - - - - - - -
EHPLEFMO_01408 1.88e-274 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
EHPLEFMO_01409 3.9e-16 cpsY - - K - - - Transcriptional regulator, LysR family
EHPLEFMO_01410 6.39e-166 cpsY - - K - - - Transcriptional regulator, LysR family
EHPLEFMO_01411 1.06e-166 - - - - - - - -
EHPLEFMO_01412 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EHPLEFMO_01413 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
EHPLEFMO_01414 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
EHPLEFMO_01415 1.35e-286 - 1.3.8.1, 1.3.8.7 - I ko:K00248,ko:K00249,ko:K18244 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 ko00000,ko00001,ko00002,ko01000 Acyl-CoA dehydrogenase, C-terminal domain
EHPLEFMO_01416 1.82e-09 - - - S - - - PD-(D/E)XK nuclease family transposase
EHPLEFMO_01417 3.02e-08 - - - S - - - PD-(D/E)XK nuclease family transposase
EHPLEFMO_01418 3.74e-148 - - - T - - - Region found in RelA / SpoT proteins
EHPLEFMO_01419 9.36e-151 dltr - - K - - - response regulator
EHPLEFMO_01420 1.61e-291 sptS - - T - - - Histidine kinase
EHPLEFMO_01421 2.36e-248 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EHPLEFMO_01422 5.93e-278 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
EHPLEFMO_01423 6.16e-282 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
EHPLEFMO_01424 1.89e-309 - - - S - - - Putative threonine/serine exporter
EHPLEFMO_01425 1.16e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EHPLEFMO_01426 7.96e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
EHPLEFMO_01427 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHPLEFMO_01428 2.42e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EHPLEFMO_01429 5e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
EHPLEFMO_01430 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EHPLEFMO_01431 3.27e-46 - - - - - - - -
EHPLEFMO_01432 0.0 - - - S - - - Predicted membrane protein (DUF2207)
EHPLEFMO_01433 1.05e-235 ydbI - - K - - - AI-2E family transporter
EHPLEFMO_01434 4.78e-222 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHPLEFMO_01435 1.31e-44 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHPLEFMO_01436 2.22e-229 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
EHPLEFMO_01437 1.53e-158 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
EHPLEFMO_01438 3.77e-288 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EHPLEFMO_01439 1.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EHPLEFMO_01440 6.26e-101 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EHPLEFMO_01441 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
EHPLEFMO_01442 2.63e-205 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHPLEFMO_01443 7.4e-178 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
EHPLEFMO_01444 1.05e-162 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
EHPLEFMO_01445 1.39e-156 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EHPLEFMO_01447 1.95e-64 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
EHPLEFMO_01448 4.09e-11 - 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
EHPLEFMO_01450 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EHPLEFMO_01451 4.32e-91 - - - - - - - -
EHPLEFMO_01452 2.56e-20 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
EHPLEFMO_01453 0.0 eriC - - P ko:K03281 - ko00000 chloride
EHPLEFMO_01454 1.89e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
EHPLEFMO_01455 8.7e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_01456 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHPLEFMO_01457 8.05e-166 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
EHPLEFMO_01458 6.66e-159 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
EHPLEFMO_01459 1.98e-51 - - - - - - - -
EHPLEFMO_01460 2.05e-177 ybfG - - M - - - peptidoglycan-binding domain-containing protein
EHPLEFMO_01462 3.02e-19 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
EHPLEFMO_01464 1.05e-162 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EHPLEFMO_01465 1.78e-202 - - - S - - - Aldo/keto reductase family
EHPLEFMO_01467 1.46e-25 - - - EGP - - - Major Facilitator
EHPLEFMO_01468 2.1e-220 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EHPLEFMO_01469 3.73e-263 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EHPLEFMO_01470 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
EHPLEFMO_01471 7.4e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
EHPLEFMO_01472 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
EHPLEFMO_01473 2.52e-241 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHPLEFMO_01474 6.2e-242 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHPLEFMO_01475 3.91e-245 potA11 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K02052,ko:K11072 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EHPLEFMO_01476 1.73e-175 potC3 - - E ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHPLEFMO_01477 1.93e-179 - - - E ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EHPLEFMO_01478 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EHPLEFMO_01479 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EHPLEFMO_01480 9.01e-196 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EHPLEFMO_01481 1.48e-82 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EHPLEFMO_01482 1.7e-313 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHPLEFMO_01483 1.62e-255 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EHPLEFMO_01484 2.22e-50 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
EHPLEFMO_01485 1.36e-266 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EHPLEFMO_01486 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHPLEFMO_01487 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHPLEFMO_01488 1.21e-63 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
EHPLEFMO_01489 1.79e-126 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EHPLEFMO_01490 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EHPLEFMO_01491 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
EHPLEFMO_01492 6.68e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
EHPLEFMO_01493 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
EHPLEFMO_01494 6.23e-290 - - - S - - - Protein of unknown function (DUF2974)
EHPLEFMO_01495 0.0 - - - V - - - ATPases associated with a variety of cellular activities
EHPLEFMO_01496 4.46e-90 - - - - - - - -
EHPLEFMO_01498 4.6e-157 - - - S ko:K07507 - ko00000,ko02000 MgtC family
EHPLEFMO_01499 1.61e-36 - - - - - - - -
EHPLEFMO_01501 4.92e-204 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
EHPLEFMO_01502 1.14e-123 - - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_01503 5.88e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
EHPLEFMO_01504 1.07e-241 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EHPLEFMO_01505 2.35e-150 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EHPLEFMO_01506 2.39e-198 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EHPLEFMO_01507 1.11e-265 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EHPLEFMO_01508 1.73e-253 - - - KQ - - - Hypothetical methyltransferase
EHPLEFMO_01509 4.88e-98 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
EHPLEFMO_01510 1.32e-85 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
EHPLEFMO_01511 5.85e-15 - - - - - - - -
EHPLEFMO_01512 1.34e-198 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
EHPLEFMO_01513 1.45e-140 - - - L - - - nuclease
EHPLEFMO_01514 1.31e-17 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
EHPLEFMO_01515 3.34e-300 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
EHPLEFMO_01516 1.06e-203 - - - K - - - LysR substrate binding domain
EHPLEFMO_01517 3.39e-48 - - - K - - - SIR2-like domain
EHPLEFMO_01518 1.11e-102 - - - K - - - SIR2-like domain
EHPLEFMO_01519 1.1e-68 - - - L ko:K07484 - ko00000 IS66 Orf2 like protein
EHPLEFMO_01520 1.08e-27 - - - - - - - -
EHPLEFMO_01521 2.33e-292 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
EHPLEFMO_01522 7.7e-279 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
EHPLEFMO_01523 3.58e-70 - - - M - - - Psort location Cytoplasmic, score
EHPLEFMO_01524 3.66e-120 ybaJ - - Q - - - Hypothetical methyltransferase
EHPLEFMO_01525 6.26e-46 - - - V ko:K06147 - ko00000,ko02000 (ABC) transporter
EHPLEFMO_01526 0.0 carB - - F - - - Psort location Cytoplasmic, score 8.87
EHPLEFMO_01527 1.85e-125 carB - - F - - - Psort location Cytoplasmic, score 8.87
EHPLEFMO_01528 2.06e-198 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EHPLEFMO_01529 7.14e-24 carA 6.3.5.5 - F ko:K01955,ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EHPLEFMO_01530 1.38e-49 - - - T - - - diguanylate cyclase activity
EHPLEFMO_01531 7.07e-275 - - - V - - - drug transmembrane transporter activity
EHPLEFMO_01532 1.01e-95 - - - K - - - 3.5.2 Transcription regulation
EHPLEFMO_01533 1.64e-95 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
EHPLEFMO_01534 1.22e-136 - - - L - - - Integrase
EHPLEFMO_01535 6.86e-25 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EHPLEFMO_01536 3.65e-15 cylB - - U ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
EHPLEFMO_01537 6.13e-100 - - - S - - - Psort location CytoplasmicMembrane, score
EHPLEFMO_01538 1.11e-97 - - - - - - - -
EHPLEFMO_01539 4.97e-93 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphotyrosine protein phosphatase
EHPLEFMO_01540 2.02e-168 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_01541 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
EHPLEFMO_01542 5.11e-18 - - - C - - - Pyridoxamine 5'-phosphate oxidase
EHPLEFMO_01544 4.26e-108 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
EHPLEFMO_01545 3.29e-244 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
EHPLEFMO_01546 3.3e-56 - - - K - - - Protein of unknown function (DUF4065)
EHPLEFMO_01547 7.28e-47 - - - K - - - Protein of unknown function (DUF4065)
EHPLEFMO_01550 8e-136 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
EHPLEFMO_01551 1.6e-115 - - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin transmembrane transporter activity
EHPLEFMO_01552 7.18e-57 - - - - - - - -
EHPLEFMO_01553 9.96e-154 - - - - - - - -
EHPLEFMO_01554 2.49e-16 - - - - - - - -
EHPLEFMO_01555 1.92e-161 pgm7 - - G - - - Phosphoglycerate mutase family
EHPLEFMO_01556 3.76e-134 - - - E - - - GDSL-like Lipase/Acylhydrolase
EHPLEFMO_01557 1.62e-133 - - - T - - - EAL domain
EHPLEFMO_01558 1.02e-195 yitS - - S - - - EDD domain protein, DegV family
EHPLEFMO_01559 2.68e-111 - - - K - - - Domain of unknown function (DUF1836)
EHPLEFMO_01560 6.42e-229 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 Glycosyltransferase like family 2
EHPLEFMO_01561 0.0 - - - S - - - Bacterial membrane protein, YfhO
EHPLEFMO_01562 1.41e-205 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
EHPLEFMO_01563 1.19e-171 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
EHPLEFMO_01564 1.81e-109 - - - K - - - DNA-templated transcription, initiation
EHPLEFMO_01566 2.79e-177 - - - - - - - -
EHPLEFMO_01568 3.6e-38 scrK 2.7.1.2, 2.7.1.4 - GK ko:K00845,ko:K00847 ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
EHPLEFMO_01569 6.73e-244 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EHPLEFMO_01570 1.1e-35 bgl 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 beta-glucosidase activity
EHPLEFMO_01572 1.66e-42 bgl 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 beta-glucosidase activity
EHPLEFMO_01574 1.09e-178 - - - L - - - Transposase
EHPLEFMO_01576 4.45e-98 cydD1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
EHPLEFMO_01577 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
EHPLEFMO_01578 1.26e-95 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
EHPLEFMO_01579 1.26e-285 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHPLEFMO_01580 2.93e-280 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
EHPLEFMO_01581 1.14e-183 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
EHPLEFMO_01582 9.11e-118 yjcF - - S - - - Acetyltransferase (GNAT) domain
EHPLEFMO_01583 1.48e-49 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
EHPLEFMO_01584 3.69e-93 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
EHPLEFMO_01586 3.12e-151 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_01587 3.68e-277 - - - S - - - FtsX-like permease family
EHPLEFMO_01590 5.92e-102 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EHPLEFMO_01591 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EHPLEFMO_01592 1.3e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
EHPLEFMO_01593 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EHPLEFMO_01594 6.29e-227 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EHPLEFMO_01595 1.06e-256 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
EHPLEFMO_01596 1.63e-278 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
EHPLEFMO_01597 8.37e-96 - - - S - - - VanZ like family
EHPLEFMO_01598 3.27e-96 gtcA - - S - - - Teichoic acid glycosylation protein
EHPLEFMO_01599 6.85e-164 - - - S - - - VanZ like family
EHPLEFMO_01600 8.37e-75 - - - L - - - DNA synthesis involved in DNA repair
EHPLEFMO_01601 4.87e-115 - - - L - - - DNA synthesis involved in DNA repair
EHPLEFMO_01603 2.33e-11 - 3.1.4.46, 3.2.1.99 GH43 N ko:K01126,ko:K06113 ko00564,map00564 ko00000,ko00001,ko01000 domain, Protein
EHPLEFMO_01605 2.72e-48 - - - - - - - -
EHPLEFMO_01606 1.35e-172 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EHPLEFMO_01607 1.58e-160 gpm2 - - G - - - Phosphoglycerate mutase family
EHPLEFMO_01608 2.58e-147 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
EHPLEFMO_01609 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EHPLEFMO_01610 2.71e-107 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
EHPLEFMO_01612 8.21e-97 - - - K - - - LytTr DNA-binding domain
EHPLEFMO_01613 4.26e-133 - - - E - - - GDSL-like Lipase/Acylhydrolase
EHPLEFMO_01614 1.01e-220 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
EHPLEFMO_01615 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHPLEFMO_01616 1.82e-101 - - - S - - - Helix-turn-helix domain
EHPLEFMO_01617 1.24e-230 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
EHPLEFMO_01618 3.13e-252 - - - - - - - -
EHPLEFMO_01619 0.0 - - - V - - - ABC transporter transmembrane region
EHPLEFMO_01620 2.39e-12 - - - S - - - PAS domain
EHPLEFMO_01621 2.48e-62 - - - GK - - - ROK family
EHPLEFMO_01622 8.92e-34 - - - GK - - - ROK family
EHPLEFMO_01624 1.46e-199 dkgB - - S - - - reductase
EHPLEFMO_01625 2.59e-175 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
EHPLEFMO_01626 6.86e-56 - - - E ko:K08659 - ko00000,ko01000,ko01002 dipeptidase activity
EHPLEFMO_01627 2.09e-136 - - - - - - - -
EHPLEFMO_01628 6.64e-113 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
EHPLEFMO_01629 1.49e-222 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
EHPLEFMO_01630 1.7e-208 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
EHPLEFMO_01631 1.69e-203 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
EHPLEFMO_01632 2.2e-36 - - - - - - - -
EHPLEFMO_01633 9.52e-128 yobS - - K - - - Bacterial regulatory proteins, tetR family
EHPLEFMO_01634 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
EHPLEFMO_01635 1.58e-228 - - - - - - - -
EHPLEFMO_01637 3.62e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
EHPLEFMO_01638 3.18e-67 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
EHPLEFMO_01639 6.01e-45 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 epimerase
EHPLEFMO_01640 1.09e-77 ywnA - - K - - - Transcriptional regulator
EHPLEFMO_01641 1.55e-109 - - - S - - - YcxB-like protein
EHPLEFMO_01642 2.18e-132 - - - T - - - integral membrane protein
EHPLEFMO_01643 0.0 - - - L - - - Helicase C-terminal domain protein
EHPLEFMO_01644 1.59e-117 - - - S - - - ECF-type riboflavin transporter, S component
EHPLEFMO_01645 2.06e-195 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
EHPLEFMO_01646 8.13e-38 - - - K - - - Acetyltransferase (GNAT) domain
EHPLEFMO_01647 0.0 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
EHPLEFMO_01649 4.4e-170 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
EHPLEFMO_01650 2.7e-145 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_01652 1.59e-266 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
EHPLEFMO_01653 5.15e-223 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
EHPLEFMO_01654 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
EHPLEFMO_01655 1.67e-274 - - - M - - - Glycosyl transferases group 1
EHPLEFMO_01657 1.38e-62 - - - L - - - Winged helix-turn helix
EHPLEFMO_01658 7.24e-106 - - - L - - - DDE superfamily endonuclease
EHPLEFMO_01659 1.49e-187 cps3J - - M - - - Domain of unknown function (DUF4422)
EHPLEFMO_01660 3.5e-224 - - - S - - - Glycosyltransferase like family 2
EHPLEFMO_01661 4.9e-239 - - - M - - - Glycosyl transferase family 2
EHPLEFMO_01662 9.55e-285 cps3F - - - - - - -
EHPLEFMO_01663 2.55e-222 - - - M - - - Glycosyltransferase like family 2
EHPLEFMO_01664 2.74e-242 cps2G - - M - - - Stealth protein CR2, conserved region 2
EHPLEFMO_01665 8.87e-247 - - - S - - - Acyltransferase family
EHPLEFMO_01666 1.89e-73 - - - S - - - Psort location CytoplasmicMembrane, score
EHPLEFMO_01667 9.94e-79 - - - S - - - Psort location CytoplasmicMembrane, score
EHPLEFMO_01668 2.1e-138 - - - S - - - Psort location CytoplasmicMembrane, score
EHPLEFMO_01669 2.8e-33 - - - L - - - PFAM Transposase
EHPLEFMO_01670 9.11e-126 - - - S - - - SLAP domain
EHPLEFMO_01671 1.13e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
EHPLEFMO_01672 4.45e-96 - - - S - - - Domain of unknown function (DUF4352)
EHPLEFMO_01673 1.64e-238 pkn2 - - KLT - - - Protein tyrosine kinase
EHPLEFMO_01674 1.35e-85 - - - S - - - Psort location Cytoplasmic, score
EHPLEFMO_01676 1e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
EHPLEFMO_01677 2.3e-255 - - - S - - - DUF218 domain
EHPLEFMO_01678 7.53e-158 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
EHPLEFMO_01679 9.33e-256 napA - - P - - - Sodium/hydrogen exchanger family
EHPLEFMO_01680 0.0 cadA - - P - - - P-type ATPase
EHPLEFMO_01681 1.04e-110 ykuL - - S - - - (CBS) domain
EHPLEFMO_01682 3.22e-287 - - - S - - - Membrane
EHPLEFMO_01683 3.84e-65 - - - - - - - -
EHPLEFMO_01684 0.000111 - - - S - - - D-Ala-teichoic acid biosynthesis protein
EHPLEFMO_01685 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHPLEFMO_01686 1.36e-308 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
EHPLEFMO_01687 1.12e-49 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHPLEFMO_01688 2.21e-314 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EHPLEFMO_01690 1.01e-86 - - - S - - - Iron-sulphur cluster biosynthesis
EHPLEFMO_01691 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EHPLEFMO_01692 5.12e-81 - - - K - - - Bacterial regulatory proteins, tetR family
EHPLEFMO_01693 7.21e-37 - - - K - - - Bacterial regulatory proteins, tetR family
EHPLEFMO_01694 1.6e-127 - - - S - - - Cob(I)alamin adenosyltransferase
EHPLEFMO_01695 5.84e-123 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
EHPLEFMO_01697 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
EHPLEFMO_01698 2.09e-208 yvgN - - C - - - Aldo keto reductase
EHPLEFMO_01699 2.11e-221 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
EHPLEFMO_01700 5.2e-103 - - - - - - - -
EHPLEFMO_01701 2.64e-206 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
EHPLEFMO_01702 1.33e-70 - - - S - - - glycolate biosynthetic process
EHPLEFMO_01703 6.88e-24 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
EHPLEFMO_01704 3.57e-176 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EHPLEFMO_01705 9.2e-214 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EHPLEFMO_01706 2.49e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EHPLEFMO_01707 5.69e-234 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
EHPLEFMO_01708 4.3e-315 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EHPLEFMO_01709 1.21e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EHPLEFMO_01710 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
EHPLEFMO_01711 2.65e-228 - - - - - - - -
EHPLEFMO_01712 4.88e-88 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
EHPLEFMO_01713 9.16e-69 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
EHPLEFMO_01714 2.23e-105 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
EHPLEFMO_01715 6.16e-54 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
EHPLEFMO_01716 1.85e-143 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
EHPLEFMO_01717 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
EHPLEFMO_01718 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
EHPLEFMO_01719 4.32e-187 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
EHPLEFMO_01720 3.17e-182 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
EHPLEFMO_01721 5.37e-91 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
EHPLEFMO_01722 3.13e-73 - - - - - - - -
EHPLEFMO_01723 9.73e-32 - - - - - - - -
EHPLEFMO_01724 4.46e-74 - - - K - - - sequence-specific DNA binding
EHPLEFMO_01725 3.04e-234 - 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Rossmann-like domain
EHPLEFMO_01727 7.53e-60 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHPLEFMO_01728 5.42e-71 luxA_2 - - C - - - Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase
EHPLEFMO_01729 3.25e-193 - - - S - - - Protein of unknown function (DUF3298)
EHPLEFMO_01730 1.13e-127 - - - K ko:K03088 - ko00000,ko03021 Sigma-70 region 2
EHPLEFMO_01731 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EHPLEFMO_01732 3.23e-118 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
EHPLEFMO_01733 2.44e-136 - - - S - - - SNARE associated Golgi protein
EHPLEFMO_01734 3.71e-193 - - - I - - - alpha/beta hydrolase fold
EHPLEFMO_01735 2.83e-202 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
EHPLEFMO_01736 5.36e-122 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
EHPLEFMO_01737 1.64e-165 - - - F - - - glutamine amidotransferase
EHPLEFMO_01738 6.79e-42 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock protein
EHPLEFMO_01739 4.51e-65 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
EHPLEFMO_01740 4.48e-203 yicL - - EG - - - EamA-like transporter family
EHPLEFMO_01741 3.99e-179 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
EHPLEFMO_01742 1.1e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
EHPLEFMO_01743 1.59e-211 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
EHPLEFMO_01744 2.02e-306 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHPLEFMO_01745 2.42e-238 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHPLEFMO_01746 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
EHPLEFMO_01747 1.74e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
EHPLEFMO_01748 2.26e-83 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EHPLEFMO_01749 2.13e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EHPLEFMO_01751 4.62e-145 - - - - - - - -
EHPLEFMO_01753 1.12e-77 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EHPLEFMO_01754 3.32e-62 - - - K ko:K02529 - ko00000,ko03000 purine nucleotide biosynthetic process
EHPLEFMO_01755 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
EHPLEFMO_01756 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
EHPLEFMO_01757 7.15e-295 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EHPLEFMO_01758 4.69e-202 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EHPLEFMO_01759 0.0 - - - M - - - ErfK YbiS YcfS YnhG
EHPLEFMO_01761 5.33e-14 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
EHPLEFMO_01762 1.34e-153 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
EHPLEFMO_01763 0.0 bmr3_1 - - EGP ko:K18935 - ko00000,ko02000 Sugar (and other) transporter
EHPLEFMO_01764 2.82e-279 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHPLEFMO_01766 3.46e-258 - - - S - - - amidohydrolase
EHPLEFMO_01767 4.01e-08 XK27_07210 - - S - - - B3 4 domain
EHPLEFMO_01768 1.84e-64 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
EHPLEFMO_01769 6.1e-229 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
EHPLEFMO_01770 4.82e-06 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
EHPLEFMO_01771 2.29e-46 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
EHPLEFMO_01772 6.95e-217 - 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
EHPLEFMO_01773 4.56e-61 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
EHPLEFMO_01774 2.3e-184 - - - G - - - polysaccharide deacetylase
EHPLEFMO_01775 1.98e-13 - - - G - - - polysaccharide deacetylase
EHPLEFMO_01776 3.26e-161 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
EHPLEFMO_01777 2.58e-157 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
EHPLEFMO_01778 3.74e-104 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
EHPLEFMO_01779 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Aluminium induced protein
EHPLEFMO_01780 3.72e-205 - - - J - - - Methyltransferase
EHPLEFMO_01781 4.64e-139 pncA - - Q - - - Isochorismatase family
EHPLEFMO_01782 1.61e-148 - - - - - - - -
EHPLEFMO_01783 1.9e-56 - - - L - - - Membrane
EHPLEFMO_01784 2.32e-187 - - - F - - - NUDIX domain
EHPLEFMO_01785 1.45e-312 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
EHPLEFMO_01786 9.11e-34 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
EHPLEFMO_01787 8.9e-98 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHPLEFMO_01788 9.57e-106 tagD 2.7.7.15, 2.7.7.39 - IM ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Glycerol-3-phosphate cytidylyltransferase
EHPLEFMO_01789 2.6e-92 gtcA - - S - - - Teichoic acid glycosylation protein
EHPLEFMO_01790 4.44e-292 - - - L - - - COG3547 Transposase and inactivated derivatives
EHPLEFMO_01791 2.21e-297 - - - L - - - Transposase
EHPLEFMO_01792 3.92e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHPLEFMO_01793 1.92e-316 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
EHPLEFMO_01794 5.09e-61 - - GT2 S ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
EHPLEFMO_01795 2.09e-89 - - - L - - - Transposase DDE domain
EHPLEFMO_01796 4.15e-53 - - - L - - - Psort location Cytoplasmic, score

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)