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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HLDDABII_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLDDABII_00002	1.41e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLDDABII_00003	1.13e-104	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HLDDABII_00004	9.78e-14	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HLDDABII_00005	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HLDDABII_00006	1.7e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLDDABII_00007	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLDDABII_00008	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLDDABII_00009	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HLDDABII_00010	5.69e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLDDABII_00011	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLDDABII_00012	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HLDDABII_00013	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HLDDABII_00014	6.04e-307	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HLDDABII_00015	8.85e-268	yttB	-	-	EGP	-	-	-	Major Facilitator
HLDDABII_00016	3.85e-72	-	-	-	-	-	-	-	-
HLDDABII_00017	1.86e-210	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HLDDABII_00018	1.36e-215	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HLDDABII_00019	3.44e-12	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HLDDABII_00020	5.16e-164	-	-	-	O	-	-	-	Bacterial dnaA protein
HLDDABII_00021	1.6e-272	-	-	-	L	-	-	-	Integrase core domain
HLDDABII_00023	3.79e-96	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HLDDABII_00024	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HLDDABII_00026	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HLDDABII_00027	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDDABII_00028	9.74e-315	yycH	-	-	S	-	-	-	YycH protein
HLDDABII_00029	4.13e-192	yycI	-	-	S	-	-	-	YycH protein
HLDDABII_00030	2.52e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HLDDABII_00031	1.84e-282	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HLDDABII_00032	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HLDDABII_00033	1.81e-226	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HLDDABII_00034	2.9e-108	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLDDABII_00036	4.31e-120	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_00037	3.18e-103	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLDDABII_00038	1.1e-125	-	-	-	S	-	-	-	reductase
HLDDABII_00039	6.23e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HLDDABII_00040	2.41e-189	-	-	-	E	-	-	-	Glyoxalase-like domain
HLDDABII_00041	3.39e-186	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLDDABII_00042	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HLDDABII_00043	4.09e-200	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLDDABII_00044	4.85e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HLDDABII_00045	7.58e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HLDDABII_00046	5.54e-105	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLDDABII_00047	9.78e-132	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_00048	1.38e-65	-	-	-	-	-	-	-	-
HLDDABII_00049	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HLDDABII_00052	6.1e-104	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HLDDABII_00053	3.62e-244	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00054	2.44e-302	isp	-	-	L	-	-	-	Transposase
HLDDABII_00055	8.01e-97	-	-	-	O	-	-	-	OsmC-like protein
HLDDABII_00056	3.24e-226	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLDDABII_00057	9.71e-274	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLDDABII_00058	2.49e-43	-	-	-	-	-	-	-	-
HLDDABII_00059	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HLDDABII_00061	1.12e-135	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HLDDABII_00062	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLDDABII_00063	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HLDDABII_00064	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HLDDABII_00065	5.18e-222	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLDDABII_00066	7.36e-272	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HLDDABII_00067	2.77e-241	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HLDDABII_00068	6.62e-75	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HLDDABII_00069	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HLDDABII_00070	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HLDDABII_00071	1.76e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HLDDABII_00072	5.57e-99	-	-	-	-	-	-	-	-
HLDDABII_00073	1.76e-112	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HLDDABII_00074	3.15e-153	dltr	-	-	K	-	-	-	response regulator
HLDDABII_00075	1.13e-289	sptS	-	-	T	-	-	-	Histidine kinase
HLDDABII_00076	1.41e-265	-	-	-	P	-	-	-	Voltage gated chloride channel
HLDDABII_00077	2.89e-161	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HLDDABII_00078	6.13e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HLDDABII_00079	2.1e-214	-	-	-	C	-	-	-	Aldo keto reductase
HLDDABII_00080	1.86e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HLDDABII_00081	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HLDDABII_00082	7.6e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HLDDABII_00083	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HLDDABII_00084	6.39e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLDDABII_00085	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLDDABII_00086	1.98e-118	-	-	-	-	-	-	-	-
HLDDABII_00087	4.65e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLDDABII_00089	3.25e-18	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HLDDABII_00090	7.96e-97	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HLDDABII_00091	8.53e-95	-	-	-	-	-	-	-	-
HLDDABII_00092	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HLDDABII_00093	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HLDDABII_00094	0.0	-	-	-	M	-	-	-	domain protein
HLDDABII_00095	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HLDDABII_00096	3.62e-273	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HLDDABII_00097	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HLDDABII_00098	4.03e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HLDDABII_00099	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HLDDABII_00100	1.05e-229	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLDDABII_00101	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLDDABII_00103	8.9e-131	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HLDDABII_00104	1.73e-273	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HLDDABII_00105	3.98e-229	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLDDABII_00106	2.25e-77	-	-	-	L	-	-	-	Transposase
HLDDABII_00107	5.51e-173	-	-	-	L	-	-	-	Transposase
HLDDABII_00108	5.07e-137	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_00109	1.12e-82	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLDDABII_00110	3.89e-43	-	-	-	L	-	-	-	Transposase
HLDDABII_00111	3.33e-244	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00112	6.74e-35	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HLDDABII_00113	2.05e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HLDDABII_00114	1.66e-303	-	-	-	T	-	-	-	GHKL domain
HLDDABII_00115	1.32e-138	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HLDDABII_00116	1.2e-25	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
HLDDABII_00117	4.47e-12	-	-	-	P	-	-	-	FAD-binding domain
HLDDABII_00118	2e-73	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HLDDABII_00119	1.2e-106	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLDDABII_00120	4.09e-99	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HLDDABII_00121	2.32e-210	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HLDDABII_00122	1.94e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HLDDABII_00123	2.59e-135	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_00124	8.04e-149	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00125	2.67e-111	-	-	-	C	-	-	-	Flavodoxin
HLDDABII_00126	2.15e-203	lysR	-	-	K	-	-	-	Transcriptional regulator
HLDDABII_00127	7.41e-114	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HLDDABII_00128	8.09e-44	-	-	-	S	ko:K06889	-	ko00000	thiolester hydrolase activity
HLDDABII_00129	2.05e-195	-	-	-	S	-	-	-	Alpha beta hydrolase
HLDDABII_00130	2.49e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HLDDABII_00131	1.02e-120	-	-	-	K	-	-	-	Virulence activator alpha C-term
HLDDABII_00132	1.39e-83	-	-	-	GM	-	-	-	NAD(P)H-binding
HLDDABII_00133	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HLDDABII_00134	5.69e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HLDDABII_00135	4.47e-44	-	-	-	K	-	-	-	Transcriptional regulator
HLDDABII_00136	5.12e-133	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_00137	3.02e-52	-	-	-	K	-	-	-	Transcriptional regulator
HLDDABII_00138	7.26e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HLDDABII_00139	6.78e-136	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HLDDABII_00140	1.28e-105	-	-	-	S	-	-	-	membrane
HLDDABII_00141	3.43e-110	-	-	-	S	-	-	-	membrane
HLDDABII_00142	1.28e-144	-	-	-	GM	-	-	-	NAD(P)H-binding
HLDDABII_00143	1.74e-85	-	-	-	-	-	-	-	-
HLDDABII_00144	4.18e-168	-	-	-	F	-	-	-	glutamine amidotransferase
HLDDABII_00145	5.28e-181	-	-	-	T	-	-	-	EAL domain
HLDDABII_00146	1.17e-216	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HLDDABII_00147	2.6e-258	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
HLDDABII_00148	6.11e-158	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HLDDABII_00149	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HLDDABII_00150	1.43e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HLDDABII_00151	5.35e-121	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HLDDABII_00152	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HLDDABII_00153	7.17e-146	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
HLDDABII_00154	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HLDDABII_00155	7.6e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLDDABII_00156	7.97e-292	-	-	-	-	-	-	-	-
HLDDABII_00157	2.59e-34	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLDDABII_00158	3.83e-58	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLDDABII_00159	3.2e-138	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HLDDABII_00160	1.31e-67	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLDDABII_00161	7.48e-155	-	-	-	GM	-	-	-	NmrA-like family
HLDDABII_00162	5.36e-92	-	-	-	S	ko:K02348	-	ko00000	Gnat family
HLDDABII_00163	2.3e-52	-	-	-	S	-	-	-	Cytochrome B5
HLDDABII_00164	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
HLDDABII_00165	4.51e-54	-	-	-	S	-	-	-	Cytochrome B5
HLDDABII_00166	4.77e-270	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HLDDABII_00168	1.63e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLDDABII_00169	9.08e-317	-	-	-	E	ko:K03294	-	ko00000	amino acid
HLDDABII_00170	1.69e-183	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HLDDABII_00172	1.9e-118	-	-	-	L	-	-	-	Helix-turn-helix domain
HLDDABII_00173	1.84e-203	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HLDDABII_00174	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLDDABII_00175	1.89e-80	-	-	-	-	-	-	-	-
HLDDABII_00176	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HLDDABII_00177	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HLDDABII_00178	2.72e-113	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
HLDDABII_00179	2.39e-234	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HLDDABII_00180	2.44e-147	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDDABII_00181	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDDABII_00182	1.18e-50	-	-	-	-	-	-	-	-
HLDDABII_00183	1.17e-40	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HLDDABII_00184	1.17e-216	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HLDDABII_00185	1.7e-237	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00186	7.15e-315	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLDDABII_00187	3.11e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLDDABII_00188	2.14e-32	-	-	-	-	-	-	-	-
HLDDABII_00189	1.03e-146	-	-	-	-	-	-	-	-
HLDDABII_00190	4.99e-273	yttB	-	-	EGP	-	-	-	Major Facilitator
HLDDABII_00191	6.55e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HLDDABII_00192	2.46e-113	-	-	-	-	-	-	-	-
HLDDABII_00193	4.3e-142	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HLDDABII_00194	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HLDDABII_00195	1.27e-51	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HLDDABII_00196	4.16e-267	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HLDDABII_00197	2.54e-133	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_00198	5.09e-162	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HLDDABII_00200	1.93e-131	-	-	-	-	-	-	-	-
HLDDABII_00201	1.01e-67	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_00202	4.25e-103	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLDDABII_00203	1.02e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HLDDABII_00204	2.56e-188	-	-	-	S	-	-	-	Alpha beta hydrolase
HLDDABII_00205	2.84e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
HLDDABII_00206	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLDDABII_00207	1.77e-56	-	-	-	-	-	-	-	-
HLDDABII_00208	3.18e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HLDDABII_00209	3.39e-33	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HLDDABII_00210	9.8e-305	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HLDDABII_00211	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HLDDABII_00212	4.79e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HLDDABII_00213	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLDDABII_00214	0.0	-	-	-	L	-	-	-	Transposase
HLDDABII_00215	2.35e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HLDDABII_00216	8.16e-212	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HLDDABII_00217	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HLDDABII_00218	4.38e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HLDDABII_00219	7.25e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HLDDABII_00220	1.05e-44	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HLDDABII_00221	1.14e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HLDDABII_00222	1.85e-117	-	-	-	P	-	-	-	Cadmium resistance transporter
HLDDABII_00223	5.63e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDDABII_00224	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HLDDABII_00225	3.16e-233	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HLDDABII_00226	1.9e-165	-	-	-	M	-	-	-	PFAM NLP P60 protein
HLDDABII_00228	2.62e-121	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HLDDABII_00229	5.56e-25	-	-	-	-	-	-	-	-
HLDDABII_00230	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HLDDABII_00231	8.04e-184	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HLDDABII_00232	7.28e-138	-	-	-	NU	-	-	-	mannosyl-glycoprotein
HLDDABII_00233	1.8e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HLDDABII_00234	6.07e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HLDDABII_00235	5.28e-262	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HLDDABII_00236	5.87e-65	-	-	-	-	-	-	-	-
HLDDABII_00237	1.62e-34	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HLDDABII_00238	5.16e-43	-	2.1.1.72	-	D	ko:K03427	-	ko00000,ko01000,ko02048	peptidase
HLDDABII_00239	6.47e-72	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HLDDABII_00241	2.84e-73	-	-	-	-	-	-	-	-
HLDDABII_00242	7.94e-150	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HLDDABII_00244	3.47e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HLDDABII_00245	1.92e-153	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HLDDABII_00246	1.46e-261	-	-	-	S	-	-	-	associated with various cellular activities
HLDDABII_00247	1.32e-307	-	-	-	S	-	-	-	Putative metallopeptidase domain
HLDDABII_00248	4.95e-63	-	-	-	-	-	-	-	-
HLDDABII_00249	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HLDDABII_00250	2.13e-142	-	-	-	K	-	-	-	Helix-turn-helix domain
HLDDABII_00251	2.18e-115	ymdB	-	-	S	-	-	-	Macro domain protein
HLDDABII_00252	7.33e-253	-	-	-	EGP	-	-	-	Major Facilitator
HLDDABII_00253	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLDDABII_00254	1.39e-69	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLDDABII_00255	3.74e-213	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HLDDABII_00256	4.9e-202	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HLDDABII_00257	5.14e-46	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HLDDABII_00258	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HLDDABII_00259	4.29e-175	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDDABII_00260	5.89e-231	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
HLDDABII_00261	9.04e-171	XK27_10500	-	-	K	-	-	-	response regulator
HLDDABII_00262	7.23e-202	yvgN	-	-	S	-	-	-	Aldo keto reductase
HLDDABII_00263	9.74e-176	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HLDDABII_00264	4.74e-107	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLDDABII_00265	2.24e-261	-	-	-	-	-	-	-	-
HLDDABII_00266	1.24e-68	-	-	-	-	-	-	-	-
HLDDABII_00267	1.21e-48	-	-	-	-	-	-	-	-
HLDDABII_00268	5.55e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HLDDABII_00269	5.69e-189	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HLDDABII_00270	1.34e-234	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HLDDABII_00271	8.5e-287	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLDDABII_00272	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HLDDABII_00273	1.97e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HLDDABII_00274	2.56e-133	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HLDDABII_00275	8.33e-294	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLDDABII_00276	2.7e-104	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HLDDABII_00277	2.71e-103	usp5	-	-	T	-	-	-	universal stress protein
HLDDABII_00278	2.07e-61	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HLDDABII_00279	5.08e-77	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HLDDABII_00280	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HLDDABII_00281	1.83e-54	-	-	-	-	-	-	-	-
HLDDABII_00282	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLDDABII_00283	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLDDABII_00284	3.03e-246	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HLDDABII_00285	3.68e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
HLDDABII_00286	1.98e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HLDDABII_00287	1.67e-307	yhdP	-	-	S	-	-	-	Transporter associated domain
HLDDABII_00288	1.39e-198	-	-	-	V	-	-	-	(ABC) transporter
HLDDABII_00289	3.16e-114	-	-	-	GM	-	-	-	epimerase
HLDDABII_00290	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HLDDABII_00291	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
HLDDABII_00292	7.74e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
HLDDABII_00293	1.32e-236	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
HLDDABII_00294	1.92e-202	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HLDDABII_00295	6.14e-207	-	-	-	-	-	-	-	-
HLDDABII_00296	1.99e-90	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00297	3.2e-36	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00298	2.86e-40	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00299	4.17e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HLDDABII_00300	5.75e-242	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLDDABII_00301	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HLDDABII_00302	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HLDDABII_00303	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLDDABII_00304	1.65e-113	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLDDABII_00305	3.02e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HLDDABII_00306	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HLDDABII_00307	4.29e-310	-	-	-	E	-	-	-	amino acid
HLDDABII_00308	4.49e-180	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HLDDABII_00309	2.29e-309	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HLDDABII_00310	2.17e-213	-	-	-	GK	-	-	-	ROK family
HLDDABII_00311	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HLDDABII_00312	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
HLDDABII_00313	1.42e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HLDDABII_00314	1.78e-83	-	-	-	-	-	-	-	-
HLDDABII_00315	3.18e-11	-	-	-	-	-	-	-	-
HLDDABII_00316	3.93e-270	-	-	-	EGP	-	-	-	Major Facilitator
HLDDABII_00317	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HLDDABII_00318	9.77e-231	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HLDDABII_00319	3.46e-207	-	-	-	-	-	-	-	-
HLDDABII_00320	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
HLDDABII_00321	2.53e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HLDDABII_00322	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HLDDABII_00323	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HLDDABII_00324	6.5e-71	-	-	-	-	-	-	-	-
HLDDABII_00325	2.91e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HLDDABII_00326	4.68e-314	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLDDABII_00327	8.59e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HLDDABII_00328	1.47e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLDDABII_00329	7.72e-178	-	-	-	IQ	-	-	-	KR domain
HLDDABII_00330	5.46e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HLDDABII_00331	3.42e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HLDDABII_00332	5e-194	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HLDDABII_00333	1.33e-162	-	-	-	L	-	-	-	Helix-turn-helix domain
HLDDABII_00334	1.86e-62	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HLDDABII_00335	9.45e-152	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HLDDABII_00336	6.87e-95	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLDDABII_00337	1.96e-95	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLDDABII_00338	0.0	yagE	-	-	E	-	-	-	amino acid
HLDDABII_00339	4.16e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HLDDABII_00340	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HLDDABII_00341	8.65e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HLDDABII_00342	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HLDDABII_00343	1.46e-261	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HLDDABII_00344	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLDDABII_00345	5.39e-184	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLDDABII_00346	4.91e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLDDABII_00347	1.33e-178	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HLDDABII_00348	8.03e-52	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HLDDABII_00349	1.97e-293	-	-	-	-	-	-	-	-
HLDDABII_00350	1.77e-298	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HLDDABII_00351	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HLDDABII_00352	3.59e-97	-	-	-	F	-	-	-	Nudix hydrolase
HLDDABII_00353	1.12e-131	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HLDDABII_00354	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HLDDABII_00355	6.02e-34	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HLDDABII_00356	4.65e-193	-	-	-	-	-	-	-	-
HLDDABII_00357	8.65e-53	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HLDDABII_00358	7.15e-122	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HLDDABII_00359	2.16e-316	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HLDDABII_00360	3.17e-233	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLDDABII_00361	6.08e-13	-	-	-	S	-	-	-	CsbD-like
HLDDABII_00362	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
HLDDABII_00363	1.27e-291	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLDDABII_00364	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HLDDABII_00365	2.31e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HLDDABII_00366	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLDDABII_00367	1.35e-43	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HLDDABII_00368	3.23e-196	-	-	-	EG	-	-	-	EamA-like transporter family
HLDDABII_00369	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLDDABII_00370	3.39e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HLDDABII_00371	4.94e-288	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HLDDABII_00373	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HLDDABII_00374	2.1e-288	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HLDDABII_00375	1.35e-202	-	-	-	J	-	-	-	Methyltransferase
HLDDABII_00376	3.63e-167	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00377	1.53e-147	-	-	-	S	-	-	-	Membrane
HLDDABII_00378	1.98e-83	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
HLDDABII_00379	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLDDABII_00380	4.16e-200	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HLDDABII_00382	1.01e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HLDDABII_00383	9.08e-106	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HLDDABII_00384	1.54e-234	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HLDDABII_00385	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLDDABII_00386	3.89e-243	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00387	1.45e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
HLDDABII_00388	8.12e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HLDDABII_00389	1.31e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HLDDABII_00390	5.82e-194	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HLDDABII_00391	1.82e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLDDABII_00392	1.43e-160	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HLDDABII_00393	9.4e-197	-	-	-	-	-	-	-	-
HLDDABII_00394	6.13e-149	-	-	-	M	-	-	-	Glycosyl transferase
HLDDABII_00395	5.02e-141	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HLDDABII_00396	2.38e-137	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HLDDABII_00397	5.77e-128	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HLDDABII_00398	1.29e-279	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HLDDABII_00399	5.1e-120	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HLDDABII_00400	3.27e-36	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HLDDABII_00401	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HLDDABII_00402	3.91e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HLDDABII_00403	2.8e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HLDDABII_00404	2.66e-114	-	-	-	Q	-	-	-	Methyltransferase
HLDDABII_00405	1.27e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HLDDABII_00406	7.72e-228	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HLDDABII_00407	3.23e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HLDDABII_00408	2.8e-119	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HLDDABII_00409	8.15e-298	-	-	-	G	ko:K03832	-	ko00000,ko02000	Belongs to the glycosyl hydrolase family 6
HLDDABII_00410	2.89e-230	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HLDDABII_00411	5.26e-174	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLDDABII_00412	4.83e-215	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HLDDABII_00413	7.42e-228	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HLDDABII_00414	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HLDDABII_00415	0.0	arcT	-	-	E	-	-	-	Dipeptidase
HLDDABII_00416	3.66e-274	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HLDDABII_00417	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HLDDABII_00418	3.66e-183	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HLDDABII_00419	3.22e-147	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00420	1.08e-81	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00421	9.29e-290	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HLDDABII_00422	4.41e-96	-	-	-	-	-	-	-	-
HLDDABII_00423	3.02e-254	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HLDDABII_00424	1.36e-35	-	-	-	-	-	-	-	-
HLDDABII_00425	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HLDDABII_00426	1.05e-205	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HLDDABII_00427	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
HLDDABII_00428	1.35e-263	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
HLDDABII_00429	2.87e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLDDABII_00430	5.46e-207	mleR	-	-	K	-	-	-	LysR family
HLDDABII_00431	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HLDDABII_00432	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HLDDABII_00433	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HLDDABII_00434	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HLDDABII_00435	7.21e-205	-	-	-	K	-	-	-	LysR family
HLDDABII_00436	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HLDDABII_00437	2.22e-151	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HLDDABII_00438	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HLDDABII_00439	1.93e-241	-	-	-	I	-	-	-	Alpha beta
HLDDABII_00440	5.59e-134	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HLDDABII_00441	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLDDABII_00443	2.24e-205	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLDDABII_00444	1.91e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HLDDABII_00445	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HLDDABII_00446	1.26e-96	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HLDDABII_00447	9.15e-72	-	-	-	-	-	-	-	-
HLDDABII_00448	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLDDABII_00449	3.54e-276	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLDDABII_00450	2.11e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLDDABII_00451	1.06e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLDDABII_00452	1.63e-196	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLDDABII_00453	8.01e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLDDABII_00454	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HLDDABII_00455	2.72e-141	-	-	-	S	-	-	-	VIT family
HLDDABII_00456	7.33e-152	-	-	-	S	-	-	-	membrane
HLDDABII_00457	2.85e-212	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HLDDABII_00458	9.44e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HLDDABII_00459	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HLDDABII_00460	2.09e-166	-	-	-	S	-	-	-	Putative threonine/serine exporter
HLDDABII_00461	2.05e-104	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HLDDABII_00462	8.01e-153	-	-	-	I	-	-	-	phosphatase
HLDDABII_00464	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HLDDABII_00465	6.4e-149	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HLDDABII_00471	8.47e-154	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HLDDABII_00472	4.62e-21	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HLDDABII_00473	8.94e-250	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HLDDABII_00474	3.99e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HLDDABII_00475	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HLDDABII_00476	4.92e-142	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLDDABII_00477	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLDDABII_00478	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLDDABII_00479	1.15e-263	-	-	-	-	-	-	-	-
HLDDABII_00480	1.97e-153	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HLDDABII_00481	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLDDABII_00482	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLDDABII_00483	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLDDABII_00484	2.75e-82	isp	-	-	L	-	-	-	Transposase
HLDDABII_00485	5.74e-171	isp	-	-	L	-	-	-	Transposase
HLDDABII_00486	1.77e-103	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLDDABII_00487	8.96e-92	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_00488	5.22e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HLDDABII_00489	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLDDABII_00490	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HLDDABII_00491	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLDDABII_00492	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLDDABII_00493	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLDDABII_00494	8.8e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLDDABII_00495	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLDDABII_00496	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLDDABII_00497	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HLDDABII_00498	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLDDABII_00499	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLDDABII_00500	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLDDABII_00501	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLDDABII_00502	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLDDABII_00503	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLDDABII_00504	1.06e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLDDABII_00505	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLDDABII_00506	1.2e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLDDABII_00507	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HLDDABII_00508	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HLDDABII_00509	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLDDABII_00510	7.5e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLDDABII_00511	9.82e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLDDABII_00512	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HLDDABII_00513	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLDDABII_00514	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLDDABII_00515	8.91e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLDDABII_00516	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HLDDABII_00517	1.23e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLDDABII_00518	9.73e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLDDABII_00519	7.93e-179	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLDDABII_00520	6.12e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLDDABII_00521	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLDDABII_00522	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HLDDABII_00523	4.46e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HLDDABII_00524	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HLDDABII_00525	3.91e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLDDABII_00526	8.91e-270	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HLDDABII_00527	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HLDDABII_00528	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLDDABII_00529	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
HLDDABII_00530	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLDDABII_00531	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLDDABII_00532	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLDDABII_00533	5.06e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HLDDABII_00534	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLDDABII_00535	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HLDDABII_00536	9.38e-233	-	-	-	M	-	-	-	domain protein
HLDDABII_00537	8.23e-23	-	2.1.1.303	-	K	ko:K04096,ko:K20421	ko01059,ko01130,map01059,map01130	ko00000,ko00001,ko00002,ko01000	DNA-binding transcription factor activity
HLDDABII_00538	0.0	-	-	-	L	-	-	-	Recombinase
HLDDABII_00539	0.0	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HLDDABII_00540	4.44e-37	-	-	-	-	-	-	-	-
HLDDABII_00541	2.16e-89	-	-	-	S	-	-	-	Bacteriophage holin family
HLDDABII_00542	1.29e-88	-	-	-	S	-	-	-	Phage head-tail joining protein
HLDDABII_00543	1.78e-56	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HLDDABII_00544	1.85e-265	-	-	-	S	-	-	-	Phage capsid family
HLDDABII_00545	1.96e-148	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HLDDABII_00546	2.03e-311	-	-	-	S	-	-	-	Phage portal protein
HLDDABII_00547	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HLDDABII_00548	4e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF5049)
HLDDABII_00549	2.03e-128	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLDDABII_00550	1.9e-298	-	-	-	KL	-	-	-	DNA methylase
HLDDABII_00551	2.31e-128	-	-	-	-	-	-	-	-
HLDDABII_00552	4.68e-109	-	-	-	-	-	-	-	-
HLDDABII_00553	8.11e-315	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HLDDABII_00554	6.15e-62	-	-	-	S	-	-	-	VRR_NUC
HLDDABII_00555	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HLDDABII_00556	1.02e-89	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLDDABII_00557	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
HLDDABII_00558	2.14e-125	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
HLDDABII_00559	9.16e-264	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
HLDDABII_00560	6.48e-58	-	-	-	-	-	-	-	-
HLDDABII_00561	1.66e-34	-	-	-	-	-	-	-	-
HLDDABII_00563	1.52e-188	-	-	-	-	-	-	-	-
HLDDABII_00564	2.7e-34	-	-	-	-	-	-	-	-
HLDDABII_00565	1.59e-291	-	-	-	-	-	-	-	-
HLDDABII_00566	1.77e-51	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HLDDABII_00567	2.17e-141	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
HLDDABII_00568	7.04e-190	isp	-	-	L	-	-	-	Transposase
HLDDABII_00569	8.29e-70	isp	-	-	L	-	-	-	Transposase
HLDDABII_00570	1.32e-154	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
HLDDABII_00571	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HLDDABII_00572	2.28e-276	-	-	-	K	-	-	-	DNA binding
HLDDABII_00573	0.0	-	-	-	L	-	-	-	helicase activity
HLDDABII_00576	1.51e-300	-	-	-	L	-	-	-	Integrase core domain
HLDDABII_00577	1.37e-103	-	-	-	L	-	-	-	helicase activity
HLDDABII_00579	1.03e-72	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLDDABII_00580	6.37e-14	-	-	-	-	-	-	-	-
HLDDABII_00581	2.44e-116	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00582	9.47e-72	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00583	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HLDDABII_00584	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
HLDDABII_00585	1.01e-120	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HLDDABII_00586	9.73e-146	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HLDDABII_00587	2.93e-48	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00588	1.6e-137	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00589	1.4e-34	-	-	-	K	-	-	-	TRANSCRIPTIONal
HLDDABII_00590	1.65e-83	yju3	-	-	I	-	-	-	Serine aminopeptidase, S33
HLDDABII_00591	1.56e-102	pncA	-	-	Q	-	-	-	Isochorismatase family
HLDDABII_00592	6.08e-289	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLDDABII_00593	1.76e-143	-	-	-	F	-	-	-	NUDIX domain
HLDDABII_00594	2.97e-166	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00595	8.13e-123	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HLDDABII_00596	3.81e-62	-	-	-	-	-	-	-	-
HLDDABII_00598	3.44e-47	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HLDDABII_00599	7.82e-237	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HLDDABII_00600	4.32e-314	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HLDDABII_00601	1.65e-114	XK27_07210	-	-	S	-	-	-	B3 4 domain
HLDDABII_00602	8.65e-119	-	-	-	-	-	-	-	-
HLDDABII_00603	1.46e-156	pnb	-	-	C	-	-	-	nitroreductase
HLDDABII_00604	3.43e-96	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HLDDABII_00605	1.93e-216	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HLDDABII_00606	7.88e-215	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HLDDABII_00607	7.28e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HLDDABII_00608	1.05e-102	-	-	-	K	-	-	-	LytTr DNA-binding domain
HLDDABII_00609	1.2e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HLDDABII_00610	7.31e-27	-	-	-	-	-	-	-	-
HLDDABII_00611	6.48e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HLDDABII_00612	2.25e-105	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HLDDABII_00613	2.87e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
HLDDABII_00614	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HLDDABII_00615	1.86e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HLDDABII_00616	1.25e-136	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HLDDABII_00617	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HLDDABII_00618	5.34e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HLDDABII_00619	7.11e-293	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HLDDABII_00621	2.09e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLDDABII_00622	2.02e-72	-	-	-	-	-	-	-	-
HLDDABII_00623	4.94e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HLDDABII_00624	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HLDDABII_00625	1e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HLDDABII_00626	3.98e-280	arcT	-	-	E	-	-	-	Aminotransferase
HLDDABII_00627	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HLDDABII_00628	0.0	potE	-	-	E	-	-	-	Amino Acid
HLDDABII_00629	7.47e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HLDDABII_00630	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HLDDABII_00631	2.53e-42	-	-	-	-	-	-	-	-
HLDDABII_00632	8.57e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HLDDABII_00633	2.23e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HLDDABII_00634	3.96e-225	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HLDDABII_00635	6.93e-154	-	-	-	M	-	-	-	Bacterial sugar transferase
HLDDABII_00636	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
HLDDABII_00637	6.21e-173	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
HLDDABII_00638	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
HLDDABII_00639	4.46e-46	-	-	-	-	-	-	-	-
HLDDABII_00640	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HLDDABII_00641	1.75e-278	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HLDDABII_00642	1.14e-263	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HLDDABII_00643	8.59e-95	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HLDDABII_00644	2.45e-107	-	-	-	-	-	-	-	-
HLDDABII_00645	6.82e-38	-	-	-	M	-	-	-	biosynthesis protein
HLDDABII_00646	3.13e-95	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HLDDABII_00647	7.27e-83	-	-	-	S	-	-	-	Glycosyltransferase like family
HLDDABII_00648	1e-97	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
HLDDABII_00649	3.78e-88	-	-	-	S	-	-	-	Acyltransferase family
HLDDABII_00651	2.26e-90	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLDDABII_00652	1.39e-209	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HLDDABII_00654	6.59e-65	-	-	-	S	-	-	-	integral membrane protein
HLDDABII_00655	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLDDABII_00656	1.65e-207	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLDDABII_00657	5.58e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HLDDABII_00658	1.34e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLDDABII_00659	2.33e-202	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HLDDABII_00660	0.0	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
HLDDABII_00661	9.19e-233	yueF	-	-	S	-	-	-	AI-2E family transporter
HLDDABII_00662	2.39e-301	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HLDDABII_00663	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HLDDABII_00664	1.41e-43	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00665	5.95e-187	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00666	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HLDDABII_00667	9.47e-202	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDDABII_00668	7.87e-146	-	-	-	-	-	-	-	-
HLDDABII_00669	1.35e-182	-	-	-	G	-	-	-	MucBP domain
HLDDABII_00670	7.43e-129	-	-	-	S	-	-	-	Pfam:DUF3816
HLDDABII_00671	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HLDDABII_00672	1.38e-37	-	-	-	-	-	-	-	-
HLDDABII_00673	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HLDDABII_00674	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLDDABII_00675	2.99e-289	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HLDDABII_00676	1.09e-250	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HLDDABII_00677	3.8e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLDDABII_00678	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HLDDABII_00679	6.36e-75	-	-	-	-	-	-	-	-
HLDDABII_00689	1.74e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLDDABII_00690	3.14e-310	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HLDDABII_00691	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HLDDABII_00692	3.94e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLDDABII_00693	3.48e-192	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
HLDDABII_00694	2.73e-148	-	-	-	M	-	-	-	LysM domain protein
HLDDABII_00695	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
HLDDABII_00696	4.57e-137	-	-	-	M	-	-	-	LysM domain protein
HLDDABII_00697	4.66e-73	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_00698	4.1e-103	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLDDABII_00699	7.77e-198	yeaE	-	-	S	-	-	-	Aldo keto
HLDDABII_00700	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HLDDABII_00701	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HLDDABII_00702	3.1e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLDDABII_00703	0.0	-	-	-	L	-	-	-	Transposase
HLDDABII_00704	5.03e-111	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HLDDABII_00705	7.03e-33	-	-	-	-	-	-	-	-
HLDDABII_00706	8.28e-135	-	-	-	V	-	-	-	VanZ like family
HLDDABII_00707	1.41e-302	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HLDDABII_00708	1.25e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HLDDABII_00709	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HLDDABII_00710	4.29e-119	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HLDDABII_00711	2.71e-280	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLDDABII_00712	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HLDDABII_00713	1.45e-55	-	-	-	-	-	-	-	-
HLDDABII_00714	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HLDDABII_00715	4.62e-192	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLDDABII_00716	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HLDDABII_00717	4.4e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HLDDABII_00718	1.11e-224	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLDDABII_00719	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HLDDABII_00720	3.08e-146	-	-	-	-	-	-	-	-
HLDDABII_00721	8.42e-237	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HLDDABII_00722	1.63e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLDDABII_00723	1.52e-43	-	-	-	-	-	-	-	-
HLDDABII_00724	1.05e-153	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLDDABII_00725	2.17e-57	-	-	-	-	-	-	-	-
HLDDABII_00727	6.82e-72	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HLDDABII_00728	4.71e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HLDDABII_00729	3.36e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HLDDABII_00730	8.17e-285	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HLDDABII_00731	2.97e-136	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HLDDABII_00732	1.62e-277	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HLDDABII_00733	9.3e-61	-	-	-	-	-	-	-	-
HLDDABII_00734	1.49e-54	-	-	-	-	-	-	-	-
HLDDABII_00736	3.88e-213	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HLDDABII_00737	2.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HLDDABII_00738	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HLDDABII_00739	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HLDDABII_00740	3.75e-77	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HLDDABII_00741	2.62e-282	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HLDDABII_00742	0.0	yhaN	-	-	L	-	-	-	AAA domain
HLDDABII_00743	3.96e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLDDABII_00745	4.99e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HLDDABII_00746	2.7e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDDABII_00747	6.64e-279	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HLDDABII_00748	1.85e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLDDABII_00749	3.31e-37	-	-	-	S	-	-	-	YSIRK type signal peptide
HLDDABII_00750	1.05e-39	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HLDDABII_00751	5.66e-311	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HLDDABII_00752	6.79e-183	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HLDDABII_00753	5.88e-126	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HLDDABII_00754	9.43e-233	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HLDDABII_00755	1.31e-152	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HLDDABII_00756	8.37e-25	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HLDDABII_00757	3.23e-75	-	-	-	S	-	-	-	Small secreted protein
HLDDABII_00758	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HLDDABII_00759	1.63e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLDDABII_00760	7.39e-64	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HLDDABII_00761	8.55e-46	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HLDDABII_00762	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HLDDABII_00763	6.48e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HLDDABII_00764	5.63e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HLDDABII_00765	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLDDABII_00766	2.74e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLDDABII_00767	4.19e-128	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLDDABII_00768	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLDDABII_00769	3.31e-275	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HLDDABII_00770	9.62e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HLDDABII_00771	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLDDABII_00772	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HLDDABII_00773	2.23e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLDDABII_00774	3.17e-124	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HLDDABII_00775	5.44e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HLDDABII_00776	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HLDDABII_00777	1.15e-156	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLDDABII_00778	3.6e-146	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HLDDABII_00779	1.9e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLDDABII_00780	1.1e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
HLDDABII_00781	7.96e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HLDDABII_00782	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HLDDABII_00783	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HLDDABII_00784	2.29e-154	csrR	-	-	K	-	-	-	response regulator
HLDDABII_00785	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDDABII_00786	0.0	potE	-	-	E	-	-	-	Amino Acid
HLDDABII_00787	7.99e-293	-	-	-	V	-	-	-	MatE
HLDDABII_00788	9.16e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HLDDABII_00789	3.89e-215	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLDDABII_00790	1.79e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HLDDABII_00791	2.22e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLDDABII_00792	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLDDABII_00793	2.36e-77	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLDDABII_00794	2.12e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLDDABII_00795	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLDDABII_00796	6.92e-148	-	-	-	M	-	-	-	PFAM NLP P60 protein
HLDDABII_00797	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HLDDABII_00798	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLDDABII_00799	9.16e-99	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HLDDABII_00800	1.33e-91	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HLDDABII_00801	0.0	-	-	-	S	-	-	-	membrane
HLDDABII_00802	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HLDDABII_00803	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HLDDABII_00804	9.34e-130	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLDDABII_00805	1.43e-16	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HLDDABII_00806	7.32e-35	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HLDDABII_00807	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HLDDABII_00808	1.02e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HLDDABII_00809	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HLDDABII_00810	2.39e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HLDDABII_00811	1.01e-226	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLDDABII_00812	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HLDDABII_00813	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLDDABII_00814	8.1e-281	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLDDABII_00815	1.28e-18	-	-	-	-	-	-	-	-
HLDDABII_00816	1.14e-195	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HLDDABII_00817	1.64e-130	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLDDABII_00818	1.54e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HLDDABII_00819	4.87e-203	-	-	-	-	-	-	-	-
HLDDABII_00820	1.47e-223	-	-	-	-	-	-	-	-
HLDDABII_00821	4.21e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
HLDDABII_00825	1.34e-144	-	-	-	K	-	-	-	Transcriptional regulator
HLDDABII_00826	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HLDDABII_00827	1.77e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HLDDABII_00828	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HLDDABII_00829	3.84e-170	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HLDDABII_00830	1.5e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HLDDABII_00831	1e-146	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
HLDDABII_00832	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HLDDABII_00833	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLDDABII_00834	1.61e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLDDABII_00835	1.09e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLDDABII_00836	4.02e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLDDABII_00837	6.95e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLDDABII_00838	1.69e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HLDDABII_00839	3.2e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HLDDABII_00840	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HLDDABII_00841	9e-72	-	-	-	-	-	-	-	-
HLDDABII_00842	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HLDDABII_00843	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLDDABII_00844	4.44e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLDDABII_00845	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLDDABII_00846	8.26e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLDDABII_00847	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLDDABII_00848	4.26e-168	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HLDDABII_00849	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HLDDABII_00850	3.08e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLDDABII_00851	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HLDDABII_00852	5.49e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HLDDABII_00853	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HLDDABII_00854	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HLDDABII_00855	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HLDDABII_00856	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLDDABII_00857	4.72e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLDDABII_00858	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLDDABII_00859	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLDDABII_00860	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HLDDABII_00861	4.94e-285	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLDDABII_00862	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLDDABII_00863	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLDDABII_00864	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HLDDABII_00865	1.78e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HLDDABII_00866	7.57e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLDDABII_00867	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HLDDABII_00868	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
HLDDABII_00869	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLDDABII_00870	3.67e-46	-	-	-	-	-	-	-	-
HLDDABII_00871	9e-72	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
HLDDABII_00872	8.83e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HLDDABII_00873	1.55e-109	-	-	-	-	-	-	-	-
HLDDABII_00874	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HLDDABII_00875	5.66e-143	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLDDABII_00876	1.06e-50	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLDDABII_00877	1.4e-58	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HLDDABII_00878	1.35e-238	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HLDDABII_00879	2.82e-133	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HLDDABII_00880	5.71e-286	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HLDDABII_00881	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HLDDABII_00882	1.23e-193	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLDDABII_00883	9.88e-109	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLDDABII_00884	4.26e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLDDABII_00885	9.02e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HLDDABII_00886	3.03e-166	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HLDDABII_00887	2.99e-290	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HLDDABII_00888	9.61e-213	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HLDDABII_00889	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLDDABII_00890	9.99e-68	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HLDDABII_00891	4.84e-233	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HLDDABII_00894	1.45e-153	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HLDDABII_00895	4.78e-193	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HLDDABII_00896	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
HLDDABII_00897	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HLDDABII_00898	1.07e-148	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HLDDABII_00899	2.77e-48	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLDDABII_00902	2.87e-133	-	-	-	O	-	-	-	Bacterial dnaA protein
HLDDABII_00903	1.95e-273	-	-	-	L	-	-	-	Integrase core domain
HLDDABII_00904	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLDDABII_00905	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HLDDABII_00906	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HLDDABII_00907	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLDDABII_00908	2.64e-114	-	-	-	-	-	-	-	-
HLDDABII_00909	8e-49	-	-	-	-	-	-	-	-
HLDDABII_00910	1.64e-13	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLDDABII_00911	1.11e-218	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HLDDABII_00912	2.76e-191	epsB	-	-	M	-	-	-	biosynthesis protein
HLDDABII_00913	8.1e-159	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HLDDABII_00914	1.44e-67	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HLDDABII_00915	4.16e-38	-	-	-	S	ko:K07011	-	ko00000	glycosyl transferase family 2
HLDDABII_00916	1.5e-67	-	-	-	M	-	-	-	Glycosyl transferases group 1
HLDDABII_00917	7.48e-12	-	-	-	S	-	-	-	Glycosyl transferase family 2
HLDDABII_00918	6.29e-44	-	-	-	M	-	-	-	Glycosyl transferase family 2
HLDDABII_00920	1.49e-107	-	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLDDABII_00921	3.88e-206	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLDDABII_00922	7.93e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HLDDABII_00923	1.34e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLDDABII_00924	3.45e-200	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HLDDABII_00925	2.45e-133	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_00926	9.97e-104	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HLDDABII_00927	8.04e-128	-	-	-	K	-	-	-	UTRA
HLDDABII_00928	3.51e-210	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HLDDABII_00929	8.42e-46	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HLDDABII_00930	1.54e-38	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HLDDABII_00931	6.07e-150	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
HLDDABII_00933	1.07e-240	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00934	1.67e-87	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HLDDABII_00935	5.16e-292	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HLDDABII_00936	2.59e-31	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
HLDDABII_00937	6.49e-49	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
HLDDABII_00939	0.0	snf	-	-	KL	-	-	-	domain protein
HLDDABII_00940	2.71e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HLDDABII_00941	2.63e-264	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HLDDABII_00942	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HLDDABII_00943	4.75e-137	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_00944	5.54e-105	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLDDABII_00945	8.88e-243	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_00946	3e-93	-	-	-	-	-	-	-	-
HLDDABII_00949	5.65e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
HLDDABII_00950	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HLDDABII_00951	1.88e-290	-	-	-	P	-	-	-	Chloride transporter, ClC family
HLDDABII_00952	5.25e-149	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HLDDABII_00953	8.93e-150	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HLDDABII_00954	3.07e-25	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HLDDABII_00955	2.18e-177	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HLDDABII_00956	2.05e-66	-	-	-	-	-	-	-	-
HLDDABII_00957	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
HLDDABII_00958	1.12e-82	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLDDABII_00959	1.23e-136	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_00960	6.34e-95	-	-	-	-	-	-	-	-
HLDDABII_00961	7.92e-221	-	-	-	-	-	-	-	-
HLDDABII_00962	7.67e-229	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HLDDABII_00963	1.14e-178	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HLDDABII_00964	4.18e-165	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLDDABII_00965	1.79e-101	-	-	-	S	-	-	-	Flavodoxin
HLDDABII_00966	3.25e-84	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HLDDABII_00967	4.04e-48	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
HLDDABII_00968	5.25e-279	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
HLDDABII_00969	4.74e-213	-	-	-	H	-	-	-	geranyltranstransferase activity
HLDDABII_00970	9.46e-235	-	-	-	-	-	-	-	-
HLDDABII_00971	3.11e-26	-	-	-	-	-	-	-	-
HLDDABII_00972	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HLDDABII_00973	9.18e-243	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
HLDDABII_00974	1.56e-60	-	-	-	-	-	-	-	-
HLDDABII_00975	2.37e-135	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HLDDABII_00976	9.66e-110	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HLDDABII_00977	2.19e-291	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
HLDDABII_00978	1.65e-107	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HLDDABII_00979	5.49e-238	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HLDDABII_00980	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLDDABII_00981	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HLDDABII_00982	4.54e-125	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
HLDDABII_00983	7.16e-163	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
HLDDABII_00984	1.2e-107	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HLDDABII_00985	3.8e-196	-	-	-	EG	-	-	-	EamA-like transporter family
HLDDABII_00986	9.45e-152	-	-	-	L	-	-	-	Integrase
HLDDABII_00987	8.45e-203	rssA	-	-	S	-	-	-	Phospholipase, patatin family
HLDDABII_00988	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HLDDABII_00989	8.4e-259	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLDDABII_00991	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLDDABII_00992	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HLDDABII_00993	6.3e-225	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLDDABII_00994	5.94e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLDDABII_00995	2.28e-202	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HLDDABII_00996	6.06e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HLDDABII_00997	5.28e-281	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLDDABII_00998	2.08e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLDDABII_00999	4.61e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLDDABII_01000	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HLDDABII_01001	2.41e-183	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLDDABII_01002	1.14e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HLDDABII_01003	3.21e-167	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HLDDABII_01012	3.02e-59	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HLDDABII_01013	8.23e-39	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HLDDABII_01014	4.5e-73	-	-	-	-	-	-	-	-
HLDDABII_01015	5.88e-146	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HLDDABII_01016	7.05e-101	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLDDABII_01017	2.6e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLDDABII_01020	2.54e-60	yrvD	-	-	S	-	-	-	Pfam:DUF1049
HLDDABII_01021	4.68e-197	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HLDDABII_01022	8e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HLDDABII_01023	1.01e-28	-	-	-	-	-	-	-	-
HLDDABII_01024	3.46e-208	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLDDABII_01025	1.2e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HLDDABII_01026	1.36e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HLDDABII_01027	1.77e-54	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
HLDDABII_01028	1.09e-169	-	-	-	L	-	-	-	Transposase
HLDDABII_01029	1.9e-111	isp	-	-	L	-	-	-	Transposase
HLDDABII_01030	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLDDABII_01031	1.4e-201	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HLDDABII_01032	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HLDDABII_01034	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLDDABII_01035	7.36e-291	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HLDDABII_01036	2.04e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
HLDDABII_01037	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HLDDABII_01038	6.28e-73	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLDDABII_01039	1.3e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLDDABII_01040	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLDDABII_01041	2.37e-184	-	-	-	S	-	-	-	DUF218 domain
HLDDABII_01042	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HLDDABII_01043	5.51e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
HLDDABII_01044	2.39e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HLDDABII_01045	2.9e-309	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HLDDABII_01046	0.0	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLDDABII_01047	9.49e-98	-	-	-	S	-	-	-	UPF0756 membrane protein
HLDDABII_01048	6.14e-104	-	-	-	S	-	-	-	Cupin domain
HLDDABII_01049	3.4e-108	-	-	-	C	-	-	-	Flavodoxin
HLDDABII_01050	7.79e-204	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
HLDDABII_01051	2.99e-218	yvgN	-	-	C	-	-	-	Aldo keto reductase
HLDDABII_01052	7.35e-12	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HLDDABII_01053	7.87e-24	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HLDDABII_01054	1.43e-306	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HLDDABII_01055	7.5e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLDDABII_01056	5.98e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
HLDDABII_01057	2.07e-202	gspA	-	-	M	-	-	-	family 8
HLDDABII_01058	3.04e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLDDABII_01059	7.49e-124	-	-	-	-	-	-	-	-
HLDDABII_01060	1.2e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
HLDDABII_01061	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HLDDABII_01062	2e-301	isp	-	-	L	-	-	-	Transposase
HLDDABII_01063	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HLDDABII_01064	1.58e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HLDDABII_01065	5.61e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLDDABII_01066	1.92e-91	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLDDABII_01067	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HLDDABII_01068	4.44e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HLDDABII_01069	3.43e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HLDDABII_01070	1.01e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HLDDABII_01071	2.57e-75	-	-	-	-	-	-	-	-
HLDDABII_01072	7.16e-190	-	-	-	L	-	-	-	Transposase
HLDDABII_01073	3.33e-244	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_01074	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HLDDABII_01075	1.17e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HLDDABII_01076	7.01e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLDDABII_01077	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HLDDABII_01078	5.69e-207	-	-	-	EG	-	-	-	EamA-like transporter family
HLDDABII_01079	1.75e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HLDDABII_01080	9.09e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HLDDABII_01081	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HLDDABII_01082	2.1e-219	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HLDDABII_01083	1.71e-217	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HLDDABII_01084	4.11e-274	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HLDDABII_01085	8.91e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLDDABII_01086	5.52e-119	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HLDDABII_01087	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HLDDABII_01088	2.43e-241	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HLDDABII_01089	5.79e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HLDDABII_01090	1.97e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HLDDABII_01091	4.38e-161	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HLDDABII_01092	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HLDDABII_01093	8.31e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HLDDABII_01094	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
HLDDABII_01095	1.54e-191	-	-	-	O	-	-	-	Band 7 protein
HLDDABII_01096	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HLDDABII_01097	4.88e-200	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HLDDABII_01098	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
HLDDABII_01099	5.87e-147	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HLDDABII_01100	3.86e-205	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HLDDABII_01101	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HLDDABII_01102	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HLDDABII_01103	9.11e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HLDDABII_01104	1.35e-300	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLDDABII_01105	1.07e-301	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HLDDABII_01106	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HLDDABII_01107	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HLDDABII_01108	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HLDDABII_01109	5.19e-27	-	-	-	-	-	-	-	-
HLDDABII_01110	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HLDDABII_01111	2e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HLDDABII_01112	9.54e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
HLDDABII_01113	1.43e-141	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
HLDDABII_01114	3.07e-265	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HLDDABII_01115	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HLDDABII_01116	1e-143	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
HLDDABII_01117	2.72e-102	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HLDDABII_01118	7.55e-286	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HLDDABII_01119	3.39e-124	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HLDDABII_01120	5.59e-249	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HLDDABII_01121	7.54e-173	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLDDABII_01122	1.78e-74	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLDDABII_01123	2.7e-230	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HLDDABII_01125	1.83e-46	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLDDABII_01126	1.07e-148	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HLDDABII_01127	0.0	-	-	-	L	-	-	-	PLD-like domain
HLDDABII_01128	4.18e-236	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_01129	7.16e-47	higA	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein HigA
HLDDABII_01130	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HLDDABII_01131	1.26e-66	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type i restriction
HLDDABII_01132	1.68e-229	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLDDABII_01134	5.62e-59	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HLDDABII_01135	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HLDDABII_01136	7.54e-218	-	-	-	S	-	-	-	Protein of unknown function DUF262
HLDDABII_01137	7.48e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HLDDABII_01138	1.26e-60	-	-	-	-	-	-	-	-
HLDDABII_01139	1.81e-41	-	-	-	-	-	-	-	-
HLDDABII_01140	1.09e-62	-	-	-	-	-	-	-	-
HLDDABII_01141	2.93e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLDDABII_01142	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HLDDABII_01143	1.63e-296	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HLDDABII_01144	4.12e-234	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLDDABII_01145	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HLDDABII_01146	1.89e-123	-	-	-	-	-	-	-	-
HLDDABII_01147	3.09e-35	-	-	-	-	-	-	-	-
HLDDABII_01148	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HLDDABII_01149	7.63e-117	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HLDDABII_01151	1.12e-82	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLDDABII_01152	5.95e-118	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_01153	3.21e-164	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HLDDABII_01154	7.19e-152	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HLDDABII_01155	9.14e-66	-	-	-	-	-	-	-	-
HLDDABII_01156	2.49e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HLDDABII_01157	0.0	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLDDABII_01158	5.18e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HLDDABII_01159	2.41e-111	-	-	-	F	-	-	-	NUDIX domain
HLDDABII_01160	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLDDABII_01161	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLDDABII_01162	1.9e-139	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLDDABII_01163	7.89e-212	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HLDDABII_01164	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLDDABII_01165	7.84e-207	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HLDDABII_01166	2.05e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLDDABII_01167	1.99e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLDDABII_01168	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HLDDABII_01169	4.05e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HLDDABII_01170	4.79e-221	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HLDDABII_01171	7.45e-195	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HLDDABII_01172	2.59e-144	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HLDDABII_01173	3.38e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLDDABII_01174	3.61e-247	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLDDABII_01175	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HLDDABII_01176	8.18e-286	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLDDABII_01177	9.5e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HLDDABII_01178	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLDDABII_01179	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HLDDABII_01180	1e-272	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HLDDABII_01181	3.8e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HLDDABII_01182	2.15e-83	-	-	-	M	-	-	-	Lysin motif
HLDDABII_01183	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HLDDABII_01184	7.6e-246	-	-	-	S	-	-	-	Helix-turn-helix domain
HLDDABII_01185	2.65e-133	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLDDABII_01186	6.81e-163	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HLDDABII_01187	1.35e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLDDABII_01188	1.95e-177	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLDDABII_01189	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLDDABII_01190	2.35e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HLDDABII_01191	1.08e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HLDDABII_01192	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HLDDABII_01193	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HLDDABII_01194	1.16e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HLDDABII_01195	5.93e-179	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HLDDABII_01196	7.91e-40	-	-	-	S	-	-	-	COG5546 Small integral membrane protein
HLDDABII_01200	1.2e-08	-	-	-	S	-	-	-	glycerophosphodiester phosphodiesterase activity
HLDDABII_01205	1.08e-273	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
HLDDABII_01206	1.22e-173	-	-	-	S	-	-	-	Phage tail protein
HLDDABII_01207	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HLDDABII_01208	8.23e-28	-	-	-	-	-	-	-	-
HLDDABII_01210	3.87e-148	-	-	-	-	-	-	-	-
HLDDABII_01211	3.29e-99	-	-	-	-	-	-	-	-
HLDDABII_01212	1.85e-82	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HLDDABII_01213	4.51e-54	-	-	-	S	-	-	-	Phage head-tail joining protein
HLDDABII_01214	1.64e-89	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HLDDABII_01215	3.13e-202	-	-	-	S	-	-	-	Phage capsid family
HLDDABII_01216	3.4e-146	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HLDDABII_01217	1.12e-307	-	-	-	S	-	-	-	Phage portal protein
HLDDABII_01220	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HLDDABII_01221	1.62e-100	-	-	-	L	-	-	-	Phage terminase, small subunit
HLDDABII_01222	1.02e-194	-	-	-	L	-	-	-	HNH nucleases
HLDDABII_01225	4.19e-106	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
HLDDABII_01226	1.4e-30	-	-	-	-	-	-	-	-
HLDDABII_01228	2.04e-19	-	-	-	-	-	-	-	-
HLDDABII_01231	1.38e-75	-	-	-	S	-	-	-	VRR_NUC
HLDDABII_01233	1.42e-146	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
HLDDABII_01234	3.11e-80	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HLDDABII_01235	1.24e-18	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HLDDABII_01236	1.7e-38	-	-	-	-	-	-	-	-
HLDDABII_01238	2.68e-52	-	-	-	L	-	-	-	AAA domain
HLDDABII_01239	2.27e-24	-	-	-	L	-	-	-	AAA domain
HLDDABII_01240	1.2e-10	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HLDDABII_01241	1.04e-176	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HLDDABII_01242	1.11e-75	-	-	-	S	-	-	-	Siphovirus Gp157
HLDDABII_01243	1.33e-32	-	-	-	-	-	-	-	-
HLDDABII_01245	6.67e-43	-	-	-	-	-	-	-	-
HLDDABII_01250	3.22e-22	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLDDABII_01251	1.92e-60	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HLDDABII_01252	1.42e-100	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HLDDABII_01258	2.07e-116	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLDDABII_01259	5.8e-148	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HLDDABII_01260	7.91e-40	-	-	-	S	-	-	-	COG5546 Small integral membrane protein
HLDDABII_01264	4.44e-21	-	-	-	UW	-	-	-	CotH kinase protein
HLDDABII_01267	2.31e-279	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HLDDABII_01268	1.85e-201	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLDDABII_01269	2.2e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HLDDABII_01270	1.69e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLDDABII_01271	2.09e-265	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLDDABII_01272	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLDDABII_01273	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HLDDABII_01274	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HLDDABII_01275	2.14e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HLDDABII_01276	1.08e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLDDABII_01277	2.11e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HLDDABII_01278	1.55e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLDDABII_01279	2.6e-234	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HLDDABII_01280	4.11e-225	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLDDABII_01281	1.71e-119	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HLDDABII_01282	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HLDDABII_01283	2.42e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLDDABII_01284	1.2e-234	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLDDABII_01285	3.07e-240	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_01286	2.34e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HLDDABII_01287	8.25e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HLDDABII_01288	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HLDDABII_01289	6.06e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLDDABII_01290	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HLDDABII_01291	2.09e-211	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HLDDABII_01292	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLDDABII_01293	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLDDABII_01294	4.8e-72	-	-	-	-	-	-	-	-
HLDDABII_01295	1.66e-165	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLDDABII_01296	4.65e-229	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HLDDABII_01297	7.92e-76	-	-	-	-	-	-	-	-
HLDDABII_01299	4.78e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HLDDABII_01301	4.13e-254	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HLDDABII_01302	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLDDABII_01303	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLDDABII_01304	1.32e-125	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLDDABII_01305	1.07e-192	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLDDABII_01306	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLDDABII_01307	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HLDDABII_01308	5.24e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLDDABII_01309	1.13e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLDDABII_01310	1.79e-84	-	-	-	-	-	-	-	-
HLDDABII_01311	3.13e-225	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HLDDABII_01312	1.21e-215	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLDDABII_01313	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLDDABII_01314	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLDDABII_01315	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
HLDDABII_01316	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HLDDABII_01317	1.68e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HLDDABII_01318	1.1e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HLDDABII_01319	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLDDABII_01320	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLDDABII_01321	7.76e-297	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HLDDABII_01322	1.18e-177	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HLDDABII_01323	1.5e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLDDABII_01324	4.23e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLDDABII_01325	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HLDDABII_01326	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLDDABII_01327	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HLDDABII_01328	5.9e-233	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLDDABII_01329	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HLDDABII_01330	5.9e-182	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HLDDABII_01331	7.51e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HLDDABII_01332	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HLDDABII_01333	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
HLDDABII_01334	4.18e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLDDABII_01335	2.88e-270	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HLDDABII_01336	7.77e-159	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLDDABII_01345	5.17e-57	-	-	-	K	-	-	-	COG3617 Prophage antirepressor
HLDDABII_01346	5.38e-40	-	-	-	-	-	-	-	-
HLDDABII_01347	2.74e-19	-	-	-	-	-	-	-	-
HLDDABII_01348	2.14e-15	-	-	-	K	-	-	-	Transcriptional
HLDDABII_01349	2.28e-41	-	-	-	-	-	-	-	-
HLDDABII_01351	1.66e-87	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLDDABII_01352	3.76e-124	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLDDABII_01353	3.6e-41	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLDDABII_01355	3.21e-172	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLDDABII_01356	1.79e-121	-	-	-	-	-	-	-	-
HLDDABII_01357	1.46e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLDDABII_01358	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HLDDABII_01359	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLDDABII_01360	3.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLDDABII_01361	3.8e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLDDABII_01362	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLDDABII_01363	2.44e-20	-	-	-	-	-	-	-	-
HLDDABII_01364	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HLDDABII_01365	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HLDDABII_01366	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLDDABII_01367	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLDDABII_01368	1.27e-275	isp	-	-	L	-	-	-	Transposase
HLDDABII_01369	1.49e-134	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_01370	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLDDABII_01371	7.23e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
HLDDABII_01372	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLDDABII_01373	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLDDABII_01374	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HLDDABII_01375	9.21e-200	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HLDDABII_01376	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HLDDABII_01377	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HLDDABII_01378	1.38e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HLDDABII_01379	1.23e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HLDDABII_01380	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLDDABII_01381	6.8e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HLDDABII_01382	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HLDDABII_01383	7.54e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HLDDABII_01384	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HLDDABII_01385	3.52e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HLDDABII_01386	7.04e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HLDDABII_01387	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HLDDABII_01388	2.13e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLDDABII_01389	9.42e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HLDDABII_01390	2.44e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HLDDABII_01391	1.38e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLDDABII_01392	6.08e-102	-	-	-	-	-	-	-	-
HLDDABII_01393	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HLDDABII_01394	1.69e-229	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
HLDDABII_01395	4.37e-39	-	-	-	-	-	-	-	-
HLDDABII_01396	3.3e-265	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HLDDABII_01398	2.15e-75	-	-	-	-	-	-	-	-
HLDDABII_01399	7.55e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HLDDABII_01400	2.7e-280	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HLDDABII_01401	8.17e-104	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
HLDDABII_01402	2.58e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLDDABII_01403	1.62e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLDDABII_01404	1.43e-177	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLDDABII_01405	9.32e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLDDABII_01406	1.64e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HLDDABII_01407	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HLDDABII_01408	1.45e-314	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLDDABII_01409	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HLDDABII_01410	3.17e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HLDDABII_01411	1.4e-38	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HLDDABII_01412	1.79e-96	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HLDDABII_01413	2.5e-94	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HLDDABII_01414	3.1e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
HLDDABII_01415	8.58e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLDDABII_01416	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLDDABII_01417	3.82e-157	-	-	-	S	-	-	-	repeat protein
HLDDABII_01418	6.67e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HLDDABII_01419	2.15e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLDDABII_01420	1.13e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HLDDABII_01421	1.75e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HLDDABII_01422	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLDDABII_01423	1.54e-33	-	-	-	-	-	-	-	-
HLDDABII_01424	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HLDDABII_01425	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HLDDABII_01426	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLDDABII_01427	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HLDDABII_01428	8.04e-185	ylmH	-	-	S	-	-	-	S4 domain protein
HLDDABII_01429	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HLDDABII_01430	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLDDABII_01431	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLDDABII_01432	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLDDABII_01433	8.69e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLDDABII_01434	1.45e-260	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLDDABII_01435	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLDDABII_01436	7.73e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLDDABII_01437	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HLDDABII_01438	3.47e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HLDDABII_01439	9.31e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLDDABII_01440	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HLDDABII_01441	7.76e-74	-	-	-	-	-	-	-	-
HLDDABII_01442	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HLDDABII_01443	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HLDDABII_01444	1.53e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLDDABII_01445	8.5e-208	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HLDDABII_01446	6.56e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HLDDABII_01448	6.36e-75	-	-	-	-	-	-	-	-
HLDDABII_01449	1.74e-57	-	-	-	-	-	-	-	-
HLDDABII_01452	1.13e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLDDABII_01453	7.22e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLDDABII_01454	7.45e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HLDDABII_01455	1.4e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
HLDDABII_01456	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLDDABII_01457	2.41e-264	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HLDDABII_01458	3.28e-156	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HLDDABII_01459	2.02e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLDDABII_01460	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HLDDABII_01461	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HLDDABII_01462	4.29e-304	isp	-	-	L	-	-	-	Transposase
HLDDABII_01482	6.36e-75	-	-	-	-	-	-	-	-
HLDDABII_01485	1.83e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HLDDABII_01486	1.03e-135	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HLDDABII_01487	2.87e-171	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HLDDABII_01488	9.28e-121	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HLDDABII_01489	1.08e-146	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLDDABII_01490	4.18e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLDDABII_01491	2.07e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HLDDABII_01493	9.32e-92	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
HLDDABII_01494	1.61e-54	-	-	-	-	-	-	-	-
HLDDABII_01495	4.8e-99	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HLDDABII_01496	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HLDDABII_01497	4.8e-230	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HLDDABII_01498	4.67e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HLDDABII_01499	4.97e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HLDDABII_01500	1.15e-178	-	-	-	-	-	-	-	-
HLDDABII_01501	2.81e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HLDDABII_01502	1.08e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HLDDABII_01503	1.84e-75	-	-	-	-	-	-	-	-
HLDDABII_01504	8.88e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HLDDABII_01505	6.23e-188	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HLDDABII_01506	1.1e-195	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HLDDABII_01507	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
HLDDABII_01508	9.81e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HLDDABII_01509	3.33e-133	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLDDABII_01510	2.58e-184	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HLDDABII_01511	1.01e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HLDDABII_01512	8.12e-218	isp	-	-	L	-	-	-	Transposase
HLDDABII_01513	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HLDDABII_01514	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLDDABII_01515	8.35e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
HLDDABII_01516	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HLDDABII_01517	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLDDABII_01518	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HLDDABII_01519	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLDDABII_01520	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLDDABII_01521	6.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HLDDABII_01522	7.54e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HLDDABII_01523	1.25e-241	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HLDDABII_01524	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLDDABII_01525	1.51e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLDDABII_01526	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLDDABII_01527	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLDDABII_01528	7.49e-137	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_01529	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HLDDABII_01530	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HLDDABII_01531	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLDDABII_01532	1.13e-289	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HLDDABII_01533	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLDDABII_01534	2.06e-197	-	-	-	S	-	-	-	Helix-turn-helix domain
HLDDABII_01535	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HLDDABII_01536	1.75e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HLDDABII_01537	4.04e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HLDDABII_01538	2.06e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLDDABII_01539	4.45e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HLDDABII_01540	1.62e-118	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HLDDABII_01541	4.46e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HLDDABII_01542	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HLDDABII_01543	6.98e-156	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HLDDABII_01544	1.23e-311	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HLDDABII_01545	1.22e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HLDDABII_01546	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HLDDABII_01547	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HLDDABII_01548	6.92e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HLDDABII_01549	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HLDDABII_01550	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLDDABII_01551	5.83e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLDDABII_01552	2.48e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HLDDABII_01553	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLDDABII_01554	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLDDABII_01555	0.0	-	-	-	L	-	-	-	Transposase
HLDDABII_01556	2.56e-300	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HLDDABII_01557	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HLDDABII_01558	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HLDDABII_01559	8.18e-174	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HLDDABII_01560	4.73e-179	-	-	-	S	-	-	-	Membrane
HLDDABII_01561	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
HLDDABII_01562	9.79e-29	-	-	-	-	-	-	-	-
HLDDABII_01563	2.03e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HLDDABII_01564	3.8e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HLDDABII_01565	3.61e-61	-	-	-	-	-	-	-	-
HLDDABII_01566	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
HLDDABII_01567	8.8e-264	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HLDDABII_01568	3.44e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
HLDDABII_01569	3.47e-123	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HLDDABII_01570	2.08e-213	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HLDDABII_01571	6.29e-165	-	1.1.1.100, 1.1.1.69	-	I	ko:K00046,ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HLDDABII_01572	3.42e-46	-	-	-	-	-	-	-	-
HLDDABII_01573	7.51e-129	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLDDABII_01574	6.98e-137	-	-	-	L	-	-	-	Helix-turn-helix domain
HLDDABII_01575	2.48e-178	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HLDDABII_01576	5.21e-191	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLDDABII_01577	2.27e-147	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_01578	1.01e-79	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_01579	6.32e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HLDDABII_01580	1.17e-61	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HLDDABII_01581	3.86e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HLDDABII_01582	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HLDDABII_01583	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HLDDABII_01584	1.05e-308	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLDDABII_01585	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HLDDABII_01586	1.05e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HLDDABII_01587	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLDDABII_01588	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLDDABII_01589	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLDDABII_01590	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLDDABII_01591	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLDDABII_01592	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLDDABII_01593	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HLDDABII_01594	2.3e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HLDDABII_01595	4.71e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HLDDABII_01596	6.71e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HLDDABII_01597	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLDDABII_01598	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLDDABII_01599	6.33e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLDDABII_01600	1.55e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLDDABII_01601	1.86e-208	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLDDABII_01602	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLDDABII_01603	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HLDDABII_01604	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HLDDABII_01605	4.87e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HLDDABII_01606	1.97e-297	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
HLDDABII_01607	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HLDDABII_01608	1.77e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HLDDABII_01609	1.25e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HLDDABII_01610	9.5e-239	ampC	-	-	V	-	-	-	Beta-lactamase
HLDDABII_01611	2.01e-76	-	-	-	-	-	-	-	-
HLDDABII_01612	0.0	-	-	-	M	-	-	-	domain protein
HLDDABII_01613	3.75e-137	-	-	-	-	-	-	-	-
HLDDABII_01614	2.49e-169	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLDDABII_01616	1.38e-09	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLDDABII_01617	2.86e-19	-	-	-	S	-	-	-	Helix-turn-helix domain
HLDDABII_01618	1.17e-53	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
HLDDABII_01619	7.68e-07	-	-	-	S	-	-	-	Helix-turn-helix domain
HLDDABII_01626	1.11e-05	-	-	-	-	-	-	-	-
HLDDABII_01632	1.06e-64	-	-	-	-	-	-	-	-
HLDDABII_01634	0.0	-	-	-	D	-	-	-	domain protein
HLDDABII_01637	1.09e-200	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HLDDABII_01638	2.2e-68	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HLDDABII_01640	2.13e-74	-	-	-	-	-	-	-	-
HLDDABII_01642	2.05e-109	-	-	-	-	-	-	-	-
HLDDABII_01643	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HLDDABII_01644	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
HLDDABII_01645	1.6e-82	-	-	-	S	-	-	-	Cupredoxin-like domain
HLDDABII_01646	7.03e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HLDDABII_01647	3.18e-206	-	-	-	EG	-	-	-	EamA-like transporter family
HLDDABII_01648	3.94e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HLDDABII_01649	3.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLDDABII_01650	3.05e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
HLDDABII_01651	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HLDDABII_01652	4.66e-123	xylR	-	-	GK	-	-	-	ROK family
HLDDABII_01653	5.79e-217	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HLDDABII_01654	8.22e-29	xylR	-	-	GK	-	-	-	ROK family
HLDDABII_01655	2.49e-39	-	-	-	-	-	-	-	-
HLDDABII_01656	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HLDDABII_01657	4.34e-138	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HLDDABII_01658	2.71e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HLDDABII_01659	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HLDDABII_01660	2.7e-172	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HLDDABII_01662	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
HLDDABII_01663	4.01e-193	-	-	-	S	-	-	-	Cof-like hydrolase
HLDDABII_01664	3.7e-106	-	-	-	K	-	-	-	Transcriptional regulator
HLDDABII_01665	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HLDDABII_01666	5.17e-70	-	-	-	-	-	-	-	-
HLDDABII_01667	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLDDABII_01668	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLDDABII_01669	7.48e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
HLDDABII_01670	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLDDABII_01671	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HLDDABII_01672	1.43e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HLDDABII_01673	1.31e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLDDABII_01674	6.77e-216	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HLDDABII_01675	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HLDDABII_01676	3.55e-99	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HLDDABII_01677	1.46e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLDDABII_01678	6.95e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HLDDABII_01679	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HLDDABII_01680	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLDDABII_01681	9.61e-137	-	-	-	-	-	-	-	-
HLDDABII_01682	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HLDDABII_01683	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLDDABII_01684	3.29e-187	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HLDDABII_01685	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HLDDABII_01686	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HLDDABII_01687	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HLDDABII_01688	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLDDABII_01689	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLDDABII_01690	1.08e-289	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HLDDABII_01691	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLDDABII_01693	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLDDABII_01694	1.83e-21	-	-	-	-	-	-	-	-
HLDDABII_01696	1.94e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HLDDABII_01697	5.73e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HLDDABII_01698	8.05e-208	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HLDDABII_01699	5.51e-316	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HLDDABII_01700	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLDDABII_01701	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLDDABII_01702	4.16e-19	-	-	-	-	-	-	-	-
HLDDABII_01703	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HLDDABII_01704	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HLDDABII_01705	2.85e-114	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HLDDABII_01706	5.89e-201	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
HLDDABII_01707	1.9e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HLDDABII_01708	2.38e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLDDABII_01709	1.43e-208	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HLDDABII_01710	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HLDDABII_01711	5.04e-175	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HLDDABII_01712	1.79e-214	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HLDDABII_01713	5.93e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HLDDABII_01714	3.31e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLDDABII_01715	2.79e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLDDABII_01716	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HLDDABII_01717	2.11e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HLDDABII_01718	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLDDABII_01719	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLDDABII_01720	5e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLDDABII_01721	1.73e-148	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HLDDABII_01722	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HLDDABII_01723	6.65e-145	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HLDDABII_01724	1.58e-301	-	-	-	EGP	-	-	-	Major Facilitator
HLDDABII_01725	8.81e-89	-	-	-	K	-	-	-	Transcriptional regulator
HLDDABII_01726	2.63e-53	-	-	-	-	-	-	-	-
HLDDABII_01727	0.0	ydaO	-	-	E	-	-	-	amino acid
HLDDABII_01728	0.0	-	-	-	E	-	-	-	amino acid
HLDDABII_01729	3.11e-106	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
HLDDABII_01730	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLDDABII_01731	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLDDABII_01733	1.34e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLDDABII_01734	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HLDDABII_01735	1.39e-231	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLDDABII_01736	6.98e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLDDABII_01737	6.34e-182	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HLDDABII_01738	4.25e-176	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLDDABII_01739	6.3e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLDDABII_01740	2.55e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLDDABII_01741	2.12e-253	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLDDABII_01742	3.02e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HLDDABII_01743	1.27e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HLDDABII_01744	6.02e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HLDDABII_01745	1.87e-221	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HLDDABII_01746	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HLDDABII_01747	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HLDDABII_01748	6.09e-176	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HLDDABII_01749	3.7e-199	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLDDABII_01750	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HLDDABII_01751	1.29e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HLDDABII_01752	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HLDDABII_01753	2.14e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLDDABII_01754	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HLDDABII_01755	1.41e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLDDABII_01756	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLDDABII_01757	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLDDABII_01758	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLDDABII_01759	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HLDDABII_01760	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLDDABII_01761	4.63e-255	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLDDABII_01762	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HLDDABII_01763	9.19e-78	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HLDDABII_01764	8.89e-17	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HLDDABII_01765	1.89e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HLDDABII_01766	2.79e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HLDDABII_01767	4.66e-49	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLDDABII_01769	2.91e-65	-	-	-	-	-	-	-	-
HLDDABII_01770	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLDDABII_01771	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLDDABII_01772	3.25e-162	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLDDABII_01773	3.88e-76	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLDDABII_01774	1.28e-311	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HLDDABII_01776	1.86e-288	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HLDDABII_01777	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLDDABII_01778	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLDDABII_01779	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HLDDABII_01780	2.9e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLDDABII_01781	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HLDDABII_01782	1.05e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLDDABII_01783	3.58e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLDDABII_01784	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HLDDABII_01785	5.12e-266	yacL	-	-	S	-	-	-	domain protein
HLDDABII_01786	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLDDABII_01787	1.1e-125	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HLDDABII_01788	3.33e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HLDDABII_01789	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HLDDABII_01790	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HLDDABII_01791	3.51e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HLDDABII_01792	2.38e-171	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLDDABII_01793	9.62e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLDDABII_01794	2.47e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HLDDABII_01795	6.27e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLDDABII_01796	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLDDABII_01797	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HLDDABII_01798	5.27e-235	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HLDDABII_01799	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HLDDABII_01801	2.34e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HLDDABII_01802	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HLDDABII_01803	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLDDABII_01804	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLDDABII_01805	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HLDDABII_01806	1.1e-171	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HLDDABII_01807	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HLDDABII_01808	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HLDDABII_01809	1.81e-142	-	-	-	-	-	-	-	-
HLDDABII_01812	1.85e-202	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLDDABII_01813	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HLDDABII_01816	9.11e-114	-	-	-	C	-	-	-	Oxidoreductase
HLDDABII_01817	3.41e-27	-	-	-	C	-	-	-	Oxidoreductase
HLDDABII_01818	2.89e-68	-	-	-	C	-	-	-	Oxidoreductase
HLDDABII_01819	3.88e-71	-	-	-	S	-	-	-	macrophage migration inhibitory factor
HLDDABII_01820	4.95e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HLDDABII_01821	2.09e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLDDABII_01823	3.01e-285	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HLDDABII_01824	1.41e-147	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLDDABII_01825	6.39e-168	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLDDABII_01827	4.48e-73	-	-	-	-	-	-	-	-
HLDDABII_01828	5.72e-104	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLDDABII_01829	6.86e-103	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_01830	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
HLDDABII_01831	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HLDDABII_01832	1.53e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLDDABII_01833	7.93e-219	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLDDABII_01834	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLDDABII_01835	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HLDDABII_01836	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLDDABII_01837	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HLDDABII_01838	7.15e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HLDDABII_01839	1.18e-51	yabO	-	-	J	-	-	-	S4 domain protein
HLDDABII_01840	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLDDABII_01841	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLDDABII_01842	2.7e-145	-	-	-	S	-	-	-	(CBS) domain
HLDDABII_01843	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HLDDABII_01844	2.75e-309	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
HLDDABII_01845	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HLDDABII_01846	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HLDDABII_01847	1.54e-269	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLDDABII_01848	1.88e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLDDABII_01849	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HLDDABII_01850	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDDABII_01851	1.23e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HLDDABII_01852	4.1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDDABII_01853	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLDDABII_01854	4.83e-212	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HLDDABII_01855	4.84e-241	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HLDDABII_01856	2.29e-158	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLDDABII_01857	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLDDABII_01858	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLDDABII_01859	1.06e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HLDDABII_01860	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HLDDABII_01861	2.71e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLDDABII_01862	1.51e-154	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HLDDABII_01863	9.18e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HLDDABII_01864	6.08e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLDDABII_01865	8.67e-289	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HLDDABII_01866	4.29e-162	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HLDDABII_01867	1.86e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLDDABII_01868	3.07e-301	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLDDABII_01869	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HLDDABII_01870	5.29e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLDDABII_01871	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLDDABII_01872	6e-85	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLDDABII_01873	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HLDDABII_01874	4.82e-188	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HLDDABII_01875	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HLDDABII_01876	1.89e-189	yidA	-	-	S	-	-	-	hydrolase
HLDDABII_01877	1.6e-100	-	-	-	-	-	-	-	-
HLDDABII_01878	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLDDABII_01879	1.29e-313	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLDDABII_01880	5.24e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HLDDABII_01881	4.12e-164	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HLDDABII_01882	1.9e-155	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HLDDABII_01883	1.66e-214	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HLDDABII_01884	5.5e-203	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HLDDABII_01885	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HLDDABII_01886	9.83e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLDDABII_01887	6.03e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLDDABII_01888	5.3e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HLDDABII_01889	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLDDABII_01890	4.74e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HLDDABII_01892	5.9e-168	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HLDDABII_01893	1.09e-227	-	-	-	-	-	-	-	-
HLDDABII_01894	2.08e-283	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HLDDABII_01895	2.53e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HLDDABII_01896	5.54e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HLDDABII_01897	5.96e-241	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HLDDABII_01898	7.04e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HLDDABII_01899	0.0	-	-	-	L	-	-	-	DNA helicase
HLDDABII_01900	3.16e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLDDABII_01902	8.05e-186	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLDDABII_01903	2.48e-116	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLDDABII_01904	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HLDDABII_01905	5.71e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLDDABII_01906	1.41e-53	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
HLDDABII_01907	2.31e-278	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HLDDABII_01908	1.65e-112	isp	-	-	L	-	-	-	Transposase
HLDDABII_01909	4.67e-18	-	-	-	L	-	-	-	Transposase
HLDDABII_01910	1.74e-132	-	-	-	L	-	-	-	Transposase
HLDDABII_01911	5.14e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HLDDABII_01912	4.16e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HLDDABII_01913	7e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLDDABII_01914	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLDDABII_01915	1.96e-275	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HLDDABII_01916	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HLDDABII_01917	3.53e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HLDDABII_01918	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HLDDABII_01919	1.01e-180	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDDABII_01920	2.35e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLDDABII_01921	1.77e-207	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
HLDDABII_01922	2.24e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HLDDABII_01923	5.25e-197	-	-	-	GM	-	-	-	NAD(P)H-binding
HLDDABII_01924	4.44e-11	-	-	-	-	-	-	-	-
HLDDABII_01925	5.23e-276	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
HLDDABII_01926	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HLDDABII_01927	1.31e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HLDDABII_01928	6.35e-55	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_01929	6.52e-63	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_01930	3.63e-82	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_01931	7.41e-163	-	-	-	-	-	-	-	-
HLDDABII_01932	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HLDDABII_01933	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HLDDABII_01935	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HLDDABII_01936	4.51e-101	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
HLDDABII_01937	5.2e-225	ydhF	-	-	S	-	-	-	Aldo keto reductase
HLDDABII_01938	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HLDDABII_01939	1.53e-110	-	-	-	S	-	-	-	Membrane
HLDDABII_01940	9.23e-185	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HLDDABII_01942	1.79e-133	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_01943	1.68e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLDDABII_01944	1.26e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HLDDABII_01945	2.14e-133	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HLDDABII_01947	1.82e-78	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLDDABII_01948	4.57e-137	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLDDABII_01949	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HLDDABII_01950	2.69e-51	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
HLDDABII_01951	1.63e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HLDDABII_01952	3.88e-50	-	-	-	-	-	-	-	-
HLDDABII_01953	1.13e-129	-	-	-	IQ	-	-	-	dehydrogenase reductase
HLDDABII_01954	5.79e-217	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HLDDABII_01955	3.31e-98	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_01956	2.4e-126	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_01957	2.08e-158	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
HLDDABII_01958	4.48e-90	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HLDDABII_01959	3.35e-59	-	-	-	S	-	-	-	Pfam:DUF59
HLDDABII_01960	4.01e-216	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HLDDABII_01961	2.59e-135	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_01962	3.33e-149	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLDDABII_01969	2.1e-166	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HLDDABII_01971	2.98e-08	-	3.2.1.4	GH5,GH9	M	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	domain protein
HLDDABII_01972	2.59e-135	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_01973	2.24e-110	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HLDDABII_01974	5.74e-160	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HLDDABII_01975	3.58e-253	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HLDDABII_01976	1.06e-25	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
HLDDABII_01977	1.93e-101	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLDDABII_01978	1.25e-192	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HLDDABII_01979	4.66e-126	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLDDABII_01980	1.41e-07	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HLDDABII_01986	6.36e-73	-	-	-	-	-	-	-	-
HLDDABII_01987	4.92e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLDDABII_01988	7.38e-232	-	-	-	-	-	-	-	-
HLDDABII_01989	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLDDABII_01990	4.57e-307	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HLDDABII_01991	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HLDDABII_01992	8.26e-136	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HLDDABII_01993	5.37e-248	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HLDDABII_01994	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLDDABII_01995	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLDDABII_01996	1.15e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLDDABII_01997	2.23e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLDDABII_01998	2.13e-169	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HLDDABII_01999	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HLDDABII_02000	1.61e-271	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HLDDABII_02001	3.65e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLDDABII_02002	9.77e-170	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HLDDABII_02003	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HLDDABII_02004	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HLDDABII_02005	1.12e-225	ydbI	-	-	K	-	-	-	AI-2E family transporter
HLDDABII_02006	9.43e-301	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HLDDABII_02007	4.34e-121	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HLDDABII_02008	6.4e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HLDDABII_02009	1.83e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLDDABII_02010	1.61e-166	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLDDABII_02011	1.6e-219	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLDDABII_02012	4.45e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLDDABII_02013	6.04e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HLDDABII_02014	2.79e-179	-	-	-	K	-	-	-	LysR substrate binding domain
HLDDABII_02015	2.19e-63	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HLDDABII_02016	1.14e-37	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HLDDABII_02017	1.06e-83	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HLDDABII_02018	4.98e-89	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HLDDABII_02019	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
HLDDABII_02020	4.95e-195	-	-	-	E	-	-	-	AzlC protein
HLDDABII_02021	5.47e-261	hpk31	-	-	T	-	-	-	Histidine kinase
HLDDABII_02022	3.27e-159	vanR	-	-	K	-	-	-	response regulator
HLDDABII_02023	8.13e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLDDABII_02024	1.32e-219	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HLDDABII_02025	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HLDDABII_02026	1.58e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HLDDABII_02027	1.09e-296	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HLDDABII_02028	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HLDDABII_02029	7.35e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HLDDABII_02030	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLDDABII_02031	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HLDDABII_02032	4.83e-198	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HLDDABII_02033	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HLDDABII_02034	3.73e-200	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HLDDABII_02035	6.29e-163	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HLDDABII_02036	5.97e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HLDDABII_02037	2.76e-217	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HLDDABII_02038	1.14e-276	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
HLDDABII_02039	6.17e-286	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HLDDABII_02041	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLDDABII_02042	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLDDABII_02043	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLDDABII_02044	3.17e-202	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HLDDABII_02045	1.62e-117	-	-	-	L	-	-	-	Helix-turn-helix domain
HLDDABII_02046	1.08e-05	-	-	-	L	-	-	-	Helix-turn-helix domain
HLDDABII_02047	1.26e-243	flp	-	-	V	-	-	-	Beta-lactamase
HLDDABII_02048	7.15e-122	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HLDDABII_02049	5.66e-158	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HLDDABII_02050	1.84e-50	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HLDDABII_02051	1.08e-89	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HLDDABII_02052	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome
HLDDABII_02053	4.91e-302	isp	-	-	L	-	-	-	Transposase
HLDDABII_02054	3.17e-18	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
HLDDABII_02055	4.47e-74	-	-	-	K	-	-	-	Aminotransferase class I and II
HLDDABII_02056	2.19e-193	-	-	-	K	-	-	-	Aminotransferase class I and II
HLDDABII_02057	0.0	-	-	-	S	-	-	-	amidohydrolase
HLDDABII_02058	5.13e-71	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_02059	3.35e-102	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLDDABII_02061	1.65e-206	-	-	-	S	-	-	-	reductase
HLDDABII_02062	4.4e-114	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
HLDDABII_02063	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLDDABII_02064	7.33e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HLDDABII_02065	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLDDABII_02066	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HLDDABII_02067	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLDDABII_02068	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLDDABII_02069	2.55e-169	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HLDDABII_02070	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLDDABII_02071	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLDDABII_02072	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HLDDABII_02073	1.64e-39	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_02076	1.97e-82	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLDDABII_02077	1.28e-112	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLDDABII_02078	3.01e-285	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HLDDABII_02079	6.61e-26	-	-	-	-	-	-	-	-
HLDDABII_02080	3.3e-192	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HLDDABII_02081	9.48e-57	-	-	-	-	-	-	-	-
HLDDABII_02085	1.27e-245	-	-	-	S	-	-	-	Protein of unknown function DUF262
HLDDABII_02086	2.45e-23	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_02090	2.47e-230	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HLDDABII_02092	2.59e-135	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_02094	1.37e-30	-	-	-	S	-	-	-	regulation of transcription, DNA-dependent
HLDDABII_02097	4.66e-55	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HLDDABII_02098	7.99e-55	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HLDDABII_02099	1.37e-51	-	-	-	L	-	-	-	Integrase
HLDDABII_02100	4.71e-30	cadD	-	-	P	-	-	-	Cadmium resistance transporter
HLDDABII_02101	7.5e-75	cadD	-	-	P	-	-	-	Cadmium resistance transporter
HLDDABII_02102	6.81e-43	-	-	-	-	-	-	-	-
HLDDABII_02103	4.3e-87	-	-	-	L	-	-	-	Transposase
HLDDABII_02104	6.78e-56	isp	-	-	L	-	-	-	Transposase
HLDDABII_02105	1.81e-94	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HLDDABII_02106	1.61e-59	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HLDDABII_02107	4.55e-83	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HLDDABII_02108	8.52e-66	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HLDDABII_02109	2.08e-08	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLDDABII_02110	6.95e-51	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	Bacterial regulatory protein, arsR family
HLDDABII_02111	8.98e-54	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLDDABII_02112	1.4e-229	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
HLDDABII_02113	4.77e-48	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HLDDABII_02115	4.88e-83	repB	-	-	L	-	-	-	Initiator Replication protein
HLDDABII_02116	4.01e-268	-	-	-	-	-	-	-	-
HLDDABII_02118	2.1e-50	-	-	-	K	-	-	-	Helix-turn-helix domain
HLDDABII_02119	2.2e-70	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HLDDABII_02120	3.3e-124	-	-	-	L	-	-	-	Integrase
HLDDABII_02121	9.52e-56	-	-	-	L	ko:K07483	-	ko00000	Transposase
HLDDABII_02122	3.74e-109	-	-	-	D	-	-	-	AAA domain
HLDDABII_02123	1.1e-50	-	-	-	-	-	-	-	-
HLDDABII_02126	5.86e-311	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Tetracycline resistance protein TetA
HLDDABII_02127	9.53e-27	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HLDDABII_02128	5.1e-159	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_02129	3.2e-23	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_02130	5.65e-98	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HLDDABII_02131	4.78e-299	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HLDDABII_02132	4.14e-31	-	-	-	-	-	-	-	-
HLDDABII_02136	5.93e-16	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
HLDDABII_02141	1.1e-07	-	-	-	D	-	-	-	cell division
HLDDABII_02143	1.66e-90	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HLDDABII_02147	2.01e-13	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLDDABII_02150	6.94e-237	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_02151	9.96e-28	-	-	-	L	-	-	-	Participates in initiation and elongation during chromosome replication
HLDDABII_02152	5.22e-186	-	-	-	S	-	-	-	Terminase-like family
HLDDABII_02154	7.3e-60	-	-	-	-	-	-	-	-
HLDDABII_02156	1.23e-32	-	-	-	-	-	-	-	-
HLDDABII_02157	8.28e-113	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_02158	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HLDDABII_02159	7.4e-230	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HLDDABII_02160	1.87e-73	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HLDDABII_02161	1.74e-190	-	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HLDDABII_02162	6.94e-237	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_02163	3.63e-40	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
HLDDABII_02164	3.22e-46	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HLDDABII_02165	9.31e-51	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HLDDABII_02166	8.22e-217	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLDDABII_02167	4.66e-43	tnp2	-	-	L	ko:K07485	-	ko00000	Transposase
HLDDABII_02168	2.65e-271	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HLDDABII_02169	4.8e-90	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLDDABII_02170	9.36e-42	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HLDDABII_02171	2.72e-128	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HLDDABII_02173	7.63e-179	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLDDABII_02174	2.26e-102	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLDDABII_02175	3.34e-215	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HLDDABII_02176	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HLDDABII_02177	2.41e-148	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HLDDABII_02178	3.33e-38	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HLDDABII_02179	1.84e-57	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLDDABII_02180	3.07e-303	-	-	-	L	-	-	-	Transposase
HLDDABII_02181	1.07e-178	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_02182	1.05e-105	-	-	-	L	-	-	-	Integrase
HLDDABII_02186	9.36e-20	-	-	-	-	-	-	-	-
HLDDABII_02188	3.21e-268	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HLDDABII_02189	6.47e-88	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HLDDABII_02191	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HLDDABII_02197	1.66e-72	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HLDDABII_02198	1.22e-68	-	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HLDDABII_02199	1.52e-103	-	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HLDDABII_02200	1.28e-32	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HLDDABII_02201	0.0	XK27_03440	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HLDDABII_02202	1.93e-300	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
HLDDABII_02203	3.51e-21	-	-	-	-	-	-	-	-
HLDDABII_02204	1.36e-243	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLDDABII_02205	1.05e-52	-	-	-	L	-	-	-	helicase
HLDDABII_02208	1.96e-134	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLDDABII_02209	4.85e-05	-	-	-	S	-	-	-	Short C-terminal domain
HLDDABII_02211	1.46e-26	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLDDABII_02218	1.06e-29	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLDDABII_02227	1.35e-33	-	-	-	-	-	-	-	-