ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
IPHOHMKD_00001 8.95e-315 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IPHOHMKD_00002 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IPHOHMKD_00003 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
IPHOHMKD_00004 2.07e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IPHOHMKD_00005 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPHOHMKD_00006 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPHOHMKD_00007 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
IPHOHMKD_00008 1.59e-95 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IPHOHMKD_00009 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPHOHMKD_00010 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
IPHOHMKD_00011 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
IPHOHMKD_00012 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
IPHOHMKD_00013 4.96e-289 yttB - - EGP - - - Major Facilitator
IPHOHMKD_00014 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IPHOHMKD_00015 1.88e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IPHOHMKD_00017 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
IPHOHMKD_00018 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IPHOHMKD_00019 7.76e-281 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IPHOHMKD_00020 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
IPHOHMKD_00021 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
IPHOHMKD_00022 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IPHOHMKD_00023 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
IPHOHMKD_00025 8.38e-184 - - - S - - - haloacid dehalogenase-like hydrolase
IPHOHMKD_00026 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
IPHOHMKD_00027 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
IPHOHMKD_00028 2.54e-43 - - - S - - - Pyridoxamine 5'-phosphate oxidase
IPHOHMKD_00029 5.31e-28 - - - S - - - Pyridoxamine 5'-phosphate oxidase
IPHOHMKD_00030 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
IPHOHMKD_00031 2.54e-50 - - - - - - - -
IPHOHMKD_00033 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
IPHOHMKD_00034 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IPHOHMKD_00035 3.55e-313 yycH - - S - - - YycH protein
IPHOHMKD_00036 3.54e-195 yycI - - S - - - YycH protein
IPHOHMKD_00037 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
IPHOHMKD_00038 1.1e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
IPHOHMKD_00039 2.39e-226 - - - L - - - Transposase and inactivated derivatives, IS30 family
IPHOHMKD_00040 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IPHOHMKD_00041 8.14e-123 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_00042 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
IPHOHMKD_00043 8.48e-215 - - - L - - - Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IPHOHMKD_00044 5.97e-157 ung2 - - L - - - Uracil-DNA glycosylase
IPHOHMKD_00045 8.12e-158 pnb - - C - - - nitroreductase
IPHOHMKD_00046 4.95e-86 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
IPHOHMKD_00047 1.57e-150 - - - S - - - Elongation factor G-binding protein, N-terminal
IPHOHMKD_00048 1.98e-164 - - - C - - - FMN_bind
IPHOHMKD_00049 0.0 - - - C - - - FMN_bind
IPHOHMKD_00050 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
IPHOHMKD_00051 5.93e-204 - - - K - - - LysR family
IPHOHMKD_00052 2.49e-95 - - - C - - - FMN binding
IPHOHMKD_00053 4.48e-98 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPHOHMKD_00054 4.06e-211 - - - S - - - KR domain
IPHOHMKD_00055 5.74e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
IPHOHMKD_00056 1.7e-155 ydgI - - C - - - Nitroreductase family
IPHOHMKD_00057 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
IPHOHMKD_00058 1.56e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
IPHOHMKD_00059 2.66e-249 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IPHOHMKD_00060 1.86e-316 - - - S - - - Putative threonine/serine exporter
IPHOHMKD_00061 5.64e-174 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
IPHOHMKD_00062 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
IPHOHMKD_00063 1.36e-105 - - - S - - - ASCH
IPHOHMKD_00064 1.25e-164 - - - F - - - glutamine amidotransferase
IPHOHMKD_00065 1.67e-220 - - - K - - - WYL domain
IPHOHMKD_00066 1.63e-152 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPHOHMKD_00067 0.0 fusA1 - - J - - - elongation factor G
IPHOHMKD_00068 7.74e-162 - - - S - - - Protein of unknown function
IPHOHMKD_00069 8.28e-193 - - - EG - - - EamA-like transporter family
IPHOHMKD_00070 1.08e-113 yfbM - - K - - - FR47-like protein
IPHOHMKD_00071 1.4e-162 - - - S - - - DJ-1/PfpI family
IPHOHMKD_00072 3.66e-229 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
IPHOHMKD_00073 1.92e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IPHOHMKD_00074 5.98e-302 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
IPHOHMKD_00075 5.57e-214 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
IPHOHMKD_00076 4.49e-180 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
IPHOHMKD_00077 2.38e-99 - - - - - - - -
IPHOHMKD_00078 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
IPHOHMKD_00079 3.42e-180 - - - - - - - -
IPHOHMKD_00080 4.07e-05 - - - - - - - -
IPHOHMKD_00081 1.1e-152 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
IPHOHMKD_00082 1.67e-54 - - - - - - - -
IPHOHMKD_00083 4.29e-166 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IPHOHMKD_00084 9.79e-192 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
IPHOHMKD_00085 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
IPHOHMKD_00086 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
IPHOHMKD_00087 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
IPHOHMKD_00088 3.03e-157 larB - - S ko:K06898 - ko00000 AIR carboxylase
IPHOHMKD_00089 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
IPHOHMKD_00090 6.32e-99 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
IPHOHMKD_00091 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IPHOHMKD_00092 3.03e-192 larE - - S ko:K06864 - ko00000 NAD synthase
IPHOHMKD_00093 9.67e-225 - - - C - - - Zinc-binding dehydrogenase
IPHOHMKD_00094 3.77e-175 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IPHOHMKD_00095 3.03e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IPHOHMKD_00096 2.68e-143 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IPHOHMKD_00097 2.4e-260 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
IPHOHMKD_00098 1.02e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
IPHOHMKD_00099 0.0 - - - L - - - HIRAN domain
IPHOHMKD_00100 1.24e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
IPHOHMKD_00101 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
IPHOHMKD_00102 5.18e-159 - - - - - - - -
IPHOHMKD_00103 2.07e-191 - - - I - - - Alpha/beta hydrolase family
IPHOHMKD_00104 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
IPHOHMKD_00105 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
IPHOHMKD_00106 2.01e-141 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
IPHOHMKD_00107 1.27e-98 - - - K - - - Transcriptional regulator
IPHOHMKD_00108 3.99e-96 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IPHOHMKD_00109 1.3e-104 - - - S - - - Protein of unknown function (DUF3021)
IPHOHMKD_00110 6.13e-99 - - - K - - - LytTr DNA-binding domain
IPHOHMKD_00111 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
IPHOHMKD_00112 3.98e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IPHOHMKD_00113 1.61e-273 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
IPHOHMKD_00115 4.36e-204 morA - - S - - - reductase
IPHOHMKD_00116 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
IPHOHMKD_00117 7.84e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
IPHOHMKD_00118 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
IPHOHMKD_00119 4.03e-132 - - - - - - - -
IPHOHMKD_00120 0.0 - - - - - - - -
IPHOHMKD_00121 6.49e-268 - - - C - - - Oxidoreductase
IPHOHMKD_00122 7.71e-192 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
IPHOHMKD_00123 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_00124 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
IPHOHMKD_00126 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
IPHOHMKD_00127 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
IPHOHMKD_00128 3.01e-180 - - - - - - - -
IPHOHMKD_00129 1.1e-191 - - - - - - - -
IPHOHMKD_00130 3.37e-115 - - - - - - - -
IPHOHMKD_00131 7.14e-185 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
IPHOHMKD_00132 1.22e-217 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IPHOHMKD_00133 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
IPHOHMKD_00134 8.03e-151 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
IPHOHMKD_00135 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
IPHOHMKD_00136 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
IPHOHMKD_00138 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_00139 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
IPHOHMKD_00140 2.24e-238 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
IPHOHMKD_00141 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
IPHOHMKD_00142 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
IPHOHMKD_00143 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IPHOHMKD_00144 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
IPHOHMKD_00145 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
IPHOHMKD_00146 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
IPHOHMKD_00147 9.45e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IPHOHMKD_00148 1.52e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IPHOHMKD_00149 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IPHOHMKD_00150 1.01e-190 malA - - S - - - maltodextrose utilization protein MalA
IPHOHMKD_00151 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
IPHOHMKD_00152 5.75e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IPHOHMKD_00153 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
IPHOHMKD_00154 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
IPHOHMKD_00155 8.23e-61 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
IPHOHMKD_00156 1.54e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
IPHOHMKD_00157 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
IPHOHMKD_00158 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IPHOHMKD_00159 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IPHOHMKD_00160 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
IPHOHMKD_00161 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
IPHOHMKD_00162 1.16e-210 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
IPHOHMKD_00163 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
IPHOHMKD_00164 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
IPHOHMKD_00165 1.72e-212 mleR - - K - - - LysR substrate binding domain
IPHOHMKD_00166 0.0 - - - M - - - domain protein
IPHOHMKD_00168 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
IPHOHMKD_00169 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
IPHOHMKD_00170 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
IPHOHMKD_00171 5.35e-102 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IPHOHMKD_00172 2.92e-278 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPHOHMKD_00173 2.92e-258 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IPHOHMKD_00174 9.51e-148 pgm1 - - G - - - phosphoglycerate mutase
IPHOHMKD_00175 2.49e-229 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
IPHOHMKD_00176 6.33e-46 - - - - - - - -
IPHOHMKD_00177 1.15e-79 - - - S - - - Domain of unknown function (DU1801)
IPHOHMKD_00178 1.46e-206 fbpA - - K - - - Domain of unknown function (DUF814)
IPHOHMKD_00179 1.29e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPHOHMKD_00180 3.81e-18 - - - - - - - -
IPHOHMKD_00181 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPHOHMKD_00182 2.31e-73 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPHOHMKD_00183 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
IPHOHMKD_00184 1.5e-150 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
IPHOHMKD_00185 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IPHOHMKD_00186 2.02e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
IPHOHMKD_00187 6.07e-117 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
IPHOHMKD_00188 5.3e-202 dkgB - - S - - - reductase
IPHOHMKD_00189 1.28e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IPHOHMKD_00190 1.2e-91 - - - - - - - -
IPHOHMKD_00191 2.32e-43 ygzD - - K ko:K07729 - ko00000,ko03000 Transcriptional
IPHOHMKD_00192 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IPHOHMKD_00194 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
IPHOHMKD_00195 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
IPHOHMKD_00196 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
IPHOHMKD_00197 2.17e-102 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPHOHMKD_00198 1.06e-281 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
IPHOHMKD_00199 1.21e-111 - - - - - - - -
IPHOHMKD_00200 4.81e-76 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
IPHOHMKD_00201 4.17e-67 - - - - - - - -
IPHOHMKD_00202 1.22e-125 - - - - - - - -
IPHOHMKD_00203 2.98e-90 - - - - - - - -
IPHOHMKD_00204 2.41e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
IPHOHMKD_00205 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
IPHOHMKD_00206 1.82e-126 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
IPHOHMKD_00207 7.42e-125 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
IPHOHMKD_00208 5.78e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IPHOHMKD_00209 1.78e-209 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IPHOHMKD_00210 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
IPHOHMKD_00211 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
IPHOHMKD_00212 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
IPHOHMKD_00213 2.21e-56 - - - - - - - -
IPHOHMKD_00214 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
IPHOHMKD_00215 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
IPHOHMKD_00216 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IPHOHMKD_00217 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
IPHOHMKD_00218 2.6e-185 - - - - - - - -
IPHOHMKD_00219 1.21e-94 tagD 2.7.7.15, 2.7.7.39 - IM ko:K00968,ko:K00980 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Glycerol-3-phosphate cytidylyltransferase
IPHOHMKD_00220 4.5e-303 tagB 2.7.8.12, 2.7.8.45 - M ko:K09809,ko:K21591 - ko00000,ko01000 glycerophosphotransferase
IPHOHMKD_00221 0.0 tagF2 2.7.8.12 - H ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IPHOHMKD_00222 9.52e-175 - - - S - - - Psort location CytoplasmicMembrane, score
IPHOHMKD_00223 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_00224 3.13e-99 - - - L - - - Transposase DDE domain
IPHOHMKD_00225 6.75e-17 - - - S - - - Psort location CytoplasmicMembrane, score
IPHOHMKD_00226 3.37e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IPHOHMKD_00227 1.11e-91 - - - - - - - -
IPHOHMKD_00229 9.12e-31 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
IPHOHMKD_00230 1.16e-29 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
IPHOHMKD_00231 8.9e-96 ywnA - - K - - - Transcriptional regulator
IPHOHMKD_00232 5.2e-156 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_00233 5.71e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IPHOHMKD_00234 1.15e-152 - - - - - - - -
IPHOHMKD_00235 2.92e-57 - - - - - - - -
IPHOHMKD_00236 1.55e-55 - - - - - - - -
IPHOHMKD_00237 0.0 ydiC - - EGP - - - Major Facilitator
IPHOHMKD_00238 8.98e-86 - - - K - - - helix_turn_helix, mercury resistance
IPHOHMKD_00239 4.25e-198 - - - L ko:K07482 - ko00000 Integrase core domain
IPHOHMKD_00240 0.0 hpk2 - - T - - - Histidine kinase
IPHOHMKD_00241 1.33e-165 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
IPHOHMKD_00242 2.42e-65 - - - - - - - -
IPHOHMKD_00243 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
IPHOHMKD_00244 6.86e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPHOHMKD_00245 3.35e-75 - - - - - - - -
IPHOHMKD_00246 2.87e-56 - - - - - - - -
IPHOHMKD_00247 1.76e-236 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
IPHOHMKD_00248 4.16e-108 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
IPHOHMKD_00249 1.78e-32 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
IPHOHMKD_00250 6.2e-134 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
IPHOHMKD_00251 1.49e-63 - - - - - - - -
IPHOHMKD_00252 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
IPHOHMKD_00253 1.17e-135 - - - K - - - transcriptional regulator
IPHOHMKD_00254 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
IPHOHMKD_00255 8.31e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
IPHOHMKD_00256 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
IPHOHMKD_00257 7.93e-290 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
IPHOHMKD_00258 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IPHOHMKD_00259 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
IPHOHMKD_00260 2.75e-156 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
IPHOHMKD_00261 7.98e-80 - - - M - - - Lysin motif
IPHOHMKD_00262 2.31e-95 - - - M - - - LysM domain protein
IPHOHMKD_00263 4.2e-88 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
IPHOHMKD_00264 4.29e-227 - - - - - - - -
IPHOHMKD_00265 2.8e-169 - - - - - - - -
IPHOHMKD_00266 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
IPHOHMKD_00267 1.96e-73 - - - - - - - -
IPHOHMKD_00268 9.17e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPHOHMKD_00269 1.08e-101 - - - S ko:K02348 - ko00000 GNAT family
IPHOHMKD_00270 1.24e-99 - - - K - - - Transcriptional regulator
IPHOHMKD_00271 9.59e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IPHOHMKD_00272 2.18e-53 - - - - - - - -
IPHOHMKD_00273 5.3e-265 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IPHOHMKD_00274 5.58e-181 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IPHOHMKD_00275 3.14e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IPHOHMKD_00276 5.09e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IPHOHMKD_00277 4.3e-124 - - - K - - - Cupin domain
IPHOHMKD_00278 8.08e-110 - - - S - - - ASCH
IPHOHMKD_00279 1.88e-111 - - - K - - - GNAT family
IPHOHMKD_00280 8.71e-117 - - - K - - - acetyltransferase
IPHOHMKD_00281 2.06e-30 - - - - - - - -
IPHOHMKD_00282 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
IPHOHMKD_00283 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IPHOHMKD_00284 1.08e-243 - - - - - - - -
IPHOHMKD_00285 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
IPHOHMKD_00286 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
IPHOHMKD_00288 7.89e-304 xylP1 - - G - - - MFS/sugar transport protein
IPHOHMKD_00289 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
IPHOHMKD_00290 2.97e-41 - - - - - - - -
IPHOHMKD_00291 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
IPHOHMKD_00292 6.4e-54 - - - - - - - -
IPHOHMKD_00293 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
IPHOHMKD_00294 4.28e-227 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IPHOHMKD_00295 1.45e-79 - - - S - - - CHY zinc finger
IPHOHMKD_00296 1.06e-143 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
IPHOHMKD_00297 1.13e-157 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IPHOHMKD_00298 4.45e-116 metP_2 - - U ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IPHOHMKD_00299 4.64e-186 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPHOHMKD_00300 3.43e-281 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IPHOHMKD_00301 1.57e-280 - - - - - - - -
IPHOHMKD_00302 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
IPHOHMKD_00303 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IPHOHMKD_00304 3.93e-59 - - - - - - - -
IPHOHMKD_00305 2.39e-121 - - - K - - - Transcriptional regulator PadR-like family
IPHOHMKD_00306 0.0 - - - P - - - Major Facilitator Superfamily
IPHOHMKD_00307 3.5e-307 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
IPHOHMKD_00308 9e-227 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
IPHOHMKD_00309 8.95e-60 - - - - - - - -
IPHOHMKD_00310 6.06e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
IPHOHMKD_00311 6.87e-153 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
IPHOHMKD_00312 0.0 sufI - - Q - - - Multicopper oxidase
IPHOHMKD_00313 5.34e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
IPHOHMKD_00314 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
IPHOHMKD_00315 1.61e-294 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
IPHOHMKD_00316 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
IPHOHMKD_00317 1.52e-103 - - - - - - - -
IPHOHMKD_00318 1.46e-100 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IPHOHMKD_00319 1.49e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
IPHOHMKD_00320 2.42e-207 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IPHOHMKD_00321 4.06e-102 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
IPHOHMKD_00322 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IPHOHMKD_00323 2.7e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_00324 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
IPHOHMKD_00325 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IPHOHMKD_00326 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
IPHOHMKD_00327 8.72e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IPHOHMKD_00328 0.0 - - - M - - - domain protein
IPHOHMKD_00329 8.01e-88 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
IPHOHMKD_00330 1.82e-34 - - - S - - - Immunity protein 74
IPHOHMKD_00331 8.54e-163 - - - - - - - -
IPHOHMKD_00332 2.95e-46 - - - - - - - -
IPHOHMKD_00333 7.74e-86 - - - - - - - -
IPHOHMKD_00334 4.05e-89 - - - S - - - Immunity protein 63
IPHOHMKD_00335 6.88e-32 - - - - - - - -
IPHOHMKD_00336 2.75e-51 - - - - - - - -
IPHOHMKD_00337 3.75e-153 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
IPHOHMKD_00338 1.58e-262 - - - EGP - - - Transporter, major facilitator family protein
IPHOHMKD_00339 7.67e-62 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IPHOHMKD_00340 4.24e-106 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IPHOHMKD_00341 4.75e-212 - - - K - - - Transcriptional regulator
IPHOHMKD_00342 8.38e-192 - - - S - - - hydrolase
IPHOHMKD_00343 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IPHOHMKD_00344 8.8e-265 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IPHOHMKD_00346 6.32e-149 - - - - - - - -
IPHOHMKD_00348 1.74e-90 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
IPHOHMKD_00349 6.87e-153 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
IPHOHMKD_00350 3.91e-145 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
IPHOHMKD_00351 7.78e-126 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
IPHOHMKD_00352 5.5e-42 - - - - - - - -
IPHOHMKD_00353 0.0 - - - L - - - DNA helicase
IPHOHMKD_00354 1.44e-181 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
IPHOHMKD_00355 8.19e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IPHOHMKD_00356 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
IPHOHMKD_00357 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPHOHMKD_00358 9.68e-34 - - - - - - - -
IPHOHMKD_00359 3.55e-99 - - - S - - - Domain of unknown function (DUF3284)
IPHOHMKD_00360 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPHOHMKD_00361 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IPHOHMKD_00362 4.21e-210 - - - GK - - - ROK family
IPHOHMKD_00363 1.14e-173 yecA - - K - - - Helix-turn-helix domain, rpiR family
IPHOHMKD_00364 1.7e-243 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPHOHMKD_00365 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
IPHOHMKD_00366 1.37e-290 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
IPHOHMKD_00367 1.89e-228 - - - - - - - -
IPHOHMKD_00368 2.14e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
IPHOHMKD_00369 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
IPHOHMKD_00370 5.43e-91 - - - F - - - DNA mismatch repair protein MutT
IPHOHMKD_00371 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPHOHMKD_00373 2.45e-267 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
IPHOHMKD_00374 8.73e-135 mutR - - K ko:K20373,ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
IPHOHMKD_00376 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
IPHOHMKD_00377 3.23e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IPHOHMKD_00378 7.17e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IPHOHMKD_00379 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
IPHOHMKD_00380 2.26e-209 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IPHOHMKD_00381 1.9e-230 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
IPHOHMKD_00382 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IPHOHMKD_00383 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
IPHOHMKD_00384 3.13e-99 - - - L - - - Transposase DDE domain
IPHOHMKD_00385 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_00386 2.95e-57 - - - S - - - ankyrin repeats
IPHOHMKD_00387 5.3e-49 - - - - - - - -
IPHOHMKD_00388 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
IPHOHMKD_00389 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IPHOHMKD_00390 2.22e-193 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
IPHOHMKD_00391 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IPHOHMKD_00392 5.45e-234 - - - S - - - DUF218 domain
IPHOHMKD_00393 8.69e-179 - - - - - - - -
IPHOHMKD_00394 1.45e-191 yxeH - - S - - - hydrolase
IPHOHMKD_00395 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
IPHOHMKD_00396 6.05e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
IPHOHMKD_00397 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
IPHOHMKD_00398 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IPHOHMKD_00399 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IPHOHMKD_00400 9.67e-311 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPHOHMKD_00401 2.28e-290 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
IPHOHMKD_00402 7.51e-159 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
IPHOHMKD_00403 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IPHOHMKD_00404 2.3e-170 - - - S - - - YheO-like PAS domain
IPHOHMKD_00405 2.41e-37 - - - - - - - -
IPHOHMKD_00406 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPHOHMKD_00407 6.26e-306 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IPHOHMKD_00408 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
IPHOHMKD_00409 1.49e-273 - - - J - - - translation release factor activity
IPHOHMKD_00410 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
IPHOHMKD_00411 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
IPHOHMKD_00412 5.58e-195 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
IPHOHMKD_00413 1.84e-189 - - - - - - - -
IPHOHMKD_00414 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IPHOHMKD_00415 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IPHOHMKD_00416 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IPHOHMKD_00417 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IPHOHMKD_00418 2.58e-85 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
IPHOHMKD_00419 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
IPHOHMKD_00420 5.58e-248 - - - P ko:K02051 - ko00000,ko00002,ko02000 ABC transporter, substratebinding protein
IPHOHMKD_00421 3.52e-201 - - - U ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IPHOHMKD_00422 2.02e-171 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
IPHOHMKD_00423 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
IPHOHMKD_00424 2.61e-260 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IPHOHMKD_00425 3.61e-244 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IPHOHMKD_00426 2.79e-293 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IPHOHMKD_00427 7.9e-165 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
IPHOHMKD_00428 2.47e-273 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
IPHOHMKD_00429 2.63e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IPHOHMKD_00430 1.3e-110 queT - - S - - - QueT transporter
IPHOHMKD_00431 4.87e-148 - - - S - - - (CBS) domain
IPHOHMKD_00432 0.0 - - - S - - - Putative peptidoglycan binding domain
IPHOHMKD_00433 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IPHOHMKD_00434 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IPHOHMKD_00435 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IPHOHMKD_00436 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
IPHOHMKD_00437 7.72e-57 yabO - - J - - - S4 domain protein
IPHOHMKD_00439 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
IPHOHMKD_00440 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
IPHOHMKD_00441 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IPHOHMKD_00442 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
IPHOHMKD_00443 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPHOHMKD_00444 7.52e-207 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IPHOHMKD_00445 8.83e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPHOHMKD_00446 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
IPHOHMKD_00449 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
IPHOHMKD_00452 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
IPHOHMKD_00453 1.75e-193 - - - S - - - Calcineurin-like phosphoesterase
IPHOHMKD_00456 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_00457 3.13e-99 - - - L - - - Transposase DDE domain
IPHOHMKD_00459 3.01e-64 - - - S - - - Cupin 2, conserved barrel domain protein
IPHOHMKD_00460 1.38e-71 - - - S - - - Cupin domain
IPHOHMKD_00461 3.62e-211 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
IPHOHMKD_00462 1.59e-247 ysdE - - P - - - Citrate transporter
IPHOHMKD_00463 1.06e-195 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
IPHOHMKD_00464 8.87e-174 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPHOHMKD_00465 2.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
IPHOHMKD_00466 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
IPHOHMKD_00467 5.44e-175 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IPHOHMKD_00468 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IPHOHMKD_00469 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IPHOHMKD_00470 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
IPHOHMKD_00471 7.36e-94 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
IPHOHMKD_00472 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
IPHOHMKD_00473 3.76e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
IPHOHMKD_00474 1.71e-302 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
IPHOHMKD_00475 3.83e-198 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IPHOHMKD_00477 1.43e-66 - - - L - - - Belongs to the 'phage' integrase family
IPHOHMKD_00482 2.34e-39 - - - K - - - Helix-turn-helix XRE-family like proteins
IPHOHMKD_00483 1.32e-19 - - - K - - - Helix-turn-helix
IPHOHMKD_00484 4.44e-125 - - - K - - - ORF6N domain
IPHOHMKD_00485 5.09e-10 - - - - - - - -
IPHOHMKD_00491 6.4e-53 - - - S - - - Siphovirus Gp157
IPHOHMKD_00492 1.74e-202 - - - S - - - helicase activity
IPHOHMKD_00493 4.31e-11 - - - S - - - HNH endonuclease
IPHOHMKD_00494 2.32e-92 - - - L - - - AAA domain
IPHOHMKD_00495 4.91e-28 - - - - - - - -
IPHOHMKD_00496 2.35e-97 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
IPHOHMKD_00497 1.97e-05 - - - S ko:K06919 - ko00000 Virulence-associated protein E
IPHOHMKD_00498 2.15e-145 - - - S ko:K06919 - ko00000 Virulence-associated protein E
IPHOHMKD_00499 1.32e-50 - - - S - - - VRR_NUC
IPHOHMKD_00500 8.62e-19 - - - - - - - -
IPHOHMKD_00501 1.48e-93 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 site-specific DNA-methyltransferase (adenine-specific) activity
IPHOHMKD_00503 1.82e-11 - - - - - - - -
IPHOHMKD_00505 9.52e-43 - - - - - - - -
IPHOHMKD_00510 3.86e-13 - - - - - - - -
IPHOHMKD_00511 1.06e-214 - - - S - - - Terminase
IPHOHMKD_00512 3.54e-128 - - - S - - - Phage portal protein
IPHOHMKD_00513 4.62e-70 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Clp protease
IPHOHMKD_00514 3.19e-141 - - - S - - - Phage capsid family
IPHOHMKD_00515 3.34e-23 - - - - - - - -
IPHOHMKD_00516 1.74e-31 - - - - - - - -
IPHOHMKD_00517 2.16e-43 - - - - - - - -
IPHOHMKD_00518 6.47e-29 - - - - - - - -
IPHOHMKD_00519 1.07e-43 - - - S - - - Phage tail tube protein
IPHOHMKD_00521 7.63e-194 - - - L - - - Phage tail tape measure protein TP901
IPHOHMKD_00523 1.86e-166 - - - LM - - - DNA recombination
IPHOHMKD_00524 5.09e-92 - - - S - - - Protein of unknown function (DUF1617)
IPHOHMKD_00526 8.36e-53 - - - - - - - -
IPHOHMKD_00528 3.56e-07 - - - S - - - Bacteriophage A118-like holin, Hol118
IPHOHMKD_00529 2.62e-98 - - - M - - - Glycosyl hydrolases family 25
IPHOHMKD_00530 1.31e-196 - - - G - - - Peptidase_C39 like family
IPHOHMKD_00531 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
IPHOHMKD_00532 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
IPHOHMKD_00533 4.22e-216 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
IPHOHMKD_00534 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
IPHOHMKD_00535 0.0 levR - - K - - - Sigma-54 interaction domain
IPHOHMKD_00536 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
IPHOHMKD_00537 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
IPHOHMKD_00538 3.15e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPHOHMKD_00539 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
IPHOHMKD_00540 1.7e-315 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
IPHOHMKD_00541 3.01e-183 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IPHOHMKD_00542 3.37e-175 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
IPHOHMKD_00543 1.32e-233 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
IPHOHMKD_00544 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
IPHOHMKD_00545 6.04e-227 - - - EG - - - EamA-like transporter family
IPHOHMKD_00546 1.11e-164 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IPHOHMKD_00547 1.26e-144 zmp2 - - O - - - Zinc-dependent metalloprotease
IPHOHMKD_00548 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
IPHOHMKD_00549 3.27e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IPHOHMKD_00550 8.47e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
IPHOHMKD_00551 9.43e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
IPHOHMKD_00552 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IPHOHMKD_00553 4.91e-265 yacL - - S - - - domain protein
IPHOHMKD_00554 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IPHOHMKD_00555 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IPHOHMKD_00556 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IPHOHMKD_00557 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPHOHMKD_00558 1.75e-126 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
IPHOHMKD_00559 4.58e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
IPHOHMKD_00560 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IPHOHMKD_00561 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IPHOHMKD_00562 1.09e-127 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IPHOHMKD_00563 2.81e-202 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
IPHOHMKD_00564 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IPHOHMKD_00565 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IPHOHMKD_00566 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IPHOHMKD_00567 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IPHOHMKD_00568 1.01e-226 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
IPHOHMKD_00569 4.82e-86 - - - L - - - nuclease
IPHOHMKD_00570 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IPHOHMKD_00571 2.37e-140 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
IPHOHMKD_00572 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPHOHMKD_00573 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPHOHMKD_00574 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
IPHOHMKD_00575 1.11e-139 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
IPHOHMKD_00576 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IPHOHMKD_00577 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPHOHMKD_00578 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IPHOHMKD_00579 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IPHOHMKD_00580 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
IPHOHMKD_00581 1.82e-152 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IPHOHMKD_00582 2.11e-66 yaaQ - - S - - - Cyclic-di-AMP receptor
IPHOHMKD_00583 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IPHOHMKD_00584 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
IPHOHMKD_00585 2.64e-213 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IPHOHMKD_00586 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
IPHOHMKD_00587 4.95e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IPHOHMKD_00588 9.25e-271 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
IPHOHMKD_00589 8.04e-187 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
IPHOHMKD_00590 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IPHOHMKD_00591 6.51e-178 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
IPHOHMKD_00592 3.8e-176 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IPHOHMKD_00593 3.46e-242 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
IPHOHMKD_00594 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
IPHOHMKD_00595 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
IPHOHMKD_00596 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IPHOHMKD_00597 3.62e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IPHOHMKD_00598 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
IPHOHMKD_00599 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IPHOHMKD_00600 2.38e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
IPHOHMKD_00601 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPHOHMKD_00602 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IPHOHMKD_00603 0.0 ydaO - - E - - - amino acid
IPHOHMKD_00604 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
IPHOHMKD_00605 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
IPHOHMKD_00606 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
IPHOHMKD_00607 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
IPHOHMKD_00608 2.94e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
IPHOHMKD_00609 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IPHOHMKD_00610 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IPHOHMKD_00611 1.69e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IPHOHMKD_00612 2.59e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
IPHOHMKD_00613 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
IPHOHMKD_00614 8.9e-317 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IPHOHMKD_00615 4.66e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
IPHOHMKD_00616 2.22e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
IPHOHMKD_00617 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
IPHOHMKD_00618 8.04e-189 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IPHOHMKD_00619 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IPHOHMKD_00620 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
IPHOHMKD_00621 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
IPHOHMKD_00622 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
IPHOHMKD_00623 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IPHOHMKD_00624 1.04e-211 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IPHOHMKD_00625 6.63e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
IPHOHMKD_00626 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IPHOHMKD_00627 3.69e-159 - - - T - - - Putative diguanylate phosphodiesterase
IPHOHMKD_00628 0.0 nox - - C - - - NADH oxidase
IPHOHMKD_00629 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IPHOHMKD_00630 5.03e-140 yviA - - S - - - Protein of unknown function (DUF421)
IPHOHMKD_00631 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
IPHOHMKD_00632 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IPHOHMKD_00633 3.86e-256 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IPHOHMKD_00634 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
IPHOHMKD_00635 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IPHOHMKD_00636 1.89e-134 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IPHOHMKD_00637 5.33e-268 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
IPHOHMKD_00638 3.85e-151 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
IPHOHMKD_00639 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IPHOHMKD_00640 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IPHOHMKD_00641 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IPHOHMKD_00642 1.07e-301 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
IPHOHMKD_00643 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
IPHOHMKD_00644 8.62e-114 - - - S - - - Short repeat of unknown function (DUF308)
IPHOHMKD_00645 2e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
IPHOHMKD_00646 6.21e-241 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
IPHOHMKD_00647 1.21e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
IPHOHMKD_00648 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
IPHOHMKD_00649 3.64e-224 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPHOHMKD_00650 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IPHOHMKD_00652 9.37e-311 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
IPHOHMKD_00653 9.53e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
IPHOHMKD_00654 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IPHOHMKD_00655 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
IPHOHMKD_00656 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IPHOHMKD_00657 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IPHOHMKD_00658 2.42e-169 - - - - - - - -
IPHOHMKD_00659 0.0 eriC - - P ko:K03281 - ko00000 chloride
IPHOHMKD_00660 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
IPHOHMKD_00661 6.35e-178 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
IPHOHMKD_00662 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IPHOHMKD_00663 9.78e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IPHOHMKD_00664 1.14e-20 - - - M - - - Domain of unknown function (DUF5011)
IPHOHMKD_00665 0.0 - - - M - - - Domain of unknown function (DUF5011)
IPHOHMKD_00666 0.0 - - - M - - - Domain of unknown function (DUF5011)
IPHOHMKD_00667 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IPHOHMKD_00668 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_00669 7.98e-137 - - - - - - - -
IPHOHMKD_00670 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
IPHOHMKD_00671 5.71e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IPHOHMKD_00672 5e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
IPHOHMKD_00673 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
IPHOHMKD_00674 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
IPHOHMKD_00675 2.41e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IPHOHMKD_00676 1.03e-197 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
IPHOHMKD_00677 1.03e-211 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
IPHOHMKD_00678 2.54e-213 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
IPHOHMKD_00679 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
IPHOHMKD_00680 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IPHOHMKD_00681 5.68e-156 - - - S - - - Protein of unknown function (DUF1361)
IPHOHMKD_00682 9.72e-191 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IPHOHMKD_00683 2.18e-182 ybbR - - S - - - YbbR-like protein
IPHOHMKD_00684 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPHOHMKD_00685 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IPHOHMKD_00686 5.44e-159 - - - T - - - EAL domain
IPHOHMKD_00687 5.43e-188 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
IPHOHMKD_00688 4.93e-135 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_00689 1.8e-234 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
IPHOHMKD_00690 2.18e-245 - - - L - - - Transposase and inactivated derivatives, IS30 family
IPHOHMKD_00691 3.38e-70 - - - - - - - -
IPHOHMKD_00692 2.49e-95 - - - - - - - -
IPHOHMKD_00693 2.87e-168 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
IPHOHMKD_00694 4.86e-193 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
IPHOHMKD_00695 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IPHOHMKD_00696 2.6e-185 - - - - - - - -
IPHOHMKD_00698 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
IPHOHMKD_00699 3.88e-46 - - - - - - - -
IPHOHMKD_00700 1.71e-116 - - - V - - - VanZ like family
IPHOHMKD_00701 6.14e-314 - - - EGP - - - Major Facilitator
IPHOHMKD_00702 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
IPHOHMKD_00703 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IPHOHMKD_00704 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
IPHOHMKD_00705 2.72e-196 licD - - M ko:K07271 - ko00000,ko01000 LicD family
IPHOHMKD_00706 6.16e-107 - - - K - - - Transcriptional regulator
IPHOHMKD_00707 1.36e-27 - - - - - - - -
IPHOHMKD_00708 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
IPHOHMKD_00709 2.18e-245 - - - L - - - Transposase and inactivated derivatives, IS30 family
IPHOHMKD_00710 2.72e-225 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IPHOHMKD_00711 6.56e-188 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IPHOHMKD_00712 1.06e-195 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
IPHOHMKD_00713 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IPHOHMKD_00714 6.37e-232 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
IPHOHMKD_00715 7.12e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IPHOHMKD_00716 0.0 oatA - - I - - - Acyltransferase
IPHOHMKD_00717 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IPHOHMKD_00718 1.89e-90 - - - O - - - OsmC-like protein
IPHOHMKD_00719 4.45e-60 - - - - - - - -
IPHOHMKD_00720 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
IPHOHMKD_00721 2.49e-114 - - - - - - - -
IPHOHMKD_00722 1.23e-189 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
IPHOHMKD_00723 7.48e-96 - - - F - - - Nudix hydrolase
IPHOHMKD_00724 1.48e-27 - - - - - - - -
IPHOHMKD_00725 2.45e-134 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
IPHOHMKD_00726 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
IPHOHMKD_00727 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
IPHOHMKD_00728 1.01e-188 - - - - - - - -
IPHOHMKD_00729 6.94e-146 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
IPHOHMKD_00730 7.9e-269 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IPHOHMKD_00731 1.03e-217 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPHOHMKD_00732 2.12e-53 - - - - - - - -
IPHOHMKD_00734 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_00735 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IPHOHMKD_00736 3.14e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IPHOHMKD_00737 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IPHOHMKD_00738 2.1e-109 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IPHOHMKD_00739 7.77e-197 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
IPHOHMKD_00740 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
IPHOHMKD_00741 3.16e-182 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
IPHOHMKD_00742 1.77e-93 steT - - E ko:K03294 - ko00000 amino acid
IPHOHMKD_00743 8.35e-85 steT - - E ko:K03294 - ko00000 amino acid
IPHOHMKD_00744 7.87e-75 steT - - E ko:K03294 - ko00000 amino acid
IPHOHMKD_00745 1.26e-95 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IPHOHMKD_00746 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
IPHOHMKD_00747 8.83e-93 - - - K - - - MarR family
IPHOHMKD_00748 3.22e-269 - - - EGP - - - Major Facilitator Superfamily
IPHOHMKD_00749 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
IPHOHMKD_00750 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_00751 5.95e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IPHOHMKD_00752 4.6e-102 rppH3 - - F - - - NUDIX domain
IPHOHMKD_00753 1.95e-61 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
IPHOHMKD_00754 1.61e-36 - - - - - - - -
IPHOHMKD_00755 1.35e-165 pgm3 - - G - - - Phosphoglycerate mutase family
IPHOHMKD_00756 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
IPHOHMKD_00757 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
IPHOHMKD_00758 4.16e-227 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IPHOHMKD_00759 1.11e-143 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
IPHOHMKD_00760 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IPHOHMKD_00761 2.08e-211 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
IPHOHMKD_00762 1.22e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
IPHOHMKD_00763 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
IPHOHMKD_00765 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
IPHOHMKD_00766 7.9e-49 yeeA - - V - - - Type II restriction enzyme, methylase subunits
IPHOHMKD_00767 0.0 - - - L - - - DEAD-like helicases superfamily
IPHOHMKD_00768 3.66e-162 yeeC - - P - - - T5orf172
IPHOHMKD_00771 1.03e-81 - - - L - - - AAA domain
IPHOHMKD_00772 6.18e-130 - - - K - - - Transcriptional regulator, AbiEi antitoxin
IPHOHMKD_00773 9.75e-176 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
IPHOHMKD_00774 3.51e-37 - - - K - - - Helix-turn-helix XRE-family like proteins
IPHOHMKD_00775 1.04e-69 - - - - - - - -
IPHOHMKD_00776 7.32e-79 - - - K - - - Helix-turn-helix domain
IPHOHMKD_00777 1.57e-140 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
IPHOHMKD_00778 1.22e-242 - - - S - - - Cysteine-rich secretory protein family
IPHOHMKD_00779 1.59e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
IPHOHMKD_00780 1.89e-118 - - - D - - - nuclear chromosome segregation
IPHOHMKD_00781 6.46e-111 - - - - - - - -
IPHOHMKD_00782 5.53e-205 - - - S - - - Domain of unknown function (DUF4767)
IPHOHMKD_00783 6.35e-69 - - - - - - - -
IPHOHMKD_00784 3.61e-61 - - - S - - - MORN repeat
IPHOHMKD_00785 0.0 XK27_09800 - - I - - - Acyltransferase family
IPHOHMKD_00786 1.81e-50 ydaS - - S - - - Transglycosylase associated protein
IPHOHMKD_00787 5.59e-116 - - - - - - - -
IPHOHMKD_00788 5.74e-32 - - - - - - - -
IPHOHMKD_00789 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
IPHOHMKD_00790 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
IPHOHMKD_00791 1.31e-188 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
IPHOHMKD_00792 2.57e-212 yjdB - - S - - - Domain of unknown function (DUF4767)
IPHOHMKD_00793 5.21e-62 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
IPHOHMKD_00794 8.07e-182 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
IPHOHMKD_00795 1.52e-84 - - - S - - - Putative inner membrane protein (DUF1819)
IPHOHMKD_00796 1.15e-93 - - - S - - - Domain of unknown function (DUF1788)
IPHOHMKD_00797 0.0 - - - K - - - RNA-binding protein homologous to eukaryotic snRNP
IPHOHMKD_00798 0.0 - - - LV - - - Eco57I restriction-modification methylase
IPHOHMKD_00799 2.15e-189 - - - L - - - Belongs to the 'phage' integrase family
IPHOHMKD_00800 6.27e-202 - - - V - - - Type II restriction enzyme, methylase subunits
IPHOHMKD_00801 2.34e-280 - - - S - - - PglZ domain
IPHOHMKD_00802 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
IPHOHMKD_00803 0.000211 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
IPHOHMKD_00804 5.97e-61 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
IPHOHMKD_00805 1.44e-33 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
IPHOHMKD_00806 1.23e-108 - - - L - - - PFAM Integrase catalytic region
IPHOHMKD_00808 1.39e-118 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
IPHOHMKD_00809 0.0 - - - M - - - MucBP domain
IPHOHMKD_00810 1.42e-08 - - - - - - - -
IPHOHMKD_00811 1.27e-115 - - - S - - - AAA domain
IPHOHMKD_00812 1.3e-167 - - - K - - - sequence-specific DNA binding
IPHOHMKD_00813 1.05e-121 - - - K - - - Helix-turn-helix domain
IPHOHMKD_00814 6.52e-219 - - - K - - - Transcriptional regulator
IPHOHMKD_00815 0.0 - - - C - - - FMN_bind
IPHOHMKD_00817 4.13e-104 - - - K - - - Transcriptional regulator
IPHOHMKD_00818 4.71e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPHOHMKD_00819 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
IPHOHMKD_00820 3.13e-99 - - - L - - - Transposase DDE domain
IPHOHMKD_00821 2.74e-88 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_00822 5.62e-254 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
IPHOHMKD_00823 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
IPHOHMKD_00824 1.32e-290 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IPHOHMKD_00825 9.05e-55 - - - - - - - -
IPHOHMKD_00826 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
IPHOHMKD_00827 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
IPHOHMKD_00828 9.95e-211 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IPHOHMKD_00829 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IPHOHMKD_00830 2.91e-179 - - - S - - - NADPH-dependent FMN reductase
IPHOHMKD_00831 1.86e-242 - - - - - - - -
IPHOHMKD_00832 1.89e-277 yibE - - S - - - overlaps another CDS with the same product name
IPHOHMKD_00833 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
IPHOHMKD_00834 4.97e-132 - - - K - - - FR47-like protein
IPHOHMKD_00835 2.5e-155 gpm5 - - G - - - Phosphoglycerate mutase family
IPHOHMKD_00836 3.33e-64 - - - - - - - -
IPHOHMKD_00837 4.24e-246 - - - I - - - alpha/beta hydrolase fold
IPHOHMKD_00838 0.0 xylP2 - - G - - - symporter
IPHOHMKD_00839 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IPHOHMKD_00840 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
IPHOHMKD_00841 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IPHOHMKD_00842 3.43e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
IPHOHMKD_00843 2.03e-155 azlC - - E - - - branched-chain amino acid
IPHOHMKD_00844 1.75e-47 - - - K - - - MerR HTH family regulatory protein
IPHOHMKD_00845 8.48e-154 - - - - - - - -
IPHOHMKD_00846 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
IPHOHMKD_00847 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
IPHOHMKD_00848 7.79e-112 - - - K - - - MerR HTH family regulatory protein
IPHOHMKD_00849 1.12e-76 - - - - - - - -
IPHOHMKD_00850 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
IPHOHMKD_00851 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
IPHOHMKD_00852 4.6e-169 - - - S - - - Putative threonine/serine exporter
IPHOHMKD_00853 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
IPHOHMKD_00854 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
IPHOHMKD_00855 4.15e-153 - - - I - - - phosphatase
IPHOHMKD_00856 3.88e-198 - - - I - - - alpha/beta hydrolase fold
IPHOHMKD_00857 3.03e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IPHOHMKD_00858 1.7e-118 - - - K - - - Transcriptional regulator
IPHOHMKD_00859 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
IPHOHMKD_00860 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
IPHOHMKD_00861 5.27e-153 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
IPHOHMKD_00862 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
IPHOHMKD_00863 1.62e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPHOHMKD_00871 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
IPHOHMKD_00872 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IPHOHMKD_00873 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_00874 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPHOHMKD_00875 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPHOHMKD_00876 8.58e-149 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
IPHOHMKD_00877 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IPHOHMKD_00878 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IPHOHMKD_00879 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IPHOHMKD_00880 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
IPHOHMKD_00881 6.16e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IPHOHMKD_00882 9.83e-141 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
IPHOHMKD_00883 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IPHOHMKD_00884 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IPHOHMKD_00885 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IPHOHMKD_00886 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IPHOHMKD_00887 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IPHOHMKD_00888 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IPHOHMKD_00889 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
IPHOHMKD_00890 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IPHOHMKD_00891 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IPHOHMKD_00892 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IPHOHMKD_00893 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IPHOHMKD_00894 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IPHOHMKD_00895 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IPHOHMKD_00896 1.75e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IPHOHMKD_00897 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IPHOHMKD_00898 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
IPHOHMKD_00899 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
IPHOHMKD_00900 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IPHOHMKD_00901 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IPHOHMKD_00902 1.19e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IPHOHMKD_00903 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IPHOHMKD_00904 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IPHOHMKD_00905 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPHOHMKD_00906 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
IPHOHMKD_00907 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IPHOHMKD_00908 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
IPHOHMKD_00909 3.78e-112 - - - S - - - NusG domain II
IPHOHMKD_00910 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IPHOHMKD_00911 3.19e-194 - - - S - - - FMN_bind
IPHOHMKD_00912 2.96e-285 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IPHOHMKD_00913 1.98e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPHOHMKD_00914 2.01e-211 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPHOHMKD_00915 2.49e-186 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPHOHMKD_00916 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IPHOHMKD_00917 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IPHOHMKD_00918 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
IPHOHMKD_00919 9.94e-209 yitS - - S - - - Uncharacterised protein, DegV family COG1307
IPHOHMKD_00920 1.03e-233 - - - S - - - Membrane
IPHOHMKD_00921 1.35e-261 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
IPHOHMKD_00922 4.41e-59 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
IPHOHMKD_00923 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IPHOHMKD_00924 1.36e-210 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPHOHMKD_00925 1.1e-233 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
IPHOHMKD_00926 5.43e-255 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IPHOHMKD_00927 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
IPHOHMKD_00928 1.24e-68 yitW - - S - - - Iron-sulfur cluster assembly protein
IPHOHMKD_00929 1.41e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
IPHOHMKD_00930 4.28e-225 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
IPHOHMKD_00931 7.7e-255 - - - K - - - Helix-turn-helix domain
IPHOHMKD_00932 4.49e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IPHOHMKD_00933 8.31e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IPHOHMKD_00934 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
IPHOHMKD_00935 2.11e-222 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IPHOHMKD_00936 3.86e-256 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IPHOHMKD_00937 1.18e-66 - - - - - - - -
IPHOHMKD_00938 1.31e-214 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IPHOHMKD_00939 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
IPHOHMKD_00940 8.69e-230 citR - - K - - - sugar-binding domain protein
IPHOHMKD_00941 3.88e-264 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
IPHOHMKD_00942 5.31e-242 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IPHOHMKD_00943 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
IPHOHMKD_00944 9.11e-208 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
IPHOHMKD_00945 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
IPHOHMKD_00946 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IPHOHMKD_00947 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
IPHOHMKD_00948 6.64e-121 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IPHOHMKD_00949 4.54e-207 mleR2 - - K - - - LysR family transcriptional regulator
IPHOHMKD_00950 6.5e-215 mleR - - K - - - LysR family
IPHOHMKD_00951 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
IPHOHMKD_00952 2.6e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
IPHOHMKD_00953 0.0 - - - E ko:K03294 - ko00000 Amino Acid
IPHOHMKD_00954 7.25e-127 - - - S - - - ECF transporter, substrate-specific component
IPHOHMKD_00955 6.07e-33 - - - - - - - -
IPHOHMKD_00956 0.0 - - - S ko:K06889 - ko00000 Alpha beta
IPHOHMKD_00957 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
IPHOHMKD_00958 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
IPHOHMKD_00959 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IPHOHMKD_00960 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IPHOHMKD_00961 1.89e-208 - - - S - - - L,D-transpeptidase catalytic domain
IPHOHMKD_00962 2.11e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IPHOHMKD_00963 8.5e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
IPHOHMKD_00964 3.86e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
IPHOHMKD_00965 3.41e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
IPHOHMKD_00966 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IPHOHMKD_00967 7.15e-110 yebE - - S - - - UPF0316 protein
IPHOHMKD_00968 1.63e-278 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IPHOHMKD_00969 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
IPHOHMKD_00970 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPHOHMKD_00971 9.48e-263 camS - - S - - - sex pheromone
IPHOHMKD_00972 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPHOHMKD_00973 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IPHOHMKD_00974 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPHOHMKD_00975 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
IPHOHMKD_00976 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPHOHMKD_00977 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_00978 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
IPHOHMKD_00979 7.89e-304 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPHOHMKD_00980 2.75e-213 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
IPHOHMKD_00981 5.63e-196 gntR - - K - - - rpiR family
IPHOHMKD_00982 1.34e-186 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
IPHOHMKD_00983 0.0 - - - L ko:K07487 - ko00000 Transposase
IPHOHMKD_00984 4.41e-59 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
IPHOHMKD_00985 4.25e-82 - - - S - - - Domain of unknown function (DUF4828)
IPHOHMKD_00986 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
IPHOHMKD_00987 3.21e-244 mocA - - S - - - Oxidoreductase
IPHOHMKD_00988 2.34e-315 yfmL - - L - - - DEAD DEAH box helicase
IPHOHMKD_00990 5.25e-99 int3 - - L - - - Belongs to the 'phage' integrase family
IPHOHMKD_00996 4.09e-38 - - - E - - - Zn peptidase
IPHOHMKD_00997 5.03e-32 - - - K - - - Helix-turn-helix XRE-family like proteins
IPHOHMKD_00999 5.6e-119 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
IPHOHMKD_01001 3.2e-85 - - - S - - - DNA binding
IPHOHMKD_01007 1.64e-32 - - - S - - - Putative HNHc nuclease
IPHOHMKD_01008 1.32e-48 - - - S - - - Putative HNHc nuclease
IPHOHMKD_01010 1.89e-94 - - - L - - - DnaD domain protein
IPHOHMKD_01011 1.24e-188 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
IPHOHMKD_01013 1.88e-62 - - - - - - - -
IPHOHMKD_01015 4.14e-20 - - - - - - - -
IPHOHMKD_01017 8.93e-35 - - - S - - - YopX protein
IPHOHMKD_01018 4.6e-49 - - - - - - - -
IPHOHMKD_01021 1.68e-13 - - - S - - - YopX protein
IPHOHMKD_01022 2.52e-37 - - - - - - - -
IPHOHMKD_01024 5.2e-98 - - - S - - - Transcriptional regulator, RinA family
IPHOHMKD_01026 4.28e-16 - - - V - - - HNH nucleases
IPHOHMKD_01027 6.69e-116 - - - L - - - HNH nucleases
IPHOHMKD_01029 5.72e-104 - - - L - - - Phage terminase, small subunit
IPHOHMKD_01030 0.0 - - - S - - - Phage Terminase
IPHOHMKD_01031 1.35e-34 - - - S - - - Protein of unknown function (DUF1056)
IPHOHMKD_01032 4.7e-282 - - - S - - - Phage portal protein
IPHOHMKD_01033 4.92e-163 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
IPHOHMKD_01034 6.63e-263 - - - S - - - peptidase activity
IPHOHMKD_01035 1.67e-68 - - - S - - - Phage gp6-like head-tail connector protein
IPHOHMKD_01036 1.21e-32 - - - S - - - Phage head-tail joining protein
IPHOHMKD_01037 3.79e-50 - - - - - - - -
IPHOHMKD_01039 2.32e-87 - - - S - - - Phage tail tube protein
IPHOHMKD_01041 5.58e-06 - - - - - - - -
IPHOHMKD_01042 0.0 - - - S - - - peptidoglycan catabolic process
IPHOHMKD_01043 1.47e-287 - - - S - - - Phage tail protein
IPHOHMKD_01044 0.0 - - - S - - - Phage minor structural protein
IPHOHMKD_01048 3.13e-67 - - - - - - - -
IPHOHMKD_01049 2.05e-212 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
IPHOHMKD_01050 1.52e-48 - - - S - - - Haemolysin XhlA
IPHOHMKD_01051 2.33e-54 - - - S - - - Bacteriophage holin
IPHOHMKD_01053 3.93e-99 - - - T - - - Universal stress protein family
IPHOHMKD_01054 6.8e-308 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPHOHMKD_01055 2.75e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
IPHOHMKD_01057 2.18e-96 - - - - - - - -
IPHOHMKD_01058 7.98e-137 - - - - - - - -
IPHOHMKD_01059 2.22e-169 - - - L - - - Helix-turn-helix domain
IPHOHMKD_01060 1.58e-204 - - - L ko:K07497 - ko00000 hmm pf00665
IPHOHMKD_01061 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IPHOHMKD_01062 5.77e-269 pbpX - - V - - - Beta-lactamase
IPHOHMKD_01063 3.43e-260 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IPHOHMKD_01064 8.66e-204 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
IPHOHMKD_01065 1.14e-168 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IPHOHMKD_01066 3.81e-47 - - - M - - - biosynthesis protein
IPHOHMKD_01067 2.07e-15 - 2.7.10.1 - D ko:K08252 - ko00000,ko01000 biosynthesis protein
IPHOHMKD_01068 1.18e-97 - 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyltransferase 26 family
IPHOHMKD_01069 1.56e-106 - - - M - - - Glycosyltransferase Family 4
IPHOHMKD_01070 5.36e-72 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IPHOHMKD_01071 1.15e-14 - - - M - - - -O-antigen
IPHOHMKD_01072 3.13e-99 - - - L - - - Transposase DDE domain
IPHOHMKD_01073 3.9e-88 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_01074 2.76e-30 - - - M - - - -O-antigen
IPHOHMKD_01075 3.45e-103 cps2J - - S - - - Polysaccharide biosynthesis protein
IPHOHMKD_01076 8.27e-85 - - - S - - - SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
IPHOHMKD_01077 2.86e-45 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IPHOHMKD_01078 3.08e-151 - - - - - - - -
IPHOHMKD_01079 1.86e-86 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_01080 1.31e-86 - - - L - - - Transposase DDE domain
IPHOHMKD_01081 7.71e-255 cps3I - - G - - - Acyltransferase family
IPHOHMKD_01082 9.83e-189 cps3J - - M - - - Domain of unknown function (DUF4422)
IPHOHMKD_01083 2.09e-305 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
IPHOHMKD_01084 5.73e-122 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
IPHOHMKD_01085 9.02e-70 - - - - - - - -
IPHOHMKD_01086 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
IPHOHMKD_01087 1.95e-41 - - - - - - - -
IPHOHMKD_01088 8.39e-38 - - - - - - - -
IPHOHMKD_01089 1.68e-131 - - - K - - - DNA-templated transcription, initiation
IPHOHMKD_01090 4.48e-167 - - - - - - - -
IPHOHMKD_01091 8.27e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
IPHOHMKD_01092 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
IPHOHMKD_01093 4.09e-172 lytE - - M - - - NlpC/P60 family
IPHOHMKD_01094 3.97e-64 - - - K - - - sequence-specific DNA binding
IPHOHMKD_01095 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
IPHOHMKD_01096 7.3e-216 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
IPHOHMKD_01097 1.13e-257 yueF - - S - - - AI-2E family transporter
IPHOHMKD_01098 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
IPHOHMKD_01099 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
IPHOHMKD_01100 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
IPHOHMKD_01101 1e-217 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
IPHOHMKD_01102 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
IPHOHMKD_01103 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IPHOHMKD_01104 0.0 - - - - - - - -
IPHOHMKD_01105 1.49e-252 - - - M - - - MucBP domain
IPHOHMKD_01106 3.19e-207 lysR5 - - K - - - LysR substrate binding domain
IPHOHMKD_01107 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
IPHOHMKD_01108 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
IPHOHMKD_01109 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
IPHOHMKD_01110 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPHOHMKD_01111 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPHOHMKD_01112 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IPHOHMKD_01113 1.62e-230 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IPHOHMKD_01114 3.4e-85 - - - K - - - Winged helix DNA-binding domain
IPHOHMKD_01115 8.38e-131 - - - L - - - Integrase
IPHOHMKD_01116 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
IPHOHMKD_01117 5.6e-41 - - - - - - - -
IPHOHMKD_01118 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
IPHOHMKD_01119 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPHOHMKD_01120 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
IPHOHMKD_01121 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
IPHOHMKD_01122 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IPHOHMKD_01123 1.88e-291 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IPHOHMKD_01124 3.5e-292 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IPHOHMKD_01125 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
IPHOHMKD_01126 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IPHOHMKD_01129 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
IPHOHMKD_01141 5.4e-118 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
IPHOHMKD_01142 2.22e-237 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
IPHOHMKD_01143 5.09e-124 - - - - - - - -
IPHOHMKD_01144 1.58e-122 - - - K - - - Acetyltransferase (GNAT) domain
IPHOHMKD_01145 1.7e-199 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
IPHOHMKD_01147 2.29e-293 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IPHOHMKD_01148 2.53e-240 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
IPHOHMKD_01149 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IPHOHMKD_01150 2.36e-217 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
IPHOHMKD_01151 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IPHOHMKD_01152 3.35e-157 - - - - - - - -
IPHOHMKD_01153 3.24e-272 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IPHOHMKD_01154 0.0 mdr - - EGP - - - Major Facilitator
IPHOHMKD_01155 2.58e-304 - - - N - - - Cell shape-determining protein MreB
IPHOHMKD_01156 0.0 - - - S - - - Pfam Methyltransferase
IPHOHMKD_01157 3.13e-99 - - - L - - - Transposase DDE domain
IPHOHMKD_01158 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_01159 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IPHOHMKD_01160 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IPHOHMKD_01161 9.32e-40 - - - - - - - -
IPHOHMKD_01162 3.54e-121 mraW1 - - J - - - Putative rRNA methylase
IPHOHMKD_01163 1.2e-159 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
IPHOHMKD_01164 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
IPHOHMKD_01165 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
IPHOHMKD_01166 8.35e-175 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IPHOHMKD_01167 5.24e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IPHOHMKD_01168 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
IPHOHMKD_01169 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
IPHOHMKD_01170 1.02e-258 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
IPHOHMKD_01171 1.87e-220 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IPHOHMKD_01172 3.05e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IPHOHMKD_01173 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IPHOHMKD_01174 7.43e-160 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IPHOHMKD_01175 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
IPHOHMKD_01176 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IPHOHMKD_01177 1.1e-312 XK27_06930 - - V ko:K01421 - ko00000 domain protein
IPHOHMKD_01179 3.63e-164 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
IPHOHMKD_01180 3.06e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IPHOHMKD_01181 1.49e-225 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
IPHOHMKD_01182 6.96e-198 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPHOHMKD_01183 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
IPHOHMKD_01184 1.64e-151 - - - GM - - - NAD(P)H-binding
IPHOHMKD_01185 2.68e-204 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IPHOHMKD_01186 1.97e-191 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
IPHOHMKD_01187 7.83e-140 - - - - - - - -
IPHOHMKD_01188 7.25e-284 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IPHOHMKD_01189 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
IPHOHMKD_01190 3.11e-73 - - - - - - - -
IPHOHMKD_01191 4.56e-78 - - - - - - - -
IPHOHMKD_01192 1.06e-146 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
IPHOHMKD_01193 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
IPHOHMKD_01194 8.47e-117 - - - - - - - -
IPHOHMKD_01195 7.12e-62 - - - - - - - -
IPHOHMKD_01196 0.0 uvrA2 - - L - - - ABC transporter
IPHOHMKD_01199 4.29e-87 - - - - - - - -
IPHOHMKD_01200 9.03e-16 - - - - - - - -
IPHOHMKD_01201 3.89e-237 - - - - - - - -
IPHOHMKD_01202 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
IPHOHMKD_01203 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
IPHOHMKD_01204 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IPHOHMKD_01205 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IPHOHMKD_01206 0.0 - - - S - - - Protein conserved in bacteria
IPHOHMKD_01207 5.16e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
IPHOHMKD_01208 9.14e-146 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
IPHOHMKD_01209 2.31e-232 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
IPHOHMKD_01210 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
IPHOHMKD_01211 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
IPHOHMKD_01212 2.69e-316 dinF - - V - - - MatE
IPHOHMKD_01213 1.79e-42 - - - - - - - -
IPHOHMKD_01216 1.21e-103 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
IPHOHMKD_01217 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
IPHOHMKD_01218 5.64e-107 - - - - - - - -
IPHOHMKD_01219 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
IPHOHMKD_01220 6.25e-138 - - - - - - - -
IPHOHMKD_01221 0.0 celR - - K - - - PRD domain
IPHOHMKD_01222 1.34e-104 - - - S - - - Domain of unknown function (DUF3284)
IPHOHMKD_01223 2.37e-68 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
IPHOHMKD_01224 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
IPHOHMKD_01225 1.02e-285 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPHOHMKD_01226 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IPHOHMKD_01227 7.06e-271 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
IPHOHMKD_01228 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
IPHOHMKD_01229 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPHOHMKD_01230 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
IPHOHMKD_01231 8.08e-133 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
IPHOHMKD_01232 6.52e-270 arcT - - E - - - Aminotransferase
IPHOHMKD_01233 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
IPHOHMKD_01234 2.43e-18 - - - - - - - -
IPHOHMKD_01235 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IPHOHMKD_01236 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
IPHOHMKD_01237 3.67e-295 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
IPHOHMKD_01238 0.0 yhaN - - L - - - AAA domain
IPHOHMKD_01239 1.4e-238 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
IPHOHMKD_01240 6.15e-275 - - - - - - - -
IPHOHMKD_01241 5.44e-230 - - - M - - - Peptidase family S41
IPHOHMKD_01242 6.59e-227 - - - K - - - LysR substrate binding domain
IPHOHMKD_01243 4.71e-142 - - - S - - - NADPH-dependent FMN reductase
IPHOHMKD_01244 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
IPHOHMKD_01245 2.57e-128 - - - - - - - -
IPHOHMKD_01246 6.78e-100 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
IPHOHMKD_01247 9.45e-235 ykoT - - M - - - Glycosyl transferase family 2
IPHOHMKD_01248 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPHOHMKD_01249 4.29e-26 - - - S - - - NUDIX domain
IPHOHMKD_01250 0.0 - - - S - - - membrane
IPHOHMKD_01251 8.58e-218 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IPHOHMKD_01252 8.71e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
IPHOHMKD_01253 3.45e-283 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IPHOHMKD_01254 1.23e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IPHOHMKD_01255 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
IPHOHMKD_01256 3.39e-138 - - - - - - - -
IPHOHMKD_01257 3.3e-151 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
IPHOHMKD_01258 4.87e-60 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_01259 2.47e-66 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_01260 4.26e-308 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
IPHOHMKD_01261 0.0 - - - - - - - -
IPHOHMKD_01262 2.75e-79 - - - - - - - -
IPHOHMKD_01263 3.36e-248 - - - S - - - Fn3-like domain
IPHOHMKD_01264 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
IPHOHMKD_01265 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
IPHOHMKD_01266 1.6e-149 draG - - O - - - ADP-ribosylglycohydrolase
IPHOHMKD_01267 3.64e-195 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IPHOHMKD_01268 6.76e-73 - - - - - - - -
IPHOHMKD_01269 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
IPHOHMKD_01270 1.82e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_01271 2.01e-285 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
IPHOHMKD_01272 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
IPHOHMKD_01273 1.92e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IPHOHMKD_01274 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
IPHOHMKD_01275 1.45e-145 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IPHOHMKD_01276 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IPHOHMKD_01277 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
IPHOHMKD_01278 3.04e-29 - - - S - - - Virus attachment protein p12 family
IPHOHMKD_01279 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
IPHOHMKD_01280 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
IPHOHMKD_01281 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
IPHOHMKD_01282 5.21e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
IPHOHMKD_01283 6.39e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPHOHMKD_01284 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
IPHOHMKD_01285 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
IPHOHMKD_01286 1.54e-248 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IPHOHMKD_01287 4.63e-177 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IPHOHMKD_01288 1.14e-211 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPHOHMKD_01289 1.92e-106 - - - C - - - Flavodoxin
IPHOHMKD_01290 6.26e-92 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
IPHOHMKD_01291 7.86e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
IPHOHMKD_01292 3.92e-248 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IPHOHMKD_01293 1.98e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
IPHOHMKD_01294 4.08e-78 - - - S - - - Iron-sulfur cluster assembly protein
IPHOHMKD_01295 4.5e-202 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
IPHOHMKD_01296 2.16e-208 - - - H - - - geranyltranstransferase activity
IPHOHMKD_01297 6.4e-235 - - - - - - - -
IPHOHMKD_01298 2.13e-64 - - - - - - - -
IPHOHMKD_01299 5.46e-152 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
IPHOHMKD_01300 7e-243 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
IPHOHMKD_01301 3e-98 - 2.7.13.3 - T ko:K07683,ko:K10851 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 phosphoenolpyruvate-protein phosphotransferase activity
IPHOHMKD_01302 8.84e-52 - - - - - - - -
IPHOHMKD_01303 5.73e-129 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IPHOHMKD_01304 1.08e-111 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IPHOHMKD_01305 2.87e-117 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
IPHOHMKD_01306 1.28e-294 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
IPHOHMKD_01307 1.1e-107 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
IPHOHMKD_01308 1.12e-244 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
IPHOHMKD_01309 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IPHOHMKD_01310 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
IPHOHMKD_01311 8.2e-127 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
IPHOHMKD_01312 2.69e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
IPHOHMKD_01313 9.65e-223 - - - - - - - -
IPHOHMKD_01314 2.55e-96 - - - - - - - -
IPHOHMKD_01315 4.22e-124 - - - S - - - Protein of unknown function (DUF2975)
IPHOHMKD_01316 6.66e-39 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
IPHOHMKD_01317 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
IPHOHMKD_01318 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPHOHMKD_01319 3.19e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IPHOHMKD_01320 9.54e-134 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IPHOHMKD_01321 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IPHOHMKD_01322 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
IPHOHMKD_01323 6.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
IPHOHMKD_01324 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPHOHMKD_01325 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IPHOHMKD_01326 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
IPHOHMKD_01327 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IPHOHMKD_01328 2.58e-51 - - - - - - - -
IPHOHMKD_01329 8.2e-306 - - - L ko:K07478 - ko00000 AAA C-terminal domain
IPHOHMKD_01330 1.67e-250 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IPHOHMKD_01331 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
IPHOHMKD_01332 2.39e-175 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
IPHOHMKD_01333 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
IPHOHMKD_01334 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
IPHOHMKD_01335 3.81e-276 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
IPHOHMKD_01336 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
IPHOHMKD_01337 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IPHOHMKD_01338 1.71e-149 yqeK - - H - - - Hydrolase, HD family
IPHOHMKD_01339 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IPHOHMKD_01340 3.3e-180 yqeM - - Q - - - Methyltransferase
IPHOHMKD_01341 1.76e-279 ylbM - - S - - - Belongs to the UPF0348 family
IPHOHMKD_01342 5.19e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
IPHOHMKD_01343 1.77e-123 - - - S - - - Peptidase propeptide and YPEB domain
IPHOHMKD_01344 1.54e-223 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPHOHMKD_01345 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IPHOHMKD_01346 3.12e-311 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
IPHOHMKD_01347 1.38e-155 csrR - - K - - - response regulator
IPHOHMKD_01348 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IPHOHMKD_01349 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
IPHOHMKD_01350 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
IPHOHMKD_01351 2.36e-289 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IPHOHMKD_01352 1.77e-122 - - - S - - - SdpI/YhfL protein family
IPHOHMKD_01353 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IPHOHMKD_01354 2.36e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
IPHOHMKD_01355 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPHOHMKD_01356 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
IPHOHMKD_01357 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
IPHOHMKD_01358 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IPHOHMKD_01359 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IPHOHMKD_01360 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IPHOHMKD_01361 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
IPHOHMKD_01362 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IPHOHMKD_01363 5.38e-143 - - - S - - - membrane
IPHOHMKD_01364 2.33e-98 - - - K - - - LytTr DNA-binding domain
IPHOHMKD_01365 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
IPHOHMKD_01366 0.0 - - - S - - - membrane
IPHOHMKD_01367 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IPHOHMKD_01368 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IPHOHMKD_01369 9.29e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IPHOHMKD_01370 3.52e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
IPHOHMKD_01371 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
IPHOHMKD_01372 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
IPHOHMKD_01373 6.61e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
IPHOHMKD_01374 1.15e-89 yqhL - - P - - - Rhodanese-like protein
IPHOHMKD_01375 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
IPHOHMKD_01376 7.77e-179 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
IPHOHMKD_01377 2.29e-225 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IPHOHMKD_01378 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
IPHOHMKD_01379 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
IPHOHMKD_01380 4.17e-204 - - - - - - - -
IPHOHMKD_01381 5.46e-232 - - - - - - - -
IPHOHMKD_01382 2.92e-126 - - - S - - - Protein conserved in bacteria
IPHOHMKD_01383 3.11e-73 - - - - - - - -
IPHOHMKD_01384 2.97e-41 - - - - - - - -
IPHOHMKD_01387 9.81e-27 - - - - - - - -
IPHOHMKD_01388 8.15e-125 - - - K - - - Transcriptional regulator
IPHOHMKD_01389 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
IPHOHMKD_01390 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
IPHOHMKD_01391 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
IPHOHMKD_01392 3.49e-248 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
IPHOHMKD_01393 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IPHOHMKD_01394 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
IPHOHMKD_01395 1.63e-90 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IPHOHMKD_01396 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IPHOHMKD_01397 3.82e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IPHOHMKD_01398 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IPHOHMKD_01399 6.68e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IPHOHMKD_01400 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
IPHOHMKD_01401 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
IPHOHMKD_01402 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
IPHOHMKD_01403 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_01404 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IPHOHMKD_01405 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IPHOHMKD_01406 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IPHOHMKD_01407 8.28e-73 - - - - - - - -
IPHOHMKD_01408 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
IPHOHMKD_01409 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IPHOHMKD_01410 2.05e-277 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IPHOHMKD_01411 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IPHOHMKD_01412 1.01e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IPHOHMKD_01413 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IPHOHMKD_01414 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
IPHOHMKD_01415 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
IPHOHMKD_01416 2.33e-207 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IPHOHMKD_01417 1.29e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
IPHOHMKD_01418 3.57e-158 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
IPHOHMKD_01419 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
IPHOHMKD_01420 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
IPHOHMKD_01421 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
IPHOHMKD_01422 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IPHOHMKD_01423 2.17e-244 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IPHOHMKD_01424 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPHOHMKD_01425 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IPHOHMKD_01426 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
IPHOHMKD_01427 7.71e-298 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IPHOHMKD_01428 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IPHOHMKD_01429 9.38e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IPHOHMKD_01430 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
IPHOHMKD_01431 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
IPHOHMKD_01432 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IPHOHMKD_01433 1.83e-178 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
IPHOHMKD_01434 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IPHOHMKD_01435 1.03e-66 - - - - - - - -
IPHOHMKD_01436 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
IPHOHMKD_01437 9.06e-112 - - - - - - - -
IPHOHMKD_01438 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IPHOHMKD_01439 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
IPHOHMKD_01441 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
IPHOHMKD_01442 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
IPHOHMKD_01443 7.03e-225 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IPHOHMKD_01444 9.6e-156 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
IPHOHMKD_01445 6.4e-142 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
IPHOHMKD_01446 1.79e-287 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IPHOHMKD_01447 1.96e-182 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IPHOHMKD_01448 1.69e-125 entB - - Q - - - Isochorismatase family
IPHOHMKD_01449 3.53e-227 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
IPHOHMKD_01450 4.59e-87 ybbJ - - K - - - Acetyltransferase (GNAT) family
IPHOHMKD_01451 4.48e-179 - - - E - - - glutamate:sodium symporter activity
IPHOHMKD_01452 2.7e-82 - - - E - - - glutamate:sodium symporter activity
IPHOHMKD_01453 1.8e-127 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
IPHOHMKD_01454 7.18e-128 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
IPHOHMKD_01455 3.27e-253 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
IPHOHMKD_01456 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_01457 3.13e-99 - - - L - - - Transposase DDE domain
IPHOHMKD_01458 5.19e-78 - - - S - - - Protein of unknown function (DUF1648)
IPHOHMKD_01460 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IPHOHMKD_01461 1.62e-229 yneE - - K - - - Transcriptional regulator
IPHOHMKD_01462 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IPHOHMKD_01463 4.64e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPHOHMKD_01464 1.06e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPHOHMKD_01465 1.21e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
IPHOHMKD_01466 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IPHOHMKD_01467 5.38e-290 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IPHOHMKD_01468 2.14e-95 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IPHOHMKD_01469 1.71e-91 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
IPHOHMKD_01470 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
IPHOHMKD_01471 2.62e-202 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IPHOHMKD_01472 4.82e-179 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
IPHOHMKD_01473 2.29e-175 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
IPHOHMKD_01474 5.01e-129 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
IPHOHMKD_01475 4.95e-160 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
IPHOHMKD_01476 7.52e-207 - - - K - - - LysR substrate binding domain
IPHOHMKD_01477 2.01e-113 ykhA - - I - - - Thioesterase superfamily
IPHOHMKD_01478 3.61e-245 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IPHOHMKD_01479 1.22e-120 - - - K - - - transcriptional regulator
IPHOHMKD_01480 0.0 - - - EGP - - - Major Facilitator
IPHOHMKD_01481 1.14e-193 - - - O - - - Band 7 protein
IPHOHMKD_01482 8.58e-71 - - - - - - - -
IPHOHMKD_01483 2.02e-39 - - - - - - - -
IPHOHMKD_01484 1.69e-276 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
IPHOHMKD_01485 1.31e-103 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
IPHOHMKD_01486 5.93e-60 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
IPHOHMKD_01487 2.05e-55 - - - - - - - -
IPHOHMKD_01488 2.18e-245 - - - L - - - Transposase and inactivated derivatives, IS30 family
IPHOHMKD_01489 6.05e-108 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
IPHOHMKD_01490 5.28e-100 - - - T - - - Belongs to the universal stress protein A family
IPHOHMKD_01491 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
IPHOHMKD_01492 3.6e-211 - - - I - - - Diacylglycerol kinase catalytic domain
IPHOHMKD_01493 6.16e-48 - - - - - - - -
IPHOHMKD_01494 5.79e-21 - - - - - - - -
IPHOHMKD_01495 9.05e-55 - - - S - - - transglycosylase associated protein
IPHOHMKD_01496 4e-40 - - - S - - - CsbD-like
IPHOHMKD_01497 1.06e-53 - - - - - - - -
IPHOHMKD_01498 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
IPHOHMKD_01499 8.39e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
IPHOHMKD_01500 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IPHOHMKD_01501 6.03e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
IPHOHMKD_01502 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
IPHOHMKD_01503 7.52e-61 - - - - - - - -
IPHOHMKD_01504 6.78e-60 - - - - - - - -
IPHOHMKD_01505 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPHOHMKD_01506 0.0 - - - E ko:K03294 - ko00000 Amino Acid
IPHOHMKD_01507 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
IPHOHMKD_01508 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
IPHOHMKD_01509 8.83e-153 - - - S - - - Domain of unknown function (DUF4767)
IPHOHMKD_01511 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
IPHOHMKD_01512 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
IPHOHMKD_01513 3.36e-247 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
IPHOHMKD_01514 7.08e-250 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IPHOHMKD_01515 1.03e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
IPHOHMKD_01516 1.05e-228 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
IPHOHMKD_01517 1.72e-216 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
IPHOHMKD_01518 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
IPHOHMKD_01519 2.53e-107 ypmB - - S - - - protein conserved in bacteria
IPHOHMKD_01520 2.55e-288 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IPHOHMKD_01521 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
IPHOHMKD_01522 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
IPHOHMKD_01524 1.28e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IPHOHMKD_01525 2.45e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IPHOHMKD_01526 1.58e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
IPHOHMKD_01527 5.32e-109 - - - T - - - Universal stress protein family
IPHOHMKD_01528 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IPHOHMKD_01529 1.98e-234 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IPHOHMKD_01530 8.03e-229 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
IPHOHMKD_01531 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
IPHOHMKD_01532 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IPHOHMKD_01533 1.23e-141 ypsA - - S - - - Belongs to the UPF0398 family
IPHOHMKD_01534 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IPHOHMKD_01536 1.44e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
IPHOHMKD_01537 1.26e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IPHOHMKD_01538 3.13e-309 - - - P - - - Major Facilitator Superfamily
IPHOHMKD_01539 9.83e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IPHOHMKD_01540 9.19e-95 - - - S - - - SnoaL-like domain
IPHOHMKD_01541 9.63e-307 - - - M - - - Glycosyltransferase, group 2 family protein
IPHOHMKD_01542 1.16e-265 mccF - - V - - - LD-carboxypeptidase
IPHOHMKD_01543 1.66e-101 - - - K - - - Acetyltransferase (GNAT) domain
IPHOHMKD_01544 1.23e-311 - - - M ko:K07273 - ko00000 hydrolase, family 25
IPHOHMKD_01545 1.38e-232 - - - V - - - LD-carboxypeptidase
IPHOHMKD_01546 4.35e-159 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
IPHOHMKD_01547 1.9e-156 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IPHOHMKD_01548 2.27e-247 - - - - - - - -
IPHOHMKD_01549 3.69e-187 - - - S - - - hydrolase activity, acting on ester bonds
IPHOHMKD_01550 2.44e-267 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
IPHOHMKD_01551 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
IPHOHMKD_01552 5.89e-81 esbA - - S - - - Family of unknown function (DUF5322)
IPHOHMKD_01553 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
IPHOHMKD_01554 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IPHOHMKD_01555 2.79e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IPHOHMKD_01556 1.9e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IPHOHMKD_01557 1.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
IPHOHMKD_01558 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
IPHOHMKD_01559 2.01e-145 - - - G - - - Phosphoglycerate mutase family
IPHOHMKD_01560 4.62e-51 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IPHOHMKD_01561 3.2e-10 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IPHOHMKD_01564 2.24e-167 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
IPHOHMKD_01565 8.49e-92 - - - S - - - LuxR family transcriptional regulator
IPHOHMKD_01566 3.42e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
IPHOHMKD_01568 2.19e-116 - - - F - - - NUDIX domain
IPHOHMKD_01569 3.07e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_01570 3.78e-170 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IPHOHMKD_01571 0.0 FbpA - - K - - - Fibronectin-binding protein
IPHOHMKD_01572 1.97e-87 - - - K - - - Transcriptional regulator
IPHOHMKD_01573 1.11e-205 - - - S - - - EDD domain protein, DegV family
IPHOHMKD_01574 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
IPHOHMKD_01575 8.31e-170 - - - S - - - Protein of unknown function (DUF975)
IPHOHMKD_01576 3.15e-29 - - - - - - - -
IPHOHMKD_01577 1.67e-65 - - - - - - - -
IPHOHMKD_01578 5.69e-190 - - - C - - - Domain of unknown function (DUF4931)
IPHOHMKD_01579 6e-268 pmrB - - EGP - - - Major Facilitator Superfamily
IPHOHMKD_01581 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
IPHOHMKD_01582 9.3e-167 yejC - - S - - - Protein of unknown function (DUF1003)
IPHOHMKD_01583 2.59e-177 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
IPHOHMKD_01584 1.29e-313 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
IPHOHMKD_01585 3.26e-180 - - - - - - - -
IPHOHMKD_01586 7.79e-78 - - - - - - - -
IPHOHMKD_01587 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IPHOHMKD_01588 8.23e-291 - - - - - - - -
IPHOHMKD_01589 2.13e-151 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
IPHOHMKD_01590 1.31e-246 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
IPHOHMKD_01591 8.63e-275 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IPHOHMKD_01592 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IPHOHMKD_01593 1.4e-122 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IPHOHMKD_01594 1.48e-98 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IPHOHMKD_01595 0.0 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
IPHOHMKD_01596 3.22e-87 - - - - - - - -
IPHOHMKD_01597 4.49e-315 - - - M - - - Glycosyl transferase family group 2
IPHOHMKD_01598 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPHOHMKD_01599 2.18e-245 - - - L - - - Transposase and inactivated derivatives, IS30 family
IPHOHMKD_01600 3.59e-204 - - - L - - - Phage integrase, N-terminal SAM-like domain
IPHOHMKD_01601 1.07e-43 - - - S - - - YozE SAM-like fold
IPHOHMKD_01602 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPHOHMKD_01603 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
IPHOHMKD_01604 3.21e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
IPHOHMKD_01605 3.82e-228 - - - K - - - Transcriptional regulator
IPHOHMKD_01606 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IPHOHMKD_01607 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IPHOHMKD_01608 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IPHOHMKD_01609 4.24e-216 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
IPHOHMKD_01610 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IPHOHMKD_01611 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IPHOHMKD_01612 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
IPHOHMKD_01613 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IPHOHMKD_01614 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IPHOHMKD_01615 8.11e-203 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
IPHOHMKD_01616 2.89e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPHOHMKD_01617 1.85e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IPHOHMKD_01619 7.29e-292 XK27_05470 - - E - - - Methionine synthase
IPHOHMKD_01620 7.05e-219 cpsY - - K - - - Transcriptional regulator, LysR family
IPHOHMKD_01621 5.01e-160 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
IPHOHMKD_01622 1.28e-254 XK27_00915 - - C - - - Luciferase-like monooxygenase
IPHOHMKD_01623 0.0 qacA - - EGP - - - Major Facilitator
IPHOHMKD_01624 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IPHOHMKD_01625 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
IPHOHMKD_01626 1.1e-145 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
IPHOHMKD_01627 4.44e-204 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
IPHOHMKD_01628 2.03e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
IPHOHMKD_01629 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IPHOHMKD_01630 6.7e-241 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IPHOHMKD_01631 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_01632 6.46e-109 - - - - - - - -
IPHOHMKD_01633 1.73e-289 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IPHOHMKD_01634 1.39e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IPHOHMKD_01635 9.1e-193 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
IPHOHMKD_01636 6.8e-290 XK27_05225 - - S - - - Tetratricopeptide repeat protein
IPHOHMKD_01637 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IPHOHMKD_01638 4.84e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
IPHOHMKD_01639 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
IPHOHMKD_01640 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
IPHOHMKD_01641 5e-39 - - - M - - - Lysin motif
IPHOHMKD_01642 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
IPHOHMKD_01643 3.11e-248 - - - S - - - Helix-turn-helix domain
IPHOHMKD_01644 2.24e-126 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IPHOHMKD_01645 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IPHOHMKD_01646 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IPHOHMKD_01647 7.1e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IPHOHMKD_01648 5.67e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPHOHMKD_01649 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
IPHOHMKD_01650 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
IPHOHMKD_01651 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
IPHOHMKD_01652 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
IPHOHMKD_01653 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IPHOHMKD_01654 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
IPHOHMKD_01655 2.02e-39 - - - S - - - Protein of unknown function (DUF2929)
IPHOHMKD_01656 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IPHOHMKD_01657 3.17e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
IPHOHMKD_01658 4.42e-249 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IPHOHMKD_01659 5.63e-163 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
IPHOHMKD_01660 8.29e-294 - - - M - - - O-Antigen ligase
IPHOHMKD_01661 1.78e-165 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IPHOHMKD_01662 4.02e-211 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IPHOHMKD_01663 1.11e-111 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IPHOHMKD_01664 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IPHOHMKD_01665 2.65e-81 - - - P - - - Rhodanese Homology Domain
IPHOHMKD_01666 7.43e-119 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
IPHOHMKD_01667 1.59e-265 - - - - - - - -
IPHOHMKD_01668 7.4e-278 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
IPHOHMKD_01669 1.44e-230 - - - C - - - Zinc-binding dehydrogenase
IPHOHMKD_01670 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
IPHOHMKD_01671 1.09e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IPHOHMKD_01672 2.18e-305 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
IPHOHMKD_01673 4.38e-102 - - - K - - - Transcriptional regulator
IPHOHMKD_01674 6.74e-267 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
IPHOHMKD_01675 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IPHOHMKD_01676 5.87e-177 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
IPHOHMKD_01677 1.46e-139 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
IPHOHMKD_01678 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
IPHOHMKD_01679 1.56e-90 - - - S - - - Protein of unknown function (DUF1722)
IPHOHMKD_01680 4.68e-145 - - - GM - - - epimerase
IPHOHMKD_01681 0.0 - - - S - - - Zinc finger, swim domain protein
IPHOHMKD_01682 9.07e-158 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
IPHOHMKD_01683 2.7e-131 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
IPHOHMKD_01684 2.49e-167 - - - K - - - Helix-turn-helix domain, rpiR family
IPHOHMKD_01685 2.63e-206 - - - S - - - Alpha beta hydrolase
IPHOHMKD_01686 1.97e-143 - - - GM - - - NmrA-like family
IPHOHMKD_01687 1.74e-101 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
IPHOHMKD_01688 5.72e-207 - - - K - - - Transcriptional regulator
IPHOHMKD_01689 5.15e-219 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
IPHOHMKD_01691 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IPHOHMKD_01692 1.51e-132 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
IPHOHMKD_01693 2.49e-257 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IPHOHMKD_01694 1.66e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IPHOHMKD_01695 3.43e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IPHOHMKD_01697 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IPHOHMKD_01698 1.62e-100 - - - K - - - MarR family
IPHOHMKD_01699 4.27e-147 - - - S - - - Psort location CytoplasmicMembrane, score
IPHOHMKD_01700 0.000523 yjdF - - S - - - Protein of unknown function (DUF2992)
IPHOHMKD_01701 1.77e-207 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_01702 2.87e-168 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IPHOHMKD_01703 2.48e-252 - - - - - - - -
IPHOHMKD_01704 1.28e-256 - - - - - - - -
IPHOHMKD_01705 8.19e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_01706 6.86e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
IPHOHMKD_01707 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IPHOHMKD_01708 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IPHOHMKD_01709 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
IPHOHMKD_01710 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
IPHOHMKD_01711 2.33e-188 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
IPHOHMKD_01712 7.92e-217 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IPHOHMKD_01713 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
IPHOHMKD_01714 5.2e-108 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IPHOHMKD_01715 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
IPHOHMKD_01716 5.33e-93 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
IPHOHMKD_01717 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
IPHOHMKD_01718 6.65e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IPHOHMKD_01719 2.11e-165 - - - C - - - Enoyl-(Acyl carrier protein) reductase
IPHOHMKD_01720 7.36e-220 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IPHOHMKD_01721 3.04e-283 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IPHOHMKD_01722 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IPHOHMKD_01723 3.71e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPHOHMKD_01724 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IPHOHMKD_01725 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
IPHOHMKD_01726 2.83e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
IPHOHMKD_01727 1.79e-211 - - - G - - - Fructosamine kinase
IPHOHMKD_01728 5.97e-151 yjcF - - J - - - HAD-hyrolase-like
IPHOHMKD_01729 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IPHOHMKD_01730 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IPHOHMKD_01731 1.22e-74 - - - - - - - -
IPHOHMKD_01732 5.18e-171 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IPHOHMKD_01733 1.18e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
IPHOHMKD_01734 1.59e-83 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
IPHOHMKD_01735 1.17e-47 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
IPHOHMKD_01736 4.78e-65 - - - - - - - -
IPHOHMKD_01737 1e-66 - - - - - - - -
IPHOHMKD_01738 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IPHOHMKD_01739 6.83e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IPHOHMKD_01740 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPHOHMKD_01741 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
IPHOHMKD_01742 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPHOHMKD_01743 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
IPHOHMKD_01744 1.38e-232 pbpX2 - - V - - - Beta-lactamase
IPHOHMKD_01745 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IPHOHMKD_01746 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
IPHOHMKD_01747 4.72e-113 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IPHOHMKD_01748 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IPHOHMKD_01749 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
IPHOHMKD_01750 1.07e-241 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
IPHOHMKD_01751 1.27e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IPHOHMKD_01752 3.2e-73 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IPHOHMKD_01753 1.47e-246 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
IPHOHMKD_01754 1.11e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IPHOHMKD_01755 4.01e-122 - - - - - - - -
IPHOHMKD_01756 3.01e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IPHOHMKD_01757 0.0 - - - G - - - Major Facilitator
IPHOHMKD_01758 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IPHOHMKD_01759 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IPHOHMKD_01760 3.28e-63 ylxQ - - J - - - ribosomal protein
IPHOHMKD_01761 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
IPHOHMKD_01762 2.31e-277 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
IPHOHMKD_01763 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
IPHOHMKD_01764 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPHOHMKD_01765 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IPHOHMKD_01766 3.81e-293 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
IPHOHMKD_01767 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
IPHOHMKD_01768 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPHOHMKD_01769 4e-112 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IPHOHMKD_01770 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
IPHOHMKD_01771 1.88e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IPHOHMKD_01772 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
IPHOHMKD_01773 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
IPHOHMKD_01774 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPHOHMKD_01775 9.79e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
IPHOHMKD_01776 7.36e-172 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
IPHOHMKD_01777 1.71e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
IPHOHMKD_01778 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
IPHOHMKD_01779 7.68e-48 ynzC - - S - - - UPF0291 protein
IPHOHMKD_01780 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IPHOHMKD_01781 7.8e-123 - - - - - - - -
IPHOHMKD_01782 6.35e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
IPHOHMKD_01783 4.79e-99 - - - - - - - -
IPHOHMKD_01784 3.13e-86 - - - - - - - -
IPHOHMKD_01785 1.14e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
IPHOHMKD_01786 2.19e-131 - - - L - - - Helix-turn-helix domain
IPHOHMKD_01787 1.89e-282 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
IPHOHMKD_01788 1.08e-40 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IPHOHMKD_01789 9.02e-127 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IPHOHMKD_01790 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IPHOHMKD_01791 9.7e-294 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
IPHOHMKD_01793 1.75e-43 - - - - - - - -
IPHOHMKD_01794 2.21e-178 - - - Q - - - Methyltransferase
IPHOHMKD_01795 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
IPHOHMKD_01796 1.66e-269 - - - EGP - - - Major facilitator Superfamily
IPHOHMKD_01797 1.25e-129 - - - K - - - Helix-turn-helix domain
IPHOHMKD_01798 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IPHOHMKD_01799 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
IPHOHMKD_01800 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
IPHOHMKD_01801 1.18e-178 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IPHOHMKD_01802 8.34e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IPHOHMKD_01803 6.62e-62 - - - - - - - -
IPHOHMKD_01804 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IPHOHMKD_01805 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
IPHOHMKD_01806 4.24e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IPHOHMKD_01807 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
IPHOHMKD_01808 6.43e-90 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
IPHOHMKD_01809 5.51e-173 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
IPHOHMKD_01810 0.0 cps4J - - S - - - MatE
IPHOHMKD_01811 3.4e-228 cps4I - - M - - - Glycosyltransferase like family 2
IPHOHMKD_01812 4.49e-296 - - - - - - - -
IPHOHMKD_01813 1.94e-244 cps4G - - M - - - Glycosyltransferase Family 4
IPHOHMKD_01814 4.67e-258 cps4F - - M - - - Glycosyl transferases group 1
IPHOHMKD_01815 3.31e-164 tuaA - - M - - - Bacterial sugar transferase
IPHOHMKD_01816 8.71e-231 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
IPHOHMKD_01817 2.25e-188 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
IPHOHMKD_01818 2.02e-156 ywqD - - D - - - Capsular exopolysaccharide family
IPHOHMKD_01819 8.45e-162 epsB - - M - - - biosynthesis protein
IPHOHMKD_01820 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IPHOHMKD_01821 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_01822 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
IPHOHMKD_01823 5.12e-31 - - - - - - - -
IPHOHMKD_01824 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
IPHOHMKD_01825 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
IPHOHMKD_01826 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
IPHOHMKD_01827 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IPHOHMKD_01828 3.75e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IPHOHMKD_01829 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPHOHMKD_01830 9.34e-201 - - - S - - - Tetratricopeptide repeat
IPHOHMKD_01831 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPHOHMKD_01832 5.25e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPHOHMKD_01833 3.68e-260 - - - EGP - - - Major Facilitator Superfamily
IPHOHMKD_01834 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IPHOHMKD_01835 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
IPHOHMKD_01836 4.18e-240 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
IPHOHMKD_01837 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
IPHOHMKD_01838 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
IPHOHMKD_01839 2.1e-161 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
IPHOHMKD_01840 1.05e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
IPHOHMKD_01841 2.99e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IPHOHMKD_01842 8.61e-132 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
IPHOHMKD_01843 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
IPHOHMKD_01844 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IPHOHMKD_01845 8.38e-260 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IPHOHMKD_01846 0.0 - - - - - - - -
IPHOHMKD_01847 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
IPHOHMKD_01848 2.48e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
IPHOHMKD_01849 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
IPHOHMKD_01850 2.15e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
IPHOHMKD_01851 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
IPHOHMKD_01852 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IPHOHMKD_01853 8.65e-228 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
IPHOHMKD_01854 1.21e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
IPHOHMKD_01855 1.13e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IPHOHMKD_01856 6.45e-111 - - - - - - - -
IPHOHMKD_01857 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
IPHOHMKD_01858 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPHOHMKD_01859 5.96e-241 ytlR - - I - - - Diacylglycerol kinase catalytic domain
IPHOHMKD_01860 2.16e-39 - - - - - - - -
IPHOHMKD_01861 2.62e-168 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
IPHOHMKD_01862 5.35e-220 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IPHOHMKD_01863 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IPHOHMKD_01864 1.02e-155 - - - S - - - repeat protein
IPHOHMKD_01865 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
IPHOHMKD_01866 0.0 - - - N - - - domain, Protein
IPHOHMKD_01867 1.22e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
IPHOHMKD_01868 4.17e-153 - - - N - - - WxL domain surface cell wall-binding
IPHOHMKD_01869 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
IPHOHMKD_01870 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
IPHOHMKD_01871 3.19e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IPHOHMKD_01872 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
IPHOHMKD_01873 1.06e-277 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
IPHOHMKD_01874 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IPHOHMKD_01875 7.74e-47 - - - - - - - -
IPHOHMKD_01876 1.43e-124 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
IPHOHMKD_01877 1.41e-241 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IPHOHMKD_01878 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPHOHMKD_01879 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
IPHOHMKD_01880 2.06e-187 ylmH - - S - - - S4 domain protein
IPHOHMKD_01881 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
IPHOHMKD_01882 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IPHOHMKD_01883 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IPHOHMKD_01884 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IPHOHMKD_01885 2.34e-208 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IPHOHMKD_01886 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IPHOHMKD_01887 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IPHOHMKD_01888 8.05e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPHOHMKD_01889 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IPHOHMKD_01890 2.85e-75 ftsL - - D - - - Cell division protein FtsL
IPHOHMKD_01891 1.74e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IPHOHMKD_01892 7.24e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
IPHOHMKD_01893 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
IPHOHMKD_01894 4.99e-224 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
IPHOHMKD_01895 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IPHOHMKD_01896 1.41e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IPHOHMKD_01897 1.76e-147 - - - S ko:K07118 - ko00000 NAD(P)H-binding
IPHOHMKD_01898 2.17e-302 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IPHOHMKD_01900 4.55e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
IPHOHMKD_01901 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPHOHMKD_01902 9.52e-264 XK27_05220 - - S - - - AI-2E family transporter
IPHOHMKD_01903 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
IPHOHMKD_01904 5.57e-247 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
IPHOHMKD_01905 2.51e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
IPHOHMKD_01906 1.27e-221 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IPHOHMKD_01907 5.27e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IPHOHMKD_01908 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
IPHOHMKD_01909 2.24e-148 yjbH - - Q - - - Thioredoxin
IPHOHMKD_01910 3.86e-256 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IPHOHMKD_01911 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
IPHOHMKD_01912 4.53e-264 coiA - - S ko:K06198 - ko00000 Competence protein
IPHOHMKD_01913 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IPHOHMKD_01914 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IPHOHMKD_01915 2.81e-178 yhfI - - S - - - Metallo-beta-lactamase superfamily
IPHOHMKD_01916 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
IPHOHMKD_01938 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
IPHOHMKD_01939 7.5e-83 - - - - - - - -
IPHOHMKD_01940 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
IPHOHMKD_01941 2.1e-140 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPHOHMKD_01942 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
IPHOHMKD_01943 5.48e-150 - - - S - - - Protein of unknown function (DUF1461)
IPHOHMKD_01944 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IPHOHMKD_01945 1.96e-116 yutD - - S - - - Protein of unknown function (DUF1027)
IPHOHMKD_01946 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IPHOHMKD_01947 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
IPHOHMKD_01948 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
IPHOHMKD_01949 3.86e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPHOHMKD_01950 4.29e-237 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
IPHOHMKD_01952 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
IPHOHMKD_01953 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
IPHOHMKD_01954 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
IPHOHMKD_01955 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
IPHOHMKD_01956 7.23e-241 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
IPHOHMKD_01957 4.25e-223 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
IPHOHMKD_01958 4.15e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPHOHMKD_01959 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
IPHOHMKD_01960 2.34e-63 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
IPHOHMKD_01961 4.56e-210 - - - G - - - Xylose isomerase domain protein TIM barrel
IPHOHMKD_01962 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
IPHOHMKD_01963 1.55e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
IPHOHMKD_01964 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
IPHOHMKD_01965 1.6e-96 - - - - - - - -
IPHOHMKD_01966 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IPHOHMKD_01967 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
IPHOHMKD_01968 7.85e-288 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IPHOHMKD_01969 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IPHOHMKD_01970 7.94e-114 ykuL - - S - - - (CBS) domain
IPHOHMKD_01971 1.07e-120 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
IPHOHMKD_01972 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IPHOHMKD_01973 8.74e-195 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IPHOHMKD_01974 2.57e-118 yslB - - S - - - Protein of unknown function (DUF2507)
IPHOHMKD_01975 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
IPHOHMKD_01976 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IPHOHMKD_01977 4.33e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IPHOHMKD_01978 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
IPHOHMKD_01979 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IPHOHMKD_01980 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
IPHOHMKD_01981 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPHOHMKD_01982 2.79e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IPHOHMKD_01983 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
IPHOHMKD_01984 2.04e-275 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPHOHMKD_01985 1.32e-63 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
IPHOHMKD_01986 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IPHOHMKD_01987 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IPHOHMKD_01988 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IPHOHMKD_01989 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IPHOHMKD_01990 4.02e-114 - - - - - - - -
IPHOHMKD_01991 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
IPHOHMKD_01992 1.35e-93 - - - - - - - -
IPHOHMKD_01993 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IPHOHMKD_01994 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IPHOHMKD_01995 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
IPHOHMKD_01996 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
IPHOHMKD_01997 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IPHOHMKD_01998 4.47e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
IPHOHMKD_01999 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IPHOHMKD_02000 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
IPHOHMKD_02001 0.0 ymfH - - S - - - Peptidase M16
IPHOHMKD_02002 3.55e-296 ymfF - - S - - - Peptidase M16 inactive domain protein
IPHOHMKD_02003 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IPHOHMKD_02004 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
IPHOHMKD_02005 9.09e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_02006 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
IPHOHMKD_02007 3.54e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
IPHOHMKD_02008 3.81e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IPHOHMKD_02009 1.91e-114 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
IPHOHMKD_02010 7.58e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
IPHOHMKD_02011 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
IPHOHMKD_02012 2.23e-69 radC - - L ko:K03630 - ko00000 DNA repair protein
IPHOHMKD_02013 2.42e-69 radC - - L ko:K03630 - ko00000 DNA repair protein
IPHOHMKD_02014 7.76e-314 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
IPHOHMKD_02015 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IPHOHMKD_02016 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IPHOHMKD_02017 1.35e-300 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
IPHOHMKD_02018 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IPHOHMKD_02019 7.42e-277 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
IPHOHMKD_02020 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IPHOHMKD_02021 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
IPHOHMKD_02022 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IPHOHMKD_02023 2.32e-144 yktB - - S - - - Belongs to the UPF0637 family
IPHOHMKD_02024 1.15e-104 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
IPHOHMKD_02025 1.57e-142 - - - S - - - Protein of unknown function (DUF1648)
IPHOHMKD_02026 5.51e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IPHOHMKD_02027 7.24e-291 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IPHOHMKD_02028 3.43e-55 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
IPHOHMKD_02029 5.82e-139 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
IPHOHMKD_02030 3.72e-131 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
IPHOHMKD_02031 3.79e-85 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
IPHOHMKD_02032 1.31e-119 - - - K - - - Periplasmic binding proteins and sugar binding domain of LacI family
IPHOHMKD_02033 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
IPHOHMKD_02034 2.08e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
IPHOHMKD_02035 1.34e-52 - - - - - - - -
IPHOHMKD_02036 2.37e-107 uspA - - T - - - universal stress protein
IPHOHMKD_02037 8.1e-261 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
IPHOHMKD_02038 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
IPHOHMKD_02039 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
IPHOHMKD_02040 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
IPHOHMKD_02041 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IPHOHMKD_02042 3.26e-227 - - - S - - - Protein of unknown function (DUF2785)
IPHOHMKD_02043 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
IPHOHMKD_02044 4.24e-182 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
IPHOHMKD_02045 2.01e-149 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
IPHOHMKD_02046 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IPHOHMKD_02047 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
IPHOHMKD_02048 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
IPHOHMKD_02049 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
IPHOHMKD_02050 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
IPHOHMKD_02051 1.68e-229 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
IPHOHMKD_02052 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IPHOHMKD_02053 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPHOHMKD_02054 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
IPHOHMKD_02055 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IPHOHMKD_02056 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IPHOHMKD_02057 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPHOHMKD_02058 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPHOHMKD_02059 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IPHOHMKD_02060 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPHOHMKD_02061 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
IPHOHMKD_02062 5.86e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
IPHOHMKD_02063 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IPHOHMKD_02064 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IPHOHMKD_02065 1.92e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IPHOHMKD_02066 2.33e-202 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IPHOHMKD_02067 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IPHOHMKD_02068 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
IPHOHMKD_02069 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
IPHOHMKD_02070 1.83e-175 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
IPHOHMKD_02071 4.07e-249 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IPHOHMKD_02072 7.59e-245 ampC - - V - - - Beta-lactamase
IPHOHMKD_02073 8.57e-41 - - - - - - - -
IPHOHMKD_02074 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IPHOHMKD_02075 1.33e-77 - - - - - - - -
IPHOHMKD_02076 6.55e-183 - - - - - - - -
IPHOHMKD_02077 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
IPHOHMKD_02078 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_02079 1.81e-85 yxeA - - S - - - Protein of unknown function (DUF1093)
IPHOHMKD_02080 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
IPHOHMKD_02082 1.06e-24 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
IPHOHMKD_02083 8.87e-28 - - - T ko:K07172 - ko00000,ko02048 SpoVT / AbrB like domain
IPHOHMKD_02084 1.15e-57 - - - S - - - Bacteriophage holin
IPHOHMKD_02085 2.17e-62 - - - - - - - -
IPHOHMKD_02086 1.63e-234 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
IPHOHMKD_02089 9.98e-203 - - - S - - - Prophage endopeptidase tail
IPHOHMKD_02090 7.01e-156 - - - S - - - Phage tail protein
IPHOHMKD_02091 0.0 - - - S - - - peptidoglycan catabolic process
IPHOHMKD_02092 1.73e-132 - - - S - - - Bacteriophage Gp15 protein
IPHOHMKD_02094 1.76e-102 - - - - - - - -
IPHOHMKD_02095 1.53e-88 - - - S - - - Minor capsid protein from bacteriophage
IPHOHMKD_02096 1.84e-65 - - - S - - - Minor capsid protein
IPHOHMKD_02097 1.06e-71 - - - S - - - Minor capsid protein
IPHOHMKD_02098 1.56e-11 - - - - - - - -
IPHOHMKD_02099 9.39e-129 - - - - - - - -
IPHOHMKD_02100 2.47e-86 - - - S - - - Phage minor structural protein GP20
IPHOHMKD_02101 3.46e-217 - - - S - - - Phage minor capsid protein 2
IPHOHMKD_02102 3.07e-309 - - - S - - - Phage portal protein, SPP1 Gp6-like
IPHOHMKD_02103 0.0 - - - S - - - Phage terminase large subunit
IPHOHMKD_02104 4.25e-99 - - - L ko:K07474 - ko00000 Terminase small subunit
IPHOHMKD_02105 3.98e-37 - - - - - - - -
IPHOHMKD_02106 4.3e-52 - - - S - - - Beta protein
IPHOHMKD_02107 7.9e-54 - - - S - - - Psort location Cytoplasmic, score
IPHOHMKD_02110 2.99e-35 - - - - - - - -
IPHOHMKD_02111 9.94e-27 - - - S - - - YopX protein
IPHOHMKD_02113 6.67e-86 - - - L - - - Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IPHOHMKD_02114 1.34e-114 - - - - - - - -
IPHOHMKD_02115 2.2e-65 - - - - - - - -
IPHOHMKD_02116 1.53e-199 - - - L - - - DnaD domain protein
IPHOHMKD_02117 1.57e-80 - - - - - - - -
IPHOHMKD_02118 2.8e-70 - - - S - - - Bacteriophage Mu Gam like protein
IPHOHMKD_02121 6.09e-101 - - - - - - - -
IPHOHMKD_02122 1.56e-70 - - - - - - - -
IPHOHMKD_02124 1.33e-06 - - - K - - - Helix-turn-helix XRE-family like proteins
IPHOHMKD_02125 2.94e-22 - - - K ko:K22299 - ko00000,ko03000 sequence-specific DNA binding
IPHOHMKD_02128 1.23e-232 - - - S ko:K07504 - ko00000 Type I restriction enzyme R protein N terminus (HSDR_N)
IPHOHMKD_02132 0.0 - - - S - - - AAA ATPase domain
IPHOHMKD_02133 8.98e-224 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 DNA methyltransferase
IPHOHMKD_02134 1.33e-278 int3 - - L - - - Belongs to the 'phage' integrase family
IPHOHMKD_02136 1.98e-40 - - - - - - - -
IPHOHMKD_02138 1.28e-51 - - - - - - - -
IPHOHMKD_02139 1.87e-57 - - - - - - - -
IPHOHMKD_02140 1.27e-109 - - - K - - - MarR family
IPHOHMKD_02141 0.0 - - - D - - - nuclear chromosome segregation
IPHOHMKD_02142 1.47e-216 inlJ - - M - - - MucBP domain
IPHOHMKD_02143 9.05e-22 - - - - - - - -
IPHOHMKD_02144 2.69e-23 - - - - - - - -
IPHOHMKD_02145 9.85e-22 - - - - - - - -
IPHOHMKD_02146 6.21e-26 - - - - - - - -
IPHOHMKD_02147 1.07e-26 - - - - - - - -
IPHOHMKD_02148 2.16e-26 - - - - - - - -
IPHOHMKD_02149 4.63e-24 - - - - - - - -
IPHOHMKD_02150 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
IPHOHMKD_02151 2.35e-77 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IPHOHMKD_02152 5.42e-254 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IPHOHMKD_02153 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_02154 2.1e-33 - - - - - - - -
IPHOHMKD_02155 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
IPHOHMKD_02156 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
IPHOHMKD_02157 1.83e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
IPHOHMKD_02158 0.0 yclK - - T - - - Histidine kinase
IPHOHMKD_02159 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
IPHOHMKD_02160 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
IPHOHMKD_02161 6.12e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
IPHOHMKD_02162 1.26e-218 - - - EG - - - EamA-like transporter family
IPHOHMKD_02164 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
IPHOHMKD_02165 1.31e-64 - - - - - - - -
IPHOHMKD_02166 2.28e-272 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
IPHOHMKD_02167 8.05e-178 - - - F - - - NUDIX domain
IPHOHMKD_02168 2.68e-32 - - - - - - - -
IPHOHMKD_02170 2e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
IPHOHMKD_02171 4.27e-223 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
IPHOHMKD_02172 3.43e-106 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
IPHOHMKD_02173 9.33e-48 - - - - - - - -
IPHOHMKD_02174 4.54e-45 - - - - - - - -
IPHOHMKD_02175 8.05e-278 - - - T - - - diguanylate cyclase
IPHOHMKD_02176 0.0 - - - S - - - ABC transporter, ATP-binding protein
IPHOHMKD_02177 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
IPHOHMKD_02178 2.35e-106 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPHOHMKD_02179 2.64e-61 - - - - - - - -
IPHOHMKD_02180 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
IPHOHMKD_02181 1.31e-242 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPHOHMKD_02182 3.45e-209 - - - S - - - Uncharacterised protein, DegV family COG1307
IPHOHMKD_02183 1.38e-291 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
IPHOHMKD_02184 6.08e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
IPHOHMKD_02185 1.53e-213 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
IPHOHMKD_02186 9.31e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
IPHOHMKD_02187 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IPHOHMKD_02188 1.32e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_02189 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
IPHOHMKD_02190 1.35e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
IPHOHMKD_02191 1.18e-175 yceF - - P ko:K05794 - ko00000 membrane
IPHOHMKD_02192 1.74e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
IPHOHMKD_02193 1.83e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IPHOHMKD_02194 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
IPHOHMKD_02195 2.49e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IPHOHMKD_02196 1.27e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IPHOHMKD_02197 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IPHOHMKD_02198 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IPHOHMKD_02199 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
IPHOHMKD_02200 7.8e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IPHOHMKD_02201 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IPHOHMKD_02202 2.3e-275 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IPHOHMKD_02203 4.54e-208 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
IPHOHMKD_02204 3.72e-283 ysaA - - V - - - RDD family
IPHOHMKD_02205 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
IPHOHMKD_02206 6.7e-74 - - - S - - - Domain of unknown function (DU1801)
IPHOHMKD_02207 4.73e-118 rmeB - - K - - - transcriptional regulator, MerR family
IPHOHMKD_02208 1.39e-47 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IPHOHMKD_02209 2.87e-128 - - - GM - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IPHOHMKD_02210 3.74e-125 - - - J - - - glyoxalase III activity
IPHOHMKD_02211 1.69e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IPHOHMKD_02212 5.48e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IPHOHMKD_02213 3.42e-45 - - - - - - - -
IPHOHMKD_02214 3.1e-144 - - - S - - - Protein of unknown function (DUF1211)
IPHOHMKD_02215 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
IPHOHMKD_02216 0.0 - - - M - - - domain protein
IPHOHMKD_02217 6.05e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
IPHOHMKD_02218 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IPHOHMKD_02219 1.65e-74 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
IPHOHMKD_02220 9.44e-284 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
IPHOHMKD_02221 4.68e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
IPHOHMKD_02222 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
IPHOHMKD_02223 6.36e-244 - - - S - - - domain, Protein
IPHOHMKD_02224 4.96e-216 - - - S - - - Polyphosphate kinase 2 (PPK2)
IPHOHMKD_02225 3e-127 - - - C - - - Nitroreductase family
IPHOHMKD_02226 5.02e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
IPHOHMKD_02227 3.68e-203 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPHOHMKD_02228 2.2e-157 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
IPHOHMKD_02229 1.48e-201 ccpB - - K - - - lacI family
IPHOHMKD_02230 4.16e-150 - - - K - - - Helix-turn-helix domain, rpiR family
IPHOHMKD_02231 2.48e-227 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
IPHOHMKD_02232 1.05e-251 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
IPHOHMKD_02233 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
IPHOHMKD_02234 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IPHOHMKD_02235 9.38e-139 pncA - - Q - - - Isochorismatase family
IPHOHMKD_02236 2.66e-172 - - - - - - - -
IPHOHMKD_02237 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IPHOHMKD_02238 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
IPHOHMKD_02239 7.2e-61 - - - S - - - Enterocin A Immunity
IPHOHMKD_02240 5.39e-222 ybcH - - D ko:K06889 - ko00000 Alpha beta
IPHOHMKD_02241 0.0 pepF2 - - E - - - Oligopeptidase F
IPHOHMKD_02242 1.4e-95 - - - K - - - Transcriptional regulator
IPHOHMKD_02243 7.58e-210 - - - - - - - -
IPHOHMKD_02245 5.03e-75 - - - - - - - -
IPHOHMKD_02246 8.34e-65 - - - - - - - -
IPHOHMKD_02247 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IPHOHMKD_02248 2.37e-88 - - - - - - - -
IPHOHMKD_02249 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
IPHOHMKD_02250 9.89e-74 ytpP - - CO - - - Thioredoxin
IPHOHMKD_02251 6.69e-263 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
IPHOHMKD_02252 3.89e-62 - - - - - - - -
IPHOHMKD_02253 1.57e-71 - - - - - - - -
IPHOHMKD_02254 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
IPHOHMKD_02255 4.05e-98 - - - - - - - -
IPHOHMKD_02256 4.15e-78 - - - - - - - -
IPHOHMKD_02257 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
IPHOHMKD_02258 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
IPHOHMKD_02259 2.51e-103 uspA3 - - T - - - universal stress protein
IPHOHMKD_02260 2.92e-202 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IPHOHMKD_02261 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
IPHOHMKD_02262 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
IPHOHMKD_02263 3.07e-284 - - - M - - - Glycosyl transferases group 1
IPHOHMKD_02264 3.13e-99 - - - L - - - Transposase DDE domain
IPHOHMKD_02265 3.9e-88 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_02266 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
IPHOHMKD_02267 1.47e-211 - - - S - - - Putative esterase
IPHOHMKD_02268 3.53e-169 - - - K - - - Transcriptional regulator
IPHOHMKD_02269 6.74e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IPHOHMKD_02270 1.74e-178 - - - - - - - -
IPHOHMKD_02271 4.85e-151 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
IPHOHMKD_02272 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
IPHOHMKD_02273 2.41e-118 - - - K - - - Domain of unknown function (DUF1836)
IPHOHMKD_02274 2.2e-79 - - - - - - - -
IPHOHMKD_02275 2.61e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IPHOHMKD_02276 2.97e-76 - - - - - - - -
IPHOHMKD_02277 2.7e-314 yhdP - - S - - - Transporter associated domain
IPHOHMKD_02278 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
IPHOHMKD_02279 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
IPHOHMKD_02280 2.03e-271 yttB - - EGP - - - Major Facilitator
IPHOHMKD_02281 3.45e-83 - - - K - - - helix_turn_helix, mercury resistance
IPHOHMKD_02282 2.19e-220 - - - C - - - Zinc-binding dehydrogenase
IPHOHMKD_02283 4.71e-74 - - - S - - - SdpI/YhfL protein family
IPHOHMKD_02284 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IPHOHMKD_02285 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
IPHOHMKD_02286 1.02e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IPHOHMKD_02287 1.25e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPHOHMKD_02288 3.59e-26 - - - - - - - -
IPHOHMKD_02289 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
IPHOHMKD_02290 1.56e-39 mleR - - K - - - LysR family
IPHOHMKD_02291 1.52e-67 mleR - - K - - - LysR family
IPHOHMKD_02292 1.29e-148 - - - GM - - - NAD(P)H-binding
IPHOHMKD_02293 3.86e-124 - - - K - - - Acetyltransferase (GNAT) family
IPHOHMKD_02294 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
IPHOHMKD_02295 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IPHOHMKD_02296 1.12e-216 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
IPHOHMKD_02297 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IPHOHMKD_02298 1.55e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IPHOHMKD_02299 1.04e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IPHOHMKD_02300 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
IPHOHMKD_02301 2.76e-271 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IPHOHMKD_02302 1.61e-308 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IPHOHMKD_02303 2.02e-219 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
IPHOHMKD_02304 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IPHOHMKD_02305 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
IPHOHMKD_02306 4.41e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
IPHOHMKD_02307 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
IPHOHMKD_02308 2.24e-206 - - - GM - - - NmrA-like family
IPHOHMKD_02309 1.25e-199 - - - T - - - EAL domain
IPHOHMKD_02310 1.85e-121 - - - - - - - -
IPHOHMKD_02311 2.49e-241 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
IPHOHMKD_02312 1.38e-225 - - - L - - - Transposase and inactivated derivatives, IS30 family
IPHOHMKD_02313 4.1e-48 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
IPHOHMKD_02314 7.77e-159 - - - E - - - Methionine synthase
IPHOHMKD_02315 1.57e-279 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
IPHOHMKD_02316 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
IPHOHMKD_02317 5.35e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IPHOHMKD_02318 4.22e-243 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
IPHOHMKD_02319 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IPHOHMKD_02320 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPHOHMKD_02321 6.91e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPHOHMKD_02322 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPHOHMKD_02323 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
IPHOHMKD_02324 2.87e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IPHOHMKD_02325 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IPHOHMKD_02326 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
IPHOHMKD_02327 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
IPHOHMKD_02328 2.01e-243 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
IPHOHMKD_02329 4.81e-188 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
IPHOHMKD_02330 5.95e-153 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
IPHOHMKD_02331 6.89e-190 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
IPHOHMKD_02332 1.51e-232 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
IPHOHMKD_02333 2.05e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_02334 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
IPHOHMKD_02335 7.91e-55 - - - - - - - -
IPHOHMKD_02336 4.75e-80 - - - K - - - Transcriptional regulator, GntR family
IPHOHMKD_02337 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_02338 4.21e-175 - - - - - - - -
IPHOHMKD_02339 2.7e-104 usp5 - - T - - - universal stress protein
IPHOHMKD_02340 3.64e-46 - - - - - - - -
IPHOHMKD_02341 5.7e-95 gtcA - - S - - - Teichoic acid glycosylation protein
IPHOHMKD_02342 1.76e-114 - - - - - - - -
IPHOHMKD_02343 1.02e-67 - - - - - - - -
IPHOHMKD_02344 4.79e-13 - - - - - - - -
IPHOHMKD_02345 3.03e-299 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
IPHOHMKD_02346 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
IPHOHMKD_02347 1.52e-151 - - - - - - - -
IPHOHMKD_02348 1.21e-69 - - - - - - - -
IPHOHMKD_02350 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
IPHOHMKD_02351 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
IPHOHMKD_02352 1.89e-185 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
IPHOHMKD_02353 4.72e-40 - - - S - - - Pentapeptide repeats (8 copies)
IPHOHMKD_02354 4.99e-124 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
IPHOHMKD_02355 3.24e-132 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
IPHOHMKD_02356 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
IPHOHMKD_02357 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
IPHOHMKD_02358 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
IPHOHMKD_02359 9.97e-269 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
IPHOHMKD_02360 1.48e-292 - - - S - - - Sterol carrier protein domain
IPHOHMKD_02361 3.24e-204 - - - L ko:K07487 - ko00000 Transposase
IPHOHMKD_02362 7.87e-40 - - - L ko:K07487 - ko00000 Transposase
IPHOHMKD_02363 2.79e-225 - - - L - - - Transposase and inactivated derivatives, IS30 family
IPHOHMKD_02364 1.39e-108 - - - L ko:K07487 - ko00000 Transposase
IPHOHMKD_02366 5.12e-37 yvbK - - K - - - GNAT family
IPHOHMKD_02367 4.25e-198 - - - L ko:K07482 - ko00000 Integrase core domain
IPHOHMKD_02369 2.17e-25 - - - - - - - -
IPHOHMKD_02370 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_02371 3.13e-99 - - - L - - - Transposase DDE domain
IPHOHMKD_02372 3.6e-27 - - - - - - - -
IPHOHMKD_02373 3.56e-14 - - - K - - - Helix-turn-helix XRE-family like proteins
IPHOHMKD_02374 3.33e-244 - - - EGP - - - Transmembrane secretion effector
IPHOHMKD_02375 7.54e-115 yrxA - - S ko:K07105 - ko00000 3H domain
IPHOHMKD_02376 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IPHOHMKD_02377 2.13e-152 - - - K - - - Transcriptional regulator
IPHOHMKD_02378 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
IPHOHMKD_02379 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IPHOHMKD_02380 9.53e-317 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
IPHOHMKD_02381 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IPHOHMKD_02382 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IPHOHMKD_02383 2.73e-73 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
IPHOHMKD_02384 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
IPHOHMKD_02385 6.37e-169 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
IPHOHMKD_02386 1.4e-181 epsV - - S - - - glycosyl transferase family 2
IPHOHMKD_02387 7.15e-156 pgm7 - - G - - - Phosphoglycerate mutase family
IPHOHMKD_02388 7.63e-107 - - - - - - - -
IPHOHMKD_02389 5.06e-196 - - - S - - - hydrolase
IPHOHMKD_02390 1.51e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPHOHMKD_02391 2.8e-204 - - - EG - - - EamA-like transporter family
IPHOHMKD_02392 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IPHOHMKD_02393 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
IPHOHMKD_02394 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
IPHOHMKD_02395 2.35e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
IPHOHMKD_02396 0.0 - - - M - - - Domain of unknown function (DUF5011)
IPHOHMKD_02397 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
IPHOHMKD_02398 4.3e-44 - - - - - - - -
IPHOHMKD_02399 2.89e-165 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
IPHOHMKD_02400 0.0 ycaM - - E - - - amino acid
IPHOHMKD_02401 1.41e-100 - - - K - - - Winged helix DNA-binding domain
IPHOHMKD_02402 1.66e-211 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
IPHOHMKD_02403 5.11e-208 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
IPHOHMKD_02404 5.3e-209 - - - K - - - Transcriptional regulator
IPHOHMKD_02406 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
IPHOHMKD_02407 1.97e-110 - - - S - - - Pfam:DUF3816
IPHOHMKD_02408 1.21e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPHOHMKD_02409 1.27e-143 - - - - - - - -
IPHOHMKD_02410 6.24e-229 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
IPHOHMKD_02411 3.84e-185 - - - S - - - Peptidase_C39 like family
IPHOHMKD_02412 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
IPHOHMKD_02413 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
IPHOHMKD_02414 2.69e-188 - - - KT - - - helix_turn_helix, mercury resistance
IPHOHMKD_02415 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPHOHMKD_02416 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
IPHOHMKD_02417 3.44e-240 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
IPHOHMKD_02418 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_02419 2.27e-116 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
IPHOHMKD_02420 1.84e-234 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
IPHOHMKD_02421 3.55e-127 ywjB - - H - - - RibD C-terminal domain
IPHOHMKD_02422 1.62e-257 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IPHOHMKD_02423 8.64e-153 - - - S - - - Membrane
IPHOHMKD_02424 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
IPHOHMKD_02425 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
IPHOHMKD_02426 3.04e-261 - - - EGP - - - Major Facilitator Superfamily
IPHOHMKD_02427 9.46e-159 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IPHOHMKD_02428 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
IPHOHMKD_02429 2.43e-105 - - - S - - - Domain of unknown function (DUF4811)
IPHOHMKD_02430 3.66e-132 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IPHOHMKD_02431 2.17e-222 - - - S - - - Conserved hypothetical protein 698
IPHOHMKD_02432 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
IPHOHMKD_02433 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
IPHOHMKD_02434 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IPHOHMKD_02436 1.12e-86 - - - M - - - LysM domain
IPHOHMKD_02437 6.5e-119 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
IPHOHMKD_02438 2.45e-214 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_02439 7.88e-269 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IPHOHMKD_02440 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IPHOHMKD_02441 4.72e-72 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
IPHOHMKD_02442 4.77e-100 yphH - - S - - - Cupin domain
IPHOHMKD_02443 5.19e-103 - - - K - - - transcriptional regulator, MerR family
IPHOHMKD_02444 6.18e-301 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
IPHOHMKD_02445 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
IPHOHMKD_02446 4.09e-155 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_02448 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IPHOHMKD_02449 3.18e-141 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
IPHOHMKD_02450 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IPHOHMKD_02452 4.86e-111 - - - - - - - -
IPHOHMKD_02453 1.04e-110 yvbK - - K - - - GNAT family
IPHOHMKD_02454 9.4e-48 - - - - - - - -
IPHOHMKD_02455 2.81e-64 - - - - - - - -
IPHOHMKD_02456 7.44e-143 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
IPHOHMKD_02457 6.09e-83 - - - S - - - Domain of unknown function (DUF4440)
IPHOHMKD_02458 1.51e-200 - - - K - - - LysR substrate binding domain
IPHOHMKD_02459 1.52e-135 - - - GM - - - NAD(P)H-binding
IPHOHMKD_02460 6.77e-247 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
IPHOHMKD_02461 2.9e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IPHOHMKD_02462 1.28e-45 - - - - - - - -
IPHOHMKD_02463 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
IPHOHMKD_02464 2.09e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
IPHOHMKD_02465 1.76e-162 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IPHOHMKD_02466 1.03e-40 - - - - - - - -
IPHOHMKD_02467 5.52e-133 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
IPHOHMKD_02468 6.97e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
IPHOHMKD_02469 1.07e-131 - - - M - - - Protein of unknown function (DUF3737)
IPHOHMKD_02470 1.8e-249 - - - C - - - Aldo/keto reductase family
IPHOHMKD_02472 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IPHOHMKD_02473 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IPHOHMKD_02474 3.85e-315 - - - EGP - - - Major Facilitator
IPHOHMKD_02478 1.03e-314 yhgE - - V ko:K01421 - ko00000 domain protein
IPHOHMKD_02479 1.23e-123 - - - K - - - Transcriptional regulator (TetR family)
IPHOHMKD_02480 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IPHOHMKD_02481 5.29e-196 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
IPHOHMKD_02482 1.14e-133 yokL3 - - J - - - Acetyltransferase (GNAT) domain
IPHOHMKD_02483 3.05e-126 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IPHOHMKD_02484 1.85e-155 - - - M - - - Phosphotransferase enzyme family
IPHOHMKD_02485 2.34e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
IPHOHMKD_02486 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
IPHOHMKD_02487 1.9e-189 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
IPHOHMKD_02488 0.0 - - - S - - - Predicted membrane protein (DUF2207)
IPHOHMKD_02489 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
IPHOHMKD_02490 1.51e-92 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
IPHOHMKD_02491 3.94e-42 - - - EGP - - - Major facilitator Superfamily
IPHOHMKD_02492 3.13e-99 - - - L - - - Transposase DDE domain
IPHOHMKD_02493 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_02494 8.17e-203 - - - EGP - - - Major facilitator Superfamily
IPHOHMKD_02495 3.24e-221 ropB - - K - - - Helix-turn-helix XRE-family like proteins
IPHOHMKD_02496 1.44e-226 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
IPHOHMKD_02497 2.73e-148 - - - E ko:K03294 - ko00000 Amino acid permease
IPHOHMKD_02498 1.37e-141 - - - E ko:K03294 - ko00000 Amino acid permease
IPHOHMKD_02499 1.91e-295 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
IPHOHMKD_02500 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
IPHOHMKD_02501 2.85e-206 - - - I - - - alpha/beta hydrolase fold
IPHOHMKD_02502 6.11e-169 treR - - K ko:K03486 - ko00000,ko03000 UTRA
IPHOHMKD_02503 0.0 - - - - - - - -
IPHOHMKD_02504 2e-52 - - - S - - - Cytochrome B5
IPHOHMKD_02505 8.68e-118 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IPHOHMKD_02506 4.83e-278 - - - T - - - Diguanylate cyclase, GGDEF domain
IPHOHMKD_02507 8.07e-163 - - - T - - - Putative diguanylate phosphodiesterase
IPHOHMKD_02508 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IPHOHMKD_02509 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
IPHOHMKD_02510 1.56e-108 - - - - - - - -
IPHOHMKD_02511 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
IPHOHMKD_02512 1.53e-241 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IPHOHMKD_02513 1.26e-245 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPHOHMKD_02514 3.7e-30 - - - - - - - -
IPHOHMKD_02515 1.84e-134 - - - - - - - -
IPHOHMKD_02516 5.12e-212 - - - K - - - LysR substrate binding domain
IPHOHMKD_02517 4.34e-314 - - - P - - - Sodium:sulfate symporter transmembrane region
IPHOHMKD_02518 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
IPHOHMKD_02519 2.18e-245 - - - L - - - Transposase and inactivated derivatives, IS30 family
IPHOHMKD_02520 1.02e-106 tcaA - - S ko:K21463 - ko00000 response to antibiotic
IPHOHMKD_02521 1.07e-214 tcaA - - S ko:K21463 - ko00000 response to antibiotic
IPHOHMKD_02522 2.79e-184 - - - S - - - zinc-ribbon domain
IPHOHMKD_02524 4.29e-50 - - - - - - - -
IPHOHMKD_02525 2.78e-176 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
IPHOHMKD_02526 4.07e-232 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
IPHOHMKD_02527 0.0 - - - I - - - acetylesterase activity
IPHOHMKD_02528 2.43e-298 - - - M - - - Collagen binding domain
IPHOHMKD_02529 6.92e-206 yicL - - EG - - - EamA-like transporter family
IPHOHMKD_02530 3.03e-166 - - - E - - - lipolytic protein G-D-S-L family
IPHOHMKD_02531 3.39e-225 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
IPHOHMKD_02532 7.21e-145 - - - K - - - Transcriptional regulator C-terminal region
IPHOHMKD_02533 5.07e-62 - - - K - - - HxlR-like helix-turn-helix
IPHOHMKD_02534 1.25e-205 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
IPHOHMKD_02535 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
IPHOHMKD_02536 1.15e-115 - - - - - - - -
IPHOHMKD_02537 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
IPHOHMKD_02538 7.39e-121 - - - K - - - Transcriptional regulator, MarR family
IPHOHMKD_02539 5.85e-204 ccpB - - K - - - lacI family
IPHOHMKD_02540 9e-154 yceE - - S - - - haloacid dehalogenase-like hydrolase
IPHOHMKD_02541 8.08e-154 ydgI3 - - C - - - Nitroreductase family
IPHOHMKD_02542 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
IPHOHMKD_02543 3.87e-148 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IPHOHMKD_02544 2.48e-199 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IPHOHMKD_02545 5.98e-217 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
IPHOHMKD_02546 0.0 - - - - - - - -
IPHOHMKD_02547 4.71e-81 - - - - - - - -
IPHOHMKD_02548 9.55e-243 - - - S - - - Cell surface protein
IPHOHMKD_02549 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
IPHOHMKD_02550 5.06e-82 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
IPHOHMKD_02551 1.09e-42 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
IPHOHMKD_02552 2.78e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
IPHOHMKD_02553 5.21e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
IPHOHMKD_02554 1.88e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
IPHOHMKD_02555 9.73e-197 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
IPHOHMKD_02556 5.16e-270 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
IPHOHMKD_02558 1.15e-43 - - - - - - - -
IPHOHMKD_02559 6.9e-168 zmp3 - - O - - - Zinc-dependent metalloprotease
IPHOHMKD_02560 2.88e-106 gtcA3 - - S - - - GtrA-like protein
IPHOHMKD_02561 1.39e-157 - - - K - - - Helix-turn-helix XRE-family like proteins
IPHOHMKD_02562 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IPHOHMKD_02563 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
IPHOHMKD_02564 4.07e-61 - - - - - - - -
IPHOHMKD_02565 1.04e-149 - - - S - - - SNARE associated Golgi protein
IPHOHMKD_02566 8.58e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
IPHOHMKD_02567 7.89e-124 - - - P - - - Cadmium resistance transporter
IPHOHMKD_02568 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_02569 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
IPHOHMKD_02570 3.84e-144 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
IPHOHMKD_02571 2.03e-84 - - - - - - - -
IPHOHMKD_02572 1.93e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
IPHOHMKD_02573 2.45e-73 - - - - - - - -
IPHOHMKD_02574 1.24e-194 - - - K - - - Helix-turn-helix domain
IPHOHMKD_02575 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IPHOHMKD_02576 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
IPHOHMKD_02577 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPHOHMKD_02578 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IPHOHMKD_02579 3.18e-237 - - - GM - - - Male sterility protein
IPHOHMKD_02580 4.4e-101 - - - K - - - helix_turn_helix, mercury resistance
IPHOHMKD_02581 7.92e-94 - - - M - - - LysM domain
IPHOHMKD_02582 3.03e-130 - - - M - - - Lysin motif
IPHOHMKD_02583 1.4e-138 - - - S - - - SdpI/YhfL protein family
IPHOHMKD_02584 1.58e-72 nudA - - S - - - ASCH
IPHOHMKD_02585 5.76e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IPHOHMKD_02586 5.07e-120 - - - - - - - -
IPHOHMKD_02587 1.35e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
IPHOHMKD_02588 3.55e-281 - - - T - - - diguanylate cyclase
IPHOHMKD_02589 7.43e-97 - - - S - - - Psort location Cytoplasmic, score
IPHOHMKD_02590 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
IPHOHMKD_02591 2.31e-277 - - - - - - - -
IPHOHMKD_02592 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IPHOHMKD_02593 6.72e-23 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IPHOHMKD_02594 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_02595 1.65e-21 - - - - - - - -
IPHOHMKD_02596 3.23e-290 amd - - E - - - Peptidase family M20/M25/M40
IPHOHMKD_02597 2.96e-209 yhxD - - IQ - - - KR domain
IPHOHMKD_02599 1.97e-92 - - - - - - - -
IPHOHMKD_02600 4.1e-184 - - - K - - - Helix-turn-helix XRE-family like proteins
IPHOHMKD_02601 0.0 - - - E - - - Amino Acid
IPHOHMKD_02602 4.8e-86 lysM - - M - - - LysM domain
IPHOHMKD_02603 4.2e-286 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
IPHOHMKD_02604 1.6e-270 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
IPHOHMKD_02605 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
IPHOHMKD_02606 2.04e-56 - - - S - - - Cupredoxin-like domain
IPHOHMKD_02607 1.36e-84 - - - S - - - Cupredoxin-like domain
IPHOHMKD_02608 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IPHOHMKD_02609 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_02610 3.13e-99 - - - L - - - Transposase DDE domain
IPHOHMKD_02611 8.42e-215 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IPHOHMKD_02612 2.81e-181 - - - K - - - Helix-turn-helix domain
IPHOHMKD_02613 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
IPHOHMKD_02614 8.82e-102 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IPHOHMKD_02615 1.32e-173 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IPHOHMKD_02616 0.0 - - - - - - - -
IPHOHMKD_02617 2.69e-99 - - - - - - - -
IPHOHMKD_02618 2.85e-243 - - - S - - - Cell surface protein
IPHOHMKD_02619 6.02e-137 - - - S - - - WxL domain surface cell wall-binding
IPHOHMKD_02620 7.15e-230 - - - C - - - Alcohol dehydrogenase GroES-like domain
IPHOHMKD_02621 1.27e-90 - - - S - - - Iron-sulphur cluster biosynthesis
IPHOHMKD_02622 5.58e-36 - - - S - - - GyrI-like small molecule binding domain
IPHOHMKD_02623 7.07e-96 - - - S - - - GyrI-like small molecule binding domain
IPHOHMKD_02624 3.07e-241 ynjC - - S - - - Cell surface protein
IPHOHMKD_02625 4.48e-130 - - - S - - - WxL domain surface cell wall-binding
IPHOHMKD_02626 1.47e-83 - - - - - - - -
IPHOHMKD_02627 1.28e-195 - - - NU - - - Mycoplasma protein of unknown function, DUF285
IPHOHMKD_02628 1.68e-156 - - - - - - - -
IPHOHMKD_02629 2.91e-147 - - - S - - - Haloacid dehalogenase-like hydrolase
IPHOHMKD_02630 9.02e-76 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
IPHOHMKD_02631 2.69e-156 ORF00048 - - - - - - -
IPHOHMKD_02632 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
IPHOHMKD_02633 1.17e-268 - - - EGP - - - Major Facilitator
IPHOHMKD_02634 7.81e-148 - - - M - - - ErfK YbiS YcfS YnhG
IPHOHMKD_02635 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IPHOHMKD_02636 4.63e-173 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
IPHOHMKD_02637 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IPHOHMKD_02638 3.13e-99 - - - L - - - Transposase DDE domain
IPHOHMKD_02639 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_02640 1.59e-130 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_02641 1.26e-214 - - - GM - - - NmrA-like family
IPHOHMKD_02642 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IPHOHMKD_02643 0.0 - - - M - - - Glycosyl hydrolases family 25
IPHOHMKD_02644 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
IPHOHMKD_02645 7.34e-83 - - - K - - - HxlR-like helix-turn-helix
IPHOHMKD_02646 1.52e-149 - - - S - - - KR domain
IPHOHMKD_02647 4.57e-123 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_02648 3.47e-244 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
IPHOHMKD_02649 1.27e-129 - - - S - - - Protein of unknown function (DUF1211)
IPHOHMKD_02650 1.97e-229 ydhF - - S - - - Aldo keto reductase
IPHOHMKD_02653 0.0 yfjF - - U - - - Sugar (and other) transporter
IPHOHMKD_02654 7.57e-141 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_02655 1.66e-217 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IPHOHMKD_02656 6.37e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IPHOHMKD_02657 1.05e-227 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPHOHMKD_02658 1.88e-79 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPHOHMKD_02659 1.65e-125 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPHOHMKD_02660 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_02661 1.3e-208 - - - GM - - - NmrA-like family
IPHOHMKD_02662 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IPHOHMKD_02663 4.01e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
IPHOHMKD_02664 1.83e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IPHOHMKD_02665 4.51e-84 - - - K - - - helix_turn_helix, mercury resistance
IPHOHMKD_02666 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
IPHOHMKD_02667 1.94e-230 - - - S - - - Bacterial protein of unknown function (DUF916)
IPHOHMKD_02668 5.78e-50 - - - S - - - WxL domain surface cell wall-binding
IPHOHMKD_02669 1.13e-261 - - - NU - - - Mycoplasma protein of unknown function, DUF285
IPHOHMKD_02670 6.88e-152 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_02671 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IPHOHMKD_02672 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
IPHOHMKD_02673 4.54e-202 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
IPHOHMKD_02674 2.24e-207 - - - K - - - LysR substrate binding domain
IPHOHMKD_02675 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
IPHOHMKD_02676 0.0 - - - S - - - MucBP domain
IPHOHMKD_02677 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IPHOHMKD_02678 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
IPHOHMKD_02679 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IPHOHMKD_02680 9.2e-317 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPHOHMKD_02681 2.09e-85 - - - - - - - -
IPHOHMKD_02682 5.15e-16 - - - - - - - -
IPHOHMKD_02683 5.61e-54 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
IPHOHMKD_02684 3.41e-31 - - - K - - - helix_turn_helix, mercury resistance
IPHOHMKD_02685 5.98e-85 - - - S - - - Protein of unknown function (DUF1093)
IPHOHMKD_02686 1.83e-281 - - - S - - - Membrane
IPHOHMKD_02687 1.04e-59 - - - S - - - Protein of unknown function (DUF3781)
IPHOHMKD_02688 1.31e-139 yoaZ - - S - - - intracellular protease amidase
IPHOHMKD_02689 1.4e-57 - - - K - - - HxlR-like helix-turn-helix
IPHOHMKD_02690 8.95e-53 - - - C - - - Alcohol dehydrogenase GroES-like domain
IPHOHMKD_02691 9.72e-121 - - - C - - - Alcohol dehydrogenase GroES-like domain
IPHOHMKD_02692 2.61e-259 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
IPHOHMKD_02693 6.27e-104 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IPHOHMKD_02694 5.04e-92 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IPHOHMKD_02695 1.34e-153 yciB - - M - - - ErfK YbiS YcfS YnhG
IPHOHMKD_02696 8.09e-142 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
IPHOHMKD_02697 4.73e-140 - - - GM - - - NAD(P)H-binding
IPHOHMKD_02698 5.35e-102 - - - GM - - - SnoaL-like domain
IPHOHMKD_02699 0.0 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
IPHOHMKD_02700 1.9e-26 - - - S - - - Domain of unknown function (DUF4440)
IPHOHMKD_02701 2.26e-135 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_02702 3.87e-44 - - - L ko:K07483 - ko00000 transposase activity
IPHOHMKD_02704 6.79e-53 - - - - - - - -
IPHOHMKD_02705 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IPHOHMKD_02706 3.77e-232 ydbI - - K - - - AI-2E family transporter
IPHOHMKD_02707 2.66e-270 xylR - - GK - - - ROK family
IPHOHMKD_02708 5.21e-151 - - - - - - - -
IPHOHMKD_02709 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
IPHOHMKD_02710 1.84e-207 - - - - - - - -
IPHOHMKD_02711 1.66e-259 pkn2 - - KLT - - - Protein tyrosine kinase
IPHOHMKD_02712 5.03e-37 - - - S - - - Protein of unknown function (DUF4064)
IPHOHMKD_02713 3.51e-125 - - - S - - - Domain of unknown function (DUF4352)
IPHOHMKD_02714 5.61e-98 - - - S - - - Psort location Cytoplasmic, score
IPHOHMKD_02715 5.01e-71 - - - - - - - -
IPHOHMKD_02716 3.37e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
IPHOHMKD_02717 5.93e-73 - - - S - - - branched-chain amino acid
IPHOHMKD_02718 1.19e-166 - - - E - - - branched-chain amino acid
IPHOHMKD_02719 2.27e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
IPHOHMKD_02720 2.66e-305 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IPHOHMKD_02721 5.61e-273 hpk31 - - T - - - Histidine kinase
IPHOHMKD_02722 1.14e-159 vanR - - K - - - response regulator
IPHOHMKD_02723 5.65e-160 - - - S - - - Protein of unknown function (DUF1275)
IPHOHMKD_02724 3.3e-208 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IPHOHMKD_02725 1e-269 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IPHOHMKD_02726 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
IPHOHMKD_02727 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IPHOHMKD_02728 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
IPHOHMKD_02729 6.14e-202 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IPHOHMKD_02730 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
IPHOHMKD_02731 7.39e-192 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IPHOHMKD_02732 1.81e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
IPHOHMKD_02733 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
IPHOHMKD_02734 5.43e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
IPHOHMKD_02735 3.36e-216 - - - K - - - LysR substrate binding domain
IPHOHMKD_02736 2.07e-302 - - - EK - - - Aminotransferase, class I
IPHOHMKD_02737 2.13e-167 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
IPHOHMKD_02738 7.06e-157 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IPHOHMKD_02739 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_02740 2.08e-160 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
IPHOHMKD_02741 1.07e-127 - - - KT - - - response to antibiotic
IPHOHMKD_02742 3.08e-67 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
IPHOHMKD_02743 4.54e-128 - - - S - - - Protein of unknown function (DUF1700)
IPHOHMKD_02744 1.13e-200 - - - S - - - Putative adhesin
IPHOHMKD_02745 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IPHOHMKD_02746 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
IPHOHMKD_02747 2.6e-233 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
IPHOHMKD_02748 7.52e-263 - - - S - - - DUF218 domain
IPHOHMKD_02749 9.95e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
IPHOHMKD_02750 1.76e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IPHOHMKD_02751 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPHOHMKD_02752 6.26e-101 - - - - - - - -
IPHOHMKD_02753 2.69e-194 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
IPHOHMKD_02754 3.54e-190 - - - S - - - haloacid dehalogenase-like hydrolase
IPHOHMKD_02755 1.29e-115 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
IPHOHMKD_02756 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
IPHOHMKD_02757 6.69e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
IPHOHMKD_02758 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
IPHOHMKD_02759 5.55e-22 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
IPHOHMKD_02760 2.28e-103 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IPHOHMKD_02761 4.08e-101 - - - K - - - MerR family regulatory protein
IPHOHMKD_02762 7.22e-198 - - - GM - - - NmrA-like family
IPHOHMKD_02763 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IPHOHMKD_02764 5.08e-164 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
IPHOHMKD_02766 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
IPHOHMKD_02767 3.43e-303 - - - S - - - module of peptide synthetase
IPHOHMKD_02768 1.78e-139 - - - - - - - -
IPHOHMKD_02769 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
IPHOHMKD_02770 1.28e-77 - - - S - - - Enterocin A Immunity
IPHOHMKD_02771 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
IPHOHMKD_02772 7.93e-217 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
IPHOHMKD_02773 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
IPHOHMKD_02774 3.97e-82 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
IPHOHMKD_02775 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
IPHOHMKD_02776 3.84e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
IPHOHMKD_02777 1.03e-34 - - - - - - - -
IPHOHMKD_02778 2.45e-151 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
IPHOHMKD_02779 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
IPHOHMKD_02780 8.52e-212 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
IPHOHMKD_02781 7.77e-234 - - - D ko:K06889 - ko00000 Alpha beta
IPHOHMKD_02782 1.17e-250 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
IPHOHMKD_02783 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
IPHOHMKD_02784 2.49e-73 - - - S - - - Enterocin A Immunity
IPHOHMKD_02785 7.41e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IPHOHMKD_02786 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IPHOHMKD_02787 4.17e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IPHOHMKD_02788 1.02e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
IPHOHMKD_02789 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPHOHMKD_02791 7.97e-108 - - - - - - - -
IPHOHMKD_02792 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
IPHOHMKD_02794 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
IPHOHMKD_02795 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPHOHMKD_02796 1.54e-228 ydbI - - K - - - AI-2E family transporter
IPHOHMKD_02797 6.83e-276 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
IPHOHMKD_02798 1.15e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
IPHOHMKD_02799 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
IPHOHMKD_02800 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
IPHOHMKD_02801 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
IPHOHMKD_02802 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
IPHOHMKD_02803 8.03e-28 - - - - - - - -
IPHOHMKD_02804 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
IPHOHMKD_02805 2.28e-270 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
IPHOHMKD_02806 8.45e-129 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
IPHOHMKD_02807 2.07e-314 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
IPHOHMKD_02808 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
IPHOHMKD_02809 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IPHOHMKD_02810 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IPHOHMKD_02811 4.26e-109 cvpA - - S - - - Colicin V production protein
IPHOHMKD_02812 4.58e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IPHOHMKD_02813 1.15e-315 - - - EGP - - - Major Facilitator
IPHOHMKD_02815 4.54e-54 - - - - - - - -
IPHOHMKD_02816 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
IPHOHMKD_02817 3.74e-125 - - - V - - - VanZ like family
IPHOHMKD_02818 5.36e-249 - - - V - - - Beta-lactamase
IPHOHMKD_02819 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
IPHOHMKD_02820 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IPHOHMKD_02821 8.93e-71 - - - S - - - Pfam:DUF59
IPHOHMKD_02822 6.07e-223 ydhF - - S - - - Aldo keto reductase
IPHOHMKD_02823 2.42e-127 - - - FG - - - HIT domain
IPHOHMKD_02824 1.03e-50 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
IPHOHMKD_02825 3.53e-100 - - - - - - - -
IPHOHMKD_02826 8.79e-156 - - - E - - - GDSL-like Lipase/Acylhydrolase family
IPHOHMKD_02827 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
IPHOHMKD_02828 0.0 cadA - - P - - - P-type ATPase
IPHOHMKD_02830 2.32e-160 - - - S - - - YjbR
IPHOHMKD_02831 1.07e-281 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
IPHOHMKD_02832 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IPHOHMKD_02833 1.42e-252 glmS2 - - M - - - SIS domain
IPHOHMKD_02834 5.92e-35 - - - S - - - Belongs to the LOG family
IPHOHMKD_02835 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
IPHOHMKD_02836 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
IPHOHMKD_02837 2.65e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
IPHOHMKD_02838 1.65e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
IPHOHMKD_02839 1.36e-209 - - - GM - - - NmrA-like family
IPHOHMKD_02840 7.45e-87 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
IPHOHMKD_02841 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
IPHOHMKD_02842 3.46e-87 yeaO - - S - - - Protein of unknown function, DUF488
IPHOHMKD_02843 1.7e-70 - - - - - - - -
IPHOHMKD_02844 4.98e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
IPHOHMKD_02845 2.11e-82 - - - - - - - -
IPHOHMKD_02846 1.36e-112 - - - - - - - -
IPHOHMKD_02847 3.22e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IPHOHMKD_02848 2.27e-74 - - - - - - - -
IPHOHMKD_02849 4.79e-21 - - - - - - - -
IPHOHMKD_02850 3.57e-150 - - - GM - - - NmrA-like family
IPHOHMKD_02851 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
IPHOHMKD_02852 1.63e-203 - - - EG - - - EamA-like transporter family
IPHOHMKD_02853 2.66e-155 - - - S - - - membrane
IPHOHMKD_02854 1.47e-144 - - - S - - - VIT family
IPHOHMKD_02855 4.38e-243 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
IPHOHMKD_02856 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
IPHOHMKD_02857 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
IPHOHMKD_02858 1.22e-53 - - - - - - - -
IPHOHMKD_02859 8.43e-97 - - - S - - - COG NOG18757 non supervised orthologous group
IPHOHMKD_02860 2.52e-314 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
IPHOHMKD_02861 2.42e-33 - - - - - - - -
IPHOHMKD_02862 2.55e-65 - - - - - - - -
IPHOHMKD_02863 2.51e-84 - - - S - - - Protein of unknown function (DUF1398)
IPHOHMKD_02864 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
IPHOHMKD_02865 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
IPHOHMKD_02866 3.83e-229 ybcH - - D ko:K06889 - ko00000 Alpha beta
IPHOHMKD_02867 7.13e-100 - - - K - - - Domain of unknown function (DUF1836)
IPHOHMKD_02868 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
IPHOHMKD_02869 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
IPHOHMKD_02870 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IPHOHMKD_02871 2.3e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
IPHOHMKD_02872 1.36e-209 yvgN - - C - - - Aldo keto reductase
IPHOHMKD_02873 2.57e-171 - - - S - - - Putative threonine/serine exporter
IPHOHMKD_02874 1.7e-101 - - - S - - - Threonine/Serine exporter, ThrE
IPHOHMKD_02875 1.5e-56 - - - S - - - Protein of unknown function (DUF1093)
IPHOHMKD_02876 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IPHOHMKD_02877 6.94e-117 ymdB - - S - - - Macro domain protein
IPHOHMKD_02878 5.31e-123 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
IPHOHMKD_02879 1.58e-66 - - - - - - - -
IPHOHMKD_02880 2.81e-211 - - - S - - - Protein of unknown function (DUF1002)
IPHOHMKD_02881 0.0 - - - - - - - -
IPHOHMKD_02882 6.48e-244 - - - S - - - Bacterial protein of unknown function (DUF916)
IPHOHMKD_02883 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
IPHOHMKD_02884 1.51e-175 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
IPHOHMKD_02885 4.25e-198 - - - L ko:K07482 - ko00000 Integrase core domain
IPHOHMKD_02886 5.33e-114 - - - K - - - Winged helix DNA-binding domain
IPHOHMKD_02887 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
IPHOHMKD_02888 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
IPHOHMKD_02889 4.45e-38 - - - - - - - -
IPHOHMKD_02890 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
IPHOHMKD_02891 7.55e-96 - - - M - - - PFAM NLP P60 protein
IPHOHMKD_02892 6.18e-71 - - - - - - - -
IPHOHMKD_02893 9.96e-82 - - - - - - - -
IPHOHMKD_02896 6.57e-84 - - - V - - - VanZ like family
IPHOHMKD_02898 1.17e-15 - - - K - - - Cro/C1-type HTH DNA-binding domain
IPHOHMKD_02899 2.97e-137 - - - - - - - -
IPHOHMKD_02900 2.56e-70 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
IPHOHMKD_02901 5.21e-153 - - - S ko:K07045 - ko00000 Amidohydrolase
IPHOHMKD_02902 5.14e-131 - - - K - - - transcriptional regulator
IPHOHMKD_02903 7.17e-232 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
IPHOHMKD_02904 4.16e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IPHOHMKD_02905 3.04e-165 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
IPHOHMKD_02906 1.98e-232 - - - E - - - GDSL-like Lipase/Acylhydrolase family
IPHOHMKD_02907 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
IPHOHMKD_02908 9.44e-183 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IPHOHMKD_02909 5.73e-73 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
IPHOHMKD_02910 1.96e-54 yrkD - - S - - - Metal-sensitive transcriptional repressor
IPHOHMKD_02911 1.01e-26 - - - - - - - -
IPHOHMKD_02912 3.51e-125 dpsB - - P - - - Belongs to the Dps family
IPHOHMKD_02913 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
IPHOHMKD_02914 2.59e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
IPHOHMKD_02915 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
IPHOHMKD_02916 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IPHOHMKD_02917 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
IPHOHMKD_02918 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
IPHOHMKD_02919 2.88e-220 - - - S - - - Cell surface protein
IPHOHMKD_02920 8.67e-160 - - - S - - - WxL domain surface cell wall-binding
IPHOHMKD_02921 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
IPHOHMKD_02922 7.83e-60 - - - - - - - -
IPHOHMKD_02923 1.72e-135 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
IPHOHMKD_02924 1.03e-65 - - - - - - - -
IPHOHMKD_02925 1.87e-316 - - - S - - - Putative metallopeptidase domain
IPHOHMKD_02926 1.35e-281 - - - S - - - associated with various cellular activities
IPHOHMKD_02927 1.95e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IPHOHMKD_02928 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
IPHOHMKD_02929 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IPHOHMKD_02930 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
IPHOHMKD_02931 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
IPHOHMKD_02932 1.11e-240 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IPHOHMKD_02933 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
IPHOHMKD_02934 1.23e-294 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
IPHOHMKD_02935 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
IPHOHMKD_02936 1.02e-297 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
IPHOHMKD_02937 3.71e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
IPHOHMKD_02938 3.9e-143 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
IPHOHMKD_02939 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
IPHOHMKD_02940 6.88e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IPHOHMKD_02941 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IPHOHMKD_02942 5.14e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IPHOHMKD_02943 7.83e-285 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IPHOHMKD_02944 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
IPHOHMKD_02945 9.11e-236 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
IPHOHMKD_02946 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
IPHOHMKD_02947 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
IPHOHMKD_02948 1.43e-251 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
IPHOHMKD_02949 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IPHOHMKD_02950 1.22e-246 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
IPHOHMKD_02951 2.02e-85 - - - S - - - pyridoxamine 5-phosphate
IPHOHMKD_02952 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
IPHOHMKD_02953 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IPHOHMKD_02954 2.2e-173 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IPHOHMKD_02955 7.89e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPHOHMKD_02956 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
IPHOHMKD_02957 1.4e-282 - - - EGP - - - Major Facilitator Superfamily
IPHOHMKD_02958 1.71e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPHOHMKD_02959 8.13e-206 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPHOHMKD_02960 1.64e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
IPHOHMKD_02961 5.56e-212 - - - G - - - Xylose isomerase-like TIM barrel
IPHOHMKD_02962 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
IPHOHMKD_02963 9.16e-262 - - - EGP - - - Major Facilitator Superfamily
IPHOHMKD_02964 2.09e-83 - - - - - - - -
IPHOHMKD_02965 2.16e-199 estA - - S - - - Putative esterase
IPHOHMKD_02966 3.15e-173 - - - K - - - UTRA domain
IPHOHMKD_02967 1.87e-316 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPHOHMKD_02968 9.37e-207 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IPHOHMKD_02969 1.69e-202 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
IPHOHMKD_02970 2.26e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
IPHOHMKD_02971 8.74e-151 - - - K - - - helix_turn_helix, arabinose operon control protein
IPHOHMKD_02972 3.41e-283 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IPHOHMKD_02973 0.0 - - - C - - - FAD binding domain
IPHOHMKD_02974 6.22e-113 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
IPHOHMKD_02975 1.09e-312 - 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Alpha mannosidase, middle domain
IPHOHMKD_02976 2.14e-291 - - - GT - - - Phosphotransferase System
IPHOHMKD_02977 1.55e-65 - - - K - - - Helix-turn-helix domain, rpiR family
IPHOHMKD_02978 5.36e-90 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IPHOHMKD_02979 1.52e-264 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IPHOHMKD_02980 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IPHOHMKD_02981 1.85e-152 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
IPHOHMKD_02982 0.0 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IPHOHMKD_02983 2.24e-284 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
IPHOHMKD_02984 0.0 pts31BC - - G ko:K11202,ko:K11203 - ko00000,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
IPHOHMKD_02985 1.17e-96 - - - G ko:K11201 - ko00000,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IPHOHMKD_02986 1.48e-103 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IPHOHMKD_02987 2.29e-190 yleF - - K - - - Helix-turn-helix domain, rpiR family
IPHOHMKD_02988 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IPHOHMKD_02989 8.71e-202 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IPHOHMKD_02990 9.33e-252 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
IPHOHMKD_02991 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IPHOHMKD_02992 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IPHOHMKD_02993 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IPHOHMKD_02994 1.3e-203 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
IPHOHMKD_02995 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
IPHOHMKD_02996 2.66e-222 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
IPHOHMKD_02997 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
IPHOHMKD_02998 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
IPHOHMKD_03000 1.91e-235 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IPHOHMKD_03001 4.28e-185 yxeH - - S - - - hydrolase
IPHOHMKD_03002 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IPHOHMKD_03003 1.02e-147 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IPHOHMKD_03004 4.56e-303 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
IPHOHMKD_03005 7.29e-61 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
IPHOHMKD_03006 1.58e-101 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IPHOHMKD_03007 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IPHOHMKD_03008 9.14e-146 gph3 - - S - - - Haloacid dehalogenase-like hydrolase
IPHOHMKD_03009 1.51e-246 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
IPHOHMKD_03010 6.87e-295 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
IPHOHMKD_03011 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
IPHOHMKD_03012 4.66e-105 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IPHOHMKD_03013 1.83e-146 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
IPHOHMKD_03014 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
IPHOHMKD_03015 3.76e-180 - - - K - - - Helix-turn-helix domain, rpiR family
IPHOHMKD_03016 6.47e-95 - - - S - - - Protein of unknown function (DUF1694)
IPHOHMKD_03017 7.3e-210 - - - I - - - alpha/beta hydrolase fold
IPHOHMKD_03018 1.93e-205 - - - I - - - alpha/beta hydrolase fold
IPHOHMKD_03019 0.0 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPHOHMKD_03020 1.63e-262 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IPHOHMKD_03021 3.83e-174 - - - G - - - Xylose isomerase domain protein TIM barrel
IPHOHMKD_03022 2.93e-200 nanK - - GK - - - ROK family
IPHOHMKD_03023 1.86e-210 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
IPHOHMKD_03024 2.13e-159 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IPHOHMKD_03025 5.6e-292 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
IPHOHMKD_03026 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
IPHOHMKD_03027 2.1e-116 - - - T - - - ECF transporter, substrate-specific component
IPHOHMKD_03028 1.06e-16 - - - - - - - -
IPHOHMKD_03029 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
IPHOHMKD_03030 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
IPHOHMKD_03031 1.32e-101 nrp - - K ko:K16509 - ko00000 ArsC family
IPHOHMKD_03032 7.42e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
IPHOHMKD_03033 3.78e-212 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IPHOHMKD_03034 9.62e-19 - - - - - - - -
IPHOHMKD_03035 1.51e-85 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
IPHOHMKD_03036 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
IPHOHMKD_03038 1.33e-254 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IPHOHMKD_03039 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IPHOHMKD_03040 5.03e-95 - - - K - - - Transcriptional regulator
IPHOHMKD_03041 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IPHOHMKD_03042 6.71e-93 yueI - - S - - - Protein of unknown function (DUF1694)
IPHOHMKD_03043 2.92e-162 - - - S - - - Membrane
IPHOHMKD_03044 7.58e-210 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
IPHOHMKD_03045 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
IPHOHMKD_03046 1.72e-73 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
IPHOHMKD_03047 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IPHOHMKD_03048 6.57e-311 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
IPHOHMKD_03049 1.44e-230 rhaR - - K - - - helix_turn_helix, arabinose operon control protein
IPHOHMKD_03050 7.4e-180 - - - K - - - DeoR C terminal sensor domain
IPHOHMKD_03051 3.71e-105 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IPHOHMKD_03052 7.08e-68 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
IPHOHMKD_03053 0.0 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
IPHOHMKD_03055 7.16e-173 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
IPHOHMKD_03056 0.0 - - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IPHOHMKD_03057 8.29e-252 iolG2 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IPHOHMKD_03058 2.4e-258 iolG 1.1.1.18, 1.1.1.369 - C ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IPHOHMKD_03059 2.79e-225 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IPHOHMKD_03060 5.39e-251 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IPHOHMKD_03061 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IPHOHMKD_03062 1.53e-245 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IPHOHMKD_03063 7.45e-108 - - - S - - - Haem-degrading
IPHOHMKD_03064 1.6e-220 - - - C - - - Alcohol dehydrogenase GroES-like domain
IPHOHMKD_03065 1.44e-228 - - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
IPHOHMKD_03066 7.14e-44 - - - L ko:K07482 - ko00000 Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IPHOHMKD_03067 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
IPHOHMKD_03068 8.36e-233 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
IPHOHMKD_03069 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
IPHOHMKD_03070 1.36e-112 srlM1 - - K - - - Glucitol operon activator protein (GutM)
IPHOHMKD_03071 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
IPHOHMKD_03072 1.56e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
IPHOHMKD_03073 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
IPHOHMKD_03074 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IPHOHMKD_03075 3.71e-208 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPHOHMKD_03076 1.88e-240 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IPHOHMKD_03077 3.36e-06 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
IPHOHMKD_03078 1.08e-08 - - - - - - - -
IPHOHMKD_03079 2.2e-26 - - - - - - - -
IPHOHMKD_03080 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
IPHOHMKD_03081 2.51e-103 - - - T - - - Universal stress protein family
IPHOHMKD_03082 7.43e-130 padR - - K - - - Virulence activator alpha C-term
IPHOHMKD_03083 2.14e-132 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
IPHOHMKD_03084 1.13e-182 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
IPHOHMKD_03085 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
IPHOHMKD_03086 3.3e-202 degV1 - - S - - - DegV family
IPHOHMKD_03087 2.89e-80 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
IPHOHMKD_03088 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
IPHOHMKD_03090 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IPHOHMKD_03091 0.0 - - - - - - - -
IPHOHMKD_03093 3.68e-210 - - - S - - - Bacterial protein of unknown function (DUF916)
IPHOHMKD_03094 1.31e-143 - - - S - - - Cell surface protein
IPHOHMKD_03095 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IPHOHMKD_03096 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IPHOHMKD_03097 2.14e-155 jag - - S ko:K06346 - ko00000 R3H domain protein
IPHOHMKD_03098 3.75e-305 - - - Q - - - Imidazolonepropionase and related amidohydrolases
IPHOHMKD_03099 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
IPHOHMKD_03100 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IPHOHMKD_03101 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IPHOHMKD_03102 1.54e-19 - - - S - - - maturation of SSU-rRNA
IPHOHMKD_03103 5.61e-47 yddH - - M - - - Lysozyme-like
IPHOHMKD_03107 1.16e-47 - - - - - - - -
IPHOHMKD_03109 2.39e-71 - - - S ko:K12063 - ko00000,ko02044 helicase activity
IPHOHMKD_03112 5.61e-27 - - - S - - - ABC-2 family transporter protein
IPHOHMKD_03113 3.49e-66 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IPHOHMKD_03120 5.92e-222 - - - S - - - AAA-like domain
IPHOHMKD_03123 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
IPHOHMKD_03124 4.68e-71 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_03125 5.98e-212 - - - P - - - CorA-like Mg2+ transporter protein
IPHOHMKD_03126 3.03e-49 - - - K - - - sequence-specific DNA binding
IPHOHMKD_03127 2.08e-60 - - - S - - - Phage derived protein Gp49-like (DUF891)
IPHOHMKD_03128 7.6e-139 - - - L - - - Integrase
IPHOHMKD_03129 1.15e-59 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
IPHOHMKD_03130 7.43e-77 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
IPHOHMKD_03131 1.09e-289 - - - G - - - Polysaccharide deacetylase
IPHOHMKD_03132 1.76e-32 - - - - - - - -
IPHOHMKD_03133 6.1e-205 - - - L - - - Initiator Replication protein
IPHOHMKD_03134 1.24e-39 - - - - - - - -
IPHOHMKD_03135 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
IPHOHMKD_03136 3.13e-99 - - - L - - - Transposase DDE domain
IPHOHMKD_03137 1.45e-103 - - - L - - - Phage integrase family
IPHOHMKD_03138 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
IPHOHMKD_03139 1.77e-56 - - - - - - - -
IPHOHMKD_03140 1.01e-58 repA - - S - - - Replication initiator protein A
IPHOHMKD_03141 1.18e-232 - - - U - - - Relaxase/Mobilisation nuclease domain
IPHOHMKD_03142 1.84e-69 - - - S - - - Bacterial mobilisation protein (MobC)
IPHOHMKD_03143 4.68e-243 - - - L - - - Psort location Cytoplasmic, score
IPHOHMKD_03144 6.73e-132 cadD - - P - - - Cadmium resistance transporter
IPHOHMKD_03145 1.33e-79 - - - K - - - Transcriptional regulator
IPHOHMKD_03146 2.42e-281 B4168_4126 - - L ko:K07493 - ko00000 Transposase
IPHOHMKD_03147 5.41e-89 - - - C - - - lyase activity
IPHOHMKD_03148 9.99e-19 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
IPHOHMKD_03149 3.46e-128 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
IPHOHMKD_03150 3.79e-250 - - - O - - - Heat shock 70 kDa protein
IPHOHMKD_03151 4.76e-56 - - - - - - - -
IPHOHMKD_03152 1.15e-57 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
IPHOHMKD_03153 1.11e-37 - - - - - - - -
IPHOHMKD_03154 5.98e-55 - - - - - - - -
IPHOHMKD_03155 1.39e-36 - - - - - - - -
IPHOHMKD_03156 0.0 traA - - L - - - MobA MobL family protein
IPHOHMKD_03157 9.45e-302 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IPHOHMKD_03158 6.96e-145 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IPHOHMKD_03159 7.81e-46 - - - - - - - -
IPHOHMKD_03160 2.08e-111 - - - - - - - -
IPHOHMKD_03161 3.77e-139 - - - L - - - Integrase
IPHOHMKD_03162 2.96e-55 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
IPHOHMKD_03163 9.45e-67 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
IPHOHMKD_03164 2.34e-130 - - - - - - - -
IPHOHMKD_03165 7.97e-127 yhdJ 2.1.1.72 - L ko:K00571,ko:K07319 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
IPHOHMKD_03166 7.5e-68 - - - - - - - -
IPHOHMKD_03167 1.09e-196 - - - L - - - Initiator Replication protein
IPHOHMKD_03168 1.73e-81 - - - - - - - -
IPHOHMKD_03169 6.14e-133 - - - L - - - Phage integrase family
IPHOHMKD_03170 3.12e-186 - - - - - - - -
IPHOHMKD_03171 1.39e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IPHOHMKD_03172 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
IPHOHMKD_03174 1.39e-110 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IPHOHMKD_03175 6.66e-115 - - - - - - - -
IPHOHMKD_03176 2.29e-225 - - - L - - - Initiator Replication protein
IPHOHMKD_03177 3.67e-41 - - - - - - - -
IPHOHMKD_03178 1.87e-139 - - - L - - - Integrase
IPHOHMKD_03179 4.17e-55 - - - K - - - prlF antitoxin for toxin YhaV_toxin
IPHOHMKD_03180 1.03e-77 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
IPHOHMKD_03181 3.81e-35 - - - - - - - -
IPHOHMKD_03183 9.24e-140 - - - L - - - Integrase
IPHOHMKD_03184 2.22e-59 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin
IPHOHMKD_03185 3.2e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
IPHOHMKD_03187 4.44e-105 - - - L - - - Initiator Replication protein
IPHOHMKD_03189 7.08e-42 - - - S - - - Bacterial mobilisation protein (MobC)
IPHOHMKD_03190 2.64e-211 - - - U - - - Relaxase/Mobilisation nuclease domain

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)