ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
IIEKHHNG_00017 4.79e-259 - - - C - - - Na+/H+ antiporter family
IIEKHHNG_00018 1.57e-172 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
IIEKHHNG_00019 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IIEKHHNG_00020 0.0 ygaK - - C - - - Berberine and berberine like
IIEKHHNG_00022 9.91e-288 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
IIEKHHNG_00023 1.17e-178 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IIEKHHNG_00024 8.8e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIEKHHNG_00025 3.14e-169 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IIEKHHNG_00026 3.29e-168 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IIEKHHNG_00027 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IIEKHHNG_00028 4.68e-234 - - - S ko:K07045 - ko00000 Amidohydrolase
IIEKHHNG_00029 1.5e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IIEKHHNG_00030 7.12e-229 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
IIEKHHNG_00031 8.27e-186 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IIEKHHNG_00032 1.17e-270 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
IIEKHHNG_00033 3.39e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IIEKHHNG_00034 1.29e-106 ygaO - - - - - - -
IIEKHHNG_00035 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_00037 7.82e-147 yhzB - - S - - - B3/4 domain
IIEKHHNG_00038 2.08e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IIEKHHNG_00039 2.08e-225 yhbB - - S - - - Putative amidase domain
IIEKHHNG_00040 4.84e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IIEKHHNG_00041 4.63e-139 yhbD - - K - - - Protein of unknown function (DUF4004)
IIEKHHNG_00042 3.99e-85 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IIEKHHNG_00043 2.02e-94 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IIEKHHNG_00044 1.23e-07 - - - - - - - -
IIEKHHNG_00045 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
IIEKHHNG_00046 5.45e-279 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
IIEKHHNG_00047 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
IIEKHHNG_00048 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
IIEKHHNG_00049 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
IIEKHHNG_00050 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
IIEKHHNG_00051 1.41e-72 yhcC - - - - - - -
IIEKHHNG_00052 1.6e-89 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_00053 2.23e-209 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IIEKHHNG_00054 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
IIEKHHNG_00055 5.86e-190 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
IIEKHHNG_00056 1.01e-234 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
IIEKHHNG_00057 4.31e-292 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIEKHHNG_00058 1.74e-72 yhcM - - - - - - -
IIEKHHNG_00059 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IIEKHHNG_00060 1.85e-204 yhcP - - - - - - -
IIEKHHNG_00061 4.45e-151 yhcQ - - M - - - Spore coat protein
IIEKHHNG_00062 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IIEKHHNG_00063 1.3e-136 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
IIEKHHNG_00064 2.27e-216 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IIEKHHNG_00065 7.37e-90 yhcU - - S - - - Family of unknown function (DUF5365)
IIEKHHNG_00066 6.12e-91 yhcV - - S - - - COG0517 FOG CBS domain
IIEKHHNG_00067 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
IIEKHHNG_00068 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IIEKHHNG_00069 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IIEKHHNG_00070 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IIEKHHNG_00071 2.83e-199 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IIEKHHNG_00072 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IIEKHHNG_00073 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IIEKHHNG_00074 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
IIEKHHNG_00075 8.75e-262 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_00076 1.56e-143 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIEKHHNG_00077 9.77e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
IIEKHHNG_00078 1.16e-51 yhdB - - S - - - YhdB-like protein
IIEKHHNG_00079 2.94e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
IIEKHHNG_00080 1.04e-297 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IIEKHHNG_00081 3.79e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
IIEKHHNG_00082 0.0 ygxB - - M - - - Conserved TM helix
IIEKHHNG_00083 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
IIEKHHNG_00084 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
IIEKHHNG_00085 2.8e-171 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IIEKHHNG_00086 8.17e-209 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_00087 6.39e-259 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IIEKHHNG_00088 1.58e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIEKHHNG_00089 1.78e-316 yhdG - - E ko:K03294 - ko00000 amino acid
IIEKHHNG_00090 8.02e-265 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IIEKHHNG_00091 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
IIEKHHNG_00092 6.88e-257 yhdL - - S - - - Sigma factor regulator N-terminal
IIEKHHNG_00093 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IIEKHHNG_00094 9.21e-142 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IIEKHHNG_00095 2.28e-306 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IIEKHHNG_00096 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
IIEKHHNG_00097 4.05e-286 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IIEKHHNG_00098 9.1e-300 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IIEKHHNG_00099 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
IIEKHHNG_00100 2.9e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIEKHHNG_00101 4.97e-79 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIEKHHNG_00102 1.49e-164 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IIEKHHNG_00103 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
IIEKHHNG_00104 4.51e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
IIEKHHNG_00105 7.18e-181 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IIEKHHNG_00106 4.01e-200 nodB1 - - G - - - deacetylase
IIEKHHNG_00107 3.99e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IIEKHHNG_00108 1.43e-113 pksA - - K - - - Transcriptional regulator
IIEKHHNG_00109 3.12e-123 ymcC - - S - - - Membrane
IIEKHHNG_00110 2.49e-110 - - - T - - - universal stress protein
IIEKHHNG_00112 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IIEKHHNG_00113 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IIEKHHNG_00114 7.8e-142 yheG - - GM - - - NAD(P)H-binding
IIEKHHNG_00116 3.3e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
IIEKHHNG_00117 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
IIEKHHNG_00118 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
IIEKHHNG_00119 1.54e-272 yheC - - HJ - - - YheC/D like ATP-grasp
IIEKHHNG_00120 7.84e-264 yheB - - S - - - Belongs to the UPF0754 family
IIEKHHNG_00121 2.32e-70 yheA - - S - - - Belongs to the UPF0342 family
IIEKHHNG_00122 1.74e-258 yhaZ - - L - - - DNA alkylation repair enzyme
IIEKHHNG_00123 2.95e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
IIEKHHNG_00124 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
IIEKHHNG_00125 0.0 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
IIEKHHNG_00126 1.41e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
IIEKHHNG_00127 3.62e-111 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IIEKHHNG_00129 1.18e-174 yhaR - - I - - - enoyl-CoA hydratase
IIEKHHNG_00130 5.99e-21 - - - S - - - YhzD-like protein
IIEKHHNG_00131 3.92e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_00132 4.82e-277 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
IIEKHHNG_00133 7.47e-300 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
IIEKHHNG_00134 0.0 yhaN - - L - - - AAA domain
IIEKHHNG_00135 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
IIEKHHNG_00136 4.95e-44 yhaL - - S - - - Sporulation protein YhaL
IIEKHHNG_00137 1.36e-183 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IIEKHHNG_00138 1.29e-123 yhaK - - S - - - Putative zincin peptidase
IIEKHHNG_00139 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
IIEKHHNG_00140 4.73e-146 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
IIEKHHNG_00141 4.74e-55 yhaH - - S - - - YtxH-like protein
IIEKHHNG_00142 2.55e-24 - - - - - - - -
IIEKHHNG_00143 1.43e-100 trpP - - S - - - Tryptophan transporter TrpP
IIEKHHNG_00144 5.91e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IIEKHHNG_00145 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IIEKHHNG_00146 3.02e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
IIEKHHNG_00147 6.41e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
IIEKHHNG_00148 1.75e-161 ecsC - - S - - - EcsC protein family
IIEKHHNG_00149 1.53e-286 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IIEKHHNG_00150 3.98e-311 yhfA - - C - - - membrane
IIEKHHNG_00151 3.1e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
IIEKHHNG_00152 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IIEKHHNG_00153 8.58e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IIEKHHNG_00154 4.49e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
IIEKHHNG_00155 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IIEKHHNG_00156 4.41e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_00157 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
IIEKHHNG_00158 5.92e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IIEKHHNG_00160 2.11e-250 yhfE - - G - - - peptidase M42
IIEKHHNG_00161 3.43e-282 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIEKHHNG_00163 4.01e-181 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IIEKHHNG_00164 6.47e-242 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
IIEKHHNG_00165 1.05e-141 yhfK - - GM - - - NmrA-like family
IIEKHHNG_00166 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IIEKHHNG_00167 7.96e-85 yhfM - - - - - - -
IIEKHHNG_00168 3.56e-298 yhfN - - O - - - Peptidase M48
IIEKHHNG_00169 1.57e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IIEKHHNG_00170 7.33e-192 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IIEKHHNG_00171 6.03e-134 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
IIEKHHNG_00172 2.38e-251 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IIEKHHNG_00173 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IIEKHHNG_00174 7.56e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
IIEKHHNG_00175 1.87e-275 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
IIEKHHNG_00176 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
IIEKHHNG_00177 3.88e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIEKHHNG_00178 3.87e-42 yhzC - - S - - - IDEAL
IIEKHHNG_00179 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
IIEKHHNG_00180 2.09e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IIEKHHNG_00181 4.93e-82 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IIEKHHNG_00182 8.25e-161 yrpD - - S - - - Domain of unknown function, YrpD
IIEKHHNG_00183 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
IIEKHHNG_00184 2.64e-63 - - - S - - - Belongs to the UPF0145 family
IIEKHHNG_00185 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IIEKHHNG_00186 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
IIEKHHNG_00187 4.12e-79 yhjD - - - - - - -
IIEKHHNG_00188 2.23e-142 yhjE - - S - - - SNARE associated Golgi protein
IIEKHHNG_00189 3.32e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IIEKHHNG_00190 0.0 yhjG - - CH - - - FAD binding domain
IIEKHHNG_00191 4.89e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
IIEKHHNG_00192 9.85e-262 yhjN - - S ko:K07120 - ko00000 membrane
IIEKHHNG_00193 1.78e-266 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IIEKHHNG_00194 1.06e-139 - - - K - - - QacR-like protein, C-terminal region
IIEKHHNG_00195 3.6e-122 yhjR - - S - - - Rubrerythrin
IIEKHHNG_00196 5.11e-153 ydfS - - S - - - Protein of unknown function (DUF421)
IIEKHHNG_00197 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
IIEKHHNG_00198 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
IIEKHHNG_00199 4.7e-283 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IIEKHHNG_00200 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
IIEKHHNG_00201 6.24e-66 yisB - - V - - - COG1403 Restriction endonuclease
IIEKHHNG_00202 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
IIEKHHNG_00203 1.09e-82 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
IIEKHHNG_00204 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
IIEKHHNG_00205 8.51e-109 gerPC - - S ko:K06301 - ko00000 Spore germination protein
IIEKHHNG_00206 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
IIEKHHNG_00207 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
IIEKHHNG_00208 1.59e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
IIEKHHNG_00209 1.54e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IIEKHHNG_00210 2.22e-78 yisL - - S - - - UPF0344 protein
IIEKHHNG_00211 2.17e-123 yisN - - S - - - Protein of unknown function (DUF2777)
IIEKHHNG_00212 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IIEKHHNG_00213 1.81e-169 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
IIEKHHNG_00214 6.12e-312 yisQ - - V - - - Mate efflux family protein
IIEKHHNG_00215 4.72e-206 yisR - - K - - - Transcriptional regulator
IIEKHHNG_00216 4.31e-31 - 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
IIEKHHNG_00217 1.48e-114 yisT - - S - - - DinB family
IIEKHHNG_00218 1.71e-95 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
IIEKHHNG_00219 5.57e-238 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIEKHHNG_00220 1.6e-103 yisX - - S - - - Pentapeptide repeats (9 copies)
IIEKHHNG_00221 1.8e-104 - - - S - - - Acetyltransferase (GNAT) domain
IIEKHHNG_00222 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IIEKHHNG_00223 3.69e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
IIEKHHNG_00224 7.54e-205 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
IIEKHHNG_00225 8.51e-219 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
IIEKHHNG_00226 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
IIEKHHNG_00227 1.79e-307 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
IIEKHHNG_00229 5.5e-203 yitS - - S - - - protein conserved in bacteria
IIEKHHNG_00230 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IIEKHHNG_00231 6.41e-106 ipi - - S - - - Intracellular proteinase inhibitor
IIEKHHNG_00232 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
IIEKHHNG_00233 1.49e-11 - - - - - - - -
IIEKHHNG_00234 5.08e-197 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IIEKHHNG_00235 8.73e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IIEKHHNG_00236 1.33e-67 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
IIEKHHNG_00237 1.12e-103 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IIEKHHNG_00238 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
IIEKHHNG_00239 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
IIEKHHNG_00240 5.84e-252 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IIEKHHNG_00241 2.99e-289 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IIEKHHNG_00242 5.17e-175 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
IIEKHHNG_00243 3.98e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
IIEKHHNG_00244 2.31e-257 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IIEKHHNG_00245 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
IIEKHHNG_00246 8.28e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IIEKHHNG_00247 7.21e-39 yjzC - - S - - - YjzC-like protein
IIEKHHNG_00248 1.24e-31 yjzD - - S - - - Protein of unknown function (DUF2929)
IIEKHHNG_00249 3.04e-176 yjaU - - I - - - carboxylic ester hydrolase activity
IIEKHHNG_00250 1.67e-134 yjaV - - - - - - -
IIEKHHNG_00251 4.67e-213 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
IIEKHHNG_00252 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
IIEKHHNG_00253 2.72e-42 yjzB - - - - - - -
IIEKHHNG_00254 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IIEKHHNG_00255 9.08e-299 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IIEKHHNG_00256 7.48e-190 yjaZ - - O - - - Zn-dependent protease
IIEKHHNG_00257 8.37e-232 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IIEKHHNG_00258 7.23e-238 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IIEKHHNG_00259 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
IIEKHHNG_00260 5.76e-217 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIEKHHNG_00261 1.67e-198 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIEKHHNG_00262 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
IIEKHHNG_00263 4.85e-232 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
IIEKHHNG_00264 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IIEKHHNG_00265 1.46e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIEKHHNG_00266 6.93e-208 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIEKHHNG_00267 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IIEKHHNG_00268 1.42e-216 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IIEKHHNG_00269 3.5e-295 - - - S - - - Putative glycosyl hydrolase domain
IIEKHHNG_00270 2.55e-131 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIEKHHNG_00271 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IIEKHHNG_00272 4.59e-140 yjbE - - P - - - Integral membrane protein TerC family
IIEKHHNG_00273 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IIEKHHNG_00274 9.45e-281 coiA - - S ko:K06198 - ko00000 Competence protein
IIEKHHNG_00275 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
IIEKHHNG_00276 1.06e-25 - - - - - - - -
IIEKHHNG_00277 1.22e-219 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IIEKHHNG_00278 2.03e-92 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
IIEKHHNG_00279 3.12e-152 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IIEKHHNG_00280 1.72e-128 yjbK - - S - - - protein conserved in bacteria
IIEKHHNG_00281 4.78e-79 yjbL - - S - - - Belongs to the UPF0738 family
IIEKHHNG_00282 1.56e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
IIEKHHNG_00283 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IIEKHHNG_00284 2.35e-211 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IIEKHHNG_00285 3.05e-183 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IIEKHHNG_00286 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IIEKHHNG_00287 5.26e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IIEKHHNG_00288 8.09e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
IIEKHHNG_00289 4.57e-268 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
IIEKHHNG_00290 5.5e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
IIEKHHNG_00291 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IIEKHHNG_00292 1.52e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IIEKHHNG_00293 4.3e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IIEKHHNG_00294 6.85e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
IIEKHHNG_00295 7.96e-124 yjbX - - S - - - Spore coat protein
IIEKHHNG_00296 2.1e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
IIEKHHNG_00297 2.48e-120 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
IIEKHHNG_00298 1.51e-99 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
IIEKHHNG_00299 4.1e-43 cotW - - - ko:K06341 - ko00000 -
IIEKHHNG_00300 9.7e-71 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
IIEKHHNG_00301 8.37e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
IIEKHHNG_00304 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IIEKHHNG_00305 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
IIEKHHNG_00306 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IIEKHHNG_00307 2.48e-48 - - - - - - - -
IIEKHHNG_00308 2.06e-181 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
IIEKHHNG_00309 4.59e-160 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IIEKHHNG_00310 3.53e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IIEKHHNG_00311 4.32e-48 - - - K - - - SpoVT / AbrB like domain
IIEKHHNG_00312 2.48e-96 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIEKHHNG_00313 6.97e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
IIEKHHNG_00314 1.23e-164 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
IIEKHHNG_00315 3.93e-271 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IIEKHHNG_00316 1.37e-271 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IIEKHHNG_00318 1.14e-26 - - - - - - - -
IIEKHHNG_00319 1.42e-29 - - - - - - - -
IIEKHHNG_00320 9.34e-51 - - - - - - - -
IIEKHHNG_00322 4.74e-247 - - - M - - - nucleic acid phosphodiester bond hydrolysis
IIEKHHNG_00326 3.27e-78 - - - E - - - Glyoxalase-like domain
IIEKHHNG_00327 1.64e-210 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
IIEKHHNG_00328 3.12e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
IIEKHHNG_00329 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
IIEKHHNG_00330 1.06e-106 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IIEKHHNG_00331 1.34e-281 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
IIEKHHNG_00332 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IIEKHHNG_00333 2.09e-242 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IIEKHHNG_00334 4.28e-274 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IIEKHHNG_00335 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIEKHHNG_00336 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IIEKHHNG_00337 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IIEKHHNG_00338 1.62e-176 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IIEKHHNG_00339 1.62e-158 - - - S - - - Haloacid dehalogenase-like hydrolase
IIEKHHNG_00340 1.69e-46 - - - - - - - -
IIEKHHNG_00341 1.19e-68 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IIEKHHNG_00342 2.89e-135 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
IIEKHHNG_00344 1.91e-31 yjfB - - S - - - Putative motility protein
IIEKHHNG_00345 1.48e-90 yjgA - - T - - - Protein of unknown function (DUF2809)
IIEKHHNG_00346 3.92e-129 yjgB - - S - - - Domain of unknown function (DUF4309)
IIEKHHNG_00347 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
IIEKHHNG_00348 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
IIEKHHNG_00349 3.25e-291 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IIEKHHNG_00350 1.64e-283 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IIEKHHNG_00351 1.73e-40 - - - - - - - -
IIEKHHNG_00352 3.93e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IIEKHHNG_00353 3.6e-158 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
IIEKHHNG_00354 3.08e-166 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
IIEKHHNG_00355 2.38e-226 yjlA - - EG - - - Putative multidrug resistance efflux transporter
IIEKHHNG_00356 4.96e-118 yjlB - - S - - - Cupin domain
IIEKHHNG_00357 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
IIEKHHNG_00358 1.76e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IIEKHHNG_00359 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
IIEKHHNG_00360 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
IIEKHHNG_00361 1.24e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
IIEKHHNG_00362 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
IIEKHHNG_00363 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
IIEKHHNG_00364 1.83e-112 - - - T - - - Transcriptional regulatory protein, C terminal
IIEKHHNG_00365 4.91e-167 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IIEKHHNG_00366 1.11e-132 - - - V ko:K01990,ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_00367 7.74e-86 - - - S - - - ABC-2 family transporter protein
IIEKHHNG_00369 4.67e-50 - 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_00370 1.26e-75 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIEKHHNG_00372 0.0 lcnDR2 - - V - - - Lanthionine synthetase C-like protein
IIEKHHNG_00373 2.77e-276 lanT - - V ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 Peptidase C39 family
IIEKHHNG_00376 3.25e-243 lcnDR2 - - V - - - Domain of unknown function (DUF4135)
IIEKHHNG_00377 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
IIEKHHNG_00378 8.38e-103 yjoA - - S - - - DinB family
IIEKHHNG_00379 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IIEKHHNG_00381 1.94e-220 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IIEKHHNG_00382 9.51e-81 yjqA - - S - - - Bacterial PH domain
IIEKHHNG_00383 2.63e-142 yjqB - - S - - - phage-related replication protein
IIEKHHNG_00384 6.51e-145 xkdA - - E - - - IrrE N-terminal-like domain
IIEKHHNG_00385 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
IIEKHHNG_00387 2.94e-194 xkdC - - L - - - Bacterial dnaA protein
IIEKHHNG_00391 3.05e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IIEKHHNG_00392 1.24e-142 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
IIEKHHNG_00393 1.36e-262 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
IIEKHHNG_00394 5.17e-304 xkdE3 - - S - - - portal protein
IIEKHHNG_00395 8.8e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
IIEKHHNG_00396 8.3e-203 xkdG - - S - - - Phage capsid family
IIEKHHNG_00397 3.6e-60 yqbG - - S - - - Protein of unknown function (DUF3199)
IIEKHHNG_00398 1.42e-56 - - - S - - - Domain of unknown function (DUF3599)
IIEKHHNG_00399 8.03e-76 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
IIEKHHNG_00400 1.05e-74 xkdJ - - - - - - -
IIEKHHNG_00401 1.45e-20 - - - - - - - -
IIEKHHNG_00402 2.31e-287 xkdK - - S - - - Phage tail sheath C-terminal domain
IIEKHHNG_00403 8.21e-97 xkdM - - S - - - Phage tail tube protein
IIEKHHNG_00404 2.09e-95 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
IIEKHHNG_00405 4.33e-27 - - - - - - - -
IIEKHHNG_00406 5.5e-272 xkdO - - L - - - Transglycosylase SLT domain
IIEKHHNG_00407 6.56e-145 xkdP - - S - - - Lysin motif
IIEKHHNG_00408 2.66e-206 xkdQ - - G - - - NLP P60 protein
IIEKHHNG_00409 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
IIEKHHNG_00410 4.74e-75 xkdS - - S - - - Protein of unknown function (DUF2634)
IIEKHHNG_00411 4.38e-212 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IIEKHHNG_00412 4.1e-112 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
IIEKHHNG_00413 8.92e-38 - - - - - - - -
IIEKHHNG_00414 4.87e-109 - - - - - - - -
IIEKHHNG_00416 1.32e-39 xkdX - - - - - - -
IIEKHHNG_00417 3.67e-177 xepA - - - - - - -
IIEKHHNG_00418 3.87e-51 xhlA - - S - - - Haemolysin XhlA
IIEKHHNG_00419 4.7e-52 xhlB - - S - - - SPP1 phage holin
IIEKHHNG_00420 2.02e-214 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
IIEKHHNG_00421 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
IIEKHHNG_00422 1.89e-172 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
IIEKHHNG_00423 1.22e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
IIEKHHNG_00424 1.2e-140 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
IIEKHHNG_00425 1.33e-311 steT - - E ko:K03294 - ko00000 amino acid
IIEKHHNG_00426 4.3e-228 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IIEKHHNG_00427 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IIEKHHNG_00428 1.56e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IIEKHHNG_00430 1.07e-275 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IIEKHHNG_00431 0.0 yubD - - P - - - Major Facilitator Superfamily
IIEKHHNG_00432 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
IIEKHHNG_00433 3.98e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIEKHHNG_00434 1.89e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIEKHHNG_00435 4.37e-241 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IIEKHHNG_00436 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IIEKHHNG_00437 1.09e-223 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
IIEKHHNG_00438 4.3e-255 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IIEKHHNG_00439 2.55e-216 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IIEKHHNG_00440 6.62e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IIEKHHNG_00441 3.43e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
IIEKHHNG_00442 3.44e-203 ykgA - - E - - - Amidinotransferase
IIEKHHNG_00443 3.06e-120 ykhA - - I - - - Acyl-CoA hydrolase
IIEKHHNG_00444 7.43e-130 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IIEKHHNG_00445 2.37e-68 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
IIEKHHNG_00446 4.97e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
IIEKHHNG_00447 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IIEKHHNG_00448 1.77e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IIEKHHNG_00449 7.94e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IIEKHHNG_00450 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
IIEKHHNG_00451 9.88e-111 ohrR - - K - - - COG1846 Transcriptional regulators
IIEKHHNG_00452 3.2e-91 ohrB - - O - - - Organic hydroperoxide resistance protein
IIEKHHNG_00453 6.7e-82 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IIEKHHNG_00455 7.1e-275 - - - M - - - Glycosyl transferase family 2
IIEKHHNG_00456 5.25e-177 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
IIEKHHNG_00457 1.98e-133 - - - S - - - AAA ATPase domain
IIEKHHNG_00458 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IIEKHHNG_00459 2.58e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IIEKHHNG_00460 1.28e-189 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IIEKHHNG_00461 2.18e-169 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
IIEKHHNG_00462 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_00463 4.66e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
IIEKHHNG_00464 1.27e-309 ydhD - - M - - - Glycosyl hydrolase
IIEKHHNG_00466 3.52e-309 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
IIEKHHNG_00467 1.23e-69 tnrA - - K - - - transcriptional
IIEKHHNG_00468 1.11e-23 - - - - - - - -
IIEKHHNG_00469 5.25e-37 ykoL - - - - - - -
IIEKHHNG_00470 1.98e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
IIEKHHNG_00471 3.81e-129 ykoP - - G - - - polysaccharide deacetylase
IIEKHHNG_00472 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
IIEKHHNG_00473 3.42e-202 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IIEKHHNG_00474 1.43e-131 ykoX - - S - - - membrane-associated protein
IIEKHHNG_00475 2.91e-173 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IIEKHHNG_00476 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIEKHHNG_00477 3.6e-250 ykrI - - S - - - Anti-sigma factor N-terminus
IIEKHHNG_00478 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
IIEKHHNG_00479 1.62e-161 ykrK - - S - - - Domain of unknown function (DUF1836)
IIEKHHNG_00480 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
IIEKHHNG_00481 1.62e-309 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
IIEKHHNG_00482 3e-148 - - - S - - - Protein of unknown function (DUF421)
IIEKHHNG_00483 3.07e-32 ykzE - - - - - - -
IIEKHHNG_00484 3.74e-241 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
IIEKHHNG_00485 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_00486 1.31e-113 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IIEKHHNG_00488 4.44e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IIEKHHNG_00489 2.44e-287 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IIEKHHNG_00490 1.57e-190 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IIEKHHNG_00491 1.04e-290 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IIEKHHNG_00492 7.51e-287 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IIEKHHNG_00493 9.47e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IIEKHHNG_00494 2.61e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IIEKHHNG_00495 2.05e-121 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IIEKHHNG_00497 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IIEKHHNG_00498 3.91e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
IIEKHHNG_00499 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IIEKHHNG_00500 7.27e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IIEKHHNG_00501 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
IIEKHHNG_00502 1.73e-228 ykvI - - S - - - membrane
IIEKHHNG_00503 6.57e-254 - - - - - - - -
IIEKHHNG_00504 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IIEKHHNG_00505 6.25e-103 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
IIEKHHNG_00506 1.76e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IIEKHHNG_00507 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IIEKHHNG_00509 2.54e-77 ykvN - - K - - - Transcriptional regulator
IIEKHHNG_00510 2.47e-168 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IIEKHHNG_00511 3.91e-42 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IIEKHHNG_00512 6e-59 ykvR - - S - - - Protein of unknown function (DUF3219)
IIEKHHNG_00513 5.43e-35 ykvS - - S - - - protein conserved in bacteria
IIEKHHNG_00514 7.17e-39 - - - - - - - -
IIEKHHNG_00515 8.42e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
IIEKHHNG_00516 2.66e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IIEKHHNG_00517 8.57e-114 stoA - - CO - - - thiol-disulfide
IIEKHHNG_00518 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IIEKHHNG_00519 4.71e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IIEKHHNG_00521 1.01e-224 ykvZ - - K - - - Transcriptional regulator
IIEKHHNG_00522 4.61e-198 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
IIEKHHNG_00523 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IIEKHHNG_00524 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
IIEKHHNG_00525 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IIEKHHNG_00526 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_00527 3.53e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
IIEKHHNG_00528 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IIEKHHNG_00529 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IIEKHHNG_00530 2.94e-168 ykwD - - J - - - protein with SCP PR1 domains
IIEKHHNG_00531 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IIEKHHNG_00532 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_00533 3.28e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IIEKHHNG_00534 6.38e-15 - - - - - - - -
IIEKHHNG_00535 3.2e-212 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
IIEKHHNG_00536 5.07e-108 ykyB - - S - - - YkyB-like protein
IIEKHHNG_00537 4.6e-308 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IIEKHHNG_00538 2.55e-116 ykuD - - S - - - protein conserved in bacteria
IIEKHHNG_00539 3.66e-197 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
IIEKHHNG_00540 1.5e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIEKHHNG_00542 1.82e-295 ykuI - - T - - - Diguanylate phosphodiesterase
IIEKHHNG_00543 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
IIEKHHNG_00544 4.35e-120 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
IIEKHHNG_00545 3.09e-35 ykzF - - S - - - Antirepressor AbbA
IIEKHHNG_00546 8.55e-99 ykuL - - S - - - CBS domain
IIEKHHNG_00547 1.32e-215 ccpC - - K - - - Transcriptional regulator
IIEKHHNG_00548 6.12e-115 ykuN - - C ko:K03839 - ko00000 Flavodoxin
IIEKHHNG_00549 1.95e-219 ykuO - - - - - - -
IIEKHHNG_00550 2.16e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
IIEKHHNG_00551 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IIEKHHNG_00552 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IIEKHHNG_00553 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
IIEKHHNG_00554 1.73e-178 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
IIEKHHNG_00555 1.92e-102 ykuV - - CO - - - thiol-disulfide
IIEKHHNG_00556 3.04e-126 rok - - K - - - Repressor of ComK
IIEKHHNG_00557 6.93e-216 yknT - - - ko:K06437 - ko00000 -
IIEKHHNG_00558 1.93e-139 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IIEKHHNG_00559 1.41e-240 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IIEKHHNG_00560 2.78e-309 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
IIEKHHNG_00561 3.21e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
IIEKHHNG_00562 7.17e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
IIEKHHNG_00563 2.06e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IIEKHHNG_00564 7.69e-139 yknW - - S - - - Yip1 domain
IIEKHHNG_00565 1.64e-245 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IIEKHHNG_00566 2.38e-157 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_00567 2.98e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
IIEKHHNG_00568 9.28e-170 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_00569 5.54e-213 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
IIEKHHNG_00570 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IIEKHHNG_00571 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IIEKHHNG_00572 3.68e-50 ykoA - - - - - - -
IIEKHHNG_00573 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IIEKHHNG_00574 1.08e-214 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIEKHHNG_00575 1.2e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
IIEKHHNG_00576 4.47e-18 - - - S - - - Uncharacterized protein YkpC
IIEKHHNG_00577 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
IIEKHHNG_00578 6.37e-60 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
IIEKHHNG_00579 1.68e-312 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IIEKHHNG_00580 5.27e-197 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
IIEKHHNG_00581 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IIEKHHNG_00582 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IIEKHHNG_00583 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIEKHHNG_00584 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
IIEKHHNG_00585 1.51e-187 ykrA - - S - - - hydrolases of the HAD superfamily
IIEKHHNG_00586 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IIEKHHNG_00587 7.91e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IIEKHHNG_00588 1.32e-132 ykyA - - L - - - Putative cell-wall binding lipoprotein
IIEKHHNG_00589 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IIEKHHNG_00590 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IIEKHHNG_00591 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
IIEKHHNG_00592 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IIEKHHNG_00593 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IIEKHHNG_00594 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IIEKHHNG_00595 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IIEKHHNG_00596 0.0 - - - IQ - - - Phosphopantetheine attachment site
IIEKHHNG_00597 3.73e-264 - - - V - - - Beta-lactamase
IIEKHHNG_00598 2.72e-261 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IIEKHHNG_00599 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IIEKHHNG_00600 2.08e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IIEKHHNG_00601 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IIEKHHNG_00602 7.97e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
IIEKHHNG_00603 8.08e-192 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
IIEKHHNG_00604 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
IIEKHHNG_00605 3.83e-56 yktA - - S - - - Belongs to the UPF0223 family
IIEKHHNG_00606 8.15e-155 yktB - - S - - - Belongs to the UPF0637 family
IIEKHHNG_00607 3.33e-33 ykzI - - - - - - -
IIEKHHNG_00608 7.8e-194 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
IIEKHHNG_00609 1.07e-107 ykzC - - S - - - Acetyltransferase (GNAT) family
IIEKHHNG_00610 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
IIEKHHNG_00612 2.83e-62 ylaE - - - - - - -
IIEKHHNG_00613 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
IIEKHHNG_00614 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
IIEKHHNG_00615 2.44e-65 - - - S - - - YlaH-like protein
IIEKHHNG_00616 6.78e-46 ylaI - - S - - - protein conserved in bacteria
IIEKHHNG_00617 5.45e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IIEKHHNG_00618 2.7e-313 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
IIEKHHNG_00619 1.75e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IIEKHHNG_00620 5.18e-221 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IIEKHHNG_00621 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
IIEKHHNG_00622 8.59e-272 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IIEKHHNG_00623 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IIEKHHNG_00624 3.47e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IIEKHHNG_00625 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IIEKHHNG_00626 3.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IIEKHHNG_00627 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IIEKHHNG_00628 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IIEKHHNG_00629 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IIEKHHNG_00630 8.46e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
IIEKHHNG_00631 4.12e-79 ylbA - - S - - - YugN-like family
IIEKHHNG_00632 9.59e-96 ylbB - - T - - - COG0517 FOG CBS domain
IIEKHHNG_00633 3.97e-255 ylbC - - S - - - protein with SCP PR1 domains
IIEKHHNG_00634 1.03e-87 ylbD - - S - - - Putative coat protein
IIEKHHNG_00635 1.73e-48 ylbE - - S - - - YlbE-like protein
IIEKHHNG_00636 2.74e-96 ylbF - - S - - - Belongs to the UPF0342 family
IIEKHHNG_00637 3.94e-57 ylbG - - S - - - UPF0298 protein
IIEKHHNG_00638 7.68e-116 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
IIEKHHNG_00639 8.3e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IIEKHHNG_00640 9.73e-276 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
IIEKHHNG_00641 2.48e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IIEKHHNG_00642 8.8e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
IIEKHHNG_00643 5.23e-295 ylbM - - S - - - Belongs to the UPF0348 family
IIEKHHNG_00644 3.3e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
IIEKHHNG_00645 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
IIEKHHNG_00646 1.27e-110 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IIEKHHNG_00647 1.14e-116 ylbP - - K - - - n-acetyltransferase
IIEKHHNG_00648 2.85e-210 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIEKHHNG_00649 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IIEKHHNG_00650 1.03e-100 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
IIEKHHNG_00651 8.23e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IIEKHHNG_00652 2.4e-68 ftsL - - D - - - Essential cell division protein
IIEKHHNG_00653 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IIEKHHNG_00654 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
IIEKHHNG_00655 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IIEKHHNG_00656 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IIEKHHNG_00657 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IIEKHHNG_00658 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IIEKHHNG_00659 3.29e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IIEKHHNG_00660 7.87e-213 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
IIEKHHNG_00661 2.67e-179 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IIEKHHNG_00662 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IIEKHHNG_00663 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IIEKHHNG_00664 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
IIEKHHNG_00665 8.23e-218 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IIEKHHNG_00666 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIEKHHNG_00667 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIEKHHNG_00668 8.04e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IIEKHHNG_00669 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
IIEKHHNG_00670 7.13e-52 ylmC - - S - - - sporulation protein
IIEKHHNG_00671 9.55e-206 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
IIEKHHNG_00672 3.68e-161 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IIEKHHNG_00673 4.61e-85 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IIEKHHNG_00674 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
IIEKHHNG_00675 6.12e-182 ylmH - - S - - - conserved protein, contains S4-like domain
IIEKHHNG_00676 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
IIEKHHNG_00677 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IIEKHHNG_00678 4.75e-80 ylyA - - T - - - COG1734 DnaK suppressor protein
IIEKHHNG_00679 1.02e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IIEKHHNG_00680 5.35e-216 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IIEKHHNG_00681 8.98e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IIEKHHNG_00682 2.81e-296 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
IIEKHHNG_00683 1.47e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
IIEKHHNG_00684 1.55e-314 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IIEKHHNG_00685 8.86e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IIEKHHNG_00686 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
IIEKHHNG_00687 1.18e-179 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IIEKHHNG_00688 7.36e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IIEKHHNG_00689 3.66e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IIEKHHNG_00690 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IIEKHHNG_00692 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
IIEKHHNG_00693 1.21e-228 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
IIEKHHNG_00694 1.77e-283 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
IIEKHHNG_00695 6.76e-143 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
IIEKHHNG_00696 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IIEKHHNG_00697 4.15e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
IIEKHHNG_00698 6.27e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
IIEKHHNG_00699 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
IIEKHHNG_00700 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
IIEKHHNG_00701 2.14e-198 yloC - - S - - - stress-induced protein
IIEKHHNG_00702 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
IIEKHHNG_00703 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
IIEKHHNG_00704 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IIEKHHNG_00705 2.09e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IIEKHHNG_00706 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IIEKHHNG_00707 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IIEKHHNG_00708 2.64e-221 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IIEKHHNG_00709 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IIEKHHNG_00710 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IIEKHHNG_00711 2.03e-177 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
IIEKHHNG_00712 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
IIEKHHNG_00713 6.22e-211 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IIEKHHNG_00714 3.42e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
IIEKHHNG_00715 4.34e-152 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
IIEKHHNG_00716 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
IIEKHHNG_00717 3.65e-78 yloU - - S - - - protein conserved in bacteria
IIEKHHNG_00718 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
IIEKHHNG_00719 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IIEKHHNG_00720 9.75e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IIEKHHNG_00721 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IIEKHHNG_00722 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IIEKHHNG_00723 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IIEKHHNG_00724 3.76e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IIEKHHNG_00725 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IIEKHHNG_00726 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIEKHHNG_00727 1.23e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IIEKHHNG_00728 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
IIEKHHNG_00729 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IIEKHHNG_00730 1.57e-184 - - - S - - - Phosphotransferase enzyme family
IIEKHHNG_00731 8.01e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IIEKHHNG_00732 1.47e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IIEKHHNG_00733 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
IIEKHHNG_00734 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
IIEKHHNG_00735 3.41e-80 ylqD - - S - - - YlqD protein
IIEKHHNG_00736 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IIEKHHNG_00737 5.67e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
IIEKHHNG_00738 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IIEKHHNG_00739 5.09e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IIEKHHNG_00740 3.37e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIEKHHNG_00741 0.0 ylqG - - - - - - -
IIEKHHNG_00742 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
IIEKHHNG_00743 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IIEKHHNG_00744 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IIEKHHNG_00745 7.32e-216 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
IIEKHHNG_00746 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IIEKHHNG_00747 3.83e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IIEKHHNG_00748 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
IIEKHHNG_00749 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IIEKHHNG_00750 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IIEKHHNG_00751 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IIEKHHNG_00752 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IIEKHHNG_00753 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
IIEKHHNG_00754 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
IIEKHHNG_00755 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
IIEKHHNG_00756 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IIEKHHNG_00757 1.96e-122 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
IIEKHHNG_00758 5.19e-309 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IIEKHHNG_00759 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
IIEKHHNG_00760 1.98e-88 ylxF - - S - - - MgtE intracellular N domain
IIEKHHNG_00761 3e-260 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
IIEKHHNG_00762 8.9e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
IIEKHHNG_00763 2.79e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
IIEKHHNG_00764 1.81e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
IIEKHHNG_00765 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IIEKHHNG_00766 8.47e-245 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IIEKHHNG_00767 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
IIEKHHNG_00768 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
IIEKHHNG_00769 1.48e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
IIEKHHNG_00770 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
IIEKHHNG_00771 5.74e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
IIEKHHNG_00772 2.53e-242 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IIEKHHNG_00773 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IIEKHHNG_00774 7.94e-250 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
IIEKHHNG_00775 6.35e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
IIEKHHNG_00776 1.42e-248 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IIEKHHNG_00777 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
IIEKHHNG_00778 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
IIEKHHNG_00779 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IIEKHHNG_00780 2.86e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IIEKHHNG_00781 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIEKHHNG_00782 5.85e-94 ylxL - - - - - - -
IIEKHHNG_00783 7.07e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
IIEKHHNG_00784 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IIEKHHNG_00785 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
IIEKHHNG_00786 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IIEKHHNG_00787 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IIEKHHNG_00788 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
IIEKHHNG_00789 2.57e-272 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IIEKHHNG_00790 1.15e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
IIEKHHNG_00791 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IIEKHHNG_00792 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIEKHHNG_00793 1.9e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
IIEKHHNG_00794 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
IIEKHHNG_00795 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
IIEKHHNG_00796 6.16e-63 ylxQ - - J - - - ribosomal protein
IIEKHHNG_00797 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IIEKHHNG_00798 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
IIEKHHNG_00799 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IIEKHHNG_00800 1.73e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IIEKHHNG_00801 2.6e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
IIEKHHNG_00802 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IIEKHHNG_00803 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IIEKHHNG_00804 4.15e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
IIEKHHNG_00805 5.91e-299 mlpA - - S - - - Belongs to the peptidase M16 family
IIEKHHNG_00806 2.17e-56 ymxH - - S - - - YlmC YmxH family
IIEKHHNG_00807 4.51e-204 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
IIEKHHNG_00808 1.36e-137 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IIEKHHNG_00809 1.74e-249 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IIEKHHNG_00810 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IIEKHHNG_00811 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IIEKHHNG_00812 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIEKHHNG_00813 2.27e-166 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
IIEKHHNG_00814 6.32e-42 - - - S - - - YlzJ-like protein
IIEKHHNG_00815 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IIEKHHNG_00816 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_00817 3.16e-296 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IIEKHHNG_00818 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IIEKHHNG_00819 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
IIEKHHNG_00820 1.12e-306 albE - - S - - - Peptidase M16
IIEKHHNG_00821 8.28e-310 ymfH - - S - - - zinc protease
IIEKHHNG_00822 2.88e-164 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IIEKHHNG_00823 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
IIEKHHNG_00824 3.14e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
IIEKHHNG_00825 5.76e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
IIEKHHNG_00826 9.58e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IIEKHHNG_00827 4.64e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
IIEKHHNG_00828 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IIEKHHNG_00829 5.01e-275 pbpX - - V - - - Beta-lactamase
IIEKHHNG_00830 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
IIEKHHNG_00831 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
IIEKHHNG_00832 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
IIEKHHNG_00833 8.3e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IIEKHHNG_00834 7.11e-274 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IIEKHHNG_00835 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IIEKHHNG_00836 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
IIEKHHNG_00837 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
IIEKHHNG_00838 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IIEKHHNG_00839 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IIEKHHNG_00841 1.16e-165 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
IIEKHHNG_00842 1.35e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IIEKHHNG_00843 3.7e-233 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
IIEKHHNG_00844 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IIEKHHNG_00845 5.27e-49 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
IIEKHHNG_00846 3.63e-309 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
IIEKHHNG_00847 5.05e-186 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
IIEKHHNG_00848 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
IIEKHHNG_00849 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IIEKHHNG_00850 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IIEKHHNG_00851 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IIEKHHNG_00852 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IIEKHHNG_00853 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
IIEKHHNG_00854 6.55e-292 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IIEKHHNG_00855 4.27e-102 nucB - - M - - - Deoxyribonuclease NucA/NucB
IIEKHHNG_00856 4.46e-153 yoaK - - S - - - Membrane
IIEKHHNG_00857 2.78e-82 ymzB - - - - - - -
IIEKHHNG_00858 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
IIEKHHNG_00859 4.29e-06 - - - - - - - -
IIEKHHNG_00860 5.4e-161 ymaC - - S - - - Replication protein
IIEKHHNG_00861 1.11e-100 ymaD - - O - - - redox protein, regulator of disulfide bond formation
IIEKHHNG_00862 5.05e-70 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IIEKHHNG_00863 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IIEKHHNG_00865 5.96e-77 ymaF - - S - - - YmaF family
IIEKHHNG_00866 7.32e-219 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IIEKHHNG_00867 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IIEKHHNG_00868 2.86e-57 - - - - - - - -
IIEKHHNG_00869 9.42e-29 ymzA - - - - - - -
IIEKHHNG_00870 1.61e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
IIEKHHNG_00871 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIEKHHNG_00872 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIEKHHNG_00873 2.24e-141 ymaB - - S - - - MutT family
IIEKHHNG_00874 1.86e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IIEKHHNG_00875 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
IIEKHHNG_00876 2.7e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IIEKHHNG_00877 1.01e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IIEKHHNG_00878 4.39e-88 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
IIEKHHNG_00879 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
IIEKHHNG_00880 1.03e-28 - - - - - - - -
IIEKHHNG_00881 4.5e-115 - - - - - - - -
IIEKHHNG_00885 2.1e-55 - - - S - - - Protein of unknown function (DUF2568)
IIEKHHNG_00886 4.7e-51 - - - T - - - Histidine kinase
IIEKHHNG_00887 3.19e-265 mrjp - - G - - - Major royal jelly protein
IIEKHHNG_00888 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
IIEKHHNG_00889 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IIEKHHNG_00890 9.04e-278 xylR - - GK - - - ROK family
IIEKHHNG_00891 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
IIEKHHNG_00892 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
IIEKHHNG_00893 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
IIEKHHNG_00897 2.21e-27 - - - - - - - -
IIEKHHNG_00898 8.43e-73 dinB - - S - - - DinB family
IIEKHHNG_00899 8.07e-235 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
IIEKHHNG_00900 3.63e-96 - - - S - - - Bacterial transferase hexapeptide (six repeats)
IIEKHHNG_00901 2.78e-24 - - - - - - - -
IIEKHHNG_00903 2.75e-39 - - - - - - - -
IIEKHHNG_00905 1.34e-94 yoaP - - K - - - YoaP-like
IIEKHHNG_00906 1.64e-77 yoaP - - K - - - YoaP-like
IIEKHHNG_00907 3.28e-128 - - - J - - - Acetyltransferase (GNAT) domain
IIEKHHNG_00908 4.55e-139 - - - S - - - Domain of unknown function (DUF3885)
IIEKHHNG_00909 6.88e-257 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIEKHHNG_00910 3.33e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
IIEKHHNG_00911 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IIEKHHNG_00914 0.0 yobO - - M - - - Pectate lyase superfamily protein
IIEKHHNG_00915 6.07e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
IIEKHHNG_00916 1.37e-182 yndL - - S - - - Replication protein
IIEKHHNG_00917 1.74e-11 - - - - - - - -
IIEKHHNG_00918 1.04e-183 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
IIEKHHNG_00919 3.2e-95 yndM - - S - - - Protein of unknown function (DUF2512)
IIEKHHNG_00921 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IIEKHHNG_00922 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IIEKHHNG_00923 5.22e-145 yneB - - L - - - resolvase
IIEKHHNG_00924 2.33e-43 ynzC - - S - - - UPF0291 protein
IIEKHHNG_00925 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IIEKHHNG_00926 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
IIEKHHNG_00927 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
IIEKHHNG_00928 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
IIEKHHNG_00929 3.14e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
IIEKHHNG_00930 7.09e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
IIEKHHNG_00931 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
IIEKHHNG_00932 1.18e-98 yneK - - S - - - Protein of unknown function (DUF2621)
IIEKHHNG_00933 7.01e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
IIEKHHNG_00934 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
IIEKHHNG_00935 1.47e-20 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
IIEKHHNG_00936 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IIEKHHNG_00937 8.17e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IIEKHHNG_00939 1.73e-44 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
IIEKHHNG_00940 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
IIEKHHNG_00941 7.79e-70 yneQ - - - - - - -
IIEKHHNG_00942 2.67e-66 yneR - - S - - - Belongs to the HesB IscA family
IIEKHHNG_00943 2.6e-120 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IIEKHHNG_00944 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
IIEKHHNG_00945 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIEKHHNG_00946 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIEKHHNG_00947 5.42e-20 - - - - - - - -
IIEKHHNG_00948 1.82e-63 ynfC - - - - - - -
IIEKHHNG_00949 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IIEKHHNG_00950 1.15e-233 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
IIEKHHNG_00951 1.26e-243 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
IIEKHHNG_00952 5.27e-147 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
IIEKHHNG_00953 3.96e-271 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
IIEKHHNG_00954 5.86e-191 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IIEKHHNG_00955 2.14e-232 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
IIEKHHNG_00956 1.07e-284 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
IIEKHHNG_00957 2e-199 yndG - - S - - - DoxX-like family
IIEKHHNG_00958 4.51e-99 - - - S - - - Domain of unknown function (DUF4166)
IIEKHHNG_00959 0.0 yndJ - - S - - - YndJ-like protein
IIEKHHNG_00960 4.6e-13 yxlH - - EGP - - - Major Facilitator Superfamily
IIEKHHNG_00962 1.44e-270 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
IIEKHHNG_00963 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
IIEKHHNG_00964 1.43e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
IIEKHHNG_00965 5.65e-311 - - - T - - - Histidine kinase
IIEKHHNG_00966 6.28e-163 - - - T - - - Transcriptional regulatory protein, C terminal
IIEKHHNG_00967 8.84e-316 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
IIEKHHNG_00968 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IIEKHHNG_00969 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIEKHHNG_00970 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIEKHHNG_00971 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIEKHHNG_00972 6.75e-288 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IIEKHHNG_00973 1.18e-177 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IIEKHHNG_00974 7.47e-156 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IIEKHHNG_00975 8.91e-162 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IIEKHHNG_00976 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
IIEKHHNG_00977 3.74e-284 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IIEKHHNG_00978 1.12e-246 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IIEKHHNG_00979 7.45e-167 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IIEKHHNG_00980 3.25e-272 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IIEKHHNG_00981 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IIEKHHNG_00982 8.7e-184 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IIEKHHNG_00983 2.26e-95 yngA - - S - - - membrane
IIEKHHNG_00984 3.16e-144 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IIEKHHNG_00985 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
IIEKHHNG_00986 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IIEKHHNG_00987 1.67e-176 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
IIEKHHNG_00988 3.48e-214 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
IIEKHHNG_00989 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
IIEKHHNG_00990 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
IIEKHHNG_00991 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IIEKHHNG_00992 1.79e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IIEKHHNG_00993 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
IIEKHHNG_00994 1.96e-84 yngL - - S - - - Protein of unknown function (DUF1360)
IIEKHHNG_00995 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
IIEKHHNG_00996 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIEKHHNG_00997 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIEKHHNG_00998 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IIEKHHNG_01013 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIEKHHNG_01014 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIEKHHNG_01015 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
IIEKHHNG_01016 3.2e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IIEKHHNG_01017 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
IIEKHHNG_01018 8.47e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IIEKHHNG_01019 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IIEKHHNG_01021 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IIEKHHNG_01022 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIEKHHNG_01023 7.7e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
IIEKHHNG_01024 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IIEKHHNG_01025 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IIEKHHNG_01026 2.29e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IIEKHHNG_01027 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IIEKHHNG_01028 1.23e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
IIEKHHNG_01029 8.27e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IIEKHHNG_01030 8.14e-143 yyaC - - S - - - Sporulation protein YyaC
IIEKHHNG_01031 2.62e-105 yhhY - - K - - - FR47-like protein
IIEKHHNG_01032 4.77e-225 yyaD - - S - - - Membrane
IIEKHHNG_01033 1.82e-45 yyzM - - S - - - protein conserved in bacteria
IIEKHHNG_01034 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IIEKHHNG_01035 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IIEKHHNG_01036 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
IIEKHHNG_01037 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIEKHHNG_01038 4.51e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IIEKHHNG_01039 3.63e-136 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
IIEKHHNG_01040 3.38e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IIEKHHNG_01041 3.29e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
IIEKHHNG_01042 6.62e-230 ccpB - - K - - - Transcriptional regulator
IIEKHHNG_01043 4.88e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIEKHHNG_01044 1.88e-316 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
IIEKHHNG_01045 2.84e-208 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
IIEKHHNG_01046 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
IIEKHHNG_01049 4.54e-91 ynaF - - - - - - -
IIEKHHNG_01050 1.02e-106 - - - - - - - -
IIEKHHNG_01051 1.53e-36 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
IIEKHHNG_01052 6.35e-167 - - - EG - - - EamA-like transporter family
IIEKHHNG_01053 1.29e-313 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIEKHHNG_01054 2.35e-176 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IIEKHHNG_01055 4.21e-212 - - - K - - - Transcriptional regulator
IIEKHHNG_01056 4.76e-87 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
IIEKHHNG_01057 3.34e-211 - - - M - - - Domain of Unknown Function (DUF1259)
IIEKHHNG_01058 1.49e-97 yjcF - - S - - - Acetyltransferase (GNAT) domain
IIEKHHNG_01059 1.3e-99 yybA - - K - - - transcriptional
IIEKHHNG_01060 1.48e-191 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IIEKHHNG_01061 2.77e-89 - - - K - - - Winged helix DNA-binding domain
IIEKHHNG_01062 1.62e-145 ydgI - - C - - - nitroreductase
IIEKHHNG_01063 1.12e-73 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
IIEKHHNG_01064 5.87e-201 - - - G - - - Major Facilitator Superfamily
IIEKHHNG_01065 2.63e-115 - - - S - - - PFAM DinB family protein
IIEKHHNG_01066 3.82e-149 - - - K - - - FCD domain
IIEKHHNG_01067 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IIEKHHNG_01068 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
IIEKHHNG_01069 1.02e-197 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IIEKHHNG_01070 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
IIEKHHNG_01071 4.56e-87 yybR - - K - - - Transcriptional regulator
IIEKHHNG_01072 3.33e-111 cotF - - M ko:K06329 - ko00000 Spore coat protein
IIEKHHNG_01074 1.95e-201 yybS - - S - - - membrane
IIEKHHNG_01075 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
IIEKHHNG_01076 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IIEKHHNG_01077 1.7e-157 - - - KLT - - - COG0515 Serine threonine protein kinase
IIEKHHNG_01078 2.15e-157 - - - S - - - GlcNAc-PI de-N-acetylase
IIEKHHNG_01079 5.98e-302 - - - M - - - Glycosyltransferase Family 4
IIEKHHNG_01080 6.57e-297 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
IIEKHHNG_01081 6.38e-259 - - - S - - - Ecdysteroid kinase
IIEKHHNG_01082 1.79e-305 - - - M - - - Glycosyltransferase Family 4
IIEKHHNG_01083 5.12e-25 yycC - - K - - - YycC-like protein
IIEKHHNG_01085 7.68e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
IIEKHHNG_01086 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
IIEKHHNG_01087 1.57e-94 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIEKHHNG_01088 1.06e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IIEKHHNG_01093 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIEKHHNG_01094 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_01095 0.0 yycH - - S - - - protein conserved in bacteria
IIEKHHNG_01096 2.81e-194 yycI - - S - - - protein conserved in bacteria
IIEKHHNG_01097 5.69e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IIEKHHNG_01098 1.63e-278 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IIEKHHNG_01099 2.5e-14 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIEKHHNG_01100 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IIEKHHNG_01101 2.31e-243 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
IIEKHHNG_01102 0.0 - - - - - - - -
IIEKHHNG_01103 4.27e-257 - - - S - - - Major Facilitator Superfamily
IIEKHHNG_01104 0.0 - - - S - - - ABC transporter
IIEKHHNG_01105 6.44e-189 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
IIEKHHNG_01106 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IIEKHHNG_01107 9.38e-58 sdpR - - K - - - transcriptional
IIEKHHNG_01108 1.99e-89 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
IIEKHHNG_01109 1.95e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
IIEKHHNG_01110 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IIEKHHNG_01111 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IIEKHHNG_01112 9.49e-262 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
IIEKHHNG_01114 2.92e-113 yycN - - K - - - Acetyltransferase
IIEKHHNG_01115 6.14e-233 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
IIEKHHNG_01116 6.82e-171 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IIEKHHNG_01117 2.21e-275 yycP - - - - - - -
IIEKHHNG_01120 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IIEKHHNG_01121 3.12e-116 - - - K - - - NAD+ binding
IIEKHHNG_01122 8.08e-97 - - - F - - - 5-carbamoylmethyl uridine residue modification
IIEKHHNG_01123 0.0 - - - L - - - AAA domain
IIEKHHNG_01124 5.2e-26 - - - - - - - -
IIEKHHNG_01125 9.35e-233 - - - S - - - Fusaric acid resistance protein-like
IIEKHHNG_01126 1.03e-237 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IIEKHHNG_01127 3.73e-119 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
IIEKHHNG_01128 3.46e-77 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IIEKHHNG_01129 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IIEKHHNG_01130 1.91e-197 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IIEKHHNG_01131 4.92e-110 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IIEKHHNG_01132 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
IIEKHHNG_01133 1.51e-313 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IIEKHHNG_01134 3.95e-292 - - - S - - - Fic/DOC family
IIEKHHNG_01135 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
IIEKHHNG_01136 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
IIEKHHNG_01137 2.59e-160 - - - E - - - Ring-cleavage extradiol dioxygenase
IIEKHHNG_01138 7.8e-97 yxaI - - S - - - membrane protein domain
IIEKHHNG_01139 7.67e-256 - - - EGP - - - Major Facilitator Superfamily
IIEKHHNG_01140 1.21e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IIEKHHNG_01141 2.5e-85 - - - S - - - Family of unknown function (DUF5391)
IIEKHHNG_01142 1.58e-187 yxaL - - S - - - PQQ-like domain
IIEKHHNG_01143 0.0 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IIEKHHNG_01144 5.42e-275 yxbF - - K - - - Bacterial regulatory proteins, tetR family
IIEKHHNG_01145 1.01e-254 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
IIEKHHNG_01146 4.12e-255 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_01147 3.72e-132 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIEKHHNG_01148 5.9e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IIEKHHNG_01150 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
IIEKHHNG_01151 4.5e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IIEKHHNG_01152 3.94e-221 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
IIEKHHNG_01153 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IIEKHHNG_01154 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IIEKHHNG_01155 3.45e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IIEKHHNG_01156 5.42e-229 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IIEKHHNG_01157 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IIEKHHNG_01158 4.62e-223 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IIEKHHNG_01159 1.23e-292 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
IIEKHHNG_01160 6.3e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IIEKHHNG_01161 6.24e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
IIEKHHNG_01162 2.68e-192 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IIEKHHNG_01163 1.35e-202 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IIEKHHNG_01164 1.05e-167 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IIEKHHNG_01165 9.21e-166 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 permease
IIEKHHNG_01166 7.54e-211 - - - V ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_01167 1.51e-174 yvrH - - T - - - Transcriptional regulator
IIEKHHNG_01168 0.0 - - - T - - - Histidine kinase
IIEKHHNG_01169 1.09e-157 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIEKHHNG_01170 4.59e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_01171 6.61e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_01172 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IIEKHHNG_01173 4.9e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
IIEKHHNG_01174 1.61e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IIEKHHNG_01175 2.27e-08 - - - L - - - Helix-hairpin-helix motif
IIEKHHNG_01176 6.89e-08 yxeD - - - - - - -
IIEKHHNG_01177 9.43e-34 yxeE - - - - - - -
IIEKHHNG_01180 2.32e-193 yxeH - - S - - - hydrolases of the HAD superfamily
IIEKHHNG_01181 1.12e-217 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IIEKHHNG_01182 1.17e-144 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IIEKHHNG_01183 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IIEKHHNG_01184 1.1e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
IIEKHHNG_01185 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IIEKHHNG_01186 1.32e-222 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IIEKHHNG_01187 3.7e-298 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
IIEKHHNG_01188 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IIEKHHNG_01189 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
IIEKHHNG_01190 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IIEKHHNG_01191 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IIEKHHNG_01193 4.36e-225 - - - L - - - AlwI restriction endonuclease
IIEKHHNG_01194 3.9e-232 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
IIEKHHNG_01195 5.59e-58 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
IIEKHHNG_01196 1.86e-18 - - - S - - - Domain of unknown function (DUF5082)
IIEKHHNG_01197 5.71e-130 - - - L - - - Replication protein
IIEKHHNG_01198 4.69e-39 - - - - - - - -
IIEKHHNG_01200 7.64e-53 - - - K - - - Transcriptional regulator
IIEKHHNG_01203 1.41e-93 yxiE - - T - - - Belongs to the universal stress protein A family
IIEKHHNG_01204 8.44e-208 yxxF - - EG - - - EamA-like transporter family
IIEKHHNG_01205 1.05e-254 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
IIEKHHNG_01206 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IIEKHHNG_01207 1e-279 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
IIEKHHNG_01208 1.91e-183 bglS - - M - - - licheninase activity
IIEKHHNG_01209 1.35e-282 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IIEKHHNG_01210 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IIEKHHNG_01211 2.68e-67 yxiS - - - - - - -
IIEKHHNG_01212 8.8e-125 - - - T - - - Domain of unknown function (DUF4163)
IIEKHHNG_01213 9.51e-267 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IIEKHHNG_01214 1.83e-163 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
IIEKHHNG_01215 6.59e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
IIEKHHNG_01216 6.11e-111 yxjI - - S - - - LURP-one-related
IIEKHHNG_01219 6.94e-302 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
IIEKHHNG_01220 2.28e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IIEKHHNG_01221 2.68e-120 yxkC - - S - - - Domain of unknown function (DUF4352)
IIEKHHNG_01222 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IIEKHHNG_01223 2.63e-208 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
IIEKHHNG_01224 2.62e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IIEKHHNG_01225 8.1e-199 yxkH - - G - - - Polysaccharide deacetylase
IIEKHHNG_01226 3.19e-287 cimH - - C - - - COG3493 Na citrate symporter
IIEKHHNG_01227 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IIEKHHNG_01228 1.12e-241 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
IIEKHHNG_01229 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
IIEKHHNG_01230 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
IIEKHHNG_01231 3.07e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IIEKHHNG_01232 3.43e-77 - - - S - - - COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IIEKHHNG_01233 5.75e-131 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IIEKHHNG_01234 0.00047 - - - T - - - helix_turn_helix, Lux Regulon
IIEKHHNG_01235 7.05e-24 ypdB - - KT ko:K02477,ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
IIEKHHNG_01238 1.81e-127 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IIEKHHNG_01240 8.52e-314 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
IIEKHHNG_01241 2.26e-245 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
IIEKHHNG_01242 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IIEKHHNG_01243 8.82e-266 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
IIEKHHNG_01244 1.58e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IIEKHHNG_01245 1.27e-29 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
IIEKHHNG_01246 1.93e-139 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
IIEKHHNG_01247 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IIEKHHNG_01248 1.41e-302 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIEKHHNG_01249 3.22e-65 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IIEKHHNG_01250 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IIEKHHNG_01251 6.3e-291 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IIEKHHNG_01252 6.17e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
IIEKHHNG_01253 7.58e-213 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IIEKHHNG_01254 1.38e-230 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIEKHHNG_01255 4.69e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIEKHHNG_01256 1.08e-143 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
IIEKHHNG_01257 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
IIEKHHNG_01258 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
IIEKHHNG_01259 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIEKHHNG_01260 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IIEKHHNG_01261 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IIEKHHNG_01262 1.35e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IIEKHHNG_01263 4.21e-287 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IIEKHHNG_01264 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIEKHHNG_01265 2.56e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
IIEKHHNG_01266 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIEKHHNG_01267 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
IIEKHHNG_01268 7.57e-215 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
IIEKHHNG_01269 1.85e-151 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
IIEKHHNG_01270 3.64e-208 gspA - - M - - - General stress
IIEKHHNG_01271 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IIEKHHNG_01272 2.71e-314 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIEKHHNG_01273 1.06e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
IIEKHHNG_01274 5.11e-285 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
IIEKHHNG_01275 9.24e-217 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
IIEKHHNG_01276 1.01e-174 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
IIEKHHNG_01277 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
IIEKHHNG_01278 6.47e-144 ywbG - - M - - - effector of murein hydrolase
IIEKHHNG_01279 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IIEKHHNG_01280 4.83e-202 ywbI - - K - - - Transcriptional regulator
IIEKHHNG_01281 1.02e-172 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IIEKHHNG_01282 5.8e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IIEKHHNG_01283 5.15e-308 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
IIEKHHNG_01284 3.09e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IIEKHHNG_01285 1.58e-168 - - - S - - - Streptomycin biosynthesis protein StrF
IIEKHHNG_01286 7.2e-166 - - - H - - - Methionine biosynthesis protein MetW
IIEKHHNG_01288 6.43e-146 - - - K - - - Bacterial regulatory proteins, tetR family
IIEKHHNG_01289 2e-80 gtcA - - S - - - GtrA-like protein
IIEKHHNG_01290 4.22e-288 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IIEKHHNG_01291 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IIEKHHNG_01292 5.74e-48 ydaS - - S - - - membrane
IIEKHHNG_01293 3.14e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IIEKHHNG_01294 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IIEKHHNG_01295 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IIEKHHNG_01296 6.76e-84 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IIEKHHNG_01297 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
IIEKHHNG_01298 1.24e-99 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
IIEKHHNG_01299 7.63e-271 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
IIEKHHNG_01300 1.14e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
IIEKHHNG_01301 1.34e-235 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIEKHHNG_01302 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IIEKHHNG_01304 4.68e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IIEKHHNG_01305 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IIEKHHNG_01306 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IIEKHHNG_01307 3.52e-26 ywdA - - - - - - -
IIEKHHNG_01308 3.39e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IIEKHHNG_01309 1.32e-74 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
IIEKHHNG_01311 7.67e-85 ywdD - - - - - - -
IIEKHHNG_01313 3.29e-192 ywdF - - S - - - Glycosyltransferase like family 2
IIEKHHNG_01314 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IIEKHHNG_01315 1.06e-60 ywdI - - S - - - Family of unknown function (DUF5327)
IIEKHHNG_01316 5.38e-291 ywdJ - - F - - - Xanthine uracil
IIEKHHNG_01317 2.17e-76 ywdK - - S - - - small membrane protein
IIEKHHNG_01318 6.51e-88 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IIEKHHNG_01319 5.24e-183 spsA - - M - - - Spore Coat
IIEKHHNG_01320 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
IIEKHHNG_01321 3.57e-282 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
IIEKHHNG_01322 6.71e-206 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
IIEKHHNG_01323 7.09e-274 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
IIEKHHNG_01324 7.11e-172 spsF - - M ko:K07257 - ko00000 Spore Coat
IIEKHHNG_01325 5.91e-235 spsG - - M - - - Spore Coat
IIEKHHNG_01326 1.63e-176 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IIEKHHNG_01327 6.14e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IIEKHHNG_01328 4.55e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IIEKHHNG_01329 1.15e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
IIEKHHNG_01330 1.32e-221 bcrA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_01331 1.48e-153 - - - S - - - ABC-2 family transporter protein
IIEKHHNG_01332 2.37e-96 - - - - - - - -
IIEKHHNG_01333 6.09e-161 - - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIEKHHNG_01334 2.04e-203 - - - T - - - Histidine kinase
IIEKHHNG_01335 3.15e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IIEKHHNG_01336 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IIEKHHNG_01337 0.0 rocB - - E - - - arginine degradation protein
IIEKHHNG_01338 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IIEKHHNG_01339 2.43e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
IIEKHHNG_01340 1.11e-283 ywfA - - EGP - - - -transporter
IIEKHHNG_01341 3.85e-144 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IIEKHHNG_01342 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IIEKHHNG_01343 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIEKHHNG_01344 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IIEKHHNG_01345 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IIEKHHNG_01346 2.21e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
IIEKHHNG_01347 2.94e-181 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
IIEKHHNG_01348 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
IIEKHHNG_01349 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
IIEKHHNG_01350 9.79e-213 - - - S - - - Conserved hypothetical protein 698
IIEKHHNG_01351 4.54e-210 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_01352 8.76e-202 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IIEKHHNG_01354 1.51e-234 - - - - - - - -
IIEKHHNG_01357 1.79e-216 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
IIEKHHNG_01358 1.65e-211 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_01359 3.78e-120 - - - S - - - membrane
IIEKHHNG_01360 1.08e-67 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
IIEKHHNG_01361 2.48e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
IIEKHHNG_01362 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
IIEKHHNG_01363 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
IIEKHHNG_01364 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
IIEKHHNG_01365 9.94e-316 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
IIEKHHNG_01366 4.16e-93 ywhA - - K - - - Transcriptional regulator
IIEKHHNG_01367 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
IIEKHHNG_01368 3.84e-153 ywhC - - S - - - Peptidase family M50
IIEKHHNG_01369 1.92e-123 ywhD - - S - - - YwhD family
IIEKHHNG_01370 1.32e-14 - - - - - - - -
IIEKHHNG_01371 1.23e-69 - - - - - - - -
IIEKHHNG_01372 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IIEKHHNG_01373 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IIEKHHNG_01374 1.73e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IIEKHHNG_01376 1.38e-103 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IIEKHHNG_01377 3.01e-294 ywhK - - CO - - - amine dehydrogenase activity
IIEKHHNG_01378 5.82e-307 ywhL - - CO - - - amine dehydrogenase activity
IIEKHHNG_01380 2.21e-94 ywiB - - S - - - protein conserved in bacteria
IIEKHHNG_01381 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
IIEKHHNG_01382 4.27e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IIEKHHNG_01383 5.43e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
IIEKHHNG_01384 5.69e-22 ywiC - - S - - - YwiC-like protein
IIEKHHNG_01385 2.91e-109 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
IIEKHHNG_01386 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IIEKHHNG_01387 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
IIEKHHNG_01388 1.48e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
IIEKHHNG_01389 2.41e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
IIEKHHNG_01390 3.02e-136 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IIEKHHNG_01391 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIEKHHNG_01392 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
IIEKHHNG_01393 1.13e-58 ywjC - - - - - - -
IIEKHHNG_01394 8.09e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IIEKHHNG_01395 6.69e-283 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IIEKHHNG_01396 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
IIEKHHNG_01397 8.4e-76 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IIEKHHNG_01398 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IIEKHHNG_01399 6.67e-120 ywjG - - S - - - Domain of unknown function (DUF2529)
IIEKHHNG_01400 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
IIEKHHNG_01401 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
IIEKHHNG_01402 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IIEKHHNG_01403 5.55e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIEKHHNG_01404 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
IIEKHHNG_01405 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IIEKHHNG_01406 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
IIEKHHNG_01407 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
IIEKHHNG_01408 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IIEKHHNG_01409 2.02e-202 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
IIEKHHNG_01410 8.54e-123 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IIEKHHNG_01411 6.14e-87 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIEKHHNG_01412 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IIEKHHNG_01413 1.4e-202 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IIEKHHNG_01414 1.71e-78 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IIEKHHNG_01415 1.88e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
IIEKHHNG_01416 2.02e-97 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
IIEKHHNG_01417 3.6e-242 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IIEKHHNG_01418 1.36e-118 mntP - - P - - - Probably functions as a manganese efflux pump
IIEKHHNG_01419 1.2e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIEKHHNG_01420 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
IIEKHHNG_01421 3.68e-125 ywlG - - S - - - Belongs to the UPF0340 family
IIEKHHNG_01422 1.99e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IIEKHHNG_01423 6.42e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IIEKHHNG_01424 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
IIEKHHNG_01425 3e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
IIEKHHNG_01426 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIEKHHNG_01427 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IIEKHHNG_01428 2.77e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIEKHHNG_01429 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IIEKHHNG_01430 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IIEKHHNG_01431 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IIEKHHNG_01432 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
IIEKHHNG_01433 4.15e-117 ywmA - - - - - - -
IIEKHHNG_01434 2.25e-45 ywzB - - S - - - membrane
IIEKHHNG_01435 8.35e-175 ywmB - - S - - - TATA-box binding
IIEKHHNG_01436 7.05e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIEKHHNG_01437 4.93e-243 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
IIEKHHNG_01438 2.59e-160 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IIEKHHNG_01439 1.5e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IIEKHHNG_01441 1.06e-185 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IIEKHHNG_01442 3.1e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IIEKHHNG_01443 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IIEKHHNG_01444 3.66e-108 ywmF - - S - - - Peptidase M50
IIEKHHNG_01445 2.01e-16 csbD - - K - - - CsbD-like
IIEKHHNG_01446 2.86e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
IIEKHHNG_01447 1.07e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
IIEKHHNG_01448 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IIEKHHNG_01449 3.61e-87 ywnA - - K - - - Transcriptional regulator
IIEKHHNG_01451 5.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
IIEKHHNG_01452 6.88e-80 ywnC - - S - - - Family of unknown function (DUF5362)
IIEKHHNG_01453 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIEKHHNG_01454 6.01e-89 ywnF - - S - - - Family of unknown function (DUF5392)
IIEKHHNG_01456 2.76e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
IIEKHHNG_01457 2.17e-187 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IIEKHHNG_01458 4.67e-95 ywnJ - - S - - - VanZ like family
IIEKHHNG_01459 1.17e-131 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
IIEKHHNG_01460 1.72e-266 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IIEKHHNG_01461 1.07e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
IIEKHHNG_01462 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
IIEKHHNG_01463 1.13e-132 yjgF - - Q - - - Isochorismatase family
IIEKHHNG_01464 2.31e-311 ywoD - - EGP - - - Major facilitator superfamily
IIEKHHNG_01465 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
IIEKHHNG_01466 4.1e-272 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IIEKHHNG_01467 3.58e-93 ywoH - - K - - - transcriptional
IIEKHHNG_01468 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
IIEKHHNG_01469 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
IIEKHHNG_01470 2e-171 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IIEKHHNG_01471 4.45e-186 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IIEKHHNG_01472 1.34e-257 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
IIEKHHNG_01473 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IIEKHHNG_01474 1.87e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IIEKHHNG_01475 1.52e-89 ywpF - - S - - - YwpF-like protein
IIEKHHNG_01476 4.49e-82 ywpG - - - - - - -
IIEKHHNG_01477 1.47e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
IIEKHHNG_01478 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
IIEKHHNG_01479 1.51e-201 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IIEKHHNG_01480 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IIEKHHNG_01481 0.0 ywqB - - S - - - SWIM zinc finger
IIEKHHNG_01482 1.74e-21 - - - - - - - -
IIEKHHNG_01483 8.29e-151 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
IIEKHHNG_01484 2.12e-155 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IIEKHHNG_01485 5.03e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
IIEKHHNG_01486 8.72e-314 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IIEKHHNG_01487 1.2e-191 ywqG - - S - - - Domain of unknown function (DUF1963)
IIEKHHNG_01490 2.97e-50 ywqI - - S - - - Family of unknown function (DUF5344)
IIEKHHNG_01491 0.0 ywqJ - - S - - - Pre-toxin TG
IIEKHHNG_01492 5.28e-113 - - - - - - - -
IIEKHHNG_01493 1.66e-65 - - - - - - - -
IIEKHHNG_01495 7.58e-123 - - - - - - - -
IIEKHHNG_01496 4.84e-170 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IIEKHHNG_01497 5.92e-203 - - - K - - - Transcriptional regulator
IIEKHHNG_01498 2.58e-121 ywqN - - S - - - NAD(P)H-dependent
IIEKHHNG_01500 2.47e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
IIEKHHNG_01501 2e-130 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
IIEKHHNG_01502 3.53e-110 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IIEKHHNG_01503 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IIEKHHNG_01505 2.33e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IIEKHHNG_01506 6.3e-22 - - - - - - - -
IIEKHHNG_01507 5.34e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
IIEKHHNG_01508 2.49e-183 cotB - - - ko:K06325 - ko00000 -
IIEKHHNG_01509 3.43e-163 ywrJ - - - - - - -
IIEKHHNG_01510 1.04e-306 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IIEKHHNG_01512 5.35e-215 alsR - - K - - - LysR substrate binding domain
IIEKHHNG_01513 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
IIEKHHNG_01514 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
IIEKHHNG_01515 1.75e-123 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
IIEKHHNG_01516 2.39e-115 batE - - T - - - Sh3 type 3 domain protein
IIEKHHNG_01517 1.15e-206 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
IIEKHHNG_01518 4.4e-204 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IIEKHHNG_01519 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IIEKHHNG_01520 1.38e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IIEKHHNG_01521 2.94e-203 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IIEKHHNG_01522 3.66e-229 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
IIEKHHNG_01523 5.06e-260 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
IIEKHHNG_01524 1.03e-245 - - - E - - - Spore germination protein
IIEKHHNG_01525 1.26e-241 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
IIEKHHNG_01526 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
IIEKHHNG_01527 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
IIEKHHNG_01528 1.39e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IIEKHHNG_01529 4.04e-29 ywtC - - - - - - -
IIEKHHNG_01530 6.43e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IIEKHHNG_01531 6.84e-74 yttA - - S - - - Pfam Transposase IS66
IIEKHHNG_01532 6.43e-203 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IIEKHHNG_01533 1.14e-229 ywtF_2 - - K - - - Transcriptional regulator
IIEKHHNG_01534 1.99e-314 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IIEKHHNG_01535 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
IIEKHHNG_01536 8.96e-274 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
IIEKHHNG_01537 1.66e-249 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IIEKHHNG_01538 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IIEKHHNG_01539 1.07e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IIEKHHNG_01540 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IIEKHHNG_01541 2.57e-272 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IIEKHHNG_01542 2.13e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IIEKHHNG_01543 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
IIEKHHNG_01544 0.0 - - - M - - - Glycosyltransferase like family 2
IIEKHHNG_01545 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IIEKHHNG_01546 1.45e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
IIEKHHNG_01547 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IIEKHHNG_01548 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IIEKHHNG_01549 2.86e-267 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IIEKHHNG_01550 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IIEKHHNG_01551 1.86e-64 - - - - - - - -
IIEKHHNG_01552 0.0 lytB - - D - - - Stage II sporulation protein
IIEKHHNG_01553 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IIEKHHNG_01554 4.92e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IIEKHHNG_01555 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IIEKHHNG_01556 4.87e-280 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
IIEKHHNG_01557 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IIEKHHNG_01558 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
IIEKHHNG_01559 3.49e-148 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
IIEKHHNG_01560 4.68e-184 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IIEKHHNG_01561 4.67e-303 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
IIEKHHNG_01562 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IIEKHHNG_01563 1.16e-235 yvhJ - - K - - - Transcriptional regulator
IIEKHHNG_01564 2.94e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
IIEKHHNG_01565 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IIEKHHNG_01566 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIEKHHNG_01567 1.03e-202 degV - - S - - - protein conserved in bacteria
IIEKHHNG_01568 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IIEKHHNG_01569 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
IIEKHHNG_01570 1.01e-99 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
IIEKHHNG_01571 5.47e-98 yvyF - - S - - - flagellar protein
IIEKHHNG_01572 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
IIEKHHNG_01573 3.64e-104 yvyG - - NOU - - - FlgN protein
IIEKHHNG_01574 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
IIEKHHNG_01575 1.4e-207 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
IIEKHHNG_01576 2.8e-108 yviE - - - - - - -
IIEKHHNG_01577 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IIEKHHNG_01578 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IIEKHHNG_01579 6.97e-153 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IIEKHHNG_01580 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IIEKHHNG_01581 5.79e-88 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
IIEKHHNG_01582 4.35e-10 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
IIEKHHNG_01583 1.35e-89 - - - - - - - -
IIEKHHNG_01584 2.28e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IIEKHHNG_01585 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IIEKHHNG_01586 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IIEKHHNG_01587 6.85e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IIEKHHNG_01588 5.11e-59 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IIEKHHNG_01589 8.68e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
IIEKHHNG_01590 2.48e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IIEKHHNG_01591 7.31e-306 ywoF - - P - - - Right handed beta helix region
IIEKHHNG_01592 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IIEKHHNG_01593 2.47e-73 swrA - - S - - - Swarming motility protein
IIEKHHNG_01594 7.21e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IIEKHHNG_01595 9.44e-240 - - - S - - - Psort location CytoplasmicMembrane, score
IIEKHHNG_01597 1.24e-33 - - - Q - - - Thioesterase domain
IIEKHHNG_01598 2.93e-298 yvkA - - P - - - -transporter
IIEKHHNG_01599 2.32e-144 yvkB - - K - - - Transcriptional regulator
IIEKHHNG_01600 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
IIEKHHNG_01601 2.59e-45 csbA - - S - - - protein conserved in bacteria
IIEKHHNG_01602 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IIEKHHNG_01603 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IIEKHHNG_01604 3.29e-43 yvkN - - - - - - -
IIEKHHNG_01605 4.87e-66 yvlA - - - - - - -
IIEKHHNG_01606 5.54e-219 yvlB - - S - - - Putative adhesin
IIEKHHNG_01607 4.01e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
IIEKHHNG_01608 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
IIEKHHNG_01609 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
IIEKHHNG_01610 1.27e-135 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IIEKHHNG_01611 2.13e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
IIEKHHNG_01612 6.1e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IIEKHHNG_01613 3.89e-285 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
IIEKHHNG_01614 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IIEKHHNG_01615 5.27e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IIEKHHNG_01616 9.48e-157 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IIEKHHNG_01617 5.93e-111 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IIEKHHNG_01618 5.06e-178 yvpB - - NU - - - protein conserved in bacteria
IIEKHHNG_01619 1.22e-269 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IIEKHHNG_01620 2.14e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IIEKHHNG_01621 2.72e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IIEKHHNG_01622 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
IIEKHHNG_01623 9.83e-148 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IIEKHHNG_01624 2.67e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IIEKHHNG_01625 8e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IIEKHHNG_01626 9.88e-145 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
IIEKHHNG_01627 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
IIEKHHNG_01628 3.82e-156 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIEKHHNG_01629 1.36e-245 sasA - - T - - - Histidine kinase
IIEKHHNG_01630 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
IIEKHHNG_01631 4.64e-202 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
IIEKHHNG_01632 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IIEKHHNG_01633 2.98e-112 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IIEKHHNG_01634 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
IIEKHHNG_01635 1.28e-225 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
IIEKHHNG_01636 7.32e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
IIEKHHNG_01637 3.23e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
IIEKHHNG_01638 6.65e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
IIEKHHNG_01639 5.54e-105 - - - M - - - Ribonuclease
IIEKHHNG_01640 1.69e-232 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIEKHHNG_01641 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IIEKHHNG_01642 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IIEKHHNG_01643 1.3e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
IIEKHHNG_01644 8.57e-134 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
IIEKHHNG_01645 2.2e-205 yvdE - - K - - - Transcriptional regulator
IIEKHHNG_01646 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
IIEKHHNG_01647 1.49e-261 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
IIEKHHNG_01648 1.1e-279 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
IIEKHHNG_01649 5.29e-178 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
IIEKHHNG_01650 3.08e-137 malA - - S - - - Protein of unknown function (DUF1189)
IIEKHHNG_01651 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
IIEKHHNG_01652 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IIEKHHNG_01653 4.27e-120 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IIEKHHNG_01654 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IIEKHHNG_01655 3.17e-234 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
IIEKHHNG_01656 4.05e-285 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
IIEKHHNG_01657 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IIEKHHNG_01659 1.31e-45 - - - - - - - -
IIEKHHNG_01660 0.0 - - - I - - - Pfam Lipase (class 3)
IIEKHHNG_01661 5e-22 - - - S - - - Protein of unknown function (DUF1433)
IIEKHHNG_01662 2.29e-52 - - - I - - - Pfam Lipase (class 3)
IIEKHHNG_01663 4.22e-51 - - - S - - - Protein of unknown function (DUF1433)
IIEKHHNG_01665 1.01e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
IIEKHHNG_01666 1.9e-119 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIEKHHNG_01667 4.16e-143 yyaS - - S ko:K07149 - ko00000 Membrane
IIEKHHNG_01668 2.32e-126 ywjB - - H - - - RibD C-terminal domain
IIEKHHNG_01669 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
IIEKHHNG_01670 1.99e-99 - - - K ko:K19417 - ko00000,ko03000 transcriptional
IIEKHHNG_01671 1.17e-155 epsA - - M ko:K19420 - ko00000 biosynthesis protein
IIEKHHNG_01672 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IIEKHHNG_01673 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IIEKHHNG_01674 1.23e-277 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
IIEKHHNG_01675 2.74e-206 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
IIEKHHNG_01676 4.98e-272 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IIEKHHNG_01677 3.44e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
IIEKHHNG_01678 6.27e-247 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IIEKHHNG_01679 2.6e-257 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
IIEKHHNG_01680 2.46e-248 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IIEKHHNG_01681 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IIEKHHNG_01682 2.73e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IIEKHHNG_01683 7.66e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IIEKHHNG_01684 1.11e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
IIEKHHNG_01685 2.24e-237 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
IIEKHHNG_01686 4.01e-44 yvfG - - S - - - YvfG protein
IIEKHHNG_01687 2.67e-308 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IIEKHHNG_01688 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IIEKHHNG_01689 3.62e-155 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
IIEKHHNG_01690 3.57e-281 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIEKHHNG_01691 3.55e-172 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IIEKHHNG_01692 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IIEKHHNG_01693 1.44e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IIEKHHNG_01695 2.49e-07 - - - S ko:K07483 - ko00000 leucine-zipper of insertion element IS481
IIEKHHNG_01696 1.37e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
IIEKHHNG_01697 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
IIEKHHNG_01698 1.9e-195 gntR - - K - - - RpiR family transcriptional regulator
IIEKHHNG_01699 1.79e-214 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IIEKHHNG_01700 2.47e-146 - - - S ko:K07149 - ko00000 Membrane
IIEKHHNG_01701 1.51e-232 yhjM - - K - - - Transcriptional regulator
IIEKHHNG_01702 4.71e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IIEKHHNG_01703 6.36e-204 yvbV - - EG - - - EamA-like transporter family
IIEKHHNG_01704 1.24e-199 yvbU - - K - - - Transcriptional regulator
IIEKHHNG_01706 1.08e-242 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIEKHHNG_01707 4.51e-260 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
IIEKHHNG_01708 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IIEKHHNG_01710 3.44e-239 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IIEKHHNG_01711 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IIEKHHNG_01712 6.6e-276 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
IIEKHHNG_01713 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IIEKHHNG_01714 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
IIEKHHNG_01715 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IIEKHHNG_01716 1.63e-301 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
IIEKHHNG_01717 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IIEKHHNG_01718 1.83e-277 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
IIEKHHNG_01719 2.36e-217 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
IIEKHHNG_01720 8.99e-293 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IIEKHHNG_01721 2.95e-187 - - - M - - - Protein involved in cellulose biosynthesis
IIEKHHNG_01722 2.89e-185 - - - C - - - WbqC-like protein family
IIEKHHNG_01723 1.9e-163 - - - S - - - GlcNAc-PI de-N-acetylase
IIEKHHNG_01724 4.84e-229 - - - - - - - -
IIEKHHNG_01725 2.56e-268 - - - EGP - - - Major facilitator Superfamily
IIEKHHNG_01726 1.29e-105 yvbK - - K - - - acetyltransferase
IIEKHHNG_01727 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
IIEKHHNG_01728 7.3e-155 yvbI - - M - - - Membrane
IIEKHHNG_01729 1.88e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
IIEKHHNG_01730 6.82e-128 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IIEKHHNG_01731 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IIEKHHNG_01732 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IIEKHHNG_01733 4.61e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IIEKHHNG_01734 6.21e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IIEKHHNG_01735 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IIEKHHNG_01736 1.66e-267 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IIEKHHNG_01737 3.4e-146 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IIEKHHNG_01738 1.8e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IIEKHHNG_01739 2.09e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IIEKHHNG_01740 1.55e-161 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_01741 1.15e-155 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IIEKHHNG_01742 6.04e-173 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IIEKHHNG_01743 1.34e-158 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
IIEKHHNG_01744 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
IIEKHHNG_01745 2.44e-69 yvaP - - K - - - transcriptional
IIEKHHNG_01746 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
IIEKHHNG_01747 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
IIEKHHNG_01748 1.64e-47 yvzC - - K - - - transcriptional
IIEKHHNG_01749 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
IIEKHHNG_01750 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
IIEKHHNG_01751 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IIEKHHNG_01752 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IIEKHHNG_01754 1.06e-39 - - - S - - - Phage integrase family
IIEKHHNG_01757 1.88e-06 - - - L - - - AAA ATPase domain
IIEKHHNG_01759 1.13e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IIEKHHNG_01760 3.82e-204 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
IIEKHHNG_01761 3.69e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IIEKHHNG_01762 5.65e-166 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IIEKHHNG_01763 2.91e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IIEKHHNG_01764 7.29e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IIEKHHNG_01765 2.36e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IIEKHHNG_01766 8.64e-179 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IIEKHHNG_01767 3.54e-232 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIEKHHNG_01768 3.52e-62 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
IIEKHHNG_01769 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIEKHHNG_01770 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IIEKHHNG_01771 9.62e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IIEKHHNG_01772 2.81e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
IIEKHHNG_01773 1.88e-39 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
IIEKHHNG_01774 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
IIEKHHNG_01775 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IIEKHHNG_01776 1.84e-137 bdbD - - O - - - Thioredoxin
IIEKHHNG_01777 3.05e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
IIEKHHNG_01778 1.1e-189 - - - S - - - Metallo-peptidase family M12
IIEKHHNG_01779 1.3e-138 yvgT - - S - - - membrane
IIEKHHNG_01780 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IIEKHHNG_01781 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IIEKHHNG_01782 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IIEKHHNG_01783 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
IIEKHHNG_01784 1.32e-111 yvgO - - - - - - -
IIEKHHNG_01785 7.23e-200 yvgN - - S - - - reductase
IIEKHHNG_01786 5.2e-255 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IIEKHHNG_01787 1.22e-249 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IIEKHHNG_01788 1.66e-218 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
IIEKHHNG_01789 7.24e-245 - - - T - - - Histidine kinase
IIEKHHNG_01790 4.32e-148 yfiK - - K - - - Regulator
IIEKHHNG_01791 2.33e-126 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
IIEKHHNG_01792 1.95e-178 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
IIEKHHNG_01793 3.88e-211 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
IIEKHHNG_01794 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
IIEKHHNG_01795 4.11e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
IIEKHHNG_01796 1.29e-20 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
IIEKHHNG_01797 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
IIEKHHNG_01798 1.28e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IIEKHHNG_01799 3.29e-238 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIEKHHNG_01800 2.27e-224 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIEKHHNG_01801 1.39e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IIEKHHNG_01802 8.36e-89 yvrL - - S - - - Regulatory protein YrvL
IIEKHHNG_01803 8.91e-295 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IIEKHHNG_01804 1.88e-21 - - - S - - - YvrJ protein family
IIEKHHNG_01805 3.23e-134 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
IIEKHHNG_01806 1.67e-50 - - - - - - - -
IIEKHHNG_01807 7.74e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIEKHHNG_01808 0.0 yvrG - - T - - - Histidine kinase
IIEKHHNG_01809 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
IIEKHHNG_01810 8.63e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IIEKHHNG_01811 1.93e-214 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IIEKHHNG_01812 7.3e-227 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIEKHHNG_01813 3.18e-281 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IIEKHHNG_01814 1.54e-131 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
IIEKHHNG_01815 2.77e-289 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IIEKHHNG_01816 3.14e-66 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
IIEKHHNG_01817 9.74e-134 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IIEKHHNG_01818 1.43e-192 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
IIEKHHNG_01819 2.99e-162 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
IIEKHHNG_01820 3.48e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_01821 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIEKHHNG_01822 2.93e-260 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
IIEKHHNG_01823 1.77e-243 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IIEKHHNG_01824 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IIEKHHNG_01825 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
IIEKHHNG_01826 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IIEKHHNG_01827 1.8e-200 yuxN - - K - - - Transcriptional regulator
IIEKHHNG_01828 2.68e-32 - - - - - - - -
IIEKHHNG_01829 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_01830 3.7e-163 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIEKHHNG_01831 1.26e-303 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IIEKHHNG_01832 2.39e-102 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IIEKHHNG_01833 1.29e-195 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IIEKHHNG_01834 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
IIEKHHNG_01835 7.61e-60 - - - S - - - YusW-like protein
IIEKHHNG_01836 1.29e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IIEKHHNG_01837 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
IIEKHHNG_01838 2.83e-239 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIEKHHNG_01839 4.14e-176 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
IIEKHHNG_01840 2.31e-201 - - - K - - - Transcriptional regulator
IIEKHHNG_01841 4.52e-202 yusT - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
IIEKHHNG_01842 1.81e-169 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IIEKHHNG_01843 1.24e-86 yusQ - - S - - - Tautomerase enzyme
IIEKHHNG_01844 0.0 yusP - - P - - - Major facilitator superfamily
IIEKHHNG_01845 1.31e-89 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
IIEKHHNG_01846 5.21e-71 yusN - - M - - - Coat F domain
IIEKHHNG_01847 3.2e-58 - - - - - - - -
IIEKHHNG_01848 8.5e-212 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IIEKHHNG_01849 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
IIEKHHNG_01850 1.56e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
IIEKHHNG_01851 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IIEKHHNG_01852 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
IIEKHHNG_01853 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IIEKHHNG_01854 1.8e-54 yusG - - S - - - Protein of unknown function (DUF2553)
IIEKHHNG_01855 1.08e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
IIEKHHNG_01856 1.64e-72 yusE - - CO - - - Thioredoxin
IIEKHHNG_01857 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
IIEKHHNG_01858 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IIEKHHNG_01859 1.91e-134 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
IIEKHHNG_01860 9e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
IIEKHHNG_01861 5.13e-84 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IIEKHHNG_01862 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IIEKHHNG_01863 1.23e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
IIEKHHNG_01864 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IIEKHHNG_01865 5.15e-100 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
IIEKHHNG_01866 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
IIEKHHNG_01867 2.94e-200 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IIEKHHNG_01868 6.17e-104 yncE - - S - - - Protein of unknown function (DUF2691)
IIEKHHNG_01870 1.16e-48 - - - - - - - -
IIEKHHNG_01871 2.72e-261 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
IIEKHHNG_01872 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
IIEKHHNG_01874 1.75e-28 - - - S - - - Sporulation delaying protein SdpA
IIEKHHNG_01875 4.36e-94 - - - - - - - -
IIEKHHNG_01877 2.73e-211 - - - K - - - helix_turn_helix, mercury resistance
IIEKHHNG_01878 1.57e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IIEKHHNG_01879 2.12e-312 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
IIEKHHNG_01880 1.68e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IIEKHHNG_01881 8.84e-210 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
IIEKHHNG_01882 2.16e-205 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
IIEKHHNG_01883 4.84e-172 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
IIEKHHNG_01884 4.53e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IIEKHHNG_01885 4.09e-217 bsn - - L - - - Ribonuclease
IIEKHHNG_01886 9.02e-295 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IIEKHHNG_01887 2.32e-299 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IIEKHHNG_01888 4.28e-274 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IIEKHHNG_01889 3.55e-30 - - - - - - - -
IIEKHHNG_01890 2.77e-12 - - - - - - - -
IIEKHHNG_01892 8.78e-18 yqbD - - L - - - Putative phage serine protease XkdF
IIEKHHNG_01893 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
IIEKHHNG_01894 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IIEKHHNG_01895 3.04e-80 - - - S - - - phosphoglycolate phosphatase activity
IIEKHHNG_01896 1.8e-217 yunF - - S - - - Protein of unknown function DUF72
IIEKHHNG_01897 3.01e-186 yunE - - S ko:K07090 - ko00000 membrane transporter protein
IIEKHHNG_01898 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IIEKHHNG_01899 2.75e-167 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
IIEKHHNG_01900 8.24e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
IIEKHHNG_01901 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IIEKHHNG_01902 3.71e-62 yutD - - S - - - protein conserved in bacteria
IIEKHHNG_01903 1.55e-95 yutE - - S - - - Protein of unknown function DUF86
IIEKHHNG_01904 1.38e-178 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IIEKHHNG_01905 1.75e-108 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
IIEKHHNG_01906 1.55e-250 yutH - - S - - - Spore coat protein
IIEKHHNG_01907 8.26e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
IIEKHHNG_01908 5.41e-250 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IIEKHHNG_01909 6.76e-217 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IIEKHHNG_01910 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
IIEKHHNG_01911 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
IIEKHHNG_01912 1.34e-72 yuzD - - S - - - protein conserved in bacteria
IIEKHHNG_01913 8.47e-266 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IIEKHHNG_01914 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
IIEKHHNG_01915 1.49e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IIEKHHNG_01916 2.25e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IIEKHHNG_01917 3.25e-81 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
IIEKHHNG_01918 9.01e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IIEKHHNG_01919 4.15e-122 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
IIEKHHNG_01921 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
IIEKHHNG_01923 6.54e-157 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IIEKHHNG_01924 5.92e-93 - - - CP - - - Membrane
IIEKHHNG_01925 2.32e-39 - - - - - - - -
IIEKHHNG_01926 1.35e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IIEKHHNG_01928 4.19e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
IIEKHHNG_01929 3.42e-300 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IIEKHHNG_01930 2.45e-45 yuiB - - S - - - Putative membrane protein
IIEKHHNG_01931 9.86e-153 yuiC - - S - - - protein conserved in bacteria
IIEKHHNG_01932 8.29e-100 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
IIEKHHNG_01933 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IIEKHHNG_01934 8.19e-276 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
IIEKHHNG_01935 3.73e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
IIEKHHNG_01936 1.13e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
IIEKHHNG_01937 1.72e-209 eSD - - S ko:K07017 - ko00000 Putative esterase
IIEKHHNG_01938 2.03e-170 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IIEKHHNG_01939 3.2e-285 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IIEKHHNG_01940 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
IIEKHHNG_01941 7.94e-220 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
IIEKHHNG_01942 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIEKHHNG_01943 9.15e-45 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
IIEKHHNG_01944 3.06e-171 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
IIEKHHNG_01945 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
IIEKHHNG_01946 1.22e-290 yukF - - QT - - - Transcriptional regulator
IIEKHHNG_01947 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
IIEKHHNG_01948 5.28e-53 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
IIEKHHNG_01949 6.52e-275 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
IIEKHHNG_01950 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IIEKHHNG_01951 0.0 yueB - - S - - - type VII secretion protein EsaA
IIEKHHNG_01952 8.01e-102 yueC - - S - - - Family of unknown function (DUF5383)
IIEKHHNG_01953 2.04e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIEKHHNG_01954 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
IIEKHHNG_01955 2.81e-31 - - - S - - - Protein of unknown function (DUF2642)
IIEKHHNG_01956 2.67e-238 yueF - - S - - - transporter activity
IIEKHHNG_01957 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
IIEKHHNG_01958 5.46e-51 yueH - - S - - - YueH-like protein
IIEKHHNG_01959 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
IIEKHHNG_01960 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
IIEKHHNG_01961 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IIEKHHNG_01962 4.6e-178 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
IIEKHHNG_01963 3.42e-96 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
IIEKHHNG_01964 4.23e-67 yuzC - - - - - - -
IIEKHHNG_01966 2.66e-11 - - - S - - - DegQ (SacQ) family
IIEKHHNG_01967 1.24e-196 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
IIEKHHNG_01969 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_01970 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIEKHHNG_01971 4e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
IIEKHHNG_01972 1.21e-78 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
IIEKHHNG_01973 5.47e-52 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IIEKHHNG_01974 1.23e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IIEKHHNG_01975 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IIEKHHNG_01976 8.54e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IIEKHHNG_01977 6.3e-90 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IIEKHHNG_01978 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IIEKHHNG_01980 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IIEKHHNG_01981 2.72e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IIEKHHNG_01982 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_01983 4.98e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
IIEKHHNG_01984 6.58e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IIEKHHNG_01985 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IIEKHHNG_01986 9.25e-101 yufK - - S - - - Family of unknown function (DUF5366)
IIEKHHNG_01987 5.29e-95 yuxK - - S - - - protein conserved in bacteria
IIEKHHNG_01988 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
IIEKHHNG_01989 3.4e-259 yuxJ - - EGP - - - Major facilitator superfamily
IIEKHHNG_01990 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
IIEKHHNG_01991 2.81e-88 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
IIEKHHNG_01992 2.88e-289 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_01993 1.92e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IIEKHHNG_01994 4.25e-55 yugE - - S - - - Domain of unknown function (DUF1871)
IIEKHHNG_01995 1.64e-199 yugF - - I - - - Hydrolase
IIEKHHNG_01996 3.75e-109 alaR - - K - - - Transcriptional regulator
IIEKHHNG_01997 1.68e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
IIEKHHNG_01998 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IIEKHHNG_01999 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
IIEKHHNG_02000 2.24e-284 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
IIEKHHNG_02001 1.37e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
IIEKHHNG_02002 4.34e-152 ycaC - - Q - - - Isochorismatase family
IIEKHHNG_02003 1.32e-131 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
IIEKHHNG_02004 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
IIEKHHNG_02006 8.53e-95 yugN - - S - - - YugN-like family
IIEKHHNG_02007 4.84e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
IIEKHHNG_02008 4.93e-35 mstX - - S - - - Membrane-integrating protein Mistic
IIEKHHNG_02009 2.16e-23 - - - - - - - -
IIEKHHNG_02010 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
IIEKHHNG_02011 1.63e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IIEKHHNG_02012 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IIEKHHNG_02013 7.72e-98 yugU - - S - - - Uncharacterised protein family UPF0047
IIEKHHNG_02014 2.01e-242 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IIEKHHNG_02015 6.59e-55 - - - - - - - -
IIEKHHNG_02016 2.22e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IIEKHHNG_02017 1.32e-315 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IIEKHHNG_02018 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IIEKHHNG_02019 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IIEKHHNG_02020 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IIEKHHNG_02021 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
IIEKHHNG_02022 1.29e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IIEKHHNG_02023 9.96e-251 yubA - - S - - - transporter activity
IIEKHHNG_02024 6.56e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IIEKHHNG_02026 4.37e-68 yjcN - - - - - - -
IIEKHHNG_02027 3.73e-157 - - - G - - - Cupin
IIEKHHNG_02028 1.07e-280 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IIEKHHNG_02029 2.58e-191 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IIEKHHNG_02030 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IIEKHHNG_02031 9.28e-121 yuaB - - - - - - -
IIEKHHNG_02032 7.09e-125 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
IIEKHHNG_02033 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IIEKHHNG_02034 1.74e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
IIEKHHNG_02035 6.79e-141 - - - S - - - MOSC domain
IIEKHHNG_02036 2.98e-104 yuaE - - S - - - DinB superfamily
IIEKHHNG_02037 5.61e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
IIEKHHNG_02038 1.08e-277 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
IIEKHHNG_02039 6.67e-123 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
IIEKHHNG_02062 1.82e-102 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
IIEKHHNG_02063 3.03e-169 yteA - - T - - - COG1734 DnaK suppressor protein
IIEKHHNG_02064 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IIEKHHNG_02065 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IIEKHHNG_02066 2.52e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IIEKHHNG_02067 7.52e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IIEKHHNG_02068 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IIEKHHNG_02069 2.88e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IIEKHHNG_02070 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
IIEKHHNG_02071 1.06e-234 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IIEKHHNG_02072 4.48e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IIEKHHNG_02073 1.23e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
IIEKHHNG_02074 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IIEKHHNG_02075 8.41e-54 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
IIEKHHNG_02076 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IIEKHHNG_02077 1.26e-100 ytkA - - S - - - YtkA-like
IIEKHHNG_02079 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IIEKHHNG_02080 1.23e-79 ytkC - - S - - - Bacteriophage holin family
IIEKHHNG_02081 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IIEKHHNG_02082 5.66e-169 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IIEKHHNG_02083 3.39e-181 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IIEKHHNG_02084 1.07e-237 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IIEKHHNG_02085 1.84e-188 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IIEKHHNG_02086 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
IIEKHHNG_02087 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IIEKHHNG_02088 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IIEKHHNG_02089 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IIEKHHNG_02090 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IIEKHHNG_02091 4.06e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IIEKHHNG_02092 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
IIEKHHNG_02093 2.02e-271 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
IIEKHHNG_02094 1.49e-184 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
IIEKHHNG_02096 1.26e-136 ytqB - - J - - - Putative rRNA methylase
IIEKHHNG_02097 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
IIEKHHNG_02098 1.43e-52 ytzC - - S - - - Protein of unknown function (DUF2524)
IIEKHHNG_02100 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
IIEKHHNG_02101 4.38e-209 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_02102 4.31e-213 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IIEKHHNG_02103 2.68e-228 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IIEKHHNG_02104 2.02e-206 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
IIEKHHNG_02105 2.12e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_02106 4.75e-288 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IIEKHHNG_02107 9.07e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIEKHHNG_02108 6.12e-222 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
IIEKHHNG_02109 4.63e-174 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_02110 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
IIEKHHNG_02111 1.55e-162 ywaF - - S - - - Integral membrane protein
IIEKHHNG_02112 3.35e-269 yttB - - EGP - - - Major facilitator superfamily
IIEKHHNG_02113 4.59e-175 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IIEKHHNG_02114 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
IIEKHHNG_02115 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
IIEKHHNG_02116 3.51e-68 ytwF - - P - - - Sulfurtransferase
IIEKHHNG_02117 6.9e-111 - - - M - - - Acetyltransferase (GNAT) domain
IIEKHHNG_02118 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
IIEKHHNG_02119 2.88e-184 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IIEKHHNG_02120 2.44e-212 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IIEKHHNG_02121 3.24e-310 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IIEKHHNG_02122 7.81e-239 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_02123 2.14e-36 yteV - - S - - - Sporulation protein Cse60
IIEKHHNG_02124 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
IIEKHHNG_02125 3.73e-299 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
IIEKHHNG_02126 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IIEKHHNG_02127 5.02e-168 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IIEKHHNG_02128 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
IIEKHHNG_02129 2.58e-163 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IIEKHHNG_02130 1.75e-276 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
IIEKHHNG_02131 1.48e-290 pbuO - - S ko:K06901 - ko00000,ko02000 permease
IIEKHHNG_02132 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
IIEKHHNG_02133 6.81e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IIEKHHNG_02134 6.34e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IIEKHHNG_02135 1.47e-216 ytlQ - - - - - - -
IIEKHHNG_02136 1.61e-224 ytlR - - I - - - Diacylglycerol kinase catalytic domain
IIEKHHNG_02137 2.93e-199 ytmP - - M - - - Phosphotransferase
IIEKHHNG_02138 5.51e-60 ytzH - - S - - - YtzH-like protein
IIEKHHNG_02139 1.07e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IIEKHHNG_02140 4.38e-208 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IIEKHHNG_02141 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IIEKHHNG_02142 9.96e-69 ytzB - - S - - - small secreted protein
IIEKHHNG_02143 5.06e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
IIEKHHNG_02144 1.94e-100 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
IIEKHHNG_02145 5.47e-76 ytpP - - CO - - - Thioredoxin
IIEKHHNG_02146 2.4e-190 ytpQ - - S - - - Belongs to the UPF0354 family
IIEKHHNG_02147 2.08e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIEKHHNG_02148 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IIEKHHNG_02149 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
IIEKHHNG_02150 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IIEKHHNG_02151 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
IIEKHHNG_02152 1.19e-57 ytxJ - - O - - - Protein of unknown function (DUF2847)
IIEKHHNG_02153 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IIEKHHNG_02154 1.39e-233 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
IIEKHHNG_02155 5.2e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IIEKHHNG_02156 4.99e-154 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IIEKHHNG_02157 1.94e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
IIEKHHNG_02158 2.06e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
IIEKHHNG_02159 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IIEKHHNG_02160 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IIEKHHNG_02161 5.98e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IIEKHHNG_02162 8.79e-64 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
IIEKHHNG_02163 2.86e-160 ygaZ - - E - - - AzlC protein
IIEKHHNG_02164 9.06e-190 - - - K - - - Transcriptional regulator
IIEKHHNG_02165 1.43e-192 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIEKHHNG_02166 2.39e-176 - - - E - - - GDSL-like Lipase/Acylhydrolase family
IIEKHHNG_02168 1.65e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IIEKHHNG_02170 1.58e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IIEKHHNG_02171 2.3e-23 - - - - - - - -
IIEKHHNG_02173 7.11e-19 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IIEKHHNG_02174 9e-60 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
IIEKHHNG_02176 3.13e-133 yokH - - G - - - SMI1 / KNR4 family
IIEKHHNG_02177 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IIEKHHNG_02178 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IIEKHHNG_02179 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
IIEKHHNG_02180 5.2e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
IIEKHHNG_02181 2.82e-140 yttP - - K - - - Transcriptional regulator
IIEKHHNG_02182 1.99e-194 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IIEKHHNG_02183 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IIEKHHNG_02184 9.7e-309 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IIEKHHNG_02185 1.12e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IIEKHHNG_02186 2.09e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IIEKHHNG_02187 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
IIEKHHNG_02188 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IIEKHHNG_02189 0.0 ytcJ - - S - - - amidohydrolase
IIEKHHNG_02190 2.32e-196 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IIEKHHNG_02191 6.39e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
IIEKHHNG_02192 2.77e-114 yteJ - - S - - - RDD family
IIEKHHNG_02193 1.22e-154 ytfI - - S - - - Protein of unknown function (DUF2953)
IIEKHHNG_02194 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
IIEKHHNG_02195 1.36e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IIEKHHNG_02196 8.37e-232 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
IIEKHHNG_02197 2.33e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIEKHHNG_02198 1.64e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
IIEKHHNG_02199 2.49e-296 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
IIEKHHNG_02200 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
IIEKHHNG_02202 8.38e-184 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIEKHHNG_02203 4.16e-166 ytkL - - S - - - Belongs to the UPF0173 family
IIEKHHNG_02204 7.89e-304 ytoI - - K - - - transcriptional regulator containing CBS domains
IIEKHHNG_02205 3.57e-62 ytpI - - S - - - YtpI-like protein
IIEKHHNG_02206 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
IIEKHHNG_02207 7.04e-32 - - - - - - - -
IIEKHHNG_02208 2.64e-114 ytrI - - - - - - -
IIEKHHNG_02209 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
IIEKHHNG_02210 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
IIEKHHNG_02211 4.23e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IIEKHHNG_02212 8.46e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IIEKHHNG_02213 1.15e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IIEKHHNG_02214 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IIEKHHNG_02215 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
IIEKHHNG_02216 3.42e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
IIEKHHNG_02217 4.05e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
IIEKHHNG_02218 5.65e-96 ytwI - - S - - - membrane
IIEKHHNG_02219 9.5e-84 yjdF3 - - S - - - Protein of unknown function (DUF2992)
IIEKHHNG_02220 1.35e-69 - - - - - - - -
IIEKHHNG_02221 1.42e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IIEKHHNG_02222 1.08e-307 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
IIEKHHNG_02223 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
IIEKHHNG_02224 2.38e-164 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIEKHHNG_02225 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
IIEKHHNG_02226 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IIEKHHNG_02227 1.64e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IIEKHHNG_02228 2.84e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
IIEKHHNG_02229 5.08e-129 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IIEKHHNG_02230 4.54e-205 ytbE - - S - - - reductase
IIEKHHNG_02231 8e-259 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
IIEKHHNG_02232 1.69e-89 ytcD - - K - - - Transcriptional regulator
IIEKHHNG_02233 1.48e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IIEKHHNG_02234 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IIEKHHNG_02235 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IIEKHHNG_02236 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
IIEKHHNG_02237 2.02e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
IIEKHHNG_02238 1.05e-138 ytxB - - S - - - SNARE associated Golgi protein
IIEKHHNG_02239 1.99e-197 ytxC - - S - - - YtxC-like family
IIEKHHNG_02240 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IIEKHHNG_02241 1.2e-192 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
IIEKHHNG_02242 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_02243 1.05e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
IIEKHHNG_02244 1.59e-68 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
IIEKHHNG_02245 3.1e-147 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IIEKHHNG_02246 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IIEKHHNG_02247 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
IIEKHHNG_02248 2.3e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IIEKHHNG_02249 1.34e-56 ysdA - - S - - - Membrane
IIEKHHNG_02250 6.58e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
IIEKHHNG_02251 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
IIEKHHNG_02252 1.11e-237 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IIEKHHNG_02253 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
IIEKHHNG_02254 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
IIEKHHNG_02255 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IIEKHHNG_02256 6.57e-180 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
IIEKHHNG_02257 1.58e-283 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IIEKHHNG_02258 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
IIEKHHNG_02259 4.38e-215 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
IIEKHHNG_02260 1.18e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
IIEKHHNG_02261 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
IIEKHHNG_02262 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
IIEKHHNG_02263 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
IIEKHHNG_02264 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
IIEKHHNG_02265 5.07e-261 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
IIEKHHNG_02266 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
IIEKHHNG_02267 2.2e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIEKHHNG_02268 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IIEKHHNG_02269 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIEKHHNG_02270 3.08e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIEKHHNG_02271 1.47e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IIEKHHNG_02272 6.04e-109 yshB - - S - - - membrane protein, required for colicin V production
IIEKHHNG_02273 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
IIEKHHNG_02274 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IIEKHHNG_02275 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
IIEKHHNG_02276 1.12e-93 ywbB - - S - - - Protein of unknown function (DUF2711)
IIEKHHNG_02277 2.11e-50 ywbB - - S - - - Protein of unknown function (DUF2711)
IIEKHHNG_02278 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IIEKHHNG_02279 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_02280 1.43e-177 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
IIEKHHNG_02281 1.23e-177 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
IIEKHHNG_02282 2.48e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
IIEKHHNG_02283 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
IIEKHHNG_02284 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
IIEKHHNG_02285 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IIEKHHNG_02286 1.74e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IIEKHHNG_02287 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
IIEKHHNG_02288 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
IIEKHHNG_02289 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IIEKHHNG_02290 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IIEKHHNG_02291 8.94e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
IIEKHHNG_02292 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_02293 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
IIEKHHNG_02294 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IIEKHHNG_02295 5.21e-254 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
IIEKHHNG_02296 1.18e-169 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IIEKHHNG_02297 1.59e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IIEKHHNG_02298 9.55e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
IIEKHHNG_02303 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IIEKHHNG_02304 2.06e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IIEKHHNG_02305 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IIEKHHNG_02306 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IIEKHHNG_02307 4.12e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IIEKHHNG_02308 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IIEKHHNG_02309 1.53e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IIEKHHNG_02310 3.33e-241 ysoA - - H - - - Tetratricopeptide repeat
IIEKHHNG_02311 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IIEKHHNG_02312 3.28e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IIEKHHNG_02313 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
IIEKHHNG_02314 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IIEKHHNG_02315 1.79e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
IIEKHHNG_02316 1.6e-113 ysxD - - - - - - -
IIEKHHNG_02317 4.36e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IIEKHHNG_02318 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
IIEKHHNG_02319 5.19e-223 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IIEKHHNG_02320 1.56e-181 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IIEKHHNG_02321 3.43e-236 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
IIEKHHNG_02322 2.68e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IIEKHHNG_02323 3.06e-300 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
IIEKHHNG_02324 1.89e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IIEKHHNG_02325 4.38e-35 - - - - - - - -
IIEKHHNG_02326 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IIEKHHNG_02327 2.28e-308 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
IIEKHHNG_02328 1.27e-171 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IIEKHHNG_02329 8.52e-207 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
IIEKHHNG_02330 2.36e-130 maf - - D ko:K06287 - ko00000 septum formation protein Maf
IIEKHHNG_02331 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
IIEKHHNG_02332 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
IIEKHHNG_02333 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
IIEKHHNG_02334 6.14e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
IIEKHHNG_02335 4.62e-153 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IIEKHHNG_02336 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
IIEKHHNG_02337 1.39e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IIEKHHNG_02338 4.19e-205 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
IIEKHHNG_02339 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
IIEKHHNG_02340 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
IIEKHHNG_02341 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
IIEKHHNG_02342 2.87e-137 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
IIEKHHNG_02343 2.89e-310 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IIEKHHNG_02344 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
IIEKHHNG_02345 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
IIEKHHNG_02346 1.96e-120 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
IIEKHHNG_02347 7.79e-283 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IIEKHHNG_02348 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
IIEKHHNG_02349 1.23e-194 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
IIEKHHNG_02350 4.96e-271 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IIEKHHNG_02351 6.31e-250 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
IIEKHHNG_02352 8.92e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IIEKHHNG_02354 1.21e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
IIEKHHNG_02355 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IIEKHHNG_02356 3.57e-236 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IIEKHHNG_02357 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
IIEKHHNG_02358 5.79e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IIEKHHNG_02359 8.2e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IIEKHHNG_02360 2.09e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
IIEKHHNG_02361 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
IIEKHHNG_02362 4.79e-142 yrbG - - S - - - membrane
IIEKHHNG_02363 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IIEKHHNG_02364 3.45e-68 yrzD - - S - - - Post-transcriptional regulator
IIEKHHNG_02365 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IIEKHHNG_02366 1.26e-111 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IIEKHHNG_02367 2.23e-62 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
IIEKHHNG_02368 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
IIEKHHNG_02369 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IIEKHHNG_02370 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IIEKHHNG_02371 2.86e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IIEKHHNG_02372 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
IIEKHHNG_02375 4.97e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
IIEKHHNG_02376 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IIEKHHNG_02377 9.74e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IIEKHHNG_02378 7.55e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IIEKHHNG_02379 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_02380 4.24e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IIEKHHNG_02381 3.55e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IIEKHHNG_02382 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
IIEKHHNG_02383 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IIEKHHNG_02384 3.14e-103 yrrD - - S - - - protein conserved in bacteria
IIEKHHNG_02385 8.4e-42 yrzR - - - - - - -
IIEKHHNG_02386 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
IIEKHHNG_02387 1.54e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IIEKHHNG_02388 1.13e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IIEKHHNG_02389 3.14e-189 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IIEKHHNG_02390 4.45e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IIEKHHNG_02391 1.15e-237 yrrI - - S - - - AI-2E family transporter
IIEKHHNG_02392 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IIEKHHNG_02393 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
IIEKHHNG_02394 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IIEKHHNG_02395 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
IIEKHHNG_02396 4.67e-258 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IIEKHHNG_02397 2.32e-153 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
IIEKHHNG_02398 3.64e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
IIEKHHNG_02399 1.09e-311 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
IIEKHHNG_02400 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
IIEKHHNG_02401 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IIEKHHNG_02402 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
IIEKHHNG_02403 2.92e-123 yrrS - - S - - - Protein of unknown function (DUF1510)
IIEKHHNG_02404 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
IIEKHHNG_02405 2.83e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
IIEKHHNG_02406 8.02e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IIEKHHNG_02407 1.61e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
IIEKHHNG_02408 2.56e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IIEKHHNG_02409 1.92e-46 yrhC - - S - - - YrhC-like protein
IIEKHHNG_02410 6.49e-104 yrhD - - S - - - Protein of unknown function (DUF1641)
IIEKHHNG_02411 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
IIEKHHNG_02412 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
IIEKHHNG_02413 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
IIEKHHNG_02414 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
IIEKHHNG_02415 9.01e-121 yrhH - - Q - - - methyltransferase
IIEKHHNG_02416 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
IIEKHHNG_02417 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IIEKHHNG_02418 9.68e-273 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IIEKHHNG_02419 2.17e-210 yybE - - K - - - Transcriptional regulator
IIEKHHNG_02420 1.13e-107 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IIEKHHNG_02421 2.81e-232 romA - - S - - - Beta-lactamase superfamily domain
IIEKHHNG_02422 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
IIEKHHNG_02423 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IIEKHHNG_02424 3.44e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IIEKHHNG_02425 2.9e-168 - - - K - - - Helix-turn-helix domain, rpiR family
IIEKHHNG_02426 2.91e-187 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
IIEKHHNG_02427 2.06e-190 supH - - S - - - hydrolase
IIEKHHNG_02428 4.76e-121 - - - S - - - DinB family
IIEKHHNG_02429 8.64e-105 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
IIEKHHNG_02430 1.95e-282 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
IIEKHHNG_02431 4.56e-34 - - - K - - - acetyltransferase
IIEKHHNG_02432 5.27e-126 yqaC - - F - - - adenylate kinase activity
IIEKHHNG_02433 2.4e-132 yrkN - - K - - - Acetyltransferase (GNAT) family
IIEKHHNG_02435 8.05e-278 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
IIEKHHNG_02437 7.69e-159 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
IIEKHHNG_02438 1.27e-306 yrkQ - - T - - - Histidine kinase
IIEKHHNG_02439 1.84e-91 psiE - - S ko:K13256 - ko00000 Belongs to the PsiE family
IIEKHHNG_02440 2.6e-118 - - - K - - - Transcriptional regulator PadR-like family
IIEKHHNG_02441 1.03e-201 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
IIEKHHNG_02443 2.52e-68 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIEKHHNG_02444 1.03e-60 - - - D - - - nuclear chromosome segregation
IIEKHHNG_02445 1.63e-77 yqaQ - - L - - - Transposase
IIEKHHNG_02446 3.43e-77 yjcP - - - - - - -
IIEKHHNG_02447 3.83e-61 - - - S - - - YjcQ protein
IIEKHHNG_02448 4.67e-16 - - - - - - - -
IIEKHHNG_02449 7.78e-91 - - - K - - - MerR family transcriptional regulator
IIEKHHNG_02450 1.04e-174 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Aldo/keto reductase family
IIEKHHNG_02452 1.6e-26 xkdR - - S - - - Protein of unknown function (DUF2577)
IIEKHHNG_02453 1.62e-140 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
IIEKHHNG_02454 5.83e-35 xkdS - - S - - - Protein of unknown function (DUF2634)
IIEKHHNG_02455 1.67e-160 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIEKHHNG_02456 3.28e-279 - - - EGP - - - Transmembrane secretion effector
IIEKHHNG_02457 5.88e-32 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IIEKHHNG_02458 4.93e-138 yqeD - - S - - - SNARE associated Golgi protein
IIEKHHNG_02459 8.09e-181 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
IIEKHHNG_02460 3.99e-176 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
IIEKHHNG_02462 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
IIEKHHNG_02463 3.23e-271 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IIEKHHNG_02464 1.2e-200 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IIEKHHNG_02465 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
IIEKHHNG_02466 2.89e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IIEKHHNG_02467 6.89e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
IIEKHHNG_02468 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IIEKHHNG_02469 5.67e-177 yqeM - - Q - - - Methyltransferase
IIEKHHNG_02470 1.19e-192 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIEKHHNG_02471 2.81e-134 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
IIEKHHNG_02472 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
IIEKHHNG_02473 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
IIEKHHNG_02474 3.84e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
IIEKHHNG_02475 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
IIEKHHNG_02476 2.51e-260 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IIEKHHNG_02477 2.14e-278 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
IIEKHHNG_02478 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
IIEKHHNG_02479 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IIEKHHNG_02480 3.95e-274 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
IIEKHHNG_02481 2.73e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IIEKHHNG_02482 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IIEKHHNG_02483 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
IIEKHHNG_02484 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IIEKHHNG_02485 1.09e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
IIEKHHNG_02486 1.01e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IIEKHHNG_02487 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
IIEKHHNG_02488 1.37e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
IIEKHHNG_02489 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
IIEKHHNG_02490 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
IIEKHHNG_02491 1.28e-293 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
IIEKHHNG_02492 4.78e-177 yqfA - - S - - - UPF0365 protein
IIEKHHNG_02493 1.52e-77 yqfB - - - - - - -
IIEKHHNG_02494 3.57e-61 yqfC - - S - - - sporulation protein YqfC
IIEKHHNG_02495 3.72e-282 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
IIEKHHNG_02496 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
IIEKHHNG_02497 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
IIEKHHNG_02498 4.13e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IIEKHHNG_02499 6.41e-84 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
IIEKHHNG_02500 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IIEKHHNG_02501 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IIEKHHNG_02502 6e-24 - - - S - - - YqzL-like protein
IIEKHHNG_02503 8.73e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
IIEKHHNG_02504 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
IIEKHHNG_02505 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
IIEKHHNG_02506 5.89e-145 ccpN - - K - - - CBS domain
IIEKHHNG_02507 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IIEKHHNG_02508 5.52e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
IIEKHHNG_02509 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IIEKHHNG_02510 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IIEKHHNG_02511 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IIEKHHNG_02512 1.72e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
IIEKHHNG_02513 6.25e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IIEKHHNG_02514 1.18e-224 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IIEKHHNG_02515 1.77e-78 yqfQ - - S - - - YqfQ-like protein
IIEKHHNG_02516 2.8e-313 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IIEKHHNG_02517 9.96e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IIEKHHNG_02518 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
IIEKHHNG_02519 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IIEKHHNG_02520 1.3e-99 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
IIEKHHNG_02521 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
IIEKHHNG_02522 3.34e-80 yqfX - - S - - - membrane
IIEKHHNG_02523 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IIEKHHNG_02524 8.76e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
IIEKHHNG_02525 1.08e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
IIEKHHNG_02526 1.12e-98 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
IIEKHHNG_02527 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
IIEKHHNG_02528 5.56e-288 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
IIEKHHNG_02529 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
IIEKHHNG_02530 2.72e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
IIEKHHNG_02531 1.75e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
IIEKHHNG_02532 5.88e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
IIEKHHNG_02533 5.62e-184 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIEKHHNG_02534 5.46e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIEKHHNG_02535 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IIEKHHNG_02536 3.42e-68 yqzD - - - - - - -
IIEKHHNG_02537 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IIEKHHNG_02538 8.62e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IIEKHHNG_02539 5.38e-11 yqgO - - - - - - -
IIEKHHNG_02540 3.61e-276 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IIEKHHNG_02541 9.1e-39 yqgQ - - S - - - Protein conserved in bacteria
IIEKHHNG_02542 7.14e-229 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
IIEKHHNG_02543 4.66e-280 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
IIEKHHNG_02544 8.94e-255 yqgU - - - - - - -
IIEKHHNG_02545 2.99e-65 dglA - - S - - - Thiamine-binding protein
IIEKHHNG_02546 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
IIEKHHNG_02547 3.45e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
IIEKHHNG_02548 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
IIEKHHNG_02549 1.91e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
IIEKHHNG_02551 8.33e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IIEKHHNG_02552 6.23e-303 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IIEKHHNG_02553 2.62e-238 yqxL - - P - - - Mg2 transporter protein
IIEKHHNG_02554 3.84e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IIEKHHNG_02555 9.79e-235 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
IIEKHHNG_02556 4.46e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
IIEKHHNG_02557 2.27e-93 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
IIEKHHNG_02558 3.14e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
IIEKHHNG_02559 2.66e-99 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
IIEKHHNG_02560 2.62e-78 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
IIEKHHNG_02561 8.16e-36 yqzE - - S - - - YqzE-like protein
IIEKHHNG_02562 2.8e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
IIEKHHNG_02563 1.28e-153 yqxM - - - ko:K19433 - ko00000 -
IIEKHHNG_02564 3.13e-101 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
IIEKHHNG_02565 1.82e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
IIEKHHNG_02566 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
IIEKHHNG_02567 2.71e-31 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
IIEKHHNG_02568 8.78e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
IIEKHHNG_02569 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IIEKHHNG_02570 4.04e-265 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
IIEKHHNG_02571 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IIEKHHNG_02572 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IIEKHHNG_02573 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
IIEKHHNG_02574 1.58e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IIEKHHNG_02575 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IIEKHHNG_02576 7e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IIEKHHNG_02577 7.65e-83 yqhP - - - - - - -
IIEKHHNG_02578 7.33e-221 yqhQ - - S - - - Protein of unknown function (DUF1385)
IIEKHHNG_02579 9.4e-117 yqhR - - S - - - Conserved membrane protein YqhR
IIEKHHNG_02580 2.11e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IIEKHHNG_02581 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IIEKHHNG_02582 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
IIEKHHNG_02583 1.27e-220 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
IIEKHHNG_02584 6.93e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
IIEKHHNG_02585 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
IIEKHHNG_02586 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
IIEKHHNG_02587 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
IIEKHHNG_02588 4.27e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
IIEKHHNG_02589 2.35e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
IIEKHHNG_02590 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
IIEKHHNG_02591 4.67e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IIEKHHNG_02592 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IIEKHHNG_02593 1.36e-87 yqhY - - S - - - protein conserved in bacteria
IIEKHHNG_02594 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IIEKHHNG_02595 8.75e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IIEKHHNG_02596 8.28e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIEKHHNG_02597 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIEKHHNG_02598 9.49e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IIEKHHNG_02599 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IIEKHHNG_02600 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
IIEKHHNG_02601 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
IIEKHHNG_02602 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
IIEKHHNG_02603 8.85e-304 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
IIEKHHNG_02604 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IIEKHHNG_02605 2.48e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IIEKHHNG_02608 2.28e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IIEKHHNG_02610 1.15e-145 - - - K - - - Protein of unknown function (DUF1232)
IIEKHHNG_02611 1.96e-131 - - - P - - - Probably functions as a manganese efflux pump
IIEKHHNG_02613 1.39e-136 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
IIEKHHNG_02614 1.1e-174 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IIEKHHNG_02615 2.78e-272 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IIEKHHNG_02616 4.16e-198 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
IIEKHHNG_02617 2.06e-259 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
IIEKHHNG_02618 2.52e-263 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IIEKHHNG_02619 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
IIEKHHNG_02620 2.32e-204 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IIEKHHNG_02621 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
IIEKHHNG_02622 0.0 bkdR - - KT - - - Transcriptional regulator
IIEKHHNG_02623 1.67e-195 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
IIEKHHNG_02624 2.61e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IIEKHHNG_02625 3.45e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
IIEKHHNG_02626 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IIEKHHNG_02627 4.56e-221 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IIEKHHNG_02628 9.83e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IIEKHHNG_02629 1.78e-284 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IIEKHHNG_02630 4.77e-216 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IIEKHHNG_02631 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
IIEKHHNG_02632 3.23e-172 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IIEKHHNG_02633 4.25e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IIEKHHNG_02634 2.89e-163 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IIEKHHNG_02635 4.58e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
IIEKHHNG_02636 3.45e-85 yqjB - - S - - - protein conserved in bacteria
IIEKHHNG_02638 1.33e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
IIEKHHNG_02639 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IIEKHHNG_02640 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
IIEKHHNG_02641 1.68e-190 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIEKHHNG_02642 1.3e-34 yqzJ - - - - - - -
IIEKHHNG_02643 1.92e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIEKHHNG_02644 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IIEKHHNG_02645 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IIEKHHNG_02646 3.37e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IIEKHHNG_02647 1.29e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IIEKHHNG_02648 7.32e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IIEKHHNG_02649 6.43e-66 - - - S - - - GlpM protein
IIEKHHNG_02650 1.42e-196 - - - K - - - LysR substrate binding domain
IIEKHHNG_02651 4.32e-122 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IIEKHHNG_02652 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IIEKHHNG_02655 1.85e-312 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IIEKHHNG_02656 7.97e-168 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IIEKHHNG_02657 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IIEKHHNG_02658 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IIEKHHNG_02659 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IIEKHHNG_02660 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IIEKHHNG_02661 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IIEKHHNG_02662 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IIEKHHNG_02663 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IIEKHHNG_02664 1.9e-279 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IIEKHHNG_02665 5.31e-304 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
IIEKHHNG_02666 1.38e-174 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
IIEKHHNG_02667 1.95e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIEKHHNG_02668 6.83e-224 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IIEKHHNG_02669 2.39e-180 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IIEKHHNG_02670 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
IIEKHHNG_02671 2.58e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
IIEKHHNG_02672 7.67e-96 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIEKHHNG_02674 2.91e-238 yueF - - S - - - transporter activity
IIEKHHNG_02676 9.19e-76 - - - S - - - YolD-like protein
IIEKHHNG_02677 7.74e-298 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIEKHHNG_02678 4.67e-114 yqjY - - K ko:K06977 - ko00000 acetyltransferase
IIEKHHNG_02679 1.71e-80 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
IIEKHHNG_02680 1.76e-224 yqkA - - K - - - GrpB protein
IIEKHHNG_02681 2.2e-79 yqkB - - S - - - Belongs to the HesB IscA family
IIEKHHNG_02682 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
IIEKHHNG_02683 2.27e-223 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IIEKHHNG_02684 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
IIEKHHNG_02685 1.08e-216 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
IIEKHHNG_02686 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
IIEKHHNG_02687 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
IIEKHHNG_02688 6.89e-279 yqxK - - L - - - DNA helicase
IIEKHHNG_02689 1.34e-74 ansR - - K - - - Transcriptional regulator
IIEKHHNG_02690 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
IIEKHHNG_02691 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
IIEKHHNG_02692 2.4e-311 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IIEKHHNG_02693 4.12e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IIEKHHNG_02694 3.39e-31 - - - - - - - -
IIEKHHNG_02695 7.07e-40 yqkK - - - - - - -
IIEKHHNG_02696 3.53e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IIEKHHNG_02697 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
IIEKHHNG_02698 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
IIEKHHNG_02699 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
IIEKHHNG_02700 4.97e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
IIEKHHNG_02701 1.1e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IIEKHHNG_02702 1.43e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IIEKHHNG_02703 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
IIEKHHNG_02704 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IIEKHHNG_02705 7.94e-173 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIEKHHNG_02706 3.86e-142 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
IIEKHHNG_02707 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
IIEKHHNG_02708 8.19e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
IIEKHHNG_02709 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
IIEKHHNG_02710 5.32e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
IIEKHHNG_02711 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
IIEKHHNG_02712 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IIEKHHNG_02713 2.11e-197 ypuA - - S - - - Secreted protein
IIEKHHNG_02714 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IIEKHHNG_02715 1.42e-107 ccdC1 - - O - - - Protein of unknown function (DUF1453)
IIEKHHNG_02716 6.56e-131 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IIEKHHNG_02717 4.92e-71 ypuD - - - - - - -
IIEKHHNG_02718 1.08e-267 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IIEKHHNG_02719 3.97e-144 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
IIEKHHNG_02720 1.8e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IIEKHHNG_02721 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IIEKHHNG_02722 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIEKHHNG_02723 4.51e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
IIEKHHNG_02725 2.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IIEKHHNG_02726 2.73e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IIEKHHNG_02727 6.14e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
IIEKHHNG_02728 1.62e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IIEKHHNG_02729 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
IIEKHHNG_02730 8.99e-116 spmB - - S ko:K06374 - ko00000 Spore maturation protein
IIEKHHNG_02731 1.49e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IIEKHHNG_02732 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IIEKHHNG_02733 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
IIEKHHNG_02734 4.39e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IIEKHHNG_02735 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIEKHHNG_02736 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_02737 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IIEKHHNG_02738 5.62e-254 rsiX - - - - - - -
IIEKHHNG_02739 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIEKHHNG_02740 2.16e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IIEKHHNG_02741 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
IIEKHHNG_02742 7.41e-254 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
IIEKHHNG_02743 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IIEKHHNG_02744 1.09e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
IIEKHHNG_02745 1.5e-132 ypbE - - M - - - Lysin motif
IIEKHHNG_02746 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
IIEKHHNG_02747 1.15e-189 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
IIEKHHNG_02748 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IIEKHHNG_02749 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IIEKHHNG_02750 1.85e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
IIEKHHNG_02751 7.48e-155 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
IIEKHHNG_02752 1.92e-204 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
IIEKHHNG_02753 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
IIEKHHNG_02754 3.83e-76 ypfA - - M - - - Flagellar protein YcgR
IIEKHHNG_02755 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
IIEKHHNG_02756 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
IIEKHHNG_02757 5.73e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
IIEKHHNG_02758 1.98e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IIEKHHNG_02759 1.87e-12 - - - S - - - YpzI-like protein
IIEKHHNG_02760 6.19e-136 yphA - - - - - - -
IIEKHHNG_02761 9.53e-317 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
IIEKHHNG_02762 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
IIEKHHNG_02763 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
IIEKHHNG_02764 3.4e-173 yphF - - - - - - -
IIEKHHNG_02765 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IIEKHHNG_02766 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IIEKHHNG_02767 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
IIEKHHNG_02768 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IIEKHHNG_02769 3.96e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IIEKHHNG_02770 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IIEKHHNG_02771 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IIEKHHNG_02772 8.53e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IIEKHHNG_02773 3.54e-181 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
IIEKHHNG_02774 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IIEKHHNG_02775 7.47e-259 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IIEKHHNG_02776 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IIEKHHNG_02777 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IIEKHHNG_02778 2.37e-211 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IIEKHHNG_02779 2.46e-169 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
IIEKHHNG_02780 2.05e-147 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
IIEKHHNG_02781 1.42e-289 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IIEKHHNG_02782 7.71e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IIEKHHNG_02783 7.15e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IIEKHHNG_02784 1.24e-260 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
IIEKHHNG_02785 3.46e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IIEKHHNG_02786 1.76e-297 ypiA - - S - - - COG0457 FOG TPR repeat
IIEKHHNG_02787 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
IIEKHHNG_02788 3.34e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
IIEKHHNG_02789 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
IIEKHHNG_02790 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
IIEKHHNG_02791 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
IIEKHHNG_02792 7.24e-134 ypjA - - S - - - membrane
IIEKHHNG_02793 2.05e-182 ypjB - - S - - - sporulation protein
IIEKHHNG_02794 1.97e-55 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IIEKHHNG_02795 5.09e-212 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IIEKHHNG_02796 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IIEKHHNG_02797 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
IIEKHHNG_02798 3.98e-188 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IIEKHHNG_02799 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
IIEKHHNG_02800 7.44e-169 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
IIEKHHNG_02801 2.98e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
IIEKHHNG_02802 3.99e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IIEKHHNG_02803 7.73e-231 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IIEKHHNG_02804 1.14e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IIEKHHNG_02805 1.99e-202 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IIEKHHNG_02806 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IIEKHHNG_02807 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
IIEKHHNG_02808 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
IIEKHHNG_02809 2.27e-103 ypmB - - S - - - protein conserved in bacteria
IIEKHHNG_02810 1.46e-283 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IIEKHHNG_02811 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
IIEKHHNG_02812 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
IIEKHHNG_02813 1.02e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IIEKHHNG_02814 1.04e-118 ypoC - - - - - - -
IIEKHHNG_02815 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IIEKHHNG_02816 8.84e-146 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IIEKHHNG_02817 4.72e-238 yppC - - S - - - Protein of unknown function (DUF2515)
IIEKHHNG_02818 0.000542 - - - - ko:K06430 - ko00000 -
IIEKHHNG_02822 1.85e-74 yppG - - S - - - YppG-like protein
IIEKHHNG_02823 1.85e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IIEKHHNG_02824 1.21e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
IIEKHHNG_02825 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IIEKHHNG_02826 1.99e-302 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
IIEKHHNG_02828 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
IIEKHHNG_02829 1.33e-128 ypsA - - S - - - Belongs to the UPF0398 family
IIEKHHNG_02830 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IIEKHHNG_02831 5.46e-275 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
IIEKHHNG_02832 6.91e-31 - - - S - - - YpzG-like protein
IIEKHHNG_02834 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
IIEKHHNG_02835 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IIEKHHNG_02836 4.72e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IIEKHHNG_02837 2.4e-296 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
IIEKHHNG_02838 1.05e-05 - - - - - - - -
IIEKHHNG_02839 3.79e-131 yrdC - - Q - - - Isochorismatase family
IIEKHHNG_02840 1.21e-08 - - - S - - - Bacillus cereus group antimicrobial protein
IIEKHHNG_02841 3.81e-67 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
IIEKHHNG_02842 2.52e-136 - - - J - - - Acetyltransferase (GNAT) domain
IIEKHHNG_02843 5.13e-268 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
IIEKHHNG_02844 2.09e-116 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
IIEKHHNG_02845 0.0 ypbR - - S - - - Dynamin family
IIEKHHNG_02846 8.23e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
IIEKHHNG_02847 2.44e-10 - - - - - - - -
IIEKHHNG_02848 3.33e-210 ypcP - - L - - - 5'3' exonuclease
IIEKHHNG_02850 7.37e-90 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
IIEKHHNG_02851 2.79e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IIEKHHNG_02852 2.06e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
IIEKHHNG_02853 6.59e-40 ypeQ - - S - - - Zinc-finger
IIEKHHNG_02854 9.27e-49 - - - S - - - Protein of unknown function (DUF2564)
IIEKHHNG_02855 5.19e-17 degR - - - - - - -
IIEKHHNG_02856 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
IIEKHHNG_02857 1.49e-274 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IIEKHHNG_02858 2.3e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IIEKHHNG_02859 9.26e-112 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
IIEKHHNG_02860 7.66e-127 yagB - - S ko:K06950 - ko00000 phosphohydrolase
IIEKHHNG_02861 5.44e-202 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
IIEKHHNG_02862 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
IIEKHHNG_02863 4.8e-99 yphP - - S - - - Belongs to the UPF0403 family
IIEKHHNG_02864 8.22e-171 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
IIEKHHNG_02865 6.48e-148 ypjP - - S - - - YpjP-like protein
IIEKHHNG_02866 6.22e-204 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IIEKHHNG_02867 6.07e-117 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IIEKHHNG_02868 1.35e-147 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IIEKHHNG_02869 1.5e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
IIEKHHNG_02870 5.8e-224 yplP - - K - - - Transcriptional regulator
IIEKHHNG_02871 1.42e-307 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IIEKHHNG_02872 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
IIEKHHNG_02873 2.43e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IIEKHHNG_02874 6.09e-175 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
IIEKHHNG_02875 5.59e-126 ypmS - - S - - - protein conserved in bacteria
IIEKHHNG_02876 3.35e-89 ypoP - - K - - - transcriptional
IIEKHHNG_02877 2.82e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIEKHHNG_02878 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
IIEKHHNG_02879 3.43e-134 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IIEKHHNG_02880 0.0 yokA - - L - - - Recombinase
IIEKHHNG_02881 4.29e-109 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
IIEKHHNG_02882 4.26e-109 - - - G - - - SMI1-KNR4 cell-wall
IIEKHHNG_02883 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IIEKHHNG_02884 2.6e-66 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IIEKHHNG_02886 3.41e-216 - - - S - - - amine dehydrogenase activity
IIEKHHNG_02888 6.38e-259 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IIEKHHNG_02889 1.24e-50 yoqH - - M - - - LysM domain
IIEKHHNG_02894 4.14e-94 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IIEKHHNG_02895 6.87e-277 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
IIEKHHNG_02896 1.88e-223 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
IIEKHHNG_02897 3.12e-90 cgeA - - - ko:K06319 - ko00000 -
IIEKHHNG_02898 1.64e-62 cgeC - - - ko:K06321 - ko00000 -
IIEKHHNG_02899 8.84e-316 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
IIEKHHNG_02900 5.71e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
IIEKHHNG_02902 1.19e-83 - - - L - - - Bacterial transcription activator, effector binding domain
IIEKHHNG_02903 1.69e-312 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IIEKHHNG_02904 1.19e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IIEKHHNG_02905 4.64e-160 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IIEKHHNG_02906 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
IIEKHHNG_02907 9.87e-204 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
IIEKHHNG_02908 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
IIEKHHNG_02909 8.13e-62 yokU - - S - - - YokU-like protein, putative antitoxin
IIEKHHNG_02910 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
IIEKHHNG_02911 1.9e-161 yodN - - - - - - -
IIEKHHNG_02913 9.77e-34 yozD - - S - - - YozD-like protein
IIEKHHNG_02914 5.88e-131 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
IIEKHHNG_02915 1.16e-72 yodL - - S - - - YodL-like
IIEKHHNG_02917 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
IIEKHHNG_02918 7.76e-193 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
IIEKHHNG_02919 6.87e-50 yodI - - - - - - -
IIEKHHNG_02920 6.12e-166 yodH - - Q - - - Methyltransferase
IIEKHHNG_02921 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IIEKHHNG_02922 5.86e-168 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_02923 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IIEKHHNG_02924 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
IIEKHHNG_02925 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IIEKHHNG_02926 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
IIEKHHNG_02927 1.09e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IIEKHHNG_02928 2.43e-140 yahD - - S ko:K06999 - ko00000 Carboxylesterase
IIEKHHNG_02929 1.35e-138 yodC - - C - - - nitroreductase
IIEKHHNG_02930 1.2e-74 yodB - - K - - - transcriptional
IIEKHHNG_02931 2.74e-92 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
IIEKHHNG_02932 1.5e-88 iolK - - S - - - tautomerase
IIEKHHNG_02934 4.87e-106 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
IIEKHHNG_02935 4.91e-209 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
IIEKHHNG_02936 5.2e-31 - - - - - - - -
IIEKHHNG_02937 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
IIEKHHNG_02938 1.57e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
IIEKHHNG_02939 1.68e-192 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IIEKHHNG_02940 2.39e-310 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
IIEKHHNG_02942 4.5e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IIEKHHNG_02943 1.13e-276 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
IIEKHHNG_02944 3.47e-287 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IIEKHHNG_02945 6.26e-143 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IIEKHHNG_02946 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
IIEKHHNG_02947 0.0 yojO - - P - - - Von Willebrand factor
IIEKHHNG_02948 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IIEKHHNG_02949 7.41e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IIEKHHNG_02950 1.98e-179 - - - S - - - Metallo-beta-lactamase superfamily
IIEKHHNG_02951 2.82e-214 yocS - - S ko:K03453 - ko00000 -transporter
IIEKHHNG_02952 4.17e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IIEKHHNG_02953 8.22e-213 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
IIEKHHNG_02954 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
IIEKHHNG_02955 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IIEKHHNG_02956 1.11e-41 yozC - - - - - - -
IIEKHHNG_02958 5.32e-75 yozO - - S - - - Bacterial PH domain
IIEKHHNG_02959 6.36e-50 yocN - - - - - - -
IIEKHHNG_02960 1.87e-57 yozN - - - - - - -
IIEKHHNG_02961 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IIEKHHNG_02962 4.98e-13 yocN - - - - - - -
IIEKHHNG_02963 2.71e-13 yocL - - - - - - -
IIEKHHNG_02964 4.5e-79 yocK - - T - - - general stress protein
IIEKHHNG_02966 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IIEKHHNG_02967 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IIEKHHNG_02968 9.79e-168 yocH - - M - - - COG1388 FOG LysM repeat
IIEKHHNG_02970 3.72e-238 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
IIEKHHNG_02971 2.27e-123 yocC - - - - - - -
IIEKHHNG_02972 4.8e-179 - - - J - - - Protein required for attachment to host cells
IIEKHHNG_02973 8.99e-116 yozB - - S ko:K08976 - ko00000 membrane
IIEKHHNG_02974 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IIEKHHNG_02975 6.33e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
IIEKHHNG_02976 1.57e-118 yobW - - - - - - -
IIEKHHNG_02977 1.98e-174 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IIEKHHNG_02978 8.84e-121 yobS - - K - - - Transcriptional regulator
IIEKHHNG_02979 9.78e-169 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
IIEKHHNG_02980 1.05e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
IIEKHHNG_02981 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IIEKHHNG_02982 3.25e-72 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IIEKHHNG_02983 5.5e-56 - - - - - - - -
IIEKHHNG_02984 1.63e-128 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IIEKHHNG_02986 2.99e-22 yoaF - - - - - - -
IIEKHHNG_02987 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IIEKHHNG_02988 4.74e-243 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIEKHHNG_02989 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
IIEKHHNG_02990 1.1e-261 yoaB - - EGP - - - the major facilitator superfamily
IIEKHHNG_02991 2.12e-176 yoxB - - - - - - -
IIEKHHNG_02992 3.03e-50 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IIEKHHNG_02993 1.73e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IIEKHHNG_02994 8.13e-82 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IIEKHHNG_02995 3.42e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIEKHHNG_02996 2.82e-259 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IIEKHHNG_02997 7.8e-207 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_02998 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
IIEKHHNG_02999 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IIEKHHNG_03000 1.77e-239 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IIEKHHNG_03001 2.6e-199 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_03002 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IIEKHHNG_03003 3.29e-67 - - - K - - - Helix-turn-helix domain
IIEKHHNG_03004 1.95e-255 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
IIEKHHNG_03005 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IIEKHHNG_03006 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
IIEKHHNG_03007 3.97e-125 - - - L - - - Integrase
IIEKHHNG_03009 2.13e-124 yoeB - - S - - - IseA DL-endopeptidase inhibitor
IIEKHHNG_03010 7.44e-312 yoeA - - V - - - MATE efflux family protein
IIEKHHNG_03011 1.16e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
IIEKHHNG_03012 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IIEKHHNG_03015 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IIEKHHNG_03016 1.64e-236 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
IIEKHHNG_03017 1.7e-111 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
IIEKHHNG_03018 1.04e-212 ydhU - - P ko:K07217 - ko00000 Catalase
IIEKHHNG_03019 0.0 ybeC - - E - - - amino acid
IIEKHHNG_03020 3.63e-136 yvdT_1 - - K - - - Transcriptional regulator
IIEKHHNG_03021 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IIEKHHNG_03022 1.73e-64 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
IIEKHHNG_03023 1.23e-276 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
IIEKHHNG_03024 1.55e-152 - - - K ko:K05799 - ko00000,ko03000 FCD
IIEKHHNG_03025 7.17e-172 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
IIEKHHNG_03026 1.29e-246 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
IIEKHHNG_03027 2.49e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
IIEKHHNG_03029 0.0 pbpE - - V - - - Beta-lactamase
IIEKHHNG_03032 1.94e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IIEKHHNG_03033 2.67e-153 ydhC - - K - - - FCD
IIEKHHNG_03034 9.74e-209 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Isocitrate/isopropylmalate dehydrogenase
IIEKHHNG_03035 1.34e-187 - - - Q - - - ubiE/COQ5 methyltransferase family
IIEKHHNG_03036 1.35e-146 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
IIEKHHNG_03037 2.1e-190 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IIEKHHNG_03038 6.89e-192 bltR - - K - - - helix_turn_helix, mercury resistance
IIEKHHNG_03039 5.09e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
IIEKHHNG_03040 3.66e-157 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
IIEKHHNG_03041 7.49e-199 - - - K - - - Helix-turn-helix XRE-family like proteins
IIEKHHNG_03042 3.76e-286 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IIEKHHNG_03043 1.59e-267 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
IIEKHHNG_03044 1.08e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
IIEKHHNG_03045 4.59e-189 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IIEKHHNG_03046 7.5e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
IIEKHHNG_03047 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
IIEKHHNG_03048 3.41e-171 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
IIEKHHNG_03049 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
IIEKHHNG_03050 3.28e-141 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIEKHHNG_03051 1.91e-272 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_03052 1.71e-49 yraG - - - ko:K06440 - ko00000 -
IIEKHHNG_03053 3.35e-84 yraF - - M - - - Spore coat protein
IIEKHHNG_03054 3.04e-282 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IIEKHHNG_03055 1.19e-33 yraE - - - ko:K06440 - ko00000 -
IIEKHHNG_03056 5.09e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
IIEKHHNG_03057 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIEKHHNG_03058 2.5e-200 ydeK - - EG - - - -transporter
IIEKHHNG_03059 1.2e-132 ydeS - - K - - - Transcriptional regulator
IIEKHHNG_03060 3.57e-249 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
IIEKHHNG_03062 3.59e-147 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
IIEKHHNG_03063 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
IIEKHHNG_03064 5.68e-281 nhaC_1 - - C - - - antiporter
IIEKHHNG_03065 4.93e-85 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
IIEKHHNG_03066 9.05e-258 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
IIEKHHNG_03067 2.07e-212 - - - S - - - Sodium Bile acid symporter family
IIEKHHNG_03068 1.19e-68 ydeH - - - - - - -
IIEKHHNG_03069 2.9e-254 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
IIEKHHNG_03071 3.29e-36 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
IIEKHHNG_03072 2.58e-37 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
IIEKHHNG_03073 1.88e-98 ykkA - - S - - - Protein of unknown function (DUF664)
IIEKHHNG_03074 1.63e-131 yrkC - - G - - - Cupin domain
IIEKHHNG_03076 9.68e-251 trkA - - P ko:K07222 - ko00000 Oxidoreductase
IIEKHHNG_03077 5.11e-214 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
IIEKHHNG_03078 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
IIEKHHNG_03081 4.11e-82 - - - G - - - Cupin domain
IIEKHHNG_03082 6.08e-102 - - - S - - - DinB superfamily
IIEKHHNG_03083 1.45e-233 - - - S - - - Patatin-like phospholipase
IIEKHHNG_03084 9.96e-69 - - - K - - - Transcriptional regulator PadR-like family
IIEKHHNG_03085 1.48e-133 - - - S - - - Protein of unknown function (DUF2812)
IIEKHHNG_03086 8.33e-156 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
IIEKHHNG_03087 1.25e-166 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
IIEKHHNG_03088 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
IIEKHHNG_03089 1.6e-251 yrkH - - P - - - Rhodanese Homology Domain
IIEKHHNG_03090 3.64e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
IIEKHHNG_03091 1.42e-76 - - - P - - - Rhodanese Homology Domain
IIEKHHNG_03092 9.32e-107 yrkE - - O - - - DsrE/DsrF/DrsH-like family
IIEKHHNG_03093 1.53e-52 yrkD - - S - - - protein conserved in bacteria
IIEKHHNG_03094 8.42e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
IIEKHHNG_03095 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
IIEKHHNG_03096 1.97e-241 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
IIEKHHNG_03097 2.22e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
IIEKHHNG_03098 4.07e-97 ywnA - - K - - - Transcriptional regulator
IIEKHHNG_03099 1.59e-85 - - - S - - - YjbR
IIEKHHNG_03100 2.13e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
IIEKHHNG_03101 1.41e-93 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
IIEKHHNG_03102 1.04e-65 ohrR - - K - - - Transcriptional regulator
IIEKHHNG_03103 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
IIEKHHNG_03105 3.49e-175 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IIEKHHNG_03106 3.81e-56 - - - - - - - -
IIEKHHNG_03108 9.77e-150 - - - S - - - ATPase (AAA superfamily
IIEKHHNG_03117 2.88e-74 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
IIEKHHNG_03118 1.78e-21 - - - - - - - -
IIEKHHNG_03119 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
IIEKHHNG_03120 5.75e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
IIEKHHNG_03121 1.61e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIEKHHNG_03122 7.1e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IIEKHHNG_03123 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
IIEKHHNG_03124 1.25e-241 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
IIEKHHNG_03125 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IIEKHHNG_03126 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
IIEKHHNG_03127 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
IIEKHHNG_03128 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
IIEKHHNG_03129 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IIEKHHNG_03130 3.83e-277 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IIEKHHNG_03131 1.29e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
IIEKHHNG_03132 1.09e-75 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IIEKHHNG_03133 2.96e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
IIEKHHNG_03134 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
IIEKHHNG_03135 1.96e-108 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
IIEKHHNG_03136 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IIEKHHNG_03137 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IIEKHHNG_03138 2.52e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
IIEKHHNG_03139 2.25e-74 ydbP - - CO - - - Thioredoxin
IIEKHHNG_03140 6.66e-159 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIEKHHNG_03141 9.35e-14 - - - S - - - Fur-regulated basic protein A
IIEKHHNG_03142 1.13e-15 - - - S - - - Fur-regulated basic protein B
IIEKHHNG_03143 2.15e-261 ydbM - - I - - - acyl-CoA dehydrogenase
IIEKHHNG_03144 5.4e-69 ydbL - - - - - - -
IIEKHHNG_03145 3.47e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IIEKHHNG_03146 3.37e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_03147 8.61e-231 ydbI - - S - - - AI-2E family transporter
IIEKHHNG_03148 1.59e-286 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIEKHHNG_03149 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IIEKHHNG_03150 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IIEKHHNG_03151 2.58e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IIEKHHNG_03152 1.92e-198 ydbD - - P ko:K07217 - ko00000 Catalase
IIEKHHNG_03153 1.01e-79 ydbC - - S - - - Domain of unknown function (DUF4937
IIEKHHNG_03154 2.65e-78 ydbB - - G - - - Cupin domain
IIEKHHNG_03155 2.34e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
IIEKHHNG_03156 1.09e-181 ydbA - - P - - - EcsC protein family
IIEKHHNG_03157 2.87e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
IIEKHHNG_03158 5.32e-94 yvaD - - S - - - Family of unknown function (DUF5360)
IIEKHHNG_03159 1.95e-45 ydaT - - - - - - -
IIEKHHNG_03161 1.08e-287 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IIEKHHNG_03162 7.45e-54 - - - - - - - -
IIEKHHNG_03163 1.65e-127 - - - - - - - -
IIEKHHNG_03164 2.53e-114 - - - - - - - -
IIEKHHNG_03166 2.69e-12 - - - - - - - -
IIEKHHNG_03168 1.65e-267 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
IIEKHHNG_03170 2.27e-101 - - - - - - - -
IIEKHHNG_03171 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IIEKHHNG_03172 1.04e-74 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IIEKHHNG_03173 0.0 ydaO - - E - - - amino acid
IIEKHHNG_03174 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
IIEKHHNG_03175 2.16e-301 ydaM - - M - - - Glycosyl transferase family group 2
IIEKHHNG_03176 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
IIEKHHNG_03177 2.67e-189 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
IIEKHHNG_03178 1.34e-256 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
IIEKHHNG_03179 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IIEKHHNG_03180 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IIEKHHNG_03181 6.54e-63 ydzA - - EGP - - - Domain of unknown function (DUF3817)
IIEKHHNG_03182 2.54e-176 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IIEKHHNG_03183 1.83e-101 ydaG - - S - - - general stress protein
IIEKHHNG_03184 1.3e-145 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IIEKHHNG_03185 7.9e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
IIEKHHNG_03186 9.37e-208 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIEKHHNG_03187 0.0 ydaB - - IQ - - - acyl-CoA ligase
IIEKHHNG_03188 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
IIEKHHNG_03189 2.57e-221 ycsN - - S - - - Oxidoreductase
IIEKHHNG_03190 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
IIEKHHNG_03191 5.95e-75 yczJ - - S - - - biosynthesis
IIEKHHNG_03193 2.23e-149 ycsK - - E - - - anatomical structure formation involved in morphogenesis
IIEKHHNG_03194 2.69e-166 kipR - - K - - - Transcriptional regulator
IIEKHHNG_03195 1.03e-241 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
IIEKHHNG_03196 2.7e-174 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
IIEKHHNG_03197 1.4e-191 ycsI - - S - - - Belongs to the D-glutamate cyclase family
IIEKHHNG_03198 2.66e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
IIEKHHNG_03199 8.34e-179 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
IIEKHHNG_03200 1.1e-176 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IIEKHHNG_03202 1.38e-85 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
IIEKHHNG_03203 1.21e-265 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
IIEKHHNG_03204 4.11e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IIEKHHNG_03205 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
IIEKHHNG_03206 1.59e-71 - - - - - - - -
IIEKHHNG_03207 4.26e-138 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IIEKHHNG_03208 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
IIEKHHNG_03209 2.05e-131 ycnI - - S - - - protein conserved in bacteria
IIEKHHNG_03210 4.85e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIEKHHNG_03211 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
IIEKHHNG_03212 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IIEKHHNG_03213 2.17e-287 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IIEKHHNG_03214 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIEKHHNG_03215 2.76e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IIEKHHNG_03216 8.02e-59 ycnE - - S - - - Monooxygenase
IIEKHHNG_03217 1.97e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
IIEKHHNG_03218 4.47e-197 ycnC - - K - - - Transcriptional regulator
IIEKHHNG_03219 4.87e-314 ycnB - - EGP - - - the major facilitator superfamily
IIEKHHNG_03220 3.24e-222 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
IIEKHHNG_03221 4.63e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_03222 1.64e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIEKHHNG_03223 3.85e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIEKHHNG_03224 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IIEKHHNG_03226 1.2e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IIEKHHNG_03227 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
IIEKHHNG_03228 2.6e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIEKHHNG_03229 6.53e-309 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
IIEKHHNG_03230 1.62e-158 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IIEKHHNG_03231 0.0 yxeQ - - S - - - MmgE/PrpD family
IIEKHHNG_03232 2.3e-275 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
IIEKHHNG_03233 2.28e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_03234 1.49e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IIEKHHNG_03235 5.21e-182 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IIEKHHNG_03236 4.43e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIEKHHNG_03237 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIEKHHNG_03238 1.86e-248 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
IIEKHHNG_03239 2.82e-300 gerKC - - S ko:K06297 - ko00000 spore germination
IIEKHHNG_03240 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
IIEKHHNG_03242 0.0 yclG - - M - - - Pectate lyase superfamily protein
IIEKHHNG_03243 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
IIEKHHNG_03244 6.81e-100 yclD - - - - - - -
IIEKHHNG_03245 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
IIEKHHNG_03246 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IIEKHHNG_03247 1.4e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IIEKHHNG_03248 5.96e-206 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
IIEKHHNG_03249 8.63e-121 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
IIEKHHNG_03250 3.53e-153 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IIEKHHNG_03251 3.24e-168 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IIEKHHNG_03252 3.11e-144 yczE - - S ko:K07149 - ko00000 membrane
IIEKHHNG_03253 1.3e-167 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
IIEKHHNG_03254 5.72e-316 - - - E - - - Aminotransferase class I and II
IIEKHHNG_03255 3.56e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
IIEKHHNG_03256 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
IIEKHHNG_03257 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIEKHHNG_03258 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIEKHHNG_03259 4.1e-84 hxlR - - K - - - transcriptional
IIEKHHNG_03260 5.21e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
IIEKHHNG_03261 1.22e-121 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
IIEKHHNG_03262 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
IIEKHHNG_03263 6.79e-91 nin - - S - - - Competence protein J (ComJ)
IIEKHHNG_03264 1.37e-43 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IIEKHHNG_03265 9.5e-68 - - - S - - - Protein of unknown function (DUF2680)
IIEKHHNG_03266 2.2e-95 yckC - - S - - - membrane
IIEKHHNG_03267 7.17e-281 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IIEKHHNG_03268 1.73e-290 yciC - - S - - - GTPases (G3E family)
IIEKHHNG_03269 4.05e-285 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IIEKHHNG_03270 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
IIEKHHNG_03271 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IIEKHHNG_03272 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IIEKHHNG_03273 3.45e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
IIEKHHNG_03274 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IIEKHHNG_03275 3.33e-242 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
IIEKHHNG_03276 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
IIEKHHNG_03277 6.34e-311 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IIEKHHNG_03278 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IIEKHHNG_03279 9.61e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IIEKHHNG_03280 8.94e-183 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
IIEKHHNG_03281 3.29e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
IIEKHHNG_03282 1.01e-134 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IIEKHHNG_03283 2.75e-287 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IIEKHHNG_03284 5.46e-188 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
IIEKHHNG_03285 2.44e-141 tmrB - - S - - - AAA domain
IIEKHHNG_03286 2.77e-06 - - - S - - - Bacillus cereus group antimicrobial protein
IIEKHHNG_03287 1.29e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IIEKHHNG_03288 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
IIEKHHNG_03289 1.15e-314 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IIEKHHNG_03290 4.19e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
IIEKHHNG_03291 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
IIEKHHNG_03292 2.82e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
IIEKHHNG_03293 0.0 mdr - - EGP - - - the major facilitator superfamily
IIEKHHNG_03294 6.6e-228 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IIEKHHNG_03295 5.7e-32 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
IIEKHHNG_03296 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
IIEKHHNG_03297 4.41e-106 ycgB - - - - - - -
IIEKHHNG_03298 8.03e-294 ycgA - - S - - - Membrane
IIEKHHNG_03299 4.59e-270 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
IIEKHHNG_03300 2.85e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IIEKHHNG_03301 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IIEKHHNG_03302 1.28e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
IIEKHHNG_03303 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
IIEKHHNG_03304 4.74e-246 yceH - - P - - - Belongs to the TelA family
IIEKHHNG_03305 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
IIEKHHNG_03306 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
IIEKHHNG_03307 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IIEKHHNG_03308 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IIEKHHNG_03309 4.06e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
IIEKHHNG_03310 6.94e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIEKHHNG_03311 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IIEKHHNG_03312 5.69e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IIEKHHNG_03313 3.64e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IIEKHHNG_03314 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IIEKHHNG_03315 1.23e-178 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
IIEKHHNG_03316 5.77e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
IIEKHHNG_03317 1.79e-121 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IIEKHHNG_03318 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IIEKHHNG_03319 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IIEKHHNG_03320 6.27e-224 ycdA - - S - - - Domain of unknown function (DUF5105)
IIEKHHNG_03321 9e-129 yccK - - C - - - Aldo keto reductase
IIEKHHNG_03322 6.12e-69 yccK - - C - - - Aldo keto reductase
IIEKHHNG_03323 9.7e-252 yccF - - K ko:K07039 - ko00000 SEC-C motif
IIEKHHNG_03324 3.29e-147 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
IIEKHHNG_03325 1.8e-250 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IIEKHHNG_03326 1.04e-128 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IIEKHHNG_03327 1.68e-311 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
IIEKHHNG_03328 1.92e-263 ycbU - - E - - - Selenocysteine lyase
IIEKHHNG_03329 4.68e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IIEKHHNG_03330 4.24e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IIEKHHNG_03331 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IIEKHHNG_03332 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
IIEKHHNG_03333 1.44e-99 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
IIEKHHNG_03334 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
IIEKHHNG_03335 2.56e-72 ydfQ - - CO - - - Thioredoxin
IIEKHHNG_03336 1.14e-83 ydfP - - S ko:K15977 - ko00000 DoxX
IIEKHHNG_03337 2.06e-233 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IIEKHHNG_03338 9.49e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
IIEKHHNG_03339 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIEKHHNG_03340 4.85e-35 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
IIEKHHNG_03341 2.46e-08 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
IIEKHHNG_03342 5.81e-221 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
IIEKHHNG_03343 1.26e-278 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IIEKHHNG_03344 1.11e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IIEKHHNG_03345 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IIEKHHNG_03346 1.69e-229 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
IIEKHHNG_03347 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IIEKHHNG_03348 8.33e-255 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IIEKHHNG_03349 1.17e-271 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIEKHHNG_03350 5.76e-245 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
IIEKHHNG_03351 8.67e-55 ybfN - - - - - - -
IIEKHHNG_03352 7.49e-195 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IIEKHHNG_03353 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
IIEKHHNG_03354 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IIEKHHNG_03355 1.87e-270 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IIEKHHNG_03356 8.67e-255 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
IIEKHHNG_03357 1.14e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
IIEKHHNG_03358 2.1e-71 - - - M - - - nucleic acid phosphodiester bond hydrolysis
IIEKHHNG_03359 4.73e-176 draG - - O - - - ADP-ribosylglycohydrolase
IIEKHHNG_03361 8.96e-67 - - - S ko:K19169 - ko00000,ko02048 DNA-sulfur modification-associated
IIEKHHNG_03362 1.14e-25 - - - S ko:K19169 - ko00000,ko02048 DNA-sulfur modification-associated
IIEKHHNG_03363 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
IIEKHHNG_03365 1.66e-266 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
IIEKHHNG_03366 5.8e-23 - - - S - - - Protein of unknown function (DUF2651)
IIEKHHNG_03367 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
IIEKHHNG_03368 8.18e-211 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
IIEKHHNG_03369 6.28e-23 - - - S - - - Protein of unknown function (DUF2651)
IIEKHHNG_03371 5.3e-62 - - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IIEKHHNG_03372 0.0 ybeC - - E - - - amino acid
IIEKHHNG_03373 7.84e-55 ybyB - - - - - - -
IIEKHHNG_03374 4.16e-143 yqeB - - - - - - -
IIEKHHNG_03375 1.01e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
IIEKHHNG_03376 6.08e-102 - - - S - - - Domain of unknown function (DUF4879)
IIEKHHNG_03377 2.34e-35 - - - - - - - -
IIEKHHNG_03378 1.32e-252 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IIEKHHNG_03379 3.18e-263 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IIEKHHNG_03380 6.21e-214 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
IIEKHHNG_03381 2.04e-141 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
IIEKHHNG_03382 2.38e-253 - - - T - - - COG4585 Signal transduction histidine kinase
IIEKHHNG_03383 1.07e-118 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IIEKHHNG_03384 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IIEKHHNG_03386 5.62e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IIEKHHNG_03387 9.9e-68 - - - S ko:K06518 - ko00000,ko02000 LrgA family
IIEKHHNG_03388 6.05e-135 yxaC - - M - - - effector of murein hydrolase
IIEKHHNG_03389 1.03e-206 dkgB - - S - - - Aldo/keto reductase family
IIEKHHNG_03391 4.5e-15 - - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IIEKHHNG_03392 0.0 - - - V ko:K02004,ko:K11632 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IIEKHHNG_03393 6.57e-176 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IIEKHHNG_03394 2.32e-235 - - - T ko:K19168 - ko00000,ko02048 Histidine kinase
IIEKHHNG_03395 8.72e-163 - - - T ko:K11630 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIEKHHNG_03396 1.42e-138 - - - S - - - ABC-2 family transporter protein
IIEKHHNG_03397 2.14e-199 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IIEKHHNG_03398 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IIEKHHNG_03399 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IIEKHHNG_03400 7.18e-291 ybbR - - S - - - protein conserved in bacteria
IIEKHHNG_03401 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IIEKHHNG_03402 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IIEKHHNG_03403 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IIEKHHNG_03409 1.93e-101 ybbK - - S - - - Protein of unknown function (DUF523)
IIEKHHNG_03410 7.13e-110 ybbJ - - J - - - acetyltransferase
IIEKHHNG_03411 3.84e-207 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IIEKHHNG_03412 5.86e-310 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IIEKHHNG_03413 2.56e-308 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
IIEKHHNG_03414 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
IIEKHHNG_03415 2.61e-299 ybbC - - S - - - protein conserved in bacteria
IIEKHHNG_03416 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
IIEKHHNG_03417 1.21e-219 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
IIEKHHNG_03418 1.8e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIEKHHNG_03419 1.43e-229 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIEKHHNG_03420 1.35e-143 ybbA - - S ko:K07017 - ko00000 Putative esterase
IIEKHHNG_03421 1.08e-222 ybaS - - S - - - Na -dependent transporter
IIEKHHNG_03422 2.62e-286 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IIEKHHNG_03423 3.13e-253 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
IIEKHHNG_03424 7.74e-231 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
IIEKHHNG_03425 1.22e-311 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IIEKHHNG_03426 3.31e-281 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
IIEKHHNG_03429 4e-233 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IIEKHHNG_03430 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
IIEKHHNG_03431 1.02e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
IIEKHHNG_03432 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IIEKHHNG_03433 6.49e-245 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IIEKHHNG_03434 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
IIEKHHNG_03435 2.84e-115 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IIEKHHNG_03436 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IIEKHHNG_03437 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IIEKHHNG_03438 1.92e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IIEKHHNG_03439 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
IIEKHHNG_03440 2.27e-162 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
IIEKHHNG_03441 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IIEKHHNG_03442 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IIEKHHNG_03443 0.0 yvfT - - T - - - helix_turn_helix, Lux Regulon
IIEKHHNG_03444 2.24e-127 - - - S - - - Putative sensor
IIEKHHNG_03445 0.0 pbpX - - V - - - Beta-lactamase
IIEKHHNG_03446 2.41e-98 yfiJ - - T - - - helix_turn_helix, Lux Regulon
IIEKHHNG_03447 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
IIEKHHNG_03448 1.69e-255 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
IIEKHHNG_03449 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
IIEKHHNG_03450 5.78e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
IIEKHHNG_03451 3.61e-41 yjdJ - - S - - - Domain of unknown function (DUF4306)
IIEKHHNG_03452 9.58e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
IIEKHHNG_03453 3.49e-226 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IIEKHHNG_03454 4.16e-160 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
IIEKHHNG_03455 3.22e-223 ydjI - - S - - - virion core protein (lumpy skin disease virus)
IIEKHHNG_03456 0.0 oatA - - I - - - Acyltransferase family
IIEKHHNG_03457 9.73e-194 rsiV - - S - - - Protein of unknown function (DUF3298)
IIEKHHNG_03458 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IIEKHHNG_03459 1e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
IIEKHHNG_03460 1.6e-82 ydjM - - M - - - Lytic transglycolase
IIEKHHNG_03461 7.08e-195 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
IIEKHHNG_03463 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
IIEKHHNG_03464 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
IIEKHHNG_03465 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IIEKHHNG_03466 3.25e-225 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
IIEKHHNG_03467 3.13e-274 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IIEKHHNG_03468 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
IIEKHHNG_03469 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
IIEKHHNG_03470 5.95e-102 - - - - - - - -
IIEKHHNG_03471 1.9e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IIEKHHNG_03472 0.0 - - - S - - - Domain of unknown function (DUF4179)
IIEKHHNG_03473 1.23e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
IIEKHHNG_03474 2.16e-168 yebC - - M - - - Membrane
IIEKHHNG_03476 2.66e-120 yebE - - S - - - UPF0316 protein
IIEKHHNG_03477 2.21e-38 yebG - - S - - - NETI protein
IIEKHHNG_03478 3.78e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IIEKHHNG_03479 4.56e-287 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IIEKHHNG_03480 2.59e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IIEKHHNG_03481 2.79e-165 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
IIEKHHNG_03482 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIEKHHNG_03483 1.34e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIEKHHNG_03484 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIEKHHNG_03485 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IIEKHHNG_03486 1.46e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
IIEKHHNG_03487 9.96e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IIEKHHNG_03488 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
IIEKHHNG_03489 8.44e-300 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
IIEKHHNG_03490 1.03e-34 - - - S - - - Protein of unknown function (DUF2892)
IIEKHHNG_03491 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
IIEKHHNG_03492 4.95e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
IIEKHHNG_03493 2.03e-67 yerC - - S - - - protein conserved in bacteria
IIEKHHNG_03494 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
IIEKHHNG_03495 8.71e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IIEKHHNG_03496 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
IIEKHHNG_03497 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IIEKHHNG_03498 5.54e-286 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
IIEKHHNG_03499 2.19e-249 yerI - - S - - - homoserine kinase type II (protein kinase fold)
IIEKHHNG_03500 1.44e-158 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
IIEKHHNG_03501 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IIEKHHNG_03502 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIEKHHNG_03503 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IIEKHHNG_03504 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIEKHHNG_03505 3.16e-197 yerO - - K - - - Transcriptional regulator
IIEKHHNG_03506 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IIEKHHNG_03507 7.33e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IIEKHHNG_03508 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIEKHHNG_03509 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
IIEKHHNG_03510 9.62e-203 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IIEKHHNG_03511 6.78e-176 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
IIEKHHNG_03512 2.31e-80 - - - S - - - Protein of unknown function, DUF600
IIEKHHNG_03513 8.27e-67 - - - S - - - Protein of unknown function, DUF600
IIEKHHNG_03514 2.57e-60 - - - S - - - Protein of unknown function, DUF600
IIEKHHNG_03515 7.72e-68 - - - S - - - Protein of unknown function, DUF600
IIEKHHNG_03516 2.38e-101 - - - S - - - Protein of unknown function, DUF600
IIEKHHNG_03517 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
IIEKHHNG_03518 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
IIEKHHNG_03520 2.21e-138 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
IIEKHHNG_03521 2.67e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
IIEKHHNG_03522 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
IIEKHHNG_03523 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
IIEKHHNG_03524 1.39e-123 yesJ - - K - - - Acetyltransferase (GNAT) family
IIEKHHNG_03525 5.92e-05 - - - - - - - -
IIEKHHNG_03526 8.99e-157 yetF - - S - - - membrane
IIEKHHNG_03527 1.11e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
IIEKHHNG_03528 3.78e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIEKHHNG_03529 6.28e-197 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IIEKHHNG_03530 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
IIEKHHNG_03531 1.82e-73 - - - H - - - riboflavin kinase activity
IIEKHHNG_03532 1.8e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
IIEKHHNG_03533 3.45e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
IIEKHHNG_03534 2.19e-267 yetM - - CH - - - FAD binding domain
IIEKHHNG_03535 2.28e-250 yetN - - S - - - Protein of unknown function (DUF3900)
IIEKHHNG_03536 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IIEKHHNG_03538 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IIEKHHNG_03539 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
IIEKHHNG_03540 3.93e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
IIEKHHNG_03541 1.9e-229 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
IIEKHHNG_03542 7.24e-285 yfnE - - S - - - Glycosyltransferase like family 2
IIEKHHNG_03543 1.99e-238 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
IIEKHHNG_03544 1.56e-277 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IIEKHHNG_03545 8.39e-313 yfnA - - E ko:K03294 - ko00000 amino acid
IIEKHHNG_03546 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IIEKHHNG_03547 2.85e-169 yfmS - - NT - - - chemotaxis protein
IIEKHHNG_03548 1.72e-214 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IIEKHHNG_03549 1.2e-265 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
IIEKHHNG_03550 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IIEKHHNG_03551 2.05e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
IIEKHHNG_03552 5.93e-263 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
IIEKHHNG_03553 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IIEKHHNG_03554 1.78e-264 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
IIEKHHNG_03555 9.42e-83 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
IIEKHHNG_03556 1.84e-236 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
IIEKHHNG_03557 7.35e-32 - - - S - - - Protein of unknown function (DUF3212)
IIEKHHNG_03558 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
IIEKHHNG_03559 3.93e-309 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
IIEKHHNG_03560 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
IIEKHHNG_03566 7.54e-07 - - - S - - - domain, Protein
IIEKHHNG_03568 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IIEKHHNG_03569 1.38e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
IIEKHHNG_03570 5.87e-228 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
IIEKHHNG_03571 1.65e-286 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IIEKHHNG_03572 1.4e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IIEKHHNG_03573 1.74e-278 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IIEKHHNG_03574 4.77e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
IIEKHHNG_03575 2.82e-155 yflK - - S - - - protein conserved in bacteria
IIEKHHNG_03576 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
IIEKHHNG_03577 1.98e-26 yflI - - - - - - -
IIEKHHNG_03578 1.67e-66 yflH - - S - - - Protein of unknown function (DUF3243)
IIEKHHNG_03579 9.02e-176 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IIEKHHNG_03580 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IIEKHHNG_03581 2.02e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
IIEKHHNG_03582 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IIEKHHNG_03583 8.46e-84 ydhN1 - - S - - - Domain of unknown function (DUF1992)
IIEKHHNG_03584 1.18e-103 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IIEKHHNG_03585 6.73e-51 ydgA - - S - - - Spore germination protein gerPA/gerPF
IIEKHHNG_03586 5.99e-50 ydgB - - S - - - Spore germination protein gerPA/gerPF
IIEKHHNG_03587 1.57e-313 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IIEKHHNG_03588 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
IIEKHHNG_03589 1.18e-165 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
IIEKHHNG_03590 2.93e-158 frp - - C - - - nitroreductase
IIEKHHNG_03591 6e-167 yibF - - S - - - YibE/F-like protein
IIEKHHNG_03592 1.02e-246 yibE - - S - - - YibE/F-like protein
IIEKHHNG_03593 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
IIEKHHNG_03594 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IIEKHHNG_03595 6.43e-239 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IIEKHHNG_03596 5.86e-208 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IIEKHHNG_03597 3.38e-173 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IIEKHHNG_03598 6.98e-252 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IIEKHHNG_03599 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
IIEKHHNG_03600 1.69e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIEKHHNG_03601 3.7e-70 yfkI - - S - - - gas vesicle protein
IIEKHHNG_03602 1.95e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
IIEKHHNG_03603 6.71e-12 - - - - - - - -
IIEKHHNG_03604 4.6e-265 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IIEKHHNG_03605 1.4e-237 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
IIEKHHNG_03606 1.62e-185 yfkD - - S - - - YfkD-like protein
IIEKHHNG_03607 5.2e-189 yfkC - - M - - - Mechanosensitive ion channel
IIEKHHNG_03608 2.92e-282 yfkA - - S - - - YfkB-like domain
IIEKHHNG_03609 7.99e-37 yfjT - - - - - - -
IIEKHHNG_03610 3.59e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
IIEKHHNG_03611 4.82e-184 - - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IIEKHHNG_03612 1.12e-103 - - - S ko:K19310 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacitracin ABC transporter permease
IIEKHHNG_03613 8.75e-92 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Bacitracin ABC transporter permease
IIEKHHNG_03614 4.57e-138 - - - K - - - Two component transcriptional regulator, winged helix family
IIEKHHNG_03615 2.8e-139 - - - T - - - His Kinase A (phosphoacceptor) domain
IIEKHHNG_03616 1.09e-190 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IIEKHHNG_03618 3.71e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
IIEKHHNG_03619 5.07e-201 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IIEKHHNG_03620 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIEKHHNG_03621 1.64e-62 - - - S - - - YfzA-like protein
IIEKHHNG_03622 3.47e-244 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIEKHHNG_03623 6.01e-115 yfjM - - S - - - Psort location Cytoplasmic, score
IIEKHHNG_03624 6.48e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IIEKHHNG_03625 1.52e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IIEKHHNG_03626 5.38e-272 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IIEKHHNG_03627 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IIEKHHNG_03628 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
IIEKHHNG_03629 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
IIEKHHNG_03630 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IIEKHHNG_03631 9.01e-178 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
IIEKHHNG_03632 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IIEKHHNG_03633 3.72e-228 yobO - - M - - - COG5434 Endopolygalacturonase
IIEKHHNG_03634 1.89e-279 yobO - - M - - - COG5434 Endopolygalacturonase
IIEKHHNG_03635 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
IIEKHHNG_03636 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IIEKHHNG_03637 5.54e-82 yfiD3 - - S - - - DoxX
IIEKHHNG_03638 4.72e-205 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
IIEKHHNG_03639 7.58e-217 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IIEKHHNG_03640 5.62e-126 padR - - K - - - transcriptional
IIEKHHNG_03641 1.79e-144 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
IIEKHHNG_03642 7.69e-236 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IIEKHHNG_03643 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
IIEKHHNG_03644 2.36e-60 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
IIEKHHNG_03645 1.14e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
IIEKHHNG_03646 0.0 yfiU - - EGP - - - the major facilitator superfamily
IIEKHHNG_03647 7.97e-108 yfiV - - K - - - transcriptional
IIEKHHNG_03648 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IIEKHHNG_03649 7.26e-209 yfhB - - S - - - PhzF family
IIEKHHNG_03650 1.94e-136 yfhC - - C - - - nitroreductase
IIEKHHNG_03651 3.61e-34 yfhD - - S - - - YfhD-like protein
IIEKHHNG_03653 3.34e-212 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
IIEKHHNG_03654 3.01e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
IIEKHHNG_03655 1.12e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
IIEKHHNG_03656 2.86e-268 yfhI - - EGP - - - -transporter
IIEKHHNG_03658 3.34e-214 mpr - - M - - - Belongs to the peptidase S1B family
IIEKHHNG_03659 2.57e-59 yfhJ - - S - - - WVELL protein
IIEKHHNG_03660 3.85e-120 yfhK - - T - - - Bacterial SH3 domain homologues
IIEKHHNG_03661 2.99e-57 yfhL - - S - - - SdpI/YhfL protein family
IIEKHHNG_03662 6.8e-219 - - - S - - - Alpha/beta hydrolase family
IIEKHHNG_03663 1.57e-235 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IIEKHHNG_03664 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
IIEKHHNG_03665 2.94e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
IIEKHHNG_03666 9.18e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
IIEKHHNG_03667 2.54e-50 yfhS - - - - - - -
IIEKHHNG_03668 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIEKHHNG_03669 7.33e-07 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
IIEKHHNG_03670 1.4e-49 ygaB - - S - - - YgaB-like protein
IIEKHHNG_03671 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
IIEKHHNG_03672 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
IIEKHHNG_03673 5.27e-239 ygaE - - S - - - Membrane
IIEKHHNG_03674 2.79e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IIEKHHNG_03675 3.28e-110 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
IIEKHHNG_03676 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
IIEKHHNG_03677 4.67e-75 ygzB - - S - - - UPF0295 protein
IIEKHHNG_03678 1.12e-212 ygxA - - S - - - Nucleotidyltransferase-like
IIEKHHNG_03679 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
IIEKHHNG_03680 1.14e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
IIEKHHNG_03681 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IIEKHHNG_03682 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
IIEKHHNG_03683 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IIEKHHNG_03684 7.66e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IIEKHHNG_03685 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
IIEKHHNG_03686 2.38e-158 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IIEKHHNG_03687 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IIEKHHNG_03688 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IIEKHHNG_03689 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
IIEKHHNG_03690 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IIEKHHNG_03691 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IIEKHHNG_03692 1.01e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIEKHHNG_03693 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
IIEKHHNG_03694 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
IIEKHHNG_03695 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IIEKHHNG_03696 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IIEKHHNG_03697 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IIEKHHNG_03698 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IIEKHHNG_03699 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IIEKHHNG_03700 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IIEKHHNG_03701 1.2e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
IIEKHHNG_03702 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIEKHHNG_03703 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIEKHHNG_03704 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
IIEKHHNG_03705 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IIEKHHNG_03706 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IIEKHHNG_03707 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IIEKHHNG_03708 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IIEKHHNG_03709 2.33e-239 ybaC - - S - - - Alpha/beta hydrolase family
IIEKHHNG_03710 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
IIEKHHNG_03711 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IIEKHHNG_03712 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
IIEKHHNG_03713 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IIEKHHNG_03714 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IIEKHHNG_03715 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IIEKHHNG_03716 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IIEKHHNG_03717 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IIEKHHNG_03718 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IIEKHHNG_03719 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
IIEKHHNG_03720 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IIEKHHNG_03721 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IIEKHHNG_03722 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IIEKHHNG_03723 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IIEKHHNG_03724 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IIEKHHNG_03725 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IIEKHHNG_03726 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IIEKHHNG_03727 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IIEKHHNG_03728 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IIEKHHNG_03729 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
IIEKHHNG_03730 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IIEKHHNG_03731 1.34e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IIEKHHNG_03732 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IIEKHHNG_03733 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IIEKHHNG_03734 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IIEKHHNG_03735 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
IIEKHHNG_03736 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IIEKHHNG_03737 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IIEKHHNG_03738 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIEKHHNG_03739 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
IIEKHHNG_03740 1.45e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIEKHHNG_03741 2.09e-191 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIEKHHNG_03742 7.93e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIEKHHNG_03743 3.56e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IIEKHHNG_03744 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IIEKHHNG_03745 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
IIEKHHNG_03746 1.76e-185 ybaJ - - Q - - - Methyltransferase domain
IIEKHHNG_03747 9.4e-110 yizA - - S - - - Damage-inducible protein DinB
IIEKHHNG_03748 9.25e-103 ybaK - - S - - - Protein of unknown function (DUF2521)
IIEKHHNG_03749 2.31e-172 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IIEKHHNG_03750 9e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IIEKHHNG_03751 1.95e-102 gerD - - - ko:K06294 - ko00000 -
IIEKHHNG_03752 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
IIEKHHNG_03753 6.38e-183 pdaB - - G - - - Polysaccharide deacetylase
IIEKHHNG_03754 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
IIEKHHNG_03755 7.19e-137 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IIEKHHNG_03756 2.32e-242 yaaN - - P - - - Belongs to the TelA family
IIEKHHNG_03757 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
IIEKHHNG_03758 1.9e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IIEKHHNG_03759 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
IIEKHHNG_03760 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
IIEKHHNG_03761 1.9e-233 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IIEKHHNG_03762 9e-189 yaaT - - S - - - stage 0 sporulation protein
IIEKHHNG_03763 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
IIEKHHNG_03764 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
IIEKHHNG_03765 6.96e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
IIEKHHNG_03766 1.65e-209 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IIEKHHNG_03767 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
IIEKHHNG_03768 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IIEKHHNG_03769 1.02e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
IIEKHHNG_03770 3.23e-306 yabE - - T - - - protein conserved in bacteria
IIEKHHNG_03771 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IIEKHHNG_03772 2.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IIEKHHNG_03773 6.71e-208 yabG - - S ko:K06436 - ko00000 peptidase
IIEKHHNG_03774 3.08e-52 veg - - S - - - protein conserved in bacteria
IIEKHHNG_03775 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
IIEKHHNG_03776 2.73e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IIEKHHNG_03777 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
IIEKHHNG_03778 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
IIEKHHNG_03779 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IIEKHHNG_03780 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IIEKHHNG_03781 2.47e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIEKHHNG_03782 3.57e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IIEKHHNG_03783 1.74e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IIEKHHNG_03784 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
IIEKHHNG_03785 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IIEKHHNG_03786 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
IIEKHHNG_03787 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IIEKHHNG_03788 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IIEKHHNG_03789 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IIEKHHNG_03790 5.47e-66 yabP - - S - - - Sporulation protein YabP
IIEKHHNG_03791 1.95e-133 yabQ - - S - - - spore cortex biosynthesis protein
IIEKHHNG_03792 6.94e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
IIEKHHNG_03793 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IIEKHHNG_03796 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
IIEKHHNG_03797 5.38e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IIEKHHNG_03798 3.3e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
IIEKHHNG_03799 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IIEKHHNG_03800 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
IIEKHHNG_03801 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IIEKHHNG_03802 6.64e-187 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IIEKHHNG_03803 1.3e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IIEKHHNG_03804 1.16e-193 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
IIEKHHNG_03805 2.09e-215 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IIEKHHNG_03806 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IIEKHHNG_03807 2.97e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
IIEKHHNG_03808 2.83e-206 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
IIEKHHNG_03809 2.24e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IIEKHHNG_03810 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IIEKHHNG_03811 3.34e-117 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IIEKHHNG_03812 8.67e-40 yazB - - K - - - transcriptional
IIEKHHNG_03813 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIEKHHNG_03814 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
IIEKHHNG_03815 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
IIEKHHNG_03816 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
IIEKHHNG_03817 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IIEKHHNG_03818 9.8e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IIEKHHNG_03819 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIEKHHNG_03820 2.48e-111 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IIEKHHNG_03821 1.44e-128 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
IIEKHHNG_03822 5.59e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
IIEKHHNG_03823 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
IIEKHHNG_03824 7.51e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
IIEKHHNG_03826 1.9e-257 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
IIEKHHNG_03827 1.3e-284 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IIEKHHNG_03828 2.86e-139 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IIEKHHNG_03829 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IIEKHHNG_03830 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IIEKHHNG_03831 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IIEKHHNG_03832 8.24e-234 yaaC - - S - - - YaaC-like Protein
IIEKHHNG_03834 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIEKHHNG_03835 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)