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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NHKNCPHF_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHKNCPHF_00002	2.28e-172	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NHKNCPHF_00003	2.48e-275	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NHKNCPHF_00004	2.89e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHKNCPHF_00005	9.43e-155	yoaK	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NHKNCPHF_00009	0.0	XK27_10405	-	-	S	-	-	-	Bacterial membrane protein YfhO
NHKNCPHF_00010	0.0	ykpA	-	-	S	-	-	-	abc transporter atp-binding protein
NHKNCPHF_00011	3.8e-193	XK27_10395	-	-	S	-	-	-	membrane
NHKNCPHF_00012	1.12e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
NHKNCPHF_00013	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NHKNCPHF_00014	3.56e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHKNCPHF_00015	5.94e-75	yaaA	-	-	S	-	-	-	S4 domain protein YaaA
NHKNCPHF_00016	2.3e-294	albE	-	-	S	-	-	-	Peptidase M16
NHKNCPHF_00017	1.02e-297	ymfH	-	-	S	-	-	-	Peptidase M16
NHKNCPHF_00018	2.87e-167	-	-	-	S	ko:K15539	-	ko00000	sequence-specific DNA binding
NHKNCPHF_00019	2.68e-118	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHKNCPHF_00020	2.6e-193	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHKNCPHF_00021	3.85e-197	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHKNCPHF_00022	4.35e-170	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHKNCPHF_00023	3.42e-103	lytE	-	-	M	-	-	-	LysM domain protein
NHKNCPHF_00024	1.96e-125	isaA	-	-	M	-	-	-	Immunodominant staphylococcal antigen A
NHKNCPHF_00025	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NHKNCPHF_00026	6.6e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHKNCPHF_00027	6.35e-131	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
NHKNCPHF_00028	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHKNCPHF_00029	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NHKNCPHF_00030	1.77e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NHKNCPHF_00031	1.35e-314	dnaC	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NHKNCPHF_00032	6.16e-63	WQ51_01655	-	-	S	-	-	-	Biofilm formation stimulator VEG
NHKNCPHF_00033	1.25e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHKNCPHF_00034	5.32e-13	-	-	-	-	-	-	-	-
NHKNCPHF_00035	1.32e-71	XK27_04840	-	-	M	ko:K08987	-	ko00000	Membrane
NHKNCPHF_00036	1.69e-125	XK27_06935	-	-	K	-	-	-	transcriptional regulator
NHKNCPHF_00037	1.32e-262	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
NHKNCPHF_00038	7.24e-145	-	-	-	S	-	-	-	Putative adhesin
NHKNCPHF_00039	1.48e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
NHKNCPHF_00040	8.74e-69	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator, PadR family
NHKNCPHF_00041	3.9e-149	XK27_06885	-	-	L	-	-	-	hydrolase
NHKNCPHF_00045	0.0	-	-	-	-	-	-	-	-
NHKNCPHF_00046	0.0	-	2.4.1.12	GT2	M	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
NHKNCPHF_00047	2.11e-217	-	-	-	M	-	-	-	COG0463, glycosyltransferases involved in cell wall biogenesis
NHKNCPHF_00048	1.15e-05	-	-	-	M	-	-	-	COG0463, glycosyltransferases involved in cell wall biogenesis
NHKNCPHF_00049	1.07e-217	-	-	-	T	-	-	-	Diguanylate cyclase
NHKNCPHF_00050	4.19e-46	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NHKNCPHF_00051	4.67e-77	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
NHKNCPHF_00052	1.02e-236	-	-	-	L	-	-	-	Transposase
NHKNCPHF_00053	8.84e-80	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
NHKNCPHF_00054	4.56e-275	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NHKNCPHF_00055	0.0	-	-	-	K	-	-	-	Transcriptional regulator
NHKNCPHF_00056	6.74e-80	-	-	-	-	-	-	-	-
NHKNCPHF_00059	1.54e-80	-	-	-	-	-	-	-	-
NHKNCPHF_00060	9.72e-254	-	-	-	L	-	-	-	Replication initiation factor
NHKNCPHF_00062	0.0	-	-	-	L	-	-	-	DNA integration
NHKNCPHF_00063	1.18e-292	-	-	-	-	-	-	-	-
NHKNCPHF_00064	1.37e-164	-	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHKNCPHF_00065	1.22e-26	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NHKNCPHF_00066	8.74e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NHKNCPHF_00067	1.75e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
NHKNCPHF_00068	9.42e-133	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHKNCPHF_00069	1.01e-95	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHKNCPHF_00070	1.08e-304	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NHKNCPHF_00072	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NHKNCPHF_00073	3.6e-214	XK27_01785	-	-	S	-	-	-	cog cog1284
NHKNCPHF_00074	3.38e-158	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NHKNCPHF_00075	8.87e-150	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHKNCPHF_00076	4.23e-115	-	-	-	K	-	-	-	acetyltransferase
NHKNCPHF_00077	7.68e-20	-	-	-	-	-	-	-	-
NHKNCPHF_00078	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
NHKNCPHF_00079	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHKNCPHF_00080	1.34e-62	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NHKNCPHF_00081	5.68e-91	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHKNCPHF_00082	9.75e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NHKNCPHF_00083	1.73e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NHKNCPHF_00084	5.94e-300	rarA	-	-	L	ko:K07478	-	ko00000	ATPase related to the helicase subunit of the Holliday junction resolvase
NHKNCPHF_00086	5.86e-276	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NHKNCPHF_00087	1.95e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
NHKNCPHF_00088	4.19e-195	-	-	-	L	-	-	-	Replication initiation factor
NHKNCPHF_00089	6.96e-116	-	-	-	K	-	-	-	TRANSCRIPTIONal
NHKNCPHF_00090	7.14e-105	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NHKNCPHF_00091	9.55e-116	flaR	-	-	F	-	-	-	topology modulation protein
NHKNCPHF_00092	3.87e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHKNCPHF_00093	3.12e-104	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHKNCPHF_00094	3.45e-47	-	-	-	S	-	-	-	MORN repeat protein
NHKNCPHF_00095	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase
NHKNCPHF_00096	4.89e-238	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHKNCPHF_00097	4.29e-64	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NHKNCPHF_00098	2.6e-141	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHKNCPHF_00099	2.13e-135	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NHKNCPHF_00100	6e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHKNCPHF_00101	5.06e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHKNCPHF_00102	8.13e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHKNCPHF_00103	1.21e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHKNCPHF_00104	9.44e-153	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHKNCPHF_00105	4.35e-94	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHKNCPHF_00106	6.2e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NHKNCPHF_00107	3.08e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHKNCPHF_00108	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHKNCPHF_00109	5.67e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHKNCPHF_00110	5.86e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHKNCPHF_00111	2.03e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHKNCPHF_00112	3.78e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHKNCPHF_00113	5.88e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHKNCPHF_00114	7.15e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHKNCPHF_00115	7e-104	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHKNCPHF_00116	9.89e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l30
NHKNCPHF_00117	8.47e-85	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NHKNCPHF_00118	8.65e-293	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHKNCPHF_00119	1.02e-149	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHKNCPHF_00120	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHKNCPHF_00121	3.26e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NHKNCPHF_00122	4.42e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHKNCPHF_00123	1.63e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHKNCPHF_00124	7.63e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHKNCPHF_00125	3.03e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l17
NHKNCPHF_00126	9.64e-317	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
NHKNCPHF_00128	4.93e-211	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	aldolase
NHKNCPHF_00130	4.77e-124	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
NHKNCPHF_00131	7.1e-162	treR	-	-	K	ko:K03486	-	ko00000,ko03000	trehalose operon
NHKNCPHF_00132	0.0	treP	2.7.1.201	-	G	ko:K02817,ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHKNCPHF_00133	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
NHKNCPHF_00134	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NHKNCPHF_00135	0.0	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NHKNCPHF_00138	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
NHKNCPHF_00139	1.41e-285	norN	-	-	V	-	-	-	Mate efflux family protein
NHKNCPHF_00140	1.87e-76	asp	-	-	S	-	-	-	cog cog1302
NHKNCPHF_00141	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
NHKNCPHF_00142	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
NHKNCPHF_00143	0.0	ilvB	2.2.1.6	-	EH	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
NHKNCPHF_00144	7.09e-101	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
NHKNCPHF_00145	1.73e-246	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NHKNCPHF_00146	6.44e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHKNCPHF_00147	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NHKNCPHF_00148	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHKNCPHF_00149	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHKNCPHF_00150	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHKNCPHF_00151	1.37e-91	-	-	-	S	-	-	-	cog cog4699
NHKNCPHF_00152	3.13e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NHKNCPHF_00153	5.99e-178	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NHKNCPHF_00154	1.1e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
NHKNCPHF_00155	2.8e-91	cglD	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	Competence protein
NHKNCPHF_00156	5e-21	-	-	-	NU	-	-	-	Type II secretory pathway pseudopilin
NHKNCPHF_00157	9.27e-93	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Competence protein ComGF
NHKNCPHF_00158	5.13e-17	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
NHKNCPHF_00159	1.18e-226	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
NHKNCPHF_00160	3.17e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHKNCPHF_00161	1.05e-36	lanR	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
NHKNCPHF_00162	8.14e-134	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
NHKNCPHF_00164	4.3e-130	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
NHKNCPHF_00165	3.21e-168	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHKNCPHF_00166	8.72e-259	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
NHKNCPHF_00168	2.86e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
NHKNCPHF_00170	4.53e-146	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHKNCPHF_00171	6.39e-21	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NHKNCPHF_00172	8.75e-78	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NHKNCPHF_00173	1.28e-85	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHKNCPHF_00174	4.02e-116	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHKNCPHF_00178	4.52e-200	rrmA	2.1.1.187	-	Q	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	methyltransferase
NHKNCPHF_00179	1.62e-174	-	-	-	S	ko:K07025	-	ko00000	HAD hydrolase, family IA, variant
NHKNCPHF_00180	3.08e-109	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHKNCPHF_00181	6.63e-281	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHKNCPHF_00182	1.99e-122	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHKNCPHF_00183	3.26e-152	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
NHKNCPHF_00184	2.76e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NHKNCPHF_00185	7.25e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NHKNCPHF_00186	2.37e-124	XK27_08585	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
NHKNCPHF_00187	1.49e-181	nirC_1	-	-	P	-	-	-	Formate nitrite transporter
NHKNCPHF_00188	3.61e-307	XK27_09615	-	-	C	ko:K19784	-	ko00000	reductase
NHKNCPHF_00189	1.58e-138	XK27_09620	-	-	S	-	-	-	FMN reductase (NADPH) activity
NHKNCPHF_00190	8.2e-102	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NHKNCPHF_00191	4.79e-100	-	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
NHKNCPHF_00192	1.08e-287	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHKNCPHF_00193	1.02e-163	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
NHKNCPHF_00194	2.76e-115	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
NHKNCPHF_00195	1.34e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
NHKNCPHF_00196	1.69e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHKNCPHF_00197	1.37e-155	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHKNCPHF_00198	0.0	amiA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NHKNCPHF_00199	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHKNCPHF_00200	9.69e-292	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	signal transduction protein with a C-terminal ATPase domain
NHKNCPHF_00201	2.1e-193	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHKNCPHF_00202	1.16e-260	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHKNCPHF_00203	3.57e-284	fasC	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHKNCPHF_00204	9.29e-168	fasA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulator of the LytR AlgR family
NHKNCPHF_00205	3.51e-294	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHKNCPHF_00206	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase
NHKNCPHF_00207	9.69e-72	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NHKNCPHF_00208	4.24e-187	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHKNCPHF_00209	4.26e-230	jag	-	-	S	ko:K06346	-	ko00000	RNA-binding protein
NHKNCPHF_00210	1.08e-125	-	-	-	K	-	-	-	Transcriptional regulator
NHKNCPHF_00211	9.27e-127	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-quinone reductase (modulator of drug activity B)
NHKNCPHF_00212	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
NHKNCPHF_00213	1.16e-287	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHKNCPHF_00226	1.09e-68	bta	1.8.1.8	-	CO	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	cell redox homeostasis
NHKNCPHF_00227	7.13e-75	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	thioesterase
NHKNCPHF_00228	2.49e-183	-	-	-	S	-	-	-	Macro domain protein
NHKNCPHF_00229	3.11e-67	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NHKNCPHF_00230	4.11e-95	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
NHKNCPHF_00231	2.16e-181	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
NHKNCPHF_00232	2.57e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NHKNCPHF_00233	4.82e-196	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHKNCPHF_00235	3.08e-208	rsgA	3.1.3.100	-	G	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHKNCPHF_00236	1.15e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NHKNCPHF_00237	2.16e-150	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NHKNCPHF_00238	2.42e-231	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC domain protein
NHKNCPHF_00239	6.86e-228	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
NHKNCPHF_00240	1.6e-183	purR	-	-	F	ko:K09685	-	ko00000,ko03000	operon repressor
NHKNCPHF_00241	4.89e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NHKNCPHF_00242	4.66e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NHKNCPHF_00243	6.8e-291	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHKNCPHF_00244	1.41e-196	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHKNCPHF_00245	4.47e-231	gap	1.2.1.12	-	C	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
NHKNCPHF_00246	1.48e-153	-	-	-	-	-	-	-	-
NHKNCPHF_00247	2.72e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NHKNCPHF_00248	1.03e-111	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
NHKNCPHF_00249	9.18e-83	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
NHKNCPHF_00250	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NHKNCPHF_00251	4.18e-148	sle1	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	CHAP domain protein
NHKNCPHF_00252	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHKNCPHF_00253	4.54e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NHKNCPHF_00254	2.86e-147	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214, inactive homolog of metal-dependent proteases
NHKNCPHF_00255	1.42e-92	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NHKNCPHF_00256	3.86e-237	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHKNCPHF_00257	5.94e-147	XK27_12120	-	-	E	-	-	-	AzlC protein
NHKNCPHF_00258	2.69e-61	-	-	-	S	-	-	-	branched-chain amino acid
NHKNCPHF_00259	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHKNCPHF_00260	1.99e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NHKNCPHF_00261	1.85e-199	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHKNCPHF_00262	1.18e-20	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NHKNCPHF_00263	4.82e-121	cvpA	-	-	S	ko:K03558	-	ko00000	toxin biosynthetic process
NHKNCPHF_00264	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHKNCPHF_00265	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHKNCPHF_00267	4.73e-12	-	-	-	-	-	-	-	-
NHKNCPHF_00269	2.43e-286	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
NHKNCPHF_00270	3.53e-51	XK27_05745	-	-	-	-	-	-	-
NHKNCPHF_00271	5.39e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NHKNCPHF_00272	2.61e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHKNCPHF_00273	4.1e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHKNCPHF_00275	1.39e-157	XK27_01040	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NHKNCPHF_00276	2.01e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	COG0598 Mg2 and Co2 transporters
NHKNCPHF_00277	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NHKNCPHF_00281	9.66e-40	blpT	-	-	-	-	-	-	-
NHKNCPHF_00282	3.51e-185	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	'abc transporter, ATP-binding protein
NHKNCPHF_00284	4.83e-255	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
NHKNCPHF_00285	3.59e-111	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NHKNCPHF_00286	1.22e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHKNCPHF_00287	7.41e-80	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	protein conserved in bacteria
NHKNCPHF_00288	1.09e-95	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHKNCPHF_00289	1.01e-224	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	Transcriptional regulator
NHKNCPHF_00290	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NHKNCPHF_00291	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHKNCPHF_00292	2.28e-218	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Fructokinase
NHKNCPHF_00293	2.07e-239	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NHKNCPHF_00295	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHKNCPHF_00296	1.37e-249	aroH	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NHKNCPHF_00297	3.83e-249	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NHKNCPHF_00298	3.42e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHKNCPHF_00299	2.72e-243	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHKNCPHF_00300	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHKNCPHF_00304	4.07e-43	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
NHKNCPHF_00306	8.56e-217	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NHKNCPHF_00307	0.0	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
NHKNCPHF_00308	5.8e-161	yebC	-	-	M	-	-	-	Membrane
NHKNCPHF_00309	0.0	-	-	-	KT	-	-	-	response to antibiotic
NHKNCPHF_00310	8.7e-115	-	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
NHKNCPHF_00311	6.23e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
NHKNCPHF_00312	9.64e-153	-	-	-	S	-	-	-	membrane
NHKNCPHF_00313	4.86e-98	mccF	-	-	V	-	-	-	LD-carboxypeptidase
NHKNCPHF_00314	1.06e-57	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
NHKNCPHF_00315	3.11e-247	mccF	-	-	V	-	-	-	LD-carboxypeptidase
NHKNCPHF_00316	0.0	-	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
NHKNCPHF_00318	8.38e-187	-	-	-	V	ko:K21397	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
NHKNCPHF_00321	1.5e-14	-	-	-	-	-	-	-	-
NHKNCPHF_00322	6.91e-297	dcuS	2.7.13.3	-	T	ko:K02476,ko:K07701,ko:K07706,ko:K11614	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHKNCPHF_00323	2.09e-304	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHKNCPHF_00324	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NHKNCPHF_00325	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NHKNCPHF_00326	1.48e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
NHKNCPHF_00327	7.42e-172	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_00328	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NHKNCPHF_00329	9.65e-180	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHKNCPHF_00330	2.75e-286	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHKNCPHF_00331	2.67e-78	-	-	-	J	-	-	-	Membrane
NHKNCPHF_00332	7.64e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NHKNCPHF_00333	1.95e-20	-	-	-	L	ko:K07497	-	ko00000	Transposase and inactivated derivatives
NHKNCPHF_00334	2.48e-113	-	-	-	L	-	-	-	Endonuclease
NHKNCPHF_00335	3.36e-76	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
NHKNCPHF_00336	8.57e-60	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
NHKNCPHF_00339	2.14e-131	-	-	-	-	-	-	-	-
NHKNCPHF_00340	2.67e-222	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHKNCPHF_00341	5.32e-60	ftsL	-	-	D	-	-	-	cell division protein FtsL
NHKNCPHF_00342	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
NHKNCPHF_00343	3.29e-235	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHKNCPHF_00344	4.56e-303	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NHKNCPHF_00346	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NHKNCPHF_00347	3.06e-105	yutD	-	-	J	-	-	-	protein conserved in bacteria
NHKNCPHF_00348	7.84e-286	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NHKNCPHF_00349	9.45e-121	XK27_09885	-	-	V	-	-	-	Glycopeptide antibiotics resistance protein
NHKNCPHF_00352	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_00353	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_00354	9.86e-17	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
NHKNCPHF_00361	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NHKNCPHF_00362	1.24e-201	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NHKNCPHF_00363	2.29e-117	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
NHKNCPHF_00364	3.8e-179	cppA	-	-	E	-	-	-	CppA N-terminal
NHKNCPHF_00365	2.33e-213	-	-	-	V	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding proteins
NHKNCPHF_00368	9.88e-95	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHKNCPHF_00369	1.5e-184	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	carbonic anhydrase
NHKNCPHF_00370	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	formate acetyltransferase'
NHKNCPHF_00371	3.58e-260	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHKNCPHF_00373	5.46e-195	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
NHKNCPHF_00375	1.05e-193	yxeN	-	-	P	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_00376	3.11e-166	tcyN	3.6.3.21	-	E	ko:K02028,ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHKNCPHF_00377	1.48e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF4059)
NHKNCPHF_00378	1.13e-218	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHKNCPHF_00379	1.05e-119	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
NHKNCPHF_00380	5.14e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHKNCPHF_00381	1.77e-239	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NHKNCPHF_00382	2.06e-232	ytqA	-	-	S	ko:K07139	-	ko00000	radical SAM protein
NHKNCPHF_00383	3.52e-124	mraW1	-	-	J	-	-	-	(SAM)-dependent
NHKNCPHF_00385	8.49e-293	nhaP1	-	-	P	ko:K03316	-	ko00000	NhaP-type Na H and K H antiporters
NHKNCPHF_00386	4.72e-125	nhaP1	-	-	P	ko:K03316	-	ko00000	NhaP-type Na H and K H antiporters
NHKNCPHF_00387	1.64e-33	-	-	-	-	-	-	-	-
NHKNCPHF_00389	1.44e-182	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHKNCPHF_00390	7.04e-305	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	COG1253 Hemolysins and related proteins containing CBS domains
NHKNCPHF_00392	6.98e-202	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHKNCPHF_00394	6.2e-98	XK27_03180	-	-	T	-	-	-	universal stress protein
NHKNCPHF_00395	1.02e-300	aspC	2.6.1.2, 2.6.1.66	-	E	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NHKNCPHF_00396	2.12e-180	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NHKNCPHF_00397	4.12e-128	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	isochorismatase
NHKNCPHF_00398	0.0	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NHKNCPHF_00399	1.75e-275	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
NHKNCPHF_00400	1.39e-201	-	-	-	H	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
NHKNCPHF_00401	3.84e-237	-	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NHKNCPHF_00402	3.04e-293	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NHKNCPHF_00403	7.49e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHKNCPHF_00404	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHKNCPHF_00405	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHKNCPHF_00406	2.41e-84	-	-	-	-	-	-	-	-
NHKNCPHF_00407	1.31e-196	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHKNCPHF_00408	4.52e-128	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
NHKNCPHF_00409	1.09e-272	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NHKNCPHF_00410	1.86e-64	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
NHKNCPHF_00411	6.44e-152	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHKNCPHF_00412	2.64e-135	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
NHKNCPHF_00413	3.42e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHKNCPHF_00414	6.13e-177	XK27_06665	-	-	Q	-	-	-	Methyltransferase domain protein
NHKNCPHF_00415	1.53e-247	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NHKNCPHF_00417	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	ATP-dependent Clp protease ATP-binding subunit
NHKNCPHF_00418	1.83e-25	-	-	-	-	-	-	-	-
NHKNCPHF_00419	2.55e-66	-	-	-	-	-	-	-	-
NHKNCPHF_00422	3.05e-95	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NHKNCPHF_00423	1.18e-168	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_00424	1.48e-223	XK27_05910	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
NHKNCPHF_00425	2.95e-197	ytmP	-	-	M	-	-	-	Phosphotransferase
NHKNCPHF_00426	1.25e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHKNCPHF_00428	5.29e-95	-	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
NHKNCPHF_00429	1.52e-272	ytfP	-	-	S	ko:K07007	-	ko00000	Flavoprotein
NHKNCPHF_00430	0.0	ilvD	4.2.1.9	-	E	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
NHKNCPHF_00431	5.21e-82	XK27_02560	-	-	S	-	-	-	cog cog2151
NHKNCPHF_00432	5.18e-76	WQ51_02910	-	-	S	-	-	-	Protein of unknown function, DUF536
NHKNCPHF_00433	1.26e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NHKNCPHF_00434	1.95e-162	-	-	-	K	-	-	-	transcriptional regulator, MerR family
NHKNCPHF_00435	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_00436	2.75e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_00438	1.37e-41	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NHKNCPHF_00439	3.57e-60	-	-	-	-	-	-	-	-
NHKNCPHF_00440	4.96e-63	-	-	-	-	-	-	-	-
NHKNCPHF_00441	6.29e-59	-	-	-	-	-	-	-	-
NHKNCPHF_00442	7.69e-102	-	-	-	-	-	-	-	-
NHKNCPHF_00443	1.56e-114	-	-	-	-	-	-	-	-
NHKNCPHF_00444	7.71e-24	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
NHKNCPHF_00445	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
NHKNCPHF_00446	1.87e-76	-	-	-	-	-	-	-	-
NHKNCPHF_00447	3.03e-28	-	-	-	S	-	-	-	Bacteriocin (Lactococcin_972)
NHKNCPHF_00448	0.0	-	-	-	S	ko:K02004	-	ko00000,ko00002,ko02000	bacteriocin-associated integral membrane protein
NHKNCPHF_00449	6.14e-155	XK27_10210	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	lipoprotein transporter activity
NHKNCPHF_00450	1.04e-53	-	4.2.99.21	-	E	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Chorismate mutase type II
NHKNCPHF_00451	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHKNCPHF_00452	1.18e-134	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	anthranilate
NHKNCPHF_00453	7.39e-229	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NHKNCPHF_00454	2.66e-171	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
NHKNCPHF_00455	5.96e-126	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the TrpF family
NHKNCPHF_00456	1e-290	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NHKNCPHF_00457	3.54e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NHKNCPHF_00460	2.58e-98	copY	-	-	K	-	-	-	negative regulation of transcription, DNA-templated
NHKNCPHF_00461	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NHKNCPHF_00462	2.72e-42	copZ	-	-	P	-	-	-	Heavy metal-associated domain protein
NHKNCPHF_00463	1.68e-44	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
NHKNCPHF_00464	3.26e-107	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NHKNCPHF_00465	2.68e-66	-	-	-	-	-	-	-	-
NHKNCPHF_00466	1.79e-243	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NHKNCPHF_00467	1.42e-147	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_00468	6.53e-148	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_00469	3.13e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHKNCPHF_00470	1.1e-198	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NHKNCPHF_00473	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHKNCPHF_00474	1.75e-150	ywaF	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
NHKNCPHF_00475	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHKNCPHF_00476	5.34e-128	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter
NHKNCPHF_00477	1.51e-82	yjqA	-	-	S	-	-	-	Bacterial PH domain
NHKNCPHF_00478	1.1e-202	corA	-	-	P	-	-	-	CorA-like protein
NHKNCPHF_00479	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHKNCPHF_00480	6.85e-55	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
NHKNCPHF_00481	1.01e-179	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase
NHKNCPHF_00482	3.17e-203	nodB3	-	-	G	-	-	-	deacetylase
NHKNCPHF_00483	2.5e-183	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
NHKNCPHF_00484	7.27e-132	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
NHKNCPHF_00485	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NHKNCPHF_00486	5.82e-290	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHKNCPHF_00487	1.44e-127	XK27_07830	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase GNAT Family
NHKNCPHF_00488	7.45e-296	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
NHKNCPHF_00489	2.01e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NHKNCPHF_00490	1.64e-210	rbn	-	-	E	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NHKNCPHF_00491	1.71e-111	ccl	-	-	S	-	-	-	cog cog4708
NHKNCPHF_00492	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHKNCPHF_00493	1.19e-231	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NHKNCPHF_00495	3.96e-228	yfjR	-	-	K	-	-	-	regulation of single-species biofilm formation
NHKNCPHF_00497	3.21e-93	-	-	-	S	-	-	-	QueT transporter
NHKNCPHF_00498	5.11e-204	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NHKNCPHF_00500	3.53e-255	XK27_00915	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHKNCPHF_00501	1.99e-15	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
NHKNCPHF_00502	1.12e-211	tehB	2.1.1.265	-	PQ	ko:K16868	-	ko00000,ko01000	tellurite resistance protein tehb
NHKNCPHF_00503	1.74e-225	-	-	-	O	-	-	-	protein import
NHKNCPHF_00504	4.54e-158	agrA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
NHKNCPHF_00505	2.65e-268	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHKNCPHF_00507	1.87e-57	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NHKNCPHF_00508	3.71e-49	ylqC	-	-	L	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NHKNCPHF_00509	1.7e-298	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NHKNCPHF_00510	0.0	ydaO	-	-	E	-	-	-	amino acid
NHKNCPHF_00511	4.02e-129	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	gtp cyclohydrolase
NHKNCPHF_00512	1.01e-185	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NHKNCPHF_00513	0.0	amy	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NHKNCPHF_00514	1.44e-79	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NHKNCPHF_00515	3.96e-107	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NHKNCPHF_00516	3.77e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
NHKNCPHF_00517	9.28e-271	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHKNCPHF_00518	4.03e-179	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
NHKNCPHF_00519	3.07e-167	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component II
NHKNCPHF_00520	3.17e-261	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	spermidine putrescine ABC transporter
NHKNCPHF_00521	4.79e-196	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
NHKNCPHF_00522	2.36e-93	gloA	4.4.1.5	-	E	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Lactoylglutathione lyase
NHKNCPHF_00523	1.75e-202	-	-	-	GK	-	-	-	ROK family
NHKNCPHF_00524	1.47e-266	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NHKNCPHF_00525	1.62e-135	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
NHKNCPHF_00526	6.14e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHKNCPHF_00527	3.03e-84	ogt	2.1.1.63, 3.2.2.20	-	L	ko:K00567,ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
NHKNCPHF_00529	5.9e-74	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Effector of murein hydrolase LrgA
NHKNCPHF_00530	6.23e-149	lrgB	-	-	M	-	-	-	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NHKNCPHF_00531	5.25e-120	-	-	-	S	-	-	-	IA, variant 1
NHKNCPHF_00532	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHKNCPHF_00533	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHKNCPHF_00534	8.02e-144	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	phosphoserine phosphatase
NHKNCPHF_00536	2.25e-188	-	-	-	EG	-	-	-	Permeases of the drug metabolite transporter (DMT) superfamily
NHKNCPHF_00538	7.06e-81	ycaO	-	-	O	ko:K06889,ko:K07397,ko:K09136	-	ko00000,ko03009	OsmC-like protein
NHKNCPHF_00539	1.99e-82	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein possibly involved in aromatic compounds catabolism
NHKNCPHF_00540	4.89e-09	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
NHKNCPHF_00541	3.39e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NHKNCPHF_00542	9.86e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
NHKNCPHF_00543	3.8e-315	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHKNCPHF_00544	5.23e-25	XK27_00735	-	-	-	-	-	-	-
NHKNCPHF_00545	4.14e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHKNCPHF_00546	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems periplasmic component domain
NHKNCPHF_00547	6.65e-209	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
NHKNCPHF_00550	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHKNCPHF_00551	1.91e-103	XK27_04400	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	Nudix family
NHKNCPHF_00552	2.1e-180	XK27_04395	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter
NHKNCPHF_00553	2.56e-176	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NHKNCPHF_00554	5.56e-269	arcT	-	-	E	-	-	-	Aminotransferase
NHKNCPHF_00555	1.77e-169	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NHKNCPHF_00556	8.61e-28	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NHKNCPHF_00557	1.21e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHKNCPHF_00558	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHKNCPHF_00559	2.49e-256	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHKNCPHF_00560	1.43e-73	yitW	-	-	K	-	-	-	metal-sulfur cluster biosynthetic enzyme
NHKNCPHF_00561	2.18e-217	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	COG0463, glycosyltransferases involved in cell wall biogenesis
NHKNCPHF_00562	1.64e-204	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NHKNCPHF_00563	2.8e-160	-	-	-	S	-	-	-	Glycosyl transferase family 2
NHKNCPHF_00564	3.81e-64	-	-	-	S	ko:K09153	-	ko00000	Uncharacterized conserved protein (DUF2304)
NHKNCPHF_00565	2.03e-274	rgpX3	-	-	S	-	-	-	polysaccharide biosynthetic process
NHKNCPHF_00566	9.88e-163	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	transferase activity, transferring glycosyl groups
NHKNCPHF_00567	2.64e-172	-	-	-	S	-	-	-	Predicted membrane protein (DUF2142)
NHKNCPHF_00568	2.45e-271	rgpA	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
NHKNCPHF_00569	7.65e-223	rgpB	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
NHKNCPHF_00570	4.1e-182	rgpC	-	-	GM	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
NHKNCPHF_00571	2.01e-285	rgpD	3.6.3.40	-	P	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NHKNCPHF_00572	1.83e-234	rgpEc	-	GT2	M	ko:K12998	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
NHKNCPHF_00573	0.0	rgpF	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
NHKNCPHF_00574	1.32e-153	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
NHKNCPHF_00575	3.04e-165	-	-	-	T	ko:K07010	-	ko00000,ko01002	peptidase C26
NHKNCPHF_00576	1.1e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NHKNCPHF_00577	1.25e-78	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
NHKNCPHF_00578	6.45e-264	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
NHKNCPHF_00579	8.28e-225	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHKNCPHF_00580	9.61e-131	yjbK	-	-	S	-	-	-	Adenylate cyclase
NHKNCPHF_00581	1.17e-153	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Gtp pyrophosphokinase
NHKNCPHF_00582	1.63e-195	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHKNCPHF_00583	2.46e-218	yjbO	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NHKNCPHF_00584	2.78e-225	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
NHKNCPHF_00585	0.0	amiA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NHKNCPHF_00586	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NHKNCPHF_00587	0.0	amiC	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_00588	3.18e-210	amiD	-	-	P	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_00589	9.41e-257	amiE	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHKNCPHF_00590	7.05e-219	amiF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHKNCPHF_00591	9.09e-166	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
NHKNCPHF_00592	1.18e-158	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_00593	8.13e-82	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional
NHKNCPHF_00594	9.05e-188	-	-	-	S	-	-	-	overlaps another CDS with the same product name
NHKNCPHF_00595	1.01e-188	XK27_02985	-	-	S	-	-	-	overlaps another CDS with the same product name
NHKNCPHF_00596	1.76e-277	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHKNCPHF_00597	4.34e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NHKNCPHF_00598	2.28e-60	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-directed 5'-3' RNA polymerase activity
NHKNCPHF_00599	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHKNCPHF_00600	2.36e-218	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHKNCPHF_00601	1.28e-311	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHKNCPHF_00602	2.57e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NHKNCPHF_00603	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NHKNCPHF_00604	2.42e-141	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
NHKNCPHF_00605	2.86e-150	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Membrane
NHKNCPHF_00606	2.42e-219	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHKNCPHF_00607	2.7e-146	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHKNCPHF_00610	9.14e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHKNCPHF_00611	1.98e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NHKNCPHF_00612	7.82e-239	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NHKNCPHF_00613	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NHKNCPHF_00614	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
NHKNCPHF_00615	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NHKNCPHF_00616	2.18e-251	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NHKNCPHF_00617	2.81e-230	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	glucose-1-phosphate adenylyltransferase
NHKNCPHF_00618	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
NHKNCPHF_00619	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NHKNCPHF_00620	1.49e-127	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
NHKNCPHF_00621	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
NHKNCPHF_00623	0.0	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
NHKNCPHF_00624	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
NHKNCPHF_00625	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
NHKNCPHF_00626	4.17e-240	XK27_10075	-	-	S	-	-	-	abc transporter atp-binding protein
NHKNCPHF_00627	2.29e-09	-	-	-	-	-	-	-	-
NHKNCPHF_00628	0.0	-	-	-	M	-	-	-	domain protein
NHKNCPHF_00629	1.72e-303	-	-	-	M	-	-	-	Rib/alpha-like repeat
NHKNCPHF_00630	0.0	-	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	signal peptide protein, YSIRK family
NHKNCPHF_00631	0.0	-	-	-	GM	-	-	-	domain, Protein
NHKNCPHF_00632	2.13e-276	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NHKNCPHF_00633	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	ATPase involved in DNA repair
NHKNCPHF_00634	0.0	-	-	-	M	-	-	-	family 8
NHKNCPHF_00635	2.01e-268	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the accessory SecA2 SecY2 system specifically required for export of
NHKNCPHF_00636	0.0	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
NHKNCPHF_00637	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system protein Asp2
NHKNCPHF_00638	8.2e-102	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec system protein Asp3
NHKNCPHF_00639	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHKNCPHF_00640	0.0	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NHKNCPHF_00641	1.39e-310	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NHKNCPHF_00642	3.27e-24	-	-	-	S	-	-	-	Accessory secretory protein Sec Asp4
NHKNCPHF_00643	3.67e-23	-	-	-	S	-	-	-	Accessory secretory protein Sec, Asp5
NHKNCPHF_00644	2.42e-238	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NHKNCPHF_00645	0.0	sraP	-	-	UW	ko:K18491,ko:K21449	ko04550,map04550	ko00000,ko00001,ko02000,ko03000	Hep Hag repeat protein
NHKNCPHF_00646	3.06e-87	sraP	-	-	UW	ko:K18491,ko:K21449	ko04550,map04550	ko00000,ko00001,ko02000,ko03000	Hep Hag repeat protein
NHKNCPHF_00651	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
NHKNCPHF_00652	0.0	-	3.5.1.28	-	M	ko:K01448,ko:K13733,ko:K20276	ko01503,ko02024,ko05100,map01503,map02024,map05100	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	domain protein
NHKNCPHF_00653	2.21e-176	-	-	-	S	-	-	-	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
NHKNCPHF_00654	6.98e-127	maa	2.3.1.79	-	GK	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
NHKNCPHF_00655	5.96e-87	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NHKNCPHF_00656	1.36e-302	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major facilitator Superfamily
NHKNCPHF_00657	1.81e-172	-	-	-	S	-	-	-	CAAX protease self-immunity
NHKNCPHF_00659	2.21e-289	-	-	-	S	-	-	-	dextransucrase activity
NHKNCPHF_00660	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
NHKNCPHF_00661	0.0	-	-	-	S	-	-	-	dextransucrase activity
NHKNCPHF_00662	3.6e-242	-	-	-	S	-	-	-	dextransucrase activity
NHKNCPHF_00663	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
NHKNCPHF_00664	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
NHKNCPHF_00665	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
NHKNCPHF_00666	2.91e-200	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NHKNCPHF_00667	2.16e-130	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NHKNCPHF_00668	1.54e-96	-	-	-	-	-	-	-	-
NHKNCPHF_00669	0.0	-	-	-	S	-	-	-	dextransucrase activity
NHKNCPHF_00670	5.98e-101	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
NHKNCPHF_00671	0.0	-	-	-	S	-	-	-	dextransucrase activity
NHKNCPHF_00672	6.41e-285	-	-	-	S	-	-	-	dextransucrase activity
NHKNCPHF_00673	0.0	-	-	-	S	-	-	-	dextransucrase activity
NHKNCPHF_00674	2.58e-110	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
NHKNCPHF_00675	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
NHKNCPHF_00676	0.0	-	-	-	S	-	-	-	dextransucrase activity
NHKNCPHF_00678	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
NHKNCPHF_00679	2.43e-10	-	-	-	S	-	-	-	Enterocin A Immunity
NHKNCPHF_00680	5.08e-65	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NHKNCPHF_00681	2.82e-139	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
NHKNCPHF_00682	7.02e-58	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NHKNCPHF_00683	2.77e-15	-	-	-	S	-	-	-	integral membrane protein
NHKNCPHF_00684	1.17e-246	mccF	-	-	V	-	-	-	LD-carboxypeptidase
NHKNCPHF_00685	6.93e-13	-	-	-	S	-	-	-	Enterocin A Immunity
NHKNCPHF_00686	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NHKNCPHF_00687	7.25e-46	-	-	-	S	-	-	-	Immunity protein 41
NHKNCPHF_00688	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
NHKNCPHF_00689	1.27e-289	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
NHKNCPHF_00690	4.12e-228	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dihydroxyacetone kinase
NHKNCPHF_00691	7.81e-121	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dihydroxyacetone kinase
NHKNCPHF_00692	2e-77	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	dihydroxyacetone kinase, phosphotransfer subunit
NHKNCPHF_00693	1.34e-232	XK27_10475	-	-	S	-	-	-	oxidoreductase
NHKNCPHF_00694	9.96e-41	-	-	-	P	-	-	-	oxidoreductase
NHKNCPHF_00695	6.28e-203	-	-	-	P	-	-	-	oxidoreductase
NHKNCPHF_00696	1.5e-115	-	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
NHKNCPHF_00697	1.6e-69	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
NHKNCPHF_00698	1.39e-83	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
NHKNCPHF_00699	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Domain of unknown function DUF87
NHKNCPHF_00700	1.82e-297	-	-	-	K	ko:K07467	-	ko00000	Replication initiation factor
NHKNCPHF_00701	3.41e-41	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHKNCPHF_00702	1.42e-117	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
NHKNCPHF_00703	5.98e-116	-	-	-	S	-	-	-	TcpE family
NHKNCPHF_00704	0.0	-	-	-	S	-	-	-	AAA-like domain
NHKNCPHF_00705	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHKNCPHF_00706	3.21e-243	-	-	-	M	-	-	-	NlpC p60 family protein
NHKNCPHF_00707	8.14e-217	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
NHKNCPHF_00708	0.0	XK27_03330	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	elongation factor G
NHKNCPHF_00709	1.28e-173	ermA	2.1.1.184	-	J	ko:K00561	-	br01600,ko00000,ko01000,ko01504,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
NHKNCPHF_00710	4.63e-24	-	-	-	-	-	-	-	-
NHKNCPHF_00711	1.67e-123	-	-	-	L	-	-	-	Resolvase, N terminal domain
NHKNCPHF_00712	0.0	-	-	-	L	-	-	-	Transposase and inactivated derivatives, TnpA family
NHKNCPHF_00713	2.99e-49	-	-	-	K	-	-	-	Helix-turn-helix domain
NHKNCPHF_00714	3.84e-94	-	-	-	K	-	-	-	Sigma-70, region 4
NHKNCPHF_00715	1.4e-48	-	-	-	S	-	-	-	Helix-turn-helix domain
NHKNCPHF_00716	3.87e-42	xis	-	-	S	-	-	-	Excisionase from transposon Tn916
NHKNCPHF_00717	8.33e-296	-	-	-	L	-	-	-	DNA binding domain of tn916 integrase
NHKNCPHF_00718	2.14e-06	-	-	-	-	-	-	-	-
NHKNCPHF_00719	0.0	XK27_07020	-	-	S	-	-	-	Belongs to the UPF0371 family
NHKNCPHF_00720	2.44e-270	vex1	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
NHKNCPHF_00721	2.05e-139	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_00722	9.21e-304	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
NHKNCPHF_00723	1.06e-149	vncR	-	-	K	-	-	-	Response regulator receiver domain protein
NHKNCPHF_00724	5.78e-288	vncS	2.7.13.3	-	T	ko:K10819	-	ko00000,ko01000	Histidine kinase
NHKNCPHF_00725	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	COG0366 Glycosidases
NHKNCPHF_00726	1.87e-194	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NHKNCPHF_00727	2.83e-283	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHKNCPHF_00728	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDPglucose--hexose-1-phosphate uridylyltransferase
NHKNCPHF_00729	1e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NHKNCPHF_00730	8.98e-253	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NHKNCPHF_00731	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	transporter
NHKNCPHF_00732	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
NHKNCPHF_00733	1.54e-271	-	-	-	S	-	-	-	Tetratricopeptide repeat
NHKNCPHF_00734	5.94e-201	yvgN	-	-	C	-	-	-	reductase
NHKNCPHF_00735	4.22e-41	XK27_10490	-	-	-	-	-	-	-
NHKNCPHF_00736	4.6e-53	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	nuclease activity
NHKNCPHF_00737	1.07e-143	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NHKNCPHF_00738	5.87e-139	yodC	-	-	C	-	-	-	nitroreductase
NHKNCPHF_00739	1.92e-284	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHKNCPHF_00740	3.99e-198	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NHKNCPHF_00741	7.28e-101	ywnA_2	-	-	K	-	-	-	Transcriptional regulator
NHKNCPHF_00742	1.85e-202	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
NHKNCPHF_00743	6.45e-138	XK27_02070	-	-	S	ko:K07078	-	ko00000	nitroreductase
NHKNCPHF_00744	2.46e-218	ydhF	-	-	S	-	-	-	Aldo keto reductase
NHKNCPHF_00745	1.32e-125	-	-	-	K	-	-	-	WHG domain
NHKNCPHF_00746	4.3e-158	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_00747	3.66e-255	-	-	-	P	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHKNCPHF_00748	1.39e-56	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
NHKNCPHF_00749	8.69e-107	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
NHKNCPHF_00750	0.0	-	-	-	S	-	-	-	dextransucrase activity
NHKNCPHF_00751	7.38e-284	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
NHKNCPHF_00752	1.7e-66	-	-	-	S	-	-	-	ASCH
NHKNCPHF_00753	1.07e-271	-	-	-	S	-	-	-	Carbohydrate-binding domain-containing protein Cthe_2159
NHKNCPHF_00754	1.3e-32	-	-	-	S	-	-	-	CsbD-like
NHKNCPHF_00755	2.29e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
NHKNCPHF_00756	1.7e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
NHKNCPHF_00757	5.88e-229	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NHKNCPHF_00758	1.95e-290	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NHKNCPHF_00759	5.67e-232	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHKNCPHF_00761	3.15e-311	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
NHKNCPHF_00762	5.58e-184	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
NHKNCPHF_00763	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	(ABC) transporter
NHKNCPHF_00764	4.2e-284	pbuX	-	-	F	ko:K16169	-	ko00000,ko02000	xanthine permease
NHKNCPHF_00765	2.08e-126	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHKNCPHF_00766	3.02e-39	-	-	-	-	-	-	-	-
NHKNCPHF_00767	5.24e-159	graR	-	-	KT	ko:K19082	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHKNCPHF_00768	1.25e-199	-	-	-	T	-	-	-	Histidine kinase
NHKNCPHF_00769	2.87e-169	yxdL	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NHKNCPHF_00770	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
NHKNCPHF_00771	1.17e-120	XK27_05000	-	-	S	ko:K06940	-	ko00000	metal cluster binding
NHKNCPHF_00774	5.44e-199	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_00775	2.81e-152	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transporter
NHKNCPHF_00776	4.93e-108	-	-	-	F	-	-	-	cytidine deaminase activity
NHKNCPHF_00777	3.83e-208	yocS	-	-	S	ko:K03453	-	ko00000	Transporter
NHKNCPHF_00778	0.0	hscC	-	-	O	ko:K04045	-	ko00000,ko03110	Belongs to the heat shock protein 70 family
NHKNCPHF_00779	1.44e-262	anK3	-	-	G	ko:K07126	-	ko00000	response to abiotic stimulus
NHKNCPHF_00783	1.52e-205	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_00784	2.04e-170	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NHKNCPHF_00785	4.86e-240	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHKNCPHF_00786	1.99e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHKNCPHF_00787	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
NHKNCPHF_00788	6.69e-239	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_00789	5.16e-182	M1-956	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHKNCPHF_00790	1.1e-182	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHKNCPHF_00791	0.000123	-	-	-	-	-	-	-	-
NHKNCPHF_00792	9.26e-110	-	-	-	-	-	-	-	-
NHKNCPHF_00793	6.31e-60	-	-	-	-	-	-	-	-
NHKNCPHF_00794	8.06e-104	-	-	-	S	-	-	-	RDD family
NHKNCPHF_00795	2.18e-101	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NHKNCPHF_00796	1.82e-189	-	-	-	S	-	-	-	Protein of unknown function DUF262
NHKNCPHF_00797	4.45e-250	-	-	-	S	-	-	-	Protein of unknown function DUF262
NHKNCPHF_00798	7e-168	-	-	-	L	ko:K07482	-	ko00000	Integrase
NHKNCPHF_00799	0.0	-	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NHKNCPHF_00800	9.5e-275	-	-	-	GKT	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHKNCPHF_00801	1.45e-56	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system galactitol-specific IIB component
NHKNCPHF_00802	3.67e-282	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NHKNCPHF_00803	3.85e-156	tktN	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose-5-phosphate synthase
NHKNCPHF_00804	3.89e-156	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
NHKNCPHF_00805	1.31e-188	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
NHKNCPHF_00806	9.02e-154	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
NHKNCPHF_00807	4.98e-24	yfnB	3.8.1.2	-	E	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	hydrolase
NHKNCPHF_00808	1.3e-126	yfnB	3.8.1.2	-	E	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	hydrolase
NHKNCPHF_00809	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHKNCPHF_00810	9e-48	-	-	-	P	ko:K10716	-	ko00000,ko02000	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NHKNCPHF_00811	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
NHKNCPHF_00812	2.27e-192	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NHKNCPHF_00813	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHKNCPHF_00814	8.38e-113	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase
NHKNCPHF_00815	0.0	clsA_1	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHKNCPHF_00816	2.24e-160	-	-	-	L	-	-	-	DNA alkylation repair enzyme
NHKNCPHF_00817	2.49e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHKNCPHF_00818	1.81e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHKNCPHF_00819	1.25e-158	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHKNCPHF_00820	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NHKNCPHF_00821	2.03e-118	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
NHKNCPHF_00822	7.46e-32	WQ51_00220	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
NHKNCPHF_00823	7.97e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHKNCPHF_00824	1.2e-117	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHKNCPHF_00825	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHKNCPHF_00827	6.52e-75	nrdD_1	1.1.98.6, 1.17.4.1	-	F	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleoside-triphosphate reductase
NHKNCPHF_00828	8.14e-302	ycxD	-	-	K	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHKNCPHF_00830	4.02e-110	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NHKNCPHF_00831	6.43e-203	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Belongs to the pyridoxine kinase family
NHKNCPHF_00832	9.69e-110	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NHKNCPHF_00833	0.0	yheS_1	-	-	S	-	-	-	abc transporter atp-binding protein
NHKNCPHF_00834	7.23e-291	noxE	-	-	P	-	-	-	NADH oxidase
NHKNCPHF_00835	2.92e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NHKNCPHF_00836	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHKNCPHF_00837	3.1e-169	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
NHKNCPHF_00838	3.16e-95	ywkD	-	-	E	ko:K08234	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
NHKNCPHF_00839	2.21e-208	ypuA	-	-	S	-	-	-	secreted protein
NHKNCPHF_00840	1.82e-293	mntH_2	-	-	P	-	-	-	Mn2 and Fe2 transporters of the NRAMP family
NHKNCPHF_00841	3.52e-61	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
NHKNCPHF_00842	1.95e-221	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NHKNCPHF_00843	5.01e-226	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
NHKNCPHF_00844	1.77e-193	gst	-	-	O	ko:K11209	-	ko00000,ko01000	Glutathione S-transferase
NHKNCPHF_00845	8.06e-234	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NHKNCPHF_00846	6e-142	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NHKNCPHF_00847	4.58e-247	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHKNCPHF_00848	3.6e-180	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHKNCPHF_00849	4.22e-127	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHKNCPHF_00850	3.13e-292	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHKNCPHF_00851	3.67e-229	-	-	-	S	-	-	-	37-kD nucleoid-associated bacterial protein
NHKNCPHF_00852	1.77e-127	pvaA	-	-	M	ko:K02395	-	ko00000,ko02035	lytic transglycosylase activity
NHKNCPHF_00853	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
NHKNCPHF_00854	0.0	XK27_10035	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
NHKNCPHF_00855	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHKNCPHF_00856	2.07e-301	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Membrane protein involved in D-alanine export
NHKNCPHF_00857	7.07e-48	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHKNCPHF_00858	1.17e-306	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NHKNCPHF_00859	0.0	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
NHKNCPHF_00860	0.0	pabB	2.6.1.85, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	ko00000,ko00001,ko01000,ko01007	component I
NHKNCPHF_00862	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NHKNCPHF_00863	4.05e-209	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	reductase
NHKNCPHF_00864	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
NHKNCPHF_00865	1.24e-119	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NHKNCPHF_00866	1.43e-118	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHKNCPHF_00867	2.77e-150	coaB	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	Phosphopantothenate-cysteine ligase
NHKNCPHF_00868	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
NHKNCPHF_00869	2.39e-154	ciaR	-	-	T	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHKNCPHF_00870	7.11e-310	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHKNCPHF_00871	4.36e-40	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NHKNCPHF_00872	1.55e-219	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NHKNCPHF_00873	3.21e-136	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase small domain protein
NHKNCPHF_00874	1.89e-294	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NHKNCPHF_00875	5.82e-144	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NHKNCPHF_00876	5.17e-86	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NHKNCPHF_00877	7.49e-240	-	-	-	S	ko:K07335	-	ko00000	membrane
NHKNCPHF_00878	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NHKNCPHF_00879	1.53e-243	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHKNCPHF_00880	5.77e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHKNCPHF_00881	1.76e-145	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
NHKNCPHF_00882	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NHKNCPHF_00883	2.2e-105	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
NHKNCPHF_00884	6.82e-273	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NHKNCPHF_00885	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NHKNCPHF_00887	9.11e-84	aldR	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
NHKNCPHF_00888	6.43e-160	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NHKNCPHF_00889	7.04e-107	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
NHKNCPHF_00890	1.51e-173	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NHKNCPHF_00891	5.6e-123	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NHKNCPHF_00892	9.99e-289	-	-	-	D	-	-	-	nuclear chromosome segregation
NHKNCPHF_00893	1.48e-173	yejC	-	-	S	-	-	-	cyclic nucleotide-binding protein
NHKNCPHF_00894	9.9e-208	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NHKNCPHF_00895	5.25e-233	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NHKNCPHF_00896	6.93e-207	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NHKNCPHF_00897	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NHKNCPHF_00898	2.12e-186	XK27_10720	-	-	D	-	-	-	peptidase activity
NHKNCPHF_00899	0.0	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NHKNCPHF_00902	3.25e-212	yeiH	-	-	S	-	-	-	Membrane
NHKNCPHF_00903	9.73e-165	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	muramidase
NHKNCPHF_00904	5.13e-213	cpsY	-	-	K	-	-	-	Transcriptional regulator
NHKNCPHF_00905	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHKNCPHF_00906	7.1e-78	phnA	-	-	P	ko:K06193	ko01120,map01120	ko00000	Alkylphosphonate utilization operon protein PhnA
NHKNCPHF_00907	4.78e-135	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_00908	7.5e-146	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHKNCPHF_00909	4.34e-200	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NHKNCPHF_00910	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHKNCPHF_00911	2.83e-58	-	-	-	-	-	-	-	-
NHKNCPHF_00912	9.91e-241	adhP	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NHKNCPHF_00913	2.97e-131	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NHKNCPHF_00914	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NHKNCPHF_00915	5.22e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
NHKNCPHF_00916	3.35e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHKNCPHF_00917	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHKNCPHF_00918	1.33e-111	-	-	-	-	ko:K16788	-	ko00000,ko02000	-
NHKNCPHF_00919	2.73e-118	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
NHKNCPHF_00920	2.14e-164	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
NHKNCPHF_00921	5.71e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHKNCPHF_00922	7.05e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHKNCPHF_00923	2.24e-209	-	-	-	GK	-	-	-	ROK family
NHKNCPHF_00924	1.35e-201	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
NHKNCPHF_00925	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHKNCPHF_00926	1.71e-105	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NHKNCPHF_00927	1.32e-68	-	-	-	V	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
NHKNCPHF_00929	2.19e-184	-	-	-	S	-	-	-	TraX protein
NHKNCPHF_00930	1.56e-152	yycF1	-	-	T	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHKNCPHF_00931	2.13e-289	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
NHKNCPHF_00932	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NHKNCPHF_00933	2.71e-285	XK27_05470	-	-	E	-	-	-	Methionine synthase
NHKNCPHF_00934	1.8e-94	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NHKNCPHF_00935	1.08e-57	-	-	-	P	-	-	-	Rhodanese-like protein
NHKNCPHF_00936	2.2e-174	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Acetoin reductase
NHKNCPHF_00938	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHKNCPHF_00941	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NHKNCPHF_00942	7.74e-172	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
NHKNCPHF_00943	1.29e-85	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NHKNCPHF_00944	1.66e-190	-	-	-	C	-	-	-	alcohol dehydrogenase
NHKNCPHF_00945	8.14e-163	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_00946	0.0	proWX	-	-	P	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NHKNCPHF_00947	1.59e-173	-	-	-	S	-	-	-	Phenazine biosynthesis protein
NHKNCPHF_00948	8.69e-127	-	2.7.7.65	-	T	ko:K16923,ko:K18967	-	ko00000,ko00002,ko01000,ko02000	phosphorelay sensor kinase activity
NHKNCPHF_00949	1.46e-168	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
NHKNCPHF_00950	7.23e-201	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHKNCPHF_00951	2.32e-191	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Zeta toxin
NHKNCPHF_00952	8.4e-145	-	-	-	L	ko:K07498	-	ko00000	DDE domain
NHKNCPHF_00954	1e-90	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
NHKNCPHF_00955	9.39e-123	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
NHKNCPHF_00956	4.3e-202	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
NHKNCPHF_00957	3.41e-252	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
NHKNCPHF_00958	1.02e-236	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
NHKNCPHF_00959	1.37e-307	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHKNCPHF_00960	1.24e-141	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
NHKNCPHF_00961	0.0	-	-	-	V	-	-	-	Type III restriction enzyme, res subunit
NHKNCPHF_00962	1.18e-228	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
NHKNCPHF_00963	6.82e-293	dinF	-	-	V	-	-	-	Mate efflux family protein
NHKNCPHF_00964	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHKNCPHF_00965	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
NHKNCPHF_00966	1.45e-169	-	-	-	S	-	-	-	TraX protein
NHKNCPHF_00967	9.69e-122	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
NHKNCPHF_00968	7.71e-186	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NHKNCPHF_00969	2.29e-224	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHKNCPHF_00970	5.13e-126	-	-	-	-	-	-	-	-
NHKNCPHF_00971	2.05e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NHKNCPHF_00972	1.24e-144	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHKNCPHF_00973	1.06e-301	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
NHKNCPHF_00974	7.99e-191	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NHKNCPHF_00975	3.26e-105	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_00976	0.0	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NHKNCPHF_00977	2.72e-225	bglC	-	-	K	-	-	-	Transcriptional regulator
NHKNCPHF_00978	8.07e-313	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NHKNCPHF_00979	1.43e-306	agcS	-	-	E	ko:K03310	-	ko00000	(Alanine) symporter
NHKNCPHF_00980	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NHKNCPHF_00981	1.34e-303	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
NHKNCPHF_00982	5.67e-180	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NHKNCPHF_00983	1.37e-110	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NHKNCPHF_00984	2.33e-143	hsdS2	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
NHKNCPHF_00985	3.56e-47	M1-755	-	-	P	ko:K09155	-	ko00000	Hemerythrin HHE cation binding domain protein
NHKNCPHF_00986	3.79e-307	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
NHKNCPHF_00987	1.5e-188	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHKNCPHF_00988	1.93e-213	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NHKNCPHF_00989	3.58e-93	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHKNCPHF_00990	4.17e-60	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NHKNCPHF_00991	3.26e-184	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
NHKNCPHF_00992	1.81e-308	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
NHKNCPHF_00993	3.28e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	phosphate
NHKNCPHF_00994	1.33e-200	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NHKNCPHF_00995	4.43e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate transport system permease
NHKNCPHF_00996	8.74e-192	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHKNCPHF_00997	1.5e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHKNCPHF_00998	5.43e-148	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NHKNCPHF_00999	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
NHKNCPHF_01000	3.75e-248	xerS	-	-	D	ko:K04763	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NHKNCPHF_01001	2.07e-237	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NHKNCPHF_01004	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NHKNCPHF_01005	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
NHKNCPHF_01006	1.33e-199	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NHKNCPHF_01007	1.6e-289	malX	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NHKNCPHF_01008	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_01009	2.6e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_01010	4.77e-270	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHKNCPHF_01011	5.19e-31	-	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NHKNCPHF_01012	1.24e-154	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NHKNCPHF_01013	0.0	ywbL	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
NHKNCPHF_01014	3.52e-295	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	peroxidase
NHKNCPHF_01015	1.88e-193	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
NHKNCPHF_01016	0.0	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
NHKNCPHF_01017	0.0	amiA	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-Acetylmuramoyl-L-alanine amidase
NHKNCPHF_01018	0.0	-	3.5.1.28	-	S	ko:K01448,ko:K02395,ko:K21471	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036	dextransucrase activity
NHKNCPHF_01019	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
NHKNCPHF_01020	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NHKNCPHF_01021	9.77e-276	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHKNCPHF_01022	6.61e-231	acoB	1.2.4.1	-	C	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHKNCPHF_01023	1.02e-234	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NHKNCPHF_01024	4.98e-262	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHKNCPHF_01025	4.09e-290	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHKNCPHF_01026	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHKNCPHF_01027	1.4e-298	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHKNCPHF_01028	5.24e-150	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHKNCPHF_01029	6.35e-276	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHKNCPHF_01030	3.15e-315	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
NHKNCPHF_01031	5.58e-230	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
NHKNCPHF_01032	3.56e-199	-	-	-	S	-	-	-	Phospholipase, patatin family
NHKNCPHF_01033	6.53e-132	-	-	-	E	-	-	-	Lysophospholipase L1 and related esterases
NHKNCPHF_01034	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	unusual protein kinase
NHKNCPHF_01035	2.35e-52	-	-	-	S	-	-	-	granule-associated protein
NHKNCPHF_01036	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NHKNCPHF_01037	4.4e-250	XK27_12525	-	-	S	-	-	-	hmm pf01594
NHKNCPHF_01038	8.03e-141	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NHKNCPHF_01039	7.51e-138	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NHKNCPHF_01040	9.54e-140	XK27_06100	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NHKNCPHF_01041	2.69e-130	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NHKNCPHF_01042	3.15e-48	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NHKNCPHF_01044	3.11e-229	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NHKNCPHF_01045	2.67e-274	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NHKNCPHF_01046	5.83e-309	wzx	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NHKNCPHF_01047	2.77e-136	cps3F	-	-	-	-	-	-	-
NHKNCPHF_01048	6.99e-178	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NHKNCPHF_01049	1.2e-179	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
NHKNCPHF_01050	1.51e-149	-	-	-	M	-	-	-	Domain of unknown function (DUF1919)
NHKNCPHF_01051	3.91e-244	-	-	-	M	-	-	-	Stealth protein CR3, conserved region 3
NHKNCPHF_01052	2.46e-269	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
NHKNCPHF_01053	8.13e-284	rgpAc	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	group 1 family protein
NHKNCPHF_01054	0.0	cpsE	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NHKNCPHF_01055	3.16e-154	cpsD	-	-	D	-	-	-	COG0489 ATPases involved in chromosome partitioning
NHKNCPHF_01056	2.07e-142	capA	-	-	M	-	-	-	biosynthesis protein
NHKNCPHF_01057	7.12e-170	cpsB	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	Capsular polysaccharide biosynthesis protein
NHKNCPHF_01058	1.24e-313	cps4A	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NHKNCPHF_01059	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine nucleoside phosphorylase
NHKNCPHF_01060	2.7e-171	gat	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine amidotransferase
NHKNCPHF_01061	5.34e-225	-	-	-	P	-	-	-	Chloride transporter, ClC family
NHKNCPHF_01062	8.38e-191	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NHKNCPHF_01063	2.69e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF1697)
NHKNCPHF_01064	3.53e-296	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NHKNCPHF_01065	1.18e-155	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NHKNCPHF_01066	0.0	-	-	-	V	ko:K13732	ko05100,map05100	ko00000,ko00001	Glucan-binding protein C
NHKNCPHF_01067	0.0	-	-	-	V	-	-	-	Glucan-binding protein C
NHKNCPHF_01068	6.03e-140	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
NHKNCPHF_01069	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Dipeptidase
NHKNCPHF_01070	1.38e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
NHKNCPHF_01071	5.49e-119	yybC	-	-	-	-	-	-	-
NHKNCPHF_01072	2.55e-108	XK27_03610	-	-	K	-	-	-	Gnat family
NHKNCPHF_01073	1.82e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHKNCPHF_01074	2.36e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NHKNCPHF_01075	1.1e-115	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHKNCPHF_01076	2.79e-154	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NHKNCPHF_01077	1.28e-31	XK27_09115	-	-	M	-	-	-	LysM domain
NHKNCPHF_01078	6.26e-115	ebsA	-	-	S	-	-	-	Family of unknown function (DUF5322)
NHKNCPHF_01079	1.73e-289	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NHKNCPHF_01080	0.0	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
NHKNCPHF_01081	9.3e-126	sipC	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NHKNCPHF_01082	2.64e-285	XK27_05225	-	-	G	-	-	-	COG0457 FOG TPR repeat
NHKNCPHF_01083	3.84e-235	XK27_05220	-	-	S	-	-	-	permease
NHKNCPHF_01084	1.68e-118	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NTP pyrophosphohydrolases including oxidative damage repair enzymes
NHKNCPHF_01085	3.44e-210	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NHKNCPHF_01086	8.67e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
NHKNCPHF_01087	1.08e-231	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHKNCPHF_01088	4.75e-267	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NHKNCPHF_01089	4.26e-195	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NHKNCPHF_01090	6.05e-169	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NHKNCPHF_01091	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	cation transport ATPase
NHKNCPHF_01092	2.05e-90	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
NHKNCPHF_01093	1.16e-186	XK27_00115	-	-	K	-	-	-	Acetyltransferase GNAT family
NHKNCPHF_01094	1.89e-187	XK27_00835	-	-	S	-	-	-	hydrolases of the HAD superfamily
NHKNCPHF_01095	2.76e-289	femX	2.3.2.10, 2.3.2.16	-	V	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
NHKNCPHF_01096	6.33e-74	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
NHKNCPHF_01097	2.52e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Metal-dependent hydrolases of the beta-lactamase superfamily I
NHKNCPHF_01098	8.53e-281	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHKNCPHF_01099	1.44e-165	yycF	-	-	KT	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHKNCPHF_01100	2.58e-178	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHKNCPHF_01101	1.82e-189	peb1A	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
NHKNCPHF_01102	8.31e-159	XK27_07620	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_01103	1.75e-143	-	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
NHKNCPHF_01104	1.82e-178	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHKNCPHF_01105	6.79e-185	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NHKNCPHF_01106	8.31e-159	XK27_07620	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_01107	1.75e-143	-	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
NHKNCPHF_01108	1.43e-194	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
NHKNCPHF_01109	2.03e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
NHKNCPHF_01110	8.37e-296	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHKNCPHF_01111	1.1e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
NHKNCPHF_01112	7.06e-249	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NHKNCPHF_01113	7.16e-166	-	-	-	G	-	-	-	Domain of unknown function (DUF4832)
NHKNCPHF_01114	2.28e-108	-	-	-	S	-	-	-	membrane
NHKNCPHF_01115	3.46e-122	-	-	-	P	-	-	-	VTC domain
NHKNCPHF_01116	5.95e-280	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
NHKNCPHF_01117	2.44e-239	-	-	-	M	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
NHKNCPHF_01118	0.0	-	2.4.1.52	GT4	M	ko:K00712,ko:K21011	ko02025,map02025	ko00000,ko00001,ko01000,ko01003	Domain of unknown function (DUF3492)
NHKNCPHF_01119	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
NHKNCPHF_01120	1.38e-184	-	-	-	-	-	-	-	-
NHKNCPHF_01121	0.0	-	5.1.3.2	-	GM	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	ko00000,ko00001,ko00002,ko01000	Psort location CytoplasmicMembrane, score
NHKNCPHF_01122	1.21e-268	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHKNCPHF_01123	6.82e-223	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHKNCPHF_01124	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHKNCPHF_01125	9.17e-116	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
NHKNCPHF_01126	1.2e-207	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHKNCPHF_01127	9.42e-28	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
NHKNCPHF_01130	2.33e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHKNCPHF_01131	6.45e-267	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter ClC family
NHKNCPHF_01132	4.8e-51	pheA	1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5	-	E	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
NHKNCPHF_01133	0.0	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter, ClC family
NHKNCPHF_01134	2.45e-98	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NHKNCPHF_01135	7.17e-26	XK27_08880	-	-	-	-	-	-	-
NHKNCPHF_01136	8.94e-162	XK27_08875	-	-	O	-	-	-	Zinc-dependent metalloprotease
NHKNCPHF_01137	4.17e-191	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Esterase
NHKNCPHF_01138	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHKNCPHF_01139	9.34e-175	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_01140	1.37e-190	XK27_08840	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHKNCPHF_01141	6.84e-229	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
NHKNCPHF_01143	0.0	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHKNCPHF_01144	1.91e-33	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHKNCPHF_01145	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NHKNCPHF_01146	1.29e-236	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NHKNCPHF_01147	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NHKNCPHF_01148	5.58e-146	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHKNCPHF_01149	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHKNCPHF_01150	2e-49	ysdA	-	-	L	-	-	-	Membrane
NHKNCPHF_01151	2.73e-241	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NHKNCPHF_01152	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NHKNCPHF_01153	2.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHKNCPHF_01154	4.13e-228	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
NHKNCPHF_01156	3.1e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHKNCPHF_01157	5.31e-123	ypmS	-	-	S	-	-	-	Protein conserved in bacteria
NHKNCPHF_01158	3.72e-205	XK27_03630	-	-	E	-	-	-	COG2755 Lysophospholipase L1 and related esterases
NHKNCPHF_01159	9.2e-184	WQ51_01275	-	-	S	-	-	-	DegV family
NHKNCPHF_01160	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NHKNCPHF_01161	5.12e-96	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NHKNCPHF_01162	4.46e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NHKNCPHF_01163	2.79e-195	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NHKNCPHF_01164	2.44e-40	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHKNCPHF_01165	7.29e-296	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHKNCPHF_01167	9.12e-154	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHKNCPHF_01168	1.05e-161	dnaD	-	-	-	ko:K02086	-	ko00000	-
NHKNCPHF_01169	4.86e-233	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHKNCPHF_01170	3.06e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHKNCPHF_01171	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease recj
NHKNCPHF_01172	4.06e-84	GnaT	2.5.1.16	-	K	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferase
NHKNCPHF_01173	2.48e-176	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHKNCPHF_01174	4.43e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHKNCPHF_01175	5.05e-146	XK27_05445	-	-	G	-	-	-	UDPglucose--hexose-1-phosphate uridylyltransferase
NHKNCPHF_01176	6.13e-283	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHKNCPHF_01177	4.81e-310	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NHKNCPHF_01178	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
NHKNCPHF_01179	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
NHKNCPHF_01180	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
NHKNCPHF_01181	2.04e-229	-	-	-	M	-	-	-	glycosyl transferase family 2
NHKNCPHF_01182	3.19e-166	-	-	-	S	-	-	-	Carbohydrate-binding domain-containing protein Cthe_2159
NHKNCPHF_01183	1.14e-183	-	-	-	P	-	-	-	molecular chaperone
NHKNCPHF_01184	1.38e-134	XK27_05505	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHKNCPHF_01185	1.5e-115	-	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
NHKNCPHF_01187	5.16e-66	hisE	3.5.4.19, 3.6.1.31, 5.3.1.16	-	E	ko:K01523,ko:K01814,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
NHKNCPHF_01188	3.36e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NHKNCPHF_01189	4.63e-175	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NHKNCPHF_01190	2.9e-167	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NHKNCPHF_01191	8.15e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NHKNCPHF_01192	2.36e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
NHKNCPHF_01193	4.35e-300	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NHKNCPHF_01194	2.93e-151	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NHKNCPHF_01195	3.26e-228	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NHKNCPHF_01196	6.24e-245	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NHKNCPHF_01197	1.75e-78	XK27_08085	-	-	-	-	-	-	-
NHKNCPHF_01198	6.23e-196	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
NHKNCPHF_01199	3.16e-179	hisJ	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
NHKNCPHF_01200	3.05e-152	-	-	-	S	-	-	-	tigr01906
NHKNCPHF_01201	1.74e-177	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHKNCPHF_01202	1.45e-180	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NHKNCPHF_01203	1.05e-273	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
NHKNCPHF_01206	3.86e-263	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NHKNCPHF_01207	3.91e-142	rmlC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NHKNCPHF_01208	7.83e-206	rfbA	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NHKNCPHF_01209	0.0	-	-	-	S	-	-	-	phospholipase Carboxylesterase
NHKNCPHF_01210	3.4e-255	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	oxidoreductase
NHKNCPHF_01211	3.62e-184	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
NHKNCPHF_01212	1.44e-183	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHKNCPHF_01213	3.25e-154	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NHKNCPHF_01214	5.03e-84	mesH	-	-	S	-	-	-	GtrA-like protein
NHKNCPHF_01215	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHKNCPHF_01216	4.31e-210	ybbR	-	-	S	-	-	-	Protein conserved in bacteria
NHKNCPHF_01217	7.91e-190	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHKNCPHF_01218	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain protein
NHKNCPHF_01219	2.07e-192	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
NHKNCPHF_01220	0.0	mprF	2.3.2.3	-	J	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHKNCPHF_01221	2.22e-171	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha beta hydrolase
NHKNCPHF_01222	7.55e-53	-	-	-	S	-	-	-	yiaA/B two helix domain
NHKNCPHF_01223	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	abc transporter atp-binding protein
NHKNCPHF_01224	5.27e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NHKNCPHF_01225	5.06e-240	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
NHKNCPHF_01226	4.92e-288	XK27_05680	-	-	M	-	-	-	carbamoylphosphate synthase large subunit
NHKNCPHF_01227	4.54e-197	XK27_05675	-	-	S	-	-	-	Esterase
NHKNCPHF_01228	1.07e-205	XK27_05670	-	-	S	ko:K07017	-	ko00000	Putative esterase
NHKNCPHF_01229	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NHKNCPHF_01230	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHKNCPHF_01231	2.72e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein Hpr
NHKNCPHF_01232	1.46e-282	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate dehydrogenase
NHKNCPHF_01233	4.07e-269	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
NHKNCPHF_01234	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NHKNCPHF_01235	9.66e-46	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NHKNCPHF_01236	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHKNCPHF_01237	4.51e-236	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHKNCPHF_01238	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHKNCPHF_01239	3.37e-192	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
NHKNCPHF_01240	2.09e-174	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
NHKNCPHF_01241	1.95e-41	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
NHKNCPHF_01242	2.24e-126	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	cell septum assembly
NHKNCPHF_01243	1.49e-154	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NHKNCPHF_01244	1.7e-299	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHKNCPHF_01245	5.77e-291	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHKNCPHF_01246	1.48e-185	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHKNCPHF_01247	3.68e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHKNCPHF_01248	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHKNCPHF_01249	5.19e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3165)
NHKNCPHF_01250	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NHKNCPHF_01251	6.57e-226	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NHKNCPHF_01252	2.18e-36	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
NHKNCPHF_01253	8.12e-103	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NHKNCPHF_01254	1.06e-116	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NHKNCPHF_01255	2.84e-134	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
NHKNCPHF_01256	3.32e-209	-	-	-	V	-	-	-	D-alanyl-D-alanine carboxypeptidase
NHKNCPHF_01257	1.59e-143	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
NHKNCPHF_01258	3.69e-234	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NHKNCPHF_01259	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NHKNCPHF_01260	2.67e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
NHKNCPHF_01261	9.64e-94	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
NHKNCPHF_01262	9.65e-163	sitB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K10830,ko:K11706,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NHKNCPHF_01263	3.37e-170	mtsC	-	-	P	ko:K11705,ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type Mn2 Zn2 transport systems, permease components
NHKNCPHF_01264	1.13e-219	psaA	-	-	P	ko:K11704,ko:K19971,ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NHKNCPHF_01265	1.29e-149	sirR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
NHKNCPHF_01266	5.96e-190	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NHKNCPHF_01267	8.87e-120	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NHKNCPHF_01268	0.0	-	-	-	M	-	-	-	Right handed beta helix region
NHKNCPHF_01269	2.62e-13	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
NHKNCPHF_01270	7.41e-190	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
NHKNCPHF_01271	2.65e-247	higA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	Pfam:DUF955
NHKNCPHF_01272	3.93e-67	-	-	-	-	-	-	-	-
NHKNCPHF_01273	3.22e-228	-	-	-	S	-	-	-	AAA domain
NHKNCPHF_01274	1.31e-181	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NHKNCPHF_01275	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
NHKNCPHF_01276	0.0	-	-	-	V	-	-	-	Type I restriction enzyme R protein N terminus (HSDR_N)
NHKNCPHF_01278	3.12e-172	sdh	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHKNCPHF_01279	2.35e-267	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
NHKNCPHF_01280	2.07e-147	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHKNCPHF_01281	6.65e-198	hmpP2	-	-	G	-	-	-	hydrolase
NHKNCPHF_01282	3.25e-35	-	-	-	P	-	-	-	Hemerythrin HHE cation binding domain protein
NHKNCPHF_01283	4.74e-192	-	3.5.1.28	-	M	ko:K01447,ko:K07273	-	ko00000,ko01000	Glycosyl hydrolase, family 25
NHKNCPHF_01284	2.49e-105	-	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHKNCPHF_01285	4.87e-148	pgm	-	-	G	-	-	-	Phosphoglycerate mutase
NHKNCPHF_01287	2.2e-222	-	-	-	S	ko:K07025	-	ko00000	hydrolase
NHKNCPHF_01288	1.73e-36	-	-	-	-	-	-	-	-
NHKNCPHF_01289	1.44e-209	-	-	-	M	-	-	-	LysM domain
NHKNCPHF_01290	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NHKNCPHF_01292	2.54e-19	-	-	-	-	-	-	-	-
NHKNCPHF_01293	1.55e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NHKNCPHF_01294	2.97e-45	XK27_12190	-	-	S	-	-	-	protein conserved in bacteria
NHKNCPHF_01296	6.28e-112	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin synthase
NHKNCPHF_01297	0.0	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
NHKNCPHF_01298	7.14e-228	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
NHKNCPHF_01300	6.48e-89	ytxH	-	-	S	-	-	-	General stress protein
NHKNCPHF_01301	9.98e-28	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NHKNCPHF_01302	2.14e-190	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHKNCPHF_01303	1.12e-215	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHKNCPHF_01304	1.02e-55	WQ51_05770	-	-	KT	-	-	-	PspC domain
NHKNCPHF_01305	1.17e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NHKNCPHF_01306	0.0	tex	-	-	K	ko:K06959	-	ko00000	Transcriptional accessory protein
NHKNCPHF_01308	1.14e-199	XK27_03015	-	-	S	ko:K07089	-	ko00000	permease
NHKNCPHF_01309	4.15e-192	XK27_03010	-	-	S	ko:K08986	-	ko00000	TIGR03943 family
NHKNCPHF_01310	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	Sulfate permease and related transporters (MFS superfamily)
NHKNCPHF_01311	4.47e-131	-	-	-	-	-	-	-	-
NHKNCPHF_01312	1.4e-152	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NHKNCPHF_01313	5.54e-120	-	-	-	S	-	-	-	CAAX protease self-immunity
NHKNCPHF_01314	6.44e-69	-	-	-	-	-	-	-	-
NHKNCPHF_01316	1.18e-83	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
NHKNCPHF_01317	3.25e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
NHKNCPHF_01320	2.72e-111	isplu5A	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
NHKNCPHF_01321	5.28e-159	-	-	-	V	-	-	-	CAAX protease self-immunity
NHKNCPHF_01322	1.55e-62	-	-	-	-	-	-	-	-
NHKNCPHF_01323	4.58e-98	-	-	-	K	-	-	-	TetR family transcriptional regulator
NHKNCPHF_01324	6.21e-109	-	-	-	Q	-	-	-	Methyltransferase domain
NHKNCPHF_01325	1.88e-179	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHKNCPHF_01326	3.73e-222	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	dehydrogenase E1 component
NHKNCPHF_01327	5.03e-211	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	Acetoin dehydrogenase E1 component subunit alpha
NHKNCPHF_01328	2.66e-216	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NHKNCPHF_01329	3.71e-31	-	-	-	S	-	-	-	CsbD-like
NHKNCPHF_01330	1.55e-42	ytgB	-	-	S	-	-	-	Membrane
NHKNCPHF_01331	2.47e-219	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
NHKNCPHF_01332	2.41e-202	yegS	-	-	I	-	-	-	Diacylglycerol kinase
NHKNCPHF_01333	8.71e-159	-	-	-	S	-	-	-	Putative esterase
NHKNCPHF_01334	7.1e-229	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NHKNCPHF_01335	7.95e-171	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NHKNCPHF_01336	1.05e-219	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHKNCPHF_01337	9.48e-160	-	-	-	V	-	-	-	CAAX protease self-immunity
NHKNCPHF_01338	2.4e-195	-	-	-	S	-	-	-	Domain of unknown function (DUF4300)
NHKNCPHF_01339	3.02e-124	tetR	-	-	K	-	-	-	transcriptional regulator
NHKNCPHF_01340	0.0	-	-	-	P	-	-	-	Major facilitator superfamily
NHKNCPHF_01341	1.76e-18	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
NHKNCPHF_01343	4.65e-141	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
NHKNCPHF_01344	3.59e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family
NHKNCPHF_01345	2.54e-123	yagB	-	-	F	ko:K06950	-	ko00000	HD superfamily hydrolase
NHKNCPHF_01346	5.71e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHKNCPHF_01347	1.01e-192	ChZ00x2	-	-	S	-	-	-	EDD domain protein, DegV family
NHKNCPHF_01348	2.3e-258	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	transporter
NHKNCPHF_01349	2.78e-168	-	-	-	S	-	-	-	Domain of unknown function (DUF4336)
NHKNCPHF_01350	2.56e-175	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHKNCPHF_01352	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
NHKNCPHF_01353	4.62e-81	-	-	-	K	ko:K21903	-	ko00000,ko03000	Transcriptional regulator
NHKNCPHF_01354	3.59e-69	XK27_05385	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
NHKNCPHF_01355	1.39e-101	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
NHKNCPHF_01356	2.12e-13	-	-	-	S	-	-	-	UPF0489 domain
NHKNCPHF_01359	0.0	yheS_2	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPase components of ABC transporters with duplicated ATPase domains
NHKNCPHF_01360	9.86e-265	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Major facilitator Superfamily
NHKNCPHF_01361	1.47e-35	-	-	-	K	-	-	-	WYL domain
NHKNCPHF_01362	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHKNCPHF_01363	1.28e-126	mip	-	-	S	-	-	-	hydroperoxide reductase activity
NHKNCPHF_01364	4.11e-252	-	-	-	I	-	-	-	acyl-CoA dehydrogenase
NHKNCPHF_01365	1.77e-193	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	C4-dicarboxylate transporter malic acid transport
NHKNCPHF_01366	0.0	msrR	-	-	K	-	-	-	Transcriptional regulator
NHKNCPHF_01367	2.42e-197	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
NHKNCPHF_01368	1.87e-112	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NHKNCPHF_01369	1.77e-299	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NHKNCPHF_01370	2.93e-210	hicD2	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NHKNCPHF_01371	1.22e-70	XK26_04240	-	-	S	-	-	-	Belongs to the UPF0342 family
NHKNCPHF_01372	5.29e-262	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
NHKNCPHF_01373	1.83e-279	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NHKNCPHF_01374	2.05e-257	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NHKNCPHF_01375	1.39e-197	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NHKNCPHF_01376	1.37e-149	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NHKNCPHF_01377	1.19e-279	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
NHKNCPHF_01378	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
NHKNCPHF_01379	1.1e-34	WQ51_00785	-	-	-	-	-	-	-
NHKNCPHF_01380	6.13e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHKNCPHF_01381	2.08e-101	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NHKNCPHF_01382	2.91e-256	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NHKNCPHF_01383	3.41e-256	XK27_07735	-	-	S	-	-	-	YjbR
NHKNCPHF_01384	9.07e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	Catabolite control protein A
NHKNCPHF_01385	3.62e-247	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
NHKNCPHF_01386	3.35e-84	yugI	-	-	J	ko:K07570	-	ko00000	RNA binding protein, contains ribosomal protein S1 domain
NHKNCPHF_01387	0.0	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHKNCPHF_01388	1.98e-105	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NHKNCPHF_01389	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHKNCPHF_01390	1.06e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
NHKNCPHF_01391	5.68e-279	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	Major Facilitator
NHKNCPHF_01392	1.35e-133	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHKNCPHF_01393	5.27e-196	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHKNCPHF_01394	3.34e-212	era	-	-	M	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHKNCPHF_01395	2.97e-86	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NHKNCPHF_01396	1.31e-113	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHKNCPHF_01397	2.05e-194	licT	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
NHKNCPHF_01398	2.63e-136	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHKNCPHF_01399	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
NHKNCPHF_01400	1.42e-182	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHKNCPHF_01401	3.16e-198	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHKNCPHF_01402	7.21e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NHKNCPHF_01403	2.42e-12	-	-	-	-	-	-	-	-
NHKNCPHF_01404	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NHKNCPHF_01405	6.08e-102	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain protein
NHKNCPHF_01406	1.05e-167	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHKNCPHF_01407	2.2e-151	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHKNCPHF_01408	3.31e-47	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
NHKNCPHF_01409	6.14e-233	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHKNCPHF_01410	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NHKNCPHF_01411	5.5e-111	XK27_09440	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
NHKNCPHF_01412	2.23e-65	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
NHKNCPHF_01413	2.99e-221	-	-	-	S	-	-	-	oxidoreductase
NHKNCPHF_01414	2.37e-289	murN	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	FemAB family
NHKNCPHF_01415	2.28e-149	-	-	-	M	-	-	-	Pfam SNARE associated Golgi protein
NHKNCPHF_01416	1.19e-136	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
NHKNCPHF_01419	9.51e-268	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein S1
NHKNCPHF_01422	4.89e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
NHKNCPHF_01423	7.12e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NHKNCPHF_01424	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHKNCPHF_01425	2e-145	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	adenylyltransferase
NHKNCPHF_01428	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHKNCPHF_01429	2.21e-140	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHKNCPHF_01430	4.35e-19	-	-	-	L	-	-	-	Helix-hairpin-helix DNA-binding motif class 1
NHKNCPHF_01431	3.14e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF1912)
NHKNCPHF_01432	3.63e-220	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	Homocysteine
NHKNCPHF_01433	0.0	lysP	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NHKNCPHF_01434	9.58e-144	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NHKNCPHF_01435	1.79e-287	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHKNCPHF_01436	2.97e-30	-	-	-	-	-	-	-	-
NHKNCPHF_01437	5.77e-118	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHKNCPHF_01438	3.63e-214	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHKNCPHF_01439	3.12e-271	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	synthase
NHKNCPHF_01440	4.07e-287	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
NHKNCPHF_01441	1.08e-102	-	-	-	K	-	-	-	hmm pf08876
NHKNCPHF_01442	3.52e-152	hly-III	-	-	K	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
NHKNCPHF_01443	1.64e-39	pspC	-	-	KT	-	-	-	PspC domain protein
NHKNCPHF_01444	6.35e-255	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
NHKNCPHF_01445	1.82e-201	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHKNCPHF_01446	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHKNCPHF_01448	0.0	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NHKNCPHF_01449	1.21e-242	dgs	2.4.1.208	GT4	M	ko:K13677	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NHKNCPHF_01450	0.0	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
NHKNCPHF_01451	7.33e-152	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHKNCPHF_01452	4.4e-43	-	-	-	-	-	-	-	-
NHKNCPHF_01453	8.64e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	AdP-ribose pyrophosphatase
NHKNCPHF_01454	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHKNCPHF_01455	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
NHKNCPHF_01456	1.7e-234	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NHKNCPHF_01457	1.02e-213	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
NHKNCPHF_01458	1.72e-217	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
NHKNCPHF_01459	2.35e-188	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
NHKNCPHF_01460	2.09e-315	merA	-	-	C	-	-	-	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHKNCPHF_01461	2.81e-164	-	-	-	E	-	-	-	alpha/beta hydrolase fold
NHKNCPHF_01463	1.67e-250	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
NHKNCPHF_01464	1.61e-274	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NHKNCPHF_01465	1.7e-138	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NHKNCPHF_01466	5.36e-148	-	-	-	S	-	-	-	VIT family
NHKNCPHF_01467	2.22e-184	-	-	-	F	-	-	-	Phosphorylase superfamily
NHKNCPHF_01469	1.61e-40	XK27_00085	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
NHKNCPHF_01470	9.64e-251	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
NHKNCPHF_01471	4.26e-157	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHKNCPHF_01472	7.97e-251	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NHKNCPHF_01473	0.0	lmrA	-	-	V	ko:K06147,ko:K18888	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_01474	0.0	msbA_1	-	-	V	ko:K18887	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_01475	2.84e-240	-	-	-	L	-	-	-	DNA integration
NHKNCPHF_01477	2.41e-188	-	-	-	-	-	-	-	-
NHKNCPHF_01482	5.52e-65	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHKNCPHF_01483	8.41e-102	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHKNCPHF_01484	2.18e-269	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	permease protein
NHKNCPHF_01485	5.6e-158	salX	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHKNCPHF_01486	1.4e-245	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHKNCPHF_01487	1.21e-165	-	-	-	S	-	-	-	Putative SAM-dependent methyltransferase
NHKNCPHF_01488	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase ammonia chain
NHKNCPHF_01489	1.86e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase glutamine chain
NHKNCPHF_01490	5.83e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NHKNCPHF_01491	4.94e-282	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	uracil Permease
NHKNCPHF_01492	1.45e-114	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHKNCPHF_01493	1.03e-207	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NHKNCPHF_01494	2.82e-100	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHKNCPHF_01495	6.02e-216	lysR	-	-	K	-	-	-	transcriptional regulator (lysR family)
NHKNCPHF_01497	1.03e-21	-	-	-	-	-	-	-	-
NHKNCPHF_01498	1.72e-86	-	-	-	K	-	-	-	Helix-turn-helix
NHKNCPHF_01502	3.03e-180	ppiA	5.2.1.8	-	O	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHKNCPHF_01503	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHKNCPHF_01505	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	permease
NHKNCPHF_01506	1.17e-51	ynzC	-	-	S	-	-	-	UPF0291 protein
NHKNCPHF_01507	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NHKNCPHF_01508	1.23e-226	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NHKNCPHF_01509	3.9e-285	-	-	-	S	-	-	-	membrane
NHKNCPHF_01510	2.48e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NHKNCPHF_01511	0.0	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
NHKNCPHF_01512	6.26e-161	-	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
NHKNCPHF_01513	1.12e-104	-	-	-	S	-	-	-	Bacterial inner membrane protein
NHKNCPHF_01514	4.95e-186	XK27_04800	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NHKNCPHF_01515	3.77e-139	mur1	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
NHKNCPHF_01516	1.86e-70	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
NHKNCPHF_01517	2.03e-290	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter
NHKNCPHF_01518	4.5e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHKNCPHF_01519	2e-73	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NHKNCPHF_01520	2.51e-171	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
NHKNCPHF_01521	1.3e-205	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	dna polymerase iii
NHKNCPHF_01522	5.67e-141	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHKNCPHF_01524	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NHKNCPHF_01525	3.13e-173	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHKNCPHF_01526	6.46e-285	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHKNCPHF_01527	1.44e-277	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NHKNCPHF_01528	1.24e-89	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NHKNCPHF_01529	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHKNCPHF_01530	9.08e-202	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHKNCPHF_01531	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHKNCPHF_01532	4.99e-113	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHKNCPHF_01533	2.96e-85	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NHKNCPHF_01534	1.66e-155	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NHKNCPHF_01535	5.88e-23	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHKNCPHF_01536	0.0	-	-	-	-	-	-	-	-
NHKNCPHF_01537	4.84e-277	nlaXM	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	cytosine-specific methyltransferase
NHKNCPHF_01538	5.62e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
NHKNCPHF_01540	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHKNCPHF_01542	1.58e-24	-	-	-	-	-	-	-	-
NHKNCPHF_01543	1.96e-125	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHKNCPHF_01544	5.57e-135	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHKNCPHF_01545	1.38e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NHKNCPHF_01547	3.89e-188	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	Transporter
NHKNCPHF_01548	3.54e-196	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NHKNCPHF_01549	8.5e-303	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NHKNCPHF_01550	5.16e-192	icaB	-	-	G	-	-	-	deacetylase
NHKNCPHF_01551	5.23e-257	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
NHKNCPHF_01552	1.04e-163	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
NHKNCPHF_01553	3.86e-281	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHKNCPHF_01554	8.08e-236	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NHKNCPHF_01555	1.75e-172	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
NHKNCPHF_01556	6.42e-94	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
NHKNCPHF_01557	1.68e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NHKNCPHF_01558	0.0	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
NHKNCPHF_01559	3.8e-17	-	-	-	-	-	-	-	-
NHKNCPHF_01560	5.38e-291	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NHKNCPHF_01561	8.02e-172	agrA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
NHKNCPHF_01562	0.0	-	-	-	M	-	-	-	GBS Bsp-like repeat
NHKNCPHF_01563	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHKNCPHF_01564	3.65e-109	XK27_03390	-	-	S	-	-	-	LURP-one-related
NHKNCPHF_01565	1.78e-234	prsA	3.1.3.16, 5.2.1.8	-	O	ko:K01802,ko:K03769,ko:K07533,ko:K20074	-	ko00000,ko01000,ko01009,ko03110	peptidyl-prolyl cis-trans isomerase activity
NHKNCPHF_01566	2.41e-154	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-Methyltransferase
NHKNCPHF_01567	1.44e-276	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NHKNCPHF_01568	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
NHKNCPHF_01569	1.23e-208	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NHKNCPHF_01570	0.0	-	-	-	S	-	-	-	Glucan-binding protein C
NHKNCPHF_01571	4.67e-140	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
NHKNCPHF_01572	3.03e-215	-	-	-	K	-	-	-	transcriptional regulator (lysR family)
NHKNCPHF_01573	9.51e-203	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
NHKNCPHF_01574	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHKNCPHF_01578	6.93e-239	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
NHKNCPHF_01579	2.65e-205	sip	-	-	M	-	-	-	LysM domain protein
NHKNCPHF_01580	2.72e-46	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NHKNCPHF_01581	1.65e-205	yitL	-	-	S	ko:K00243	-	ko00000	Protein conserved in bacteria
NHKNCPHF_01582	7.89e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHKNCPHF_01583	2.78e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NHKNCPHF_01584	1.34e-277	sptS	-	-	T	-	-	-	Histidine kinase
NHKNCPHF_01585	8.64e-153	dltr	-	-	T	-	-	-	response regulator
NHKNCPHF_01586	2.07e-142	-	2.7.6.5	-	S	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
NHKNCPHF_01587	3.17e-144	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NHKNCPHF_01588	0.0	lmrA2	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
NHKNCPHF_01589	0.0	lmrA1	-	-	V	ko:K02021,ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
NHKNCPHF_01590	2.64e-93	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NHKNCPHF_01591	2.73e-92	def_1	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NHKNCPHF_01592	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHKNCPHF_01593	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NHKNCPHF_01594	1.26e-269	nadR	-	-	H	-	-	-	adenylyltransferase
NHKNCPHF_01595	4.05e-165	-	-	-	F	-	-	-	AdP-ribose pyrophosphatase
NHKNCPHF_01596	1.56e-30	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NHKNCPHF_01597	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	abc transporter atp-binding protein
NHKNCPHF_01598	5.22e-276	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHKNCPHF_01599	2.21e-179	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHKNCPHF_01600	1.88e-188	-	-	-	S	-	-	-	EDD domain protein, DegV family
NHKNCPHF_01601	2.63e-82	WQ51_03320	-	-	S	-	-	-	cog cog4835
NHKNCPHF_01602	1.99e-170	ydaF_2	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NHKNCPHF_01603	1.55e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NHKNCPHF_01604	1.99e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NHKNCPHF_01605	9.37e-118	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
NHKNCPHF_01606	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NHKNCPHF_01607	0.0	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NHKNCPHF_01608	1.85e-284	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHKNCPHF_01609	3.2e-265	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NHKNCPHF_01610	5.41e-06	-	-	-	-	-	-	-	-
NHKNCPHF_01611	1.04e-289	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NHKNCPHF_01612	0.0	gor	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHKNCPHF_01613	0.0	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHKNCPHF_01614	1.12e-212	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NHKNCPHF_01615	9.22e-164	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
NHKNCPHF_01616	2.22e-290	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NHKNCPHF_01617	6.58e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHKNCPHF_01618	4.63e-177	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NHKNCPHF_01619	6.95e-204	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHKNCPHF_01620	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NHKNCPHF_01621	1.19e-93	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHKNCPHF_01622	1e-82	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHKNCPHF_01623	3.03e-296	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHKNCPHF_01624	5.57e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NHKNCPHF_01625	4.33e-207	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
NHKNCPHF_01626	1.08e-219	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	2-Nitropropane dioxygenase
NHKNCPHF_01627	2.12e-40	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHKNCPHF_01628	8.56e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHKNCPHF_01629	2.67e-96	XK27_02735	-	-	K	-	-	-	Transcriptional regulator, MarR family
NHKNCPHF_01630	2.27e-179	phaB	5.3.3.14, 5.3.3.18	-	I	ko:K15866,ko:K18474	ko00061,ko00360,ko01120,map00061,map00360,map01120	ko00000,ko00001,ko01000,ko01004	Belongs to the enoyl-CoA hydratase isomerase family
NHKNCPHF_01631	1.4e-147	yhfA	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
NHKNCPHF_01632	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NHKNCPHF_01633	4.39e-244	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
NHKNCPHF_01634	5.34e-314	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHKNCPHF_01635	1.27e-175	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
NHKNCPHF_01636	1.99e-132	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
NHKNCPHF_01637	4.12e-137	-	-	-	S	-	-	-	Domain of unknown function (DUF1803)
NHKNCPHF_01638	1.92e-212	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
NHKNCPHF_01646	4.11e-123	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHKNCPHF_01647	6.69e-111	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
NHKNCPHF_01648	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NHKNCPHF_01649	2.14e-140	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
NHKNCPHF_01650	3.47e-214	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NHKNCPHF_01651	2.2e-143	XK27_04065	-	-	S	ko:K04767	-	ko00000	CBS domain
NHKNCPHF_01652	4.6e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NHKNCPHF_01653	9.34e-176	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NHKNCPHF_01654	6.66e-184	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHKNCPHF_01655	9.55e-189	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHKNCPHF_01656	3.57e-270	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NHKNCPHF_01657	5.93e-60	ylbG	-	-	S	-	-	-	UPF0298 protein
NHKNCPHF_01658	2.63e-94	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
NHKNCPHF_01659	3.75e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHKNCPHF_01660	1.06e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHKNCPHF_01661	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	G	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Belongs to the glycosyl hydrolase 68 family
NHKNCPHF_01662	0.0	-	3.2.1.26, 3.2.1.65	GH32	G	ko:K01193,ko:K01212	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NHKNCPHF_01663	5.51e-285	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NHKNCPHF_01664	3.41e-256	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NHKNCPHF_01665	0.0	pacL	-	-	P	-	-	-	cation transport ATPase
NHKNCPHF_01666	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
NHKNCPHF_01667	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHKNCPHF_01668	2.77e-128	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NHKNCPHF_01669	5.68e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHKNCPHF_01670	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHKNCPHF_01671	2.19e-56	ylxQ	-	-	J	-	-	-	ribosomal protein
NHKNCPHF_01672	9.2e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Nucleic-acid-binding protein implicated in transcription termination
NHKNCPHF_01673	1.37e-258	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NHKNCPHF_01674	1.75e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NHKNCPHF_01675	1.04e-247	brpA	-	-	K	-	-	-	Transcriptional
NHKNCPHF_01676	1.06e-116	XK27_05885	2.3.1.82	-	M	ko:K18816	-	br01600,ko00000,ko01000,ko01504	phosphinothricin N-acetyltransferase activity
NHKNCPHF_01677	1.79e-100	ydiB	-	-	M	ko:K06925	-	ko00000,ko03016	ATPase or kinase
NHKNCPHF_01678	7.03e-316	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NHKNCPHF_01679	5.08e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
NHKNCPHF_01680	9.8e-177	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Metal-dependent hydrolase
NHKNCPHF_01681	9.97e-223	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHKNCPHF_01682	1.25e-170	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
NHKNCPHF_01683	1.97e-202	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
NHKNCPHF_01684	1.34e-86	manO	-	-	S	-	-	-	Protein conserved in bacteria
NHKNCPHF_01685	1.39e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHKNCPHF_01686	2.04e-167	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
NHKNCPHF_01687	1.22e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
NHKNCPHF_01688	7.55e-82	manO	-	-	S	-	-	-	protein conserved in bacteria
NHKNCPHF_01689	1.96e-297	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHKNCPHF_01690	4.86e-142	-	-	-	-	-	-	-	-
NHKNCPHF_01691	5.05e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NHKNCPHF_01692	2.54e-212	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NHKNCPHF_01693	2.48e-274	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
NHKNCPHF_01694	3.52e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHKNCPHF_01695	0.0	covS	-	-	T	-	-	-	Histidine kinase
NHKNCPHF_01696	1.62e-159	csrR	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHKNCPHF_01697	2.3e-118	ylbN	-	-	K	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
NHKNCPHF_01698	2.79e-164	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Ribosomal RNA small subunit methyltransferase G
NHKNCPHF_01699	6.17e-295	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	COG0168 Trk-type K transport systems, membrane components
NHKNCPHF_01700	5.44e-155	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
NHKNCPHF_01701	3.54e-191	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
NHKNCPHF_01702	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHKNCPHF_01703	5.2e-121	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
NHKNCPHF_01704	1.15e-199	ilvH	-	-	S	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
NHKNCPHF_01705	5.12e-268	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NHKNCPHF_01706	1.04e-151	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_01707	2.08e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHKNCPHF_01708	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NHKNCPHF_01709	1.03e-211	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
NHKNCPHF_01710	2.35e-183	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NHKNCPHF_01711	8.74e-300	-	-	-	S	-	-	-	Domain of unknown function (DUF4173)
NHKNCPHF_01712	1.09e-72	yhaI	-	-	L	-	-	-	Membrane
NHKNCPHF_01713	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHKNCPHF_01714	5.83e-197	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
NHKNCPHF_01715	5.04e-127	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Membrane-associated phospholipid phosphatase
NHKNCPHF_01716	3.75e-116	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHKNCPHF_01717	1.31e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHKNCPHF_01718	9.42e-313	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	Potassium transporter peripheral membrane component
NHKNCPHF_01719	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
NHKNCPHF_01720	9.94e-20	yidD	-	-	M	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
NHKNCPHF_01721	1.23e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NHKNCPHF_01722	1.99e-124	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHKNCPHF_01723	8.23e-157	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHKNCPHF_01724	1.55e-170	xerD	-	-	L	-	-	-	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NHKNCPHF_01725	1.81e-113	ykuL	-	-	S	-	-	-	CBS domain
NHKNCPHF_01726	1.3e-126	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NHKNCPHF_01727	2.05e-230	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHKNCPHF_01728	8.38e-192	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NHKNCPHF_01729	2.31e-48	-	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
NHKNCPHF_01730	8.96e-117	-	-	-	K	-	-	-	transcriptional regulator
NHKNCPHF_01731	4.07e-310	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHKNCPHF_01733	2.33e-143	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NHKNCPHF_01734	3.62e-121	XK27_09705	-	-	S	ko:K06950	-	ko00000	HD superfamily hydrolase
NHKNCPHF_01735	1.54e-165	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHKNCPHF_01736	4.71e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NHKNCPHF_01737	9.19e-213	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHKNCPHF_01738	1.17e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHKNCPHF_01739	0.0	mltG	-	-	ADL	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NHKNCPHF_01740	1.42e-112	-	-	-	K	-	-	-	histone acetyltransferase HPA2 and related acetyltransferases
NHKNCPHF_01741	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NHKNCPHF_01742	3.79e-25	XK27_11680	-	-	-	-	-	-	-
NHKNCPHF_01743	0.0	snf	-	-	L	-	-	-	Superfamily II DNA RNA helicases, SNF2 family'
NHKNCPHF_01744	0.0	mapZ	-	-	D	ko:K20073	-	ko00000	Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NHKNCPHF_01745	1.45e-281	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NHKNCPHF_01746	1.14e-65	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHKNCPHF_01747	1.2e-121	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NHKNCPHF_01748	4.93e-141	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHKNCPHF_01749	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NHKNCPHF_01750	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
NHKNCPHF_01751	3.35e-96	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
NHKNCPHF_01752	8.04e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NHKNCPHF_01753	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHKNCPHF_01754	1.95e-271	-	-	-	V	-	-	-	FtsX-like permease family
NHKNCPHF_01755	1.82e-155	-	-	-	V	-	-	-	abc transporter atp-binding protein
NHKNCPHF_01756	9.28e-158	mta	-	-	K	ko:K21743	-	ko00000,ko03000	Transcriptional
NHKNCPHF_01757	9.54e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NHKNCPHF_01758	2.33e-98	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
NHKNCPHF_01759	4.94e-168	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
NHKNCPHF_01760	9.73e-195	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_01761	4.96e-71	-	-	-	K	-	-	-	regulation of RNA biosynthetic process
NHKNCPHF_01762	2.07e-60	-	3.2.2.21	-	S	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	YCII-related domain
NHKNCPHF_01763	2.13e-60	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
NHKNCPHF_01764	1.5e-296	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
NHKNCPHF_01765	9.49e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NHKNCPHF_01766	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NHKNCPHF_01767	3.23e-172	-	-	-	K	ko:K22103	-	ko00000,ko03000	transcriptional regulator (DeoR family)
NHKNCPHF_01768	1.05e-184	cof	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NHKNCPHF_01769	1.64e-94	-	3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27	-	I	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
NHKNCPHF_01770	2.8e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NHKNCPHF_01771	1.05e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Belongs to the SecE SEC61-gamma family
NHKNCPHF_01772	2.73e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NHKNCPHF_01773	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NHKNCPHF_01774	7.29e-211	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NHKNCPHF_01775	2.21e-72	WQ51_06355	-	-	S	-	-	-	TM2 domain
NHKNCPHF_01776	2.43e-59	-	-	-	-	-	-	-	-
NHKNCPHF_01778	1.5e-115	-	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
NHKNCPHF_01779	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHKNCPHF_01780	7.72e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHKNCPHF_01781	6.07e-183	cmpC	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHKNCPHF_01782	0.0	XK27_00665	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
NHKNCPHF_01783	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHKNCPHF_01784	6.62e-296	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NHKNCPHF_01785	2.49e-185	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NHKNCPHF_01786	3.56e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHKNCPHF_01787	3.49e-61	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
NHKNCPHF_01788	2.37e-161	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
NHKNCPHF_01789	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
NHKNCPHF_01790	8.7e-199	Z012_04635	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
NHKNCPHF_01791	2.42e-281	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHKNCPHF_01792	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHKNCPHF_01793	6.62e-138	-	-	-	L	-	-	-	Transposase IS116 IS110 IS902
NHKNCPHF_01794	2.58e-77	B4168_4126	-	-	L	ko:K07493	-	ko00000	MULE transposase domain
NHKNCPHF_01795	7.78e-21	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
NHKNCPHF_01796	2.58e-77	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	sorbitol-specific, IIA component
NHKNCPHF_01797	4.63e-228	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS sorbitol transporter subunit IIB
NHKNCPHF_01798	6.32e-124	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system glucitol sorbitol-specific
NHKNCPHF_01799	2.45e-109	gutM	-	-	K	ko:K02466	-	ko00000	phosphoenolpyruvate-dependent sugar phosphotransferase system
NHKNCPHF_01800	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
NHKNCPHF_01801	4.62e-182	sorD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHKNCPHF_01802	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NHKNCPHF_01803	1.79e-196	rgfB	3.1.3.90	-	L	ko:K06896	ko00500,map00500	ko00000,ko00001,ko01000	Endonuclease/Exonuclease/phosphatase family
NHKNCPHF_01804	0.0	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHKNCPHF_01805	3.69e-203	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
NHKNCPHF_01806	4.25e-164	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHKNCPHF_01807	3.43e-173	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NHKNCPHF_01808	8.68e-93	adcR	-	-	K	-	-	-	transcriptional
NHKNCPHF_01809	2.41e-233	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHKNCPHF_01810	7.78e-201	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHKNCPHF_01811	3.52e-34	-	-	-	-	-	-	-	-
NHKNCPHF_01812	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
NHKNCPHF_01813	4.28e-97	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NHKNCPHF_01814	1.29e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHKNCPHF_01815	4e-297	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
NHKNCPHF_01816	1.65e-176	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NHKNCPHF_01817	4.45e-242	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
NHKNCPHF_01818	7.31e-166	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NHKNCPHF_01820	1.75e-195	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NHKNCPHF_01821	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NHKNCPHF_01822	4.26e-168	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHKNCPHF_01823	6.14e-61	-	-	-	-	-	-	-	-
NHKNCPHF_01824	1.01e-165	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NHKNCPHF_01827	2.66e-66	-	-	-	-	-	-	-	-
NHKNCPHF_01828	8.72e-188	agrC	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NHKNCPHF_01829	6.47e-156	agrA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	response regulator
NHKNCPHF_01832	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
NHKNCPHF_01833	2.61e-126	-	-	-	V	-	-	-	VanZ like family
NHKNCPHF_01834	3.52e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHKNCPHF_01835	5.88e-242	XK27_00055	-	-	P	-	-	-	Major Facilitator
NHKNCPHF_01836	1.1e-144	-	-	-	K	-	-	-	Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NHKNCPHF_01837	5.97e-145	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHKNCPHF_01838	7.82e-302	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NHKNCPHF_01839	0.0	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
NHKNCPHF_01840	9.59e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHKNCPHF_01841	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHKNCPHF_01842	4.09e-107	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NHKNCPHF_01843	0.0	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NHKNCPHF_01844	1.13e-168	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHKNCPHF_01845	2.12e-224	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
NHKNCPHF_01846	1.5e-96	-	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NHKNCPHF_01847	5.04e-109	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
NHKNCPHF_01848	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHKNCPHF_01849	1.24e-101	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NHKNCPHF_01850	1.81e-292	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHKNCPHF_01851	1.67e-178	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
NHKNCPHF_01852	1.31e-113	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
NHKNCPHF_01855	1.23e-105	hmpT	-	-	S	-	-	-	cog cog4720
NHKNCPHF_01856	7.1e-175	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	phosphomethylpyrimidine kinase
NHKNCPHF_01857	2.14e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHKNCPHF_01858	6.04e-252	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHKNCPHF_01859	3.12e-134	thiJ-2	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NHKNCPHF_01860	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NHKNCPHF_01861	6.99e-105	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHKNCPHF_01862	6.66e-237	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHKNCPHF_01863	4.75e-132	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Muramidase (Flagellum-specific)
NHKNCPHF_01864	1.13e-177	yodJ	3.4.16.4, 3.4.17.14	-	M	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
NHKNCPHF_01865	3.28e-166	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase
NHKNCPHF_01866	5.19e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NHKNCPHF_01867	3.56e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	UPF0237 protein
NHKNCPHF_01868	6.05e-295	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
NHKNCPHF_01869	6.12e-193	srtB	-	-	S	-	-	-	Sortase family
NHKNCPHF_01871	3.02e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
NHKNCPHF_01873	1.7e-79	-	-	-	O	-	-	-	Protein conserved in bacteria
NHKNCPHF_01875	2.25e-65	yegS	-	-	I	-	-	-	Diacylglycerol kinase
NHKNCPHF_01876	2.09e-89	-	-	-	S	-	-	-	membrane protein of uknown function UCP014873
NHKNCPHF_01877	1.05e-44	int	-	-	L	-	-	-	DNA integration
NHKNCPHF_01878	2.12e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NHKNCPHF_01879	7.02e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHKNCPHF_01880	1.21e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
NHKNCPHF_01882	4.13e-195	yitS	-	-	S	-	-	-	DegV family
NHKNCPHF_01883	5.73e-120	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
NHKNCPHF_01884	1.44e-171	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHKNCPHF_01886	1.22e-89	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NHKNCPHF_01887	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NHKNCPHF_01889	6.37e-144	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
NHKNCPHF_01890	8e-178	-	-	-	S	-	-	-	SseB protein N-terminal domain
NHKNCPHF_01891	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NHKNCPHF_01892	2e-287	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NHKNCPHF_01893	4.19e-290	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NHKNCPHF_01894	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
NHKNCPHF_01895	5.72e-99	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NHKNCPHF_01896	3.41e-107	-	-	-	S	-	-	-	Putative small multi-drug export protein
NHKNCPHF_01897	1.23e-233	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHKNCPHF_01898	2.48e-176	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NHKNCPHF_01899	4.96e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	alkyl hydroperoxide reductase
NHKNCPHF_01900	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	alkyl hydroperoxide reductase
NHKNCPHF_01902	2.58e-121	XK27_03570	-	-	S	ko:K19784	-	ko00000	reductase
NHKNCPHF_01903	1.89e-95	-	-	-	K	-	-	-	Transcriptional regulator, marr family
NHKNCPHF_01904	1.4e-48	XK27_02060	-	-	S	-	-	-	Transglycosylase associated protein
NHKNCPHF_01905	2.94e-300	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
NHKNCPHF_01906	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHKNCPHF_01907	8.58e-94	nudC	3.6.1.13, 3.6.1.22	-	L	ko:K01515,ko:K03426	ko00230,ko00760,ko01100,ko04146,map00230,map00760,map01100,map04146	ko00000,ko00001,ko01000	NAD+ diphosphatase activity
NHKNCPHF_01908	1.63e-64	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
NHKNCPHF_01909	2.64e-98	ansR	-	-	K	-	-	-	Transcriptional
NHKNCPHF_01910	5.19e-98	-	-	-	-	-	-	-	-
NHKNCPHF_01911	1.04e-290	-	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
NHKNCPHF_01912	1.39e-88	-	-	-	-	-	-	-	-
NHKNCPHF_01913	1.45e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
NHKNCPHF_01914	1.72e-267	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NHKNCPHF_01928	8.92e-87	spxA_2	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
NHKNCPHF_01929	5.07e-261	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHKNCPHF_01930	1.81e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NHKNCPHF_01931	1.5e-135	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	3-methyladenine DNA glycosylase
NHKNCPHF_01932	1.03e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHKNCPHF_01934	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHKNCPHF_01936	3.78e-92	-	-	-	K	-	-	-	LytTr DNA-binding domain
NHKNCPHF_01937	1.07e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NHKNCPHF_01938	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHKNCPHF_01939	6.33e-74	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
NHKNCPHF_01940	1.56e-89	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NHKNCPHF_01941	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NHKNCPHF_01942	6.12e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHKNCPHF_01948	3.84e-257	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHKNCPHF_01949	1.04e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHKNCPHF_01950	2.74e-304	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NHKNCPHF_01951	2.15e-198	-	-	-	S	-	-	-	CHAP domain
NHKNCPHF_01952	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NHKNCPHF_01953	1.55e-128	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHKNCPHF_01954	3.74e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NHKNCPHF_01955	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHKNCPHF_01956	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHKNCPHF_01957	5.24e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NHKNCPHF_01958	1.89e-40	acpP_1	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHKNCPHF_01959	1.45e-235	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHKNCPHF_01960	1.89e-179	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NHKNCPHF_01961	7.11e-274	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NHKNCPHF_01962	5.55e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHKNCPHF_01963	4.11e-72	pcsB	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
NHKNCPHF_01964	2.05e-110	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
NHKNCPHF_01965	3.38e-157	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NHKNCPHF_01984	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHKNCPHF_01985	3.15e-126	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
NHKNCPHF_01986	9.1e-299	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHKNCPHF_01987	1.35e-300	-	3.5.2.6	-	V	ko:K01467	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01000	Beta-lactamase enzyme family
NHKNCPHF_01988	1.36e-05	-	-	-	-	-	-	-	-
NHKNCPHF_01989	3.9e-79	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
NHKNCPHF_01990	1.87e-53	yabO	-	-	J	-	-	-	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NHKNCPHF_01991	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHKNCPHF_01992	1.8e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHKNCPHF_01993	7.47e-259	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHKNCPHF_01994	1.4e-40	yyzM	-	-	S	-	-	-	Protein conserved in bacteria