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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NHFCAKPK_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHFCAKPK_00002	1.08e-170	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NHFCAKPK_00003	5.83e-274	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NHFCAKPK_00004	1.96e-103	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHFCAKPK_00005	1.5e-151	yoaK	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NHFCAKPK_00009	0.0	XK27_10405	-	-	S	-	-	-	Bacterial membrane protein YfhO
NHFCAKPK_00010	0.0	ykpA	-	-	S	-	-	-	abc transporter atp-binding protein
NHFCAKPK_00011	1.09e-192	XK27_10395	-	-	S	-	-	-	membrane
NHFCAKPK_00012	1.07e-240	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
NHFCAKPK_00013	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NHFCAKPK_00014	1.14e-255	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHFCAKPK_00015	2.94e-75	yaaA	-	-	S	-	-	-	S4 domain protein YaaA
NHFCAKPK_00016	3.13e-292	albE	-	-	S	-	-	-	Peptidase M16
NHFCAKPK_00017	5.06e-298	ymfH	-	-	S	-	-	-	Peptidase M16
NHFCAKPK_00018	1.58e-164	-	-	-	S	ko:K15539	-	ko00000	sequence-specific DNA binding
NHFCAKPK_00019	2.2e-117	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHFCAKPK_00020	4.31e-192	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHFCAKPK_00021	2.13e-194	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHFCAKPK_00022	1.25e-169	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHFCAKPK_00023	5.05e-102	lytE	-	-	M	-	-	-	LysM domain protein
NHFCAKPK_00024	1.02e-127	isaA	-	-	M	-	-	-	Immunodominant staphylococcal antigen A
NHFCAKPK_00025	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NHFCAKPK_00026	2.77e-271	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHFCAKPK_00027	1.43e-127	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
NHFCAKPK_00028	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHFCAKPK_00029	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NHFCAKPK_00030	1.77e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NHFCAKPK_00031	3.16e-313	dnaC	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NHFCAKPK_00032	6.16e-63	WQ51_01655	-	-	S	-	-	-	Biofilm formation stimulator VEG
NHFCAKPK_00033	1.25e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHFCAKPK_00034	5.32e-13	-	-	-	-	-	-	-	-
NHFCAKPK_00035	3.79e-71	XK27_04840	-	-	M	ko:K08987	-	ko00000	Membrane
NHFCAKPK_00036	1.14e-123	XK27_06935	-	-	K	-	-	-	transcriptional regulator
NHFCAKPK_00037	8.64e-261	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
NHFCAKPK_00038	3.59e-145	-	-	-	S	-	-	-	Putative adhesin
NHFCAKPK_00039	7.06e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
NHFCAKPK_00040	8.74e-69	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator, PadR family
NHFCAKPK_00041	3.34e-150	XK27_06885	-	-	L	-	-	-	hydrolase
NHFCAKPK_00045	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
NHFCAKPK_00046	1.52e-108	-	-	-	S	-	-	-	EcsC protein family
NHFCAKPK_00048	1.72e-167	-	-	-	-	-	-	-	-
NHFCAKPK_00049	1.22e-26	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NHFCAKPK_00050	3.57e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NHFCAKPK_00051	1.43e-276	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
NHFCAKPK_00052	0.000652	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system
NHFCAKPK_00053	6.64e-59	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHFCAKPK_00054	3.96e-116	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHFCAKPK_00055	3.45e-301	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NHFCAKPK_00057	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NHFCAKPK_00058	1.03e-213	XK27_01785	-	-	S	-	-	-	cog cog1284
NHFCAKPK_00059	4.42e-154	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NHFCAKPK_00060	2.09e-148	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHFCAKPK_00061	4.23e-115	-	-	-	K	-	-	-	acetyltransferase
NHFCAKPK_00062	7.68e-20	-	-	-	-	-	-	-	-
NHFCAKPK_00063	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
NHFCAKPK_00064	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHFCAKPK_00065	1.34e-62	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NHFCAKPK_00066	9.82e-92	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHFCAKPK_00067	9.75e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NHFCAKPK_00068	0.0	-	-	-	L	-	-	-	Transposase
NHFCAKPK_00069	1.73e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NHFCAKPK_00070	8.44e-300	rarA	-	-	L	ko:K07478	-	ko00000	ATPase related to the helicase subunit of the Holliday junction resolvase
NHFCAKPK_00072	8.68e-278	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NHFCAKPK_00073	1.95e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
NHFCAKPK_00074	4.61e-207	-	-	-	L	-	-	-	Replication initiation factor
NHFCAKPK_00075	4.55e-114	-	-	-	K	-	-	-	sequence-specific DNA binding
NHFCAKPK_00076	5.03e-105	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NHFCAKPK_00078	8.75e-183	-	-	-	S	-	-	-	Pfam:UPF0118
NHFCAKPK_00079	1.19e-73	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHFCAKPK_00080	4.9e-190	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHFCAKPK_00081	1.25e-115	flaR	-	-	F	-	-	-	topology modulation protein
NHFCAKPK_00082	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHFCAKPK_00083	6.56e-106	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHFCAKPK_00084	1.21e-47	-	-	-	S	-	-	-	MORN repeat protein
NHFCAKPK_00085	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase
NHFCAKPK_00086	7.25e-240	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHFCAKPK_00087	4.29e-64	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NHFCAKPK_00088	3.17e-142	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHFCAKPK_00089	2.13e-135	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NHFCAKPK_00090	6e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHFCAKPK_00091	5.06e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHFCAKPK_00092	8.13e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHFCAKPK_00093	1.21e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHFCAKPK_00094	9.44e-153	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHFCAKPK_00095	4.35e-94	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHFCAKPK_00096	6.2e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NHFCAKPK_00097	3.08e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHFCAKPK_00098	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHFCAKPK_00099	5.67e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHFCAKPK_00100	5.86e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHFCAKPK_00101	2.03e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHFCAKPK_00102	3.78e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHFCAKPK_00103	5.88e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHFCAKPK_00104	7.15e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHFCAKPK_00105	2.01e-103	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHFCAKPK_00106	9.89e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l30
NHFCAKPK_00107	8.47e-85	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NHFCAKPK_00108	8.65e-293	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHFCAKPK_00109	1.7e-148	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHFCAKPK_00110	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHFCAKPK_00111	3.26e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NHFCAKPK_00112	4.42e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHFCAKPK_00113	1.63e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHFCAKPK_00114	7.63e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHFCAKPK_00115	3.03e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l17
NHFCAKPK_00116	8.98e-311	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
NHFCAKPK_00118	8.52e-212	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	aldolase
NHFCAKPK_00121	1.37e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
NHFCAKPK_00122	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
NHFCAKPK_00123	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NHFCAKPK_00124	0.0	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NHFCAKPK_00126	6.92e-05	yebC	-	-	M	-	-	-	Membrane
NHFCAKPK_00127	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
NHFCAKPK_00128	1.83e-281	norN	-	-	V	-	-	-	Mate efflux family protein
NHFCAKPK_00129	1.87e-76	asp	-	-	S	-	-	-	cog cog1302
NHFCAKPK_00130	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
NHFCAKPK_00131	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
NHFCAKPK_00132	0.0	ilvB	2.2.1.6	-	EH	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
NHFCAKPK_00133	8.29e-100	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
NHFCAKPK_00134	2.19e-249	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NHFCAKPK_00135	1.65e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHFCAKPK_00136	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NHFCAKPK_00137	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHFCAKPK_00138	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHFCAKPK_00139	1.13e-90	-	-	-	S	-	-	-	cog cog4699
NHFCAKPK_00140	3.13e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NHFCAKPK_00141	1.48e-178	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NHFCAKPK_00142	1.1e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
NHFCAKPK_00143	2.8e-91	cglD	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	Competence protein
NHFCAKPK_00144	2.48e-21	-	-	-	NU	-	-	-	Type II secretory pathway pseudopilin
NHFCAKPK_00145	9.27e-93	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Competence protein ComGF
NHFCAKPK_00146	7.17e-17	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
NHFCAKPK_00147	1.32e-223	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
NHFCAKPK_00148	1.57e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHFCAKPK_00149	1.05e-36	lanR	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
NHFCAKPK_00150	1.47e-136	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
NHFCAKPK_00152	8.45e-121	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
NHFCAKPK_00153	2.63e-167	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHFCAKPK_00154	1.51e-259	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
NHFCAKPK_00156	5.78e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
NHFCAKPK_00158	4.53e-146	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHFCAKPK_00159	7e-243	yeeE	-	-	S	ko:K07112	-	ko00000	Sulphur transport
NHFCAKPK_00160	3.2e-49	yeeD	-	-	O	ko:K07112	-	ko00000	sulfur carrier activity
NHFCAKPK_00161	1.81e-85	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHFCAKPK_00162	1.99e-116	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHFCAKPK_00166	1.58e-200	rrmA	2.1.1.187	-	Q	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	methyltransferase
NHFCAKPK_00167	3.22e-165	-	-	-	S	ko:K07025	-	ko00000	HAD hydrolase, family IA, variant
NHFCAKPK_00168	3.08e-109	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHFCAKPK_00169	2.22e-279	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHFCAKPK_00170	8.09e-122	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHFCAKPK_00171	1.27e-149	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
NHFCAKPK_00172	9.25e-217	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NHFCAKPK_00173	1.34e-232	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NHFCAKPK_00174	2.37e-124	XK27_08585	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
NHFCAKPK_00175	1.49e-181	nirC_1	-	-	P	-	-	-	Formate nitrite transporter
NHFCAKPK_00176	3.61e-307	XK27_09615	-	-	C	ko:K19784	-	ko00000	reductase
NHFCAKPK_00177	3.33e-140	XK27_09620	-	-	S	-	-	-	FMN reductase (NADPH) activity
NHFCAKPK_00178	7.58e-98	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NHFCAKPK_00179	4.47e-98	-	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
NHFCAKPK_00180	1.77e-283	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHFCAKPK_00181	2.05e-163	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
NHFCAKPK_00182	3.77e-113	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
NHFCAKPK_00183	4.66e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
NHFCAKPK_00184	1.69e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHFCAKPK_00185	4.57e-154	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHFCAKPK_00186	0.0	amiA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NHFCAKPK_00187	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHFCAKPK_00188	1.6e-290	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	signal transduction protein with a C-terminal ATPase domain
NHFCAKPK_00189	7.66e-196	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHFCAKPK_00190	8.2e-261	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHFCAKPK_00191	2.95e-285	fasC	-	-	T	-	-	-	protein histidine kinase activity
NHFCAKPK_00192	3.11e-166	fasA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulator of the LytR AlgR family
NHFCAKPK_00193	2.89e-293	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHFCAKPK_00194	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase
NHFCAKPK_00195	9.69e-72	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NHFCAKPK_00196	4.24e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHFCAKPK_00197	7.54e-224	jag	-	-	S	ko:K06346	-	ko00000	RNA-binding protein
NHFCAKPK_00198	3.76e-126	-	-	-	K	-	-	-	Transcriptional regulator
NHFCAKPK_00199	1.3e-120	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-quinone reductase (modulator of drug activity B)
NHFCAKPK_00200	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
NHFCAKPK_00201	1.16e-287	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHFCAKPK_00214	6.07e-66	bta	1.8.1.8	-	CO	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	cell redox homeostasis
NHFCAKPK_00215	2.05e-76	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	thioesterase
NHFCAKPK_00216	1.18e-181	-	-	-	S	-	-	-	Macro domain protein
NHFCAKPK_00217	1.27e-66	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NHFCAKPK_00218	2.29e-92	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
NHFCAKPK_00219	2.16e-181	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
NHFCAKPK_00220	2.57e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NHFCAKPK_00221	8.34e-197	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHFCAKPK_00222	0.0	-	-	-	L	-	-	-	Transposase
NHFCAKPK_00224	4.19e-206	rsgA	3.1.3.100	-	G	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHFCAKPK_00225	1.15e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NHFCAKPK_00226	2.32e-145	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NHFCAKPK_00227	1.62e-229	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC domain protein
NHFCAKPK_00228	6.86e-228	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
NHFCAKPK_00229	7.91e-184	purR	-	-	F	ko:K09685	-	ko00000,ko03000	operon repressor
NHFCAKPK_00230	4.89e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NHFCAKPK_00231	4.66e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NHFCAKPK_00232	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHFCAKPK_00233	4.47e-231	gap	1.2.1.12	-	C	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
NHFCAKPK_00234	9.51e-283	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NHFCAKPK_00235	1.03e-111	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
NHFCAKPK_00236	9.18e-83	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
NHFCAKPK_00237	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NHFCAKPK_00238	6.18e-150	sle1	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	CHAP domain protein
NHFCAKPK_00239	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHFCAKPK_00240	4.54e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NHFCAKPK_00241	1.27e-151	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214, inactive homolog of metal-dependent proteases
NHFCAKPK_00242	1.21e-93	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NHFCAKPK_00243	7.79e-237	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHFCAKPK_00244	8.09e-145	XK27_12120	-	-	E	-	-	-	AzlC protein
NHFCAKPK_00245	6.6e-62	-	-	-	S	-	-	-	branched-chain amino acid
NHFCAKPK_00246	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHFCAKPK_00247	2.61e-148	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NHFCAKPK_00248	1.3e-199	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHFCAKPK_00249	1.18e-20	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NHFCAKPK_00250	4.82e-121	cvpA	-	-	S	ko:K03558	-	ko00000	toxin biosynthetic process
NHFCAKPK_00251	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHFCAKPK_00252	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHFCAKPK_00254	1.19e-33	-	-	-	-	-	-	-	-
NHFCAKPK_00256	4.83e-277	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
NHFCAKPK_00257	5.71e-53	XK27_05745	-	-	-	-	-	-	-
NHFCAKPK_00258	5.39e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NHFCAKPK_00259	2.61e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHFCAKPK_00260	4.1e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHFCAKPK_00262	8.39e-159	XK27_01040	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NHFCAKPK_00263	2.01e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	COG0598 Mg2 and Co2 transporters
NHFCAKPK_00264	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NHFCAKPK_00267	1.43e-37	blpT	-	-	-	-	-	-	-
NHFCAKPK_00268	1.28e-187	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	'abc transporter, ATP-binding protein
NHFCAKPK_00270	6.86e-255	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
NHFCAKPK_00271	3.59e-111	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NHFCAKPK_00272	8.59e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHFCAKPK_00273	1.75e-78	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	protein conserved in bacteria
NHFCAKPK_00274	8.95e-95	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHFCAKPK_00275	3.67e-227	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	Transcriptional regulator
NHFCAKPK_00276	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NHFCAKPK_00277	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHFCAKPK_00278	1.95e-219	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Fructokinase
NHFCAKPK_00279	8.11e-237	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NHFCAKPK_00281	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHFCAKPK_00282	3.37e-250	aroH	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NHFCAKPK_00283	3.53e-247	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NHFCAKPK_00284	2.5e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHFCAKPK_00285	3.87e-243	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHFCAKPK_00286	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHFCAKPK_00290	4.07e-43	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
NHFCAKPK_00291	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NHFCAKPK_00292	8.77e-203	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NHFCAKPK_00294	6.29e-219	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NHFCAKPK_00295	0.0	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
NHFCAKPK_00296	1.19e-175	yebC	-	-	M	-	-	-	Membrane
NHFCAKPK_00297	0.0	-	-	-	KT	-	-	-	response to antibiotic
NHFCAKPK_00298	5.33e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
NHFCAKPK_00299	5.57e-152	-	-	-	S	-	-	-	membrane
NHFCAKPK_00300	4.86e-98	mccF	-	-	V	-	-	-	LD-carboxypeptidase
NHFCAKPK_00301	1.06e-57	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
NHFCAKPK_00302	9.68e-251	mccF	-	-	V	-	-	-	LD-carboxypeptidase
NHFCAKPK_00303	0.0	-	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
NHFCAKPK_00305	8.38e-187	-	-	-	V	ko:K21397	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
NHFCAKPK_00308	1.12e-14	-	-	-	-	-	-	-	-
NHFCAKPK_00309	2.25e-286	dcuS	2.7.13.3	-	T	ko:K02476,ko:K07701,ko:K07706,ko:K11614	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHFCAKPK_00310	6.12e-297	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHFCAKPK_00311	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NHFCAKPK_00312	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NHFCAKPK_00313	5.77e-160	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
NHFCAKPK_00314	5.01e-170	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_00315	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NHFCAKPK_00316	2.37e-180	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHFCAKPK_00317	3.21e-285	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHFCAKPK_00318	2.57e-76	-	-	-	J	-	-	-	Membrane
NHFCAKPK_00319	8.91e-45	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
NHFCAKPK_00320	5.57e-81	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
NHFCAKPK_00321	6.18e-48	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
NHFCAKPK_00324	1.13e-133	-	-	-	-	-	-	-	-
NHFCAKPK_00325	1.09e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHFCAKPK_00326	5.32e-60	ftsL	-	-	D	-	-	-	cell division protein FtsL
NHFCAKPK_00327	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
NHFCAKPK_00328	1.9e-234	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHFCAKPK_00329	3.25e-301	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NHFCAKPK_00332	6.28e-315	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NHFCAKPK_00333	1.65e-112	yutD	-	-	J	-	-	-	protein conserved in bacteria
NHFCAKPK_00334	7.84e-286	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NHFCAKPK_00335	5.25e-118	XK27_09885	-	-	V	-	-	-	Glycopeptide antibiotics resistance protein
NHFCAKPK_00338	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_00339	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_00348	2.41e-46	spiA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	sequence-specific DNA binding
NHFCAKPK_00351	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NHFCAKPK_00352	8.98e-193	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NHFCAKPK_00353	1.08e-121	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
NHFCAKPK_00354	1.22e-175	cppA	-	-	E	-	-	-	CppA N-terminal
NHFCAKPK_00355	7.91e-219	-	-	-	V	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding proteins
NHFCAKPK_00357	1.4e-94	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHFCAKPK_00358	1.44e-182	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	carbonic anhydrase
NHFCAKPK_00359	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	formate acetyltransferase'
NHFCAKPK_00360	3.72e-259	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHFCAKPK_00362	1.15e-196	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
NHFCAKPK_00363	7.25e-208	yxeN	-	-	P	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_00364	3.11e-166	tcyN	3.6.3.21	-	E	ko:K02028,ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHFCAKPK_00365	3.64e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4059)
NHFCAKPK_00366	1.87e-217	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHFCAKPK_00367	2.12e-119	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
NHFCAKPK_00368	3.77e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHFCAKPK_00369	2.51e-239	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NHFCAKPK_00370	8.06e-232	ytqA	-	-	S	ko:K07139	-	ko00000	radical SAM protein
NHFCAKPK_00371	3.95e-121	mraW1	-	-	J	-	-	-	(SAM)-dependent
NHFCAKPK_00373	0.0	nhaP1	-	-	P	ko:K03316	-	ko00000	NhaP-type Na H and K H antiporters
NHFCAKPK_00374	7.29e-32	-	-	-	-	-	-	-	-
NHFCAKPK_00376	3.39e-181	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHFCAKPK_00377	1.36e-302	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	COG1253 Hemolysins and related proteins containing CBS domains
NHFCAKPK_00379	4.91e-202	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NHFCAKPK_00381	6.2e-98	XK27_03180	-	-	T	-	-	-	universal stress protein
NHFCAKPK_00382	4.15e-300	aspC	2.6.1.2, 2.6.1.66	-	E	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NHFCAKPK_00383	2.12e-180	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NHFCAKPK_00384	3.53e-129	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	isochorismatase
NHFCAKPK_00385	3.94e-189	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
NHFCAKPK_00386	4.28e-120	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHFCAKPK_00387	0.0	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NHFCAKPK_00388	1.5e-276	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
NHFCAKPK_00389	8.06e-201	-	-	-	H	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
NHFCAKPK_00390	4.23e-241	-	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NHFCAKPK_00391	4.31e-293	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NHFCAKPK_00392	1.77e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHFCAKPK_00393	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHFCAKPK_00394	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHFCAKPK_00395	1.11e-79	-	-	-	-	-	-	-	-
NHFCAKPK_00396	2.74e-242	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
NHFCAKPK_00397	3.45e-192	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHFCAKPK_00398	2.61e-127	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
NHFCAKPK_00399	2.67e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NHFCAKPK_00400	4.57e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
NHFCAKPK_00401	6.44e-152	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHFCAKPK_00402	1.86e-135	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
NHFCAKPK_00403	3.42e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHFCAKPK_00404	2.6e-178	XK27_06665	-	-	Q	-	-	-	Methyltransferase domain protein
NHFCAKPK_00405	3.23e-249	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NHFCAKPK_00406	1.88e-52	yefM	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
NHFCAKPK_00407	8.54e-58	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	Addiction module toxin, Txe YoeB family
NHFCAKPK_00408	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	ATP-dependent Clp protease ATP-binding subunit
NHFCAKPK_00409	1.53e-52	-	-	-	-	-	-	-	-
NHFCAKPK_00411	3.56e-94	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NHFCAKPK_00412	8.31e-169	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_00413	2.45e-222	XK27_05910	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
NHFCAKPK_00414	2.95e-197	ytmP	-	-	M	-	-	-	Phosphotransferase
NHFCAKPK_00415	8.79e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHFCAKPK_00417	4.01e-281	ytfP	-	-	S	ko:K07007	-	ko00000	Flavoprotein
NHFCAKPK_00418	0.0	ilvD	4.2.1.9	-	E	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
NHFCAKPK_00419	1.09e-83	XK27_02560	-	-	S	-	-	-	cog cog2151
NHFCAKPK_00420	5.18e-76	WQ51_02910	-	-	S	-	-	-	Protein of unknown function, DUF536
NHFCAKPK_00421	2.53e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NHFCAKPK_00422	2.26e-164	-	-	-	K	-	-	-	transcriptional regulator, MerR family
NHFCAKPK_00423	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_00424	1.59e-160	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_00426	5.11e-57	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NHFCAKPK_00427	1.12e-66	-	-	-	-	-	-	-	-
NHFCAKPK_00428	5.13e-58	-	-	-	-	-	-	-	-
NHFCAKPK_00429	3.82e-102	-	-	-	-	-	-	-	-
NHFCAKPK_00431	0.0	-	-	-	-	-	-	-	-
NHFCAKPK_00432	0.0	-	2.4.1.12	GT2	M	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
NHFCAKPK_00433	6.04e-217	-	-	-	M	-	-	-	COG0463, glycosyltransferases involved in cell wall biogenesis
NHFCAKPK_00434	5.6e-25	-	-	-	M	-	-	-	COG0463, glycosyltransferases involved in cell wall biogenesis
NHFCAKPK_00435	5.34e-220	-	-	-	T	-	-	-	Diguanylate cyclase
NHFCAKPK_00436	1.18e-45	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NHFCAKPK_00437	9.35e-28	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
NHFCAKPK_00438	6.65e-61	-	-	-	-	-	-	-	-
NHFCAKPK_00439	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
NHFCAKPK_00440	5.38e-76	-	-	-	-	-	-	-	-
NHFCAKPK_00441	2.01e-53	-	4.2.99.21	-	E	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Chorismate mutase type II
NHFCAKPK_00442	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHFCAKPK_00443	4.1e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	anthranilate
NHFCAKPK_00444	4.99e-227	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NHFCAKPK_00445	9.27e-172	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
NHFCAKPK_00446	3.59e-127	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the TrpF family
NHFCAKPK_00447	1.22e-291	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NHFCAKPK_00448	4.13e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NHFCAKPK_00450	1.28e-98	copY	-	-	K	-	-	-	negative regulation of transcription, DNA-templated
NHFCAKPK_00451	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NHFCAKPK_00452	2.72e-42	copZ	-	-	P	-	-	-	Heavy metal-associated domain protein
NHFCAKPK_00453	8.85e-244	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NHFCAKPK_00454	1.42e-147	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_00455	3.24e-148	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_00456	4.44e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHFCAKPK_00457	1.1e-198	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NHFCAKPK_00461	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHFCAKPK_00462	5.01e-150	ywaF	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
NHFCAKPK_00464	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHFCAKPK_00465	1.71e-124	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter
NHFCAKPK_00466	7.5e-83	yjqA	-	-	S	-	-	-	Bacterial PH domain
NHFCAKPK_00467	1.5e-200	corA	-	-	P	-	-	-	CorA-like protein
NHFCAKPK_00468	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHFCAKPK_00469	2.9e-56	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
NHFCAKPK_00470	4.13e-179	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase
NHFCAKPK_00471	4.39e-198	-	-	-	G	-	-	-	Polysaccharide deacetylase
NHFCAKPK_00472	2.92e-182	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
NHFCAKPK_00473	4.46e-126	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
NHFCAKPK_00474	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NHFCAKPK_00475	4.28e-292	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHFCAKPK_00476	2.79e-125	XK27_07830	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase GNAT Family
NHFCAKPK_00477	1.5e-295	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
NHFCAKPK_00478	4.94e-212	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NHFCAKPK_00479	7.44e-207	rbn	-	-	E	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NHFCAKPK_00480	3.45e-111	ccl	-	-	S	-	-	-	cog cog4708
NHFCAKPK_00481	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHFCAKPK_00482	1.06e-234	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NHFCAKPK_00484	4.81e-227	yfjR	-	-	K	-	-	-	regulation of single-species biofilm formation
NHFCAKPK_00486	6.75e-95	-	-	-	S	-	-	-	QueT transporter
NHFCAKPK_00487	5.11e-204	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NHFCAKPK_00489	9.1e-79	XK27_00915	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHFCAKPK_00490	1.99e-15	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
NHFCAKPK_00491	1.12e-211	tehB	2.1.1.265	-	PQ	ko:K16868	-	ko00000,ko01000	tellurite resistance protein tehb
NHFCAKPK_00493	1.58e-235	-	-	-	O	-	-	-	protein import
NHFCAKPK_00494	3.89e-159	agrA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
NHFCAKPK_00495	4.6e-269	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHFCAKPK_00497	1.87e-57	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NHFCAKPK_00498	3.71e-49	ylqC	-	-	L	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NHFCAKPK_00499	8.78e-301	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NHFCAKPK_00500	0.0	ydaO	-	-	E	-	-	-	amino acid
NHFCAKPK_00501	4.02e-129	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	gtp cyclohydrolase
NHFCAKPK_00502	7.43e-186	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NHFCAKPK_00503	0.0	amy	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NHFCAKPK_00504	2.9e-79	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NHFCAKPK_00505	2.77e-98	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NHFCAKPK_00506	7.3e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
NHFCAKPK_00507	1.54e-269	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHFCAKPK_00508	4.03e-179	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
NHFCAKPK_00509	3.07e-167	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component II
NHFCAKPK_00510	7.79e-262	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	spermidine putrescine ABC transporter
NHFCAKPK_00511	1.37e-195	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
NHFCAKPK_00512	1.37e-92	gloA	4.4.1.5	-	E	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Lactoylglutathione lyase
NHFCAKPK_00513	3.47e-193	-	-	-	GK	-	-	-	ROK family
NHFCAKPK_00514	4.21e-266	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NHFCAKPK_00515	7.39e-132	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
NHFCAKPK_00516	1.19e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHFCAKPK_00517	3.28e-93	ogt	2.1.1.63, 3.2.2.20	-	L	ko:K00567,ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
NHFCAKPK_00518	1.19e-77	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
NHFCAKPK_00520	2.4e-73	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Effector of murein hydrolase LrgA
NHFCAKPK_00521	6.23e-149	lrgB	-	-	M	-	-	-	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NHFCAKPK_00522	1.71e-125	-	-	-	S	-	-	-	IA, variant 1
NHFCAKPK_00523	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHFCAKPK_00524	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHFCAKPK_00525	5.64e-144	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	phosphoserine phosphatase
NHFCAKPK_00527	1.65e-190	-	-	-	EG	-	-	-	Permeases of the drug metabolite transporter (DMT) superfamily
NHFCAKPK_00529	8.26e-80	ycaO	-	-	O	ko:K06889,ko:K07397,ko:K09136	-	ko00000,ko03009	OsmC-like protein
NHFCAKPK_00530	2.33e-81	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein possibly involved in aromatic compounds catabolism
NHFCAKPK_00531	2.83e-08	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
NHFCAKPK_00532	1.27e-163	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NHFCAKPK_00533	9.86e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
NHFCAKPK_00534	7.8e-315	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHFCAKPK_00535	5.23e-25	XK27_00735	-	-	-	-	-	-	-
NHFCAKPK_00536	4.14e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHFCAKPK_00537	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems periplasmic component domain
NHFCAKPK_00538	9.87e-211	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
NHFCAKPK_00540	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHFCAKPK_00542	3.05e-109	XK27_04400	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	Nudix family
NHFCAKPK_00543	2.19e-182	XK27_04395	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter
NHFCAKPK_00544	3.11e-177	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NHFCAKPK_00545	1.12e-268	arcT	-	-	E	-	-	-	Aminotransferase
NHFCAKPK_00546	3.73e-171	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NHFCAKPK_00547	8.61e-28	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NHFCAKPK_00548	1.21e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHFCAKPK_00549	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHFCAKPK_00550	2.49e-256	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHFCAKPK_00551	1.43e-73	yitW	-	-	K	-	-	-	metal-sulfur cluster biosynthetic enzyme
NHFCAKPK_00552	4.4e-217	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	COG0463, glycosyltransferases involved in cell wall biogenesis
NHFCAKPK_00553	0.0	-	-	-	S	-	-	-	Glucosyl transferase GtrII
NHFCAKPK_00554	5.74e-205	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NHFCAKPK_00555	8.15e-285	-	-	-	S	-	-	-	membrane protein involved in the export of O-antigen and teichoic acid
NHFCAKPK_00556	8.21e-200	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
NHFCAKPK_00557	5.63e-227	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NHFCAKPK_00558	2.1e-163	arnC	-	-	M	ko:K00786	-	ko00000,ko01000	group 2 family protein
NHFCAKPK_00559	1.68e-58	-	-	-	S	ko:K09153	-	ko00000	Uncharacterized conserved protein (DUF2304)
NHFCAKPK_00560	7.51e-193	-	-	-	S	-	-	-	Glycosyltransferase group 2 family protein
NHFCAKPK_00561	1e-122	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHFCAKPK_00562	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NHFCAKPK_00563	2.84e-280	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
NHFCAKPK_00564	2.38e-291	-	-	GT4	M	ko:K00754	-	ko00000,ko01000	transferase activity, transferring glycosyl groups
NHFCAKPK_00565	3.32e-288	rgpA	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
NHFCAKPK_00566	1.05e-226	rgpB	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
NHFCAKPK_00567	1.09e-181	-	-	-	GM	ko:K01992,ko:K09690,ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
NHFCAKPK_00568	7.55e-285	rgpD	3.6.3.40	-	P	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NHFCAKPK_00569	0.0	rgpF	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
NHFCAKPK_00570	5.39e-153	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
NHFCAKPK_00571	8.7e-165	-	-	-	T	ko:K07010	-	ko00000,ko01002	peptidase C26
NHFCAKPK_00572	6.37e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NHFCAKPK_00573	1.25e-78	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
NHFCAKPK_00574	1.02e-260	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
NHFCAKPK_00575	3.37e-224	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHFCAKPK_00576	3.35e-131	yjbK	-	-	S	-	-	-	Adenylate cyclase
NHFCAKPK_00577	4.08e-154	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Gtp pyrophosphokinase
NHFCAKPK_00578	4.66e-195	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHFCAKPK_00579	1.22e-218	yjbO	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NHFCAKPK_00580	2.66e-223	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
NHFCAKPK_00581	0.0	amiA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NHFCAKPK_00582	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
NHFCAKPK_00583	0.0	amiC	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_00584	1.92e-211	amiD	-	-	P	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_00585	1.34e-256	amiE	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHFCAKPK_00586	4.76e-217	amiF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHFCAKPK_00587	5.03e-163	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
NHFCAKPK_00588	2.9e-159	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_00589	3.31e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional
NHFCAKPK_00590	2.49e-185	-	-	-	S	-	-	-	overlaps another CDS with the same product name
NHFCAKPK_00591	2.91e-188	XK27_02985	-	-	S	-	-	-	overlaps another CDS with the same product name
NHFCAKPK_00592	2.08e-262	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHFCAKPK_00593	4.34e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NHFCAKPK_00594	1.37e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-directed 5'-3' RNA polymerase activity
NHFCAKPK_00595	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHFCAKPK_00596	1.17e-218	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHFCAKPK_00597	1.18e-307	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHFCAKPK_00598	3.65e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NHFCAKPK_00599	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NHFCAKPK_00600	3.82e-138	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion transport protein
NHFCAKPK_00601	3.48e-151	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Membrane
NHFCAKPK_00602	1.2e-219	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHFCAKPK_00603	1.9e-146	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHFCAKPK_00606	3.73e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHFCAKPK_00607	1.98e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NHFCAKPK_00608	6.7e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NHFCAKPK_00609	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NHFCAKPK_00610	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
NHFCAKPK_00611	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NHFCAKPK_00612	8.89e-251	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NHFCAKPK_00613	2.68e-228	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	glucose-1-phosphate adenylyltransferase
NHFCAKPK_00614	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
NHFCAKPK_00615	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NHFCAKPK_00616	9.32e-131	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
NHFCAKPK_00617	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
NHFCAKPK_00619	0.0	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
NHFCAKPK_00620	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
NHFCAKPK_00621	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
NHFCAKPK_00622	3.58e-183	XK27_10075	-	-	S	-	-	-	abc transporter atp-binding protein
NHFCAKPK_00623	1.4e-87	XK27_10075	-	-	S	-	-	-	abc transporter atp-binding protein
NHFCAKPK_00625	0.0	-	-	-	M	-	-	-	domain protein
NHFCAKPK_00626	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
NHFCAKPK_00627	0.0	-	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	signal peptide protein, YSIRK family
NHFCAKPK_00628	0.0	-	-	-	GM	-	-	-	domain, Protein
NHFCAKPK_00629	6.1e-276	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NHFCAKPK_00630	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	ATPase involved in DNA repair
NHFCAKPK_00631	0.0	-	-	-	M	-	-	-	family 8
NHFCAKPK_00632	2.44e-269	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the accessory SecA2 SecY2 system specifically required for export of
NHFCAKPK_00633	0.0	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
NHFCAKPK_00634	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system protein Asp2
NHFCAKPK_00635	1.59e-99	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec system protein Asp3
NHFCAKPK_00636	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHFCAKPK_00637	0.0	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NHFCAKPK_00638	3.26e-309	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NHFCAKPK_00639	3.27e-24	-	-	-	S	-	-	-	Accessory secretory protein Sec Asp4
NHFCAKPK_00640	3.67e-23	-	-	-	S	-	-	-	Accessory secretory protein Sec, Asp5
NHFCAKPK_00641	8.46e-239	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NHFCAKPK_00642	0.0	sraP	-	-	UW	ko:K18491,ko:K21449	ko04550,map04550	ko00000,ko00001,ko02000,ko03000	Hep Hag repeat protein
NHFCAKPK_00652	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
NHFCAKPK_00653	0.0	-	3.5.1.28	-	M	ko:K01448,ko:K13733,ko:K20276	ko01503,ko02024,ko05100,map01503,map02024,map05100	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	domain protein
NHFCAKPK_00654	4.29e-174	-	-	-	S	-	-	-	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
NHFCAKPK_00655	9.51e-125	maa	2.3.1.79	-	GK	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
NHFCAKPK_00656	2.08e-87	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NHFCAKPK_00657	3.88e-302	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	Major facilitator Superfamily
NHFCAKPK_00658	8.23e-169	-	-	-	S	-	-	-	CAAX protease self-immunity
NHFCAKPK_00659	2.23e-151	mleR	-	-	K	-	-	-	malolactic fermentation system
NHFCAKPK_00660	6.29e-63	-	-	-	K	-	-	-	Helix-turn-helix
NHFCAKPK_00661	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
NHFCAKPK_00662	2.6e-208	mleP	-	-	S	ko:K07088	-	ko00000	auxin efflux carrier
NHFCAKPK_00663	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHFCAKPK_00665	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
NHFCAKPK_00666	0.0	-	-	-	S	-	-	-	dextransucrase activity
NHFCAKPK_00667	0.0	-	-	-	S	-	-	-	dextransucrase activity
NHFCAKPK_00668	2.86e-241	-	-	-	S	-	-	-	dextransucrase activity
NHFCAKPK_00669	2.6e-55	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
NHFCAKPK_00670	0.0	tcdB	-	-	M	ko:K11063	ko02024,map02024	ko00000,ko00001,ko02042	Putative cell wall binding repeat
NHFCAKPK_00671	1.68e-199	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NHFCAKPK_00672	4.78e-126	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NHFCAKPK_00673	1.92e-97	-	-	-	-	-	-	-	-
NHFCAKPK_00674	0.0	-	-	-	S	-	-	-	dextransucrase activity
NHFCAKPK_00675	4.33e-317	-	-	-	S	-	-	-	dextransucrase activity
NHFCAKPK_00676	1.26e-122	-	-	-	S	-	-	-	dextransucrase activity
NHFCAKPK_00677	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
NHFCAKPK_00678	0.0	-	-	-	S	-	-	-	dextransucrase activity
NHFCAKPK_00679	1.04e-82	-	-	-	-	-	-	-	-
NHFCAKPK_00681	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
NHFCAKPK_00682	1.72e-10	-	-	-	S	-	-	-	Enterocin A Immunity
NHFCAKPK_00683	2.69e-137	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
NHFCAKPK_00684	5.78e-57	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NHFCAKPK_00685	1.56e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
NHFCAKPK_00686	4.4e-246	mccF	-	-	V	-	-	-	LD-carboxypeptidase
NHFCAKPK_00687	1.57e-11	-	-	-	S	-	-	-	Enterocin A Immunity
NHFCAKPK_00688	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NHFCAKPK_00689	1.25e-46	-	-	-	S	-	-	-	Immunity protein 41
NHFCAKPK_00690	1.21e-287	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
NHFCAKPK_00691	7.12e-229	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dihydroxyacetone kinase
NHFCAKPK_00692	1.29e-119	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dihydroxyacetone kinase
NHFCAKPK_00693	4.72e-76	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	dihydroxyacetone kinase, phosphotransfer subunit
NHFCAKPK_00694	4.48e-231	XK27_10475	-	-	S	-	-	-	oxidoreductase
NHFCAKPK_00695	1.13e-255	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	glycerol dehydrogenase
NHFCAKPK_00697	0.0	XK27_07020	-	-	S	-	-	-	Belongs to the UPF0371 family
NHFCAKPK_00698	1.26e-272	vex1	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
NHFCAKPK_00699	1.44e-139	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_00700	1.59e-304	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
NHFCAKPK_00701	1.75e-148	vncR	-	-	K	-	-	-	Response regulator receiver domain protein
NHFCAKPK_00702	1.73e-289	vncS	2.7.13.3	-	T	ko:K10819	-	ko00000,ko01000	Histidine kinase
NHFCAKPK_00703	1.05e-59	-	-	-	L	-	-	-	transposase activity
NHFCAKPK_00704	3.85e-194	-	-	-	L	-	-	-	Integrase core domain
NHFCAKPK_00705	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	COG0366 Glycosidases
NHFCAKPK_00706	9.51e-68	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NHFCAKPK_00707	3.3e-161	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
NHFCAKPK_00708	2.2e-150	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
NHFCAKPK_00709	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
NHFCAKPK_00710	1.64e-130	-	-	-	S	-	-	-	Abortive infection C-terminus
NHFCAKPK_00711	1.33e-241	-	-	-	-	-	-	-	-
NHFCAKPK_00712	1.28e-188	-	-	-	K	-	-	-	AraC family transcriptional regulator
NHFCAKPK_00713	0.0	aga	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NHFCAKPK_00714	1.02e-190	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NHFCAKPK_00715	1.15e-282	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHFCAKPK_00716	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDPglucose--hexose-1-phosphate uridylyltransferase
NHFCAKPK_00717	4.24e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NHFCAKPK_00718	1.89e-254	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NHFCAKPK_00719	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	transporter
NHFCAKPK_00720	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
NHFCAKPK_00721	1.48e-269	-	-	-	S	-	-	-	Tetratricopeptide repeat
NHFCAKPK_00722	4.18e-201	yvgN	-	-	C	-	-	-	reductase
NHFCAKPK_00723	1.47e-41	XK27_10490	-	-	-	-	-	-	-
NHFCAKPK_00724	2.67e-52	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	nuclease activity
NHFCAKPK_00725	1.65e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NHFCAKPK_00726	1.1e-143	yodC	-	-	C	-	-	-	nitroreductase
NHFCAKPK_00727	5.05e-162	-	-	-	T	-	-	-	Xre family transcriptional regulator
NHFCAKPK_00728	1.22e-192	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
NHFCAKPK_00729	5.28e-160	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHFCAKPK_00730	2.09e-214	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_00731	2.85e-286	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHFCAKPK_00732	5.43e-196	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NHFCAKPK_00733	8.17e-98	ywnA_2	-	-	K	-	-	-	Transcriptional regulator
NHFCAKPK_00734	6.1e-192	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
NHFCAKPK_00735	8.17e-141	XK27_02070	-	-	S	ko:K07078	-	ko00000	nitroreductase
NHFCAKPK_00736	7.04e-218	ydhF	-	-	S	-	-	-	Aldo keto reductase
NHFCAKPK_00737	2.56e-123	-	-	-	K	-	-	-	WHG domain
NHFCAKPK_00738	1.5e-158	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_00739	5.08e-262	-	-	-	P	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHFCAKPK_00742	1.97e-56	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
NHFCAKPK_00743	3.95e-108	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
NHFCAKPK_00744	1.41e-220	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
NHFCAKPK_00745	1.17e-211	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NHFCAKPK_00746	1.59e-146	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_00747	1.12e-145	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
NHFCAKPK_00748	3.26e-176	tcyC2	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHFCAKPK_00749	0.0	-	-	-	S	-	-	-	dextransucrase activity
NHFCAKPK_00750	3e-283	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
NHFCAKPK_00751	4.87e-66	-	-	-	P	-	-	-	Protein conserved in bacteria
NHFCAKPK_00752	2.15e-261	-	-	-	S	-	-	-	Carbohydrate-binding domain-containing protein Cthe_2159
NHFCAKPK_00753	3.08e-31	-	-	-	S	-	-	-	CsbD-like
NHFCAKPK_00754	7.05e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
NHFCAKPK_00755	4.7e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
NHFCAKPK_00756	8.71e-231	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NHFCAKPK_00757	3.68e-295	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NHFCAKPK_00758	3.72e-238	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHFCAKPK_00760	2.88e-307	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
NHFCAKPK_00761	5.58e-184	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
NHFCAKPK_00762	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	(ABC) transporter
NHFCAKPK_00763	2.43e-283	pbuX	-	-	F	ko:K16169	-	ko00000,ko02000	xanthine permease
NHFCAKPK_00764	2.08e-126	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHFCAKPK_00765	6.96e-41	-	-	-	-	-	-	-	-
NHFCAKPK_00766	3.03e-158	graR	-	-	KT	ko:K19082	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHFCAKPK_00767	7.87e-219	-	-	-	T	-	-	-	Histidine kinase
NHFCAKPK_00768	2.57e-172	yxdL	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NHFCAKPK_00769	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
NHFCAKPK_00770	1.17e-120	XK27_05000	-	-	S	ko:K06940	-	ko00000	metal cluster binding
NHFCAKPK_00773	1.05e-196	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_00774	2.38e-169	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transporter
NHFCAKPK_00775	2.19e-105	-	-	-	F	-	-	-	cytidine deaminase activity
NHFCAKPK_00776	5.66e-57	yocS	-	-	S	ko:K03453	-	ko00000	Transporter
NHFCAKPK_00777	3.73e-125	yocS	-	-	S	ko:K03453	-	ko00000	Transporter
NHFCAKPK_00780	3.42e-202	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	'abc transporter, ATP-binding protein
NHFCAKPK_00781	2.04e-170	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NHFCAKPK_00782	8.39e-239	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHFCAKPK_00783	2.71e-130	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHFCAKPK_00784	3.05e-256	-	-	-	S	-	-	-	Protein of unknown function DUF262
NHFCAKPK_00785	5.64e-152	-	-	-	S	-	-	-	Protein of unknown function DUF262
NHFCAKPK_00786	1.49e-112	yfjR	-	-	K	-	-	-	regulation of single-species biofilm formation
NHFCAKPK_00789	1.51e-235	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NHFCAKPK_00790	1.04e-181	M1-956	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHFCAKPK_00791	3.14e-182	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHFCAKPK_00792	1.7e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NHFCAKPK_00793	2.78e-105	-	-	-	-	-	-	-	-
NHFCAKPK_00794	4.85e-59	-	-	-	-	-	-	-	-
NHFCAKPK_00795	4.57e-193	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
NHFCAKPK_00796	2.34e-126	Z012_04635	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
NHFCAKPK_00797	5.32e-140	-	-	-	F	ko:K09702	-	ko00000	Protein of unknown function (DUF1349)
NHFCAKPK_00798	5.21e-100	-	-	-	S	-	-	-	RDD family
NHFCAKPK_00799	0.0	-	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NHFCAKPK_00800	6.66e-278	-	-	-	H	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHFCAKPK_00801	1.45e-56	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system galactitol-specific IIB component
NHFCAKPK_00802	4.28e-281	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
NHFCAKPK_00803	5.73e-158	tktN	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose-5-phosphate synthase
NHFCAKPK_00804	1.93e-156	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
NHFCAKPK_00805	4.58e-189	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
NHFCAKPK_00806	2.7e-155	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
NHFCAKPK_00807	5.04e-164	yfnB	3.8.1.2	-	E	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	hydrolase
NHFCAKPK_00808	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHFCAKPK_00809	6.34e-48	-	-	-	P	ko:K10716	-	ko00000,ko02000	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NHFCAKPK_00810	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHFCAKPK_00811	8.2e-112	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase
NHFCAKPK_00812	0.0	clsA_1	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHFCAKPK_00813	2.24e-160	-	-	-	L	-	-	-	DNA alkylation repair enzyme
NHFCAKPK_00814	4.13e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHFCAKPK_00815	3.65e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHFCAKPK_00816	6.2e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHFCAKPK_00817	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NHFCAKPK_00818	2.28e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHFCAKPK_00819	3.73e-121	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHFCAKPK_00820	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHFCAKPK_00822	6.52e-75	nrdD_1	1.1.98.6, 1.17.4.1	-	F	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleoside-triphosphate reductase
NHFCAKPK_00823	1.35e-300	ycxD	-	-	K	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHFCAKPK_00825	1.29e-106	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NHFCAKPK_00826	1.78e-184	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Belongs to the pyridoxine kinase family
NHFCAKPK_00827	2.1e-104	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NHFCAKPK_00828	0.0	yheS_1	-	-	S	-	-	-	abc transporter atp-binding protein
NHFCAKPK_00829	0.0	noxE	-	-	P	-	-	-	NADH oxidase
NHFCAKPK_00830	8.02e-230	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NHFCAKPK_00831	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHFCAKPK_00832	6.26e-169	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
NHFCAKPK_00833	5.25e-94	ywkD	-	-	E	ko:K08234	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
NHFCAKPK_00834	3e-206	ypuA	-	-	S	-	-	-	secreted protein
NHFCAKPK_00835	1.01e-290	mntH_2	-	-	P	-	-	-	Mn2 and Fe2 transporters of the NRAMP family
NHFCAKPK_00836	4.26e-221	-	-	-	L	ko:K07482	-	ko00000	Integrase
NHFCAKPK_00837	3.52e-61	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
NHFCAKPK_00838	2.85e-214	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NHFCAKPK_00839	4.8e-224	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
NHFCAKPK_00840	3.43e-191	gst	-	-	O	ko:K11209	-	ko00000,ko01000	Glutathione S-transferase
NHFCAKPK_00841	2.7e-232	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NHFCAKPK_00842	6e-142	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NHFCAKPK_00843	4.58e-247	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHFCAKPK_00844	1.01e-186	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHFCAKPK_00845	3.56e-133	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHFCAKPK_00846	6.31e-292	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHFCAKPK_00847	8.65e-228	-	-	-	S	-	-	-	37-kD nucleoid-associated bacterial protein
NHFCAKPK_00848	1.45e-126	pvaA	-	-	M	ko:K02395	-	ko00000,ko02035	lytic transglycosylase activity
NHFCAKPK_00849	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
NHFCAKPK_00850	0.0	XK27_10035	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
NHFCAKPK_00851	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHFCAKPK_00852	4.18e-301	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Membrane protein involved in D-alanine export
NHFCAKPK_00853	7.07e-48	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHFCAKPK_00854	4.96e-308	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NHFCAKPK_00855	1.8e-113	-	-	-	G	-	-	-	Citrate lyase beta subunit
NHFCAKPK_00856	4.77e-94	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
NHFCAKPK_00857	0.0	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
NHFCAKPK_00858	1.46e-114	-	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
NHFCAKPK_00859	2.17e-100	-	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
NHFCAKPK_00860	8.87e-117	-	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
NHFCAKPK_00861	2.49e-209	yceH	-	-	P	-	-	-	Belongs to the TelA family
NHFCAKPK_00862	1.45e-251	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
NHFCAKPK_00863	2.22e-182	-	-	-	J	-	-	-	Phosphoribosyl transferase (PRTase)
NHFCAKPK_00864	2.55e-144	-	-	-	F	-	-	-	TRSP domain C terminus to PRTase_2
NHFCAKPK_00865	0.0	pabB	2.6.1.85, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	ko00000,ko00001,ko01000,ko01007	component I
NHFCAKPK_00867	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NHFCAKPK_00868	5.52e-207	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	reductase
NHFCAKPK_00869	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
NHFCAKPK_00870	7.19e-119	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NHFCAKPK_00871	8.28e-118	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHFCAKPK_00872	4.22e-145	coaB	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	Phosphopantothenate-cysteine ligase
NHFCAKPK_00873	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
NHFCAKPK_00874	1.14e-152	ciaR	-	-	T	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHFCAKPK_00875	1.18e-308	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHFCAKPK_00876	1.25e-39	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NHFCAKPK_00877	8.59e-217	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NHFCAKPK_00878	5.11e-133	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase small domain protein
NHFCAKPK_00879	4.95e-290	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NHFCAKPK_00880	1.17e-143	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NHFCAKPK_00881	8.58e-85	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NHFCAKPK_00882	2.01e-244	-	-	-	S	ko:K07335	-	ko00000	membrane
NHFCAKPK_00883	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NHFCAKPK_00884	2.59e-235	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHFCAKPK_00885	3.89e-216	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHFCAKPK_00886	2.72e-149	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
NHFCAKPK_00887	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NHFCAKPK_00888	4.97e-102	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
NHFCAKPK_00889	6.82e-273	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NHFCAKPK_00890	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NHFCAKPK_00892	4.7e-251	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHFCAKPK_00893	9.11e-84	aldR	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
NHFCAKPK_00894	1.3e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NHFCAKPK_00895	1.17e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
NHFCAKPK_00896	5.89e-171	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NHFCAKPK_00897	5.6e-123	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NHFCAKPK_00898	1.6e-274	-	-	-	D	-	-	-	nuclear chromosome segregation
NHFCAKPK_00899	2.87e-171	yejC	-	-	S	-	-	-	cyclic nucleotide-binding protein
NHFCAKPK_00900	5.72e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NHFCAKPK_00901	1.51e-232	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NHFCAKPK_00902	6.93e-207	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NHFCAKPK_00903	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NHFCAKPK_00904	9.64e-183	XK27_10720	-	-	D	-	-	-	peptidase activity
NHFCAKPK_00905	0.0	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NHFCAKPK_00908	1.61e-212	yeiH	-	-	S	-	-	-	Membrane
NHFCAKPK_00909	3.26e-163	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	muramidase
NHFCAKPK_00910	8.86e-214	cpsY	-	-	K	-	-	-	Transcriptional regulator
NHFCAKPK_00911	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHFCAKPK_00912	7.1e-78	phnA	-	-	P	ko:K06193	ko01120,map01120	ko00000	Alkylphosphonate utilization operon protein PhnA
NHFCAKPK_00913	1.67e-135	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_00914	2.06e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHFCAKPK_00915	1.24e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NHFCAKPK_00916	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHFCAKPK_00917	2.8e-64	-	-	-	-	-	-	-	-
NHFCAKPK_00918	9.86e-59	-	-	-	-	-	-	-	-
NHFCAKPK_00919	2.84e-240	adhP	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NHFCAKPK_00920	7.83e-127	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NHFCAKPK_00921	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NHFCAKPK_00922	1.5e-161	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
NHFCAKPK_00923	3.35e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHFCAKPK_00924	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHFCAKPK_00925	2.21e-110	-	-	-	-	ko:K16788	-	ko00000,ko02000	-
NHFCAKPK_00926	1.11e-117	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
NHFCAKPK_00927	2.14e-164	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
NHFCAKPK_00928	1.4e-201	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHFCAKPK_00929	6.71e-173	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHFCAKPK_00930	5.89e-205	-	-	-	GK	-	-	-	ROK family
NHFCAKPK_00931	1.06e-198	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
NHFCAKPK_00932	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHFCAKPK_00933	6.84e-188	-	-	-	S	-	-	-	TraX protein
NHFCAKPK_00934	6.64e-154	yycF1	-	-	T	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHFCAKPK_00935	1.54e-308	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NHFCAKPK_00936	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NHFCAKPK_00937	3.04e-282	XK27_05470	-	-	E	-	-	-	Methionine synthase
NHFCAKPK_00938	2.02e-91	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NHFCAKPK_00939	7.34e-56	-	-	-	P	-	-	-	Rhodanese-like protein
NHFCAKPK_00940	5.4e-175	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Acetoin reductase
NHFCAKPK_00942	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHFCAKPK_00945	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NHFCAKPK_00946	7.74e-172	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
NHFCAKPK_00947	6.66e-88	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NHFCAKPK_00948	6.92e-184	-	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	epimerase
NHFCAKPK_00949	2.09e-157	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_00950	0.0	proWX	-	-	P	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NHFCAKPK_00951	2.86e-176	-	-	-	S	-	-	-	Phenazine biosynthesis protein
NHFCAKPK_00952	1.23e-126	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
NHFCAKPK_00953	3.58e-169	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
NHFCAKPK_00954	1.63e-200	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
NHFCAKPK_00955	2.82e-192	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NHFCAKPK_00956	5.77e-81	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NHFCAKPK_00957	7.07e-87	-	-	-	K	-	-	-	Transcriptional regulator
NHFCAKPK_00958	8.26e-226	-	-	-	C	-	-	-	nadph quinone reductase
NHFCAKPK_00959	1.15e-82	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NHFCAKPK_00960	2.59e-89	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NHFCAKPK_00961	4.02e-186	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHFCAKPK_00962	1.92e-208	-	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NHFCAKPK_00963	2.86e-50	-	-	-	-	-	-	-	-
NHFCAKPK_00964	2.56e-75	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
NHFCAKPK_00965	1.53e-127	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
NHFCAKPK_00966	1.38e-199	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
NHFCAKPK_00967	9.59e-247	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
NHFCAKPK_00968	3.06e-238	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
NHFCAKPK_00969	9.68e-86	copY	-	-	K	-	-	-	Copper transport repressor, CopY TcrY family
NHFCAKPK_00970	3.75e-86	-	-	-	S	-	-	-	cog cog4633
NHFCAKPK_00971	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NHFCAKPK_00972	4.49e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
NHFCAKPK_00973	1.62e-141	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
NHFCAKPK_00974	0.0	-	-	-	V	-	-	-	Type III restriction enzyme, res subunit
NHFCAKPK_00975	5.17e-223	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
NHFCAKPK_00976	5.85e-294	dinF	-	-	V	-	-	-	Mate efflux family protein
NHFCAKPK_00977	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHFCAKPK_00978	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
NHFCAKPK_00979	1.77e-170	-	-	-	S	-	-	-	TraX protein
NHFCAKPK_00980	2.78e-121	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
NHFCAKPK_00981	1.33e-186	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NHFCAKPK_00982	5.16e-221	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHFCAKPK_00983	3.26e-160	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NHFCAKPK_00984	3.05e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHFCAKPK_00985	1.41e-306	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
NHFCAKPK_00986	7.99e-191	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NHFCAKPK_00987	4.41e-103	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_00988	0.0	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NHFCAKPK_00989	1.88e-216	bglC	-	-	K	-	-	-	Transcriptional regulator
NHFCAKPK_00990	3.28e-312	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NHFCAKPK_00991	1.12e-303	agcS	-	-	E	ko:K03310	-	ko00000	(Alanine) symporter
NHFCAKPK_00992	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NHFCAKPK_00993	4.02e-305	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
NHFCAKPK_00994	9.02e-177	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NHFCAKPK_00995	4.08e-112	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NHFCAKPK_00996	1.15e-143	hsdS2	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
NHFCAKPK_00997	1.76e-47	M1-755	-	-	P	ko:K09155	-	ko00000	Hemerythrin HHE cation binding domain protein
NHFCAKPK_00998	3.25e-308	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
NHFCAKPK_00999	4.3e-188	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHFCAKPK_01000	1.8e-218	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NHFCAKPK_01001	3.58e-93	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHFCAKPK_01002	8.42e-60	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NHFCAKPK_01003	3.81e-183	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
NHFCAKPK_01004	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
NHFCAKPK_01005	9.4e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	phosphate
NHFCAKPK_01006	3.8e-200	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NHFCAKPK_01007	1.24e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate transport system permease
NHFCAKPK_01008	4.33e-192	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHFCAKPK_01009	2.05e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHFCAKPK_01010	1.33e-148	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NHFCAKPK_01011	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
NHFCAKPK_01012	1.78e-246	xerS	-	-	D	ko:K04763	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NHFCAKPK_01013	9.64e-107	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHFCAKPK_01014	2.94e-31	-	-	-	-	-	-	-	-
NHFCAKPK_01015	5.95e-101	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NHFCAKPK_01016	4.88e-236	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NHFCAKPK_01018	1.5e-115	-	-	-	L	ko:K07491	-	ko00000	COG1943 Transposase and inactivated derivatives
NHFCAKPK_01019	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NHFCAKPK_01020	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
NHFCAKPK_01021	3.73e-221	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NHFCAKPK_01022	6.81e-291	malX	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NHFCAKPK_01023	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_01024	2.6e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_01025	4.77e-270	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHFCAKPK_01026	6.58e-32	tatA	-	-	U	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein secretion
NHFCAKPK_01027	1.31e-160	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NHFCAKPK_01028	0.0	ywbL	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
NHFCAKPK_01029	3.38e-293	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	peroxidase
NHFCAKPK_01030	7.33e-191	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
NHFCAKPK_01031	0.0	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
NHFCAKPK_01032	0.0	amiA	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-Acetylmuramoyl-L-alanine amidase
NHFCAKPK_01033	0.0	-	3.5.1.28	-	S	ko:K01448,ko:K02395,ko:K21471	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036	dextransucrase activity
NHFCAKPK_01034	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NHFCAKPK_01035	9.21e-281	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHFCAKPK_01036	1.14e-231	acoB	1.2.4.1	-	C	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHFCAKPK_01037	1.19e-233	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NHFCAKPK_01038	1.36e-259	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHFCAKPK_01039	2.26e-287	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
NHFCAKPK_01040	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHFCAKPK_01041	5.94e-300	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHFCAKPK_01042	4.01e-154	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHFCAKPK_01043	4.78e-271	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHFCAKPK_01044	1.44e-311	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
NHFCAKPK_01045	4.57e-229	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
NHFCAKPK_01046	3.82e-194	-	-	-	S	-	-	-	Phospholipase, patatin family
NHFCAKPK_01047	2.67e-126	-	-	-	E	-	-	-	Lysophospholipase L1 and related esterases
NHFCAKPK_01048	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	unusual protein kinase
NHFCAKPK_01049	3.9e-51	-	-	-	S	-	-	-	granule-associated protein
NHFCAKPK_01050	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NHFCAKPK_01051	6.25e-250	XK27_12525	-	-	S	-	-	-	hmm pf01594
NHFCAKPK_01052	1.12e-137	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NHFCAKPK_01053	4.53e-139	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NHFCAKPK_01054	1.16e-140	XK27_06100	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NHFCAKPK_01055	1.23e-189	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NHFCAKPK_01057	8.49e-243	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NHFCAKPK_01058	5.5e-238	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
NHFCAKPK_01059	8.61e-276	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NHFCAKPK_01060	6.21e-304	wzx	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NHFCAKPK_01061	1.5e-223	-	-	-	-	-	-	-	-
NHFCAKPK_01062	7.47e-205	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NHFCAKPK_01063	3.18e-214	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
NHFCAKPK_01064	3.39e-207	-	-	-	-	-	-	-	-
NHFCAKPK_01065	5.3e-157	-	-	-	M	-	-	-	Domain of unknown function (DUF1919)
NHFCAKPK_01066	3.48e-267	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
NHFCAKPK_01067	2.33e-283	rgpAc	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	group 1 family protein
NHFCAKPK_01068	0.0	cpsE	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NHFCAKPK_01069	4.49e-154	cpsD	-	-	D	-	-	-	COG0489 ATPases involved in chromosome partitioning
NHFCAKPK_01070	8.78e-144	capA	-	-	M	-	-	-	biosynthesis protein
NHFCAKPK_01071	2.04e-169	cpsB	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	Capsular polysaccharide biosynthesis protein
NHFCAKPK_01072	1.51e-314	cps4A	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NHFCAKPK_01073	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine nucleoside phosphorylase
NHFCAKPK_01074	2.31e-172	gat	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine amidotransferase
NHFCAKPK_01075	1.13e-226	-	-	-	P	-	-	-	Chloride transporter, ClC family
NHFCAKPK_01076	1.97e-189	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NHFCAKPK_01077	2.55e-112	-	-	-	S	-	-	-	Protein of unknown function (DUF1697)
NHFCAKPK_01078	4.3e-297	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NHFCAKPK_01079	8e-154	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NHFCAKPK_01080	0.0	-	-	-	V	ko:K13732	ko05100,map05100	ko00000,ko00001	Glucan-binding protein C
NHFCAKPK_01081	2.26e-309	-	-	-	V	-	-	-	Glucan-binding protein C
NHFCAKPK_01082	5.79e-138	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
NHFCAKPK_01083	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Dipeptidase
NHFCAKPK_01084	1.38e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
NHFCAKPK_01085	5.06e-115	yybC	-	-	-	-	-	-	-
NHFCAKPK_01086	1.2e-97	XK27_03610	-	-	K	-	-	-	Gnat family
NHFCAKPK_01087	1.82e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHFCAKPK_01088	2.36e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NHFCAKPK_01089	1.1e-115	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHFCAKPK_01090	3.39e-155	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NHFCAKPK_01091	3.71e-29	-	-	-	M	-	-	-	LysM domain
NHFCAKPK_01092	2.35e-112	ebsA	-	-	S	-	-	-	Family of unknown function (DUF5322)
NHFCAKPK_01093	6.3e-292	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NHFCAKPK_01094	0.0	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
NHFCAKPK_01095	1.8e-123	sipC	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NHFCAKPK_01096	1.7e-281	XK27_05225	-	-	G	-	-	-	COG0457 FOG TPR repeat
NHFCAKPK_01097	3e-232	XK27_05220	-	-	S	-	-	-	permease
NHFCAKPK_01098	6.84e-118	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NTP pyrophosphohydrolases including oxidative damage repair enzymes
NHFCAKPK_01099	8.45e-211	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NHFCAKPK_01100	7.31e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
NHFCAKPK_01101	3.1e-231	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHFCAKPK_01102	4.75e-267	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NHFCAKPK_01103	4.97e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NHFCAKPK_01104	2.03e-167	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NHFCAKPK_01105	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	cation transport ATPase
NHFCAKPK_01106	1.39e-88	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
NHFCAKPK_01107	1.86e-170	-	-	-	F	-	-	-	Phosphorylase superfamily
NHFCAKPK_01108	8.28e-177	XK27_00115	-	-	K	-	-	-	Acetyltransferase GNAT family
NHFCAKPK_01109	1.89e-187	XK27_00835	-	-	S	-	-	-	hydrolases of the HAD superfamily
NHFCAKPK_01110	5.57e-289	femX	2.3.2.10, 2.3.2.16	-	V	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
NHFCAKPK_01111	4.46e-74	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
NHFCAKPK_01112	1.46e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Metal-dependent hydrolases of the beta-lactamase superfamily I
NHFCAKPK_01113	1.23e-311	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHFCAKPK_01114	4.13e-165	yycF	-	-	KT	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHFCAKPK_01115	4.89e-27	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHFCAKPK_01116	2.86e-128	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHFCAKPK_01117	8.63e-188	peb1A	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
NHFCAKPK_01118	1.68e-158	XK27_07620	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_01119	5.84e-142	-	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
NHFCAKPK_01120	1.1e-179	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHFCAKPK_01121	2.76e-184	peb1A	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
NHFCAKPK_01122	8.31e-159	XK27_07620	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_01123	5.84e-142	-	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
NHFCAKPK_01124	1.05e-196	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
NHFCAKPK_01125	2.03e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
NHFCAKPK_01126	1.62e-293	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHFCAKPK_01128	5.8e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NHFCAKPK_01129	8.83e-167	-	-	-	G	-	-	-	Domain of unknown function (DUF4832)
NHFCAKPK_01130	3.23e-108	-	-	-	S	-	-	-	membrane
NHFCAKPK_01131	8.51e-123	-	-	-	P	-	-	-	VTC domain
NHFCAKPK_01132	1.47e-280	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
NHFCAKPK_01133	1.72e-239	-	-	-	M	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
NHFCAKPK_01134	0.0	-	2.4.1.52	GT4	M	ko:K00712,ko:K21011	ko02025,map02025	ko00000,ko00001,ko01000,ko01003	Domain of unknown function (DUF3492)
NHFCAKPK_01135	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
NHFCAKPK_01136	2.78e-184	-	-	-	-	-	-	-	-
NHFCAKPK_01137	0.0	-	5.1.3.2	-	GM	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	ko00000,ko00001,ko00002,ko01000	Psort location CytoplasmicMembrane, score
NHFCAKPK_01138	4.94e-268	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHFCAKPK_01139	7.63e-220	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHFCAKPK_01140	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHFCAKPK_01141	1.71e-111	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
NHFCAKPK_01142	5.45e-204	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHFCAKPK_01143	9.42e-28	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
NHFCAKPK_01146	2.33e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHFCAKPK_01147	2.02e-270	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter ClC family
NHFCAKPK_01148	1.05e-54	pheA	1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5	-	E	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
NHFCAKPK_01149	0.0	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter, ClC family
NHFCAKPK_01150	2.45e-98	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NHFCAKPK_01151	2.52e-26	XK27_08880	-	-	-	-	-	-	-
NHFCAKPK_01152	1.8e-161	XK27_08875	-	-	O	-	-	-	Zinc-dependent metalloprotease
NHFCAKPK_01153	4.17e-191	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Esterase
NHFCAKPK_01154	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHFCAKPK_01155	2.2e-173	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_01156	3.22e-189	XK27_08840	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHFCAKPK_01157	3.39e-229	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
NHFCAKPK_01159	0.0	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHFCAKPK_01160	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NHFCAKPK_01161	3.31e-239	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NHFCAKPK_01162	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NHFCAKPK_01163	6.51e-145	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHFCAKPK_01164	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHFCAKPK_01165	7.84e-241	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NHFCAKPK_01166	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NHFCAKPK_01167	8.04e-70	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHFCAKPK_01168	1.33e-91	-	-	-	S	ko:K06893	-	ko00000	SnoaL-like polyketide cyclase
NHFCAKPK_01169	6.88e-71	hxlR	-	-	K	-	-	-	HxlR-like helix-turn-helix
NHFCAKPK_01170	2.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NHFCAKPK_01171	2.05e-228	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
NHFCAKPK_01173	3.1e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHFCAKPK_01174	3.07e-122	ypmS	-	-	S	-	-	-	Protein conserved in bacteria
NHFCAKPK_01175	3.99e-200	XK27_03630	-	-	E	-	-	-	COG2755 Lysophospholipase L1 and related esterases
NHFCAKPK_01176	2.1e-185	WQ51_01275	-	-	S	-	-	-	DegV family
NHFCAKPK_01177	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NHFCAKPK_01178	1.26e-96	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NHFCAKPK_01179	1.89e-190	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NHFCAKPK_01180	1.06e-199	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NHFCAKPK_01181	2.44e-40	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHFCAKPK_01182	8.49e-295	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHFCAKPK_01184	7.2e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHFCAKPK_01185	1.82e-162	dnaD	-	-	-	ko:K02086	-	ko00000	-
NHFCAKPK_01186	1.63e-231	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHFCAKPK_01187	1.25e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHFCAKPK_01188	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease recj
NHFCAKPK_01189	7.01e-85	GnaT	2.5.1.16	-	K	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferase
NHFCAKPK_01190	8.21e-28	-	-	-	Q	-	-	-	Methyltransferase domain
NHFCAKPK_01191	4.11e-175	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHFCAKPK_01192	3.64e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHFCAKPK_01193	1.14e-142	XK27_05445	-	-	G	-	-	-	UDPglucose--hexose-1-phosphate uridylyltransferase
NHFCAKPK_01194	1.96e-309	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHFCAKPK_01195	2.35e-294	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NHFCAKPK_01196	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
NHFCAKPK_01197	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
NHFCAKPK_01198	0.0	-	2.4.1.5	GH13	M	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	KxYKxGKxW signal domain protein
NHFCAKPK_01199	1.75e-230	-	-	-	M	-	-	-	glycosyl transferase family 2
NHFCAKPK_01200	1.15e-168	-	-	-	S	-	-	-	Carbohydrate-binding domain-containing protein Cthe_2159
NHFCAKPK_01201	1.45e-186	-	-	-	P	-	-	-	molecular chaperone
NHFCAKPK_01202	3.1e-134	XK27_05505	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHFCAKPK_01204	1.27e-66	hisE	3.5.4.19, 3.6.1.31, 5.3.1.16	-	E	ko:K01523,ko:K01814,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
NHFCAKPK_01205	4.95e-79	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NHFCAKPK_01206	2.29e-175	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NHFCAKPK_01207	1.96e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NHFCAKPK_01208	4.72e-141	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NHFCAKPK_01209	2.36e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
NHFCAKPK_01210	1.45e-298	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NHFCAKPK_01211	3.42e-150	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NHFCAKPK_01212	1.76e-232	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NHFCAKPK_01213	6.24e-245	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NHFCAKPK_01214	7.41e-80	XK27_08085	-	-	-	-	-	-	-
NHFCAKPK_01215	1.53e-196	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
NHFCAKPK_01216	9.75e-174	hisJ	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
NHFCAKPK_01217	1.51e-152	-	-	-	S	-	-	-	tigr01906
NHFCAKPK_01218	7.4e-179	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHFCAKPK_01219	1.45e-180	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NHFCAKPK_01220	2.47e-272	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
NHFCAKPK_01223	1.57e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NHFCAKPK_01224	9.6e-143	rmlC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NHFCAKPK_01225	7.83e-206	rfbA	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NHFCAKPK_01226	0.0	-	-	-	S	-	-	-	phospholipase Carboxylesterase
NHFCAKPK_01227	4.43e-251	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	oxidoreductase
NHFCAKPK_01228	2.44e-182	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
NHFCAKPK_01229	1.5e-185	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHFCAKPK_01230	3.12e-152	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NHFCAKPK_01231	7.45e-86	mesH	-	-	S	-	-	-	GtrA-like protein
NHFCAKPK_01232	9.24e-317	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHFCAKPK_01233	1.23e-209	ybbR	-	-	S	-	-	-	Protein conserved in bacteria
NHFCAKPK_01234	9.63e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHFCAKPK_01235	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain protein
NHFCAKPK_01236	5.93e-192	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
NHFCAKPK_01237	0.0	mprF	2.3.2.3	-	J	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHFCAKPK_01238	1.82e-170	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha beta hydrolase
NHFCAKPK_01239	7.55e-53	-	-	-	S	-	-	-	yiaA/B two helix domain
NHFCAKPK_01240	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	abc transporter atp-binding protein
NHFCAKPK_01241	5.27e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NHFCAKPK_01242	4.16e-239	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
NHFCAKPK_01243	8.51e-289	XK27_05680	-	-	M	-	-	-	carbamoylphosphate synthase large subunit
NHFCAKPK_01244	4.54e-197	XK27_05675	-	-	S	-	-	-	Esterase
NHFCAKPK_01245	7.56e-206	XK27_05670	-	-	S	ko:K07017	-	ko00000	Putative esterase
NHFCAKPK_01246	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NHFCAKPK_01247	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHFCAKPK_01248	2.72e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein Hpr
NHFCAKPK_01249	1.46e-282	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate dehydrogenase
NHFCAKPK_01250	2.02e-269	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
NHFCAKPK_01251	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NHFCAKPK_01252	3.36e-46	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NHFCAKPK_01253	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHFCAKPK_01254	4.51e-236	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHFCAKPK_01255	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHFCAKPK_01256	2.89e-193	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
NHFCAKPK_01257	5.43e-186	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
NHFCAKPK_01258	1.13e-40	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
NHFCAKPK_01259	1.1e-117	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	cell septum assembly
NHFCAKPK_01260	8.63e-154	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NHFCAKPK_01261	1.2e-299	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHFCAKPK_01262	5.77e-291	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHFCAKPK_01263	2.01e-190	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHFCAKPK_01264	5.01e-254	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHFCAKPK_01265	4.62e-316	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHFCAKPK_01266	3.66e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3165)
NHFCAKPK_01267	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NHFCAKPK_01268	1.88e-225	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NHFCAKPK_01269	4.13e-38	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
NHFCAKPK_01270	8.12e-103	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NHFCAKPK_01271	2.93e-114	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NHFCAKPK_01272	1.83e-130	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
NHFCAKPK_01273	5.97e-239	-	-	-	V	-	-	-	D-alanyl-D-alanine carboxypeptidase
NHFCAKPK_01274	1.85e-142	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
NHFCAKPK_01275	1.33e-233	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NHFCAKPK_01276	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NHFCAKPK_01277	7.65e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
NHFCAKPK_01278	2.88e-95	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
NHFCAKPK_01279	6.79e-163	sitB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K10830,ko:K11706,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NHFCAKPK_01280	4.11e-171	mtsC	-	-	P	ko:K11705,ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type Mn2 Zn2 transport systems, permease components
NHFCAKPK_01281	3.23e-219	psaA	-	-	P	ko:K11704,ko:K19971,ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NHFCAKPK_01282	3.97e-144	sirR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
NHFCAKPK_01283	2.32e-187	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NHFCAKPK_01284	3.61e-119	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NHFCAKPK_01285	4.67e-234	spd	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
NHFCAKPK_01286	0.0	-	-	-	M	-	-	-	Right handed beta helix region
NHFCAKPK_01287	2.85e-187	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
NHFCAKPK_01288	6.12e-235	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NHFCAKPK_01289	9.92e-58	-	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
NHFCAKPK_01290	2.46e-171	sdh	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHFCAKPK_01291	3.75e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
NHFCAKPK_01292	2.83e-145	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHFCAKPK_01293	2.32e-198	hmpP2	-	-	G	-	-	-	hydrolase
NHFCAKPK_01294	9.26e-35	-	-	-	P	-	-	-	Hemerythrin HHE cation binding domain protein
NHFCAKPK_01295	1.93e-191	-	3.5.1.28	-	M	ko:K01447,ko:K07273	-	ko00000,ko01000	Glycosyl hydrolase, family 25
NHFCAKPK_01296	8.68e-106	-	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHFCAKPK_01297	1.7e-148	pgm	-	-	G	-	-	-	Phosphoglycerate mutase
NHFCAKPK_01299	3.26e-224	-	-	-	S	ko:K07025	-	ko00000	hydrolase
NHFCAKPK_01300	1.73e-36	-	-	-	-	-	-	-	-
NHFCAKPK_01301	5.87e-199	-	-	-	M	-	-	-	LysM domain
NHFCAKPK_01302	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NHFCAKPK_01304	0.0	-	-	-	L	-	-	-	helicase
NHFCAKPK_01305	7.16e-84	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
NHFCAKPK_01306	4.16e-18	-	-	-	-	-	-	-	-
NHFCAKPK_01307	9.35e-295	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NHFCAKPK_01308	2.97e-45	XK27_12190	-	-	S	-	-	-	protein conserved in bacteria
NHFCAKPK_01310	4.42e-112	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin synthase
NHFCAKPK_01311	0.0	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
NHFCAKPK_01312	1.75e-228	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
NHFCAKPK_01314	1.86e-88	ytxH	-	-	S	-	-	-	General stress protein
NHFCAKPK_01315	9.98e-28	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NHFCAKPK_01316	8.04e-186	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHFCAKPK_01317	1.78e-212	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHFCAKPK_01318	1.02e-55	WQ51_05770	-	-	KT	-	-	-	PspC domain
NHFCAKPK_01319	0.0	tex	-	-	K	ko:K06959	-	ko00000	Transcriptional accessory protein
NHFCAKPK_01321	1.14e-199	XK27_03015	-	-	S	ko:K07089	-	ko00000	permease
NHFCAKPK_01322	4.15e-192	XK27_03010	-	-	S	ko:K08986	-	ko00000	TIGR03943 family
NHFCAKPK_01323	2.27e-215	-	-	-	S	-	-	-	CRISPR-associated protein Csn2 subfamily St
NHFCAKPK_01324	8.44e-71	-	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHFCAKPK_01325	1.32e-220	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHFCAKPK_01326	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NHFCAKPK_01327	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	Sulfate permease and related transporters (MFS superfamily)
NHFCAKPK_01328	1.39e-134	-	-	-	-	-	-	-	-
NHFCAKPK_01329	7.78e-150	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NHFCAKPK_01330	1.97e-113	-	-	-	S	-	-	-	CAAX protease self-immunity
NHFCAKPK_01331	1.25e-66	-	-	-	-	-	-	-	-
NHFCAKPK_01333	2.47e-85	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
NHFCAKPK_01334	3.25e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
NHFCAKPK_01335	2.89e-28	-	-	-	M	-	-	-	Bacterial lipoprotein
NHFCAKPK_01337	5.28e-159	-	-	-	V	-	-	-	CAAX protease self-immunity
NHFCAKPK_01338	2.67e-63	-	-	-	-	-	-	-	-
NHFCAKPK_01339	4.02e-181	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHFCAKPK_01340	2.63e-222	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	dehydrogenase E1 component
NHFCAKPK_01341	5.03e-211	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	Acetoin dehydrogenase E1 component subunit alpha
NHFCAKPK_01342	1.77e-214	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NHFCAKPK_01343	6.53e-32	-	-	-	K	-	-	-	CsbD-like
NHFCAKPK_01344	1.09e-42	ytgB	-	-	S	-	-	-	Membrane
NHFCAKPK_01345	2.87e-218	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
NHFCAKPK_01346	2.81e-201	yegS	-	-	I	-	-	-	Diacylglycerol kinase
NHFCAKPK_01347	2.77e-161	-	-	-	S	-	-	-	Putative esterase
NHFCAKPK_01348	1.74e-229	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NHFCAKPK_01349	1.38e-171	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NHFCAKPK_01350	1.94e-215	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHFCAKPK_01351	6e-147	-	-	-	V	-	-	-	CAAX protease self-immunity
NHFCAKPK_01352	3.82e-192	-	-	-	S	-	-	-	Domain of unknown function (DUF4300)
NHFCAKPK_01353	5.4e-118	tetR	-	-	K	-	-	-	transcriptional regulator
NHFCAKPK_01354	0.0	-	-	-	P	-	-	-	Major facilitator superfamily
NHFCAKPK_01355	1.76e-18	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
NHFCAKPK_01357	7.4e-138	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
NHFCAKPK_01358	2.42e-165	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family
NHFCAKPK_01359	8.2e-127	yagB	-	-	F	ko:K06950	-	ko00000	HD superfamily hydrolase
NHFCAKPK_01360	1.91e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHFCAKPK_01361	3.39e-191	ChZ00x2	-	-	S	-	-	-	EDD domain protein, DegV family
NHFCAKPK_01362	9.37e-258	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	transporter
NHFCAKPK_01363	2.78e-168	-	-	-	S	-	-	-	Domain of unknown function (DUF4336)
NHFCAKPK_01364	4.55e-169	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHFCAKPK_01365	1.04e-17	-	-	-	-	-	-	-	-
NHFCAKPK_01366	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
NHFCAKPK_01367	6.55e-167	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_01368	1.37e-148	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation, permease component
NHFCAKPK_01369	3.57e-144	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHFCAKPK_01370	8.23e-126	-	-	-	-	-	-	-	-
NHFCAKPK_01371	5.07e-125	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NHFCAKPK_01372	2.76e-163	lyrA	-	-	S	-	-	-	CAAX amino terminal protease family protein
NHFCAKPK_01373	1.32e-97	-	-	-	J	-	-	-	Acetyltransferase GNAT family
NHFCAKPK_01374	5.43e-181	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHFCAKPK_01376	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
NHFCAKPK_01377	4.62e-81	-	-	-	K	ko:K21903	-	ko00000,ko03000	Transcriptional regulator
NHFCAKPK_01378	5.1e-69	XK27_05385	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
NHFCAKPK_01379	6.36e-98	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
NHFCAKPK_01380	8.46e-50	uvrX	2.7.7.7	-	L	ko:K02346,ko:K03502,ko:K14161	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHFCAKPK_01381	4.1e-73	-	-	-	-	-	-	-	-
NHFCAKPK_01382	7.32e-79	-	-	-	-	-	-	-	-
NHFCAKPK_01383	8.78e-67	-	-	-	-	-	-	-	-
NHFCAKPK_01384	0.0	-	-	-	S	-	-	-	ABC transporter
NHFCAKPK_01385	1.55e-275	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
NHFCAKPK_01386	3.6e-31	-	-	-	-	-	-	-	-
NHFCAKPK_01387	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHFCAKPK_01388	1.28e-126	mip	-	-	S	-	-	-	hydroperoxide reductase activity
NHFCAKPK_01389	3.52e-253	-	-	-	I	-	-	-	acyl-CoA dehydrogenase
NHFCAKPK_01390	3.2e-196	ydiA	-	-	P	ko:K03304,ko:K11041	ko05150,map05150	ko00000,ko00001,ko02000,ko02042	C4-dicarboxylate transporter malic acid transport protein
NHFCAKPK_01391	0.0	msrR	-	-	K	-	-	-	Transcriptional regulator
NHFCAKPK_01392	9.85e-197	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
NHFCAKPK_01393	7.63e-112	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NHFCAKPK_01394	1.33e-294	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NHFCAKPK_01395	1.72e-218	hicD2	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NHFCAKPK_01396	1.73e-70	XK26_04240	-	-	S	-	-	-	Belongs to the UPF0342 family
NHFCAKPK_01397	1.45e-259	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
NHFCAKPK_01398	1.5e-278	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NHFCAKPK_01399	1.69e-256	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NHFCAKPK_01400	3.28e-196	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NHFCAKPK_01401	1.67e-150	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NHFCAKPK_01402	3.14e-275	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
NHFCAKPK_01403	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
NHFCAKPK_01404	4.48e-34	WQ51_00785	-	-	-	-	-	-	-
NHFCAKPK_01405	6.13e-315	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHFCAKPK_01406	2.24e-96	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NHFCAKPK_01407	5.51e-245	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NHFCAKPK_01408	1.09e-252	XK27_07735	-	-	S	-	-	-	YjbR
NHFCAKPK_01409	4.5e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	Catabolite control protein A
NHFCAKPK_01410	6.99e-245	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
NHFCAKPK_01411	1.05e-59	-	-	-	L	-	-	-	transposase activity
NHFCAKPK_01412	3.85e-194	-	-	-	L	-	-	-	Integrase core domain
NHFCAKPK_01413	1.17e-84	yugI	-	-	J	ko:K07570	-	ko00000	RNA binding protein, contains ribosomal protein S1 domain
NHFCAKPK_01414	0.0	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHFCAKPK_01415	1.98e-105	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NHFCAKPK_01416	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHFCAKPK_01417	1.06e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
NHFCAKPK_01418	1.77e-282	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	Major Facilitator
NHFCAKPK_01419	3.33e-134	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHFCAKPK_01420	3.31e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHFCAKPK_01421	1.65e-212	era	-	-	M	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHFCAKPK_01422	8.52e-86	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NHFCAKPK_01423	3.1e-112	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHFCAKPK_01424	2.46e-186	licT	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
NHFCAKPK_01425	1.85e-136	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHFCAKPK_01426	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
NHFCAKPK_01427	7.33e-185	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHFCAKPK_01428	2.73e-198	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHFCAKPK_01429	1.34e-186	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NHFCAKPK_01430	1.2e-12	-	-	-	-	-	-	-	-
NHFCAKPK_01431	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NHFCAKPK_01432	6.08e-102	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain protein
NHFCAKPK_01433	7.38e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHFCAKPK_01434	1.27e-150	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHFCAKPK_01435	3.31e-47	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
NHFCAKPK_01436	1.51e-233	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHFCAKPK_01437	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NHFCAKPK_01438	1.11e-110	XK27_09440	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
NHFCAKPK_01439	2.23e-65	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
NHFCAKPK_01440	1.04e-221	-	-	-	S	-	-	-	oxidoreductase
NHFCAKPK_01441	1.22e-291	murN	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	FemAB family
NHFCAKPK_01442	7.94e-150	-	-	-	M	-	-	-	Pfam SNARE associated Golgi protein
NHFCAKPK_01443	5.27e-140	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
NHFCAKPK_01446	9.51e-268	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein S1
NHFCAKPK_01449	9.87e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
NHFCAKPK_01450	2.04e-254	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NHFCAKPK_01451	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHFCAKPK_01454	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHFCAKPK_01455	1.09e-140	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHFCAKPK_01456	4.35e-19	-	-	-	L	-	-	-	Helix-hairpin-helix DNA-binding motif class 1
NHFCAKPK_01457	3.14e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF1912)
NHFCAKPK_01458	4.42e-221	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	Homocysteine
NHFCAKPK_01459	0.0	lysP	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NHFCAKPK_01460	9.58e-144	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NHFCAKPK_01461	8.89e-288	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHFCAKPK_01462	2.97e-30	-	-	-	-	-	-	-	-
NHFCAKPK_01463	2.6e-115	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHFCAKPK_01464	2.01e-211	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHFCAKPK_01465	3.63e-270	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	synthase
NHFCAKPK_01466	2.14e-280	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
NHFCAKPK_01467	1.08e-102	-	-	-	K	-	-	-	hmm pf08876
NHFCAKPK_01468	2.89e-151	hly-III	-	-	K	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
NHFCAKPK_01469	1.64e-39	pspC	-	-	KT	-	-	-	PspC domain protein
NHFCAKPK_01470	3.52e-252	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
NHFCAKPK_01471	4.67e-204	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHFCAKPK_01472	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHFCAKPK_01474	0.0	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NHFCAKPK_01475	1.21e-242	dgs	2.4.1.208	GT4	M	ko:K13677	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NHFCAKPK_01476	0.0	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
NHFCAKPK_01477	1.42e-149	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHFCAKPK_01478	8.88e-43	-	-	-	-	-	-	-	-
NHFCAKPK_01479	4.8e-122	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	AdP-ribose pyrophosphatase
NHFCAKPK_01480	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHFCAKPK_01481	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
NHFCAKPK_01482	9.8e-234	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NHFCAKPK_01483	1.96e-211	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
NHFCAKPK_01484	1.48e-218	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
NHFCAKPK_01485	1.65e-188	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
NHFCAKPK_01486	8.96e-134	-	-	-	J	ko:K09962	-	ko00000	protein conserved in bacteria
NHFCAKPK_01487	1.39e-313	merA	-	-	C	-	-	-	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHFCAKPK_01488	3.24e-163	-	-	-	E	-	-	-	Alpha beta hydrolase
NHFCAKPK_01490	5.21e-254	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
NHFCAKPK_01491	3.04e-279	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NHFCAKPK_01492	1.06e-183	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NHFCAKPK_01493	1.87e-148	-	-	-	S	-	-	-	VIT family
NHFCAKPK_01494	6.04e-173	-	-	-	F	-	-	-	Phosphorylase superfamily
NHFCAKPK_01495	9.42e-27	-	-	-	-	-	-	-	-
NHFCAKPK_01496	3.25e-40	XK27_00085	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
NHFCAKPK_01497	3.36e-251	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
NHFCAKPK_01498	9.92e-155	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NHFCAKPK_01499	4.18e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NHFCAKPK_01500	1.14e-167	rr02	-	-	KT	-	-	-	response regulator
NHFCAKPK_01501	2.27e-288	hk02	-	-	T	-	-	-	signal transduction protein with a C-terminal ATPase domain
NHFCAKPK_01502	8.97e-159	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHFCAKPK_01503	3.53e-254	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NHFCAKPK_01504	0.0	lmrA	-	-	V	ko:K06147,ko:K18888	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_01505	0.0	msbA_1	-	-	V	ko:K18887	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_01506	5.17e-39	-	-	-	K	ko:K02051	-	ko00000,ko00002,ko02000	DNA-binding transcription factor activity
NHFCAKPK_01507	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
NHFCAKPK_01508	8.16e-139	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
NHFCAKPK_01509	4.43e-37	XK27_00530	-	-	M	-	-	-	CHAP domain protein
NHFCAKPK_01510	3.41e-30	-	-	-	S	ko:K19165	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
NHFCAKPK_01512	8.3e-171	-	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulator of the LytR AlgR family
NHFCAKPK_01513	1.23e-294	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NHFCAKPK_01516	6.49e-65	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHFCAKPK_01517	1.7e-101	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHFCAKPK_01518	2.28e-271	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	permease protein
NHFCAKPK_01519	7.96e-158	salX	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHFCAKPK_01520	7.29e-248	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHFCAKPK_01521	5.47e-160	-	-	-	J	-	-	-	Putative SAM-dependent methyltransferase
NHFCAKPK_01522	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase ammonia chain
NHFCAKPK_01523	1.53e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase glutamine chain
NHFCAKPK_01524	5.83e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NHFCAKPK_01525	1.16e-280	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	uracil Permease
NHFCAKPK_01526	5.91e-114	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHFCAKPK_01527	1.03e-207	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NHFCAKPK_01528	1.1e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHFCAKPK_01529	2.86e-214	lysR	-	-	K	-	-	-	transcriptional regulator (lysR family)
NHFCAKPK_01531	6.76e-58	-	-	-	-	-	-	-	-
NHFCAKPK_01532	9.3e-91	-	-	-	K	-	-	-	Helix-turn-helix
NHFCAKPK_01536	2.49e-179	ppiA	5.2.1.8	-	O	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHFCAKPK_01537	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHFCAKPK_01539	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	permease
NHFCAKPK_01540	2.87e-52	ynzC	-	-	S	-	-	-	UPF0291 protein
NHFCAKPK_01541	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NHFCAKPK_01542	1.23e-226	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NHFCAKPK_01543	1.25e-281	-	-	-	S	-	-	-	membrane
NHFCAKPK_01544	8.31e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NHFCAKPK_01545	0.0	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
NHFCAKPK_01546	4.72e-151	-	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
NHFCAKPK_01547	1.23e-97	-	-	-	S	-	-	-	Bacterial inner membrane protein
NHFCAKPK_01548	1.6e-181	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NHFCAKPK_01549	5.13e-137	mur1	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
NHFCAKPK_01550	1.24e-31	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter
NHFCAKPK_01551	9.87e-204	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHFCAKPK_01552	2e-73	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NHFCAKPK_01553	1.93e-175	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
NHFCAKPK_01554	2.15e-204	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	dna polymerase iii
NHFCAKPK_01555	4.66e-140	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHFCAKPK_01557	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NHFCAKPK_01558	7.68e-174	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHFCAKPK_01559	3.2e-285	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHFCAKPK_01560	5.84e-277	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NHFCAKPK_01561	1.24e-89	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NHFCAKPK_01562	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHFCAKPK_01563	9.08e-202	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHFCAKPK_01564	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHFCAKPK_01565	8.62e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHFCAKPK_01566	2.96e-85	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NHFCAKPK_01567	2.87e-156	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NHFCAKPK_01568	5.88e-23	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHFCAKPK_01569	0.0	-	-	-	S	-	-	-	AAA ATPase domain
NHFCAKPK_01570	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHFCAKPK_01571	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
NHFCAKPK_01572	5.21e-130	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHFCAKPK_01573	5.57e-135	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHFCAKPK_01574	1.38e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NHFCAKPK_01576	4.73e-189	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	Transporter
NHFCAKPK_01577	2.49e-196	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NHFCAKPK_01578	1.47e-303	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NHFCAKPK_01579	4.14e-198	icaB	-	-	G	-	-	-	deacetylase
NHFCAKPK_01580	4.68e-260	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
NHFCAKPK_01581	2.01e-161	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
NHFCAKPK_01582	2.6e-279	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHFCAKPK_01583	1.34e-234	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NHFCAKPK_01584	2.42e-282	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
NHFCAKPK_01585	1.88e-178	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NHFCAKPK_01586	0.0	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
NHFCAKPK_01588	0.0	-	-	-	NU	-	-	-	GBS Bsp-like repeat
NHFCAKPK_01589	1.51e-297	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NHFCAKPK_01590	1.43e-150	agrA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
NHFCAKPK_01591	3.12e-09	-	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	response regulator
NHFCAKPK_01592	0.0	-	-	-	M	-	-	-	GBS Bsp-like repeat
NHFCAKPK_01595	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHFCAKPK_01596	1.61e-112	XK27_03390	-	-	S	-	-	-	LURP-one-related
NHFCAKPK_01597	2.64e-236	prsA	3.1.3.16, 5.2.1.8	-	O	ko:K01802,ko:K03769,ko:K07533,ko:K20074	-	ko00000,ko01000,ko01009,ko03110	peptidyl-prolyl cis-trans isomerase activity
NHFCAKPK_01598	5.91e-155	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-Methyltransferase
NHFCAKPK_01599	2.37e-274	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NHFCAKPK_01600	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
NHFCAKPK_01601	6.97e-215	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NHFCAKPK_01602	0.0	-	-	-	S	-	-	-	Glucan-binding protein C
NHFCAKPK_01603	7.83e-132	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
NHFCAKPK_01604	2.49e-214	-	-	-	K	-	-	-	transcriptional regulator (lysR family)
NHFCAKPK_01605	2e-204	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
NHFCAKPK_01606	2.93e-224	-	-	-	V	ko:K19147	-	ko00000,ko02048	McrBC 5-methylcytosine restriction system component
NHFCAKPK_01607	2.52e-179	-	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	COG1401 GTPase subunit of restriction endonuclease
NHFCAKPK_01608	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHFCAKPK_01612	6.93e-239	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
NHFCAKPK_01613	2.53e-210	sip	-	-	M	-	-	-	LysM domain protein
NHFCAKPK_01614	2.72e-46	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NHFCAKPK_01615	1.11e-203	yitL	-	-	S	ko:K00243	-	ko00000	Protein conserved in bacteria
NHFCAKPK_01616	7.89e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHFCAKPK_01617	2.78e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NHFCAKPK_01618	1.94e-270	sptS	-	-	T	-	-	-	Histidine kinase
NHFCAKPK_01619	5.6e-149	dltr	-	-	T	-	-	-	response regulator
NHFCAKPK_01620	2.51e-143	-	2.7.6.5	-	S	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
NHFCAKPK_01621	7.17e-141	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NHFCAKPK_01622	0.0	lmrA2	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
NHFCAKPK_01623	0.0	lmrA1	-	-	V	ko:K02021,ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
NHFCAKPK_01624	1.12e-94	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NHFCAKPK_01625	7.84e-92	def_1	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NHFCAKPK_01626	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHFCAKPK_01627	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NHFCAKPK_01628	3.62e-269	nadR	-	-	H	-	-	-	adenylyltransferase
NHFCAKPK_01629	6e-167	-	-	-	F	-	-	-	AdP-ribose pyrophosphatase
NHFCAKPK_01630	4.4e-30	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NHFCAKPK_01631	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	abc transporter atp-binding protein
NHFCAKPK_01632	1.28e-276	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHFCAKPK_01633	2.58e-178	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHFCAKPK_01634	2.67e-188	-	-	-	S	-	-	-	EDD domain protein, DegV family
NHFCAKPK_01635	2.63e-82	WQ51_03320	-	-	S	-	-	-	cog cog4835
NHFCAKPK_01636	4.68e-169	ydaF_2	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NHFCAKPK_01637	1.55e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NHFCAKPK_01638	1.99e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NHFCAKPK_01639	6.25e-107	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
NHFCAKPK_01640	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NHFCAKPK_01641	0.0	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NHFCAKPK_01642	2.16e-283	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHFCAKPK_01643	3.9e-266	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NHFCAKPK_01644	1.96e-07	-	-	-	-	-	-	-	-
NHFCAKPK_01645	2.86e-287	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NHFCAKPK_01646	0.0	gor	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NHFCAKPK_01647	7.18e-45	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHFCAKPK_01648	4.26e-221	-	-	-	L	ko:K07482	-	ko00000	Integrase
NHFCAKPK_01649	0.0	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHFCAKPK_01650	1.12e-212	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NHFCAKPK_01651	3.75e-163	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
NHFCAKPK_01652	6.36e-290	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NHFCAKPK_01653	6.58e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHFCAKPK_01654	4.63e-177	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NHFCAKPK_01655	1.71e-204	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHFCAKPK_01656	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NHFCAKPK_01657	1.19e-93	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHFCAKPK_01658	1.89e-87	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHFCAKPK_01659	3.69e-297	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHFCAKPK_01660	3.92e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NHFCAKPK_01661	1.51e-207	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
NHFCAKPK_01662	5.35e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	2-Nitropropane dioxygenase
NHFCAKPK_01663	2.12e-40	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHFCAKPK_01664	5.17e-222	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHFCAKPK_01665	2.67e-96	XK27_02735	-	-	K	-	-	-	Transcriptional regulator, MarR family
NHFCAKPK_01666	5.57e-180	phaB	5.3.3.14, 5.3.3.18	-	I	ko:K15866,ko:K18474	ko00061,ko00360,ko01120,map00061,map00360,map01120	ko00000,ko00001,ko01000,ko01004	Belongs to the enoyl-CoA hydratase isomerase family
NHFCAKPK_01667	1.52e-151	yhfA	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
NHFCAKPK_01668	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NHFCAKPK_01669	5.34e-245	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
NHFCAKPK_01670	7.59e-314	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHFCAKPK_01671	5.17e-175	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
NHFCAKPK_01672	1.99e-132	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
NHFCAKPK_01673	9.29e-134	-	-	-	S	-	-	-	Domain of unknown function (DUF1803)
NHFCAKPK_01674	2.51e-208	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
NHFCAKPK_01682	1.18e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHFCAKPK_01683	8.3e-128	comFC	-	-	K	ko:K02242	-	ko00000,ko00002,ko02044	competence protein
NHFCAKPK_01684	2.1e-304	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NHFCAKPK_01685	1.51e-140	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
NHFCAKPK_01686	3.47e-214	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NHFCAKPK_01687	1.04e-141	XK27_04065	-	-	S	ko:K04767	-	ko00000	CBS domain
NHFCAKPK_01688	4.6e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NHFCAKPK_01689	5.4e-175	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NHFCAKPK_01690	1.64e-184	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHFCAKPK_01691	9.55e-189	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHFCAKPK_01692	4.86e-268	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NHFCAKPK_01693	7.47e-63	ylbG	-	-	S	-	-	-	UPF0298 protein
NHFCAKPK_01694	9.54e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
NHFCAKPK_01695	3.75e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHFCAKPK_01696	1.06e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHFCAKPK_01697	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	G	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Belongs to the glycosyl hydrolase 68 family
NHFCAKPK_01698	0.0	-	3.2.1.26, 3.2.1.65	GH32	G	ko:K01193,ko:K01212	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NHFCAKPK_01699	1.35e-285	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NHFCAKPK_01700	1.39e-255	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NHFCAKPK_01701	0.0	pacL	-	-	P	-	-	-	cation transport ATPase
NHFCAKPK_01702	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
NHFCAKPK_01703	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHFCAKPK_01704	2.57e-239	femA	2.3.2.17	-	V	ko:K11694	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
NHFCAKPK_01705	2.28e-127	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NHFCAKPK_01706	5.68e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHFCAKPK_01707	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHFCAKPK_01708	1.66e-56	ylxQ	-	-	J	-	-	-	ribosomal protein
NHFCAKPK_01709	9.2e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Nucleic-acid-binding protein implicated in transcription termination
NHFCAKPK_01710	3.94e-258	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NHFCAKPK_01711	1.75e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NHFCAKPK_01712	2.59e-264	brpA	-	-	K	-	-	-	Transcriptional
NHFCAKPK_01713	1.57e-118	XK27_05885	2.3.1.82	-	M	ko:K18816	-	br01600,ko00000,ko01000,ko01504	phosphinothricin N-acetyltransferase activity
NHFCAKPK_01714	1.79e-100	ydiB	-	-	M	ko:K06925	-	ko00000,ko03016	ATPase or kinase
NHFCAKPK_01715	1.11e-314	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NHFCAKPK_01716	5.08e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
NHFCAKPK_01717	9.8e-177	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Metal-dependent hydrolase
NHFCAKPK_01718	9.54e-221	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHFCAKPK_01719	7.21e-170	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
NHFCAKPK_01720	7.17e-205	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
NHFCAKPK_01721	1.62e-87	manO	-	-	S	-	-	-	Protein conserved in bacteria
NHFCAKPK_01722	1.39e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHFCAKPK_01723	2.04e-167	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
NHFCAKPK_01724	1.22e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
NHFCAKPK_01725	7.55e-82	manO	-	-	S	-	-	-	protein conserved in bacteria
NHFCAKPK_01726	3.4e-298	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHFCAKPK_01727	5.06e-144	-	-	-	-	-	-	-	-
NHFCAKPK_01728	5.05e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NHFCAKPK_01729	2.54e-212	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NHFCAKPK_01730	2.48e-274	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
NHFCAKPK_01731	5.84e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHFCAKPK_01732	4.07e-119	covS	-	-	T	-	-	-	Histidine kinase
NHFCAKPK_01733	7.56e-218	covS	-	-	T	-	-	-	Histidine kinase
NHFCAKPK_01734	1.62e-159	csrR	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHFCAKPK_01735	6.59e-118	ylbN	-	-	K	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
NHFCAKPK_01736	3.39e-165	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Ribosomal RNA small subunit methyltransferase G
NHFCAKPK_01737	4.96e-301	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	COG0168 Trk-type K transport systems, membrane components
NHFCAKPK_01738	2.13e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
NHFCAKPK_01739	2.79e-188	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
NHFCAKPK_01740	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHFCAKPK_01741	8.98e-122	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
NHFCAKPK_01742	1.2e-201	ilvH	-	-	S	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
NHFCAKPK_01743	6.96e-266	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NHFCAKPK_01744	1.27e-152	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_01745	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHFCAKPK_01746	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NHFCAKPK_01747	2e-209	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
NHFCAKPK_01748	9.97e-185	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NHFCAKPK_01749	1.82e-165	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NHFCAKPK_01750	3.1e-172	nikQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport protein
NHFCAKPK_01751	4.11e-226	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
NHFCAKPK_01752	1.41e-203	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NHFCAKPK_01753	4.71e-142	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NHFCAKPK_01754	1.75e-167	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NHFCAKPK_01755	7.84e-101	ureE	-	-	O	ko:K03187	-	ko00000	enzyme active site formation
NHFCAKPK_01756	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NHFCAKPK_01757	3.78e-72	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
NHFCAKPK_01758	1.02e-61	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
NHFCAKPK_01759	2.16e-124	ureI	-	-	S	ko:K03191	ko05120,map05120	ko00000,ko00001,ko02000	AmiS/UreI family transporter
NHFCAKPK_01760	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4173)
NHFCAKPK_01761	1.09e-72	yhaI	-	-	L	-	-	-	Membrane
NHFCAKPK_01762	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHFCAKPK_01763	1.28e-200	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
NHFCAKPK_01764	2.14e-128	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Membrane-associated phospholipid phosphatase
NHFCAKPK_01765	2.29e-116	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHFCAKPK_01766	6.48e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHFCAKPK_01767	1.82e-310	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	Potassium transporter peripheral membrane component
NHFCAKPK_01768	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
NHFCAKPK_01769	4.11e-53	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
NHFCAKPK_01770	1.23e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NHFCAKPK_01771	1.64e-123	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHFCAKPK_01772	1.12e-154	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHFCAKPK_01773	4.75e-165	xerD	-	-	L	-	-	-	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NHFCAKPK_01774	5e-111	ykuL	-	-	S	-	-	-	CBS domain
NHFCAKPK_01775	1.03e-123	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NHFCAKPK_01776	5.88e-230	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHFCAKPK_01777	8.38e-192	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NHFCAKPK_01778	2.31e-48	-	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
NHFCAKPK_01779	3.65e-116	-	-	-	K	-	-	-	transcriptional regulator
NHFCAKPK_01780	9.58e-309	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHFCAKPK_01782	1.64e-143	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NHFCAKPK_01783	2.55e-121	XK27_09705	-	-	S	ko:K06950	-	ko00000	HD superfamily hydrolase
NHFCAKPK_01784	7.64e-166	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHFCAKPK_01785	2.63e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NHFCAKPK_01786	3.44e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHFCAKPK_01787	1.17e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHFCAKPK_01788	0.0	mltG	-	-	ADL	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NHFCAKPK_01789	5.79e-112	-	-	-	K	-	-	-	histone acetyltransferase HPA2 and related acetyltransferases
NHFCAKPK_01790	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NHFCAKPK_01791	3.69e-27	XK27_11680	-	-	-	-	-	-	-
NHFCAKPK_01792	0.0	snf	-	-	L	-	-	-	Superfamily II DNA RNA helicases, SNF2 family'
NHFCAKPK_01793	0.0	mapZ	-	-	D	ko:K20073	-	ko00000	Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NHFCAKPK_01794	5.28e-284	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NHFCAKPK_01795	1.89e-64	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHFCAKPK_01796	1.2e-121	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NHFCAKPK_01797	1.72e-141	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHFCAKPK_01798	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NHFCAKPK_01799	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
NHFCAKPK_01800	2.75e-95	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
NHFCAKPK_01801	6.89e-192	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NHFCAKPK_01802	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHFCAKPK_01803	8.31e-273	-	-	-	V	-	-	-	FtsX-like permease family
NHFCAKPK_01804	1.05e-154	-	-	-	V	-	-	-	abc transporter atp-binding protein
NHFCAKPK_01805	5.36e-157	mta	-	-	K	ko:K21743	-	ko00000,ko03000	Transcriptional
NHFCAKPK_01806	3.15e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NHFCAKPK_01807	1.15e-98	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
NHFCAKPK_01808	7.19e-177	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
NHFCAKPK_01809	3.25e-193	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_01810	1.6e-67	-	-	-	K	-	-	-	regulation of RNA biosynthetic process
NHFCAKPK_01811	1.14e-63	-	3.2.2.21	-	S	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	YCII-related domain
NHFCAKPK_01812	2e-65	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
NHFCAKPK_01813	8.91e-289	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
NHFCAKPK_01814	8.75e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NHFCAKPK_01815	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NHFCAKPK_01816	6.26e-170	-	-	-	K	ko:K22103	-	ko00000,ko03000	transcriptional regulator (DeoR family)
NHFCAKPK_01817	4.99e-183	cof	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NHFCAKPK_01818	3.3e-94	-	3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27	-	I	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
NHFCAKPK_01819	2.8e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NHFCAKPK_01820	1.05e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Belongs to the SecE SEC61-gamma family
NHFCAKPK_01821	2.73e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NHFCAKPK_01822	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NHFCAKPK_01823	3.19e-205	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NHFCAKPK_01824	5.41e-73	WQ51_06355	-	-	S	-	-	-	TM2 domain
NHFCAKPK_01825	4.19e-60	-	-	-	-	-	-	-	-
NHFCAKPK_01827	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHFCAKPK_01828	7.72e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHFCAKPK_01829	8.63e-183	cmpC	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
NHFCAKPK_01830	0.0	XK27_00665	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
NHFCAKPK_01831	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHFCAKPK_01832	5.21e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NHFCAKPK_01833	2.05e-184	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NHFCAKPK_01834	1.02e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHFCAKPK_01835	2.45e-61	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
NHFCAKPK_01836	2.37e-161	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
NHFCAKPK_01837	5.62e-79	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
NHFCAKPK_01838	1.15e-27	-	-	-	H	-	-	-	Transaldolase
NHFCAKPK_01839	1.89e-44	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	sorbitol-specific, IIA component
NHFCAKPK_01840	6.08e-200	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS sorbitol transporter subunit IIB
NHFCAKPK_01841	9.08e-106	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system glucitol sorbitol-specific
NHFCAKPK_01842	1.16e-73	srlR	-	-	K	-	-	-	Glucitol operon activator
NHFCAKPK_01844	3.98e-135	sorD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHFCAKPK_01845	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHFCAKPK_01846	2.7e-296	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NHFCAKPK_01847	4.78e-201	rgfB	3.1.3.90	-	L	ko:K06896	ko00500,map00500	ko00000,ko00001,ko01000	Endonuclease/Exonuclease/phosphatase family
NHFCAKPK_01848	0.0	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
NHFCAKPK_01849	3.03e-202	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
NHFCAKPK_01850	2.99e-164	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
NHFCAKPK_01851	1.7e-173	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NHFCAKPK_01852	2.49e-92	adcR	-	-	K	-	-	-	transcriptional
NHFCAKPK_01853	2.41e-233	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHFCAKPK_01854	2.6e-199	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHFCAKPK_01855	2.48e-34	-	-	-	-	-	-	-	-
NHFCAKPK_01856	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
NHFCAKPK_01857	4.28e-97	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NHFCAKPK_01858	9.85e-302	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHFCAKPK_01859	1.98e-297	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
NHFCAKPK_01860	1.65e-176	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NHFCAKPK_01861	3.65e-241	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
NHFCAKPK_01862	1.21e-164	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NHFCAKPK_01864	1.75e-195	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NHFCAKPK_01865	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NHFCAKPK_01866	4.26e-168	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
NHFCAKPK_01867	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
NHFCAKPK_01868	5.27e-126	-	-	-	V	-	-	-	VanZ like family
NHFCAKPK_01869	3.52e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHFCAKPK_01870	9.39e-244	XK27_00055	-	-	P	-	-	-	Major Facilitator
NHFCAKPK_01871	3.84e-145	-	-	-	K	-	-	-	Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NHFCAKPK_01872	5.97e-145	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHFCAKPK_01873	3.18e-301	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NHFCAKPK_01874	0.0	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
NHFCAKPK_01875	1.94e-95	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHFCAKPK_01876	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHFCAKPK_01877	6.05e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NHFCAKPK_01878	0.0	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NHFCAKPK_01879	1.08e-166	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHFCAKPK_01880	3.36e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
NHFCAKPK_01881	1.94e-100	-	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NHFCAKPK_01882	2.5e-109	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
NHFCAKPK_01883	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHFCAKPK_01884	1.44e-100	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NHFCAKPK_01885	1.28e-292	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHFCAKPK_01886	8.87e-174	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
NHFCAKPK_01887	3.77e-113	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
NHFCAKPK_01888	1.33e-156	-	-	-	L	-	-	-	Helix-turn-helix domain
NHFCAKPK_01889	5.94e-196	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
NHFCAKPK_01892	4.13e-104	hmpT	-	-	S	-	-	-	cog cog4720
NHFCAKPK_01893	9.68e-173	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	phosphomethylpyrimidine kinase
NHFCAKPK_01894	6.12e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHFCAKPK_01895	6.04e-252	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHFCAKPK_01897	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NHFCAKPK_01898	2.11e-103	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHFCAKPK_01899	5.47e-236	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHFCAKPK_01900	4.75e-130	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Muramidase (Flagellum-specific)
NHFCAKPK_01901	5.58e-178	yodJ	3.4.16.4, 3.4.17.14	-	M	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
NHFCAKPK_01902	5.22e-165	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase
NHFCAKPK_01903	6.05e-307	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NHFCAKPK_01904	2.5e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	UPF0237 protein
NHFCAKPK_01905	2.57e-296	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
NHFCAKPK_01906	6.12e-193	srtB	-	-	S	-	-	-	Sortase family
NHFCAKPK_01908	3.54e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
NHFCAKPK_01913	1.05e-29	int	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NHFCAKPK_01914	4.82e-71	-	-	-	S	-	-	-	Toxin-antitoxin system, toxin component, RelE family
NHFCAKPK_01915	1.66e-56	-	-	-	K	-	-	-	Helix-turn-helix domain
NHFCAKPK_01916	1.51e-132	salR	-	-	K	ko:K14989	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
NHFCAKPK_01917	1.6e-316	-	-	-	T	ko:K14988	ko02020,map02020	ko00000,ko00001,ko00002,ko01001,ko02022	Histidine kinase
NHFCAKPK_01918	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHFCAKPK_01919	1.52e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NHFCAKPK_01920	3.49e-41	cro	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
NHFCAKPK_01921	2.05e-72	hxlR	-	-	K	-	-	-	HxlR-like helix-turn-helix
NHFCAKPK_01923	3.07e-301	mmr	-	-	P	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
NHFCAKPK_01924	2.12e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NHFCAKPK_01925	7.02e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHFCAKPK_01926	1.21e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
NHFCAKPK_01928	2.05e-195	yitS	-	-	S	-	-	-	DegV family
NHFCAKPK_01929	5.73e-120	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
NHFCAKPK_01930	1.75e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHFCAKPK_01932	1.22e-89	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NHFCAKPK_01933	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NHFCAKPK_01934	4.02e-144	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
NHFCAKPK_01935	1.18e-179	-	-	-	S	-	-	-	SseB protein N-terminal domain
NHFCAKPK_01936	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NHFCAKPK_01937	1.64e-286	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NHFCAKPK_01938	1.53e-292	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NHFCAKPK_01939	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
NHFCAKPK_01940	1.92e-97	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NHFCAKPK_01941	3.41e-107	-	-	-	S	-	-	-	Putative small multi-drug export protein
NHFCAKPK_01942	1.23e-233	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHFCAKPK_01943	2.48e-176	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NHFCAKPK_01944	4.96e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	alkyl hydroperoxide reductase
NHFCAKPK_01945	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	alkyl hydroperoxide reductase
NHFCAKPK_01947	8.98e-122	XK27_03570	-	-	S	ko:K19784	-	ko00000	reductase
NHFCAKPK_01948	1.89e-95	-	-	-	K	-	-	-	Transcriptional regulator, marr family
NHFCAKPK_01949	1.4e-48	XK27_02060	-	-	S	-	-	-	Transglycosylase associated protein
NHFCAKPK_01950	1.25e-301	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
NHFCAKPK_01951	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHFCAKPK_01965	8.92e-87	spxA_2	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
NHFCAKPK_01966	4.16e-260	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHFCAKPK_01967	7.25e-285	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NHFCAKPK_01968	5.31e-135	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	3-methyladenine DNA glycosylase
NHFCAKPK_01969	1.47e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHFCAKPK_01971	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHFCAKPK_01973	5.36e-92	-	-	-	K	-	-	-	LytTr DNA-binding domain
NHFCAKPK_01974	7.24e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NHFCAKPK_01975	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHFCAKPK_01976	1.23e-71	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
NHFCAKPK_01977	4.46e-89	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NHFCAKPK_01978	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NHFCAKPK_01981	1.7e-17	-	-	-	-	-	-	-	-
NHFCAKPK_01982	1.75e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHFCAKPK_01983	1.51e-164	-	-	-	-	-	-	-	-
NHFCAKPK_01984	3.29e-258	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHFCAKPK_01985	5.15e-105	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHFCAKPK_01986	4.54e-303	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NHFCAKPK_01987	7.44e-200	-	-	-	S	-	-	-	CHAP domain
NHFCAKPK_01988	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NHFCAKPK_01989	3.96e-131	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHFCAKPK_01990	2.84e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NHFCAKPK_01991	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHFCAKPK_01992	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHFCAKPK_01993	8.69e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NHFCAKPK_01994	4.06e-39	acpP_1	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHFCAKPK_01995	1.19e-234	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHFCAKPK_01996	1.74e-177	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NHFCAKPK_01997	1.23e-274	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NHFCAKPK_01998	1.36e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHFCAKPK_01999	1.75e-145	pcsB	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
NHFCAKPK_02000	1.18e-109	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
NHFCAKPK_02001	2.38e-157	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NHFCAKPK_02020	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHFCAKPK_02021	5.23e-125	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
NHFCAKPK_02022	8.93e-290	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHFCAKPK_02023	6.14e-297	-	3.5.2.6	-	V	ko:K01467	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01000	Beta-lactamase enzyme family
NHFCAKPK_02024	1.36e-05	-	-	-	-	-	-	-	-
NHFCAKPK_02025	3.9e-79	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
NHFCAKPK_02026	7.62e-53	yabO	-	-	J	-	-	-	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NHFCAKPK_02027	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHFCAKPK_02028	5.18e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHFCAKPK_02029	7.47e-259	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHFCAKPK_02030	8.11e-40	yyzM	-	-	S	-	-	-	Protein conserved in bacteria