ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
IELDDGJM_00001 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IELDDGJM_00002 1.72e-88 - - - S - - - YusW-like protein
IELDDGJM_00003 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
IELDDGJM_00004 3.29e-194 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IELDDGJM_00005 2.15e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
IELDDGJM_00006 9.21e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IELDDGJM_00007 6.4e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IELDDGJM_00008 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_00009 3.06e-204 yuxN - - K - - - Transcriptional regulator
IELDDGJM_00010 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IELDDGJM_00011 2.6e-33 - - - S - - - Protein of unknown function (DUF3970)
IELDDGJM_00012 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IELDDGJM_00013 2.18e-248 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IELDDGJM_00014 5.63e-239 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
IELDDGJM_00015 8.64e-137 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IELDDGJM_00016 4.54e-243 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_00017 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
IELDDGJM_00018 1.21e-173 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
IELDDGJM_00019 5.51e-140 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IELDDGJM_00020 1.07e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
IELDDGJM_00021 1.53e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IELDDGJM_00022 7.88e-131 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
IELDDGJM_00023 5.43e-311 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IELDDGJM_00024 1.56e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IELDDGJM_00025 2.98e-218 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IELDDGJM_00026 1.18e-178 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IELDDGJM_00027 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
IELDDGJM_00028 0.0 yvrG - - T - - - Histidine kinase
IELDDGJM_00029 3.16e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IELDDGJM_00030 5.07e-32 - - - - - - - -
IELDDGJM_00031 4.55e-124 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
IELDDGJM_00032 6.98e-26 - - - S - - - YvrJ protein family
IELDDGJM_00033 2.17e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IELDDGJM_00034 6.69e-84 yvrL - - S - - - Regulatory protein YrvL
IELDDGJM_00035 2.76e-271 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IELDDGJM_00036 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_00037 1.4e-228 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
IELDDGJM_00038 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IELDDGJM_00039 6.5e-224 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IELDDGJM_00040 3.32e-234 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IELDDGJM_00041 6.32e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IELDDGJM_00042 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
IELDDGJM_00043 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
IELDDGJM_00044 6.83e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
IELDDGJM_00045 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
IELDDGJM_00046 4.91e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
IELDDGJM_00047 2.56e-176 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
IELDDGJM_00048 7.09e-153 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
IELDDGJM_00049 2.52e-200 yvgN - - S - - - reductase
IELDDGJM_00050 7.97e-113 yvgO - - - - - - -
IELDDGJM_00051 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
IELDDGJM_00052 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IELDDGJM_00053 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IELDDGJM_00054 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IELDDGJM_00055 3.88e-140 yvgT - - S - - - membrane
IELDDGJM_00056 1.15e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
IELDDGJM_00057 1.71e-137 bdbD - - O - - - Thioredoxin
IELDDGJM_00058 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IELDDGJM_00059 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
IELDDGJM_00060 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
IELDDGJM_00061 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
IELDDGJM_00062 1.89e-242 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IELDDGJM_00063 2.95e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IELDDGJM_00064 0.0 - - - S - - - Fusaric acid resistance protein-like
IELDDGJM_00065 8.22e-97 yvaD - - S - - - Family of unknown function (DUF5360)
IELDDGJM_00066 2.04e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
IELDDGJM_00067 1.42e-127 - - - K - - - Bacterial regulatory proteins, tetR family
IELDDGJM_00068 4.37e-120 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IELDDGJM_00069 3.65e-19 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IELDDGJM_00071 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IELDDGJM_00072 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IELDDGJM_00073 2.82e-182 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
IELDDGJM_00074 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
IELDDGJM_00075 1.16e-193 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
IELDDGJM_00076 4.9e-48 yvzC - - K - - - transcriptional
IELDDGJM_00077 6.83e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
IELDDGJM_00078 2.82e-91 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
IELDDGJM_00079 3.85e-72 yvaP - - K - - - transcriptional
IELDDGJM_00080 3.65e-24 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IELDDGJM_00081 8.68e-45 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IELDDGJM_00082 2.34e-164 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IELDDGJM_00083 1.07e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IELDDGJM_00084 2.37e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IELDDGJM_00085 2.57e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IELDDGJM_00086 3.34e-267 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IELDDGJM_00087 1.9e-121 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IELDDGJM_00088 2.75e-11 - - - S - - - Sporulation delaying protein SdpA
IELDDGJM_00089 1.13e-222 - - - - - - - -
IELDDGJM_00091 8.32e-133 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
IELDDGJM_00092 9.63e-60 sdpR - - K - - - transcriptional
IELDDGJM_00093 1.03e-146 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IELDDGJM_00094 5e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IELDDGJM_00095 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IELDDGJM_00096 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IELDDGJM_00097 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IELDDGJM_00098 1.32e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
IELDDGJM_00099 5.2e-139 yvbH - - S - - - YvbH-like oligomerisation region
IELDDGJM_00100 3.11e-154 yvbI - - M - - - Membrane
IELDDGJM_00101 2.7e-56 tcaA - - S ko:K21463 - ko00000 response to antibiotic
IELDDGJM_00102 4.45e-241 tcaA - - S ko:K21463 - ko00000 response to antibiotic
IELDDGJM_00103 2.9e-98 yvbK - - K - - - acetyltransferase
IELDDGJM_00104 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IELDDGJM_00105 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
IELDDGJM_00106 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IELDDGJM_00107 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
IELDDGJM_00108 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IELDDGJM_00109 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IELDDGJM_00110 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IELDDGJM_00111 1.76e-257 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
IELDDGJM_00112 6.01e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IELDDGJM_00113 4.7e-204 yvbU - - K - - - Transcriptional regulator
IELDDGJM_00114 1.13e-197 yvbV - - EG - - - EamA-like transporter family
IELDDGJM_00115 3.02e-234 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IELDDGJM_00116 1.62e-45 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IELDDGJM_00117 1.94e-245 - - - S - - - Glycosyl hydrolase
IELDDGJM_00118 8.37e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IELDDGJM_00119 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IELDDGJM_00120 1.51e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IELDDGJM_00121 2.74e-38 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IELDDGJM_00123 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
IELDDGJM_00124 1.41e-254 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
IELDDGJM_00125 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
IELDDGJM_00126 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
IELDDGJM_00127 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
IELDDGJM_00128 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
IELDDGJM_00129 1.88e-291 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
IELDDGJM_00130 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_00131 1.18e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
IELDDGJM_00132 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IELDDGJM_00133 9.59e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IELDDGJM_00134 5.69e-44 yvfG - - S - - - YvfG protein
IELDDGJM_00135 3.07e-240 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
IELDDGJM_00136 6.12e-278 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
IELDDGJM_00137 5.02e-78 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IELDDGJM_00138 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IELDDGJM_00139 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IELDDGJM_00140 1.31e-243 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IELDDGJM_00141 1.34e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
IELDDGJM_00142 1.22e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IELDDGJM_00143 1.46e-263 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
IELDDGJM_00144 1.69e-276 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IELDDGJM_00145 1.03e-200 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
IELDDGJM_00146 1.5e-279 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
IELDDGJM_00147 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IELDDGJM_00148 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IELDDGJM_00149 3.94e-156 epsA - - M ko:K19420 - ko00000 biosynthesis protein
IELDDGJM_00150 4.17e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
IELDDGJM_00151 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
IELDDGJM_00153 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
IELDDGJM_00154 3.99e-95 - - - S - - - Protein of unknown function (DUF3237)
IELDDGJM_00155 2.3e-158 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
IELDDGJM_00156 0.0 pbpE - - V - - - Beta-lactamase
IELDDGJM_00157 1.34e-213 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
IELDDGJM_00158 1.04e-106 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
IELDDGJM_00159 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IELDDGJM_00160 0.0 ybeC - - E - - - amino acid
IELDDGJM_00161 1.94e-136 yvdT_1 - - K - - - Transcriptional regulator
IELDDGJM_00162 1.74e-65 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IELDDGJM_00163 4.21e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
IELDDGJM_00164 3.19e-95 yvdQ - - S - - - Protein of unknown function (DUF3231)
IELDDGJM_00166 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IELDDGJM_00167 7.59e-147 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IELDDGJM_00168 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IELDDGJM_00169 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
IELDDGJM_00170 5.63e-197 malA - - S - - - Protein of unknown function (DUF1189)
IELDDGJM_00171 6.56e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
IELDDGJM_00172 2.48e-310 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
IELDDGJM_00173 3.44e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
IELDDGJM_00174 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
IELDDGJM_00175 6.55e-223 yvdE - - K - - - Transcriptional regulator
IELDDGJM_00176 3.11e-136 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
IELDDGJM_00177 3.2e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
IELDDGJM_00178 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IELDDGJM_00179 5.3e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IELDDGJM_00180 2.32e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IELDDGJM_00181 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
IELDDGJM_00182 2.58e-180 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_00183 4.61e-250 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
IELDDGJM_00184 2.22e-170 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IELDDGJM_00185 3.24e-44 - - - - - - - -
IELDDGJM_00186 2.3e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
IELDDGJM_00187 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
IELDDGJM_00188 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
IELDDGJM_00189 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
IELDDGJM_00190 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
IELDDGJM_00191 9.76e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IELDDGJM_00192 6.83e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IELDDGJM_00193 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
IELDDGJM_00194 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
IELDDGJM_00195 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
IELDDGJM_00197 4.31e-313 - - - - - - - -
IELDDGJM_00198 4.82e-104 - - - - - - - -
IELDDGJM_00199 3.05e-145 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
IELDDGJM_00200 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IELDDGJM_00201 6.55e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IELDDGJM_00202 1.2e-148 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IELDDGJM_00203 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
IELDDGJM_00204 6.33e-293 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IELDDGJM_00205 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IELDDGJM_00206 3.29e-279 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IELDDGJM_00207 1.44e-177 yvpB - - NU - - - protein conserved in bacteria
IELDDGJM_00208 3.15e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
IELDDGJM_00209 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IELDDGJM_00210 1.06e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IELDDGJM_00211 3.72e-211 yvoD - - P - - - COG0370 Fe2 transport system protein B
IELDDGJM_00212 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IELDDGJM_00213 1.47e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IELDDGJM_00214 5.07e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
IELDDGJM_00215 2.88e-164 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IELDDGJM_00216 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
IELDDGJM_00217 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
IELDDGJM_00218 7.73e-109 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
IELDDGJM_00219 9.32e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IELDDGJM_00220 8.35e-176 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
IELDDGJM_00221 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
IELDDGJM_00222 2.87e-270 yvmA - - EGP - - - Major Facilitator Superfamily
IELDDGJM_00223 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
IELDDGJM_00224 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
IELDDGJM_00225 9.59e-220 yvlB - - S - - - Putative adhesin
IELDDGJM_00226 8.09e-65 yvlA - - - - - - -
IELDDGJM_00227 2.25e-45 yvkN - - - - - - -
IELDDGJM_00228 4.93e-64 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IELDDGJM_00229 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IELDDGJM_00230 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IELDDGJM_00231 2.54e-42 csbA - - S - - - protein conserved in bacteria
IELDDGJM_00232 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
IELDDGJM_00233 4.77e-130 yvkB - - K - - - Transcriptional regulator
IELDDGJM_00234 5.24e-296 yvkA - - P - - - -transporter
IELDDGJM_00235 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IELDDGJM_00236 1.38e-73 swrA - - S - - - Swarming motility protein
IELDDGJM_00237 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IELDDGJM_00238 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IELDDGJM_00239 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
IELDDGJM_00240 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IELDDGJM_00241 1.31e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IELDDGJM_00242 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IELDDGJM_00243 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IELDDGJM_00244 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IELDDGJM_00245 2.46e-67 - - - - - - - -
IELDDGJM_00246 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
IELDDGJM_00247 6.02e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
IELDDGJM_00248 2.21e-313 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IELDDGJM_00249 9.77e-71 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
IELDDGJM_00250 7.45e-148 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IELDDGJM_00251 4.29e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IELDDGJM_00252 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IELDDGJM_00253 1.7e-92 yviE - - - - - - -
IELDDGJM_00254 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
IELDDGJM_00255 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
IELDDGJM_00256 1e-101 yvyG - - NOU - - - FlgN protein
IELDDGJM_00257 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
IELDDGJM_00258 3.05e-95 yvyF - - S - - - flagellar protein
IELDDGJM_00259 8.46e-158 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
IELDDGJM_00260 2.5e-44 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
IELDDGJM_00261 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IELDDGJM_00262 2.93e-197 degV - - S - - - protein conserved in bacteria
IELDDGJM_00263 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IELDDGJM_00264 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IELDDGJM_00265 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
IELDDGJM_00266 2.68e-223 yvhJ - - K - - - Transcriptional regulator
IELDDGJM_00267 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IELDDGJM_00268 2.49e-298 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
IELDDGJM_00269 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IELDDGJM_00270 2.02e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
IELDDGJM_00271 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
IELDDGJM_00272 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IELDDGJM_00273 1.63e-278 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
IELDDGJM_00274 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IELDDGJM_00275 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IELDDGJM_00276 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IELDDGJM_00277 0.0 lytB - - D - - - Stage II sporulation protein
IELDDGJM_00278 3.26e-50 - - - - - - - -
IELDDGJM_00279 1.13e-218 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IELDDGJM_00280 2.58e-275 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IELDDGJM_00281 2.53e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IELDDGJM_00282 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IELDDGJM_00283 0.0 - - - M - - - Glycosyltransferase like family 2
IELDDGJM_00284 5.43e-05 - 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase-like
IELDDGJM_00285 2.13e-127 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IELDDGJM_00286 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IELDDGJM_00287 2.06e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
IELDDGJM_00288 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IELDDGJM_00289 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
IELDDGJM_00290 3.82e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
IELDDGJM_00291 1.9e-185 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IELDDGJM_00292 3.8e-273 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IELDDGJM_00293 0.0 - - - - - - - -
IELDDGJM_00294 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IELDDGJM_00295 1.3e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IELDDGJM_00296 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IELDDGJM_00297 2.86e-246 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IELDDGJM_00298 1.25e-263 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
IELDDGJM_00299 1.06e-313 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IELDDGJM_00300 2.11e-222 ywtF_2 - - K - - - Transcriptional regulator
IELDDGJM_00301 2.95e-204 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IELDDGJM_00302 1.13e-11 - - - S - - - YpzI-like protein
IELDDGJM_00303 2.62e-132 yphA - - - - - - -
IELDDGJM_00304 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
IELDDGJM_00305 1.02e-38 ypzH - - - - - - -
IELDDGJM_00306 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
IELDDGJM_00307 8.18e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
IELDDGJM_00308 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
IELDDGJM_00309 1.02e-174 yphF - - - - - - -
IELDDGJM_00310 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IELDDGJM_00311 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IELDDGJM_00312 6.02e-129 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
IELDDGJM_00313 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IELDDGJM_00314 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IELDDGJM_00315 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IELDDGJM_00316 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IELDDGJM_00317 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IELDDGJM_00318 1.23e-181 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
IELDDGJM_00319 1.19e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IELDDGJM_00320 6.68e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IELDDGJM_00321 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IELDDGJM_00322 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IELDDGJM_00323 9.65e-227 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IELDDGJM_00324 2.07e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
IELDDGJM_00325 4.5e-150 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
IELDDGJM_00326 4.25e-291 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IELDDGJM_00327 1.82e-184 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IELDDGJM_00328 6.13e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IELDDGJM_00329 9.9e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
IELDDGJM_00330 3.17e-298 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IELDDGJM_00331 5.05e-297 ypiA - - S - - - COG0457 FOG TPR repeat
IELDDGJM_00332 7.45e-129 ypiB - - S - - - Belongs to the UPF0302 family
IELDDGJM_00333 7.88e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
IELDDGJM_00334 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
IELDDGJM_00335 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
IELDDGJM_00336 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
IELDDGJM_00337 1.2e-127 ypjA - - S - - - membrane
IELDDGJM_00338 6.84e-183 ypjB - - S - - - sporulation protein
IELDDGJM_00339 2.14e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IELDDGJM_00340 5.83e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
IELDDGJM_00341 1.39e-188 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IELDDGJM_00342 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
IELDDGJM_00343 7.71e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
IELDDGJM_00344 2.34e-265 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
IELDDGJM_00345 1.02e-276 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IELDDGJM_00346 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IELDDGJM_00347 9.79e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IELDDGJM_00348 1.83e-198 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IELDDGJM_00349 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IELDDGJM_00350 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
IELDDGJM_00351 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
IELDDGJM_00352 2.27e-103 ypmB - - S - - - protein conserved in bacteria
IELDDGJM_00353 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IELDDGJM_00354 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
IELDDGJM_00355 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
IELDDGJM_00356 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IELDDGJM_00357 1.43e-121 ypoC - - - - - - -
IELDDGJM_00358 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IELDDGJM_00359 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IELDDGJM_00360 4.54e-241 yppC - - S - - - Protein of unknown function (DUF2515)
IELDDGJM_00363 5.61e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
IELDDGJM_00364 9.21e-11 - - - S - - - YppF-like protein
IELDDGJM_00365 1.45e-66 yppG - - S - - - YppG-like protein
IELDDGJM_00366 1.45e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IELDDGJM_00367 2.13e-109 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
IELDDGJM_00368 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IELDDGJM_00369 1.63e-297 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
IELDDGJM_00370 3.99e-127 ypsA - - S - - - Belongs to the UPF0398 family
IELDDGJM_00371 1.72e-59 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IELDDGJM_00372 8.14e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
IELDDGJM_00374 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
IELDDGJM_00375 2.29e-176 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IELDDGJM_00376 2.96e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IELDDGJM_00377 7.8e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
IELDDGJM_00378 4.02e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
IELDDGJM_00379 5.97e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
IELDDGJM_00380 3.54e-152 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
IELDDGJM_00381 8.1e-35 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
IELDDGJM_00382 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IELDDGJM_00383 3.19e-126 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IELDDGJM_00384 2.47e-291 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
IELDDGJM_00385 1.31e-262 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
IELDDGJM_00386 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
IELDDGJM_00387 0.0 ypbR - - S - - - Dynamin family
IELDDGJM_00388 5.79e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
IELDDGJM_00389 7.57e-12 - - - - - - - -
IELDDGJM_00390 2.26e-213 ypcP - - L - - - 5'3' exonuclease
IELDDGJM_00391 5.23e-05 - - - - ko:K06429 - ko00000 -
IELDDGJM_00392 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
IELDDGJM_00393 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IELDDGJM_00394 2.31e-162 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
IELDDGJM_00395 7.99e-41 ypeQ - - S - - - Zinc-finger
IELDDGJM_00396 1.5e-40 - - - S - - - Protein of unknown function (DUF2564)
IELDDGJM_00397 1.67e-22 degR - - - - - - -
IELDDGJM_00398 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
IELDDGJM_00399 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IELDDGJM_00400 5e-224 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IELDDGJM_00401 3.66e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
IELDDGJM_00402 5.94e-141 yagB - - S ko:K06950 - ko00000 phosphohydrolase
IELDDGJM_00403 1.15e-203 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
IELDDGJM_00404 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
IELDDGJM_00405 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
IELDDGJM_00406 4.65e-182 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
IELDDGJM_00407 5.75e-147 ypjP - - S - - - YpjP-like protein
IELDDGJM_00408 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
IELDDGJM_00409 2.43e-201 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IELDDGJM_00410 9.58e-122 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IELDDGJM_00411 3.86e-142 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IELDDGJM_00412 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
IELDDGJM_00413 1.34e-234 yplP - - K - - - Transcriptional regulator
IELDDGJM_00414 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IELDDGJM_00415 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
IELDDGJM_00416 5.15e-136 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IELDDGJM_00417 1.05e-177 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
IELDDGJM_00418 1.95e-128 ypmS - - S - - - protein conserved in bacteria
IELDDGJM_00419 1.24e-39 ypmT - - S - - - Uncharacterized ympT
IELDDGJM_00420 1.65e-288 mepA - - V - - - MATE efflux family protein
IELDDGJM_00421 6.17e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
IELDDGJM_00422 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
IELDDGJM_00423 5.47e-117 - - - P - - - Catalase
IELDDGJM_00424 8.77e-99 - - - S - - - Protein of unknown function (DUF421)
IELDDGJM_00429 3.01e-25 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IELDDGJM_00430 5.98e-143 - - - S - - - Thymidylate synthase
IELDDGJM_00431 1.33e-78 - - - S - - - membrane
IELDDGJM_00438 1.09e-94 - - - L ko:K07497 - ko00000 Integrase core domain
IELDDGJM_00439 3.26e-72 - - - L - - - transposase activity
IELDDGJM_00440 5.07e-38 yetM - - CH - - - FAD binding domain
IELDDGJM_00441 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
IELDDGJM_00442 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
IELDDGJM_00443 4.18e-183 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IELDDGJM_00444 4.36e-41 - - - - - - - -
IELDDGJM_00445 3.51e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IELDDGJM_00446 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
IELDDGJM_00447 7.07e-155 yetF - - S - - - membrane
IELDDGJM_00448 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
IELDDGJM_00449 1.3e-207 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IELDDGJM_00450 2.39e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
IELDDGJM_00451 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IELDDGJM_00452 1.03e-226 yetA - - - - - - -
IELDDGJM_00453 4.85e-317 yetA - - - - - - -
IELDDGJM_00454 1.7e-192 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
IELDDGJM_00455 2.38e-152 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
IELDDGJM_00456 5.39e-80 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
IELDDGJM_00457 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
IELDDGJM_00458 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
IELDDGJM_00459 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
IELDDGJM_00460 2.32e-144 - - - S - - - Protein of unknown function, DUF624
IELDDGJM_00461 4.18e-162 yesU - - S - - - Domain of unknown function (DUF1961)
IELDDGJM_00462 2.06e-170 - - - E - - - GDSL-like Lipase/Acylhydrolase
IELDDGJM_00463 0.0 yesS - - K - - - Transcriptional regulator
IELDDGJM_00464 4.63e-253 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
IELDDGJM_00465 1.15e-206 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IELDDGJM_00466 1.66e-217 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IELDDGJM_00467 9.72e-313 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
IELDDGJM_00468 1.01e-252 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
IELDDGJM_00469 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_00470 7.03e-130 yesL - - S - - - Protein of unknown function, DUF624
IELDDGJM_00472 2.22e-126 yesJ - - K - - - Acetyltransferase (GNAT) family
IELDDGJM_00473 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
IELDDGJM_00474 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
IELDDGJM_00475 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
IELDDGJM_00476 7.31e-41 yesF - - GM - - - NAD(P)H-binding
IELDDGJM_00477 6.57e-23 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
IELDDGJM_00478 7.83e-127 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_00480 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
IELDDGJM_00482 1.73e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
IELDDGJM_00483 1.06e-73 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
IELDDGJM_00484 2.38e-121 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
IELDDGJM_00485 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
IELDDGJM_00486 1.73e-108 - - - S - - - Protein of unknown function, DUF600
IELDDGJM_00488 4e-40 - - - S - - - Colicin immunity protein / pyocin immunity protein
IELDDGJM_00490 7.38e-123 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IELDDGJM_00492 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IELDDGJM_00493 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IELDDGJM_00494 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IELDDGJM_00495 3.45e-189 yerO - - K - - - Transcriptional regulator
IELDDGJM_00496 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IELDDGJM_00497 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IELDDGJM_00498 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IELDDGJM_00499 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IELDDGJM_00500 3.25e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
IELDDGJM_00501 2.35e-248 yerI - - S - - - homoserine kinase type II (protein kinase fold)
IELDDGJM_00502 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
IELDDGJM_00503 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IELDDGJM_00504 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
IELDDGJM_00505 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IELDDGJM_00506 4.95e-39 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
IELDDGJM_00507 4.99e-250 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
IELDDGJM_00508 7.62e-68 yerC - - S - - - protein conserved in bacteria
IELDDGJM_00509 6.47e-242 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
IELDDGJM_00510 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
IELDDGJM_00511 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
IELDDGJM_00512 1.06e-294 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
IELDDGJM_00513 4.51e-95 - - - K - - - helix_turn_helix ASNC type
IELDDGJM_00514 4.88e-299 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
IELDDGJM_00515 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
IELDDGJM_00516 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IELDDGJM_00517 9.47e-238 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
IELDDGJM_00518 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IELDDGJM_00519 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IELDDGJM_00520 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IELDDGJM_00521 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IELDDGJM_00522 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
IELDDGJM_00523 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IELDDGJM_00524 4.28e-274 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IELDDGJM_00525 9.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IELDDGJM_00526 3.13e-38 yebG - - S - - - NETI protein
IELDDGJM_00527 2.66e-120 yebE - - S - - - UPF0316 protein
IELDDGJM_00529 1.95e-163 yebC - - M - - - Membrane
IELDDGJM_00530 4.65e-281 pbuG - - S ko:K06901 - ko00000,ko02000 permease
IELDDGJM_00532 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
IELDDGJM_00533 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
IELDDGJM_00534 1.07e-283 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IELDDGJM_00535 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
IELDDGJM_00536 4.82e-196 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IELDDGJM_00537 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IELDDGJM_00538 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
IELDDGJM_00539 2.9e-228 yeaA - - S - - - Protein of unknown function (DUF4003)
IELDDGJM_00540 2.95e-201 - - - I - - - Alpha/beta hydrolase family
IELDDGJM_00541 9.99e-48 ydjO - - S - - - Cold-inducible protein YdjO
IELDDGJM_00543 7.55e-59 orfX1 - - L - - - Transposase
IELDDGJM_00547 1.42e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IELDDGJM_00548 9.14e-122 xkdA - - E - - - IrrE N-terminal-like domain
IELDDGJM_00549 4.16e-130 yqaC - - F - - - adenylate kinase activity
IELDDGJM_00551 1.88e-42 - - - K - - - sequence-specific DNA binding
IELDDGJM_00552 1.02e-24 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
IELDDGJM_00554 1.04e-133 - - - - - - - -
IELDDGJM_00558 3.76e-219 yqaJ - - L - - - YqaJ-like viral recombinase domain
IELDDGJM_00559 4.79e-136 recT - - L ko:K07455 - ko00000,ko03400 RecT family
IELDDGJM_00560 4.44e-40 recT - - L ko:K07455 - ko00000,ko03400 RecT family
IELDDGJM_00561 8.41e-153 yqaL - - L - - - DnaD domain protein
IELDDGJM_00562 2.72e-211 yqaM - - L - - - IstB-like ATP binding protein
IELDDGJM_00564 5.21e-93 rusA - - L - - - Endodeoxyribonuclease RusA
IELDDGJM_00565 1.24e-41 yqaO - - S - - - Phage-like element PBSX protein XtrA
IELDDGJM_00568 8.46e-101 yqaQ - - L - - - Transposase
IELDDGJM_00571 5.44e-147 yqaS - - L - - - DNA packaging
IELDDGJM_00572 3.86e-316 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
IELDDGJM_00573 0.0 yqbA - - S - - - portal protein
IELDDGJM_00574 1.37e-182 - - - S - - - Phage Mu protein F like protein
IELDDGJM_00576 3.46e-157 yqbD - - L - - - Putative phage serine protease XkdF
IELDDGJM_00577 4.37e-214 xkdG - - S - - - Phage capsid family
IELDDGJM_00578 5.19e-61 - - - S - - - YqbF, hypothetical protein domain
IELDDGJM_00579 2.89e-87 - - - S - - - Protein of unknown function (DUF3199)
IELDDGJM_00580 2.38e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
IELDDGJM_00581 7.57e-114 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
IELDDGJM_00582 8.94e-100 yqbJ - - - - - - -
IELDDGJM_00583 4.2e-35 - - - - - - - -
IELDDGJM_00584 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
IELDDGJM_00585 1.21e-98 xkdM - - S - - - Phage tail tube protein
IELDDGJM_00586 1.27e-89 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
IELDDGJM_00587 0.0 xkdO - - L - - - Transglycosylase SLT domain
IELDDGJM_00588 3.39e-203 xkdO - - L - - - Transglycosylase SLT domain
IELDDGJM_00589 5.17e-153 xkdP - - S - - - Lysin motif
IELDDGJM_00590 1e-222 xkdQ - - G - - - NLP P60 protein
IELDDGJM_00591 1.3e-49 xkdR - - S - - - Protein of unknown function (DUF2577)
IELDDGJM_00592 1.89e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
IELDDGJM_00593 1.64e-239 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IELDDGJM_00594 3.47e-129 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
IELDDGJM_00595 4.11e-52 - - - - - - - -
IELDDGJM_00596 3.97e-281 - - - - - - - -
IELDDGJM_00597 7.37e-67 xkdW - - S - - - XkdW protein
IELDDGJM_00598 1.5e-29 - - - - - - - -
IELDDGJM_00599 8.78e-207 xepA - - - - - - -
IELDDGJM_00600 8.36e-89 - - - S - - - Bacteriophage holin family
IELDDGJM_00601 4.5e-166 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IELDDGJM_00602 5.39e-70 - - - V - - - HNH endonuclease
IELDDGJM_00603 2.55e-90 yokH - - G - - - SMI1 / KNR4 family
IELDDGJM_00604 1.1e-20 - - - S - - - SMI1 / KNR4 family
IELDDGJM_00605 1.19e-38 - - - S - - - SMI1-KNR4 cell-wall
IELDDGJM_00606 3.6e-67 - - - S - - - Immunity protein 50
IELDDGJM_00607 4.22e-130 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
IELDDGJM_00608 3.67e-55 - - - - - - - -
IELDDGJM_00609 2.56e-259 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
IELDDGJM_00610 3.41e-257 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
IELDDGJM_00612 8.53e-96 - - - - - - - -
IELDDGJM_00613 0.0 - - - L - - - response to ionizing radiation
IELDDGJM_00614 9.54e-193 - - - L - - - AAA ATPase domain
IELDDGJM_00615 0.0 - - - L ko:K06400 - ko00000 Recombinase
IELDDGJM_00616 3.66e-284 yfjF - - EGP - - - Belongs to the major facilitator superfamily
IELDDGJM_00617 1.68e-80 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IELDDGJM_00618 4.36e-73 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IELDDGJM_00619 9.81e-47 nucB - - M - - - Deoxyribonuclease NucA/NucB
IELDDGJM_00620 4.28e-167 - - - - - - - -
IELDDGJM_00621 1.94e-244 - - - L - - - ISXO2-like transposase domain
IELDDGJM_00622 5.58e-62 - - - - - - - -
IELDDGJM_00623 1.8e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
IELDDGJM_00624 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
IELDDGJM_00625 1.09e-172 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
IELDDGJM_00626 6.41e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
IELDDGJM_00628 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
IELDDGJM_00629 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IELDDGJM_00630 4.01e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IELDDGJM_00631 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
IELDDGJM_00632 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IELDDGJM_00633 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
IELDDGJM_00634 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IELDDGJM_00635 1.39e-178 yqeM - - Q - - - Methyltransferase
IELDDGJM_00636 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IELDDGJM_00637 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
IELDDGJM_00638 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
IELDDGJM_00639 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
IELDDGJM_00640 2.36e-22 - - - S - - - YqzM-like protein
IELDDGJM_00641 4.06e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
IELDDGJM_00642 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
IELDDGJM_00643 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IELDDGJM_00644 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
IELDDGJM_00645 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
IELDDGJM_00646 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IELDDGJM_00647 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
IELDDGJM_00648 5.74e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IELDDGJM_00649 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IELDDGJM_00650 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
IELDDGJM_00651 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IELDDGJM_00652 1.09e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
IELDDGJM_00653 1.38e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IELDDGJM_00654 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
IELDDGJM_00655 1.81e-232 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IELDDGJM_00656 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
IELDDGJM_00657 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
IELDDGJM_00658 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
IELDDGJM_00659 8.23e-138 ypfA - - M - - - Flagellar protein YcgR
IELDDGJM_00660 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
IELDDGJM_00661 1.84e-194 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
IELDDGJM_00662 7.18e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
IELDDGJM_00663 3.06e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
IELDDGJM_00664 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IELDDGJM_00665 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IELDDGJM_00666 4.15e-186 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
IELDDGJM_00667 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
IELDDGJM_00668 1.74e-142 ypbE - - M - - - Lysin motif
IELDDGJM_00669 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
IELDDGJM_00670 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IELDDGJM_00671 5.44e-256 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
IELDDGJM_00672 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
IELDDGJM_00673 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IELDDGJM_00674 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IELDDGJM_00675 6.53e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IELDDGJM_00676 2e-245 rsiX - - - - - - -
IELDDGJM_00677 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IELDDGJM_00678 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_00679 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IELDDGJM_00680 3.15e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IELDDGJM_00681 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
IELDDGJM_00682 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IELDDGJM_00683 1.81e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IELDDGJM_00684 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
IELDDGJM_00685 2.17e-134 spmA - - S ko:K06373 - ko00000 Spore maturation protein
IELDDGJM_00686 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IELDDGJM_00687 6.13e-128 ypuI - - S - - - Protein of unknown function (DUF3907)
IELDDGJM_00688 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IELDDGJM_00689 4.45e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IELDDGJM_00690 2.41e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
IELDDGJM_00691 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IELDDGJM_00692 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IELDDGJM_00693 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IELDDGJM_00694 1.24e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
IELDDGJM_00695 4e-258 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IELDDGJM_00696 5.98e-72 ypuD - - - - - - -
IELDDGJM_00697 1.54e-121 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IELDDGJM_00699 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
IELDDGJM_00700 2.51e-12 - - - S - - - SNARE associated Golgi protein
IELDDGJM_00702 5.94e-13 - - - M - - - Domain of Unknown Function (DUF1259)
IELDDGJM_00704 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IELDDGJM_00705 3.12e-192 ypuA - - S - - - Secreted protein
IELDDGJM_00706 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IELDDGJM_00707 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
IELDDGJM_00708 7.54e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
IELDDGJM_00709 3.06e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
IELDDGJM_00710 3.48e-245 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
IELDDGJM_00711 1.58e-100 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
IELDDGJM_00712 7.71e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
IELDDGJM_00713 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
IELDDGJM_00714 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IELDDGJM_00715 3.93e-99 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IELDDGJM_00716 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
IELDDGJM_00717 3.37e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IELDDGJM_00718 5.66e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IELDDGJM_00719 6.52e-292 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
IELDDGJM_00720 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
IELDDGJM_00721 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
IELDDGJM_00722 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
IELDDGJM_00723 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IELDDGJM_00724 3.08e-43 yqkK - - - - - - -
IELDDGJM_00725 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IELDDGJM_00726 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IELDDGJM_00727 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
IELDDGJM_00728 1.46e-237 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
IELDDGJM_00729 1.29e-76 ansR - - K - - - Transcriptional regulator
IELDDGJM_00730 4.16e-280 yqxK - - L - - - DNA helicase
IELDDGJM_00731 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
IELDDGJM_00732 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
IELDDGJM_00733 5.13e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
IELDDGJM_00734 2.69e-25 yqkE - - S - - - Protein of unknown function (DUF3886)
IELDDGJM_00735 3.25e-222 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IELDDGJM_00736 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
IELDDGJM_00737 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
IELDDGJM_00738 1.6e-248 yqkA - - K - - - GrpB protein
IELDDGJM_00739 2.63e-77 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
IELDDGJM_00740 2.22e-112 yqjY - - K ko:K06977 - ko00000 acetyltransferase
IELDDGJM_00741 2.66e-65 yqiX - - S - - - YolD-like protein
IELDDGJM_00742 3.45e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IELDDGJM_00744 6.83e-288 yqjV - - G - - - Major Facilitator Superfamily
IELDDGJM_00746 7.43e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IELDDGJM_00747 1.09e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
IELDDGJM_00748 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
IELDDGJM_00749 9.78e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IELDDGJM_00750 1.28e-226 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IELDDGJM_00751 9.98e-183 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IELDDGJM_00752 0.0 rocB - - E - - - arginine degradation protein
IELDDGJM_00753 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IELDDGJM_00754 6.4e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IELDDGJM_00756 9.08e-317 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
IELDDGJM_00757 7.09e-136 yyaP - - H - - - RibD C-terminal domain
IELDDGJM_00758 7.41e-86 - - - S - - - YjbR
IELDDGJM_00759 9.87e-122 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
IELDDGJM_00760 1.55e-125 yyaS - - S ko:K07149 - ko00000 Membrane
IELDDGJM_00761 5.09e-91 yjcF - - S - - - Acetyltransferase (GNAT) domain
IELDDGJM_00762 4.54e-100 yybA - - K - - - transcriptional
IELDDGJM_00763 1.77e-163 - - - S - - - Metallo-beta-lactamase superfamily
IELDDGJM_00764 3.35e-95 yybC - - - - - - -
IELDDGJM_00765 3.1e-101 yjcF - - S - - - Acetyltransferase (GNAT) domain
IELDDGJM_00766 7.57e-210 yybE - - K - - - Transcriptional regulator
IELDDGJM_00767 9.7e-274 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IELDDGJM_00768 1.09e-159 yybG - - S - - - Pentapeptide repeat-containing protein
IELDDGJM_00769 5.02e-87 - - - S - - - SnoaL-like domain
IELDDGJM_00770 3.39e-182 - - - - - - - -
IELDDGJM_00771 4.87e-139 - - - K - - - TipAS antibiotic-recognition domain
IELDDGJM_00772 4.1e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IELDDGJM_00774 4.53e-90 - - - - - - - -
IELDDGJM_00775 2.83e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
IELDDGJM_00776 1.3e-87 yybR - - K - - - Transcriptional regulator
IELDDGJM_00777 6.16e-20 cotF - - M ko:K06329 - ko00000 Spore coat protein
IELDDGJM_00779 1.5e-204 yybS - - S - - - membrane
IELDDGJM_00780 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
IELDDGJM_00781 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IELDDGJM_00782 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IELDDGJM_00783 8.1e-281 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
IELDDGJM_00784 7.73e-22 yycC - - K - - - YycC-like protein
IELDDGJM_00786 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
IELDDGJM_00787 3.17e-97 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IELDDGJM_00788 1.01e-311 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IELDDGJM_00793 3.43e-171 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IELDDGJM_00794 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_00795 0.0 yycH - - S - - - protein conserved in bacteria
IELDDGJM_00796 4.01e-199 yycI - - S - - - protein conserved in bacteria
IELDDGJM_00797 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IELDDGJM_00798 1.01e-273 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IELDDGJM_00799 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IELDDGJM_00800 9.1e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
IELDDGJM_00801 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IELDDGJM_00802 5.33e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IELDDGJM_00804 1.23e-238 - - - S - - - aspartate phosphatase
IELDDGJM_00805 4.89e-108 yycN - - K - - - Acetyltransferase
IELDDGJM_00806 9.3e-167 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IELDDGJM_00807 5.96e-264 yycP - - - - - - -
IELDDGJM_00808 4.53e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
IELDDGJM_00810 1.74e-295 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IELDDGJM_00811 1.64e-89 - - - - - - - -
IELDDGJM_00813 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IELDDGJM_00814 4.45e-156 - - - L - - - Recombinase
IELDDGJM_00815 2.99e-127 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
IELDDGJM_00816 0.0 - - - L - - - DEAD-like helicases superfamily
IELDDGJM_00817 2.66e-262 - - - S - - - Protein of unknown function DUF262
IELDDGJM_00818 2.37e-94 - - - J - - - COG0617 tRNA nucleotidyltransferase poly(A) polymerase
IELDDGJM_00819 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
IELDDGJM_00820 8.12e-17 - - - - - - - -
IELDDGJM_00821 1.35e-237 - - - S - - - Radical SAM superfamily
IELDDGJM_00822 3.65e-172 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
IELDDGJM_00823 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IELDDGJM_00824 9.5e-153 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IELDDGJM_00825 1.19e-23 - - - - - - - -
IELDDGJM_00826 5.21e-164 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_00827 7.55e-44 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
IELDDGJM_00828 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IELDDGJM_00829 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
IELDDGJM_00830 2.68e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
IELDDGJM_00831 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IELDDGJM_00832 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
IELDDGJM_00833 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
IELDDGJM_00834 2.56e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
IELDDGJM_00835 4.71e-263 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
IELDDGJM_00836 1.51e-50 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
IELDDGJM_00837 5.21e-168 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
IELDDGJM_00838 4.06e-149 yxaC - - M - - - effector of murein hydrolase
IELDDGJM_00839 1.46e-77 - - - S ko:K06518 - ko00000,ko02000 LrgA family
IELDDGJM_00840 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IELDDGJM_00841 5.61e-251 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IELDDGJM_00842 9.61e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IELDDGJM_00843 7.9e-246 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
IELDDGJM_00844 1.46e-283 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
IELDDGJM_00845 4.03e-99 yxaI - - S - - - membrane protein domain
IELDDGJM_00846 7.22e-79 - - - S - - - Family of unknown function (DUF5391)
IELDDGJM_00847 1.73e-135 yxaL - - S - - - PQQ-like domain
IELDDGJM_00848 2.09e-16 yxaI - - S - - - membrane protein domain
IELDDGJM_00849 1.14e-311 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IELDDGJM_00850 1.03e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
IELDDGJM_00851 5.9e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IELDDGJM_00853 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
IELDDGJM_00854 2.93e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IELDDGJM_00855 4.13e-62 yxcD - - S - - - Protein of unknown function (DUF2653)
IELDDGJM_00857 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
IELDDGJM_00858 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IELDDGJM_00859 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IELDDGJM_00860 1.46e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IELDDGJM_00861 3.52e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IELDDGJM_00862 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IELDDGJM_00863 4.1e-221 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IELDDGJM_00864 2.32e-295 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
IELDDGJM_00865 1.27e-250 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IELDDGJM_00866 4.4e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
IELDDGJM_00867 2.67e-192 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IELDDGJM_00868 2.83e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IELDDGJM_00869 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IELDDGJM_00870 2.7e-231 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_00871 3.01e-178 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_00872 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IELDDGJM_00873 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
IELDDGJM_00874 7.4e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IELDDGJM_00875 6.79e-91 - - - - - - - -
IELDDGJM_00876 7.57e-28 yxeD - - - - - - -
IELDDGJM_00877 7.32e-42 yxeE - - - - - - -
IELDDGJM_00880 5.69e-194 yxeH - - S - - - hydrolases of the HAD superfamily
IELDDGJM_00881 3.87e-237 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
IELDDGJM_00882 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IELDDGJM_00883 2.99e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IELDDGJM_00884 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IELDDGJM_00885 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IELDDGJM_00886 6.54e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_00887 8.27e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
IELDDGJM_00888 7.39e-310 yxeQ - - S - - - MmgE/PrpD family
IELDDGJM_00889 1.49e-253 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
IELDDGJM_00890 8.39e-194 - - - S - - - Domain of Unknown Function (DUF1206)
IELDDGJM_00891 3.5e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IELDDGJM_00892 1.18e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IELDDGJM_00893 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IELDDGJM_00894 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
IELDDGJM_00895 4.95e-149 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IELDDGJM_00896 4.32e-297 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
IELDDGJM_00897 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IELDDGJM_00898 1.22e-307 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IELDDGJM_00899 2.01e-193 - - - L - - - Protein of unknown function (DUF2726)
IELDDGJM_00900 1.23e-78 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IELDDGJM_00901 0.0 - - - L - - - HKD family nuclease
IELDDGJM_00902 5.38e-37 - - - S - - - Domain of unknown function (DUF5082)
IELDDGJM_00903 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
IELDDGJM_00904 2.21e-271 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
IELDDGJM_00905 8.25e-69 - - - - - - - -
IELDDGJM_00906 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IELDDGJM_00907 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IELDDGJM_00908 9.93e-94 yxiE - - T - - - Belongs to the universal stress protein A family
IELDDGJM_00909 9.38e-180 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
IELDDGJM_00910 8e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IELDDGJM_00911 1.53e-35 - - - - - - - -
IELDDGJM_00912 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IELDDGJM_00913 1.55e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
IELDDGJM_00914 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IELDDGJM_00915 6.07e-211 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
IELDDGJM_00916 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
IELDDGJM_00917 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
IELDDGJM_00918 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
IELDDGJM_00919 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
IELDDGJM_00920 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
IELDDGJM_00921 2.05e-156 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IELDDGJM_00922 6.84e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
IELDDGJM_00923 3.69e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IELDDGJM_00924 3.08e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
IELDDGJM_00925 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
IELDDGJM_00926 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
IELDDGJM_00927 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
IELDDGJM_00928 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
IELDDGJM_00929 5.59e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IELDDGJM_00930 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
IELDDGJM_00931 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
IELDDGJM_00932 5.86e-122 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
IELDDGJM_00933 1.12e-288 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IELDDGJM_00934 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
IELDDGJM_00935 9.81e-200 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
IELDDGJM_00936 3.78e-271 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IELDDGJM_00937 4.93e-210 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
IELDDGJM_00938 6.81e-67 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IELDDGJM_00939 8.27e-163 yebC - - K - - - transcriptional regulatory protein
IELDDGJM_00940 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
IELDDGJM_00941 1.47e-66 - - - S - - - Family of unknown function (DUF5412)
IELDDGJM_00943 2.32e-152 yrzF - - T - - - serine threonine protein kinase
IELDDGJM_00944 2.09e-243 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
IELDDGJM_00945 0.0 csbX - - EGP - - - the major facilitator superfamily
IELDDGJM_00946 1.3e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
IELDDGJM_00947 1.64e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IELDDGJM_00948 3.72e-238 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IELDDGJM_00949 1.75e-31 yrzS - - S - - - Protein of unknown function (DUF2905)
IELDDGJM_00950 2.46e-247 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IELDDGJM_00951 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IELDDGJM_00952 1.24e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
IELDDGJM_00953 1.2e-95 yrzE - - S - - - Protein of unknown function (DUF3792)
IELDDGJM_00954 1.67e-142 yrbG - - S - - - membrane
IELDDGJM_00955 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IELDDGJM_00956 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
IELDDGJM_00957 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IELDDGJM_00958 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IELDDGJM_00959 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
IELDDGJM_00960 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
IELDDGJM_00961 1.46e-117 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IELDDGJM_00962 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IELDDGJM_00963 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IELDDGJM_00964 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
IELDDGJM_00966 4.97e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
IELDDGJM_00967 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IELDDGJM_00968 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IELDDGJM_00969 2.44e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IELDDGJM_00970 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_00971 1.87e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IELDDGJM_00972 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IELDDGJM_00973 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
IELDDGJM_00974 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IELDDGJM_00975 2.29e-104 yrrD - - S - - - protein conserved in bacteria
IELDDGJM_00976 8.4e-42 yrzR - - - - - - -
IELDDGJM_00977 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
IELDDGJM_00978 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IELDDGJM_00979 8.03e-81 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IELDDGJM_00980 2.01e-267 acdA - - I - - - acyl-CoA dehydrogenase
IELDDGJM_00981 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
IELDDGJM_00982 1.82e-275 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IELDDGJM_00983 1.99e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IELDDGJM_00984 1.32e-57 ywjC - - - - - - -
IELDDGJM_00985 1.51e-121 ywjB - - H - - - RibD C-terminal domain
IELDDGJM_00986 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
IELDDGJM_00987 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IELDDGJM_00988 3.42e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
IELDDGJM_00989 7.94e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
IELDDGJM_00990 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
IELDDGJM_00991 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IELDDGJM_00992 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
IELDDGJM_00993 1.06e-178 ywiC - - S - - - YwiC-like protein
IELDDGJM_00994 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
IELDDGJM_00995 6.83e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IELDDGJM_00996 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
IELDDGJM_00997 5.42e-95 ywiB - - S - - - protein conserved in bacteria
IELDDGJM_00998 3.71e-12 - - - S - - - Bacteriocin subtilosin A
IELDDGJM_00999 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
IELDDGJM_01001 2.04e-167 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IELDDGJM_01002 4.86e-297 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
IELDDGJM_01003 2.7e-273 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
IELDDGJM_01004 2.21e-313 - - - L - - - Peptidase, M16
IELDDGJM_01006 8.71e-315 ywhL - - CO - - - amine dehydrogenase activity
IELDDGJM_01007 2.22e-273 ywhK - - CO - - - amine dehydrogenase activity
IELDDGJM_01008 1.32e-106 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IELDDGJM_01010 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IELDDGJM_01011 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IELDDGJM_01012 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IELDDGJM_01013 7.83e-123 ywhD - - S - - - YwhD family
IELDDGJM_01014 3.29e-154 ywhC - - S - - - Peptidase family M50
IELDDGJM_01015 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
IELDDGJM_01016 5.91e-93 ywhA - - K - - - Transcriptional regulator
IELDDGJM_01017 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IELDDGJM_01019 2.13e-297 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
IELDDGJM_01020 3.15e-103 yffB - - K - - - Transcriptional regulator
IELDDGJM_01021 8.53e-115 ywgA - - - ko:K09388 - ko00000 -
IELDDGJM_01022 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
IELDDGJM_01023 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
IELDDGJM_01024 8.85e-142 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
IELDDGJM_01025 4.83e-199 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
IELDDGJM_01026 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IELDDGJM_01027 7.86e-211 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_01028 3.93e-223 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
IELDDGJM_01029 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
IELDDGJM_01030 4.79e-176 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
IELDDGJM_01031 4.12e-292 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
IELDDGJM_01032 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IELDDGJM_01033 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IELDDGJM_01034 6.34e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IELDDGJM_01035 3.76e-98 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IELDDGJM_01036 2.43e-144 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IELDDGJM_01037 2.99e-272 ywfA - - EGP - - - -transporter
IELDDGJM_01038 4.03e-199 yknT - - - ko:K06437 - ko00000 -
IELDDGJM_01039 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IELDDGJM_01040 1.26e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IELDDGJM_01041 5.01e-312 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
IELDDGJM_01042 3.44e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
IELDDGJM_01043 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
IELDDGJM_01044 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IELDDGJM_01045 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IELDDGJM_01046 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IELDDGJM_01047 1.6e-151 yknW - - S - - - Yip1 domain
IELDDGJM_01048 2.72e-232 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IELDDGJM_01049 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_01050 1.48e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IELDDGJM_01051 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_01052 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
IELDDGJM_01053 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IELDDGJM_01054 1.42e-133 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IELDDGJM_01055 7.71e-52 ykoA - - - - - - -
IELDDGJM_01056 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IELDDGJM_01057 1.93e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IELDDGJM_01058 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
IELDDGJM_01059 1.09e-18 - - - S - - - Uncharacterized protein YkpC
IELDDGJM_01060 8.77e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
IELDDGJM_01061 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
IELDDGJM_01062 1.26e-304 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IELDDGJM_01063 1.19e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
IELDDGJM_01064 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IELDDGJM_01065 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IELDDGJM_01066 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IELDDGJM_01067 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
IELDDGJM_01068 5.59e-185 ykrA - - S - - - hydrolases of the HAD superfamily
IELDDGJM_01069 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IELDDGJM_01070 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IELDDGJM_01071 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
IELDDGJM_01072 1.51e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IELDDGJM_01073 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IELDDGJM_01074 9.88e-300 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IELDDGJM_01075 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IELDDGJM_01076 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
IELDDGJM_01078 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
IELDDGJM_01079 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
IELDDGJM_01080 5.28e-152 yktB - - S - - - Belongs to the UPF0637 family
IELDDGJM_01081 4.48e-35 ykzI - - - - - - -
IELDDGJM_01082 3.18e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
IELDDGJM_01083 1.48e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
IELDDGJM_01084 1.37e-218 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IELDDGJM_01085 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
IELDDGJM_01086 0.0 ylaA - - - - - - -
IELDDGJM_01087 6.85e-55 ylaB - - - - - - -
IELDDGJM_01088 1.39e-112 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IELDDGJM_01090 9.96e-57 ylaE - - - - - - -
IELDDGJM_01091 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
IELDDGJM_01092 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
IELDDGJM_01093 4.4e-63 ylaH - - S - - - YlaH-like protein
IELDDGJM_01094 8.92e-44 ylaI - - S - - - protein conserved in bacteria
IELDDGJM_01095 1.64e-124 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IELDDGJM_01096 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
IELDDGJM_01097 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IELDDGJM_01098 1.22e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IELDDGJM_01099 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
IELDDGJM_01100 1.17e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IELDDGJM_01101 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IELDDGJM_01109 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IELDDGJM_01110 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IELDDGJM_01111 6.43e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
IELDDGJM_01112 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
IELDDGJM_01113 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IELDDGJM_01114 1.97e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
IELDDGJM_01115 4.3e-259 cotI - - S ko:K06331 - ko00000 Spore coat protein
IELDDGJM_01116 2.04e-275 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
IELDDGJM_01117 9.85e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
IELDDGJM_01119 8.18e-289 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
IELDDGJM_01120 8.31e-226 ytcB - - M - - - NAD-dependent epimerase dehydratase
IELDDGJM_01121 1.13e-307 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IELDDGJM_01122 6.65e-194 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
IELDDGJM_01123 2.49e-168 yteA - - T - - - COG1734 DnaK suppressor protein
IELDDGJM_01124 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IELDDGJM_01125 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IELDDGJM_01126 1.1e-193 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IELDDGJM_01127 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IELDDGJM_01128 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IELDDGJM_01129 7.07e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IELDDGJM_01130 3.23e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IELDDGJM_01131 1.5e-179 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IELDDGJM_01132 8.31e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IELDDGJM_01133 3.22e-192 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IELDDGJM_01134 9.9e-34 - - - S - - - Domain of Unknown Function (DUF1540)
IELDDGJM_01135 5.47e-237 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IELDDGJM_01136 3e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IELDDGJM_01137 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
IELDDGJM_01138 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IELDDGJM_01139 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IELDDGJM_01140 4.78e-95 ytkA - - S - - - YtkA-like
IELDDGJM_01142 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IELDDGJM_01143 1.52e-79 ytkC - - S - - - Bacteriophage holin family
IELDDGJM_01144 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IELDDGJM_01145 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IELDDGJM_01146 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IELDDGJM_01147 2.66e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IELDDGJM_01148 7.48e-188 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IELDDGJM_01149 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
IELDDGJM_01150 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IELDDGJM_01151 3.07e-284 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IELDDGJM_01152 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IELDDGJM_01153 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IELDDGJM_01154 2.39e-87 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IELDDGJM_01155 6.67e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
IELDDGJM_01156 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
IELDDGJM_01157 3.91e-136 ytqB - - J - - - Putative rRNA methylase
IELDDGJM_01158 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
IELDDGJM_01159 3.64e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
IELDDGJM_01161 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
IELDDGJM_01162 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_01163 3.57e-201 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IELDDGJM_01164 3.4e-186 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
IELDDGJM_01165 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_01166 8.41e-298 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IELDDGJM_01167 9.83e-165 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IELDDGJM_01168 8.4e-235 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
IELDDGJM_01169 3.14e-178 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_01170 1.04e-71 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
IELDDGJM_01171 2.1e-66 - - - Q - - - Collagen triple helix repeat (20 copies)
IELDDGJM_01173 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
IELDDGJM_01174 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
IELDDGJM_01175 1.17e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IELDDGJM_01176 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IELDDGJM_01177 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
IELDDGJM_01178 1.11e-147 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IELDDGJM_01179 2.15e-139 - - - - - - - -
IELDDGJM_01180 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IELDDGJM_01181 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IELDDGJM_01182 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
IELDDGJM_01183 1.2e-30 ymzA - - - - - - -
IELDDGJM_01184 1.63e-31 - - - - - - - -
IELDDGJM_01185 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IELDDGJM_01186 5.61e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IELDDGJM_01187 7.68e-76 ymaF - - S - - - YmaF family
IELDDGJM_01189 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IELDDGJM_01190 6.39e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
IELDDGJM_01191 2.44e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
IELDDGJM_01192 3.96e-163 ymaC - - S - - - Replication protein
IELDDGJM_01194 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
IELDDGJM_01195 1.8e-205 - - - S - - - Metallo-beta-lactamase superfamily
IELDDGJM_01196 8.03e-81 ymzB - - - - - - -
IELDDGJM_01197 4.14e-134 pksA - - K - - - Transcriptional regulator
IELDDGJM_01198 5.38e-125 ymcC - - S - - - Membrane
IELDDGJM_01199 6.4e-90 - - - S - - - Regulatory protein YrvL
IELDDGJM_01200 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IELDDGJM_01201 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IELDDGJM_01202 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
IELDDGJM_01203 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
IELDDGJM_01204 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IELDDGJM_01205 3.81e-274 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IELDDGJM_01206 3.38e-252 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IELDDGJM_01207 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
IELDDGJM_01208 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
IELDDGJM_01209 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
IELDDGJM_01210 4.67e-279 pbpX - - V - - - Beta-lactamase
IELDDGJM_01211 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IELDDGJM_01212 3.56e-298 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
IELDDGJM_01213 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IELDDGJM_01214 9.3e-172 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
IELDDGJM_01215 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
IELDDGJM_01216 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
IELDDGJM_01217 1.05e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IELDDGJM_01218 2.37e-309 ymfH - - S - - - zinc protease
IELDDGJM_01219 3.17e-297 albE - - S - - - Peptidase M16
IELDDGJM_01220 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IELDDGJM_01221 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_01222 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IELDDGJM_01223 4.94e-44 - - - S - - - YlzJ-like protein
IELDDGJM_01224 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
IELDDGJM_01225 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IELDDGJM_01226 6.39e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IELDDGJM_01227 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IELDDGJM_01228 2.36e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IELDDGJM_01229 1.16e-140 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IELDDGJM_01230 1.52e-207 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
IELDDGJM_01231 1.53e-56 ymxH - - S - - - YlmC YmxH family
IELDDGJM_01232 9.36e-295 mlpA - - S - - - Belongs to the peptidase M16 family
IELDDGJM_01233 1.45e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
IELDDGJM_01234 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IELDDGJM_01235 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IELDDGJM_01236 9.42e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
IELDDGJM_01237 4.08e-218 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IELDDGJM_01238 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IELDDGJM_01239 1.58e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
IELDDGJM_01240 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IELDDGJM_01241 6.16e-63 ylxQ - - J - - - ribosomal protein
IELDDGJM_01242 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
IELDDGJM_01243 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
IELDDGJM_01244 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
IELDDGJM_01245 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IELDDGJM_01246 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IELDDGJM_01247 4.72e-285 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
IELDDGJM_01248 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IELDDGJM_01249 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
IELDDGJM_01250 5.46e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IELDDGJM_01251 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IELDDGJM_01252 1.18e-162 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
IELDDGJM_01253 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IELDDGJM_01254 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
IELDDGJM_01255 6.91e-101 ylxL - - - - - - -
IELDDGJM_01256 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IELDDGJM_01257 5.54e-111 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IELDDGJM_01258 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IELDDGJM_01259 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
IELDDGJM_01260 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
IELDDGJM_01261 2.58e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IELDDGJM_01262 1.49e-198 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
IELDDGJM_01263 1.62e-255 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
IELDDGJM_01264 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IELDDGJM_01265 1.3e-242 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IELDDGJM_01266 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
IELDDGJM_01267 1.06e-49 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
IELDDGJM_01268 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
IELDDGJM_01269 1.3e-135 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
IELDDGJM_01270 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
IELDDGJM_01271 1.6e-252 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IELDDGJM_01272 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IELDDGJM_01273 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
IELDDGJM_01274 2.86e-175 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
IELDDGJM_01275 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
IELDDGJM_01276 2.21e-312 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
IELDDGJM_01277 2.93e-83 ylxF - - S - - - MgtE intracellular N domain
IELDDGJM_01278 1.03e-90 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
IELDDGJM_01279 1.22e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IELDDGJM_01280 1.11e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
IELDDGJM_01281 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IELDDGJM_01282 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
IELDDGJM_01283 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
IELDDGJM_01284 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
IELDDGJM_01285 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IELDDGJM_01286 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IELDDGJM_01287 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IELDDGJM_01288 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IELDDGJM_01289 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
IELDDGJM_01290 4.47e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IELDDGJM_01291 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IELDDGJM_01292 2.1e-214 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
IELDDGJM_01293 6.23e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IELDDGJM_01294 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IELDDGJM_01295 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
IELDDGJM_01296 0.0 ylqG - - - - - - -
IELDDGJM_01297 3.94e-173 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IELDDGJM_01298 1.4e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IELDDGJM_01299 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IELDDGJM_01300 1.39e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
IELDDGJM_01301 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IELDDGJM_01302 9.77e-80 ylqD - - S - - - YlqD protein
IELDDGJM_01303 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
IELDDGJM_01304 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
IELDDGJM_01305 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IELDDGJM_01306 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IELDDGJM_01307 1.34e-160 - - - S - - - Phosphotransferase enzyme family
IELDDGJM_01308 2.28e-225 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IELDDGJM_01309 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
IELDDGJM_01310 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IELDDGJM_01311 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IELDDGJM_01312 5.81e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IELDDGJM_01313 3.09e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IELDDGJM_01314 3.96e-228 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IELDDGJM_01315 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IELDDGJM_01316 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IELDDGJM_01317 9.75e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IELDDGJM_01318 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IELDDGJM_01319 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
IELDDGJM_01320 3.65e-78 yloU - - S - - - protein conserved in bacteria
IELDDGJM_01321 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
IELDDGJM_01322 4.7e-156 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
IELDDGJM_01323 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
IELDDGJM_01324 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IELDDGJM_01325 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
IELDDGJM_01326 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
IELDDGJM_01327 5.3e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IELDDGJM_01328 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IELDDGJM_01329 1.74e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IELDDGJM_01330 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IELDDGJM_01331 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IELDDGJM_01332 7.28e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IELDDGJM_01333 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IELDDGJM_01334 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
IELDDGJM_01335 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
IELDDGJM_01336 8.41e-202 yloC - - S - - - stress-induced protein
IELDDGJM_01337 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
IELDDGJM_01338 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
IELDDGJM_01339 3.78e-107 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
IELDDGJM_01340 3.41e-186 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
IELDDGJM_01341 8.38e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IELDDGJM_01342 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
IELDDGJM_01343 1.35e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
IELDDGJM_01344 1.21e-228 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
IELDDGJM_01345 4.89e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
IELDDGJM_01346 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IELDDGJM_01347 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IELDDGJM_01348 7.36e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IELDDGJM_01349 7.44e-183 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IELDDGJM_01350 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
IELDDGJM_01351 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IELDDGJM_01352 9.71e-317 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IELDDGJM_01353 1.04e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
IELDDGJM_01354 1.3e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
IELDDGJM_01355 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IELDDGJM_01356 2.38e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IELDDGJM_01357 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IELDDGJM_01358 1.3e-82 ylyA - - T - - - COG1734 DnaK suppressor protein
IELDDGJM_01359 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IELDDGJM_01360 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
IELDDGJM_01361 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
IELDDGJM_01362 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
IELDDGJM_01363 1.28e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IELDDGJM_01364 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IELDDGJM_01365 7.53e-203 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
IELDDGJM_01366 1.03e-50 ylmC - - S - - - sporulation protein
IELDDGJM_01367 2.68e-314 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
IELDDGJM_01368 1.57e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IELDDGJM_01369 1.09e-177 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IELDDGJM_01370 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IELDDGJM_01371 8.58e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IELDDGJM_01373 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
IELDDGJM_01374 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
IELDDGJM_01375 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IELDDGJM_01376 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IELDDGJM_01377 1.54e-75 sbp - - S - - - small basic protein
IELDDGJM_01378 7.41e-151 ylxX - - S - - - protein conserved in bacteria
IELDDGJM_01379 6.39e-142 ylxW - - S - - - protein conserved in bacteria
IELDDGJM_01380 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IELDDGJM_01381 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
IELDDGJM_01382 9.03e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IELDDGJM_01383 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IELDDGJM_01384 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IELDDGJM_01385 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IELDDGJM_01386 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IELDDGJM_01387 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
IELDDGJM_01388 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IELDDGJM_01389 3.42e-68 ftsL - - D - - - Essential cell division protein
IELDDGJM_01390 4.76e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IELDDGJM_01391 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
IELDDGJM_01392 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IELDDGJM_01393 3.6e-211 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IELDDGJM_01394 1.33e-115 ylbP - - K - - - n-acetyltransferase
IELDDGJM_01395 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IELDDGJM_01396 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
IELDDGJM_01397 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
IELDDGJM_01399 1.95e-290 ylbM - - S - - - Belongs to the UPF0348 family
IELDDGJM_01400 2.24e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
IELDDGJM_01401 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IELDDGJM_01402 5.27e-280 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
IELDDGJM_01403 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IELDDGJM_01404 4.99e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
IELDDGJM_01405 4.36e-52 ylbG - - S - - - UPF0298 protein
IELDDGJM_01406 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
IELDDGJM_01407 1.73e-48 ylbE - - S - - - YlbE-like protein
IELDDGJM_01408 3.24e-89 ylbD - - S - - - Putative coat protein
IELDDGJM_01409 2.18e-256 ylbC - - S - - - protein with SCP PR1 domains
IELDDGJM_01410 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
IELDDGJM_01411 1.88e-80 ylbA - - S - - - YugN-like family
IELDDGJM_01412 9.56e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
IELDDGJM_01413 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IELDDGJM_01414 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IELDDGJM_01415 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IELDDGJM_01416 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IELDDGJM_01417 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IELDDGJM_01418 2.44e-213 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IELDDGJM_01419 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
IELDDGJM_01420 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
IELDDGJM_01421 3.15e-256 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IELDDGJM_01422 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
IELDDGJM_01423 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IELDDGJM_01424 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IELDDGJM_01425 2.11e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
IELDDGJM_01426 7.42e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IELDDGJM_01427 2.59e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IELDDGJM_01428 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IELDDGJM_01429 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
IELDDGJM_01430 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IELDDGJM_01431 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IELDDGJM_01432 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IELDDGJM_01433 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
IELDDGJM_01434 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
IELDDGJM_01435 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IELDDGJM_01436 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IELDDGJM_01437 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IELDDGJM_01438 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IELDDGJM_01439 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IELDDGJM_01440 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IELDDGJM_01441 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
IELDDGJM_01442 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IELDDGJM_01443 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IELDDGJM_01444 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
IELDDGJM_01445 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IELDDGJM_01446 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IELDDGJM_01447 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IELDDGJM_01448 1.36e-285 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IELDDGJM_01449 8.42e-236 ybaC - - S - - - Alpha/beta hydrolase family
IELDDGJM_01450 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
IELDDGJM_01451 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IELDDGJM_01452 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
IELDDGJM_01453 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IELDDGJM_01454 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IELDDGJM_01455 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IELDDGJM_01456 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IELDDGJM_01457 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IELDDGJM_01458 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IELDDGJM_01459 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
IELDDGJM_01460 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IELDDGJM_01461 7.32e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IELDDGJM_01462 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IELDDGJM_01463 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IELDDGJM_01464 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IELDDGJM_01465 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IELDDGJM_01466 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IELDDGJM_01467 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IELDDGJM_01468 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IELDDGJM_01469 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
IELDDGJM_01470 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IELDDGJM_01471 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IELDDGJM_01472 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IELDDGJM_01473 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IELDDGJM_01474 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IELDDGJM_01475 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
IELDDGJM_01476 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IELDDGJM_01477 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IELDDGJM_01478 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IELDDGJM_01479 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
IELDDGJM_01480 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IELDDGJM_01481 2.69e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IELDDGJM_01482 4.39e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IELDDGJM_01483 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IELDDGJM_01484 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IELDDGJM_01485 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
IELDDGJM_01486 7.18e-185 ybaJ - - Q - - - Methyltransferase domain
IELDDGJM_01487 1.53e-92 ybaK - - S - - - Protein of unknown function (DUF2521)
IELDDGJM_01488 3.03e-168 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IELDDGJM_01489 9.01e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IELDDGJM_01490 1.04e-122 gerD - - - ko:K06294 - ko00000 -
IELDDGJM_01491 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
IELDDGJM_01492 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
IELDDGJM_01493 6.25e-213 - - - K - - - AraC-like ligand binding domain
IELDDGJM_01494 6.19e-93 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IELDDGJM_01495 6.73e-110 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IELDDGJM_01496 3.08e-208 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
IELDDGJM_01497 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IELDDGJM_01498 1.27e-275 ydeG - - EGP - - - Major facilitator superfamily
IELDDGJM_01499 9.2e-70 ydeH - - - - - - -
IELDDGJM_01500 4.05e-135 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
IELDDGJM_01501 8.21e-139 - - - - - - - -
IELDDGJM_01502 2.4e-41 - - - S - - - SNARE associated Golgi protein
IELDDGJM_01503 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
IELDDGJM_01504 4.22e-111 - - - K - - - Transcriptional regulator C-terminal region
IELDDGJM_01505 1.23e-124 ydeK - - EG - - - -transporter
IELDDGJM_01506 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IELDDGJM_01507 1.5e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
IELDDGJM_01508 4.98e-137 - - - S ko:K07002 - ko00000 Serine hydrolase
IELDDGJM_01509 5.22e-75 - - - K - - - HxlR-like helix-turn-helix
IELDDGJM_01510 1.96e-195 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IELDDGJM_01511 1.05e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
IELDDGJM_01512 3.38e-292 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IELDDGJM_01513 6.35e-188 - - - J - - - GNAT acetyltransferase
IELDDGJM_01514 2.3e-202 - - - EG - - - EamA-like transporter family
IELDDGJM_01515 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IELDDGJM_01516 6.7e-148 ydfE - - S - - - Flavin reductase like domain
IELDDGJM_01517 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IELDDGJM_01518 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IELDDGJM_01520 3.43e-232 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_01521 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
IELDDGJM_01522 3.77e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
IELDDGJM_01523 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
IELDDGJM_01525 3.65e-13 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
IELDDGJM_01529 3.36e-75 - - - L - - - COG3666 Transposase and inactivated derivatives
IELDDGJM_01530 8.64e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IELDDGJM_01531 7.48e-140 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
IELDDGJM_01532 7.49e-236 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IELDDGJM_01533 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
IELDDGJM_01534 3.78e-74 ydfQ - - CO - - - Thioredoxin
IELDDGJM_01535 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
IELDDGJM_01536 5.33e-39 - - - - - - - -
IELDDGJM_01538 4.33e-34 ydfR - - S - - - Protein of unknown function (DUF421)
IELDDGJM_01539 4.9e-36 ydfR - - S - - - Protein of unknown function (DUF421)
IELDDGJM_01540 5.32e-25 ydfS - - S - - - Protein of unknown function (DUF421)
IELDDGJM_01541 4.32e-94 ydfS - - S - - - Protein of unknown function (DUF421)
IELDDGJM_01542 1.28e-98 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IELDDGJM_01543 5.54e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
IELDDGJM_01544 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
IELDDGJM_01545 8.51e-128 ydgC - - K - - - Bacterial regulatory proteins, tetR family
IELDDGJM_01546 3.2e-67 - - - S - - - DoxX-like family
IELDDGJM_01547 1.97e-111 yycN - - K - - - Acetyltransferase
IELDDGJM_01548 1.18e-239 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
IELDDGJM_01549 2.5e-122 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
IELDDGJM_01550 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IELDDGJM_01551 5.94e-118 - - - S - - - DinB family
IELDDGJM_01552 1.45e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IELDDGJM_01553 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
IELDDGJM_01554 6.42e-147 ydgI - - C - - - nitroreductase
IELDDGJM_01555 1.9e-89 - - - K - - - Winged helix DNA-binding domain
IELDDGJM_01556 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
IELDDGJM_01557 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
IELDDGJM_01558 5.24e-158 ydhC - - K - - - FCD
IELDDGJM_01559 2.01e-306 ydhD - - M - - - Glycosyl hydrolase
IELDDGJM_01560 2.35e-295 - - - M - - - nucleic acid phosphodiester bond hydrolysis
IELDDGJM_01562 3.8e-50 - - - - - - - -
IELDDGJM_01565 6.25e-270 yjcL - - S - - - Protein of unknown function (DUF819)
IELDDGJM_01566 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
IELDDGJM_01567 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IELDDGJM_01568 1.14e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IELDDGJM_01569 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
IELDDGJM_01570 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
IELDDGJM_01571 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IELDDGJM_01572 6.31e-51 - - - - - - - -
IELDDGJM_01573 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IELDDGJM_01574 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
IELDDGJM_01577 5.03e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
IELDDGJM_01578 1.44e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
IELDDGJM_01579 2.34e-51 cotW - - - ko:K06341 - ko00000 -
IELDDGJM_01580 2.06e-109 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
IELDDGJM_01581 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
IELDDGJM_01582 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
IELDDGJM_01583 3.11e-98 yjbX - - S - - - Spore coat protein
IELDDGJM_01584 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
IELDDGJM_01585 3.98e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IELDDGJM_01586 2.52e-237 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IELDDGJM_01587 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IELDDGJM_01588 3.1e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
IELDDGJM_01589 1.09e-275 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
IELDDGJM_01590 5.47e-137 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
IELDDGJM_01591 4.69e-176 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IELDDGJM_01592 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IELDDGJM_01593 2.71e-179 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IELDDGJM_01594 9.01e-204 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IELDDGJM_01595 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IELDDGJM_01596 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
IELDDGJM_01597 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
IELDDGJM_01598 7.32e-130 yjbK - - S - - - protein conserved in bacteria
IELDDGJM_01599 1.46e-128 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IELDDGJM_01600 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
IELDDGJM_01601 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IELDDGJM_01603 2.68e-28 - - - - - - - -
IELDDGJM_01604 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
IELDDGJM_01605 4.2e-280 coiA - - S ko:K06198 - ko00000 Competence protein
IELDDGJM_01606 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IELDDGJM_01607 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
IELDDGJM_01608 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IELDDGJM_01609 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IELDDGJM_01610 3.06e-256 yjbB - - EGP - - - Major Facilitator Superfamily
IELDDGJM_01611 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IELDDGJM_01612 3.92e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IELDDGJM_01613 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IELDDGJM_01614 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IELDDGJM_01615 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IELDDGJM_01616 5.06e-234 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
IELDDGJM_01617 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
IELDDGJM_01618 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IELDDGJM_01619 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IELDDGJM_01620 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
IELDDGJM_01621 6.64e-234 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IELDDGJM_01622 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IELDDGJM_01623 2.61e-190 yjaZ - - O - - - Zn-dependent protease
IELDDGJM_01624 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IELDDGJM_01625 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IELDDGJM_01626 2.67e-38 yjzB - - - - - - -
IELDDGJM_01627 8.39e-265 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IELDDGJM_01628 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
IELDDGJM_01629 5.47e-178 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
IELDDGJM_01630 3.62e-287 - - - EGP - - - Major Facilitator Superfamily
IELDDGJM_01631 2.19e-124 - - - S - - - YcxB-like protein
IELDDGJM_01632 9.36e-205 ycxC - - EG - - - EamA-like transporter family
IELDDGJM_01633 3.74e-316 ycxD - - K - - - GntR family transcriptional regulator
IELDDGJM_01634 3.91e-144 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
IELDDGJM_01635 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
IELDDGJM_01636 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IELDDGJM_01637 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IELDDGJM_01638 4.3e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
IELDDGJM_01639 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
IELDDGJM_01640 7.5e-139 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IELDDGJM_01641 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IELDDGJM_01642 2.33e-51 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
IELDDGJM_01643 2.15e-53 yclD - - - - - - -
IELDDGJM_01644 1.11e-201 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
IELDDGJM_01645 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
IELDDGJM_01646 0.0 yclG - - M - - - Pectate lyase superfamily protein
IELDDGJM_01648 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
IELDDGJM_01649 2.36e-287 gerKC - - S ko:K06297 - ko00000 spore germination
IELDDGJM_01650 8.19e-248 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
IELDDGJM_01651 4.82e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IELDDGJM_01652 2.52e-276 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
IELDDGJM_01653 2.09e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IELDDGJM_01654 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IELDDGJM_01655 3.09e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IELDDGJM_01657 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IELDDGJM_01658 1e-305 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IELDDGJM_01659 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IELDDGJM_01660 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IELDDGJM_01661 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_01662 1.91e-211 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
IELDDGJM_01663 0.0 ycnB - - EGP - - - the major facilitator superfamily
IELDDGJM_01664 5.87e-198 ycnC - - K - - - Transcriptional regulator
IELDDGJM_01665 2.48e-173 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IELDDGJM_01666 1.68e-60 ycnE - - S - - - Monooxygenase
IELDDGJM_01667 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IELDDGJM_01668 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IELDDGJM_01669 3.26e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IELDDGJM_01670 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IELDDGJM_01671 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
IELDDGJM_01672 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IELDDGJM_01673 1.34e-132 ycnI - - S - - - protein conserved in bacteria
IELDDGJM_01674 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
IELDDGJM_01675 2.03e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IELDDGJM_01676 4.67e-75 - - - - - - - -
IELDDGJM_01677 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
IELDDGJM_01678 4.81e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IELDDGJM_01679 1.21e-265 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
IELDDGJM_01680 5.86e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
IELDDGJM_01682 9.86e-94 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IELDDGJM_01683 6.98e-143 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
IELDDGJM_01684 1.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
IELDDGJM_01685 3.59e-203 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
IELDDGJM_01686 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
IELDDGJM_01687 7.71e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IELDDGJM_01688 4.86e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IELDDGJM_01689 7.78e-33 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IELDDGJM_01690 1.41e-115 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IELDDGJM_01691 6.32e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
IELDDGJM_01692 5.01e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
IELDDGJM_01693 2.88e-111 yxjI - - S - - - LURP-one-related
IELDDGJM_01696 1.5e-296 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
IELDDGJM_01697 3.67e-146 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
IELDDGJM_01698 7.75e-240 - - - T - - - Signal transduction histidine kinase
IELDDGJM_01699 6.58e-101 - - - S - - - Protein of unknown function (DUF1453)
IELDDGJM_01700 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IELDDGJM_01701 2.03e-99 yxkC - - S - - - Domain of unknown function (DUF4352)
IELDDGJM_01702 2.67e-187 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IELDDGJM_01703 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IELDDGJM_01704 5.93e-205 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
IELDDGJM_01705 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IELDDGJM_01706 1.3e-199 yxkH - - G - - - Polysaccharide deacetylase
IELDDGJM_01708 0.0 - - - O - - - Peptidase family M48
IELDDGJM_01709 3.8e-308 cimH - - C - - - COG3493 Na citrate symporter
IELDDGJM_01710 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IELDDGJM_01711 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
IELDDGJM_01712 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
IELDDGJM_01713 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
IELDDGJM_01714 4.18e-199 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IELDDGJM_01715 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
IELDDGJM_01716 3.69e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IELDDGJM_01717 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
IELDDGJM_01718 1.15e-39 - - - - - - - -
IELDDGJM_01719 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
IELDDGJM_01720 1.17e-188 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_01721 4.92e-125 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IELDDGJM_01722 4.7e-268 yxlH - - EGP - - - Major Facilitator Superfamily
IELDDGJM_01723 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IELDDGJM_01724 1.54e-143 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
IELDDGJM_01725 8.94e-28 yxzF - - - - - - -
IELDDGJM_01726 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
IELDDGJM_01727 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
IELDDGJM_01728 1.75e-313 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IELDDGJM_01729 1.3e-49 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IELDDGJM_01730 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IELDDGJM_01731 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IELDDGJM_01732 3.02e-82 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IELDDGJM_01733 1.5e-60 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IELDDGJM_01734 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IELDDGJM_01735 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IELDDGJM_01736 9.34e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
IELDDGJM_01737 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IELDDGJM_01739 5.95e-212 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
IELDDGJM_01740 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
IELDDGJM_01741 3.96e-165 - - - EGP - - - Permeases of the major facilitator superfamily
IELDDGJM_01742 5.58e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
IELDDGJM_01743 5.37e-116 - - - K - - - Helix-turn-helix XRE-family like proteins
IELDDGJM_01744 6.76e-137 yfhC - - C - - - nitroreductase
IELDDGJM_01745 2.85e-210 yfhB - - S - - - PhzF family
IELDDGJM_01746 3.49e-227 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IELDDGJM_01747 1.04e-223 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IELDDGJM_01748 9.03e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IELDDGJM_01749 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IELDDGJM_01750 2.11e-103 yfiV - - K - - - transcriptional
IELDDGJM_01751 0.0 yfiU - - EGP - - - the major facilitator superfamily
IELDDGJM_01752 2.31e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
IELDDGJM_01753 4.25e-249 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IELDDGJM_01754 3.07e-51 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
IELDDGJM_01755 7.19e-24 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
IELDDGJM_01756 1.89e-128 padR - - K - - - transcriptional
IELDDGJM_01757 7.31e-86 - - - J - - - Acetyltransferase (GNAT) domain
IELDDGJM_01758 1.01e-254 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IELDDGJM_01759 3.66e-258 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IELDDGJM_01760 6.48e-216 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_01761 6.07e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
IELDDGJM_01762 2.94e-273 baeS - - T - - - Histidine kinase
IELDDGJM_01764 6.76e-291 - - - S - - - Oxidoreductase
IELDDGJM_01765 2.23e-233 - - - G - - - Xylose isomerase
IELDDGJM_01766 0.0 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IELDDGJM_01767 5.61e-223 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
IELDDGJM_01768 2.97e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
IELDDGJM_01769 3.34e-83 yfiD3 - - S - - - DoxX
IELDDGJM_01770 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IELDDGJM_01771 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
IELDDGJM_01772 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IELDDGJM_01773 2.05e-179 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
IELDDGJM_01774 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IELDDGJM_01775 9.28e-60 yfjA - - S - - - Belongs to the WXG100 family
IELDDGJM_01776 6.91e-241 yfjB - - - - - - -
IELDDGJM_01777 1.19e-160 yfjC - - - - - - -
IELDDGJM_01778 6.64e-110 - - - S - - - Family of unknown function (DUF5381)
IELDDGJM_01779 1.23e-73 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
IELDDGJM_01780 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
IELDDGJM_01781 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
IELDDGJM_01782 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IELDDGJM_01783 3.29e-262 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IELDDGJM_01784 4.56e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IELDDGJM_01785 6.48e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IELDDGJM_01787 7.85e-110 yfjM - - S - - - Psort location Cytoplasmic, score
IELDDGJM_01788 5.07e-236 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IELDDGJM_01789 4.32e-59 - - - S - - - YfzA-like protein
IELDDGJM_01790 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IELDDGJM_01791 2.76e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IELDDGJM_01792 1.84e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
IELDDGJM_01793 1.13e-192 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IELDDGJM_01794 2.43e-196 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
IELDDGJM_01795 3.26e-36 yfjT - - - - - - -
IELDDGJM_01796 1.76e-283 yfkA - - S - - - YfkB-like domain
IELDDGJM_01797 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
IELDDGJM_01798 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
IELDDGJM_01799 9.02e-131 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IELDDGJM_01800 2.92e-259 yaaN - - P - - - Belongs to the TelA family
IELDDGJM_01801 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
IELDDGJM_01802 1.63e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IELDDGJM_01803 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
IELDDGJM_01804 1.8e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
IELDDGJM_01805 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IELDDGJM_01806 5.2e-188 yaaT - - S - - - stage 0 sporulation protein
IELDDGJM_01807 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
IELDDGJM_01808 4.66e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
IELDDGJM_01809 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
IELDDGJM_01810 7.26e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IELDDGJM_01811 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
IELDDGJM_01812 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IELDDGJM_01813 1.98e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
IELDDGJM_01814 1.67e-277 yabE - - T - - - protein conserved in bacteria
IELDDGJM_01815 4.09e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IELDDGJM_01816 1.05e-195 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IELDDGJM_01817 2.39e-193 yabG - - S ko:K06436 - ko00000 peptidase
IELDDGJM_01818 5.32e-53 veg - - S - - - protein conserved in bacteria
IELDDGJM_01819 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
IELDDGJM_01820 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IELDDGJM_01821 3.82e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
IELDDGJM_01822 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
IELDDGJM_01823 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IELDDGJM_01824 4.27e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IELDDGJM_01825 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IELDDGJM_01826 1.69e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IELDDGJM_01827 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IELDDGJM_01828 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
IELDDGJM_01829 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IELDDGJM_01830 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
IELDDGJM_01831 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IELDDGJM_01832 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IELDDGJM_01833 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IELDDGJM_01834 1.91e-66 yabP - - S - - - Sporulation protein YabP
IELDDGJM_01835 2.58e-138 yabQ - - S - - - spore cortex biosynthesis protein
IELDDGJM_01836 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
IELDDGJM_01837 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IELDDGJM_01840 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
IELDDGJM_01841 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IELDDGJM_01842 1.4e-235 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
IELDDGJM_01843 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IELDDGJM_01844 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
IELDDGJM_01845 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IELDDGJM_01846 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IELDDGJM_01847 7.84e-207 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IELDDGJM_01848 9.83e-204 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
IELDDGJM_01849 3.62e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IELDDGJM_01850 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IELDDGJM_01851 5.98e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
IELDDGJM_01852 5.36e-215 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
IELDDGJM_01853 2.62e-202 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IELDDGJM_01854 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IELDDGJM_01855 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IELDDGJM_01856 1.81e-41 yazB - - K - - - transcriptional
IELDDGJM_01857 4.56e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IELDDGJM_01858 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
IELDDGJM_01859 4.44e-205 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
IELDDGJM_01860 7.29e-84 ydjM - - M - - - Lytic transglycolase
IELDDGJM_01861 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
IELDDGJM_01862 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IELDDGJM_01863 1.91e-33 - - - S - - - Ion transport 2 domain protein
IELDDGJM_01864 4.11e-183 - - - S - - - Ion transport 2 domain protein
IELDDGJM_01865 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
IELDDGJM_01866 1.94e-168 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
IELDDGJM_01867 2.11e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IELDDGJM_01868 2.54e-146 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
IELDDGJM_01869 1.3e-215 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
IELDDGJM_01870 7.18e-315 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
IELDDGJM_01871 5.04e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
IELDDGJM_01872 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
IELDDGJM_01873 3.95e-101 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
IELDDGJM_01874 2.99e-39 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
IELDDGJM_01875 8.92e-52 - - - - - - - -
IELDDGJM_01876 1.05e-71 - - - - - - - -
IELDDGJM_01878 1.48e-73 - - - - - - - -
IELDDGJM_01881 4.06e-79 - - - K - - - Protein of unknown function (DUF4065)
IELDDGJM_01882 4.41e-09 - - - S - - - Motility quorum-sensing regulator, toxin of MqsA
IELDDGJM_01883 4.75e-38 - - - K - - - Helix-turn-helix domain
IELDDGJM_01886 3.05e-54 - - - S - - - protein domain associated with
IELDDGJM_01887 9.41e-139 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IELDDGJM_01888 1.58e-41 xhlB - - S - - - SPP1 phage holin
IELDDGJM_01889 7.72e-37 xhlA - - S - - - Haemolysin XhlA
IELDDGJM_01894 2.76e-219 - - - L - - - Phage minor structural protein
IELDDGJM_01895 6.65e-40 - - - S - - - Phage tail protein
IELDDGJM_01896 5.11e-145 - - - D - - - minor tail protein
IELDDGJM_01897 8.86e-46 - - - S - - - Bacteriophage Gp15 protein
IELDDGJM_01899 3.38e-53 - - - N - - - Belongs to the glycosyl hydrolase family 6
IELDDGJM_01901 7.09e-28 - - - S - - - Minor capsid protein
IELDDGJM_01903 2.32e-27 - - - - - - - -
IELDDGJM_01904 3.89e-10 chiA - - G - - - Belongs to the glycosyl hydrolase 18 family
IELDDGJM_01905 1.16e-123 - - - - - - - -
IELDDGJM_01906 9.91e-25 - - - - - - - -
IELDDGJM_01907 4.03e-116 - - - M - - - Phage minor capsid protein 2
IELDDGJM_01908 1.16e-210 - - - S - - - portal protein
IELDDGJM_01909 8.71e-255 - - - S ko:K06909 - ko00000 Terminase RNAseH like domain
IELDDGJM_01910 2.29e-118 yqaS - - L - - - DNA packaging
IELDDGJM_01912 1.77e-103 - - - L - - - Transposase
IELDDGJM_01919 0.000179 - - - S - - - YopX protein
IELDDGJM_01920 4.55e-77 - - - - - - - -
IELDDGJM_01921 1.03e-92 - - - - - - - -
IELDDGJM_01923 1.27e-97 - - - - - - - -
IELDDGJM_01925 8.51e-26 yqaO - - S - - - Phage-like element PBSX protein XtrA
IELDDGJM_01927 3.16e-71 - - - S - - - Protein of unknown function (DUF1064)
IELDDGJM_01928 1.53e-20 - - - S - - - YopX protein
IELDDGJM_01930 6.06e-102 yqaM - - L - - - IstB-like ATP binding protein
IELDDGJM_01931 2.85e-97 yqaL - - L - - - DnaD domain protein
IELDDGJM_01932 1.79e-171 recT - - L ko:K07455 - ko00000,ko03400 RecT family
IELDDGJM_01933 1.33e-193 yqaJ - - L - - - YqaJ-like viral recombinase domain
IELDDGJM_01935 1.2e-49 yraG - - - ko:K06440 - ko00000 -
IELDDGJM_01936 7.14e-74 yraF - - M - - - Spore coat protein
IELDDGJM_01937 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IELDDGJM_01938 6.11e-36 yraE - - - ko:K06440 - ko00000 -
IELDDGJM_01939 1.41e-63 yraD - - M ko:K06439 - ko00000 Spore coat protein
IELDDGJM_01940 2.32e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
IELDDGJM_01941 2.83e-30 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
IELDDGJM_01942 4.24e-199 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
IELDDGJM_01943 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IELDDGJM_01944 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IELDDGJM_01945 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
IELDDGJM_01946 1.75e-167 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
IELDDGJM_01947 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
IELDDGJM_01948 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
IELDDGJM_01949 0.0 levR - - K - - - PTS system fructose IIA component
IELDDGJM_01950 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IELDDGJM_01951 1.88e-135 yrhP - - E - - - LysE type translocator
IELDDGJM_01952 5.9e-194 yrhO - - K - - - Archaeal transcriptional regulator TrmB
IELDDGJM_01953 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IELDDGJM_01954 7.09e-191 rsiV - - S - - - Protein of unknown function (DUF3298)
IELDDGJM_01955 0.0 oatA - - I - - - Acyltransferase family
IELDDGJM_01956 4.27e-59 yrhK - - S - - - YrhK-like protein
IELDDGJM_01957 8.55e-168 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IELDDGJM_01958 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IELDDGJM_01959 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
IELDDGJM_01960 6.1e-124 yrhH - - Q - - - methyltransferase
IELDDGJM_01961 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
IELDDGJM_01963 1.13e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
IELDDGJM_01964 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
IELDDGJM_01965 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
IELDDGJM_01966 2.46e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
IELDDGJM_01967 6.93e-49 yrhC - - S - - - YrhC-like protein
IELDDGJM_01968 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IELDDGJM_01969 7.04e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
IELDDGJM_01970 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IELDDGJM_01971 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
IELDDGJM_01972 8.52e-37 yrzA - - S - - - Protein of unknown function (DUF2536)
IELDDGJM_01973 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
IELDDGJM_01974 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
IELDDGJM_01975 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IELDDGJM_01976 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
IELDDGJM_01977 3.8e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
IELDDGJM_01978 6.57e-224 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
IELDDGJM_01979 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
IELDDGJM_01980 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IELDDGJM_01981 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
IELDDGJM_01982 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IELDDGJM_01983 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
IELDDGJM_01984 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IELDDGJM_01985 2.42e-239 yrrI - - S - - - AI-2E family transporter
IELDDGJM_01986 1.89e-169 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IELDDGJM_01987 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IELDDGJM_01988 1.32e-138 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IELDDGJM_01989 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IELDDGJM_01990 7.08e-85 hxlR - - K - - - transcriptional
IELDDGJM_01991 9.34e-136 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
IELDDGJM_01992 1.32e-125 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
IELDDGJM_01993 1.28e-261 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IELDDGJM_01994 1e-93 nucA - - M - - - Deoxyribonuclease NucA/NucB
IELDDGJM_01995 4.78e-91 nin - - S - - - Competence protein J (ComJ)
IELDDGJM_01996 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IELDDGJM_01997 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
IELDDGJM_01998 4.37e-56 yckC - - S - - - membrane
IELDDGJM_02000 6.23e-186 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IELDDGJM_02001 5.79e-147 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IELDDGJM_02002 1.53e-287 yciC - - S - - - GTPases (G3E family)
IELDDGJM_02003 1.47e-131 - - - M - - - ErfK YbiS YcfS YnhG
IELDDGJM_02004 2.11e-148 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
IELDDGJM_02005 1.18e-15 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
IELDDGJM_02006 1.11e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IELDDGJM_02007 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
IELDDGJM_02008 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IELDDGJM_02009 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IELDDGJM_02010 4.9e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
IELDDGJM_02011 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IELDDGJM_02012 1.93e-241 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
IELDDGJM_02013 2.95e-203 ycgS - - I - - - alpha/beta hydrolase fold
IELDDGJM_02014 2.41e-184 ycgR - - S ko:K07089 - ko00000 permeases
IELDDGJM_02015 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
IELDDGJM_02016 3.76e-286 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
IELDDGJM_02017 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IELDDGJM_02018 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IELDDGJM_02019 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IELDDGJM_02020 3.16e-186 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
IELDDGJM_02021 6.64e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
IELDDGJM_02022 1.11e-220 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
IELDDGJM_02023 1.45e-183 - - - Q - - - ubiE/COQ5 methyltransferase family
IELDDGJM_02024 4.28e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IELDDGJM_02025 3.46e-111 tmrB - - S - - - AAA domain
IELDDGJM_02026 3.03e-190 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IELDDGJM_02027 5.98e-120 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
IELDDGJM_02028 8.51e-193 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IELDDGJM_02029 3.44e-191 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
IELDDGJM_02030 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IELDDGJM_02031 2.93e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IELDDGJM_02032 3.73e-133 yhbD - - K - - - Protein of unknown function (DUF4004)
IELDDGJM_02033 5.32e-83 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IELDDGJM_02034 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
IELDDGJM_02035 2e-285 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
IELDDGJM_02036 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
IELDDGJM_02037 6.29e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
IELDDGJM_02038 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
IELDDGJM_02039 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
IELDDGJM_02040 3.95e-59 yhcC - - - - - - -
IELDDGJM_02041 2.48e-65 - - - - - - - -
IELDDGJM_02042 6.79e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_02043 1.32e-155 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_02044 5.09e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_02045 2.83e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IELDDGJM_02046 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
IELDDGJM_02047 6.12e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
IELDDGJM_02048 2.52e-107 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
IELDDGJM_02049 9.18e-106 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
IELDDGJM_02050 7.5e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IELDDGJM_02051 9.74e-72 yhcM - - - - - - -
IELDDGJM_02052 1.9e-95 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IELDDGJM_02053 5.01e-218 yhcP - - - - - - -
IELDDGJM_02054 9.06e-142 yhcQ - - M - - - Spore coat protein
IELDDGJM_02055 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IELDDGJM_02056 1.52e-135 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
IELDDGJM_02057 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IELDDGJM_02058 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
IELDDGJM_02059 7.16e-90 yhcV - - S - - - COG0517 FOG CBS domain
IELDDGJM_02060 1.24e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
IELDDGJM_02061 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IELDDGJM_02062 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IELDDGJM_02063 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IELDDGJM_02064 4.68e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IELDDGJM_02065 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IELDDGJM_02066 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IELDDGJM_02067 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
IELDDGJM_02068 1.54e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_02069 5.67e-146 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IELDDGJM_02070 1.34e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
IELDDGJM_02071 1.65e-51 yhdB - - S - - - YhdB-like protein
IELDDGJM_02072 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
IELDDGJM_02073 4.53e-270 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IELDDGJM_02074 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
IELDDGJM_02075 1.02e-304 ygxB - - M - - - Conserved TM helix
IELDDGJM_02076 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
IELDDGJM_02077 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
IELDDGJM_02078 1.05e-199 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IELDDGJM_02079 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_02080 1.3e-261 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IELDDGJM_02081 2.25e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IELDDGJM_02082 5.36e-316 yhdG - - E ko:K03294 - ko00000 amino acid
IELDDGJM_02083 4.29e-310 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IELDDGJM_02084 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IELDDGJM_02085 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IELDDGJM_02086 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
IELDDGJM_02087 5.03e-257 yhdL - - S - - - Sigma factor regulator N-terminal
IELDDGJM_02088 1.08e-111 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IELDDGJM_02089 9.18e-242 yhdN - - C - - - Aldo keto reductase
IELDDGJM_02090 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IELDDGJM_02091 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IELDDGJM_02092 4.07e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
IELDDGJM_02093 8.45e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IELDDGJM_02094 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
IELDDGJM_02095 6.84e-64 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IELDDGJM_02096 5.6e-85 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IELDDGJM_02097 5.23e-172 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IELDDGJM_02098 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
IELDDGJM_02099 3.04e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
IELDDGJM_02100 6.62e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IELDDGJM_02101 8.69e-195 nodB1 - - G - - - deacetylase
IELDDGJM_02102 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IELDDGJM_02103 4.9e-301 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IELDDGJM_02104 3.69e-107 nhaX - - T - - - Belongs to the universal stress protein A family
IELDDGJM_02105 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IELDDGJM_02106 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IELDDGJM_02107 4.25e-92 yheG - - GM - - - NAD(P)H-binding
IELDDGJM_02108 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
IELDDGJM_02109 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
IELDDGJM_02110 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
IELDDGJM_02111 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
IELDDGJM_02112 2.93e-259 yheB - - S - - - Belongs to the UPF0754 family
IELDDGJM_02113 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
IELDDGJM_02114 1.07e-146 yhaZ - - L - - - DNA alkylation repair enzyme
IELDDGJM_02115 5.95e-86 yhaZ - - L - - - DNA alkylation repair enzyme
IELDDGJM_02116 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
IELDDGJM_02117 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
IELDDGJM_02118 4.36e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
IELDDGJM_02119 9.24e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IELDDGJM_02121 1.54e-170 yhaR - - I - - - enoyl-CoA hydratase
IELDDGJM_02122 2.29e-36 - - - S - - - YhzD-like protein
IELDDGJM_02123 2.27e-214 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_02124 4.22e-271 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
IELDDGJM_02125 6.11e-297 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
IELDDGJM_02126 0.0 yhaN - - L - - - AAA domain
IELDDGJM_02127 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
IELDDGJM_02128 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
IELDDGJM_02129 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IELDDGJM_02130 1.4e-116 yhaK - - S - - - Putative zincin peptidase
IELDDGJM_02131 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
IELDDGJM_02132 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
IELDDGJM_02133 1.74e-54 yhaH - - S - - - YtxH-like protein
IELDDGJM_02134 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
IELDDGJM_02135 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IELDDGJM_02136 2.03e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IELDDGJM_02137 1.1e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
IELDDGJM_02138 5.15e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
IELDDGJM_02139 5.83e-161 ecsC - - S - - - EcsC protein family
IELDDGJM_02140 8.91e-291 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IELDDGJM_02141 2.31e-313 yhfA - - C - - - membrane
IELDDGJM_02142 8.58e-46 - - - C - - - Rubrerythrin
IELDDGJM_02143 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
IELDDGJM_02144 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IELDDGJM_02145 3.17e-260 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IELDDGJM_02146 3.41e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
IELDDGJM_02147 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IELDDGJM_02148 6.76e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_02149 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
IELDDGJM_02150 2.07e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IELDDGJM_02151 1.88e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
IELDDGJM_02152 1.55e-252 yhfE - - G - - - peptidase M42
IELDDGJM_02153 1.53e-93 - - - S - - - ASCH
IELDDGJM_02154 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IELDDGJM_02155 4.01e-181 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IELDDGJM_02156 8.2e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
IELDDGJM_02157 2.13e-143 yhfK - - GM - - - NmrA-like family
IELDDGJM_02158 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IELDDGJM_02159 7.65e-83 yhfM - - - - - - -
IELDDGJM_02160 6.5e-306 yhfN - - O - - - Peptidase M48
IELDDGJM_02161 1.7e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IELDDGJM_02162 3.46e-99 - - - K - - - acetyltransferase
IELDDGJM_02163 9.78e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
IELDDGJM_02164 5.35e-221 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IELDDGJM_02165 3.93e-140 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
IELDDGJM_02166 1.45e-244 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IELDDGJM_02167 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IELDDGJM_02168 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
IELDDGJM_02169 7.16e-258 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
IELDDGJM_02170 1.67e-120 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
IELDDGJM_02171 8.24e-238 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
IELDDGJM_02172 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IELDDGJM_02173 9.84e-45 yhzC - - S - - - IDEAL
IELDDGJM_02174 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
IELDDGJM_02175 1.16e-212 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IELDDGJM_02176 1.68e-55 yhjA - - S - - - Excalibur calcium-binding domain
IELDDGJM_02177 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IELDDGJM_02178 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
IELDDGJM_02179 4.13e-78 yhjD - - - - - - -
IELDDGJM_02180 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
IELDDGJM_02181 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IELDDGJM_02182 0.0 yhjG - - CH - - - FAD binding domain
IELDDGJM_02183 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
IELDDGJM_02184 1.04e-271 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
IELDDGJM_02185 1.89e-255 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IELDDGJM_02186 1.07e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
IELDDGJM_02187 6.26e-100 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
IELDDGJM_02188 3.75e-146 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
IELDDGJM_02189 1.77e-238 yhjM - - K - - - Transcriptional regulator
IELDDGJM_02190 2.5e-259 yhjN - - S ko:K07120 - ko00000 membrane
IELDDGJM_02191 6.73e-268 - - - EGP - - - Transmembrane secretion effector
IELDDGJM_02192 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
IELDDGJM_02193 9.3e-102 yhjR - - S - - - Rubrerythrin
IELDDGJM_02194 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
IELDDGJM_02195 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
IELDDGJM_02196 4.67e-279 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IELDDGJM_02197 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
IELDDGJM_02198 2.41e-62 yisB - - V - - - COG1403 Restriction endonuclease
IELDDGJM_02199 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
IELDDGJM_02200 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
IELDDGJM_02201 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
IELDDGJM_02202 1e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
IELDDGJM_02203 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
IELDDGJM_02204 7.41e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
IELDDGJM_02205 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
IELDDGJM_02206 1.04e-219 cotH - - M ko:K06330 - ko00000 Spore Coat
IELDDGJM_02207 2.19e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IELDDGJM_02208 2.4e-73 yisL - - S - - - UPF0344 protein
IELDDGJM_02209 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IELDDGJM_02210 4.29e-131 yisN - - S - - - Protein of unknown function (DUF2777)
IELDDGJM_02211 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IELDDGJM_02212 8.1e-151 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
IELDDGJM_02213 1.01e-310 yisQ - - V - - - Mate efflux family protein
IELDDGJM_02214 1.41e-207 yisR - - K - - - Transcriptional regulator
IELDDGJM_02215 4.83e-231 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IELDDGJM_02216 7.35e-249 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IELDDGJM_02217 1.41e-119 yisT - - S - - - DinB family
IELDDGJM_02218 1.28e-138 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
IELDDGJM_02219 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IELDDGJM_02220 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
IELDDGJM_02221 2.94e-195 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IELDDGJM_02222 2.26e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
IELDDGJM_02223 1.12e-207 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
IELDDGJM_02224 6.09e-65 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
IELDDGJM_02225 1.35e-74 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
IELDDGJM_02226 2.81e-82 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
IELDDGJM_02227 5.02e-158 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
IELDDGJM_02228 2.05e-178 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
IELDDGJM_02229 1.1e-138 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IELDDGJM_02230 1.49e-180 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IELDDGJM_02231 4.71e-122 rok - - K - - - Repressor of ComK
IELDDGJM_02232 1.47e-104 ykuV - - CO - - - thiol-disulfide
IELDDGJM_02233 2.31e-128 ykuU - - O - - - Alkyl hydroperoxide reductase
IELDDGJM_02234 2.37e-180 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
IELDDGJM_02235 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
IELDDGJM_02236 4.43e-273 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IELDDGJM_02237 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IELDDGJM_02238 6.96e-100 fld - - C ko:K03839 - ko00000 Flavodoxin
IELDDGJM_02239 2.12e-223 ykuO - - - - - - -
IELDDGJM_02240 5.02e-110 - - - C ko:K03839 - ko00000 Flavodoxin domain
IELDDGJM_02241 6.52e-216 ccpC - - K - - - Transcriptional regulator
IELDDGJM_02242 2.1e-99 ykuL - - S - - - CBS domain
IELDDGJM_02243 7.83e-38 ykzF - - S - - - Antirepressor AbbA
IELDDGJM_02244 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
IELDDGJM_02245 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
IELDDGJM_02247 2.91e-297 ykuI - - T - - - Diguanylate phosphodiesterase
IELDDGJM_02249 0.0 ybfG - - M - - - Putative peptidoglycan binding domain
IELDDGJM_02250 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IELDDGJM_02251 9.98e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
IELDDGJM_02252 4.8e-114 ykuD - - S - - - protein conserved in bacteria
IELDDGJM_02253 7.3e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IELDDGJM_02254 3.71e-110 ykyB - - S - - - YkyB-like protein
IELDDGJM_02255 2.86e-215 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
IELDDGJM_02256 1.05e-22 - - - - - - - -
IELDDGJM_02257 3.44e-282 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IELDDGJM_02258 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_02259 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IELDDGJM_02260 4.4e-171 ykwD - - J - - - protein with SCP PR1 domains
IELDDGJM_02261 1.64e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IELDDGJM_02262 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IELDDGJM_02263 1.86e-163 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IELDDGJM_02264 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
IELDDGJM_02265 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_02266 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IELDDGJM_02267 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
IELDDGJM_02268 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IELDDGJM_02269 1.39e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
IELDDGJM_02271 2.69e-229 ykvZ - - K - - - Transcriptional regulator
IELDDGJM_02272 9.15e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IELDDGJM_02273 3.99e-09 - - - - - - - -
IELDDGJM_02274 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IELDDGJM_02275 1.66e-116 stoA - - CO - - - thiol-disulfide
IELDDGJM_02276 2.26e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IELDDGJM_02277 1.24e-139 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
IELDDGJM_02278 7.48e-39 - - - - - - - -
IELDDGJM_02279 5.43e-35 ykvS - - S - - - protein conserved in bacteria
IELDDGJM_02280 4.43e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
IELDDGJM_02281 5.49e-47 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IELDDGJM_02282 4.48e-115 - - - L - - - Belongs to the 'phage' integrase family
IELDDGJM_02283 4.47e-56 - - - - - - - -
IELDDGJM_02284 8.29e-312 - - - I - - - Pfam Lipase (class 3)
IELDDGJM_02285 5.57e-48 - - - S - - - Protein of unknown function (DUF1433)
IELDDGJM_02286 7.57e-60 - - - S - - - Protein of unknown function (DUF1433)
IELDDGJM_02287 1.18e-126 yoeB - - S - - - IseA DL-endopeptidase inhibitor
IELDDGJM_02288 9.8e-313 yoeA - - V - - - MATE efflux family protein
IELDDGJM_02289 4.05e-242 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
IELDDGJM_02290 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IELDDGJM_02291 1.5e-47 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IELDDGJM_02292 9e-203 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IELDDGJM_02293 1.36e-47 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IELDDGJM_02294 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IELDDGJM_02295 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IELDDGJM_02296 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
IELDDGJM_02297 3.06e-185 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
IELDDGJM_02298 2e-182 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
IELDDGJM_02299 4.39e-44 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
IELDDGJM_02300 4.81e-81 yngL - - S - - - Protein of unknown function (DUF1360)
IELDDGJM_02301 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
IELDDGJM_02302 5.98e-265 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IELDDGJM_02303 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IELDDGJM_02304 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
IELDDGJM_02305 1.98e-40 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
IELDDGJM_02306 1.36e-211 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
IELDDGJM_02307 8.22e-173 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
IELDDGJM_02308 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IELDDGJM_02309 8.35e-212 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
IELDDGJM_02310 2.01e-134 yngC - - S - - - membrane-associated protein
IELDDGJM_02311 2.63e-208 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IELDDGJM_02312 1.28e-102 yngA - - S - - - membrane
IELDDGJM_02313 1.5e-33 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IELDDGJM_02314 3.59e-124 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IELDDGJM_02315 2.08e-171 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
IELDDGJM_02316 2.12e-114 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
IELDDGJM_02318 2.22e-53 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
IELDDGJM_02319 2.07e-276 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
IELDDGJM_02320 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IELDDGJM_02321 6.15e-75 ynfC - - - - - - -
IELDDGJM_02322 1.82e-18 - - - - - - - -
IELDDGJM_02323 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IELDDGJM_02324 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IELDDGJM_02325 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
IELDDGJM_02326 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IELDDGJM_02327 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
IELDDGJM_02328 4.68e-71 yneQ - - - - - - -
IELDDGJM_02329 4.02e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
IELDDGJM_02330 2.7e-47 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
IELDDGJM_02332 9.26e-10 - - - S - - - Fur-regulated basic protein B
IELDDGJM_02333 5.96e-117 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IELDDGJM_02334 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IELDDGJM_02335 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
IELDDGJM_02336 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
IELDDGJM_02337 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
IELDDGJM_02338 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
IELDDGJM_02339 0.0 yddG - - S - - - maturation of SSU-rRNA
IELDDGJM_02340 1.35e-55 - - - S - - - Domain of unknown function (DUF1874)
IELDDGJM_02341 0.0 yddE - - S - - - AAA-like domain
IELDDGJM_02342 2.15e-121 yddD - - S - - - TcpE family
IELDDGJM_02343 3.41e-54 yddC - - - - - - -
IELDDGJM_02344 5.35e-216 yddB - - S - - - Conjugative transposon protein TcpC
IELDDGJM_02346 1.47e-55 yddA - - - - - - -
IELDDGJM_02349 1.02e-260 nicK - - L ko:K07467 - ko00000 Replication initiation factor
IELDDGJM_02350 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
IELDDGJM_02351 1.22e-49 - - - S - - - Bacterial protein of unknown function (DUF961)
IELDDGJM_02353 9.23e-45 - - - - - - - -
IELDDGJM_02354 3.32e-20 - - - - - - - -
IELDDGJM_02355 3.16e-55 - - - K - - - Transcriptional
IELDDGJM_02356 1.79e-57 - - - E - - - IrrE N-terminal-like domain
IELDDGJM_02357 7.38e-93 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IELDDGJM_02359 1.26e-29 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
IELDDGJM_02360 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
IELDDGJM_02361 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
IELDDGJM_02362 4.39e-112 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
IELDDGJM_02363 1.37e-191 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
IELDDGJM_02364 6.07e-126 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
IELDDGJM_02365 3.3e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IELDDGJM_02366 4.83e-227 ccpB - - K - - - Transcriptional regulator
IELDDGJM_02367 1.24e-181 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
IELDDGJM_02368 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IELDDGJM_02369 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IELDDGJM_02370 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
IELDDGJM_02371 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IELDDGJM_02372 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IELDDGJM_02373 7.41e-45 yyzM - - S - - - protein conserved in bacteria
IELDDGJM_02374 5.34e-227 yyaD - - S - - - Membrane
IELDDGJM_02375 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
IELDDGJM_02376 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IELDDGJM_02377 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
IELDDGJM_02378 8.9e-96 - - - S - - - Bacterial PH domain
IELDDGJM_02379 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IELDDGJM_02380 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IELDDGJM_02381 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IELDDGJM_02382 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IELDDGJM_02383 3.04e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
IELDDGJM_02384 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IELDDGJM_02385 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IELDDGJM_02386 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IELDDGJM_02387 2.83e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IELDDGJM_02388 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
IELDDGJM_02389 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IELDDGJM_02390 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
IELDDGJM_02391 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IELDDGJM_02392 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IELDDGJM_02393 4.84e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
IELDDGJM_02394 4.58e-85 ywnA - - K - - - Transcriptional regulator
IELDDGJM_02395 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IELDDGJM_02396 6.46e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
IELDDGJM_02397 6.75e-67 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
IELDDGJM_02398 1.57e-143 - - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
IELDDGJM_02399 9.77e-155 - - - S ko:K11962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
IELDDGJM_02400 1.88e-233 - - - E ko:K01998,ko:K11961 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IELDDGJM_02401 1.3e-189 - - - E ko:K11960 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IELDDGJM_02402 1.93e-277 - - - E ko:K11959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
IELDDGJM_02403 2.15e-19 csbD - - K - - - CsbD-like
IELDDGJM_02404 3.22e-109 ywmF - - S - - - Peptidase M50
IELDDGJM_02405 4.39e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IELDDGJM_02406 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IELDDGJM_02407 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IELDDGJM_02409 5.64e-153 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IELDDGJM_02410 4.28e-154 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IELDDGJM_02411 3.05e-237 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
IELDDGJM_02412 2.02e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IELDDGJM_02413 3.81e-171 ywmB - - S - - - TATA-box binding
IELDDGJM_02414 4.54e-45 ywzB - - S - - - membrane
IELDDGJM_02415 7.16e-114 ywmA - - - - - - -
IELDDGJM_02416 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
IELDDGJM_02417 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IELDDGJM_02418 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IELDDGJM_02419 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IELDDGJM_02420 3.93e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IELDDGJM_02421 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IELDDGJM_02422 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IELDDGJM_02423 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
IELDDGJM_02424 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
IELDDGJM_02425 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IELDDGJM_02426 1.78e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IELDDGJM_02427 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
IELDDGJM_02428 9.57e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
IELDDGJM_02429 9.54e-102 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IELDDGJM_02430 6.48e-117 mntP - - P - - - Probably functions as a manganese efflux pump
IELDDGJM_02431 1.43e-248 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IELDDGJM_02432 2.55e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
IELDDGJM_02433 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
IELDDGJM_02434 3.95e-73 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IELDDGJM_02436 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IELDDGJM_02437 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IELDDGJM_02438 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IELDDGJM_02439 2.45e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IELDDGJM_02440 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
IELDDGJM_02441 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IELDDGJM_02442 4.06e-134 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
IELDDGJM_02443 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
IELDDGJM_02444 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IELDDGJM_02445 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
IELDDGJM_02446 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IELDDGJM_02447 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IELDDGJM_02448 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
IELDDGJM_02449 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
IELDDGJM_02450 9.11e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
IELDDGJM_02451 2.74e-16 orfX1 - - L - - - Transposase
IELDDGJM_02452 6.87e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IELDDGJM_02453 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
IELDDGJM_02454 8.97e-253 yutH - - S - - - Spore coat protein
IELDDGJM_02455 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
IELDDGJM_02456 3.03e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IELDDGJM_02457 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
IELDDGJM_02458 2.17e-61 yutD - - S - - - protein conserved in bacteria
IELDDGJM_02459 2.71e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IELDDGJM_02460 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IELDDGJM_02461 7.63e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
IELDDGJM_02462 2.54e-168 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
IELDDGJM_02463 1.33e-59 yunC - - S - - - Domain of unknown function (DUF1805)
IELDDGJM_02464 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IELDDGJM_02465 2.65e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
IELDDGJM_02466 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
IELDDGJM_02467 2.72e-82 yunG - - - - - - -
IELDDGJM_02468 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IELDDGJM_02469 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
IELDDGJM_02470 3.14e-295 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
IELDDGJM_02471 1.58e-283 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
IELDDGJM_02472 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
IELDDGJM_02473 1.21e-71 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
IELDDGJM_02474 1.4e-121 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IELDDGJM_02475 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IELDDGJM_02476 4.27e-188 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IELDDGJM_02477 3.58e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
IELDDGJM_02478 2.15e-235 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IELDDGJM_02479 1.65e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IELDDGJM_02480 2.05e-295 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IELDDGJM_02481 2.1e-214 bsn - - L - - - Ribonuclease
IELDDGJM_02482 1.09e-30 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
IELDDGJM_02483 1.3e-93 - - - E - - - AzlC protein
IELDDGJM_02484 8.01e-198 gntR9 - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IELDDGJM_02485 4.05e-46 - - - L - - - COG3666 Transposase and inactivated derivatives
IELDDGJM_02486 1.46e-82 - - - L - - - COG3666 Transposase and inactivated derivatives
IELDDGJM_02488 2.04e-14 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 methionine gamma-lyase
IELDDGJM_02489 1.01e-161 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 methionine gamma-lyase
IELDDGJM_02490 1.3e-27 - - - I - - - Fatty acid desaturase
IELDDGJM_02491 4.23e-100 - - - I - - - Fatty acid desaturase
IELDDGJM_02492 0.000162 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IELDDGJM_02493 3.78e-250 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IELDDGJM_02494 2.5e-174 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
IELDDGJM_02495 1.64e-187 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
IELDDGJM_02496 1.17e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
IELDDGJM_02497 1.51e-234 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IELDDGJM_02498 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
IELDDGJM_02499 8.79e-263 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
IELDDGJM_02501 3.35e-56 - - - - - - - -
IELDDGJM_02502 1.11e-139 yodC - - C - - - nitroreductase
IELDDGJM_02503 2.63e-73 yodB - - K - - - transcriptional
IELDDGJM_02504 1.33e-82 iolK - - S - - - tautomerase
IELDDGJM_02505 3.09e-288 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
IELDDGJM_02506 3.94e-14 - - - - - - - -
IELDDGJM_02507 8.27e-103 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
IELDDGJM_02508 8.13e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
IELDDGJM_02509 1.85e-58 - - - - - - - -
IELDDGJM_02510 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
IELDDGJM_02511 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
IELDDGJM_02512 8.33e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IELDDGJM_02513 1.89e-309 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
IELDDGJM_02515 6.12e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IELDDGJM_02516 9.32e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
IELDDGJM_02517 8.64e-263 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IELDDGJM_02518 4.94e-140 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IELDDGJM_02519 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
IELDDGJM_02520 0.0 yojO - - P - - - Von Willebrand factor
IELDDGJM_02521 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IELDDGJM_02522 2.59e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IELDDGJM_02523 4.7e-214 yocS - - S ko:K03453 - ko00000 -transporter
IELDDGJM_02524 1.45e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IELDDGJM_02525 1.86e-209 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
IELDDGJM_02526 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
IELDDGJM_02527 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IELDDGJM_02528 3.19e-41 yozC - - - - - - -
IELDDGJM_02529 2.17e-74 yozO - - S - - - Bacterial PH domain
IELDDGJM_02530 1.83e-49 yocN - - - - - - -
IELDDGJM_02531 2.94e-55 yozN - - - - - - -
IELDDGJM_02532 3.82e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IELDDGJM_02533 4.77e-42 - - - - - - - -
IELDDGJM_02534 4.29e-70 yocL - - - - - - -
IELDDGJM_02535 1.42e-107 yocK - - T - - - general stress protein
IELDDGJM_02536 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IELDDGJM_02537 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IELDDGJM_02538 4.36e-170 yocH - - M - - - COG1388 FOG LysM repeat
IELDDGJM_02539 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IELDDGJM_02540 3.51e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_02541 7.72e-256 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
IELDDGJM_02542 9.94e-243 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
IELDDGJM_02543 3.49e-118 yocC - - - - - - -
IELDDGJM_02544 6.12e-184 - - - - - - - -
IELDDGJM_02545 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
IELDDGJM_02546 1.06e-188 yfkD - - S - - - YfkD-like protein
IELDDGJM_02547 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
IELDDGJM_02548 2.22e-277 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IELDDGJM_02549 1.64e-12 - - - - - - - -
IELDDGJM_02550 1.13e-182 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
IELDDGJM_02551 1.03e-66 yfkI - - S - - - gas vesicle protein
IELDDGJM_02552 1.98e-102 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IELDDGJM_02553 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
IELDDGJM_02554 1.03e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IELDDGJM_02555 1.83e-112 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IELDDGJM_02556 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IELDDGJM_02557 6.16e-160 frp - - C - - - nitroreductase
IELDDGJM_02558 1.45e-171 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
IELDDGJM_02559 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
IELDDGJM_02560 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IELDDGJM_02561 3.92e-142 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
IELDDGJM_02562 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
IELDDGJM_02563 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IELDDGJM_02564 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IELDDGJM_02565 3.83e-177 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IELDDGJM_02566 3.5e-64 yflH - - S - - - Protein of unknown function (DUF3243)
IELDDGJM_02567 6.9e-27 yflI - - - - - - -
IELDDGJM_02568 5.7e-150 yflK - - S - - - protein conserved in bacteria
IELDDGJM_02569 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
IELDDGJM_02570 9.67e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IELDDGJM_02571 2.82e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IELDDGJM_02572 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IELDDGJM_02573 6.6e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
IELDDGJM_02574 1.33e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
IELDDGJM_02575 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IELDDGJM_02576 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
IELDDGJM_02577 7.03e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
IELDDGJM_02578 8.1e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
IELDDGJM_02579 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IELDDGJM_02580 7.09e-229 - - - L - - - ISXO2-like transposase domain
IELDDGJM_02581 1e-96 yycN - - K - - - FR47-like protein
IELDDGJM_02582 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
IELDDGJM_02583 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
IELDDGJM_02584 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IELDDGJM_02585 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IELDDGJM_02586 4.18e-256 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
IELDDGJM_02587 4.19e-75 ydbP - - CO - - - Thioredoxin
IELDDGJM_02588 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IELDDGJM_02590 1.49e-26 - - - S - - - Fur-regulated basic protein B
IELDDGJM_02591 5.03e-278 ydbM - - I - - - acyl-CoA dehydrogenase
IELDDGJM_02592 9.32e-70 ydbL - - - - - - -
IELDDGJM_02593 8.57e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IELDDGJM_02594 5.36e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_02596 1.32e-230 ydbI - - S - - - AI-2E family transporter
IELDDGJM_02597 5.16e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IELDDGJM_02598 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IELDDGJM_02599 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IELDDGJM_02600 1.23e-251 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IELDDGJM_02601 2.74e-176 ydbD - - P ko:K07217 - ko00000 Catalase
IELDDGJM_02602 1.49e-81 ydbC - - S - - - Domain of unknown function (DUF4937
IELDDGJM_02603 3.09e-78 ydbB - - G - - - Cupin domain
IELDDGJM_02604 1.83e-09 gsiB - - S ko:K06884 - ko00000 general stress protein
IELDDGJM_02605 1.4e-113 ydbA - - P - - - EcsC protein family
IELDDGJM_02606 3.92e-44 ydbA - - P - - - EcsC protein family
IELDDGJM_02607 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
IELDDGJM_02608 1.67e-42 ydaS - - S - - - membrane
IELDDGJM_02609 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IELDDGJM_02610 2.5e-52 - - - - - - - -
IELDDGJM_02611 3.27e-24 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IELDDGJM_02612 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IELDDGJM_02613 4.05e-98 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IELDDGJM_02614 0.0 ydaO - - E - - - amino acid
IELDDGJM_02615 7.26e-237 ydaN - - S - - - Bacterial cellulose synthase subunit
IELDDGJM_02616 7.66e-234 ydaN - - S - - - Bacterial cellulose synthase subunit
IELDDGJM_02617 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
IELDDGJM_02618 4.3e-221 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
IELDDGJM_02619 2.78e-164 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
IELDDGJM_02620 9.49e-39 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
IELDDGJM_02621 7.07e-115 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
IELDDGJM_02622 2.33e-262 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
IELDDGJM_02623 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IELDDGJM_02624 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IELDDGJM_02625 5.44e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
IELDDGJM_02626 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
IELDDGJM_02627 9.4e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
IELDDGJM_02628 1.4e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IELDDGJM_02629 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IELDDGJM_02631 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IELDDGJM_02632 4.63e-177 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
IELDDGJM_02633 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IELDDGJM_02634 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IELDDGJM_02635 6.19e-39 ywdA - - - - - - -
IELDDGJM_02636 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IELDDGJM_02637 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
IELDDGJM_02638 1.69e-143 ywdD - - - - - - -
IELDDGJM_02640 1.34e-191 ywdF - - S - - - Glycosyltransferase like family 2
IELDDGJM_02641 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IELDDGJM_02642 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IELDDGJM_02643 1.08e-63 ywdI - - S - - - Family of unknown function (DUF5327)
IELDDGJM_02644 3.59e-301 ywdJ - - F - - - Xanthine uracil
IELDDGJM_02645 2.26e-78 ywdK - - S - - - small membrane protein
IELDDGJM_02646 1.21e-110 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IELDDGJM_02647 8.08e-187 spsA - - M - - - Spore Coat
IELDDGJM_02648 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
IELDDGJM_02649 6.18e-283 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
IELDDGJM_02650 8.17e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
IELDDGJM_02651 7.93e-271 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
IELDDGJM_02652 2.47e-164 spsF - - M ko:K07257 - ko00000 Spore Coat
IELDDGJM_02653 4.71e-239 spsG - - M - - - Spore Coat
IELDDGJM_02654 7.45e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IELDDGJM_02655 6.14e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IELDDGJM_02656 4.72e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IELDDGJM_02657 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
IELDDGJM_02658 3.7e-101 - - - - - - - -
IELDDGJM_02659 5.38e-260 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IELDDGJM_02660 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IELDDGJM_02661 0.0 rocB - - E - - - arginine degradation protein
IELDDGJM_02662 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IELDDGJM_02663 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IELDDGJM_02664 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IELDDGJM_02665 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IELDDGJM_02666 1.77e-151 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
IELDDGJM_02667 3.09e-291 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
IELDDGJM_02668 1.31e-160 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IELDDGJM_02669 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IELDDGJM_02670 1.7e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
IELDDGJM_02671 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IELDDGJM_02672 2.23e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
IELDDGJM_02673 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
IELDDGJM_02674 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IELDDGJM_02675 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
IELDDGJM_02676 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IELDDGJM_02677 7.25e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IELDDGJM_02678 6.35e-190 ytpQ - - S - - - Belongs to the UPF0354 family
IELDDGJM_02679 3.17e-75 ytpP - - CO - - - Thioredoxin
IELDDGJM_02680 4.89e-63 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
IELDDGJM_02681 4.88e-29 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
IELDDGJM_02682 3.56e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
IELDDGJM_02683 1.17e-67 ytzB - - S - - - small secreted protein
IELDDGJM_02684 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IELDDGJM_02685 1.06e-190 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IELDDGJM_02686 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IELDDGJM_02687 9.51e-61 ytzH - - S - - - YtzH-like protein
IELDDGJM_02688 3.02e-192 ytmP - - M - - - Phosphotransferase
IELDDGJM_02689 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
IELDDGJM_02690 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
IELDDGJM_02691 1.58e-208 ytlQ - - - - - - -
IELDDGJM_02692 7.41e-131 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IELDDGJM_02693 8.59e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IELDDGJM_02694 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
IELDDGJM_02695 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
IELDDGJM_02696 4.28e-256 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
IELDDGJM_02697 5.66e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IELDDGJM_02698 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
IELDDGJM_02699 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
IELDDGJM_02700 1.04e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IELDDGJM_02701 3.51e-190 ybbH - - K - - - transcriptional
IELDDGJM_02702 1.64e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IELDDGJM_02703 3.86e-38 ybbJ - - J - - - acetyltransferase
IELDDGJM_02704 4.03e-99 ybbK - - S - - - Protein of unknown function (DUF523)
IELDDGJM_02710 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IELDDGJM_02711 4.54e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IELDDGJM_02712 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IELDDGJM_02713 4.13e-290 ybbR - - S - - - protein conserved in bacteria
IELDDGJM_02714 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IELDDGJM_02715 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IELDDGJM_02716 1.16e-147 - - - L - - - Bacterial dnaA protein
IELDDGJM_02717 1.17e-73 - - - L - - - Integrase core domain
IELDDGJM_02718 9.25e-89 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Metallo-beta-lactamase superfamily
IELDDGJM_02719 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
IELDDGJM_02720 0.0 - - - Q - - - Non-ribosomal peptide synthetase modules and related
IELDDGJM_02721 0.0 - - - Q - - - Acyl transferase domain in polyketide synthase (PKS) enzymes.
IELDDGJM_02722 1.73e-63 ttr - - K - - - GCN5 family acetyltransferase
IELDDGJM_02723 0.0 - - - Q - - - PFAM AMP-dependent synthetase and ligase
IELDDGJM_02724 6.61e-67 - - - I - - - Fatty acid hydroxylase superfamily
IELDDGJM_02725 8.87e-160 - - - C - - - Luciferase-like monooxygenase
IELDDGJM_02726 9.4e-96 - - - G - - - Major facilitator Superfamily
IELDDGJM_02727 6.26e-42 - - - S - - - SIR2-like domain
IELDDGJM_02728 3.09e-267 - - - L ko:K07495 - ko00000 COG3385 FOG Transposase and inactivated derivatives
IELDDGJM_02729 1.64e-70 - - - S - - - SIR2-like domain
IELDDGJM_02730 3.82e-77 - - - S - - - SIR2-like domain
IELDDGJM_02732 8.69e-74 - - - S - - - PFAM ThiJ PfpI domain protein
IELDDGJM_02733 1.5e-226 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IELDDGJM_02734 3.59e-152 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
IELDDGJM_02735 5.25e-127 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IELDDGJM_02736 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IELDDGJM_02737 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
IELDDGJM_02738 1.63e-121 ybcF - - P - - - carbonic anhydrase
IELDDGJM_02740 4.6e-63 - - - - - - - -
IELDDGJM_02741 2.96e-79 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
IELDDGJM_02742 9.45e-67 - - - K - - - Helix-turn-helix domain
IELDDGJM_02743 9.37e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
IELDDGJM_02745 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
IELDDGJM_02746 0.0 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
IELDDGJM_02747 1.9e-170 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IELDDGJM_02748 1e-310 skfF - - S - - - ABC transporter
IELDDGJM_02749 3.88e-118 - - - C - - - HEAT repeats
IELDDGJM_02750 5.88e-103 - - - CO - - - Thioredoxin-like domain
IELDDGJM_02751 1.82e-229 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IELDDGJM_02752 6.9e-158 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
IELDDGJM_02753 4.22e-214 - - - T - - - His Kinase A (phospho-acceptor) domain
IELDDGJM_02755 1.68e-179 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
IELDDGJM_02756 3.67e-193 ybdN - - - - - - -
IELDDGJM_02757 1e-270 ybdO - - S - - - Domain of unknown function (DUF4885)
IELDDGJM_02758 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IELDDGJM_02759 2.23e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
IELDDGJM_02760 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
IELDDGJM_02761 5.05e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
IELDDGJM_02762 4.25e-311 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
IELDDGJM_02763 1.3e-53 ybyB - - - - - - -
IELDDGJM_02764 0.0 ybeC - - E - - - amino acid
IELDDGJM_02765 1.65e-209 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
IELDDGJM_02766 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
IELDDGJM_02767 1.92e-42 - - - S - - - Protein of unknown function (DUF2651)
IELDDGJM_02768 3.74e-212 ybfA - - K - - - FR47-like protein
IELDDGJM_02769 3.21e-285 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
IELDDGJM_02771 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
IELDDGJM_02772 4.15e-205 ybfH - - EG - - - EamA-like transporter family
IELDDGJM_02773 2.88e-185 ybfI - - K - - - AraC-like ligand binding domain
IELDDGJM_02774 6.26e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IELDDGJM_02775 1.69e-228 mpr - - M - - - Belongs to the peptidase S1B family
IELDDGJM_02777 1.71e-208 - - - S - - - Alpha/beta hydrolase family
IELDDGJM_02778 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IELDDGJM_02779 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
IELDDGJM_02780 2.5e-189 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IELDDGJM_02781 3.88e-60 ybfN - - - - - - -
IELDDGJM_02782 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
IELDDGJM_02783 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
IELDDGJM_02784 2.46e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IELDDGJM_02785 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IELDDGJM_02786 1.5e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IELDDGJM_02787 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
IELDDGJM_02789 6.64e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IELDDGJM_02790 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IELDDGJM_02791 6.14e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
IELDDGJM_02793 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IELDDGJM_02794 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IELDDGJM_02795 5.88e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_02796 5.76e-216 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
IELDDGJM_02797 3.37e-221 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
IELDDGJM_02798 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IELDDGJM_02799 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IELDDGJM_02800 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IELDDGJM_02801 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
IELDDGJM_02802 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
IELDDGJM_02803 4.69e-122 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
IELDDGJM_02804 1.92e-67 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
IELDDGJM_02805 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
IELDDGJM_02806 2.44e-216 eamA1 - - EG - - - spore germination
IELDDGJM_02807 9.12e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IELDDGJM_02808 1.84e-212 ycbM - - T - - - Histidine kinase
IELDDGJM_02809 9.59e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_02810 4.75e-147 - - - S - - - ABC-2 family transporter protein
IELDDGJM_02811 2.48e-73 ycbP - - S - - - Protein of unknown function (DUF2512)
IELDDGJM_02812 2.05e-99 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
IELDDGJM_02813 3.38e-06 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma factor
IELDDGJM_02814 6.43e-65 XK27_07210 - - S - - - B3/4 domain
IELDDGJM_02816 5.42e-11 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IELDDGJM_02817 6.95e-51 - - - S ko:K07006 - ko00000 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase
IELDDGJM_02818 1.56e-42 - - - S - - - CGNR zinc finger
IELDDGJM_02819 1.07e-123 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartate-semialdehyde dehydrogenase family
IELDDGJM_02820 1.78e-152 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
IELDDGJM_02821 3.41e-102 - - - I - - - Fatty acid desaturase
IELDDGJM_02822 6.05e-103 - - - S - - - Protein of unknown function (DUF444)
IELDDGJM_02823 1.64e-56 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate synthase activity
IELDDGJM_02824 8.48e-153 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
IELDDGJM_02825 2.93e-91 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
IELDDGJM_02826 9.39e-246 - - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IELDDGJM_02827 1.75e-83 ycbR - - T - - - vWA found in TerF C terminus
IELDDGJM_02828 1.5e-55 ycbR - - T - - - vWA found in TerF C terminus
IELDDGJM_02829 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
IELDDGJM_02830 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IELDDGJM_02831 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IELDDGJM_02832 2.32e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IELDDGJM_02833 1.9e-256 ycbU - - E - - - Selenocysteine lyase
IELDDGJM_02834 2.39e-300 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
IELDDGJM_02835 7.64e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IELDDGJM_02836 2.3e-255 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IELDDGJM_02837 4.67e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
IELDDGJM_02838 6.61e-73 - - - S - - - RDD family
IELDDGJM_02839 5.86e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
IELDDGJM_02840 3.13e-171 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IELDDGJM_02841 3.81e-160 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
IELDDGJM_02842 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
IELDDGJM_02843 1.09e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IELDDGJM_02844 2.77e-221 yccK - - C - - - Aldo keto reductase
IELDDGJM_02845 5.5e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
IELDDGJM_02846 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IELDDGJM_02847 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IELDDGJM_02848 2.65e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IELDDGJM_02849 6.95e-159 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
IELDDGJM_02850 1.62e-44 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
IELDDGJM_02851 1.14e-178 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
IELDDGJM_02852 2.34e-223 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IELDDGJM_02853 2.22e-191 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IELDDGJM_02854 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IELDDGJM_02855 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IELDDGJM_02856 1.88e-172 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IELDDGJM_02857 1.1e-233 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IELDDGJM_02858 1.78e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
IELDDGJM_02859 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IELDDGJM_02860 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IELDDGJM_02861 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
IELDDGJM_02862 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
IELDDGJM_02863 2.96e-245 yceH - - P - - - Belongs to the TelA family
IELDDGJM_02864 5.45e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
IELDDGJM_02865 6.11e-260 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
IELDDGJM_02866 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IELDDGJM_02867 5.2e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
IELDDGJM_02868 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IELDDGJM_02869 4.73e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IELDDGJM_02870 7.07e-272 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
IELDDGJM_02871 2.36e-50 ycgA - - S - - - Membrane
IELDDGJM_02872 1.55e-141 ycgA - - S - - - Membrane
IELDDGJM_02873 3.04e-39 ycgA - - S - - - Membrane
IELDDGJM_02874 1.83e-103 ycgB - - - - - - -
IELDDGJM_02875 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
IELDDGJM_02876 1.31e-121 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
IELDDGJM_02877 4.73e-306 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IELDDGJM_02878 2.29e-29 ywtC - - - - - - -
IELDDGJM_02879 4.46e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IELDDGJM_02880 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
IELDDGJM_02881 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
IELDDGJM_02882 1.55e-226 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
IELDDGJM_02883 5.68e-201 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IELDDGJM_02884 3.79e-83 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IELDDGJM_02885 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IELDDGJM_02886 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IELDDGJM_02887 9.04e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
IELDDGJM_02888 1.14e-118 batE - - T - - - Sh3 type 3 domain protein
IELDDGJM_02889 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
IELDDGJM_02890 1.45e-124 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
IELDDGJM_02891 6.15e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
IELDDGJM_02892 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
IELDDGJM_02893 3.36e-218 alsR - - K - - - LysR substrate binding domain
IELDDGJM_02894 1.79e-227 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IELDDGJM_02895 1.06e-162 ywrJ - - - - - - -
IELDDGJM_02896 4.21e-112 cotB - - - ko:K06325 - ko00000 -
IELDDGJM_02897 3.12e-29 cotB - - - ko:K06325 - ko00000 -
IELDDGJM_02898 1.2e-264 cotH - - M ko:K06330 - ko00000 Spore Coat
IELDDGJM_02899 5.01e-18 - - - - - - - -
IELDDGJM_02900 3.43e-140 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IELDDGJM_02901 3.8e-69 - - - S - - - Domain of unknown function (DUF4181)
IELDDGJM_02902 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IELDDGJM_02903 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IELDDGJM_02904 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
IELDDGJM_02905 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
IELDDGJM_02907 7.23e-65 ywqN - - S - - - NAD(P)H-dependent
IELDDGJM_02908 6.13e-30 ywqN - - S - - - NAD(P)H-dependent
IELDDGJM_02909 1.36e-208 - - - K - - - Transcriptional regulator
IELDDGJM_02910 1.77e-149 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IELDDGJM_02912 7.62e-296 ywqJ - - S - - - Pre-toxin TG
IELDDGJM_02913 2.47e-50 ywqI - - S - - - Family of unknown function (DUF5344)
IELDDGJM_02915 1.45e-108 ywqG - - S - - - Domain of unknown function (DUF1963)
IELDDGJM_02916 1.3e-38 ywqG - - S - - - Domain of unknown function (DUF1963)
IELDDGJM_02917 5.33e-111 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IELDDGJM_02918 0.0 yddG - - S - - - maturation of SSU-rRNA
IELDDGJM_02919 3.85e-72 - - - S - - - Domain of unknown function (DUF1874)
IELDDGJM_02920 0.0 yddE - - S - - - AAA-like domain
IELDDGJM_02921 9.11e-123 yddD - - S - - - TcpE family
IELDDGJM_02922 3.41e-54 yddC - - - - - - -
IELDDGJM_02923 1.13e-217 yddB - - S - - - Conjugative transposon protein TcpC
IELDDGJM_02924 2.05e-62 yddA - - - - - - -
IELDDGJM_02927 1.31e-12 - - - S - - - Domain of Unknown Function with PDB structure (DUF3850)
IELDDGJM_02928 6.62e-257 nicK - - L ko:K07467 - ko00000 Replication initiation factor
IELDDGJM_02929 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
IELDDGJM_02931 5.01e-44 - - - S - - - Bacterial protein of unknown function (DUF961)
IELDDGJM_02933 9.17e-54 - - - - - - - -
IELDDGJM_02934 3.65e-23 - - - - - - - -
IELDDGJM_02935 1.83e-79 - - - K - - - Transcriptional
IELDDGJM_02936 1.78e-111 - - - E - - - IrrE N-terminal-like domain
IELDDGJM_02937 2.06e-259 ydcL - - L - - - Belongs to the 'phage' integrase family
IELDDGJM_02938 1.57e-97 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
IELDDGJM_02939 6.26e-275 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IELDDGJM_02940 2.52e-69 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
IELDDGJM_02941 7.79e-60 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
IELDDGJM_02942 7.29e-253 - - - O - - - Pyridine nucleotide-disulphide oxidoreductase
IELDDGJM_02943 2.08e-73 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
IELDDGJM_02951 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
IELDDGJM_02952 1.08e-140 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
IELDDGJM_02953 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IELDDGJM_02954 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IELDDGJM_02955 1.9e-68 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
IELDDGJM_02956 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
IELDDGJM_02957 2.45e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IELDDGJM_02958 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
IELDDGJM_02959 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
IELDDGJM_02960 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
IELDDGJM_02961 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IELDDGJM_02962 7.21e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IELDDGJM_02963 1.9e-233 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
IELDDGJM_02964 1.32e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IELDDGJM_02965 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
IELDDGJM_02966 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
IELDDGJM_02967 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
IELDDGJM_02968 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IELDDGJM_02969 3.53e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
IELDDGJM_02970 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IELDDGJM_02971 6.44e-62 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IELDDGJM_02972 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
IELDDGJM_02973 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
IELDDGJM_02974 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IELDDGJM_02975 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
IELDDGJM_02976 6.7e-72 yusE - - CO - - - Thioredoxin
IELDDGJM_02977 2.55e-95 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
IELDDGJM_02978 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
IELDDGJM_02979 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IELDDGJM_02980 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
IELDDGJM_02981 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IELDDGJM_02982 7.42e-276 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
IELDDGJM_02983 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
IELDDGJM_02984 1.11e-13 - - - S - - - YuzL-like protein
IELDDGJM_02985 2.44e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IELDDGJM_02986 2.23e-54 - - - - - - - -
IELDDGJM_02987 8.66e-70 yusN - - M - - - Coat F domain
IELDDGJM_02988 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
IELDDGJM_02989 0.0 yusP - - P - - - Major facilitator superfamily
IELDDGJM_02990 2.32e-82 yusQ - - S - - - Tautomerase enzyme
IELDDGJM_02994 5.89e-138 - - - L - - - IstB-like ATP binding protein
IELDDGJM_02995 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
IELDDGJM_02996 1.88e-299 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
IELDDGJM_02997 4.76e-261 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IELDDGJM_02998 9.86e-201 yitH - - K - - - Acetyltransferase (GNAT) domain
IELDDGJM_02999 2.95e-91 - - - S - - - Acetyltransferase (GNAT) domain
IELDDGJM_03000 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IELDDGJM_03001 4.29e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
IELDDGJM_03002 1.59e-203 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
IELDDGJM_03003 4.16e-122 - - - - - - - -
IELDDGJM_03004 7.89e-216 - - - - - - - -
IELDDGJM_03005 1.34e-126 - - - S - - - Sporulation delaying protein SdpA
IELDDGJM_03006 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
IELDDGJM_03007 7.44e-121 - - - - - - - -
IELDDGJM_03008 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
IELDDGJM_03009 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
IELDDGJM_03010 4.34e-200 yitS - - S - - - protein conserved in bacteria
IELDDGJM_03011 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IELDDGJM_03012 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
IELDDGJM_03013 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
IELDDGJM_03014 1.92e-08 - - - - - - - -
IELDDGJM_03015 1.07e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IELDDGJM_03016 1.02e-184 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IELDDGJM_03017 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
IELDDGJM_03018 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
IELDDGJM_03019 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
IELDDGJM_03020 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
IELDDGJM_03021 9.68e-251 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IELDDGJM_03022 2.89e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IELDDGJM_03023 2.56e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
IELDDGJM_03024 1.69e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
IELDDGJM_03025 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IELDDGJM_03026 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
IELDDGJM_03027 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IELDDGJM_03028 2.51e-39 yjzC - - S - - - YjzC-like protein
IELDDGJM_03029 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
IELDDGJM_03030 6.65e-180 yjaU - - I - - - carboxylic ester hydrolase activity
IELDDGJM_03031 8.29e-129 yjaV - - - - - - -
IELDDGJM_03033 1.14e-124 - - - L - - - Integrase
IELDDGJM_03034 1.92e-46 yoeD - - G - - - Helix-turn-helix domain
IELDDGJM_03035 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IELDDGJM_03036 1.45e-199 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_03037 1.15e-234 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IELDDGJM_03038 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IELDDGJM_03039 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
IELDDGJM_03040 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_03041 3.86e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IELDDGJM_03042 3.18e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IELDDGJM_03043 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IELDDGJM_03044 3.77e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IELDDGJM_03045 3.29e-52 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
IELDDGJM_03046 9.35e-160 yoxB - - - - - - -
IELDDGJM_03047 1.56e-120 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IELDDGJM_03048 1.11e-300 yoaB - - EGP - - - the major facilitator superfamily
IELDDGJM_03049 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
IELDDGJM_03050 5.81e-235 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IELDDGJM_03051 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IELDDGJM_03052 2.44e-265 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IELDDGJM_03053 5.67e-149 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
IELDDGJM_03054 2.29e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IELDDGJM_03055 2.29e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IELDDGJM_03056 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IELDDGJM_03057 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
IELDDGJM_03058 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IELDDGJM_03059 3.29e-144 ccpN - - K - - - CBS domain
IELDDGJM_03060 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
IELDDGJM_03061 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
IELDDGJM_03062 1.24e-185 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
IELDDGJM_03063 5.29e-27 - - - S - - - YqzL-like protein
IELDDGJM_03064 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IELDDGJM_03065 5.52e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IELDDGJM_03066 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
IELDDGJM_03067 1.75e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IELDDGJM_03068 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
IELDDGJM_03070 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
IELDDGJM_03071 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
IELDDGJM_03072 2.07e-60 yqfC - - S - - - sporulation protein YqfC
IELDDGJM_03073 3.13e-79 yqfB - - - - - - -
IELDDGJM_03074 4.35e-192 yqfA - - S - - - UPF0365 protein
IELDDGJM_03075 4.61e-291 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
IELDDGJM_03076 9.15e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
IELDDGJM_03077 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
IELDDGJM_03078 1.89e-200 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
IELDDGJM_03079 2.22e-277 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
IELDDGJM_03080 2.14e-233 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
IELDDGJM_03081 2.18e-83 cgeA - - - ko:K06319 - ko00000 -
IELDDGJM_03082 1.76e-58 cgeC - - - ko:K06321 - ko00000 -
IELDDGJM_03083 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
IELDDGJM_03084 3.98e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
IELDDGJM_03086 2.59e-312 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IELDDGJM_03088 3.16e-151 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IELDDGJM_03089 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
IELDDGJM_03090 1.24e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
IELDDGJM_03091 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
IELDDGJM_03092 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
IELDDGJM_03093 2.1e-49 yozE - - S - - - Belongs to the UPF0346 family
IELDDGJM_03094 7.44e-159 yodN - - - - - - -
IELDDGJM_03096 5.18e-34 yozD - - S - - - YozD-like protein
IELDDGJM_03097 2.23e-135 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
IELDDGJM_03098 3.35e-71 yodL - - S - - - YodL-like
IELDDGJM_03099 2.08e-12 - - - - - - - -
IELDDGJM_03100 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
IELDDGJM_03101 7.71e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
IELDDGJM_03102 4.86e-41 yodI - - - - - - -
IELDDGJM_03103 3.03e-166 yodH - - Q - - - Methyltransferase
IELDDGJM_03104 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IELDDGJM_03105 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IELDDGJM_03106 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
IELDDGJM_03107 1.18e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IELDDGJM_03108 3.61e-144 yahD - - S ko:K06999 - ko00000 Carboxylesterase
IELDDGJM_03109 9.14e-317 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
IELDDGJM_03110 3.02e-295 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IELDDGJM_03111 3.57e-114 ywaE - - K - - - Transcriptional regulator
IELDDGJM_03112 5.58e-54 ywaF - - S - - - Integral membrane protein
IELDDGJM_03113 4.95e-54 ywaF - - S - - - Integral membrane protein
IELDDGJM_03114 5.37e-216 gspA - - M - - - General stress
IELDDGJM_03115 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IELDDGJM_03116 4.15e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IELDDGJM_03117 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IELDDGJM_03118 3.5e-309 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IELDDGJM_03119 3.56e-161 ywbB - - S - - - Protein of unknown function (DUF2711)
IELDDGJM_03120 8.1e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
IELDDGJM_03121 9.42e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
IELDDGJM_03122 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
IELDDGJM_03123 1.18e-274 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
IELDDGJM_03124 1.21e-143 ywbG - - M - - - effector of murein hydrolase
IELDDGJM_03125 4.47e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IELDDGJM_03126 2.7e-203 ywbI - - K - - - Transcriptional regulator
IELDDGJM_03127 2.19e-183 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IELDDGJM_03128 1.43e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IELDDGJM_03129 8.05e-314 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
IELDDGJM_03130 2.94e-247 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
IELDDGJM_03131 3.61e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
IELDDGJM_03132 2.94e-210 yxxF - - EG - - - EamA-like transporter family
IELDDGJM_03133 0.0 wapA - - M - - - COG3209 Rhs family protein
IELDDGJM_03134 2.34e-21 - - - S - - - YxiJ-like protein
IELDDGJM_03135 8.76e-53 - - - S - - - Protein of unknown function (DUF2812)
IELDDGJM_03136 2.18e-69 - - - K - - - Transcriptional regulator PadR-like family
IELDDGJM_03137 1.08e-268 - - - E - - - GDSL-like Lipase/Acylhydrolase
IELDDGJM_03138 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IELDDGJM_03139 7.34e-290 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
IELDDGJM_03140 5.32e-143 - - - - - - - -
IELDDGJM_03141 3.14e-190 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IELDDGJM_03142 1.07e-184 bglS - - M - - - licheninase activity
IELDDGJM_03143 3.17e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IELDDGJM_03144 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IELDDGJM_03145 2.28e-63 yxiS - - - - - - -
IELDDGJM_03146 8.47e-133 - - - T - - - Domain of unknown function (DUF4163)
IELDDGJM_03147 5.75e-267 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IELDDGJM_03148 2.38e-250 yetN - - S - - - Protein of unknown function (DUF3900)
IELDDGJM_03149 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IELDDGJM_03150 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IELDDGJM_03151 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
IELDDGJM_03152 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
IELDDGJM_03153 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
IELDDGJM_03154 1.58e-282 yfnE - - S - - - Glycosyltransferase like family 2
IELDDGJM_03155 4.53e-241 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
IELDDGJM_03156 2.94e-266 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IELDDGJM_03157 3.69e-168 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IELDDGJM_03158 1.39e-311 yfnA - - E ko:K03294 - ko00000 amino acid
IELDDGJM_03159 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IELDDGJM_03160 9.89e-159 yfmS - - NT - - - chemotaxis protein
IELDDGJM_03161 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IELDDGJM_03162 3.09e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
IELDDGJM_03163 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
IELDDGJM_03164 1.03e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
IELDDGJM_03165 2.75e-31 - - - - - - - -
IELDDGJM_03166 1.03e-116 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IELDDGJM_03167 1.18e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IELDDGJM_03168 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
IELDDGJM_03169 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
IELDDGJM_03170 4.36e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IELDDGJM_03172 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
IELDDGJM_03173 6.11e-106 - - - S - - - Protein of unknown function (DUF2690)
IELDDGJM_03174 4.62e-29 yjfB - - S - - - Putative motility protein
IELDDGJM_03175 9.56e-212 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
IELDDGJM_03176 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
IELDDGJM_03177 4.08e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
IELDDGJM_03178 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
IELDDGJM_03179 9.24e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
IELDDGJM_03182 5.04e-87 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
IELDDGJM_03184 2.16e-282 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IELDDGJM_03185 4.15e-278 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IELDDGJM_03186 9.18e-41 - - - - - - - -
IELDDGJM_03187 1.54e-180 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IELDDGJM_03188 1.05e-154 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
IELDDGJM_03189 1.14e-174 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IELDDGJM_03190 1.81e-224 yjlA - - EG - - - Putative multidrug resistance efflux transporter
IELDDGJM_03191 2.87e-117 yjlB - - S - - - Cupin domain
IELDDGJM_03192 3.98e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
IELDDGJM_03193 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IELDDGJM_03194 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
IELDDGJM_03195 7.52e-315 - - - G ko:K03292 - ko00000 symporter YjmB
IELDDGJM_03196 2.08e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
IELDDGJM_03197 5.73e-240 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
IELDDGJM_03198 1.53e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
IELDDGJM_03199 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IELDDGJM_03200 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
IELDDGJM_03201 2.23e-234 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
IELDDGJM_03202 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
IELDDGJM_03203 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
IELDDGJM_03204 9.2e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
IELDDGJM_03205 2.71e-103 yjoA - - S - - - DinB family
IELDDGJM_03206 2.38e-311 VCP - - O - - - AAA domain (dynein-related subfamily)
IELDDGJM_03207 1.6e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IELDDGJM_03209 1.21e-53 - - - S - - - YCII-related domain
IELDDGJM_03210 1.26e-216 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IELDDGJM_03211 5.74e-80 yjqA - - S - - - Bacterial PH domain
IELDDGJM_03212 2.74e-139 yjqB - - S - - - Pfam:DUF867
IELDDGJM_03213 1.3e-203 yjqC - - P ko:K07217 - ko00000 Catalase
IELDDGJM_03214 1.79e-143 xkdA - - E - - - IrrE N-terminal-like domain
IELDDGJM_03215 8.21e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
IELDDGJM_03217 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
IELDDGJM_03218 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
IELDDGJM_03222 4.02e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IELDDGJM_03223 7.93e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
IELDDGJM_03224 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
IELDDGJM_03225 0.0 yqbA - - S - - - portal protein
IELDDGJM_03226 2.23e-173 xkdF3 - - L - - - Putative phage serine protease XkdF
IELDDGJM_03227 3.91e-217 xkdG - - S - - - Phage capsid family
IELDDGJM_03228 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
IELDDGJM_03229 2.49e-84 yqbH - - S - - - Domain of unknown function (DUF3599)
IELDDGJM_03230 3.12e-110 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
IELDDGJM_03231 8.25e-101 xkdJ - - - - - - -
IELDDGJM_03232 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
IELDDGJM_03233 1.21e-98 xkdM - - S - - - Phage tail tube protein
IELDDGJM_03234 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
IELDDGJM_03235 0.0 xkdO - - L - - - Transglycosylase SLT domain
IELDDGJM_03236 3.75e-39 xkdO - - L - - - Transglycosylase SLT domain
IELDDGJM_03237 1.77e-158 xkdP - - S - - - Lysin motif
IELDDGJM_03238 2.31e-232 xkdQ - - G - - - NLP P60 protein
IELDDGJM_03239 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
IELDDGJM_03240 1.97e-92 xkdS - - S - - - Protein of unknown function (DUF2634)
IELDDGJM_03241 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IELDDGJM_03242 9.63e-136 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
IELDDGJM_03243 4.43e-56 - - - - - - - -
IELDDGJM_03244 0.0 - - - - - - - -
IELDDGJM_03245 8.68e-74 xkdW - - S - - - XkdW protein
IELDDGJM_03246 1.28e-30 xkdX - - - - - - -
IELDDGJM_03247 2.57e-119 xepA - - - - - - -
IELDDGJM_03248 7.78e-38 xepA - - - - - - -
IELDDGJM_03249 7.71e-52 xhlA - - S - - - Haemolysin XhlA
IELDDGJM_03250 8.12e-53 xhlB - - S - - - SPP1 phage holin
IELDDGJM_03251 3.2e-209 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
IELDDGJM_03252 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
IELDDGJM_03253 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
IELDDGJM_03254 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
IELDDGJM_03255 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
IELDDGJM_03256 2.36e-305 steT - - E ko:K03294 - ko00000 amino acid
IELDDGJM_03257 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IELDDGJM_03258 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IELDDGJM_03259 5.21e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IELDDGJM_03261 1.92e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IELDDGJM_03262 3.2e-176 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
IELDDGJM_03263 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
IELDDGJM_03264 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IELDDGJM_03265 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IELDDGJM_03266 1.71e-239 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IELDDGJM_03267 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IELDDGJM_03269 2.75e-224 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
IELDDGJM_03270 3.08e-249 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IELDDGJM_03271 9.9e-208 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IELDDGJM_03272 1.4e-235 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IELDDGJM_03273 3.29e-260 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
IELDDGJM_03274 1.84e-72 ykgA - - E - - - Amidinotransferase
IELDDGJM_03275 6.06e-114 ykgA - - E - - - Amidinotransferase
IELDDGJM_03276 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
IELDDGJM_03277 2.84e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IELDDGJM_03278 5.45e-13 - - - - - - - -
IELDDGJM_03279 3.25e-166 ykjA - - S - - - Protein of unknown function (DUF421)
IELDDGJM_03280 9.11e-128 ykkA - - S - - - Protein of unknown function (DUF664)
IELDDGJM_03281 1.46e-127 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IELDDGJM_03282 7.34e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
IELDDGJM_03283 1.94e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
IELDDGJM_03284 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IELDDGJM_03285 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IELDDGJM_03286 6.52e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IELDDGJM_03288 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
IELDDGJM_03289 1.21e-98 ohrR - - K - - - COG1846 Transcriptional regulators
IELDDGJM_03290 2.34e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
IELDDGJM_03291 2.06e-108 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
IELDDGJM_03292 1.17e-128 - - - G - - - Belongs to the phosphoglycerate mutase family
IELDDGJM_03293 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IELDDGJM_03294 4.27e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IELDDGJM_03295 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IELDDGJM_03296 3.65e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
IELDDGJM_03297 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_03298 2.81e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
IELDDGJM_03299 2.01e-141 ykoF - - S - - - YKOF-related Family
IELDDGJM_03300 4.3e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IELDDGJM_03301 1.42e-305 ykoH - - T - - - Histidine kinase
IELDDGJM_03302 3.74e-143 ykoI - - S - - - Peptidase propeptide and YPEB domain
IELDDGJM_03303 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
IELDDGJM_03304 1.45e-08 - - - - - - - -
IELDDGJM_03306 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
IELDDGJM_03307 1.49e-70 tnrA - - K - - - transcriptional
IELDDGJM_03308 1.63e-25 - - - - - - - -
IELDDGJM_03309 3.04e-36 ykoL - - - - - - -
IELDDGJM_03310 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
IELDDGJM_03311 1.76e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
IELDDGJM_03312 2.07e-126 ykoP - - G - - - polysaccharide deacetylase
IELDDGJM_03313 7.22e-197 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
IELDDGJM_03314 0.0 ykoS - - - - - - -
IELDDGJM_03315 2.23e-236 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
IELDDGJM_03316 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
IELDDGJM_03317 7.24e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IELDDGJM_03318 1.41e-69 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
IELDDGJM_03319 1.89e-31 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
IELDDGJM_03320 3.75e-131 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
IELDDGJM_03321 2.46e-74 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
IELDDGJM_03322 1.67e-77 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
IELDDGJM_03323 1.71e-143 ykoX - - S - - - membrane-associated protein
IELDDGJM_03324 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IELDDGJM_03325 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IELDDGJM_03326 1.41e-199 rsgI - - S - - - Anti-sigma factor N-terminus
IELDDGJM_03327 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
IELDDGJM_03328 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
IELDDGJM_03329 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
IELDDGJM_03330 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
IELDDGJM_03332 1.77e-28 ykzE - - - - - - -
IELDDGJM_03333 3.2e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
IELDDGJM_03334 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_03335 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IELDDGJM_03337 1.55e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IELDDGJM_03338 1e-292 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IELDDGJM_03339 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IELDDGJM_03340 2.67e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IELDDGJM_03341 1.38e-294 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IELDDGJM_03342 2.06e-174 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IELDDGJM_03343 2.15e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IELDDGJM_03344 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IELDDGJM_03345 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
IELDDGJM_03347 7.98e-93 eag - - - - - - -
IELDDGJM_03348 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IELDDGJM_03349 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
IELDDGJM_03350 3.69e-163 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IELDDGJM_03351 9.19e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IELDDGJM_03352 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
IELDDGJM_03353 3.91e-226 ykvI - - S - - - membrane
IELDDGJM_03354 5.28e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IELDDGJM_03355 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
IELDDGJM_03356 3.42e-177 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IELDDGJM_03357 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IELDDGJM_03358 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IELDDGJM_03359 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IELDDGJM_03360 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
IELDDGJM_03361 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
IELDDGJM_03362 2.14e-36 yteV - - S - - - Sporulation protein Cse60
IELDDGJM_03363 3.81e-150 yteU - - S - - - Integral membrane protein
IELDDGJM_03364 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
IELDDGJM_03365 7.92e-93 yteS - - G - - - transport
IELDDGJM_03366 2.9e-279 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
IELDDGJM_03367 5.35e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
IELDDGJM_03368 1.36e-202 ytdP - - K - - - Transcriptional regulator
IELDDGJM_03369 2.74e-276 ytdP - - K - - - Transcriptional regulator
IELDDGJM_03370 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
IELDDGJM_03371 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
IELDDGJM_03372 9.01e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
IELDDGJM_03373 2.6e-278 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IELDDGJM_03374 1.86e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IELDDGJM_03375 6.59e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IELDDGJM_03376 1.05e-274 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IELDDGJM_03377 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IELDDGJM_03378 7.51e-191 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IELDDGJM_03379 1.24e-77 ywnC - - S - - - Family of unknown function (DUF5362)
IELDDGJM_03380 1.62e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
IELDDGJM_03381 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IELDDGJM_03382 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
IELDDGJM_03383 2.01e-17 ywnC - - S - - - Family of unknown function (DUF5362)
IELDDGJM_03384 1.49e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
IELDDGJM_03385 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IELDDGJM_03386 3.84e-94 ywnJ - - S - - - VanZ like family
IELDDGJM_03387 1.72e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
IELDDGJM_03388 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
IELDDGJM_03389 1.53e-286 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
IELDDGJM_03390 2.12e-16 - - - - - - - -
IELDDGJM_03391 1.12e-74 - - - - - - - -
IELDDGJM_03392 2.56e-134 yjgF - - Q - - - Isochorismatase family
IELDDGJM_03393 3.63e-305 ywoD - - EGP - - - Major facilitator superfamily
IELDDGJM_03394 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
IELDDGJM_03395 4.42e-307 ywoF - - P - - - Right handed beta helix region
IELDDGJM_03396 1.31e-267 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IELDDGJM_03397 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
IELDDGJM_03398 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
IELDDGJM_03399 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
IELDDGJM_03400 1.14e-168 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IELDDGJM_03401 3.23e-179 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IELDDGJM_03402 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
IELDDGJM_03403 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IELDDGJM_03404 3.25e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IELDDGJM_03405 1.31e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IELDDGJM_03406 5.24e-101 ydaG - - S - - - general stress protein
IELDDGJM_03407 1.28e-131 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IELDDGJM_03408 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
IELDDGJM_03409 3.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IELDDGJM_03410 6.78e-126 ydaC - - Q - - - Methyltransferase domain
IELDDGJM_03411 0.0 ydaB - - IQ - - - acyl-CoA ligase
IELDDGJM_03412 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
IELDDGJM_03413 3.5e-219 ycsN - - S - - - Oxidoreductase
IELDDGJM_03414 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
IELDDGJM_03415 7.67e-66 yczJ - - S - - - biosynthesis
IELDDGJM_03417 2.71e-150 ycsK - - E - - - anatomical structure formation involved in morphogenesis
IELDDGJM_03418 6.3e-170 kipR - - K - - - Transcriptional regulator
IELDDGJM_03419 9.08e-235 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
IELDDGJM_03420 2.92e-172 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
IELDDGJM_03421 1.36e-187 ycsI - - S - - - Belongs to the D-glutamate cyclase family
IELDDGJM_03422 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
IELDDGJM_03423 3.82e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
IELDDGJM_03424 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IELDDGJM_03426 6.58e-101 yoaW - - - - - - -
IELDDGJM_03427 4.14e-198 yoaV - - EG - - - EamA-like transporter family
IELDDGJM_03428 4.16e-201 yoaU - - K - - - LysR substrate binding domain
IELDDGJM_03429 7.76e-189 yoaT - - S - - - Protein of unknown function (DUF817)
IELDDGJM_03430 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_03431 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
IELDDGJM_03432 5.54e-213 yoaR - - V - - - vancomycin resistance protein
IELDDGJM_03433 2.01e-108 - - - - - - - -
IELDDGJM_03436 1.04e-63 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IELDDGJM_03437 1.45e-207 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IELDDGJM_03440 6.39e-165 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
IELDDGJM_03441 4.93e-71 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
IELDDGJM_03442 6.36e-129 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
IELDDGJM_03443 1.79e-145 yoaK - - S - - - Membrane
IELDDGJM_03444 4.33e-170 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
IELDDGJM_03445 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
IELDDGJM_03446 4.02e-288 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
IELDDGJM_03447 6.14e-19 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
IELDDGJM_03448 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
IELDDGJM_03449 1.46e-19 - - - - - - - -
IELDDGJM_03451 3.58e-119 yfhK - - T - - - Bacterial SH3 domain homologues
IELDDGJM_03452 1.81e-65 yfhL - - S - - - SdpI/YhfL protein family
IELDDGJM_03453 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
IELDDGJM_03454 2.32e-234 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IELDDGJM_03455 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
IELDDGJM_03456 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
IELDDGJM_03457 2.26e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
IELDDGJM_03458 1.73e-48 yfhS - - - - - - -
IELDDGJM_03459 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IELDDGJM_03460 9.51e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
IELDDGJM_03461 1.88e-63 ygaB - - S - - - YgaB-like protein
IELDDGJM_03462 1.64e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
IELDDGJM_03463 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
IELDDGJM_03464 3.61e-236 ygaE - - S - - - Membrane
IELDDGJM_03465 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IELDDGJM_03466 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
IELDDGJM_03467 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
IELDDGJM_03468 5.46e-74 ygzB - - S - - - UPF0295 protein
IELDDGJM_03469 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
IELDDGJM_03470 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IELDDGJM_03471 4.41e-222 yhbB - - S - - - Putative amidase domain
IELDDGJM_03472 4.88e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IELDDGJM_03473 1.92e-147 yhzB - - S - - - B3/4 domain
IELDDGJM_03475 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_03476 5.41e-100 ygaO - - - - - - -
IELDDGJM_03477 1.96e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IELDDGJM_03479 3.13e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
IELDDGJM_03480 2.39e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IELDDGJM_03481 2.08e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
IELDDGJM_03482 8.37e-185 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IELDDGJM_03483 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IELDDGJM_03485 0.0 ygaK - - C - - - Berberine and berberine like
IELDDGJM_03486 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IELDDGJM_03487 1.29e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
IELDDGJM_03488 1.58e-36 - - - - - - - -
IELDDGJM_03489 1.5e-183 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
IELDDGJM_03490 1.94e-145 tetR3 - - K ko:K18476 - ko00000,ko00002,ko03000 Transcriptional regulator
IELDDGJM_03491 5.17e-149 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 Multidrug transporter MatE
IELDDGJM_03492 2.08e-87 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 Multidrug transporter MatE
IELDDGJM_03493 1.03e-206 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
IELDDGJM_03494 7.04e-155 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
IELDDGJM_03495 3.74e-48 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
IELDDGJM_03496 1.2e-262 yrkH - - P - - - Rhodanese Homology Domain
IELDDGJM_03497 0.000112 perX - - S - - - DsrE/DsrF-like family
IELDDGJM_03498 4.61e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
IELDDGJM_03499 1.96e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
IELDDGJM_03500 4.38e-52 yrkD - - S - - - protein conserved in bacteria
IELDDGJM_03501 3.32e-28 - - - - - - - -
IELDDGJM_03502 4.11e-134 yrkC - - G - - - Cupin domain
IELDDGJM_03503 1.45e-193 bltR - - K - - - helix_turn_helix, mercury resistance
IELDDGJM_03504 1.18e-213 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IELDDGJM_03505 3.58e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
IELDDGJM_03506 7.52e-300 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IELDDGJM_03507 7.04e-23 - - - S - - - YrzO-like protein
IELDDGJM_03508 1.54e-79 yrdR - - EG - - - EamA-like transporter family
IELDDGJM_03509 4.17e-97 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
IELDDGJM_03510 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
IELDDGJM_03511 2.39e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
IELDDGJM_03512 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
IELDDGJM_03513 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
IELDDGJM_03514 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
IELDDGJM_03515 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IELDDGJM_03516 1.15e-43 ynzC - - S - - - UPF0291 protein
IELDDGJM_03517 2.68e-143 yneB - - L - - - resolvase
IELDDGJM_03518 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IELDDGJM_03519 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IELDDGJM_03520 3.01e-102 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IELDDGJM_03521 4.11e-117 yndM - - S - - - Protein of unknown function (DUF2512)
IELDDGJM_03522 1.27e-172 yndL - - S - - - Replication protein
IELDDGJM_03524 0.0 yndJ - - S - - - YndJ-like protein
IELDDGJM_03525 2.36e-146 - - - S - - - Domain of unknown function (DUF4166)
IELDDGJM_03526 5.29e-198 yndG - - S - - - DoxX-like family
IELDDGJM_03527 6.51e-241 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
IELDDGJM_03528 2.72e-210 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
IELDDGJM_03531 7.94e-22 ydhU - - P ko:K07217 - ko00000 Manganese containing catalase
IELDDGJM_03532 4.79e-100 ydhU - - P ko:K07217 - ko00000 Catalase
IELDDGJM_03533 3.08e-267 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
IELDDGJM_03534 1.2e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IELDDGJM_03535 9.56e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
IELDDGJM_03536 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
IELDDGJM_03537 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IELDDGJM_03538 2.27e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IELDDGJM_03539 1.44e-68 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IELDDGJM_03540 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IELDDGJM_03541 2.56e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
IELDDGJM_03542 5.69e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
IELDDGJM_03543 1.28e-229 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
IELDDGJM_03544 6.55e-109 - - - K - - - Acetyltransferase (GNAT) domain
IELDDGJM_03546 1.12e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IELDDGJM_03547 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
IELDDGJM_03548 1.37e-159 - - - - - - - -
IELDDGJM_03549 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IELDDGJM_03550 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
IELDDGJM_03551 7.38e-121 yobW - - - - - - -
IELDDGJM_03552 8.97e-224 yobV - - K - - - WYL domain
IELDDGJM_03553 1.43e-110 - - - K - - - Bacterial transcription activator, effector binding domain
IELDDGJM_03554 3.16e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IELDDGJM_03555 3.09e-127 yobS - - K - - - Transcriptional regulator
IELDDGJM_03556 2.06e-180 - - - J - - - FR47-like protein
IELDDGJM_03557 2.91e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
IELDDGJM_03558 8.66e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
IELDDGJM_03559 2.76e-283 yobO - - M - - - Pectate lyase superfamily protein
IELDDGJM_03560 3.89e-248 yobO - - M - - - Pectate lyase superfamily protein
IELDDGJM_03561 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
IELDDGJM_03562 1.14e-131 yokH - - G - - - SMI1 / KNR4 family
IELDDGJM_03563 0.0 - - - UW ko:K21487,ko:K21489,ko:K21491,ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
IELDDGJM_03564 9.26e-123 - - - S ko:K21490 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
IELDDGJM_03565 2.21e-104 yokK - - S - - - SMI1 / KNR4 family
IELDDGJM_03566 4.92e-139 lin0465 - - S - - - DJ-1/PfpI family
IELDDGJM_03567 5.98e-285 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IELDDGJM_03568 1.58e-239 ysoA - - H - - - Tetratricopeptide repeat
IELDDGJM_03569 1.26e-148 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IELDDGJM_03570 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IELDDGJM_03571 6.1e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IELDDGJM_03572 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IELDDGJM_03573 2.26e-243 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IELDDGJM_03574 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IELDDGJM_03575 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IELDDGJM_03577 1.25e-102 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
IELDDGJM_03578 9.64e-183 ysnF - - S - - - protein conserved in bacteria
IELDDGJM_03580 1.65e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
IELDDGJM_03581 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IELDDGJM_03582 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IELDDGJM_03583 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
IELDDGJM_03584 3.55e-195 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IELDDGJM_03585 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
IELDDGJM_03586 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_03587 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
IELDDGJM_03588 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IELDDGJM_03589 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IELDDGJM_03590 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
IELDDGJM_03591 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
IELDDGJM_03592 2.67e-273 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IELDDGJM_03593 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IELDDGJM_03594 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
IELDDGJM_03595 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
IELDDGJM_03597 1.18e-225 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
IELDDGJM_03598 1.74e-177 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
IELDDGJM_03599 1.81e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
IELDDGJM_03600 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_03601 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IELDDGJM_03602 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
IELDDGJM_03603 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IELDDGJM_03604 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
IELDDGJM_03605 1.55e-111 yshB - - S - - - membrane protein, required for colicin V production
IELDDGJM_03606 2.45e-53 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IELDDGJM_03607 1.47e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IELDDGJM_03608 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IELDDGJM_03609 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IELDDGJM_03610 7.37e-170 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IELDDGJM_03611 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
IELDDGJM_03612 1.24e-260 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
IELDDGJM_03613 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
IELDDGJM_03614 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
IELDDGJM_03615 1.79e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
IELDDGJM_03616 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
IELDDGJM_03617 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
IELDDGJM_03618 4.28e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
IELDDGJM_03619 7.9e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
IELDDGJM_03620 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
IELDDGJM_03621 1.24e-280 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IELDDGJM_03622 7.07e-186 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
IELDDGJM_03623 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IELDDGJM_03624 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
IELDDGJM_03625 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
IELDDGJM_03626 6.22e-239 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IELDDGJM_03627 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
IELDDGJM_03628 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
IELDDGJM_03629 3.65e-59 ysdA - - S - - - Membrane
IELDDGJM_03630 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IELDDGJM_03631 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
IELDDGJM_03632 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IELDDGJM_03634 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IELDDGJM_03635 2e-83 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IELDDGJM_03636 9.71e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
IELDDGJM_03637 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_03638 4.68e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
IELDDGJM_03639 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IELDDGJM_03641 5.74e-204 ytxC - - S - - - YtxC-like family
IELDDGJM_03642 3.66e-139 ytxB - - S - - - SNARE associated Golgi protein
IELDDGJM_03643 2.46e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
IELDDGJM_03644 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
IELDDGJM_03645 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IELDDGJM_03646 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IELDDGJM_03647 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IELDDGJM_03648 9.85e-88 ytcD - - K - - - Transcriptional regulator
IELDDGJM_03649 1.82e-258 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
IELDDGJM_03650 2.16e-203 ytbE - - S - - - reductase
IELDDGJM_03651 8.07e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IELDDGJM_03652 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
IELDDGJM_03653 2.73e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IELDDGJM_03654 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IELDDGJM_03655 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
IELDDGJM_03656 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IELDDGJM_03657 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
IELDDGJM_03658 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
IELDDGJM_03659 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IELDDGJM_03660 9.38e-95 ytwI - - S - - - membrane
IELDDGJM_03661 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
IELDDGJM_03662 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
IELDDGJM_03663 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
IELDDGJM_03664 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IELDDGJM_03665 5.68e-233 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IELDDGJM_03666 1.25e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IELDDGJM_03667 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IELDDGJM_03668 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
IELDDGJM_03669 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
IELDDGJM_03670 5.12e-112 ytrI - - - - - - -
IELDDGJM_03671 1.15e-39 - - - - - - - -
IELDDGJM_03672 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
IELDDGJM_03673 2.15e-63 ytpI - - S - - - YtpI-like protein
IELDDGJM_03674 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
IELDDGJM_03675 8.36e-202 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
IELDDGJM_03676 5.44e-235 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
IELDDGJM_03677 1.98e-165 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
IELDDGJM_03678 1.07e-242 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IELDDGJM_03679 9.28e-55 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IELDDGJM_03680 1.7e-59 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
IELDDGJM_03681 1.98e-233 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IELDDGJM_03682 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IELDDGJM_03683 4.76e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IELDDGJM_03684 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IELDDGJM_03685 7.63e-188 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IELDDGJM_03686 9.11e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IELDDGJM_03687 3.42e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IELDDGJM_03688 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
IELDDGJM_03689 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
IELDDGJM_03690 8.04e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IELDDGJM_03692 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
IELDDGJM_03693 3.03e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
IELDDGJM_03694 2.62e-111 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
IELDDGJM_03695 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IELDDGJM_03696 2e-219 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
IELDDGJM_03697 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IELDDGJM_03698 1.84e-95 ytfJ - - S - - - Sporulation protein YtfJ
IELDDGJM_03699 5.16e-143 ytfI - - S - - - Protein of unknown function (DUF2953)
IELDDGJM_03700 8.23e-112 yteJ - - S - - - RDD family
IELDDGJM_03701 2.79e-229 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
IELDDGJM_03702 4.65e-187 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IELDDGJM_03703 0.0 ytcJ - - S - - - amidohydrolase
IELDDGJM_03704 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IELDDGJM_03705 7.14e-39 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
IELDDGJM_03706 2.55e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IELDDGJM_03707 8.21e-268 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IELDDGJM_03708 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IELDDGJM_03709 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IELDDGJM_03710 2.16e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IELDDGJM_03711 1.2e-141 yttP - - K - - - Transcriptional regulator
IELDDGJM_03712 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
IELDDGJM_03713 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
IELDDGJM_03714 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IELDDGJM_03715 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
IELDDGJM_03716 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
IELDDGJM_03717 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IELDDGJM_03718 1.77e-54 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IELDDGJM_03719 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IELDDGJM_03720 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IELDDGJM_03721 2.3e-124 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
IELDDGJM_03722 2.74e-271 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
IELDDGJM_03723 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
IELDDGJM_03724 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
IELDDGJM_03726 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IELDDGJM_03727 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IELDDGJM_03728 5.26e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IELDDGJM_03729 1.24e-314 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IELDDGJM_03730 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IELDDGJM_03731 2.45e-230 yaaC - - S - - - YaaC-like Protein
IELDDGJM_03732 1.67e-221 - - - S - - - Acetyl xylan esterase (AXE1)
IELDDGJM_03733 2.08e-240 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IELDDGJM_03734 8.26e-309 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IELDDGJM_03735 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IELDDGJM_03736 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IELDDGJM_03737 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
IELDDGJM_03738 1.22e-68 ytwF - - P - - - Sulfurtransferase
IELDDGJM_03739 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
IELDDGJM_03740 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
IELDDGJM_03741 5.43e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IELDDGJM_03742 4.94e-268 yttB - - EGP - - - Major facilitator superfamily
IELDDGJM_03743 9.37e-77 yttA - - S - - - Pfam Transposase IS66
IELDDGJM_03744 1.24e-55 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
IELDDGJM_03746 1.75e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
IELDDGJM_03747 1.12e-154 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IELDDGJM_03748 5.11e-161 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
IELDDGJM_03749 3.6e-25 - - - - - - - -
IELDDGJM_03750 0.0 ywqB - - S - - - SWIM zinc finger
IELDDGJM_03751 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IELDDGJM_03752 3.72e-202 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IELDDGJM_03753 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IELDDGJM_03754 2.45e-75 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
IELDDGJM_03755 3.04e-87 ywpG - - - - - - -
IELDDGJM_03756 8.81e-89 ywpF - - S - - - YwpF-like protein
IELDDGJM_03757 3.14e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
IELDDGJM_03758 7.72e-185 ywpD - - T - - - Histidine kinase
IELDDGJM_03759 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
IELDDGJM_03760 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IELDDGJM_03761 3.04e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IELDDGJM_03762 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IELDDGJM_03763 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IELDDGJM_03764 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
IELDDGJM_03765 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
IELDDGJM_03766 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IELDDGJM_03767 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IELDDGJM_03768 3.15e-181 - - - L - - - Belongs to the 'phage' integrase family
IELDDGJM_03769 1.35e-61 xkdA - - E - - - IrrE N-terminal-like domain
IELDDGJM_03771 1.6e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
IELDDGJM_03772 7.9e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
IELDDGJM_03773 6.84e-48 - - - - - - - -
IELDDGJM_03774 2.09e-49 - - - S - - - DNA binding
IELDDGJM_03775 4.08e-106 - - - - - - - -
IELDDGJM_03779 5.01e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IELDDGJM_03780 8.71e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
IELDDGJM_03781 2.91e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IELDDGJM_03782 7.63e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IELDDGJM_03783 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
IELDDGJM_03784 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IELDDGJM_03785 8.23e-117 ysxD - - - - - - -
IELDDGJM_03786 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
IELDDGJM_03787 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IELDDGJM_03788 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
IELDDGJM_03789 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IELDDGJM_03790 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IELDDGJM_03791 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IELDDGJM_03792 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IELDDGJM_03793 8.5e-48 ydaS - - S - - - membrane
IELDDGJM_03794 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IELDDGJM_03795 5.34e-289 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IELDDGJM_03796 3.33e-77 gtcA - - S - - - GtrA-like protein
IELDDGJM_03797 4.66e-156 ywcC - - K - - - transcriptional regulator
IELDDGJM_03799 8.67e-64 ywcB - - S - - - Protein of unknown function, DUF485
IELDDGJM_03800 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IELDDGJM_03801 3.14e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IELDDGJM_03802 1.45e-53 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
IELDDGJM_03803 2.85e-88 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IELDDGJM_03806 8.04e-96 - - - J - - - Acetyltransferase (GNAT) domain
IELDDGJM_03808 8.87e-62 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IELDDGJM_03809 5.56e-188 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IELDDGJM_03810 1.74e-43 - - - M - - - nucleic acid phosphodiester bond hydrolysis
IELDDGJM_03813 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
IELDDGJM_03814 2.19e-55 - - - - - - - -
IELDDGJM_03816 6.91e-77 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
IELDDGJM_03817 2.53e-74 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
IELDDGJM_03818 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
IELDDGJM_03819 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IELDDGJM_03820 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
IELDDGJM_03821 3.31e-52 yubF - - S - - - yiaA/B two helix domain
IELDDGJM_03822 4.49e-197 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IELDDGJM_03823 0.0 yubD - - P - - - Major Facilitator Superfamily
IELDDGJM_03824 3.95e-113 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
IELDDGJM_03829 1.31e-28 - - - K - - - Cro/C1-type HTH DNA-binding domain
IELDDGJM_03831 3.75e-13 - - - - - - - -
IELDDGJM_03834 1.42e-09 - - - S - - - YolD-like protein
IELDDGJM_03835 1.92e-47 - - - - - - - -
IELDDGJM_03836 2.77e-26 - - - - - - - -
IELDDGJM_03837 1.72e-23 - - - - - - - -
IELDDGJM_03838 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
IELDDGJM_03839 1.78e-60 yjcN - - - - - - -
IELDDGJM_03840 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
IELDDGJM_03841 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IELDDGJM_03842 9.08e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IELDDGJM_03843 5.34e-75 yjdF3 - - S - - - Protein of unknown function (DUF2992)
IELDDGJM_03844 1.56e-08 - - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
IELDDGJM_03845 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IELDDGJM_03846 2.34e-203 ybaS - - S - - - Na -dependent transporter
IELDDGJM_03847 2.71e-182 ybbA - - S ko:K07017 - ko00000 Putative esterase
IELDDGJM_03848 4.99e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IELDDGJM_03849 4.77e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IELDDGJM_03850 5.12e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
IELDDGJM_03851 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
IELDDGJM_03852 1.92e-301 ybbC - - S - - - protein conserved in bacteria
IELDDGJM_03853 2.88e-58 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
IELDDGJM_03854 4.01e-161 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IELDDGJM_03855 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
IELDDGJM_03856 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
IELDDGJM_03857 5.44e-74 yuzD - - S - - - protein conserved in bacteria
IELDDGJM_03858 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IELDDGJM_03859 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
IELDDGJM_03860 2.97e-268 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IELDDGJM_03861 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IELDDGJM_03862 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
IELDDGJM_03863 1.39e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IELDDGJM_03864 6.43e-146 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
IELDDGJM_03865 1.29e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IELDDGJM_03867 5.51e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
IELDDGJM_03868 6.9e-300 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IELDDGJM_03869 1.14e-45 yuiB - - S - - - Putative membrane protein
IELDDGJM_03870 6.61e-149 yuiC - - S - - - protein conserved in bacteria
IELDDGJM_03871 7.09e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
IELDDGJM_03872 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IELDDGJM_03873 2.46e-277 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
IELDDGJM_03874 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
IELDDGJM_03875 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
IELDDGJM_03876 8.94e-213 eSD - - S ko:K07017 - ko00000 Putative esterase
IELDDGJM_03877 1.95e-176 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IELDDGJM_03878 3.34e-287 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IELDDGJM_03879 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
IELDDGJM_03880 1.5e-226 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
IELDDGJM_03881 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IELDDGJM_03882 1.66e-46 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
IELDDGJM_03883 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
IELDDGJM_03884 5.47e-260 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
IELDDGJM_03885 4.03e-290 yukF - - QT - - - Transcriptional regulator
IELDDGJM_03886 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
IELDDGJM_03887 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
IELDDGJM_03888 5.18e-270 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
IELDDGJM_03889 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IELDDGJM_03890 0.0 yueB - - S - - - type VII secretion protein EsaA
IELDDGJM_03891 4.37e-97 yueC - - S - - - Family of unknown function (DUF5383)
IELDDGJM_03892 1.96e-167 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IELDDGJM_03893 3.85e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
IELDDGJM_03894 3.42e-32 - - - S - - - Protein of unknown function (DUF2642)
IELDDGJM_03895 1.01e-86 - - - S - - - Protein of unknown function (DUF2283)
IELDDGJM_03896 6.42e-243 yueF - - S - - - transporter activity
IELDDGJM_03897 1.19e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
IELDDGJM_03898 1.34e-51 yueH - - S - - - YueH-like protein
IELDDGJM_03899 5.37e-88 - - - S - - - Protein of unknown function (DUF1694)
IELDDGJM_03900 3.82e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
IELDDGJM_03901 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IELDDGJM_03902 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
IELDDGJM_03903 8.73e-09 yuzC - - - - - - -
IELDDGJM_03904 6.29e-10 - - - S - - - DegQ (SacQ) family
IELDDGJM_03905 3.33e-168 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
IELDDGJM_03907 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_03908 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IELDDGJM_03909 2.72e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
IELDDGJM_03910 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
IELDDGJM_03911 2.61e-50 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IELDDGJM_03912 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IELDDGJM_03913 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IELDDGJM_03914 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IELDDGJM_03915 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IELDDGJM_03916 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IELDDGJM_03917 1.73e-22 - - - - - - - -
IELDDGJM_03918 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
IELDDGJM_03919 4.9e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IELDDGJM_03920 2.6e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IELDDGJM_03921 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IELDDGJM_03922 6.9e-160 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
IELDDGJM_03923 5.68e-79 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
IELDDGJM_03924 1.88e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IELDDGJM_03925 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IELDDGJM_03926 1.71e-112 yufK - - S - - - Family of unknown function (DUF5366)
IELDDGJM_03927 1.92e-97 yuxK - - S - - - protein conserved in bacteria
IELDDGJM_03928 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
IELDDGJM_03929 8.9e-242 yuxJ - - EGP - - - Major facilitator superfamily
IELDDGJM_03931 1.41e-148 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
IELDDGJM_03932 4.84e-89 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
IELDDGJM_03933 6.13e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IELDDGJM_03934 1.16e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IELDDGJM_03935 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
IELDDGJM_03936 9.89e-201 yugF - - I - - - Hydrolase
IELDDGJM_03937 6.74e-112 alaR - - K - - - Transcriptional regulator
IELDDGJM_03938 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
IELDDGJM_03939 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IELDDGJM_03940 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
IELDDGJM_03941 8.16e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
IELDDGJM_03942 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
IELDDGJM_03943 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
IELDDGJM_03945 1.41e-88 yugN - - S - - - YugN-like family
IELDDGJM_03946 1.69e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
IELDDGJM_03947 1.01e-68 mstX - - S - - - Membrane-integrating protein Mistic
IELDDGJM_03948 2.16e-48 - - - - - - - -
IELDDGJM_03949 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
IELDDGJM_03950 1.03e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IELDDGJM_03951 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IELDDGJM_03952 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
IELDDGJM_03953 5e-48 - - - - - - - -
IELDDGJM_03954 4.16e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IELDDGJM_03955 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IELDDGJM_03956 3.19e-120 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IELDDGJM_03957 1.31e-113 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IELDDGJM_03958 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IELDDGJM_03959 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IELDDGJM_03960 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
IELDDGJM_03961 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IELDDGJM_03962 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IELDDGJM_03963 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
IELDDGJM_03964 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
IELDDGJM_03965 3.71e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IELDDGJM_03966 1.73e-252 yubA - - S - - - transporter activity
IELDDGJM_03967 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IELDDGJM_03969 9.2e-73 - - - L - - - Arm DNA-binding domain
IELDDGJM_03970 1.64e-29 - - - K - - - Helix-turn-helix XRE-family like proteins
IELDDGJM_03972 2.62e-80 - - - - - - - -
IELDDGJM_03977 3.99e-126 - - - - - - - -
IELDDGJM_03978 4.62e-201 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
IELDDGJM_03980 1.77e-137 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IELDDGJM_03981 8.03e-138 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IELDDGJM_03982 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
IELDDGJM_03983 3.65e-173 azlC - - E - - - AzlC protein
IELDDGJM_03984 6.68e-72 bkdR - - K - - - helix_turn_helix ASNC type
IELDDGJM_03985 7.91e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
IELDDGJM_03986 7.64e-290 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IELDDGJM_03988 4.27e-132 yrdC - - Q - - - Isochorismatase family
IELDDGJM_03989 2.28e-75 - - - S - - - Protein of unknown function (DUF2568)
IELDDGJM_03991 5.77e-118 yrdA - - S - - - DinB family
IELDDGJM_03992 4.94e-211 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
IELDDGJM_03993 5.15e-247 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IELDDGJM_03994 8.38e-189 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IELDDGJM_03995 2.29e-160 yrpD - - S - - - Domain of unknown function, YrpD
IELDDGJM_03997 6.47e-99 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IELDDGJM_03998 1.65e-43 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IELDDGJM_03999 1.39e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IELDDGJM_04000 2.43e-239 yrpG - - C - - - Aldo/keto reductase family
IELDDGJM_04001 9.19e-287 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IELDDGJM_04002 5.83e-118 yuaB - - - - - - -
IELDDGJM_04003 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
IELDDGJM_04004 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IELDDGJM_04005 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
IELDDGJM_04006 6.78e-136 yuaD - - - - - - -
IELDDGJM_04007 1.95e-109 yuaE - - S - - - DinB superfamily
IELDDGJM_04008 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
IELDDGJM_04009 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
IELDDGJM_04010 1.2e-122 - - - M - - - FR47-like protein
IELDDGJM_04011 3.58e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
IELDDGJM_04012 5.02e-262 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IELDDGJM_04013 3.6e-226 - - - L - - - Replication protein
IELDDGJM_04016 7.23e-99 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Hsp20/alpha crystallin family
IELDDGJM_04017 2.81e-301 pre - - D - - - plasmid recombination enzyme
IELDDGJM_04018 6.29e-100 - - - K - - - Transcriptional regulator
IELDDGJM_04020 1.08e-135 rapE - - S ko:K06363 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
IELDDGJM_04022 1.57e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
IELDDGJM_04023 2.96e-178 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IELDDGJM_04024 1.77e-32 yqzJ - - - - - - -
IELDDGJM_04025 4.32e-298 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IELDDGJM_04026 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IELDDGJM_04027 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IELDDGJM_04028 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IELDDGJM_04029 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IELDDGJM_04031 5.15e-81 - - - - - - - -
IELDDGJM_04033 2.24e-41 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
IELDDGJM_04034 3.18e-204 - - - S - - - Calcineurin-like phosphoesterase
IELDDGJM_04040 2.22e-40 - - - S - - - Macro domain
IELDDGJM_04043 3.77e-137 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IELDDGJM_04045 2.29e-19 - - - V - - - VanZ like family
IELDDGJM_04046 1.22e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
IELDDGJM_04048 2.56e-57 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IELDDGJM_04049 2.71e-52 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IELDDGJM_04050 3.53e-75 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IELDDGJM_04052 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IELDDGJM_04053 1.07e-302 yokA - - L - - - Recombinase
IELDDGJM_04055 3.21e-104 - - - S ko:K03824 - ko00000,ko01000 family acetyltransferase
IELDDGJM_04056 6.77e-167 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
IELDDGJM_04057 3.28e-48 - - - - - - - -
IELDDGJM_04058 3.05e-86 - - - G - - - SMI1-KNR4 cell-wall
IELDDGJM_04059 2.97e-210 yraN - - K - - - Transcriptional regulator
IELDDGJM_04060 1.71e-262 yraM - - S - - - PrpF protein
IELDDGJM_04061 4.54e-19 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IELDDGJM_04062 9.4e-51 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IELDDGJM_04063 2.15e-194 - - - S - - - Alpha beta hydrolase
IELDDGJM_04064 6.61e-80 - - - T - - - sh3 domain protein
IELDDGJM_04065 1.05e-81 - - - T - - - sh3 domain protein
IELDDGJM_04070 1.93e-96 - - - L - - - Bacterial transcription activator, effector binding domain
IELDDGJM_04071 1.33e-95 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
IELDDGJM_04073 3.9e-50 - - - O - - - Glutaredoxin
IELDDGJM_04074 3.47e-82 - - - S - - - Ribonucleotide reductase, small chain
IELDDGJM_04075 6.19e-125 - - - L - - - HNH endonuclease
IELDDGJM_04076 1.44e-135 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IELDDGJM_04078 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IELDDGJM_04079 6.39e-157 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IELDDGJM_04080 7.96e-85 - - - S - - - NrdI Flavodoxin like
IELDDGJM_04091 2.52e-26 - - - S - - - Calcineurin-like phosphoesterase
IELDDGJM_04096 3.17e-102 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
IELDDGJM_04097 2.42e-117 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
IELDDGJM_04098 1.3e-53 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
IELDDGJM_04101 1.2e-28 - - - S - - - protein conserved in bacteria
IELDDGJM_04102 0.0 - - - S - - - Bacterial DNA polymerase III alpha subunit
IELDDGJM_04103 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
IELDDGJM_04104 1.15e-286 - - - L - - - DNA primase activity
IELDDGJM_04105 0.0 - - - J - - - DnaB-like helicase C terminal domain
IELDDGJM_04106 7.45e-111 - - - - - - - -
IELDDGJM_04107 6.35e-229 - - - L - - - AAA domain
IELDDGJM_04108 3.18e-208 - - - - - - - -
IELDDGJM_04114 2.23e-239 - - - - - - - -
IELDDGJM_04115 3.43e-163 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
IELDDGJM_04116 4.74e-177 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
IELDDGJM_04118 2.59e-76 - - - - - - - -
IELDDGJM_04126 2.63e-114 - - - S - - - Protein of unknown function (DUF1273)
IELDDGJM_04131 3.18e-84 - - - N - - - bacterial-type flagellum assembly
IELDDGJM_04134 3.99e-05 - - - S - - - YopX protein
IELDDGJM_04141 0.0 - - - - - - - -
IELDDGJM_04148 5.73e-80 - - - - - - - -
IELDDGJM_04153 2.44e-41 - - - S - - - Protein conserved in bacteria
IELDDGJM_04157 7.23e-55 - - - - - - - -
IELDDGJM_04160 0.0 - - - S - - - ATP-dependent DNA helicase activity
IELDDGJM_04162 2.38e-174 - - - S - - - N-methyltransferase activity
IELDDGJM_04163 3.39e-193 - - - S - - - DNA binding
IELDDGJM_04164 3.54e-297 - - - S - - - DNA replication origin binding
IELDDGJM_04166 2.74e-17 - - - K - - - SIR2-like domain
IELDDGJM_04167 2.35e-47 - - - D - - - Tubulin/FtsZ family, GTPase domain
IELDDGJM_04170 0.0 - - - - - - - -
IELDDGJM_04172 1.17e-45 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IELDDGJM_04174 3.21e-267 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
IELDDGJM_04178 3.66e-224 - - - - - - - -
IELDDGJM_04179 0.0 - - - S - - - Terminase-like family
IELDDGJM_04180 0.0 - - - - - - - -
IELDDGJM_04181 0.0 - - - - - - - -
IELDDGJM_04182 7.15e-122 - - - - - - - -
IELDDGJM_04183 3.43e-236 - - - - - - - -
IELDDGJM_04184 2.31e-105 - - - - - - - -
IELDDGJM_04186 8.81e-156 - - - - - - - -
IELDDGJM_04187 4.38e-118 - - - - - - - -
IELDDGJM_04188 2.4e-169 - - - - - - - -
IELDDGJM_04189 5.27e-144 - - - - - - - -
IELDDGJM_04192 7.43e-77 - - - - - - - -
IELDDGJM_04193 3.16e-222 - - - - - - - -
IELDDGJM_04196 1.19e-72 - - - - - - - -
IELDDGJM_04197 2.39e-81 - - - - - - - -
IELDDGJM_04198 7.87e-242 - - - A - - - Belongs to the 'phage' integrase family
IELDDGJM_04202 5.66e-159 - - - - - - - -
IELDDGJM_04203 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IELDDGJM_04204 7.56e-110 - - - S - - - Phage tail protein
IELDDGJM_04205 0.0 - - - S - - - Pfam Transposase IS66
IELDDGJM_04206 6.13e-189 - - - - - - - -
IELDDGJM_04207 0.0 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
IELDDGJM_04208 8.21e-205 - - - - - - - -
IELDDGJM_04209 9.93e-246 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
IELDDGJM_04211 2.05e-51 - - - S - - - Bacteriophage holin
IELDDGJM_04212 9.92e-244 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IELDDGJM_04214 3.38e-123 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IELDDGJM_04215 8.12e-256 - - - L - - - DNA polymerase
IELDDGJM_04216 3.05e-166 - - - S - - - damaged DNA binding
IELDDGJM_04217 3.53e-69 - - - S - - - YolD-like protein
IELDDGJM_04218 2.05e-72 - - - L - - - nuclease activity
IELDDGJM_04219 2.06e-125 - - - J - - - Acetyltransferase (GNAT) domain
IELDDGJM_04220 4.47e-123 yokK - - S - - - SMI1 / KNR4 family
IELDDGJM_04221 8.42e-25 - - - S - - - SMI1-KNR4 cell-wall
IELDDGJM_04222 1.35e-111 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IELDDGJM_04223 3.14e-241 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IELDDGJM_04224 1.2e-106 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IELDDGJM_04225 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IELDDGJM_04226 5.17e-135 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IELDDGJM_04230 3.61e-34 yfhD - - S - - - YfhD-like protein
IELDDGJM_04232 1.08e-89 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
IELDDGJM_04233 3.11e-92 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
IELDDGJM_04234 3.12e-179 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
IELDDGJM_04235 6.51e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
IELDDGJM_04236 3.47e-268 yfhI - - EGP - - - -transporter
IELDDGJM_04237 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
IELDDGJM_04238 8.95e-60 yfhJ - - S - - - WVELL protein
IELDDGJM_04239 1.8e-36 - - - M - - - Glycosyltransferase like family
IELDDGJM_04240 5.33e-152 - - - H - - - Methionine biosynthesis protein MetW
IELDDGJM_04241 1.12e-243 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
IELDDGJM_04242 3.18e-204 - - - H - - - N-terminal domain of galactosyltransferase
IELDDGJM_04243 7.16e-45 - - - H - - - N-terminal domain of galactosyltransferase
IELDDGJM_04246 9.03e-230 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IELDDGJM_04247 3.68e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
IELDDGJM_04248 1.39e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
IELDDGJM_04249 6.97e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IELDDGJM_04250 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IELDDGJM_04252 2.99e-94 - - - - - - - -
IELDDGJM_04253 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
IELDDGJM_04256 2.7e-40 - - - S - - - Domain of unknown function, YrpD
IELDDGJM_04257 4.19e-86 - - - S - - - Domain of unknown function, YrpD
IELDDGJM_04262 8.86e-58 - - - M - - - D-alanyl-D-alanine carboxypeptidase
IELDDGJM_04263 4.76e-15 - - - K - - - Helix-turn-helix XRE-family like proteins
IELDDGJM_04264 0.0 - - - I - - - PLD-like domain
IELDDGJM_04265 4.14e-94 ypoP - - K - - - transcriptional
IELDDGJM_04266 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IELDDGJM_04267 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
IELDDGJM_04268 1.76e-124 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IELDDGJM_04270 3.85e-201 - - - K - - - Transcriptional regulator
IELDDGJM_04271 7.23e-133 trkA - - P ko:K07222 - ko00000 Oxidoreductase
IELDDGJM_04272 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IELDDGJM_04273 7.8e-45 yqfQ - - S - - - YqfQ-like protein
IELDDGJM_04274 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IELDDGJM_04275 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IELDDGJM_04276 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
IELDDGJM_04277 2.21e-198 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IELDDGJM_04278 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
IELDDGJM_04279 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
IELDDGJM_04280 2.38e-80 yqfX - - S - - - membrane
IELDDGJM_04281 2.12e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IELDDGJM_04282 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
IELDDGJM_04283 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
IELDDGJM_04284 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
IELDDGJM_04285 1.31e-147 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
IELDDGJM_04286 1.54e-290 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
IELDDGJM_04287 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
IELDDGJM_04288 7.59e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
IELDDGJM_04289 8.29e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
IELDDGJM_04290 2.14e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
IELDDGJM_04291 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IELDDGJM_04292 1.29e-185 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IELDDGJM_04293 1.09e-93 yqzC - - S - - - YceG-like family
IELDDGJM_04294 2.81e-67 yqzD - - - - - - -
IELDDGJM_04296 2.21e-254 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
IELDDGJM_04297 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IELDDGJM_04298 1.09e-134 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IELDDGJM_04299 3.38e-14 yqgO - - - - - - -
IELDDGJM_04300 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
IELDDGJM_04301 2.11e-42 yqgQ - - S - - - Protein conserved in bacteria
IELDDGJM_04302 1.62e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
IELDDGJM_04303 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IELDDGJM_04304 6.47e-281 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
IELDDGJM_04305 6.33e-255 yqgU - - - - - - -
IELDDGJM_04306 7.34e-66 yqgV - - S - - - Thiamine-binding protein
IELDDGJM_04307 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
IELDDGJM_04308 3.07e-155 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
IELDDGJM_04309 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
IELDDGJM_04310 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
IELDDGJM_04312 7.14e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IELDDGJM_04313 2.35e-304 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IELDDGJM_04314 2.4e-230 yqxL - - P - - - Mg2 transporter protein
IELDDGJM_04315 1.28e-256 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IELDDGJM_04316 4.04e-208 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
IELDDGJM_04317 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
IELDDGJM_04318 3.22e-83 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
IELDDGJM_04319 3.88e-73 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
IELDDGJM_04320 1.17e-59 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
IELDDGJM_04321 1.08e-56 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
IELDDGJM_04322 2.84e-36 yqzE - - S - - - YqzE-like protein
IELDDGJM_04323 3.68e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
IELDDGJM_04324 1.92e-128 yqxM - - - ko:K19433 - ko00000 -
IELDDGJM_04325 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
IELDDGJM_04326 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
IELDDGJM_04327 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
IELDDGJM_04328 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
IELDDGJM_04329 1.07e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
IELDDGJM_04330 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IELDDGJM_04331 7.79e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
IELDDGJM_04332 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IELDDGJM_04333 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IELDDGJM_04334 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
IELDDGJM_04335 5.3e-203 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IELDDGJM_04336 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IELDDGJM_04337 9.94e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IELDDGJM_04338 5.18e-81 yqhP - - - - - - -
IELDDGJM_04339 1.48e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
IELDDGJM_04340 3.27e-120 yqhR - - S - - - Conserved membrane protein YqhR
IELDDGJM_04341 1.94e-100 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
IELDDGJM_04342 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IELDDGJM_04343 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IELDDGJM_04344 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
IELDDGJM_04345 6.75e-216 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
IELDDGJM_04346 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
IELDDGJM_04347 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
IELDDGJM_04348 3.89e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
IELDDGJM_04349 3.11e-256 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
IELDDGJM_04350 2.58e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
IELDDGJM_04351 8.86e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
IELDDGJM_04352 3.31e-133 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
IELDDGJM_04353 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IELDDGJM_04354 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IELDDGJM_04355 9.55e-88 yqhY - - S - - - protein conserved in bacteria
IELDDGJM_04356 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IELDDGJM_04357 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IELDDGJM_04358 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IELDDGJM_04359 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IELDDGJM_04360 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IELDDGJM_04361 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IELDDGJM_04362 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
IELDDGJM_04363 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
IELDDGJM_04364 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
IELDDGJM_04365 7.27e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
IELDDGJM_04366 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IELDDGJM_04368 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IELDDGJM_04369 4.74e-37 - - - - - - - -
IELDDGJM_04370 9.04e-131 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
IELDDGJM_04371 9.7e-168 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IELDDGJM_04372 1.1e-278 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IELDDGJM_04373 2.69e-196 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
IELDDGJM_04374 2.54e-149 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
IELDDGJM_04375 4.15e-144 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IELDDGJM_04376 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
IELDDGJM_04377 1.7e-206 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IELDDGJM_04378 7.43e-45 yqzF - - S - - - Protein of unknown function (DUF2627)
IELDDGJM_04379 0.0 bkdR - - KT - - - Transcriptional regulator
IELDDGJM_04380 4.1e-197 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
IELDDGJM_04381 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IELDDGJM_04382 4.82e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
IELDDGJM_04383 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IELDDGJM_04384 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IELDDGJM_04385 4.67e-233 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IELDDGJM_04386 4.4e-287 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IELDDGJM_04387 6.12e-193 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
IELDDGJM_04388 2.08e-265 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IELDDGJM_04389 5.76e-212 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IELDDGJM_04390 6.29e-100 yqiW - - S - - - Belongs to the UPF0403 family
IELDDGJM_04391 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IELDDGJM_04392 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IELDDGJM_04393 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IELDDGJM_04394 8.94e-224 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
IELDDGJM_04395 4.01e-127 yqjB - - S - - - protein conserved in bacteria
IELDDGJM_04397 4.67e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
IELDDGJM_04398 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IELDDGJM_04399 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
IELDDGJM_04400 1.07e-84 - - - S - - - TIGRFAM germination protein, Ger(x)C family
IELDDGJM_04401 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IELDDGJM_04402 4.11e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
IELDDGJM_04403 8.01e-102 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IELDDGJM_04404 1.43e-293 - - - L - - - COG3666 Transposase and inactivated derivatives
IELDDGJM_04406 6.41e-84 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
IELDDGJM_04407 2.8e-63 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
IELDDGJM_04408 1.59e-65 - - - L - - - Transposase
IELDDGJM_04409 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
IELDDGJM_04410 3.93e-251 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
IELDDGJM_04411 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
IELDDGJM_04412 3.04e-233 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)